Male gender promotes an increased inflammatory response to lipopolysaccharide in umbilical vein blood

References

• Ingemarsson I. Gender aspects of preterm birth. BJOG 2003;110 Suppl 20:34–38.
   PubMedGoogle Scholar
• Cooperstock M, Campbell J. Excess males in preterm birth: interactions with gestational age, race, and multiple birth. Obstet Gynecol 1996;88:189–193.
   PubMed Web of Science ®Google Scholar
• Hassold T, Quillen SD, Yamane JA. Sex ratio in spontaneous abortions. Ann Hum Genet 1983;47:39–47.
   PubMed Web of Science ®Google Scholar
• Wichmann MW, Inthorn D, Andress HJ, Schildberg FW. Incidence and mortality of severe sepsis in surgical intensive care patients: the influence of patient gender on disease process and outcome. Intensive Care Med 2000;26:167–172.
   PubMed Web of Science ®Google Scholar
• Schröder J, Kahlke V, Staubach KH, Zabel P, Stüber F. Gender differences in human sepsis. Arch Surg 1998;133:1200–1205.
   PubMed Web of Science ®Google Scholar
• Majetschak M, Christensen B, Obertacke U, Waydhas C, Schindler AE, Nast-Kolb D, Schade FU. Sex differences in posttraumatic cytokine release of endotoxin-stimulated whole blood: relationship to the development of severe sepsis. J Trauma 2000;48:832–9; discussion 839.
   PubMedGoogle Scholar
• Dembic Z. Beginning of the end of (understanding) the immune response. Scand J Immunol 2008;68:381–382.
   PubMedGoogle Scholar
• Christiaens I, Zaragoza DB, Guilbert L, Robertson SA, Mitchell BF, Olson DM. Inflammatory processes in preterm and term parturition. J Reprod Immunol 2008;79:50–57.
   PubMed Web of Science ®Google Scholar
• Romero R, Gomez R, Ghezzi F, Yoon BH, Mazor M, Edwin SS, Berry SM. A fetal systemic inflammatory response is followed by the spontaneous onset of preterm parturition. Am J Obstet Gynecol 1998;179:186–193.
   PubMed Web of Science ®Google Scholar
• Ghidini A, Salafia CM. Gender differences of placental dysfunction in severe prematurity. BJOG 2005;112:140–144.
   PubMed Web of Science ®Google Scholar
• Romero R, Gomez R, Galasso M, Mazor M, Berry SM, Quintero RA, Cotton DB. The natural interleukin-1 receptor antagonist in the fetal, maternal, and amniotic fluid compartments: the effect of gestational age, fetal gender, and intrauterine infection. Am J Obstet Gynecol 1994;171:912–921.
   PubMed Web of Science ®Google Scholar
• Menon R, Merialdi M, Lombardi SJ, Fortunato SJ. Differences in the placental membrane cytokine response: a possible explanation for the racial disparity in preterm birth. Am J Reprod Immunol 2006;56:112–118.
   PubMed Web of Science ®Google Scholar
• Dembinski J, Behrendt D, Reinsberg J, Bartmann P. Endotoxin-stimulated production of IL-6 and IL-8 is increased in short-term cultures of whole blood from healthy term neonates. Cytokine 2002;18:116–119.
   PubMedGoogle Scholar
• Khanjani S, Kandola MK, Lindstrom TM, Sooranna SR, Melchionda M, Lee YS, Terzidou V, et al. NF-?B regulates a cassette of immune/inflammatory genes in human pregnant myometrium at term. J Cell Mol Med 2011;15:809–824.
   PubMedGoogle Scholar
• Kamel RM. The onset of human parturition. Arch Gynecol Obstet 2010;281:975–982.
   PubMed Web of Science ®Google Scholar
• Gargano JW, Holzman C, Senagore P, Thorsen P, Skogstrand K, Hougaard DM, Rahbar MH, Chung H. Mid-pregnancy circulating cytokine levels, histologic chorioamnionitis and spontaneous preterm birth. J Reprod Immunol 2008;79:100–110.
   PubMed Web of Science ®Google Scholar
• Fukuda H, Masuzaki H, Ishimaru T. Interleukin-6 and interleukin-1 receptor antagonist in amniotic fluid and cord blood in patients with pre-term, premature rupture of the membranes. Int J Gynaecol Obstet 2002;77:123–129.
   PubMed Web of Science ®Google Scholar
• Romero R, Mazor M, Tartakovsky B. Systemic administration of interleukin-1 induces preterm parturition in mice. Am J Obstet Gynecol 1991;165:969–971.
   PubMed Web of Science ®Google Scholar
• Ertan T, Keskek M, Kilic M, Gocmen E, Oguz H, Aksaray S, Koc M. Effects of gender difference in early cytokine levels in trauma patients. Bratisl Lek Listy 2007;108:128–132.
   PubMedGoogle Scholar
• Romero R, Tartakovsky B. The natural interleukin-1 receptor antagonist prevents interleukin-1-induced preterm delivery in mice. Am J Obstet Gynecol 1992;167:1041–1045.
   PubMed Web of Science ®Google Scholar
• Lucchi NW, Moore JM. LPS induces secretion of chemokines by human syncytiotrophoblast cells in a MAPK-dependent manner. J Reprod Immunol 2007;73:20–27.
   PubMedGoogle Scholar
• Beloosesky R, Gayle DA, Ross MG. Maternal N-acetylcysteine suppresses fetal inflammatory cytokine responses to maternal lipopolysaccharide. Am J Obstet Gynecol 2006;195:1053–1057.
   PubMed Web of Science ®Google Scholar
• Aulock SV, Deininger S, Draing C, Gueinzius K, Dehus O, Hermann C. Gender difference in cytokine secretion on immune stimulation with LPS and LTA. J Interferon Cytokine Res 2006;26:887–892.
   PubMed Web of Science ®Google Scholar
• Moxley G, Posthuma D, Carlson P, Estrada E, Han J, Benson LL, Neale MC. Sexual dimorphism in innate immunity. Arthritis Rheum 2002;46:250–258.
   PubMedGoogle Scholar