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Journal of Toxicology: Clinical Toxicology Volume 24, 1986 - Issue 5
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Research Article

Ethylene Glycol Poisoning. The Value of Glycolic Acid Determinations for Diagnosis and Treatment

Tracy P. Hewlett Department of Pharmacology and Therapeutics, Section of Toxicology and Louisiana Regional Poison Control Center Louisiana State University Medical Center in Shreveport, Shreveport, Louisiana, 71130
,
Kenneth E. McMartin Department of Pharmacology and Therapeutics, Section of Toxicology and Louisiana Regional Poison Control Center Louisiana State University Medical Center in Shreveport, Shreveport, Louisiana, 71130
,
Alert J. Lauro Departments of Medicine and Pathology, Louisiana State University Medical Center in New Orleans, New Orleans, Louisiana, 70140
&
Francis Avery Ragan Departments of Medicine and Pathology, Louisiana State University Medical Center in New Orleans, New Orleans, Louisiana, 70140
Pages 389-402 | Published online: 25 Sep 2008

References

  • Marshall T. C. Dose dependent disposition of ethylene glycol in the rat after intravenous administration. J of Toxicol and Environ Health 1982; 10: 397–409
  • Clinical Toxicology of Commercial Products, R. E. Gosselin, H. C. Hodge, R. P. Smith. Williams & Wilkins, Baltimore 1984; 172–179
  • Beasley V. R., Buck W. B. Acute ethylene glycol toxicosis: A review. Vet Human Toxicol 1980; 22: 255–324
  • Winek C. L., Shingleton D. P., Shanor S. P. Ethylene and diethylene glycol toxicity. Clin Tox 1978; 13(2)297–324
  • Jacobsen D., Bredeson J. E., Eide J., Ostborg J. Anion and osmolal gaps in the diagnosis of methanol and ethylene glycol poisoning. Acta Med Scand 1982; 212: 17–20
  • Chou J. Y., Richardson K. E. Effects of pyrazole on ethylene glycol toxicity and metabolism in the rat. Toxicol Appl Pharmacol 1978; 43: 33–44
  • Clay K. L., Murphy R. C. On the metabolic acidosis of ethylene glycol intoxication. Toxicol Appl Pharmacol 1977; 39: 39–49
  • Smith M. S. Solvent toxicity: isopropanol, methanol and ethylene glycol. Ear, Nose & Throat Journal 1983; 62: 126–135
  • Jacobsen D., Ovrebo S., Ostborg J., Sejersted O. M. Glycolate causes the acidosis in ethylene glycol poisoning and is effectively removed by hemodialysis. Acta Med Scand 1984; 216: 409–416
  • Peterson C. D., Collins A. J., Himes J. M., Bullock M. L., Keane W. F. Ethylene glycol poisoning. Pharmacokinetics during therapy with ethanol and hemodialysis. N Eng J Med 1981; 304: 21–23
  • Doedens D. J. Methods for the determination of ethylene glycol. Vet Hum toxicol 1983; 25(2)96–101
  • Gabow P. A., Clay K., Sullivan J. B., Lepoff R. Organic acids in ethylene glycol intoxication. Ann. Intern. Med. 1986; 105: 16–20
  • Hewlett T. P., Ray A. C., Reagor J. C. Diagnosis of ethylene glycol (antifreeze) intoxication in dogs by determination of glycolic acid in serun and urine with high pressure liquid chromatography and gas‐chromatography‐mass spectrometry. J Assoc Off Anal Chem 1983; 66(2)275–283
  • Porter W. H., Auansakul A. Gas‐chromatographic determination of ethylene glycol in serum. Clin Chem 1982; 28(1)75–78
  • Rothman A., Normann S. A., Manoguerra A. S., Bastian J. F., Griswold W. R. Short‐term hemodialysis in childhood ethylene glycol poisoning. J of Pediatrics 1986; 108(1)153–155
  • Emmett M. E., Narins R. G. Clinical use of the anion gap. Medicine 1977; 56: 38–54
  • Litovitz T. The alcohols: ethanol, methanol, isopropanol, ethylene glycol. Ped. Clin. N. Amer. 1986; 33: 311–323
  • Witte D. L. Use of osmol al and anion gap in the clinical toxicology of commonly ingested alcohols: ethanol, methanol, ethylene glycol, isopropanol. AACC TDM‐T 1984; 6(3)1–11

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