177
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Pre-treatment of BALB/c mice with a centrally acting serotonin antagonist (Cyproheptadine) reduces mortality from Boophone Disticha poisoning

, &
Pages 16-22 | Received 11 Sep 2012, Accepted 05 Nov 2012, Published online: 29 Nov 2012

References

  • World Health Organisation. Fact Sheets: Traditional Medicine (2008). Accessed at www.who.int/mediacentre/factsheets/fs134/en/ on 13/02/2010.
  • Tagwireyi D, Ball DE. ‘Muti’ poisoning in Zimbabwe. Trop Doct 2002; 32:41–42.
  • Tagwireyi D, Ball DE, Nhachi CFB. Traditional medicine poisoning in Zimbabwe: clinical presentation and management in adults. Hum Exp Toxicol 2002; 21:579–586.
  • Kadiri S, Arije A, Salako BL. Traditional herbal preparations and acute renal failure in South West Nigeria. Trop Doct 1999; 29: 244–246.
  • Gelfand M, Mavi S, Drummond RB, Ndemera B. The Traditional Medical Practitioner in Zimbabwe. Gweru: Mambo Press; 1985.
  • Eddleston M. Patterns and problems of deliberate self-poisoning in the developing world. Q J Med 2000; 93:715–731.
  • Foukaridis GN, Muntingh GL, Osuch E. Application of diode array detection for the identification of poisoning by traditional medicines. J Ethnopharmacol. 1994; 41:135–146.
  • Kasilo OM, Nhachi CF. The pattern of poisoning from traditional medicines in urban Zimbabwe. S Afr Med J 1992; 82:187–188.
  • Nhachi CF, Kasilo OM. The pattern of poisoning in urban Zimbabwe. J Appl Toxicol 1992; 12:435–438.
  • Onayade OA, Onayade AA, Sofowora A. Wound healing with plants: the African perspective. In: Hostettmann K, Chinyanganya F, Maillard, Wolfender JL, eds. Chemistry, Biological and Pharmacological Properties of African Medicinal Plants. Harare: University of Zimbabwe Press; 1996: 88.
  • Gadaga LL, Tagwireyi D, Dzangare J, Nhachi CFB. Acute oral toxicity and neurobehavioural toxicological effects of a hydroethanolic extract of Boophone disticha in rats. Hum Exp Toxicol 2011; 30:972–980.
  • Pederson ME, Szewczyk B, Stachowicz K, Wieronska J, Andersen J, Stafford GI, . Effects of South African traditional medicines in animal models for depression. J Ethnopharmacol 2008; 119:542–548.
  • Sandanger M, Neilsen ND, Stafford GI, van Staden J, Jager AK. Alkaloids from Boophane disticha with affinity to the serotonin transporter in the rat brain. J Ethanopharmacol 2005; 98:367–370.
  • van Wyk BE, van Oudtshoorn B, Gericke N. Medicinal Plants of Southern Africa. 1st ed. Pretoria: Briza Publications; 1997.
  • Sobiecki JF. A preliminary inventory of plants used for psychoactive purposes in Southern Africa healing traditions. Trans R Soc S Afr 2002; 57:1–24.
  • Laing RO. Three cases of poisoning by Boophane disticha. Cent Afr J Med 1979; 25:265–266.
  • Steenkamp PA. Chemical Analysis of Medicinal and Poisonous Plants of Forensic Importance in South Africa. Doctor of Philosophy Thesis. University of Johannesburg, 2005.
  • Watt JM, Breyer-Brandwjk MG. The Medicinal and Poisonous Plants of Southern and Eastern Africa. Edinburg and London: E and S Livingstone; 1962.
  • Munday J. Poisonous Plants in South Africa Gardens and Parks, a Field Guide. Craighall, Johannesburg: Delta books; 1988.
  • Hauth H, Stauffacher D. Die Alkaloidie von Buphane disticha (Lf) Herb. Helv Chim Acta 1961; 44:491–502.
  • McDaniel K, Moser V. Utility of a neurobehavioral screening battery for differentiating the effects of two pyrethroids, permethrins and cypermethrin. Neurotoxicol Teratol 1993; 15:71–83.
  • Nielsen N. Screening of indigenous plant from South Africa for affinity to the serotonin reuptake transport protein. J Ethnopharm 2004; 94:159–163.
  • Chingombe P. An investigation of the Antidepressant-like Effect of Boophone Disticha after Repeated Daily Dosing in a Mouse Model. Bachelor of Pharmacy (Honours) Thesis. University of Zimbabwe, 2010.
  • Nakamura M, Fukushima H. Effect of Fludiazepam on turnover of serotonin in mouse brain. Jpn J Pharmacol 1977; 27:905–908.
  • Risa A, Risa J, Adsersen A, Stafford GI, van Staden J, Jager AK. Acetylcholinesterase inhibitory activity of plants used as memory enhancers in traditional South African medicine. S Afr J Bot 2004; 4:664–666.
  • Zhong J. Amaryllidaceae and Sceletium alkaloids. Nat Prod Rep 2007; 24:886–905.
  • Lopez S, Bastida J, Viladomat F, Codina C. Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sci 2002; 71:2521–2529.
  • Merck Institute. Package insert for Periactin® (Cyproheptadine hydrochloride 4 mg tablets), 1958.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.