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Research Article

Pharmacokinetic parameters and a theoretical study about metabolism of BR-AEA (a salbutamol derivative) in rabbit

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Pages 340-346 | Received 13 Mar 2009, Accepted 09 Jul 2009, Published online: 29 Oct 2009

References

  • Fitzgerald MA. Managing bronchospasm with short-acting beta(2)-agonists. Nurse Pract 2006;31:47–53.
  • De Galan BE, De Mol P, Wennekes L, Schouwenberg BJ, Smits PJ. Preserved sensitivity to β2-adrenergic receptor agonists in patients with type 1 diabetes mellitus and hypoglycemia unawareness. J Clin Endocrinol Metab 2006;91:2878–84.
  • van Baak MA, Mayer LH, Kempinski RE, Hartgens F. Effect of salbutamol on muscle strength and endurance performance in nonasthmatic men. Med Sci Sports Exerc 2000;32:1300–6.
  • Burgraaf J, Westendorp RG, in’t Veen JC, Schoemaker RC, Sterk PJ, Cohen AF, et al. Cardiovascular side effects of inhaled salbutamol in hypoxic asthmatic patients. Thorax 2000;56:567–9.
  • Raghunathan K, Nagajothi N. Paradoxical bronchospasm: a potentially life threatening adverse effect of salbutamol. South Med J 2006;99:288–9.
  • Janson C, Boe J, Boman G, Mossberg B, Svedmyr N. Bronchodilator intake and plasma levels on admission for severe acute asthma. Eur Respir J 1992;5:80–5.
  • Anderson PJ, Zhou X, Breen P, Gann L, Logsdon TW, Compadre CM, et al. Pharmacokinetics of (R,S)-salbutamol after aerosol inhalation in healthy adult volunteers. J Pharm Sci 1998;87:841–4.
  • Perreault S, Dumont L, Villiere V, Ong H, Adam A, du Souich P. Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits. Drug Metab Dispos 1993;21:485–91.
  • Boulton DW, Fawcett JP. The pharmacokinetics of levosalbutamol: what are the clinical implications? Clin Pharmacokinet 2001;40:23–40.
  • Dombrovski L, Dong A, Bochkarev A, Plotnikov AN. Crystal structures of human sulfotransferases SULT1B1and SULT1C1 complexed with the cofactor product adenosine-3-5-diphosphate (PAP). Proteins 2006;64:1091–4.
  • Riley E, Bolton-Grob R, Liyou N, Wong C, Tresillian M, McManus ME. Isolation and characterization of a novel rabbit sulfotransferase isoform belonging to the SULT1A subfamily. Int J Biochem Cell Biol 2002;34:958–69.
  • Morgan DJ, Paull JD, Richmond BH, Wilson-Evered E, Ziccone SP. Pharmacokinetics of intravenous and oral salbutamol and its sulphate conjugate. Br J Clin Pharmacol 1986;22:587–93.
  • Soriano-Ursúa MA, Valencia-Hernández I, Arellano-Mendoza MG, Correa-Basurto J, Trujillo-Ferrara JG. Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo[4.4.0]deca-7,9,11-trien-9-yl)-2-(tert-butyl-amino)ethanol, a compound designed to act as a β2 adrenoceptor agonist. Eur J Med Chem 2009;44:2840–6.
  • Tafi A, Agamennone M, Tortorella P, Alcaro S, Gallina C, Botta M. AMBER force field implementation of the boronate function to simulate the inhibition of β-lactamases by alkyl and aryl boronic acids. Eur J Med Chem 2005;40:1134–42.
  • Miller LG, Greenblatt DJ. Determination of salbutamol in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 1986;381:205–8.
  • Smith DJ. The pharmacokinetics, metabolism, and tissue residues of β-adrenergic agonists in livestock. J Anim Sci 1998;76:173–94.
  • Shao F, Wang G, Xie H, Zhu X, Sun JA. Pharmacokinetic study of triptolide, a constituent of immunosuppressive Chinese herb medicine in rats. Biol Pharm Bull 2007;30:702–7.
  • Perreault S, Ong H, Du Souich P. Salbutamol disposition and dynamics in conscious rabbits: influence of the route of administration and of the dose. J Pharmacokinet Biopharm 1992;20:461–76.
  • Frisch MJ, et al. GAUSSIAN 98, Revision A.9. Pittsburgh, PA:Gaussian, Inc., 1998.
  • Morris GM, Goodsell DS, Halliday RS, Huey R, Hart WE, Belew RK, et al. Automated docking using a Lamarckian genetic algorithm and empirical binding free energy function. J Comput Chem 1998; 19:1639–62.
  • Schwede T, Kopp J, Guex N, Peitsch MC. SWISS-MODEL: an automated protein homology-modeling server. Nucleic Acids Res 2003;31:3381–5.
  • Guex N, Peitsch MC. Swiss Model and the Swiss-PDBViewer: an environment for comparative protein modeling. Electrophoresis 1997;18:2714–23.
  • Humphrey W, Dalke A, Schulten K. VMD: visual molecular dynamics. J Mol Graph 1996;14:33–8.
  • Han Y, Lv Z, Jiang T, Wang Y. Bioanalysis and pharmacokinetics of chitosan ester in rabbit serum by HPLC with postcolumn fluorescence derivatization. J Chromatogr B 2007;845:138–42.
  • Dajani R, Hood AM, Coughtri MWH. A single amino acid, Glu146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3. Mol Pharm 1998;54:942–8.
  • Walle UK, Pesola GR, Walle T. Stereoselective sulphate conjugation of salbutamol in humans: comparison of hepatic, intestinal and platelet activity. Br J Clin Pharmacol 1993;35:413–18.
  • Tsoi C, Widersten M, Morgenstern R, Swedmark S. Amino acid residue 247 in canine sulfotransferase SULT1D1: a new determinant of substrate selectivity. Biochem J 2004;378:687–92.
  • Pacifici GM. Inhibition of human liver and duodenum sulfotransferases by drugs and dietary chemicals: a review of the literature. Int J Clin Pharmacol Ther 2004;42:488–95.
  • Barnett AC, Tsvetanov S, Gamage N, Martin JL, Duggleby RG, McManus ME. Active site mutations and substrate inhibition in human sulfotransferase 1A1 and 1A3. J Biol Chem 2004;279:18799–805.
  • Romero-Huerta J. Síntesis, caracterización y evaluación de la farmacocinética del borato de R-ariletilamina en conejo. Master’s Thesis, Escuela Superior de Medicina-IPN, México, 2006.
  • Feakes DA, Shelly K, Hawthorne MF. Selective boron delivery to murine tumors by lipophilic species incorporated in the membranes of unilamellar liposomes. Proc Natl Acad Sci 1995;92:1367–70.

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