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Short Communication

In vitro neuroprotective activity of sesquiterpenoids from the flower buds of Tussilago farfara

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Pages 852-856 | Received 21 Jul 2014, Accepted 11 Sep 2014, Published online: 07 Oct 2014

References

  • McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson’s and Alzheimer’s disease brains. Neurology 1988;38:1285–91
  • Perry VH, Gordon S. Macrophages and microglia in the nervous system. Trends Neurosci 1988;11:273–7
  • Streit WJ, Graeber MB, Kreutzberg GW. Functional plasticity of microglia: a review. Glia 1988;1:301–7
  • McGeer PL, McGeer EG. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Brain Res Rev 1995;21:195–218
  • Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 2007;8:57–69
  • McGeer PL, Kawamata T, Walker DG, et al. Microglia in degenerative neurological disease. Glia 1993;7:84–92
  • Giulian D, Haverkamp LJ, Li J, et al. Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain. Neurochem Int 1995;27:119–37
  • McGeer EG, McGeer PL. Inflammatory processes in Alzheimer’s disease. Prog Neuropsychopharmacol Biol Psychiatry 2003;27:741–9
  • Necela BM, Su W, Thompson EA. Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor gamma and nuclear factor-κB in macrophages. Immunology 2008;125:344–58
  • Huh J. Donguibogam: principles and practice of eastern medicine. Seoul, Korea: Ministry of Health, Welfare and Family Affairs; 2010: 1613
  • Cho J, Kim HM, Ryu JH, et al. Neuroprotective and antioxidant effects of the ethyl acetate fraction prepared from Tussilago farfara L. Biol Pharm Bull 2005;28:455–60
  • Kokoska L, Polesny Z, Rada V, et al. Screening of some Siberian medicinal plants for antimicrobial activity. J Ethnopharmacol 2002;82:51–3
  • Ryu JH, Jeong YS, Sohn DH. A new bisabolene epoxide from Tussilago farfara, and inhibition of nitric oxide synthesis in LPS-activated macrophages. J Nat Prod 1999;62:1437–8
  • Mahdi H, Schlick CJ, Kowk LL, et al. Endometrial cancer in Asian and American Indian/Alaskan Native women: tumor characteristics, treatment and outcome compared to non-Hispanic white women. Gynecol Oncol 2014;132:443–9
  • Lim HJ, Lee HS, Ryu JH. Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression by tussilagone from Farfarae flos in BV-2 microglial cells. Arch Pharm Res 2008;31:645–52
  • Green LC, et al. Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal Biochem 1982;126:131–8
  • Zujovic V, Taupin V. Use of cocultured cell systems to elucidate chemokine-dependent neuronal/microglial interactions: control of microglial activation. Methods 2003;29:345–50
  • Ferdinand Bohlmanna RKG, Jakupovica J, Kinga RM, Robinson H. Four volcanoes and bisabolone derivatives from Rugelia nudicaulis. Phytochemistry 1982;21:1665–8
  • Kikuchi M, Suzuki N. Studies on the constituents of Tussilago farfara L. II Structures of new sesquiterpenoids isolated from the flower buds. Chem Pharm Bull 1992;40:2753–5
  • Ferdinand Bohlmann CZ, Gupta RK. Notonipetrone-like sesquiterpenes from Senecio kleinia. Phytochemistry 1981;20:2024–6

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