1,272
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Synthesis and evaluation of naphthalene-based thiosemicarbazone derivatives as new anticancer agents against LNCaP prostate cancer cells

, , , , , & show all
Pages 410-416 | Received 19 Dec 2014, Accepted 05 Mar 2015, Published online: 31 Mar 2015

References

  • Silverstein A, Silverstein V, Nunn Silverstein L. Cancer. Minneapolis (MN): Twenty-First Century Books; 2006
  • Gerritsen WR. The evolving role of immunotherapy in prostate cancer. Ann Oncol 2012;23:22–7
  • Culig Z. Proinflammatory cytokine interleukin-6 in prostate carcinogenesis. Am J Clin Exp Urol 2014;2:231–8
  • Kung HJ, Evans CP. Oncogenic activation of androgen receptor. Urol Oncol 2009;27:48–52
  • Suzuki H, Ueda T, Ichikawa T, Ito H. Androgen receptor involvement in the progression of prostate cancer. Endocr Relat Cancer 2003;10:209–16
  • Chuu CP, Kokontis JM, Hiipakka RA, et al. Androgens as therapy for androgen receptor positive castration-resistant prostate cancer. J Biomed Sci 2011;18:1–11
  • Culig Z, Klocker H, Bartsch G, Hobisch A. Androgen receptors in prostate cancer. Endocr Relat Cancer 2002;9:155–70
  • Nouri M, Ratther E, Stylianou N, et al. Androgen-targeted therapy-induced epithelial mesenchymal plasticity and neuroendocrine transdifferentiation in prostate cancer: an opportunity for intervention. Front Oncol 2014;4:371–6
  • Yu Y, Kalinowski DS, Kovacevic Z, et al. Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductas inhibitors. J Med Chem 2009;52:5271–94
  • Chapman TR, Kinsella TJ. Ribonucleotide reductase inhibitor s: a new look at an old target for radiosensitization. Front Oncol 2012;1:1–6
  • Moorthy NS, Cerqueira NM, Ramos MJ, Fernandes PA. Aryl- and heteroaryl-thiosemicarbazone derivatives and their metal complexes: a pharmacological template. Rec Pat Anticancer Drug Discov 2013;8:168–82
  • Kalinowski DS, Quach P, Richardson DR. Thiosemicarbazones: the new wave in cancer treatment. Future Med Chem 2009;1:1143–51
  • Álvarez C, Álvarez R, Corchete P, et al. Synthesis and biological activity of naphthalene analogues of phenstatins: naphthylphenstatins. Bioorg Med Chem Lett 2007;17:3417–20
  • Jiang S, Crogan-Grundy C, Drewe J, et al. Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl-N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay. Bioorg Med Chem Lett 2008;18:5725–8
  • Yuan JW, Wang SF, Luo ZL, et al. Synthesis and biological evaluation of compounds which contain pyrazole, thiazole and naphthalene ring as antitumor agents. Bioorg Med Chem Lett 2014;24:2324–8
  • Halder AK, Adhikary N, Maity MK, Jha T. Synthesis, pharmacological activity and comparative QSAR modeling of 1,5-N,N′-substituted-2-(substituted naphthalenesulphonyl)glutamamides as possible anticancer agents. Eur J Med Chem 2010;45:1760–71
  • Rasolofonjatovo E, Provot O, Hamze A, et al. Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: synthesis, cytotoxicity and antitubulin activity. Eur J Med Chem 2012;52:22–32
  • Lokhande TN, Viswanathan CL, Joshia A, Juvekarb A. Design, synthesis and evaluation of naphthalene-2-carboxamides as reversal agents in MDR cancer. Bioorg Med Chem 2006;14:6022–6
  • Rajabi M, Khalilzadeh MA, Tavakolinia F, et al. Naphthalene-fused (α-alkoxycarbonyl)methylene-γ-butyrolactones: antiproliferative activity and binding to bovine serum albumin and DNA. DNA Cell Biol 2012;31:783–9
  • Medarde M, Maya ABS, Ferez-Melero C. Naphthalene combretastatin analogues: synthesis, cytotoxicity and antitubulin activity. J Enzyme Inhib Med Chem 2004;19:521–40
  • Reddy GR, Kuo CC, Tan UK, et al. Synthesis and structure–activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents. J Med Chem 2008;51:8163–7
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;16:55––63
  • van Engeland M, Nieland LJ, Ramaekers FC, et al. Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 1998;31:1–9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.