High hydrostatic pressure treatment generates inactivated mammalian tumor cells with immunogeneic features

References

• Aertsen, A., Meersman, F., Hendrickx, M. E., Vogel, R. F., and Michiels, C. W. 2009. Biotechnology under high pressure: Applications and implications. Trends Biotechnol. 27:434–441.
   PubMed Web of Science ®Google Scholar
• Amato, R. J. 2003. Vaccine therapy for renal cell carcinoma. Rev. Urol. 5:65–71.
   PubMedGoogle Scholar
• Apetoh, L., Tesniere, A., Ghiringhelli, F., Kroemer, G., and Zitvogel, L. 2008. Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anti-cancer therapies. Cancer Res. 68:4026–4030.
   PubMed Web of Science ®Google Scholar
• Apte, R. N., and Voronov, E. 2008. Is interleukin-1 a good or bad ‘guy’ in tumor immunobiology and immunotherapy? Immunol. Rev. 222:222–241.
   PubMed Web of Science ®Google Scholar
• Balny, C. 1999. High-pressure enzyme kinetics. In Advances in High-Pressure Bioscience and Biotechnology (Ludwig, H., Ed.), Berlin: Springer Verlag, pp. 261–266.
   Google Scholar
• Balny, C., Hayashi, R., Heremans, K., and Masson, P. (Eds.) 1992. High-Pressure and Biotechnology, Montrouge: Editions John Libbey Eurotext Ltd.
   Google Scholar
• Balny, C., Masson, P., and Heremans, K. 2002. High-pressure effects on biological macromolecules: From structural changes to alteration of cellular processes. Biochim. Biophys. Acta 1595:3–10.
   PubMed Web of Science ®Google Scholar
• Bocchia, M., Bront, V., Colombo, M. P., Dd Vincentiis, A., Di Nicola, M., Forni, G., Lanata, L., Lemoli, R. M., Massaia, M., Rondelli, D., Zanon, P., and Tura, S. 2000. Anti-tumor vaccination: Where we stand. Haematologica 85:1172–1206.
   PubMed Web of Science ®Google Scholar
• Boonyaratanakornkit, B. B., Park, C. B., and Clark, D. S. 2002. Pressure effects on intra- and intermolecular interactions within proteins. Biochim. Biophys. Acta 1595:235–249.
   PubMed Web of Science ®Google Scholar
• Cheftel, J. C. 1992. Effects of high hydrostatic pressure on food constituents: An overview. In High-Pressure and Biotechnology (Balny, C., Hayashi, R., Heremans, K., and Masson, P., Eds.), Montrouge: INSERM/John Libbey Eurotext Ltd., pp. 195–209.
   Google Scholar
• Chen, X., Chang, C. H., and Goldenberg, D. M. 2009. Novel strategies for improved cancer vaccines. Expert Rev. Vaccines 8:567–576.
   PubMed Web of Science ®Google Scholar
• Copier, J., Ward, S., and Dalgleish, A. 2007. Cell based cancer vaccines: Regulatory and commercial development. Vaccine 25(S2):B35–46.
   Google Scholar
• De Gruijl, T. D., Van den Eertwegh, A. J., Pinedo, H. M., and Scheper, R. J. 2008. Whole-cell cancer vaccination: From autologous to allogeneic tumor- and dendritic cell-based vaccines. Cancer Immunol. Immunother. 57:1569–1577.
   PubMed Web of Science ®Google Scholar
• Diehl, P., Schauwecker, J., Mittelmeier, W., and Schmitt, M. 2008. High hydrostatic pressure, a novel approach in orthopedic surgical oncology to disinfect bone, tendons and cartilage. Anticancer Res. 28:3877–3883.
   PubMed Web of Science ®Google Scholar
• Diehl, P., Schmitt, M., Bluemelhuber, G., Frey, B., Van Laak, S., Fischer, S., Muehlenweg, B., Meyer-Pittroff, R., Gollwitzer, H., and Mittelmeier, W. 2003. Induction of tumor cell death by high hydrostatic pressure as a novel supporting technique in orthopedic surgery. Oncol. Rep. 10:1851–1855.
   PubMed Web of Science ®Google Scholar
• Dillman, R. O., Depriest, C., Deleon, C., Barth, N. M., Schwartzberg, L. S., Beutel, L. D., Schiltz, P. M., and Nayak, S. K. 2007. Patient-specific vaccines derived from autologous tumor cell lines as active specific immunotherapy: Results of exploratory Phase I/II trials in patients with metastatic melanoma. Cancer Biother. Radiopharm. 22:309–321.
   PubMed Web of Science ®Google Scholar
• Dubins, D. N., Lee, A., Macgregor, R. B., Jr., and Chalikian, T. V. 2001. On the stability of double stranded nucleic acids. J. Am. Chem. Soc. 123:9254–9259.
   PubMed Web of Science ®Google Scholar
• Elstein, K. H., and Zucker, R. M. 1994. Comparison of cellular and nuclear flow cytometric techniques for discriminating apoptotic sub-populations. Exp. Cell Res. 211:322–331.
   PubMed Web of Science ®Google Scholar
• Esche, C., Shurin, M. R., and Lotze, M. T. 1999. The use of dendritic cells for cancer vaccination. Curr. Opin. Mol. Ther. 1:72–81.
   PubMedGoogle Scholar
• Franz, S., Herrmann, K., Furnrohr, B. G., Sheriff, A., Frey, B., Gaipl, U. S., Voll, R. E., Kalden, J. R., Jack, H. M., and Herrmann, M. 2007. After shrinkage apoptotic cells expose internal membrane-derived epitopes on their plasma membranes. Cell Death Differ. 14:733–742.
   PubMed Web of Science ®Google Scholar
• Frey, B., Franz, S., Sheriff, A., Korn, A., Bluemelhuber, G., Gaipl, U. S., Voll, R. E., Meyer-Pittroff, R., and Herrmann, M. 2004. Hydrostatic pressure induced death of mammalian cells engages pathways related to apoptosis or necrosis. Cell. Mol. Biol. (Noisy-le-grand) 50:459–467.
   PubMed Web of Science ®Google Scholar
• Frey, B., Janko, C., Ebel, N., Meister, S., Schlucker, E., Meyer-Pittroff, R., Fietkau, R., Herrmann, M., and Gaipl, U. S. 2008. Cells under pressure - treatment of eukaryotic cells with high hydrostatic pressure, from physiologic aspects to pressure-induced cell death. Curr. Med. Chem. 15:2329–2336.
   PubMed Web of Science ®Google Scholar
• Frey, B., Schildkopf, P., Rodel, F., Weiss, E. M., Munoz, L. E., Herrmann, M., Fietkau, R., and Gaipl, U. S. 2009. Annexin A5 renders dead tumor cells immunogenic - implications for multimodal cancer therapies. J. Immunotoxicol. 6:209–216.
   PubMed Web of Science ®Google Scholar
• Gaipl, U. S., Beyer, T. D., Baumann, I., Voll, R. E., Stach, C. M., Heyder, P., Kalden, J. R., Manfredi, A., and Herrmann, M. 2003a. Exposure of anionic phospholipids serves as anti-inflammatory and immunosuppressive signal - implications for anti-phospholipid syndrome and systemic lupus erythematosus. Immunobiology 207:73–81.
   PubMed Web of Science ®Google Scholar
• Gaipl, U. S., Brunner, J., Beyer, T. D., Voll, R. E., Kalden, J. R., and Herrmann, M. 2003b. Disposal of dying cells: A balancing act between infection and autoimmunity. Arthritis Rheum. 48:6–11.
   PubMed Web of Science ®Google Scholar
• Gaipl, U. S., Munoz, L. E., Rodel, F., Pausch, F., Frey, B., Brachvogel, B., Von der Mark, K., and Poschl, E. 2007. Modulation of the immune system by dying cells and the phosphatidylserine-ligand Annexin A5. Autoimmunity 40:254–259.
   PubMed Web of Science ®Google Scholar
• Gallucci, S., and Matzinger, P. 2001. Danger signals: SOS to the immune system. Curr. Opin. Immunol. 13:114–119.
   PubMed Web of Science ®Google Scholar
• Hacker, G. 2000. The morphology of apoptosis. Cell Tissue Res. 301:5–17.
   PubMed Web of Science ®Google Scholar
• Heden, C. G. 1964. Effects of hydrostatic pressure on microbial systems. Bacteriol. Rev. 28:14–29.
   PubMedGoogle Scholar
• Heden, C. G., and Rupprecht, A. 1966. Semi-conductivity of dried oriented DNA. Acta Chem. Scand. 20:583–585.
   PubMedGoogle Scholar
• Jocham, D., Richter, A., Hoffmann, L., Iwig, K., Fahlenkamp, D., Zakrzewski, G., Schmitt, E., Dannenberg, T., Lehmacher, W., Von Wietersheim, J., and Doehn, C. 2004. Adjuvant autologous renal tumor cell vaccine and risk of tumor progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III randomized controlled trial. Lancet 363:594–599.
   PubMed Web of Science ®Google Scholar
• Kepp, O., Tesniere, A., Schlemmer, F., Michaud, M., Senovilla, L., Zitvogel, L., and Kroemer, G. 2009. Immunogenic cell death modalities and their impact on cancer treatment. Apoptosis 14:364–375.
   PubMed Web of Science ®Google Scholar
• Korn, A., Frey, B., Sheriff, A., Gaipl, U. S., Franz, S., Meyer-Pittroff, R., Bluemelhuberh, G., and Herrmann, M. 2004. High hydrostatic pressure-inactivated human tumor cells preserve their immunogenicity. Cell. Mol. Biol. (Noisy-le-grand) 50:469–477.
   PubMed Web of Science ®Google Scholar
• Kroemer, G., Galluzzi, L., Van den Abeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., El-Deiry, W. S., Golstein, P., Green, D. R., Hengartner, M., Knight, R. A., Kumar, S., Lipton, S. A., Malorni, W., Nunez, G., Peter, M. E., Tschopp, J., Yuan, J., Piacentini, M., Zhivotovsky, B., and Melino, G. 2009. Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ. 16:3–11.
   PubMed Web of Science ®Google Scholar
• Krysko, D. V., D’Herde, K., and Van den Abeele P. 2006. Clearance of apoptotic and necrotic cells and its immunological consequences. Apoptosis 11:1709–1726.
   PubMed Web of Science ®Google Scholar
• Macgregor, R. B. 2002. The interactions of nucleic acids at elevated hydrostatic pressure. Biochim. Biophys. Acta 1595:266–276.
   PubMed Web of Science ®Google Scholar
• Masson, P., Tonello, C., and Balny, C. 2001. High-pressure biotechnology in medicine and pharmaceutical science. J. Biomed. Biotechnol. 1:85–88.
   PubMedGoogle Scholar
• Matzinger, P. 1994. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12:991–1045.
   PubMed Web of Science ®Google Scholar
• Meyer-Pittroff, R., Behrendt, H., and Ring, J. 2006. Specific immunomodulation and therapy by means of high-pressure-treated allergens. High Pressure Res. 26:1–5.
   Google Scholar
• Moingeon, P., De Taisne, C., and Almond, J. 2002. Delivery technologies for human vaccines. Br. Med. Bull. 62:29–44.
   PubMed Web of Science ®Google Scholar
• Munoz, L. E., Frey, B., Pausch, F., Baum, W., Mueller, R. B., Brachvogel, B., Poschl, E., Rodel, F., Von der Mark, K., Herrmann, M., and Gaipl, U. S. 2007. The role of Annexin A5 in the modulation of the immune response against dying and dead cells. Curr. Med. Chem. 14:271–277.
   PubMed Web of Science ®Google Scholar
• Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Meth. 139:271–279.
   PubMed Web of Science ®Google Scholar
• Ott, O. J., Rodel, C., Weiss, C., Wittlinger, M., St., Krause, F., Dunst, J., Fietkau, R., and Sauer, R. 2009. Radiochemotherapy for bladder cancer. Clin. Oncol. (R. Coll. Radiol.) 21:557–565.
   PubMed Web of Science ®Google Scholar
• Patterson, M. F. 2005. Microbiology of pressure-treated foods. J. Appl. Microbiol. 98:1400–1409.
   PubMed Web of Science ®Google Scholar
• Paukovits, P., Himmler, G., and Loibner, H. 2004. Immunotherapy of malignant diseases -developments and prospects. Wien Med. Wochenschr. 154:235–241.
   PubMedGoogle Scholar
• Rosenberg, S. A., Yang, J. C., and Restifo, N. P. 2004. Cancer immunotherapy: Moving beyond current vaccines. Nat. Med. 10:909–915.
   PubMed Web of Science ®Google Scholar
• Rosenblatt, J., and Avigan, D. 2008. Cellular immunotherapy for multiple myeloma. Best Pract. Res. Clin. Haematol. 21:559–577.
   PubMed Web of Science ®Google Scholar
• San Martin, M. F., Barbosa-Canovas, G. V., and Swanson, B. G. 2002. Food processing by high hydrostatic pressure. Crit. Rev. Food Sci. Nutr. 42: 627–645.
   PubMed Web of Science ®Google Scholar
• Shearer, A. E., and Kniel, K. E. 2009. High hydrostatic pressure for development of vaccines. J. Food Prot. 72:1500–1508.
   PubMed Web of Science ®Google Scholar
• Smeller, L. 2002. Pressure-temperature phase diagrams of biomolecules. Biochim. Biophys. Acta 1595:11–29.
   PubMed Web of Science ®Google Scholar
• Stach, C. M., Turnay, X., Voll, R. E., Kern, P. M., Kolowos, W., Beyer, T. D., Kalden, J. R., and Herrmann, M. 2000. Treatment with Annexin V increases immunogenicity of apoptotic human T-cells in Balb/c mice. Cell Death Differ. 7:911–915.
   PubMed Web of Science ®Google Scholar
• Tesniere, A., Apetoh, L., Ghiringhelli, F., Joza, N., Panaretakis, T., Kepp, O., Schlemmer, F., Zitvogel, L., and Kroemer, G. 2008. Immunogenic cancer cell death: A key-lock paradigm. Curr. Opin. Immunol. 20:504–511.
   PubMed Web of Science ®Google Scholar
• Umansky, V., Malyguine, A., and Shurin, M. 2009. New perspectives in cancer immunotherapy and immunomonitoring. Future Oncol. 5:941–944.
   Google Scholar
• Vermes, I., Haanen, C., and Reutelingsperger, C. 2000. Flow cytometry of apoptotic cell death. J. Immunol. Meth. 243:167–190.
   PubMed Web of Science ®Google Scholar
• Vermes, I., Haanen, C., Steffens-Nakken, H., and Reutelingsperger, C. 1995. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein-labeled Annexin V. J. Immunol. Meth. 184:39–51.
   PubMed Web of Science ®Google Scholar
• Voll, R. E., Herrmann, M., Roth, E. A., Stach, C., Kalden, J. R., and Girkontaite, I. 1997. Immunosuppressive effects of apoptotic cells. Nature 390:350–351.
   PubMed Web of Science ®Google Scholar
• Winter, R. 2002. Synchrotron X-ray and neutron small-angle scattering of lyotropic lipid mesophases, model biomembranes, and proteins in solution at high pressure. Biochim. Biophys. Acta 1595:160–184.
   PubMed Web of Science ®Google Scholar
• Winter, R., and Dzwolak, W. 2004. Temperature-pressure configurational landscape of lipid bilayers and proteins. Cell. Mol. Biol. (Noisy-le-grand) 50:397–417.
   PubMed Web of Science ®Google Scholar
• Yannelli, J. R., Hirscowitz, E., and Wroblewski, J. M. 2003. Growth and functional reactivity of lymphocytes obtained from three anatomic compartments in patients with non-small-cell lung cancer (NSCLC). Cancer Biother. Radiopharm. 18:735–749.
   PubMed Web of Science ®Google Scholar
• Yannelli, J. R., and Wroblewski, J. M. 2004. On the road to a tumor cell vaccine: 20 years of cellular immunotherapy. Vaccine 23:97–113.
   PubMed Web of Science ®Google Scholar
• Yi, Q. 2003. Immunotherapy in multiple myeloma: Current strategies and future prospects. Expert Rev. Vaccines 2:391–398.
   PubMedGoogle Scholar