References
- Nicholson JK, Lindon JC, Holmes E. ‘Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999;29:1181–9
- Fiehn O. Metabolomics – the link between genotypes and phenotypes. Plant Mol Biol 2002;48:155–71
- Mussap M, Antonucci R, Noto A. The role of metabolomics in neonatal and pediatric laboratory medicine. Clin Chim Acta 2013;426:127–38
- Issaq HJ, Van QN, Waybright TJ. Analytical and statistical approaches to metabolomics research. J Sep Sci 2009;32:2183–99
- World Health Statistics; 2013. Available from http://www.who.int/en/ [last accessed 10 Jul 2014]
- Yu Y, Clippinger AJ, Pierciey Jr FJ, Alwine JC. Viruses and metabolism: alterations of glucose and glutamine metabolism mediated by human cytomegalovirus. Adv Virus Res. 2011;80:49–67
- Morse SS, ed. The evolutionary biology of viruses. New York (NY): Raven Press; 1994
- Gandhi MK, Khanna R. Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments. Lancet Infect Dis 2004;4:725–38
- Lazzarotto T, Guerra B, Lanari M, et al. New advances in the diagnosis of congenital cytomegalovirus infection. J Clin Virol 2008;41:192–7
- Lazzarotto T, Guerra B, Gabrielli L, et al. Update on the prevention, diagnosis and management of cytomegalovirus infection during pregnancy. Clin Microbiol Infect 2011;17:1285–93
- Lanari M, Lazzarotto T, Venturi V, et al. Neonatal cytomegalovirus blood load and risk of sequelae in symptomatic and asymptomatic congenitally infected newborns. Pediatrics 2006;117:e76–83
- Fanos V, Locci E, Noto A, et al. Urinary metabolomics in newborns infected by human cytomegalovirus: a preliminary investigation. Early Human Develop 2013;89S1:S58–61
- Munger J, Bajad SU, Coller HA, et al. Dynamics of the cellular metabolome during human cytomegalovirus infection. PLoS Pathog 2006;2:e132
- Chen SL, Morgan TR. The natural history of hepatitis C virus (HCV) infection. Int J Med Sci 2006;3:47–52
- Zein NN. The epidemiology and natural history of hepatitis C virus infection. Cleve Clin J Med 2003;70:S2–6
- Ribeiro RM, Li H, Wang S, et al. Quantifying the diversification of hepatitis C virus (HCV) during primary infection: estimates of the in vivo mutation rate. PLoS Pathog 2012;8:e1002881
- Davis GL. Hepatitis C virus genotypes and quasispecies. Am J Med 1999;107:21S–5S
- Simmods P. Genetic diversity and evolution of hepatitis C virus – 15 years on. J Gen Virol 2004;85:3173–88
- Roe B, Kensicki E, Mohney R, Hall WW. Metabolomic profile of hepatitis C virus-infected hepatocytes. PLoS One 2011;6:e23641
- Sun H, Zhang A, Yan G, et al. Metabolomic analysis of key regulatory metabolites in hepatitis C virus-infected tree shrews. Mol Cell Proteomics 2013;12:710–19
- Wedemeyer H, Yurdaydın C, Dalekos GN, et al. Peginterferon plus adefovir versus either drug alone for hepatitis delta. N Engl J Med 2011;364:322–31
- Shimakawa Y, Yan HJ, Tsuchiya N, et al. Association of early age at establishment of chronic hepatitis B infection with persistent viral replication, liver cirrhosis and hepatocellular carcinoma: a systematic review. PLoS One 2013;8:e69430
- Zhang A, Sun H, Han Y, et al. Urinary metabolic biomarker and pathway study of hepatitis B virus infected patients based on UPLC-MS system. PLoS One 2013;8:e64381
- Yang Y, Yang S, Liang M, Qiu C. 1H NMR spectroscopy combined with principal component analysis for metabonomic study on serum of HBV patients. Acad J Second Military Med University 2010;31:288–91
- UNAIDS World AIDS day report 2011. Geneva: UNAIDS. Available from: http://www.unaids.org/en/media/unaids/contentassets/documents/unaidspublication/2011/jc2216_worldaidsday_report_2011_en.pdf [last accessed 10 Jul 2014]
- Hewer R, Vorster J, Steffens FE, Meyer D. Applying biofluid 1H NMR-based metabonomic techniques to distinguish between HIV-1 positive/AIDS patients on antiretroviral treatment and HIV-1 negative individuals. J Pharm Biomed Anal 2006;41:1442–6.
- Philippeos C, Steffens FE, Meyer D. Comparative 1H NMR-based metabonomic analysis of HIV-1 sera. J Biomol NMR 2009;44:127–37
- Maher D, Cysique LA, Brew BJ, Rae CD. Statistical integration of 1H NMR and MRS data from different biofluids and tissues enhances recovery of biological information from individuals with HIV-1 infection. J Proteome Res 2011;10:1737–45
- Munshi SU, Rewari BB, Bhavesh NS, Jameel S. Nuclear magnetic resonance based profiling of biofluids reveals metabolic dysregulation in HIV-infected persons and those on antiretroviral therapy. PLoS One 2013;8:e64298