Advanced search
Publication Cover
Clinical Toxicology Volume 52, 2014 - Issue 9
Submit an article Journal homepage
1,654
Views
72
CrossRef citations to date
0
Altmetric
Research Article

Cardiac conduction disturbance after loperamide abuse

J. M. MarraffaDepartment of Emergency Medicine, Upstate Medical University, Syracuse NY, USACorrespondence[email protected]
,
M. G. HollandDepartment of Emergency Medicine, Upstate Medical University, Syracuse NY, USA
,
R. W. SullivanDepartment of Emergency Medicine, Upstate Medical University, Syracuse NY, USA
,
B. W. MorganDepartment of Emergency Medicine, School of Medicine, Emory University, Atlanta, GA, USA
,
J. A. OakesDepartment of Emergency Medicine, URMC and Strong Memorial Hospital, Rochester NY, USA
,
T. J. WiegandURMC and Strong Memorial Hospital, Ruth A. Lawrence Poison and Drug Information Center, Rochester, NY, USA
&
M. J. HodgmanDepartment of Emergency Medicine, Upstate Medical University, Syracuse NY, USA
 show all
Pages 952-957 | Received 15 May 2014, Accepted 21 Sep 2014, Published online: 27 Oct 2014

References

  • Centers for Disease Control and Prevention (CDC). Vital signs: overdoses of prescription opioid pain relievers-United States, 1999–2008. MMWR Morb Mortal Wkly Rep 2011; 60:1487–1492.
  • Ward J, Rosenbaum C, Hernon C, McCurdy CR, Boyer EW. Herbal medicines for the management of opioid addiction: safe and effective alternatives to conventional pharmacotherapy? CNS Drugs 2011; 25:999–1007.
  • Daniulaityte R, Carlson R, Falck R, Cameron D, Perera S, Chen L, Sheth A.‘I just wanted to tell you that loperamide WILL WORK’: a web-based study of extra-medical use of loperamide. Drug Alcohol Depend 2013; 130:241–244.
  • Baselt RC. Loperamide. In: Baselt RC, ed. Disposition of Toxic Drugs and Chemicals in Man. 8th ed. Foster City, CA: Biomedical Publications; 2008:854–855.
  • Ekins S, Balakin KV, Savchuk N, Ivanenkov Y. Insights for human ether-a-go-go-related gene potassium channel inhibition using recursive partitioning and Kohonen and Sammon mapping techniques. J Med Chem 2006; 49:5059–5071.
  • Miller J, Zipes D. Therapy for cardiac arrhythmias. In: Mann D, Zipes D, Libby P, Bonow R, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, PA: Elsevier Saunders; 2015:685–720.
  • Jenzer HR, Hagemeijer F. Quinidine syncope: torsade de pointes with low quinidine plasma concentrations. Eur J Cardiol 1976; 4:447–451.
  • Product Information. Imodium(R) capsules, loperamide HCl. 2005.
  • http://www.drugs-forum.com/. Accessed August 20, 2014
  • Audi J, Layher J, Morgan B. Cardiac conduction disturbances secondary to chronic abuse of loperamide: an initial case report. Clin Toxicol 2004; 42:713–826; abstract 22.
  • Berger SI, Ma'ayan A, Iyengar R. Systems pharmacology of arrhythmias. Sci Signal 2010;3:ra30.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.