238
Views
11
CrossRef citations to date
0
Altmetric
Original Article

Distribution of CD4+CD25highFoxP3+ regulatory T-cells in umbilical cord blood

, , , , , , & show all
Pages 2058-2061 | Received 30 Dec 2011, Accepted 10 Feb 2012, Published online: 02 May 2012

References

  • Wing K, Larsson P, Sandström K, Lundin SB, Suri-Payer E, Rudin A. CD4+ CD25+ FOXP3+ regulatory T cells from human thymus and cord blood suppress antigen-specific T cell responses. Immunology 2005;115:516–525.
  • Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell 2008;133:775–787.
  • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057–1061.
  • Ozdemir C, Akdis M, Akdis CA. T regulatory cells and their counterparts: masters of immune regulation. Clin Exp Allergy 2009;39:626–639.
  • Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000;101:455–458.
  • Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol 2007;8:191–197.
  • Lo YM, Lo ES, Watson N, Noakes L, Sargent IL, Thilaganathan B, Wainscoat JS. Two-way cell traffic between mother and fetus: biologic and clinical implications. Blood 1996;88:4390–4395.
  • Takahata Y, Nomura A, Takada H, Ohga S, Furuno K, Hikino S, Nakayama H, et al. CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene. Exp Hematol 2004;32:622–629.
  • Liu J, Lluis A, Illi S, Layland L, Olek S, von Mutius E, Schaub B. T regulatory cells in cord blood–FOXP3 demethylation as reliable quantitative marker. PLoS ONE 2010;5:e13267.
  • Mahmud D, Nicolini B, van den Dries L, Mahmud N, Arpinati M, Rondelli D. Human CD4(+)CD25(+) Cells in Combination with CD34(+) Cells and thymoglobulin to prevent anti-hematopoietic stem cell t cell alloreactivity. Biol Blood Marrow Transplant 2011;17:61–68.
  • Hoffman R. Hematology: basic principles and practice. 5th ed. Philadelphia, PA: Churchill Livingstone/Elsevier; 2009. pp 2523.
  • Sakaguchi S, Miyara M, Costantino CM, Hafler DA. FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol 2010;10:490–500.
  • Mackroth MS, Malhotra I, Mungai P, Koech D, Muchiri E, King CL. Human cord blood CD4+CD25hi regulatory T cells suppress prenatally acquired T cell responses to Plasmodium falciparum antigens. J Immunol 2011;186:2780–2791.
  • Chng WJ, Tan GB, Kuperan P. Establishment of adult peripheral blood lymphocyte subset reference range for an Asian population by single-platform flow cytometry: influence of age, sex, and race and comparison with other published studies. Clin Diagn Lab Immunol 2004;11:168–173.
  • Comans-Bitter WM, de Groot R, van den Beemd R, Neijens HJ, Hop WC, Groeneveld K, Hooijkaas H, van Dongen JJ. Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations. J Pediatr 1997;130:388–393.
  • Horowitz GL and Clinical and Laboratory Standards Institute. eds. Defining, establishing, and verifying reference intervals in the clinical laboratory: approved guideline. 3rd ed. Wayne, PA: Clinical and Laboratory Standards Institute; 2008. pp 61.
  • Moon HW, Kim BH, Park CM, Hur M, Yun YM, Kim SY, Lee MH. CD4+CD25highFoxP3+ regulatory T-cells in hematologic diseases. Korean J Lab Med 2011;31:231–237.
  • Reed AH, Henry RJ, Mason WB. Influence of statistical method used on the resulting estimate of normal range. Clin Chem 1971;17:275–284.
  • Szczawinska-Poplonyk A. An overlapping syndrome of allergy and immune deficiency in children. J Allergy (Cairo) 2012;2012:658279.
  • Pandiyan P, Zheng L, Ishihara S, Reed J, Lenardo MJ. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat Immunol 2007;8:1353–1362.
  • Shpall EJ, Bollard CM, Brunstein C. Novel cord blood transplant therapies. Biol Blood Marrow Transplant 2011;17:S39–S45.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.