Vitamin D and neonatal immune function

References

• McKenna MJ. Differences in vitamin D status between countries in young adults and the elderly. Am J Med 1992;93:69–77
   PubMed Web of Science ®Google Scholar
• Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266–81
   PubMed Web of Science ®Google Scholar
• Mellanby E. An experimental investigation of rickets. Lancet 1919;1:407–12
   Google Scholar
• Hewison M. Vitamin D and innate immunity. Curr Opin Investig Drugs 2008;9:485–490
   PubMed Web of Science ®Google Scholar
• Braun AB, Gibbons FK, Litonjua AA, et al. Low serum 25-hydroxyvitamin D at critical care initiation is associated with increased mortality. Crit Care Med 2012;40:63–72
   PubMed Web of Science ®Google Scholar
• Arnson Y, Gringauz I, Itzhaky D, et al. Vitamin D deficiency is associated with poor outcomes and increased mortality in severely ill patients. QJM 2012;105:633–9
   PubMed Web of Science ®Google Scholar
• Zittermann A, Iodice S, Pilz S, et al. Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies. Am J Clin Nutr 2012;95:91–100
   PubMed Web of Science ®Google Scholar
• Braun A, Chang D, Mahadevappa K, et al. Association of low serum 25 hydroxyvitamin D levels and mortality in the critically ill. Crit Care Med 2011; 39:671–7
   PubMed Web of Science ®Google Scholar
• Masten AR. Sunlight in tuberculosis. Chest 1935;1:8–23
   Google Scholar
• White JH. Vitamin D signaling, infectious diseases, and regulation of innate immunity. Infect Immun 2008;76:3837–43
   PubMed Web of Science ®Google Scholar
• Alroy I, Towers TL, Freedman LP. Transcriptional repression of the interleukin-2 gene by vitamin D3: direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor. Mol Cell Biol 1995;15:5789–99
   PubMed Web of Science ®Google Scholar
• Ren S, Nguyen L, Wu S, et al. Alternative splicing of vitamin D-24-hydroxylase: a novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis. J Biol Chem 2005;280:20604–11
   PubMed Web of Science ®Google Scholar
• Dijkstra SH, van Beek A, Janssen JW, et al. High prevalence of vitamin D deficiency in newborn infants of high-risk mothers. Arch Dis Child 2007;92:750–3
   PubMed Web of Science ®Google Scholar
• Lee JM, Smith JR, Philipp BL, et al. Vitamin D deficiency in a healthy group of mothers and newborn infants. Clin Pediatr (Phila) 2007;46:42–4
   PubMed Web of Science ®Google Scholar
• Hollis BW, Pittard WB. Evaluation of the total fetomaternal vitamin D relationships at term: evidence for racial differences. J Clin Endocrinol Metab 1984;59:652–7
   PubMed Web of Science ®Google Scholar
• Nicolaidou P, Hatzistamatiou Z, Papadopoulou A, et al. Low vitamin D status in mother-newborn pairs in Greece. Calcif Tissue Int 2006;78:337–42
   PubMed Web of Science ®Google Scholar
• McCarthy R, McCallion N, Harrison G, et al. Relationship between vitamin D and alkaline phosphatase in very-low-birthweight infants. Arch Dis Child Fetal Neonatal Ed 2009;94:F77–8
   Google Scholar
• Walker VP, Zhang X, Rastegar I, et al. Cord blood vitamin D status impacts innate immune responses. J Clin Endocrinol Metab 2011;96:1835–43
   PubMed Web of Science ®Google Scholar
• Grant WB. Vitamin D supplementation of mother and infant could reduce risk of sepsis in premature infants. Early Hum Dev 2010;86:133
   PubMed Web of Science ®Google Scholar
• Nelson A, Hultenby K, Hell E, et al. Staphylococcus epidermidis isolated from newborn infants express pilus-like structures and are inhibited by the cathelicidin-derived antimicrobial peptide LL37. Pediatr Res 2009;66:174–8
   PubMedGoogle Scholar
• Moller S, Laigaard F, Olgaard K, et al. Effect of 1,25-dihydroxy-vitamin D3 in experimental sepsis. Int J Med Sci 2007;4:190–5
   PubMedGoogle Scholar
• Jeng L, Yamshchikov AV, Judd SE, et al. Alterations in vitamin D status and anti-microbial peptide levels in patients in the intensive care unit with sepsis. J Transl Med 2009;7:28
   PubMed Web of Science ®Google Scholar
• Muhe L, Lulseged S, Mason KE, et al. Case-control study of the role of nutritional rickets in the risk of developing pneumonia in Ethiopian children. Lancet 1997;349:1801–4
   PubMed Web of Science ®Google Scholar
• Walker VP, Modlin RL. The vitamin D connection to pediatric infections and immune function. Pediatr Res 2009;65:106R–13R
   PubMed Web of Science ®Google Scholar
• Ginde AA, Mansbach JM, Camargo CA Jr. Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med 2009;16:384–90
   Google Scholar
• Laaksi I, Ruohola JP, Tuohimaa P, et al. An association of serum vitamin D concentrations <40 nmol/L with acute respiratory tract infection in young Finnish men. Am J Clin Nutr 2007;86:714–7
   PubMed Web of Science ®Google Scholar
• McNally JD, Leis K, Matheson LA, et al. Vitamin D deficiency in young children with severe acute lower respiratory infection. Pediatr Pulmonol 2009;44:981–8
   PubMed Web of Science ®Google Scholar
• Tian M, Zhao DY, Wen GY, et al. The correlation factor about respiratory syncytial virus bronchiolitis and post-bronchiolitis wheezing in infant. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2009;23:371–4
   PubMedGoogle Scholar
• Camargo CA Jr, Ingham T, Wickens K, et al. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics 2011;127:e180–7
   PubMed Web of Science ®Google Scholar
• Bagnoli F, Casucci M, Rossetti A, et al. Vitamin D as a drug. J Matern Fetal Neonatal Med 2011;24:7–11
   PubMed Web of Science ®Google Scholar
• Rothers J, Wright AL, Stern DA, et al. Cord blood 25-hydroxyvitamin D levels are associated with aeroallergen sensitization in children from Tucson, Arizona. J Allergy Clin Immunol 2011;128:1093–9. e1-5
   PubMed Web of Science ®Google Scholar
• Belderbos ME, Houben ML, Wilbrink B, et al. Cord blood vitamin D deficiency is associated with respiratory syncytial virus bronchiolitis. Pediatrics 2011;127:e1513–20
   PubMed Web of Science ®Google Scholar
• Chi A, Wildfire J, McLoughlin R, et al. Umbilical cord plasma 25-hydroxyvitamin D concentration and immune function at birth: the urban environment and childhood asthma study. Clin Exp Allergy 2011;41:842–50
   PubMed Web of Science ®Google Scholar
• Hansdottir S, Monick MM, Hinde SL, et al. Respiratory epithelial cells convert inactive vitamin D to its active form: potential effects on host defense. J Immunol 2008;181:7090–9
   PubMed Web of Science ®Google Scholar
• Hansdottir S, Monick MM, Lovan N, et al. Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. J Immunol 2010;184:965–74
   PubMed Web of Science ®Google Scholar
• Fleming DM, Elliot AJ. Epidemic influenza and vitamin D. Epidemiol Infect 2007;135:1091–2
   PubMed Web of Science ®Google Scholar
• Yim S, Dhawan P, Ragunath C, et al. Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3). J Cyst Fibros 2007;6:403–10
   PubMed Web of Science ®Google Scholar
• Williams C. On the use and administration of cod liver oil in pulmonary consumption. Lond J Med 1849;1:1–18
   Google Scholar
• Nnoaham KE, Clarke A. Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. Int J Epidemiol 2008;37:113–9
   PubMed Web of Science ®Google Scholar
• Roth DE, Jones AB, Prosser C, et al. Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood. J Infect Dis 2008;197:676–80
   PubMed Web of Science ®Google Scholar
• Roth DE, Soto G, Arenas F, et al. Association between vitamin D receptor gene polymorphisms and response to treatment of pulmonary tuberculosis. J Infect Dis 2004;190:920–7
   PubMed Web of Science ®Google Scholar
• Wilkinson RJ, Llewelyn M, Toossi Z, et al. Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. Lancet 2000;355:618–21
   PubMed Web of Science ®Google Scholar
• Villamor E. A potential role for vitamin D on HIV infection? Nutr Rev 2006;64:226–33
   PubMed Web of Science ®Google Scholar
• Bergman P, Walter-Jallow L, Broliden K, et al. The antimicrobial peptide LL-37 inhibits HIV-1 replication. Curr HIV Res 2007;5:410–5
   PubMed Web of Science ®Google Scholar
• Adkins B, Leclerc C, Marshall-Clarke S. Neonatal adaptive immunity comes of age. Nature Rev Immunol 2004;4:553–64
   PubMed Web of Science ®Google Scholar
• Firth MA, Shewen PE, Hodgins DC. Passive and active components of neonatal innate immune defenses. Anim. Health Res Rev 2005;6:143–58
   PubMedGoogle Scholar
• Fusunyan RD, Nanthakumar NN, Baldeon ME, et al. Evidence for an innate immune response in the immature human intestine: toll-like receptors on fetal enterocytes. Pediatr Res 2001;49:589–93
   PubMed Web of Science ®Google Scholar
• Harju K, Glumoff V, Hallman M. Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice. Pediatr Res 2001;49:81–3
   PubMed Web of Science ®Google Scholar
• Levy O, Zarember KA, Roy RM, et al. Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848. J Immunol 2004;173:4627–34
   PubMed Web of Science ®Google Scholar
• Sadeghi K, Berger A, Langgartner M, et al. Immaturity of infection control in preterm and term newborns is associated with impaired toll-like receptor signaling. J Infect Dis 2007;195:296–302
   PubMed Web of Science ®Google Scholar
• Clairmont A, Tessman D, Stock A, et al. Induction of gap junctional intercellular communication by vitamin D in human skin fibroblasts is dependent on the nuclear vitamin D receptor. Carcinogenesis 1996;17:1389–91
   PubMed Web of Science ®Google Scholar
• Gniadecki R, Gajkowska B, Hansen M. 1,25-Dihydroxyvitamin D3 stimulates the assembly of adherens junctions in keratinocytes: involvement of protein kinase C. Endocrinology 1997;138:2241–8
   PubMed Web of Science ®Google Scholar
• Pálmer HG, González-Sancho JM, Espada J, et al. Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol 2001;154:369–87
   PubMed Web of Science ®Google Scholar
• Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 2002;415:389–95
   PubMed Web of Science ®Google Scholar
• Liu PT, Stenger S, Tang DH, et al. Cutting edge: vitamin d-mediated human antimicrobial activity against mycobacterium tuberculosis is dependent on the induction of cathelicidin. J Immunol 2007;179:2060–3
   PubMed Web of Science ®Google Scholar
• Schauber J, Dorschner RA, Coda AB, et al. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest 2007;117:803–11
   PubMed Web of Science ®Google Scholar
• Misawa Y, Baba A, Ito S, et al. Vitamin D(3) induces expression of human cathelicidin antimicrobial peptide 18 in newborns. Int J Hematol 2009;90:561–70
   PubMedGoogle Scholar
• Liu PT, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006;311:1770–3
   PubMed Web of Science ®Google Scholar
• Gombart AF, Borregaard N, Koeffler HP. Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3. FASEB J 2005;19:1067–77
   PubMed Web of Science ®Google Scholar
• Gerry K. Schwalfenberg: a review of the critical role of vitamin D in the functioning of the immune system and the clinical implications of vitamin D deficiency. Mol Nutr Food Res 2010;54:1–13
   Google Scholar
• Mandic Havelka A, Yektaei-Karin E, Hultenby K, et al. Maternal plasma level of antimicrobial peptide LL37 is a major determinant factor of neonatal plasma LL37 level. Acta Paediatr 2010;99:836–41
   PubMedGoogle Scholar
• Liu N, Kaplan AT, Low J, et al. Vitamin D induces innate antibacterial responses in human trophoblasts via an intracrine pathway. Biol Reprod 2009;80:398–406
   PubMed Web of Science ®Google Scholar
• Wang TT, Nestel FP, Bourdeau V, et al. Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol 2004;173:2909–12
   PubMed Web of Science ®Google Scholar
• Yuk JM, Shin DM, Lee HM, et al. Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin. Cell Host Microb 2009;6:231–43
   PubMed Web of Science ®Google Scholar
• Peric M, Koglin S, Ruzicka T, et al. Cathelicidins: multifunctional defense molecules of the skin. Dtsch Med Wochenschr 2009;134:35–8
   PubMed Web of Science ®Google Scholar
• Niyonsaba F, Nagaoka I, Ogawa H. Human defensins and cathelicidins in the skin: beyond direct antimicrobial properties. Crit Rev Immunol 2006;26:545–76
   PubMed Web of Science ®Google Scholar
• Otte JM, Zdebik AE, Brand S, et al. Effects of the cathelicidin LL-37 on intestinal epithelial barrier integrity. Regul Pept 2009;156:104–117
   PubMedGoogle Scholar
• Takahashi K, Nakayama Y, Horiuchi H, et al. Human neutrophils express messenger RNA of vitamin D receptor and respond to 1alpha,25-dihydroxyvitamin D3. Immunopharmacol Immunotoxicol 2002;24:335–47
   PubMed Web of Science ®Google Scholar
• Lorente F, Fontan G, Jara P, et al. Defective neutrophil motility in hypovitaminosis D rickets. Acta Paediatr Scand 1976;65:695–9
   PubMed Web of Science ®Google Scholar
• Schmidt HH, Seifert R, Bohme E. Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4. FEBS Lett 1989;244:357–60
   PubMed Web of Science ®Google Scholar
• Etzioni A, Hochberg Z, Pollak S, et al. Defective leukocyte fungicidal activity in end-organ resistance to 1,25-dihydroxyvitamin D. Pediatr Res 1989;25:276–9
   PubMed Web of Science ®Google Scholar
• Baeke F, Gysemans C, Korf H, et al. Vitamin D insufficiency: implications for the immune system. Pediatric Nephrol 2010;25:1597–606
   PubMed Web of Science ®Google Scholar
• Chen SF. 1 Alpha, 25-dihydroxyvitamin D3 decreased ICAM-1 and ELAM-1 expressions on pulmonary microvascular endothelial cells and neutrophil motivation. J Steroid Biochem Mol Biol 1995;52:67–70
   PubMedGoogle Scholar
• Kew RR, Fisher JA, Webster RO. Co-chemotactic effect of Gc-globulin (vitamin D binding protein) for C5a. Transient conversion into an active co-chemotaxin by neutrophils. J Immunol 1995;155:5369–74
   PubMed Web of Science ®Google Scholar
• DiMartino SJ, Shah AB, Trujillo G, et al. Elastase controls the binding of the vitamin D-binding protein (Gc-globulin) to neutrophils: a potential role in the regulation of C5a co-chemotactic activity. J Immunol 2001;166:2688–94
   PubMed Web of Science ®Google Scholar
• Shah AB, DiMartino SJ, Trujillo G, et al. Selective inhibition of the C5a chemotactic cofactor function of the vitamin D binding protein by 1,25(OH)2 vitamin D3. Mol Immunol 2006;43:1109–15
   PubMed Web of Science ®Google Scholar
• Do JE, Kwon SY, Park S, et al. Effects of vitamin D on expression of Toll-like receptors of monocytes from patients with Behcet's disease. Rheumatology (Oxford) 2008;47:840–8
   PubMed Web of Science ®Google Scholar
• Sadeghi K, Wessner B, Laggner U, et al. Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. Eur J Immunol 2006;36:361–70
   PubMed Web of Science ®Google Scholar
• Levy R, Malech HL. Effect of 1,25-dihydroxyvitamin D3, lipopolysaccharide, or lipoteichoic acid on the expression of NADPH oxidase components in cultured human monocytes. J Immunol 1991;147:3066–71
   PubMedGoogle Scholar
• Mariani E, Ravaglia G, Forti P, et al. Vitamin D, thyroid hormones and muscle mass influence natural killer (NK) innate immunity in healthy nonagenarians and centenarians. Clin Exp Immunol 1999;116:19–27
   PubMed Web of Science ®Google Scholar
• Merino F, Alvarez-Mon M, de la Hera A, et al. Regulation of natural killer cytotoxicity by 1,25-dihydroxyvitamin D3. Cell Immunol 1989;118:328–36
   PubMedGoogle Scholar
• Chen S, Sims GP, Chen XX, et al. Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation. J Immunol 2007;179:1634–47
   PubMed Web of Science ®Google Scholar
• Bhalla AK, Amento EP, Clemens TL, et al. Specific high-affinity receptors for 1,25-dihydroxyvitamin D3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes following activation. J Clin Endocrinol Metab 1983;57:1308–10
   PubMed Web of Science ®Google Scholar
• Provvedini DM, Tsoukas CD, Deftos LJ, et al. 1 Alpha,25-dihydroxyvitamin D3-binding macromolecules in human B lymphocytes: effects on immunoglobulin production. J Immunol 1986;136:2734–40
   PubMed Web of Science ®Google Scholar
• Lemire JM, Archer DC, Beck L, et al. Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions. J Nutr 1995;125:1704S–8S
   PubMed Web of Science ®Google Scholar
• Penna G, Adorini L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 2000;164:2405–11
   PubMed Web of Science ®Google Scholar
• Daniel C, Sartory NA, Zahn N, et al. Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile. J Pharmacol Exp Ther 2008;324:23–33
   PubMed Web of Science ®Google Scholar
• Penna G, Amuchastegui S, Giarratana N, et al. 1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells. J Immunol 2007;178:145–53
   PubMed Web of Science ®Google Scholar
• Boonstra A, Barrat FJ, Crain C, et al. 1Alpha,25-dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol 2001;167:4974–80
   PubMed Web of Science ®Google Scholar
• Nunn JD, Katz DR, Barker S, et al. Regulation of human tonsillar T-cell proliferation by the active metabolite of vitamin D3. Immunology 1986;59:479–84
   PubMedGoogle Scholar
• Sigmundsdottir H, Pan J, Debes GF, Alt C, et al. DCs metabolize sunlight-induced vitamin D3 to ‘program’ T cell attraction to the epidermal chemokine CCL27. Nat Immunol 2007;8:285–93
   PubMed Web of Science ®Google Scholar
• Spirig R, Potapova I, Shaw-Boden J, et al. TLR2 and TLR4 agonists induce production of the vasoactive peptide endothelin-1 by human dendritic cells. Mol Immunol 2009;46:3178–82
   PubMedGoogle Scholar
• Cantorna MT. Vitamin D and its role in immunology: multiple sclerosis, and inflammatory bowel disease. Prog Biophys Mol Biol 2006;92:60–4
   PubMed Web of Science ®Google Scholar
• Mathieu C, Gysemans C, Giulietti A, et al. Vitamin D and diabetes. Diabetologia 2005;48:1247–57
   PubMed Web of Science ®Google Scholar
• Stene LC, Joner G. Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study. Am J Clin Nutr 2003;78:1128–34
   PubMed Web of Science ®Google Scholar
• Marjamäki L, Niinistö S, Kenward MG, et al. Maternal intake of vitamin D during pregnancy and risk of advanced beta cell autoimmunity and type 1 diabetes in offspring. Diabetologia 2010;53:1599–607
   PubMed Web of Science ®Google Scholar
• McGrath JJ, Eyles DW, Pedersen CB, et al. Neonatal vitamin D status and risk of schizophrenia: a population-based case-control study. Arch Gen Psychiatry 2010;67:889–94
   PubMed Web of Science ®Google Scholar
• Eyles D, Burne T, McGrath J. Vitamin D in fetal brain development. Semin Cell Dev Biol 2011;22:629–36
   PubMed Web of Science ®Google Scholar
• White AJO, Holt BJ, Serralha M, et al. Maternal serum vitamin d levels during pregnancy and offspring neurocognitive development. Pediatrics 2012;129:485
   PubMedGoogle Scholar
• Hanwell HE, Banwell B. Assessment of evidence for a protective role of vitamin D in multiple sclerosis. Biochim Biophys Acta 2011;1812:202–12
   PubMed Web of Science ®Google Scholar
• Evans KN, Nguyen L, Chan J, et al. Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells. Biol Reprod 2006;75:816–22
   PubMed Web of Science ®Google Scholar
• Rebut-Bonneton C, Demignon J. Effects of 1,25-dihydroxyvitamin D3 on in vitro lymphocyte reactions: arguments for a role at the maternofetal interface. Gynecol Obstet Invest 1991;32:134–8
   PubMed Web of Science ®Google Scholar
• Fuller KE. Low birth-weight infants: the continuing ethnic disparity and the interaction of biology and environment. Ethn Dis 2000;10:432–45
   PubMedGoogle Scholar
• Cannell JJ. Autism and vitamin D. Med Hypotheses 2008;70:750–9
   PubMed Web of Science ®Google Scholar
• Fernell E, Barnevik-Olsson M, Bågenholm G, et al. Serum levels of 25-hydroxyvitamin D in mothers of Swedish and of Somali origin who have children with and without autism. Acta Paediatr 2010;99:743–7
   PubMed Web of Science ®Google Scholar
• Eyles DW. Vitamin D and autism: does skin colour modify risk? Acta Paediatr 2010;99:645–7
   PubMed Web of Science ®Google Scholar
• Humble MB, Gustafsson S, Bejerot S. Low serum levels of 25-hydroxyvitamin D (25-OHD) among psychiatric out-patients in Sweden: relations with season, age, ethnic origin and psychiatric diagnosis. J Steroid Biochem Mol Biol 2010;121:467-70
   PubMed Web of Science ®Google Scholar
• Kinney DK, Barch DH, Chayka B, et al. Environmental risk factors for autism: do they help cause de novo genetic mutations that contribute to the disorder? Med Hypotheses 2010;74:102–6
   PubMed Web of Science ®Google Scholar
• Food and Nutrition Board, Institute of Medicine. Report brief: dietary reference intakes for calcium and vitamin D. Washington (DC): National Academy Press; 2010. Available from: http://www.iom.edu/Reports/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Report-Brief.aspx [last accessed 22 Oct 2012]
   Google Scholar
• Hollis BW, Johnson D, Hulsey TC, et al. Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness. J Bone Miner Res 2011;26:2341–57
   PubMed Web of Science ®Google Scholar
• Hollis BW, Wagner CL. Vitamin D and pregnancy: skeletal effects, nonskeletal effects, and birth outcomes. Calcif Tissue Int 24 May 2012. [Epub ahead of print]
   Google Scholar
• Lekstrom-Himes JA, Dorman SE, Kopar P, et al. Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein e. J Exp Med 1999;189:1847–52
   PubMedGoogle Scholar
• Gombart AF, Shiohara M, Kwok SH, et al. Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein-e. Blood 2001;97:2561–7
   PubMedGoogle Scholar
• Tanaka Y, Klauck TM, Jubiz W. In vivo effects of 1,25-dihydroxyvitamin D3 and minerals on synthesis of leukotriene B4 and 5-hydroxyeicosatetraenoic acid by rat peritoneal neutrophils. Prostaglandins Leukot Essent Fatty Acids 1988;32:9–14
   PubMedGoogle Scholar
• Sadeghi K, Wessner B, Laggner U, et al. Vitamin D3 down regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. Eur J Immunol 2006;36:361–70
   PubMed Web of Science ®Google Scholar