Xylitol as a prophylaxis for acute otitis media: Systematic review

References

• American Academy of Pediatrics/American Academy of Family Physicians, Subcommittee on Management of Acute Otitis Media. 2004. Clinical practice guideline: diagnosis and management of acute otitis media. Pediatrics, 113, 1451–1465.
   PubMedGoogle Scholar
• Brook I., Gober A.E. 1997. Bacterial colonization of pacifiers of infants with acute otitis media. J Laryngol Otol, 111, 614–615.
   PubMedGoogle Scholar
• Burt B.A. 2006. The use of sorbitol- and xylitol-sweetened chewing gum in caries control. J Am Dent Assoc, 137, 190–196.
   PubMed Web of Science ®Google Scholar
• Cantekin E.I. 1998. Aggressive and ineffective therapy for otitis media. Otorhinolaryngol Nova, 8, 136–147.
   Google Scholar
• Cook D.J., Sackett D.L., Spitzer W.O. 1995. Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam Consultation on Meta-Analysis. J Clin Epidemiol, 48, 167–171.
   PubMed Web of Science ®Google Scholar
• Daly K.A., Rovers M.M., Hoffman H.J., Uhari M., Casselbrant M.L. . 2005. Recent advances in otitis media. 1. Epidemiology, natural history, and risk factors. Ann Otol Rhinol Laryngol Suppl, 194, 8–15.
   PubMedGoogle Scholar
• Grady D., Hearst N. 2007. Utilizing existing databases. S.B. Hulley, S.R. Cummings, W.S. Browner, D.G. Grady, T.B. Newman. Designing Clinical Research. Philadelphia: Lippincott, Williams, & Wilkins, 207–221.
   Google Scholar
• Godhim L.M.A., Suhonen J.T., Antila M.K., Sih T.M. 2005. Xylitol release pacifier in the prevention of otitis media. D.J. Lim, C.D. Bluestone, M.T. Casselbrant. Proceedings of the Eighth International Symposium on Recent Advances in Otitis Media. Ontario Canada: BC Decker, 143–145.
   Google Scholar
• Hautalahti O., Renko M., Tapiainen T., Kontiokari T., Pokka T. . 2007. Failure of xylitol given three times a day for preventing acute otitis media. Pediatr Infect Dis J, 26, 423–427.
   PubMedGoogle Scholar
• Howick J. 2009. Oxford Centre for Evidence-based Medicine Levels of Evidence. Available from: http://www.cebm.net/index.aspx?o=1025. Accessed: February 18, 2009.
   Google Scholar
• Isokangas P., Söderling E., Pienihäkkinen K., Alanen P. 2000. Occurrence of dental decay in children after maternal consumption of xylitol chewing gum, a follow-up from 0 to 5 years of age. J Dent Res, 79, 1885–1889.
   PubMedGoogle Scholar
• Kadhim A.L., Spilsbury K., Semmens J.B., Coates H.L., Lannigan F.J. 2007. Adenoidectomy for middleear effusion: a study of 50 000 children over 24 years. Laryngoscope, 117, 427–433.
   PubMedGoogle Scholar
• Klein J.O. 1994. Otitis media. Clin Infect Dis, 19, Suppl. 1, 823–833.
   PubMedGoogle Scholar
• Mäkinen K.K., Bennett C.A., Hujoel P., Isokangas P.J., Isotupa K.P. . 1995. Xylitol chewing gums and caries rates: A 40-month cohort study. J Dent Res, 74, 1904–1913.
   PubMed Web of Science ®Google Scholar
• Meropol S.B. 2008. Valuing reduced antibiotic use for pediatric acute otitis media. Pediatrics, 121, 669–673.
   PubMedGoogle Scholar
• Milgrom P., Rothen M., Milgrom L. 2006. Developing public health interventions with xylitol for the US and US-associated territories and states. Suom Hammaslaakarilehti, 13, 2–11.
   PubMedGoogle Scholar
• Niemela M., Uhari M., Moättoänen M. 1995. A pacifier increases the risk of recurrent acute otitis media in children in daycare centers. Pediatrics, 96, 884–888.
   PubMed Web of Science ®Google Scholar
• Niemela M., Pihakari O., Pokka T., Uhari M. 2000. Pacifier as a risk factor for acute otitis media: A randomized, controlled trial of parental counseling. Pediatrics, 106, 483–488.
   PubMedGoogle Scholar
• Paradise J.L. 1997. Short-course antimicrobial treatment for acute otitis media: not best for infants and young children. JAMA, 278, 1640–1642.
   PubMedGoogle Scholar
• Paradise J.L., Bluestone C.D., Colborn D.K., Bernard B.S., Smith C.G. . 1999. Adenoidectomy and adenotonsillectomy for recurrent acute otitis media: parallel randomized clinical trials in children not previously treated with tympanostomy tubes. JAMA, 282, 945–953.
   PubMed Web of Science ®Google Scholar
• Review Manager 5. 2010. Available from: http://ww.wcc-ims.net/revman. Accessed: March 5, 2010.
   Google Scholar
• Rosenfeld R.M., Goldsmith A.J., Tetlus L., Balzano A. 1997. Quality of life for children with otitis media. Arch Otolaryngol Head Neck Surg, 123, 1049–1054.
   PubMedGoogle Scholar
• Söderling E., Isokangas P., Pienihäkkinen K., Tenovuo J., Alanen P. 2001. Influence of maternal xylitol consumption on mother-child transmission of mutans streptococci: 6-year follow-up. Caries Res, 35, 173–177.
   PubMedGoogle Scholar
• Syrjänen R.K., Auranen K.J., Leino T.M., Kilpi T.M., Mäkelä P.H. 2005. Pneumococcal acute otitis media in relation to pneumococcal nasopharyngeal carriage. Pediatr Infect Dis J, 24, 801–806.
   PubMed Web of Science ®Google Scholar
• Tapiainen T., Luotonen L., Kontiokari T., Renko M., Uhari M. 2002. Xylitol administered only during respiratory infections failed to prevent acute otitis media. Pediatrics, 109, e19.
   PubMedGoogle Scholar
• Thorild I., Lindau B., Twetman S. 2006. Caries in 4-year-old children after maternal chewing of gums containing combinations of xylitol, sorbitol, chlorhexidine, and fluoride. Euro Arch Paediatr Dent, 11 7(4), 241–245.
   Google Scholar
• Uhari M., Kontiokari T., Koskela M., Niemela M. 1996. Xylitol chewing gum in prevention of acute otitis media: Double blind randomized trial. BMJ, 313, 1180–1184.
   PubMed Web of Science ®Google Scholar
• Uhari M., Kontiokari T., Niemela M. 1998. A novel use of xylitol sugar in preventing acute otitis media. Pediatrics, 102, 879–884.
   PubMed Web of Science ®Google Scholar
• Vergison A., Dagan R., Arguedas A., Bonhoeffer J., Cohen R. . 2010. Otitis media and its consequences: Beyond the earache. Lancet Infect Dis, 10, 195–203.
   PubMed Web of Science ®Google Scholar
• Vernacchio L., Vezina R.M., Mitchell A.A. 2007. Management of acute otitis media by primary care physicians: trends since the release of the 2004 American Academy of Pediatrics/American Academy of Family Physicians clinical practice guideline. Pediatrics, 120, 281–287.
   PubMed Web of Science ®Google Scholar
• Vouloumanou E.K., Karageorgopoulos D.E., Karantzi M.S., Kapaskelis A.M., Falagas M.E. 2009. Antibiotics versus placebo or watchful waiting for acute otitis media: A meta-analysis of randomized controlled trial. J Antimicrob Chemother, 64, 16–24.
   PubMed Web of Science ®Google Scholar
• Winskel H. 2006. The effects of an early history of otitis media on children's language and literacy skill development. Br J Educ Psychol, 76, 727–744.
   PubMed Web of Science ®Google Scholar