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Research Articles

Biochemical and immunological basis of silymarin effect, a milk thistle (Silybum marianum) against ethanol-induced oxidative damage

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Pages 409-413 | Received 25 Nov 2011, Accepted 03 Mar 2012, Published online: 04 Apr 2012

References

  • Aldo-Benson M, Pratt L, Hardwick J. 1992. Alcohol can inhibit effect of IL-4 on activated murine B cells. Immunol Res 11:117–124.
  • Ambadath V, Venu RG, Madambath I. 2010. Comparative study of the efficacy of ascorbic acid, quercetin, and thiamine for reversing ethanol-induced toxicity. J Med Food 13:1485–1489.
  • Arteel GE. 2003. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 124:778–790.
  • Bardag-Gorce F, French BA, Li J, Riley NE, Yuan QX, Valinluck V, Fu P, Ingelman-Sundberg M, Yoon S, French SW. 2002. The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats. Gastroenterology 123:325–335.
  • Bird GL, Sheron N, Goka AK, Alexander GJ, Williams RS. 1990. Increased plasma tumor necrosis factor in severe alcoholic hepatitis. Ann Intern Med 112:917–920.
  • Crews FT, Bechara R, Brown LA, Guidot DM, Mandrekar P, Oak S, Qin L, Szabo G, Wheeler M, Zou J. 2006. Cytokines and alcohol. Alcohol Clin Exp Res 30:720–730.
  • Das SK, Vasudevan DM. 2005. Effect of ethanol on liver antioxidant defense systems: a dose dependent study. Indian J Clin Biochem 20:80–84.
  • Das SK, Balakrishnan V, Vasudevan DM. 2006. Alcohol: its health and social impact in India. Natl Med J India 19:94–99.
  • Das SK, Vasudevan DM. 2006. Modulation of lecithin activity by vitamin-B complex to treat long term consumption of ethanol induced oxidative stress in liver. Indian J Exp Biol 44:791–801.
  • Das SK, Vasudevan DM. 2007. Alcohol-induced oxidative stress. Life Sci 81:177–187.
  • Das SK, Mukherjee S, Vasudevan DM. 2008. Potential uses of milk thistle. Natural Product Radiance 7:182–192.
  • Das SK, Varadhan S, Gupta G, Mukherjee S, Dhanya L, Rao DN, Vasudevan DM. 2009. Time-dependent effects of ethanol on blood oxidative stress parameters and cytokines. Indian J Biochem Biophys 46:116–121.
  • Das SK, Mukherjee S, Gupta G, Rao DN, Vasudevan DM. 2010. Protective effect of resveratrol and vitamin E against ethanol-induced oxidative damage in mice: biochemical and immunological basis. Indian J Biochem Biophys 47:32–37.
  • Diehl AM. 1998. Alcoholic liver disease. Clin Liver Dis 2:103–118.
  • Donnini S, Ziche M. 2002. Constitutive and inducible nitric oxide synthase: role in angiogenesis. Antioxid Redox Signal 4:817–823.
  • Ellman GL. 1959. Tissue sulfhydryl groups. Arch Biochem Biophys 82:70–77.
  • El-Taukhy MA, Salama SM, Abou-Shousha SA, Ismail SS, Saleh M. 2006. Effects of chronic ethanol and vitamin C administration on production of tumor necrosis factor-α and interleukin-6 in rats. Egypt J Immunol 13:1–10.
  • Felver ME, Mezey E, McGuire M, Mitchell MC, Herlong HF, Veech GA, Veech RL. 1990. Plasma tumor necrosis factor α predicts decreased long-term survival in severe alcoholic hepatitis. Alcohol Clin Exp Res 14:255–259.
  • Flora K, Hahn M, Rosen H, Benner K. 1998. Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol 93:139–143.
  • Goldberg MD. Spooner JR. (1983). Glutathione reductase. In: Bergmayer HU, Bergmayer J, Grabi M, eds. Methods of Enzymatic Analysis. Vol. III. 3rd edn. Florida: Academic Press Inc, 258–265.
  • Habig WH, Pabst MJ, Jakoby WB. 1974. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130–7139.
  • Lieber CS. 1993. Biochemical factors in alcoholic liver disease. Semin Liver Dis 13:136–153.
  • Loguercio C, Festi D. 2011. Silybin and the liver: from basic research to clinical practice. World J Gastroenterol 17:2288–2301.
  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275.
  • Maeng HG, Lim H, Jeong YJ, Woo A, Kang JS, Lee WJ, Hwang YI. 2009. Vitamin C enters mouse T cells as dehydroascorbic acidin vitroand does not recapitulate in vivovitamin C effects. Immunobiology 214:311–320.
  • Marklund S, Marklund G. 1974. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47:469–474.
  • Morazzoni P, Bombardelli E. 1995. Silybum marianum (Carduus marianus). Fitoterapia 56:3–42.
  • Mukherjee S, Das SK, Vasudevan DM. 2007. Effects of ethanol consumption on different organs-a brief overview. Asian J Biochem 2:386–394.
  • Paglia DE, Valentine WN. 1967. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70:158–169.
  • Rockey DC, Shah V. 2004. Nitric oxide biology and the liver: report of an AASLD research workshop. Hepatology 39:250–257.
  • Sergent O, Griffon B, Cillard P, Cillard J. 2001. [Alcohol and oxidative stress]. Pathol Biol 49:689–695.
  • Sinnhuber RO, Yu TC, Yu TC. 1958. Characterization of the red pigment formed in the thiobarbituric acid determination of oxidative rancidity. Food Res 23:626–630.
  • Suresh MV, Sreeranjit Kumar CV, Lal JJ, Indira M. 1999. Impact of massive ascorbic acid supplementation on alcohol induced oxidative stress in guinea pigs. Toxicol Lett 104:221–229.
  • Tilg H, Diehl AM. 2000. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 343:1467–1476.
  • Trappoliere M, Caligiuri A, Schmid M, Bertolani C, Failli P, Vizzutti F, Novo E, di Manzano C, Marra F, Loguercio C, Pinzani M. 2009. Silybin, a component of sylimarin, exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells. J Hepatol 50:1102–1111.
  • Tsukamoto H, Lu SC. 2001. Current concepts in the pathogenesis of alcoholic liver injury. FASEB J 15:1335–1349.
  • Valenzuela A, Aspillaga M, Vial S, Guerra R. 1989. Selectivity of silymarin on the increase of the glutathione content in different tissues of the rat. Planta Med 55:420–422.
  • Valenzuela A, Garrido A. 1994. Biochemical bases of the pharmacological action of the flavonoid silymarin and of its structural isomer silibinin. Biol Res 27:105–112.
  • Videla LA, Valenzuela A. 1982. Alcohol ingestion, liver glutathione and lipoperoxidation: metabolic interrelations and pathological implications. Life Sci 31:2395–2407.
  • Wu D, Cederbaum AI. 2003. Alcohol, oxidative stress, and free radical damage. Alcohol Res Health 27:277–284.
  • Yan JJ, Jung JS, Hong YJ, Moon YS, Suh HW, Kim YH, Yun-Choi HS, Song DK. 2004. Protective effect of protocatechuic acid isopropyl ester against murine models of sepsis: inhibition of TNF-α and nitric oxide production and augmentation of IL-10. Biol Pharm Bull 27:2024–2027.

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