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Original

Human Ochratoxicosis

Pages 277-293 | Published online: 24 Sep 2010

References

  • Austwick P. K.C. Balkan nephropathy. The Practitioner 1981; 225: 1031–1038
  • Bacha H., Maaroufi K., Achour A., Hammami M., Ellouz F., Creppy E. E. Ochratoxines et ochratoxicoses humaines en Tunisie. Human Ochratoxicosis and its Pathologies, EE Creppy, M. Castegnaro, G. Dirheimer. Colloque INSERM/John Libbey, Eurotext Ltd, LondonUnited Kingdom 1993; 231: 111–121
  • Baudnmont I., Ahouandjivo R., Creppy E. E. Prevention of lipid peroxidation induced by ochratoxin A in Vero cells in culture by several agents. Chem. Biol. Int. 1997; 104: 29
  • Bauer J., Gareis M. Ochratoxin A in der Nahrungsmittelkette. Z. Veterinmed 1987; 34: 613–627
  • Bemdt W. O., Hayes A. W. In vivo and in vitro changes in renal functions caused by ochratoxin A in the rat. Toxicology 1979; 12: 5–17
  • Boussarie M. A partir dune etude cas-temoins Etude du role de ltochratoxine A chez lthomme dans la survenue de niphropathies interstitielles d'ktiologie indeterminée. Memoire DEA Methodes d'Analyse des Systemes de Santé. Universite de Rennes. 1997; 1
  • Breitholtz A., Olsen M., Dahlback A., Hult K. Plasma ochratoxin A levels in three Swedish populations surveyed using an ion-pair HPLC technique. Food Addit. Contam. 1991; 8: 1983–92
  • Bunge I., Heller K., Roschenthaler R. Isolation and purlfication of ochratoxin A. Z. Lebensm. Unters. Forsch. 1979; 168: 457–458
  • Castegnaro M., Bartsch H., Bereziat J. C., Arvela P., Michelon J., Broussole L. Polymorphic ochratoxin A hydroxylation in rats strains phenotyped as poor and extensive metabolizers of debrisoquine. Xenobiotica 1989; 19: 225–230
  • Castegnaro M., Maru V., Petkova-Bocharova T., Nicolov I. G., Bartsch H. Concentration of ochratoxin A in the urine of endemic nephropathy patients and controls in Bulgaria: lack of detection of 4-hydroxyochratoxin A. Mycotoxins, Endemic Nephropathy and Urinary Tract Tumours, M. Castegnaro, R. Plestina, G. Dirheimer, I. N. Chernozemski, H. Bartsch. IARC Scientific Publication. 1991; 115: 165–169
  • Ceovic S., Hrabar A., Saric M. Epidemiology of Balkan Endemic Nephropathy. Fd. Chem. Toxic 1992; 3: 188, 1983
  • Creppy E. E., Schlegel M., Roschenthaler R., Dirheimer G. Combined action of citrinin and ochratoxin A on hepatoma tissue culture cells. Toxicol. Letters 1980; 5: 375–380
  • Creppy E. E., Stormer F. C., Roschenthaler R., Dirheimer G. Effects of two metabolites of ochratoxin A, (4R)-4-hydroxyochratoxin A and ochratoxin alpha, on immune response in mice. Infection and Immunity 1983; 39(3)1015–1018
  • Creppy E. E., Roschenthaler R., Dirheimer G. Inhibition of protein synthesis in mice by ochratoxin A and its prevention by phenylalanine. Food Chem. Toxicol. 1984; 22(11)883–886
  • Creppy E. E., Kane A., Dirheimer G., Lafarge-Frayssinet C., Mousset S., Frayssinet C. Genotoxicity of ochratoxin A in mice: DNA single-strand break evaluation in spleen liver and kidney. Toxicol. Lett. 1985; 28: 29–35
  • Creppy E. E., Betbeder A. M., Sanchez D., Gharbi Khalef A., Gauret Counord J., Dirheimer G., Bacha H., Hadidane R., Hammami M., El May M., Achour A., Zidane C. Human ochratoxicosis in Northen Africa, correlation with cases of nephropathy. Justus Liebig Universitat Giessen. Mykotoxin-Workshop 1992; 14: 67–68
  • Creppy E. E., Betbeder A. M., Gharbi A., Counord J., Castegnaro M., Bartsch H., Moncharmont P., Fouillet B., Chambon P., Duheimer G. Human ochratoxicosis in France. Mycotoxins, Endemic Nephropathy and Urinary Tract Tumours, M. Castegnaro, R. Plestina, G. Dirheimer, LN. Chernozemsky, H. Bartsch. IARC Scientific Publications, Lyon 1991; 145–151, No. 115
  • Creppy E. E., Castegnaro M., Grosse Y., Meriaux J., Manier C., Moncharmont P., Waller C. Etude de l'ochratoxicose humaine dans trots regions de France: Alsace, Aquitaine et region Rhone-Alpes. Human Ochratoxicosis and its Pathologies, E. E. Creppy, M. Castegnaro, G. Dirheimer. Colloque INSERM/John Libbey, Eurotext Ltd, LondonUnited Kingdom 1993; vol 231: 147–158
  • Creppy E. E., Betbeder A. M., Godin M., Fillastre J. P., Amg K. S., Simon P., Lasseur C., Combe C., Aparicio M. Ochratoxin A in human blood and chronic interstitial nephropathy: cases report in France. Proceedings 17. Mykotoxin-Workshop in der Bundesforschungsanstalt fur Landwirtschaft Braunschweig-Volkenrode. FAL, 15–17 May, 1995-1995
  • Creppy E. E., Baudrimont I., Betbeder A. M. Prevention of nephrotoxicity of ochratoxin A, a food contaminant. Toxicol. Lett. 1995; 82/83: 869–877
  • Creppy E. E., Baudrimont I., Belmadani A., Betbeder A. M. Aspartame as a preventive agent of chronic toxic effects of ochratoxin A in experimental animals. 3. Toxicol. Toxin Rev. 1996; 15(3)207–221
  • De Groene E. M., Hassing G. I.A., Blom M. J., Seinen W., Fink-Gremmels J., Horbach G. J. Development of human cytochrome P450 expressing cell lines; application in mutagenicity testing of ochratoxin A. Cancer Res. 1996a; 56: 299–304
  • De Groene E. M., Jahn A., Horbach G. J., Fink-Gremmels J. Mutagenicity and genotoxicity of the mycotoxin ochratoxin A. Environ. Toxicol. Parmacol. 1996b; 1: 21–26
  • Dirheimer G. Mechanistic approaches to ochratoxin A toxicity. Food Addit. Contam. 1996; 13: 45–48
  • Fukui Y., Hayasaka I., Itoh M., Takouchi Y. Development of neurons and synapses in ochratoxin A - induced microcephalic mice: a quantitative assessment of somatosensory cortex. Neurotoxicology and Teratology 1992; 14: 191–196
  • Galtier P., Alvinerie M., Charpenteau J. L. The pharmacokinetic profiles of ochratoxin A in pigs, rabbits and chickens. Food Cosmet. Toxicol. 1981; 19: 735–738
  • Godin M., Francois A., Le Roy F., Monn J. P., Creppy E. E., Hemet J., Fillastre J. P. Karyomegalic interstitial nephritis. Am. J. Kidney Diseases 1996; 27(1)166
  • Hadidane R., Bacha H., Creppy E. E., Hammami M., Ellouz F., Dirheimer G. Isolation and structure determination of natural analogues of the mycotoxin ochratoxin A produced by Aspergillus ochraceus. Toxicology 1992; 76: 233–243
  • Hult K., Plestina R., Ceovic S., Habazin-Novak V., Radic B. Ochratoxin A in human blood: Analytical results and confirmational tests from a study in connection with Balkan Endemic Nephropathy. Proceedings, V International IUPAC Symposium on Mycotoxins and Phycotoxins. Austrian Chem. Soc, Vienna, Austria 1982a; 338–341, Sept. 1–3, 1982
  • Hult K., Plestina R., Habazin-Novak V., Radic B., Ceovic S. Ochratoxin A in human blood and Balkan endemic nephropathy. Arch. Toxicol. 1982; 51: 313–321
  • IARC (International Agency for Research on Cancer)Some naturally occuring substances: Some food items and constituents, spices, pyrolysis products and mycotoxins. IARC monographs on the evaluation of carcinogenic risks to humans, Lyon 1993; volume 56
  • Kane A., Creppy E. E., Roschenthaler R., Dirheimer G. Changes in urinary and renal tubular enzymes caused by subchronic adrmnistration of ochratoxin A in rats. Toxicology 1986; 42: 233–243
  • Kanisawa M., Suzuki S. Induction of renal and hepatic tumours in mice by ochratoxin A, a mycotoxin. Gann. 1978; 69: 599–600
  • Kanisawa M. Synergistic effects of citrinin on hepatorenal carcinogenesis of OTA in mice. Toxigenic Fungi - Their Toxins and Health, H. Hazard Kurata, Y. Ueno, Kodansha, Tokyo/Elsevier, Amsterdam 1984; 245–254
  • Kawamura O., Malu S., Sato S., Ueno Y. Ochratoxin A in livestock and human sera in Japan quantified by a sensitive ELISA. Human Ochratoxicosis and its Pathologies, E. E. Creppy, M. Castegnaro, G. Dirheimer. Colloque INSERM/John Libbey, Eurotext Ltd, LondonUK 1993; 231: 159–165
  • Khalef A., Zidane C., Charef A., Gharbi IA., Tadjerouna M., Betbeder A. M., Creppy E. E. Ochratoxicose humaine en Algerie. Human Ochratoxicosis and its Pathologies, E. E. Creppy, M. Castegnaro, G. Dirheimer. Colloque INSERM/John Libbey, Eurotex, LondonUK 1993; 231: T123–127
  • Krogh P., Hald B., Pedersen E. J. Occurrence of ochratoxin A and citrinin in cereals associated with porcine nephropathy. Acta Pathol. Microbiol. Scand. (B) 1973; 81: 689–695
  • Krogh P., Axelsen N. H., Wiling F., Gyrd-Hansen N., Hald B., Hylgaard-Jensen J., Hen A. E., Madsen A., Mortensen H. P., Moller T., Petersen O. K., Ravnskov U., Rostgaard M., Aalund O. Experimental porcine nephropathy. Changes of renal function and structure induced by ochratoxin Asontamin ated feed. Acta Pathol. Microbiol. Scand. (A) 1974; 246: 1–21
  • Krogh P. Ochratoxins. Mycotoxins in Human and Animal health, J. V. Rodricks, C. W. Esseltine, M. A. Mehlmann. Pathotox Pub, Illinois 1977; 489–498
  • Krogh P. Ochratoxins in food. Mycotoxin in Food, P. Krogh. Academic Pres, New York 1987; S97–121
  • Kuiper-Goodman T., Scott P. M. Risk Assessment of the mycotoxin ochratoxin A. BiornedicaLand Environmental Sciences 1989; 2: 179–248
  • Kuiper-Goodman T., Ominski K., Marquardt R. R., Malcolm S., Mc Mullen E., Lombaert G. A., Morton T. Estimating human exposure to ochratoxin A in Canada. Human Ochratoxicosis and its Pathologies, E. E. Creppy, M. Castegnaro, G. Dirheimer. Colloque INSERM/John Libbey, Eurotext Ltd, LondonUK 1993; 231: 167–174
  • Maaroufi K., Achour A., Hammami M., El May M., Betbeder A. M., Ellouz F., Creppy E. E., Bacha H. Ochratoxin A in human blood in relation to nephropathy in Tunisia. Hum.& Exper. Toxicology 1995a; 14: 609–615
  • Maaroufi K., Achour A., Betbeder A. M., Hammami M., Ellouz F., Creppy E. E., Bacha H. Foodstufs and human blood contamination by the mycotoxin ochratoxin A: correlation with chronic interstitial nephropathy in Tunisia. Arch. Toxicol. 1995b; 69: 552–558
  • Maaroufi K., Achour A., Zakhama A., Ellouz F., El-May M., Creppy E. E., Bacha H. Human nephropathy related to Ochratoxin A in Tunisia. J. ToxicoL-Toxin Review 1996; 15(3)223–237
  • Manolova Y., Manolov G., Parvanova L., Petkova-Bocharova T., Castegnaro M., Chernozemsky I. N. Induction of characteistic chromosomal aberrations, particularly X-trisomy, in cultured human Iymphocytes treated by ochratoxin A, a mycotoxin implicated in Balkan endemic nephropathy. Mutat. Res. 1990; 292: 143–149
  • Mantle P. G., McHugh K. M., Adatia R., Heaton J. M., Gray T., Turner D. R. Penicillium aurantiognseum-induced, persistent renal hispathological changes in rats, an experimental model for Balkan endemic nephropathy competitive with ochratoxin A. Mycotoxins, Endemic Nephropathy and Urinary Tract Tumours, M. Castegnaro, R. Plestina, G. Dirheimer, H. N. Chernozemsky, H. Bartsch. International Agency for Research on Cancer, LyonFrance 1991; 119–27
  • Mantle P. G., McHugh K. M. Nephrotoxic fungi in foods from nephropathy households in Bulgaria. Mycol. Res. 1993; 97: 205–212
  • Mayura K., Parker R., Berndt W. O., Phillips T. D. Ochratoxin A - induced teratogenesis in rats: partial protection by phenylalanine. Appl. Environ. Microbiol. 1984; 48: 11861188
  • Meisner H., Meisner P. Ochratoxin A, in vivo inhibitor of renal phosphoenolpyruvate carboxykinase. Arch. Biochem. Biophys. 1981; 208: 146–153
  • NTP (National Toxicology Program)NTP Technical Report on the Toxicology and Carcinogenesis Studies of Ochratoxin A (CAS No. 303–47–9) in F3441N Rats (Gavage studies), G. Boorman. US Department of Health and Human Services, National Institutes of Health. Research Trianglc Park, NC 1989, NIH Publication No. 89–2813
  • Olsen J. H., Hald B., Thorup I. Carstensen Distribution in Denmark of porcine nephropathy and chronic disorders of the urinary tract in humans. Human Ochratoxicosis and its Pathologies, E. E. Creppy, M. Castegnaro, G. Dirheimer. Colloque INSERM/John Libbey, Eurotext Ltd, LondonUK 1993; 231: 209–216
  • Petkova-Bocharova T., Chemorernski I. N., Castegnaro M. Ochratoxin A in human blood in relation to Balkan Endemic Nephropathy and unnaq system tumours in Bulgaria. Food Addit. Contam 1988; 5(3)199–301
  • Petkova-Bocharova T., Castegnaro M. Ochratoxin A in human blood in relation to Balkan endemic nephropathy and unnary tract tumours in Bulgana. Mycotoxins. Endemic Nephropathy and Urinary Tract Tumours, M. Castegnaro, R. Plestina, G. Dirheimer, I. N. Chemozemsky, H. Bailsch. IARC Scientific Publications, Lyon 1991; 115: 135–137
  • Rahimtula A. D., Bereziat J. C., Bussachini-Griot V., Bartsch H. Lipid peroxidation as a possible cause of ochratoxin A toxicity. Biochem. Parmacol. 1988; 37: 4469–4477
  • Speijers G. J.A., van Egmond H. P. Worldwide ochratoxin A levels in food and feeds. Human ochratoxicosis and its Pathologies, E. E. Creppy, M. Castegnaro, G. Dirheimer. Colloque INSERM/John Libbey Eurotext Ltd. 1993; 231: 85–100
  • Steyn P. S., Holzapfel C. W., Ferreira N. P. Biosynthesis of the ochratoxins, metabolites of Aspergillus ochraceus. Phytochem. 1970; 9: 1977–1983
  • Steyn P. S., Holzapfel C. W. The isolation of the methyl and ethyl esters of ochratoxins A and B, metabolites of Aspergillus ochruccus. Wilh. J. S. Afr. Chem. Inst. 1967a; 20: 186189
  • Steyn P. S., Holzapfel C. W. The synthesis of ochratoxins A and B, metabolites of Aspergillus ochraceus. With. Tetrahedron 1967b; 23: 4449–4461
  • Suzuki S., Moroi K., Kanisawa M., Satoh T. Effects of drug metabolizing enzyme inducers on carcinogenesis and toxicity of ochratoxin A in mice. (Abstract). Toxicol. Letters 1986; 31: 206, Suppl
  • Thuvander A., Breitholtz-Emanuelson A., Brabencova D., Gadhasson I. Influence of perinatal ochratoxin A exposure on the immune system in mice. Food Chem. Toxicol. 1996; 34(6)547–554
  • Thuvander A., Dahl P., Breitholtz-Emanuelson A. Prenatal exposure of Balb/c mice to ochratoxin A: effects on the immune system in the offsprings. Nat. Toxins 1997; 4(4)174–180
  • van der Menve K. J., Steyn P. S., Foune L. Ochratoxin A, a toxic metabolite produced by Aspergillus ochraceus With. Nature 1965a; 205(4976)112–1113
  • van der Merwe K. J., Steyn P. S., Foune L. Mycotoxins Part II. The constitution of ochratoxins A, B and C, metabolites of Aspergillus ochraceus With. J. Chem. Soc 1965b; 7083–7088
  • van Egmond H. P., Speijers G. J.A. Survey of data on the incidence and levels of ochratoxin A in food and animal feed world-wide. J. Nat. Tox. 1994; 3(2)125–144
  • Wafa E. W., Yahya R. S., Sobh M. A., Eraky I., El-Baz M., El-Gayar H. A.M., Betbeder A. M., Creppy E. E. Human & Experimental. Toxicology 1998; 17: 124–129

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