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Original Article

The aggregate nature of human mesenchymal stromal cells in native bone marrow

, , , , , , , , & show all
Pages 917-924 | Received 10 Oct 2011, Accepted 24 Apr 2012, Published online: 11 Jun 2012

References

  • Dinarvand P, Hashemi SM, Soleimani M. Effect of transplantation of mesenchymal stem cells induced into early hepatic cells in streptozotocin-induced diabetic mice. Biol Pharm Bull. 2010;33:1212–7.
  • Shafiee A, Soleimani M, Chamheidari GA, Seyedjafari E, Dodel M, Atashi A, . Electrospun nanofiber based regeneration of cartilage enhanced by mesenchymal stem cells. J Biomed Mat Res A. 2011;99(3):467–78.
  • Nombela-Arrieta C, Ritz J, Silberstein LE. The elusive nature and function of mesenchymal stem cells. Nat Rev Mol Cell Biol. 2011;12:126–31.
  • Wagner W, Ho AD. Mesenchymal stem cell preparations: comparing apples and oranges. Stem Cell Rev. 2007;3: 239–48.
  • Prockop DJ, Olson SD. Clinical trials with adult stem/ progenitor cells for tissue repair: let's not overlook some essential precautions. Blood. 2007;109:3147–51.
  • Tondreau T, Lagneaux L, Dejeneffe M, Delforge A, Massy M, Mortier C, . Isolation of BM mesenchymal stem cells by plastic adhesion or negative selection: phenotype, proliferation kinetics and differentiation potential. Cytotherapy. 2004;6:372–9.
  • Dennis JE, Carbillet JP, Caplan AI, Charbord P. The STRO-1 + marrow cell population is multipotential. Cells Tissues Organs. 2002;170:73–82.
  • Reyes M, Lund T, Lenvik T, Aguiar D, Koodie L, Verfaillie CM. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood. 2001;98: 2615–25.
  • Ahmadbeigi N, Soleimani M, Gheisari Y, Vasei M, Amanpour S, Bagherizadeh I, . Dormant phase and multinuclear cells: two key phenomena in early culture of murine bone marrow mesenchymal stem cells. Stem Cells Dev. 2011;20(8):1337–47.
  • Torsvik A, Rosland GV, Svendsen A, Molven A, Immervoll H, McCormack E, . Spontaneous malignant transformation of human mesenchymal stem cells reflects cross- contamination: putting the research field on track. Letter. Cancer Res. 2010;70:6393–6.
  • Horwitz EM, Gordon PL, Koo WK, Marx JC, Neel MD, McNall RY, . Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proc Natl Acad Sci USA. 2002;99:8932–7.
  • Le Blanc K, Rasmusson I, Sundberg B, Gotherstrom C, Hassan M, Uzunel M, . Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet. 2004;363:1439–41.
  • Seeger FH, Tonn T, Krzossok N, Zeiher AM, Dimmeler S. Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction. Eur Heart J. 2007;28:766–72.
  • Simmons PJ, Torok-Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood. 1991;78:55–62.
  • Quirici N, Soligo D, Bossolasco P, Servida F, Lumini C, Deliliers GL. Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodies. Exp Hematol. 2002;30:783–91.
  • Heino TJ, Hentunen TA, Vaananen HK. Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts. Exp Cell Res. 2004;294:458–68.
  • Schecroun N, Delloye C. In vitro growth and osteoblastic differentiation of human bone marrow stromal cells supported by autologous plasma. Bone. 2004;35:517–24.
  • Stute N, Holtz K, Bubenheim M, Lange C, Blake F, Zander AR. Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use. Exp Hematol. 2004;32:1212–25.
  • Doucet C, Ernou I, Zhang Y, Llense JR, Begot L, Holy X, . Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications. J Cell Physiol. 2005;205:228–36.
  • Chaudhary LR, Hofmeister AM, Hruska KA. Differential growth factor control of bone formation through osteoprogenitor differentiation. Bone. 2004;34:402–11.
  • Ahmadbeigi N, Shafiee A, Seyedjafari E, Gheisari Y, Vassei M, Amanpour S, . Early spontaneous immortalization and loss of plasticity of rabbit bone marrow mesenchymal stem cells. Cell Prolif. 2011;44:67–74.
  • Horn P, Bork S, Diehlmann A, Walenda T, Eckstein V, Ho AD, . Isolation of human mesenchymal stromal cells is more efficient by red blood cell lysis. Cytotherapy. 2008;10: 676–85.
  • Horn P, Bork S, Wagner W. Standardized isolation of human mesenchymal stromal cells with red blood cell lysis. Methods Mol Biol. 2011;698:23–35.
  • Bacigalupo A, Tong J, Podesta M, Piaggio G, Figari O, Colombo P, . Bone marrow harvest for marrow transplantation: effect of multiple small (2 ml) or large (20 ml) aspirates. Bone Marrow Transplant. 1992;9:467–70.
  • Muschler GF, Boehm C, Easley K. Aspiration to obtain osteoblast progenitor cells from human bone marrow: the influence of aspiration volume. J Bone Joint Surg Am. 1997;79: 1699–709.
  • Jin JD, Wang HX, Xiao FJ, Wang JS, Lou X, Hu LD, . A novel rich source of human mesenchymal stem cells from the debris of bone marrow samples. Biochem Biophys Res Commun. 2008;376:191–5.
  • Dvorakova J, Hruba A, Velebny V, Kubala L. Isolation and characterization of mesenchymal stem cell population entrapped in bone marrow collection sets. Cell Biol Int. 2008; 32:1116–25.
  • Insausti CL, Blanquer MB, Olmo LM, Lopez-Martinez MC, Ruiz XF, Lozano FJ, . Isolation and characterization of mesenchymal stem cells from the fat layer on the density gradient separated bone marrow. Stem Cells Dev. 2012;21(2):260–72.
  • Blazsek I, Misset JL, Comisso M, Mathe G. Hematon: a multicellular functional unit in primary hematopoiesis. Biomed Pharmacother. 1988;42:661–8.
  • Boiret N, Rapatel C, Boisgard S, Charrier S, Tchirkov A, Bresson C, . CD34 + CDw90(Thy-1) + subset colocated with mesenchymal progenitors in human normal bone marrow hematon units is enriched in colony-forming unit megakaryocytes and long-term culture-initiating cells. Exp Hematol. 2003;31:1275–83.
  • Bruder SP, Fink DJ, Caplan AI. Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy. J Cell Biochem. 1994;56:283–94.
  • Campagnoli C, Roberts IA, Kumar S, Bennett PR, Bellantuono I, Fisk NM. Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow. Blood. 2001;98:2396–402.
  • Gangji V, Hauzeur JP, Matos C, De Maertelaer V, Toungouz M, Lambermont M. Treatment of osteonecrosis of the femoral head with implantation of autologous bone- marrow cells. A pilot study. J Bone Joint Surg Am. 2004;86-A:1153–60.
  • Prockop DJ, Azizi SA, Colter D, Digirolamo C, Kopen G, Phinney DG. Potential use of stem cells from bone marrow to repair the extracellular matrix and the central nervous system. Biochem Soc Trans. 2000;28:341–5.
  • Hernigou P, Poignard A, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am. 2005;87:1430–7.
  • Wexler SA, Donaldson C, Denning-Kendall P, Rice C, Bradley B, Hows JM. Adult bone marrow is a rich source of human mesenchymal ‘stem’ cells but umbilical cord and mobilized adult blood are not. Br J Haematol. 2003;121: 368–74.
  • Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol. 2008;8:726–36.

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