Ultrastructural and molecular analyzes of insulin-producing cells induced from human hepatoma cells

References

• Stock PG, Bluestone JA. Beta-cell replacement for type I diabetes. Annu Rev Med. 2004;55:133–56.
   PubMed Web of Science ®Google Scholar
• Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes. Estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047–53.
   PubMed Web of Science ®Google Scholar
• Luft FC. Novel cell therapy for type I diabetes mellitus. J Mol Med. 2009;87:659–61.
   Google Scholar
• Claiborn K, Stoffers DA. Toward a cell-based cure for diabetes: advances in production and transplant of beta cells. Mount Sinai J Med. 2008;75:362–71.
   PubMedGoogle Scholar
• Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, . Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343: 230–8.
   PubMed Web of Science ®Google Scholar
• Robertson RP. Islet transplantation as a treatment for diabetes: a work in progress. N Engl J Med. 2004;350:694–705.
   PubMed Web of Science ®Google Scholar
• Ichii H, Ricordi C. Current status of islet cell transplantation. J Hepatobiliary Pancreat Surg. 2009;16:101–12.
   PubMedGoogle Scholar
• Mohseni Salehi Monfared SS, Larijani B, Abdollahi M. Islet transplantation and antioxidant management: a comprehensive review. World J Gastroenterol. 2009;15:1153–61.
   PubMed Web of Science ®Google Scholar
• D'Amour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG, . Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol. 2006;24:1392–401.
   PubMed Web of Science ®Google Scholar
• de Wert G, Mummery C. Human embryonic stem cells: research, ethics and policy. Hum. Reprod. 2003;18:672–82.
   Google Scholar
• Meier JJ, Bhushan A, Butler AE, Rizza RA, Butler PC. Sustained beta cell apoptosis in long-standing type 1 diabetes: indirect evidence for islet regeneration? Diabetologia. 2005;48: 2221–8.
   PubMed Web of Science ®Google Scholar
• Dor Y, Brown J, Martínez OI, Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature. 2004;249:41–6.
   Google Scholar
• Teta M, Rankin M, Long S, Stein G, Kushner J. Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev Cell. 2007;12:817–26.
   PubMed Web of Science ®Google Scholar
• Slack J, Tosh D. Transdifferentiation and metaplasia: switching cell types. Curr Opin Gen Dev. 2001;11:581–6.
   PubMed Web of Science ®Google Scholar
• Sahu S, Tosh D, Hardikar AA. New sources of β-cells for treating diabetes. J Endocrinol. 2009;202:13–16.
   Google Scholar
• Gurdon JB, Byrne JA, Simonsson S. Nuclear reprogramming and stem cell creation. Proc Natl Acad Sci USA. 2003;100(suppl 1):11819–22.
   Google Scholar
• Cibelli JB, Stice SL, Golueke PJ, Kane JJ, Jerry J, Blackwell C, . Transgenic bovine chimeric offspring produced from somatic cell-derived stem-like cells. Nat Biotechnol. 1998;16: 612–16.
   Google Scholar
• Tada M, Tada T, Lefebvre L, Barton SC, Surani MA. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. EMBO J. 1997;16:6510–20.
   PubMedGoogle Scholar
• Tada M, Takahama Y, Abe K, Nakatsuji N, Tada T. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol. 2001;11:1553–8.
   PubMed Web of Science ®Google Scholar
• Horb ME, Shen CN, Tosh D, Slack JM. Experimental conversion of liver to pancreas. Curr Biol. 2003;13:105–15.
   PubMed Web of Science ®Google Scholar
• Håkelien AM, Gaustad KG, Collas P. Transient alteration of cell fate using a nuclear and cytoplasmic extract of an insulinoma cell line. Biochem Biophys Res Commun. 2004;316:834–41.
   Google Scholar
• Peran M, Marchal JA, Lopez E, Jimenez-Navarro M, Boulaiz H, Rodríguez-Serrano F, . Human cardiac tissue induces transdifferentiation of adult stem cells towards cardiomyocytes. Cytotherapy. 2010;12:332–7.
   PubMed Web of Science ®Google Scholar
• Li W-C, Horb ME, Tosh D, Slack JMW. In vitro transdifferentiation of hepatoma cells into functional pancreatic cells. Mech Devel. 2005;122:835–47.
   Google Scholar
• Kawasaki H, Mizuguchi T, Kikkawa Y, Oshima H, Sasaki Y, Tokino T, . In vitro transformation of adult rat hepatic progenitor cells into pancreatic endocrine hormone-producing cells. J Hepatobil Panc Surg. 2008;15:310–17.
   Google Scholar
• Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87:4–14.
   PubMed Web of Science ®Google Scholar
• Bargsten G. Cytological and immunocytochemical characterization of the insulin secreting insulinoma cell line RINm5F. Arch Histol Cytol. 2004;67:79–94.
   Google Scholar
• Chick WL, Warren S, Chute RN, Like AA, Lauris V, Kitchen KC. A transplantable insulinoma in the rat. Proc Natl Acad Sci USA. 1977;74:628–32.
   PubMed Web of Science ®Google Scholar
• Cao LZ, Tang DQ, Horb ME, Li SW, Yang LJ. High glucose is necessary for complete maturation of Pdx1-VP16-expressing hepatic cells into functional insulin-producing cells. Diabetes. 2004;53:3168–78.
   PubMed Web of Science ®Google Scholar
• Zalzman M, Gupta S, Giri RK, Berkovich I, Sappal BS, Karnieli O, . Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells. Proc Natl Acad Sci USA. 2003;100: 7253–8.
   PubMed Web of Science ®Google Scholar
• Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature. 2008;455:627–32.
   PubMed Web of Science ®Google Scholar
• Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoter factor 1 is required for pancreas development in mice. Nature. 1994;371:606–9.
   PubMed Web of Science ®Google Scholar
• Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet. 1997;15:106–10.
   PubMed Web of Science ®Google Scholar
• Ber I, Shternhall K, Perl S, Ohanuna Z, Goldberg I, Barshack I, . Functional, persistent, and extended liver to pancreas transdifferentiation. J Biol Chem. 2003;278:31950–7.
   PubMed Web of Science ®Google Scholar
• Motoyama H, Ogawa S, Kubo A, Miwa S, Nakayama J, Tagawa Y-I, Miyagawa S. In vitro reprogramming of adult hepatocytes into insulin-producing cells without viral vectors. Biochem Biophys Res Comm. 2009;385:123–8.
   Google Scholar