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Original Article

Implication of novel thiazolo-thiophene derivative (MCD-KV-10) for management of asthma

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Pages 229-239 | Received 29 Sep 2013, Accepted 26 Mar 2014, Published online: 18 Jun 2014

References

  • Fredholm BB, IJzerman AP, Jacobson KA, et al. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 2001;53:527–52
  • Fredholm BB, Abbracchio MP, Burnstock G, et al. Nomenclature and classification of purinoceptors. Pharmacol Rev 1994;46:143–6
  • Martin RJ, Kraft M, Chu HW, et al. A link between chronic asthma and chronic infection. J Allergy Clin Immunol 2001;107:595–601
  • Meade CJ, Worrall L, Hayes D, Protin U. Induction of interleukin 8 release from the HMC-1 mast cell line: synergy between stem cell factor and activators of the adenosine A(2b) receptor. Biochem Pharmacol 2002;64:317–25
  • Cronstein BN, Daguma L, Nichols D, et al. The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively. J Clin Invest 1990;85:1150–7
  • Cronstein BN, Levin RI, Philips M, et al. Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol 1992;148:2201–6
  • Salmon JE, Cronstein BN. Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory. J Immunol 1990;145:2235–40
  • Marone G, Petracca R, Vigorita S, et al. Adenosine receptors on human leukocytes IV. Characterization of an A1/Ri receptor. Int J Clin Lab Res 1992;22:235–42
  • Salmon JE, Brogle N, Brownlie C, et al. Human mononuclear phagocytes express adenosine A1 receptors. A novel mechanism for differential regulation of Fc gamma receptor function. J Immunol 1993;151:2775–85
  • Ahmed AH, Jacobson KA, Kim J, Heppel LA. Presence of both A1 and A2A adenosine receptors in human cells and their interactions. Biochem Biophys Res Commun 1995;208:871–8
  • Peachell PT, Columbo M, Kagey-Sobotka A, et al. Adenosine potentiates mediator release from human lung mast cells. Am Rev Respir Dis 1988;138:1143–51
  • Forsythe P, McGarvey LPA, Heaney LG, et al. Adenosine induces histamine release from human bronchoalveolar lavage mast cells. Clin Sci 1999;96:349–55
  • Murakami S, Hashikawa T, Saho T, et al. Adenosine regulates the IL-1β induced cellular functions of human gingival fibroblasts. Int Immunol 2001;13:1533–40
  • Panther E, Idzko M, Herouy Y, et al. Expression and function of adenosine receptors in human dendritic cells. FASEB J 2001;15:1963–70
  • Wilson CN, Batra VK. Lipopolysaccharide binds to and activates A1 adenosine receptors on human pulmonary artery endothelial cells. J Endotoxin Res 2002;8:263–71
  • McNamara N, Gallup M, Khong A, et al. Adenosine up-regulation of the mucin gene, MUC2, in asthma. FASEB J 2004;18:1770–2
  • Ethier MF, Madison JM. Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells. Am J Respir Cell Mol Biol 2006;35:496–502
  • Clark AN, Youkey R, Liu X, et al. A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circ Res 2007;101:1130–8
  • Brown RA, Clarke GW, Ledbetter CL, et al. Elevated expression of adenosine A1 receptor in bronchial biopsies from asthmatic subjects. Eur Respir J 2008;31:1–9
  • Bjorck T, Gustafsson LE, Dahlen SE. Isolated bronchi from asthmatics are hyper responsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine. Am Rev Respir Dis 1992;145:1087–91
  • Hughes PJ, Holgate ST, Church MK. Adenosine inhibits and potentiates IgE-dependent histamine release from human lung mast cells by an A2-purinoceptor mediated mechanism. Biochem Pharmacol 1984;33:3847–52
  • Peachell PT, Lichtenstein LM, Schleimer RP. Differential regulation of human basophil and lung mast cell function by adenosine. J Pharmacol Exp Ther 1991;256:717–26
  • Suzuki H, Takei M, Nakahata T, Fukamachi H. Inhibitory effect of adenosine on degranulation of human cultured mast cells upon cross-linking of Fc epsilon RI. Biochem Biophys Res Commun 1998;242:697–702
  • Felsch A, Stocker K, Borchard U. Phorbol ester-stimulated adherence of neutrophils to endothelial cells is reduced by adenosine A2 receptor agonists. J Immunol 1995;155:333–8
  • Wollner A, Wollner S, Smith JB. Acting via A2 receptors, adenosine inhibits the upregulation of Mac-1 (Cd11b/CD18) expression on FMLP-stimulated neutrophils. Am J Respir Cell Mol Biol 1993;9:179–85
  • Fredholm BB, Zhang Y, Van der Ploeg I. Adenosine A2A receptors mediate the inhibitory effect of adenosine on formyl-Met-Leu-Phe-stimulated respiratory burst in neutrophil leucocytes. Naunyn Schmiedebergs Arch Pharmacol 1996;354:262–7
  • Hannon JP, Bray-French KM, Phillips RM, Fozard JR. Further pharmacological characterization of the adenosine receptor subtype mediating inhibition of oxidative burst in human isolated neutrophils. Drug Dev Res 1998;43:214–24
  • Bouma MG, Jeunhomme TM, Boyle DL, et al. Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors. J Immunol 1997;158:5400–8
  • Huang S, Apasov S, Koshiba M, Sitkovsky M. Role of A2A extracellular adenosine receptor-mediated signaling in adenosine mediated inhibition of T-cell activation and expansion. Blood 1997;90:1600–6
  • Fishman P, Bar-Yehuda S. Pharmacology and therapeutic applications of A3 receptor subtypes. Curr Topics Med Chem 2003;3:463–9
  • Nadeem A, Mustafa SJ. Adenosine receptor anatagonists and asthma. Drug Discov Today Ther Strat 2006;3:269–75
  • Scheiff AB, Yerande SG, Tayeb AE, et al. 2-Amino-5-benzoyl-4-phenylthiazoles: development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem 2010;18:2195–203
  • Slater JW, Zechnich AD, Haxby DG. Second generation antihistamines: a comparative review. Drugs 1999;57:31–47
  • Gilman A, Goodman L, Rall T, Murad F. Goodman and Gilman’s – the pharmacological basis of therapeutics. USA: Macmillan; 2010:659–60
  • Klotz KN, Hessling J, Hegler J, et al. Comparative pharmacology of human adenosine receptor subtypes – characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's Arch Pharmacol 1998;357:1–9
  • Klotz KN, Falgner N, Kachler S, et al. [3H]HEMADO – a novel tritiated agonist selective for the human adenosine A3 receptor. Eur J Pharmacol 2007;556:14–18
  • De Lean A, Hancock AA, Lefkowitz RJ. Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. Mol Pharmacol 1982;21:5–16
  • Cheng Y, Prusoff WH. Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 1973;22:3099–108
  • Sircar JC, Schwender CF, Johnson EA. Soyabean lipoxygenase inhibition by nonsteroidal anti-inflammatory drugs. Prostaglandins 1983;25:393–6
  • Gaffney BJ. Lipoxygenases: structural principles and spectroscopy. Annu Rev Biophys Biomol Struct 1996;25:431–59
  • Mahesha HG, Singh SA, Rao AGA. Inhibition of lipoxygenase by soy isoflavones: evidence of isoflavones as redox inhibitors. Arch Biochem Biophys 2007;461:176–85
  • Harish MS, Nagur M, Badami S. Antihistaminic and mast cell stabilizing activity of Striga orobanchioides. J Ethnopharmacol 2001;76:197–200
  • Duan W, Kua IC, Selvarajan S, et al. Anti-inflammatory effects of genistein, a tyrosine kinase inhibitor, on guinea pig model of asthma. Am J Respir Crit Care Med 2003;167:185–92
  • Shore PA, Burkhalter A, Cohn VH. A method for the fluorometric assay of histamine in tissues. J Pharmacol Exp Ther 1959;127:182–6
  • Busse WW, Lemanske JR. Advances in immunology: asthma. N Engl J Med 2001;344:350–62
  • Kips JC. Cytokines in asthma. Eur Respir J 2001;18:S24–33
  • Chung KF, Barnes PJ. Cytokines in asthma. Thorax 1999;54:825–57
  • Mahajan SG, Mehta AA. Role of cytokines in pathophysiology of asthma. Ir J Pharmacol Ther 2006;5:1–14
  • Schellenberg RR, Foster A, Duff MJ. Anti-IgE induced contraction of human bronchus in vitro. J Allergy Clin Immun 1985;75:126–30
  • Phillips GD, Holgate ST. Interaction of inhaled LTC4 with histamine and PGD2 on airway caliber in asthma. J Appl Physiol 1989;66:304–12
  • Engineer DM, Morris HR, Piper PJ, Sirois P. The release of prostaglandins and thromboxanes from guinea-pig lung by slow reacting substance, of anaphylaxis, and its inhibition. Br J Pharmacol 1978;64:211–18
  • Haskó G, Linden J, Cronstein B, Pacher P. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 2008;7:759–70
  • Eum SY, Karim M, Hamid Q, et al. Involvement of the cysteinyl-leucotrienes in allergen-induced airways eosinophilia and hyperresponsiveness in the mouse. Am J Respir Cell Mol Biol 2003;8:25–32
  • Mahajan SG, Banerjee A, Chauhan BF, et al. Inhibitory effect of n-butanol fraction of Moringa oleifera Lam. seeds on ovalbumin-induced airway inflammation in a guinea pig model of asthma. Int J Toxicol 2009;28:519–27
  • Ngoc LP, Gold DR, Tzianabos AO, et al. Cytokines, allergy, and asthma. Curr Opin Allergy Clin Immunol 2005;5:161–6

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