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Original Article

ECG Changes and Plasma Concentrations of Propafenone and Its Metabolites in a Case of Severe Poisoning

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Pages 247-251 | Published online: 29 Jul 2009

References

  • Antiarrhythmic drugs. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning, MJ Ellenhorn, DG Barceloux. Williams & Wilkins, Baltimore 1997; 169–187
  • Lewin N A, Goldfrank L R, Osborn H, Howland MA. Antiarrhythmic agents. Goldfrank's Toxicologic Emergencies, LR Goldfrank. Appleton & Lange, Norwalk, CT 1994; 381–389
  • Hii J T, Duff H J, Burgess ED. Clinical pharmacokinetics of propafenone. Gin Pharmacokinet 1991; 21: 1–10
  • Vozeh S, Haefeli W, Ha H R, Vlcek J, Follath F. Nonlinear kinetics of propafenone metabolites in healthy man. Eur J Clin Pharmacol 1990; 38: 509–513
  • Connolly S J, Kates R E, Lebsack C S, Harrison D C, Winkle RA. Clinical pharmacology of propafenone. Circulation 1983; 68: 589–596
  • Chouty F. Intravenous sodium lactate as a treatment of class I anti-arrhythmic agents overdose. Circulation 1989; 80: 411–430
  • Budde T, Beyer M, Breithardt G, Passlick J, Grabensee B. [Therapy of severe propafenone poisoning: An attempt at elimination by hemoper-fusion]. Z Kardiol 1986; 75: 764–769
  • Köppel C, Oberdisse U, Heinemeyer G. Clinical course and outcome in class IC antiarrhythmic overdose. J Toxicol Clin Toxicol 1990; 28: 433–444
  • Kerns W, 2nd, English B, Ford M. Propafenone overdose. Ann Emerg Med 1994; 24: 98–103
  • McHugh T P, Perina DG. Propafenone ingestion. Ann Emerg Med 1987; 16: 437–440
  • Ielasi G, Panagia M, Grasso L, Caminiti G. [Acute voluntary poisoning with propafenone. A clinical case]. Minerva Anestesiol 1993; 59: 69–73
  • Picciotto G, Siragusa V, Cellura M, Ventimiglia C, Rotolo L. [Acute propafenone poisoning. Description of a case]. Minerva Cardioangiol 1990; 38: 555–558
  • Siddoway L A, Thompson K A, McAllister C B. Polymorphism of propafenone metabolism and disposition in man: Clinical and pharmacokinetic consequences. Circulation 1987; 75: 785–791
  • Kates R E, Yee Y G, Winkle RA. Metabolite cumulation during chronic propafenone dosing in arrhythmia. Clin Pharmacol Ther 1985; 37: 610–614
  • Wrighton S A, Stevens JC. The human hepatic cytochromes P450 involved in drug metabolism. Crit Rev Toxicol 1992; 22: 1–21
  • Nattel S, Talajic M, Quantz M, DeRoode M. Frequency-dependent effects of amiodarone on atrioventricular nodal function and slow-channel action potentials: Evidence for calcium channel-blocking activity. Circulation 1987; 76: 442–449

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