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Research Article

Synthesis of some N-[4-(benzothiazole-2yl) phenyl]-2-aryloxyacetamide derivatives and their anticancer activities

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Pages 515-520 | Received 22 Feb 2011, Accepted 18 Jun 2011, Published online: 08 Aug 2011

References

  • Prat WB, Ruddon RW, Ensminger WD, Maybaum J. The Anticancer Drugs. 2nd Ed., Oxford: Oxford University Press, 1994.
  • Baguley BC, Kerr DJ. Anticancer Drug Development. New York: Academic Pres, 2002.
  • Adjei AA, Buolamwini JK. Novel Anticancer Agents, Strategies for Discovery and Clinical Testing. New York: Elsevier Academic Press, 2006.
  • Shi DF, Bradshaw TD, Wrigley S, McCall CJ, Lelieveld P, Fichtner I et al. Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo. J Med Chem 1996;39:3375–3384.
  • Chua MS, Shi DF, Wrigley S, Bradshaw TD, Hutchinson I, Shaw PN et al. Antitumor benzothiazoles. 7. Synthesis of 2-(4-acylaminophenyl)benzothiazoles and investigations into the role of acetylation in the antitumor activities of the parent amines. J Med Chem 1999;42:381–392.
  • Shi DF, Bradshaw TD, Chua MS, Westwell AD, Stevens MF. Antitumour benzothiazoles. Part 15: The synthesis and physico-chemical properties of 2-(4-aminophenyl)benzothiazole sulfamate salt derivatives. Bioorg Med Chem Lett 2001;11:1093–1095.
  • Tzanopoulou S, Sagnou M, Paravatou-Petsotas M, Gourni E, Loudos G, Xanthopoulos S et al. Evaluation of Re and (99m)Tc complexes of 2-(4′-aminophenyl)benzothiazole as potential breast cancer radiopharmaceuticals. J Med Chem 2010;53:4633–4641.
  • Kashiyama E, Hutchinson I, Chua MS, Stinson SF, Phillips LR, Kaur G et al. Antitumor benzothiazoles. 8. Synthesis, metabolic formation, and biological properties of the C- and N-oxidation products of antitumor 2-(4-aminophenyl)benzothiazoles. J Med Chem 1999;42:4172–4184.
  • Hutchinson I, Jennings SA, Vishnuvajjala BR, Westwell AD, Stevens MF. Antitumor benzothiazoles. 16. Synthesis and pharmaceutical properties of antitumor 2-(4-aminophenyl)benzothiazole amino acid prodrugs. J Med Chem 2002;45:744–747.
  • Hutchinson I, Chua MS, Browne HL, Trapani V, Bradshaw TD, Westwell AD, Stevens MFG. Antitumor benzothiazoles.14.1 Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles. J Med Chem 2001;44:1447–1455.
  • Henriksen G, Hauser AI, Westwell AD, Yousefi BH, Schwaiger M, Drzezga A et al. Metabolically stabilized benzothiazoles for imaging of amyloid plaques. J Med Chem 2007;50:1087–1089.
  • Serdons K, Verduyckt T, Cleynhens J, Terwinghe C, Mortelmans L, Bormans G et al. Synthesis and evaluation of a (99m)Tc-BAT-phenylbenzothiazole conjugate as a potential in vivo tracer for visualization of amyloid beta. Bioorg Med Chem Lett 2007;17:6086–6090.
  • Tasler S, Müller O, Wieber T, Herz T, Krauss R, Totzke F et al. N-substituted 2′-(aminoaryl)benzothiazoles as kinase inhibitors: hit identification and scaffold hopping. Bioorg Med Chem Lett 2009;19:1349–1356.
  • Krasavin M, Karapetian R, Konstantinov I, Gezentsvey Y, Bukhryakov K, Godovykh E et al. Discovery and potency optimization of 2-amino-5-arylmethyl-1,3-thiazole derivatives as potential therapeutic agents for prostate cancer. Arch Pharm (Weinheim) 2009;342:420–427.
  • Boyd MR. Status of the NCI preclinical antitumor drug discovery screen principles and practice of oncology 1989;3:2.

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