Abnormal body perception and neural activity in the insula in depression: An fMRI study of the depressed “material me”

References

• Ashburner J, Friston KJ. 1999. Nonlinear spatial normalization using basis functions. Hum Brain Mapp 7:254–266.
   PubMed Web of Science ®Google Scholar
• Bar KJ, Wagner G, Koschke M, Boettger S, Boettger MK, Schlosser R, Sauer H. 2007. Increased prefrontal activation during pain perception in major depression. Biol Psychiatry 62:1281–1287.
   PubMedGoogle Scholar
• Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. 1961. An inventory for measuring depression. Arch Gen Psychiatry 4:561–571.
   PubMed Web of Science ®Google Scholar
• Beck AT, Weissman A, Lester D, Trexler L. 1974. The measurement of pessimism: the hopelessness scale. J Consult Clin Psychol 42:861–865.
   PubMed Web of Science ®Google Scholar
• Brett M, Anton J-L, Valabregue R, Poline J–B. 2002. Region of interest analysis using an SPM toolbox [abstract]. Paper presented at the International Conferance on Functional Mapping of the Human Brain.
   Google Scholar
• Brody AL, Saxena S, Stoessel P, Gillies LA, Fairbanks LA, Alborzian S, . 2001. Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: preliminary findings. Arch Gen Psychiatry 58:631–640.
   PubMed Web of Science ®Google Scholar
• Craig AD. 2002. How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci 3: 655–666.
   PubMed Web of Science ®Google Scholar
• Craig AD. 2003. Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol 13:500–505.
   PubMed Web of Science ®Google Scholar
• Craig AD. 2004. Human feelings: why are some more aware than others? Trends Cogn Sci 8:239–241.
   PubMed Web of Science ®Google Scholar
• Craig AD. 2009. How do you feel – now? The anterior insula and human awareness. Nat Rev Neurosci 10:59–70.
   PubMed Web of Science ®Google Scholar
• Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ. 2004. Neural systems supporting interoceptive awareness. Nat Neurosci 7:189–195.
   PubMed Web of Science ®Google Scholar
• Critchley HD, Rotshtein P, Nagai Y, O'Doherty J, Mathias CJ, Dolan RJ. 2005. Activity in the human brain predicting differential heart rate responses to emotional facial expressions. Neuroimage 24:751–762.
   PubMed Web of Science ®Google Scholar
• Damasio AR. 1999. How the brain creates the mind. Sci Am 281:112–117.
   PubMed Web of Science ®Google Scholar
• Dunn BD, Dalgleish T, Ogilvie AD, Lawrence AD. 2007. Heartbeat perception in depression. Behav Res Ther 45:1921–1930.
   PubMed Web of Science ®Google Scholar
• Fitzgerald PB, Laird AR, Maller J, Daskalakis ZJ. 2008. A meta-analytic study of changes in brain activation in depression. Hum Brain Mapp 29:683–695.
   PubMed Web of Science ®Google Scholar
• Friston KJ, Holmes AP, Worsley KJ, Poline JB, Frith C, Frackowiak RSJ. 1995. Statistical parametric maps in functional imaging: A general linear approach. Hum Brain Mapping 2:189–210.
   Google Scholar
• Friston KJ, Fletcher P, Josephs O, Holmes A, Rugg MD, Turner R. 1998. Event-related fMRI: characterizing differential responses. Neuroimage 7:30–40.
   PubMed Web of Science ®Google Scholar
• Frodl T, Scheuerecker J, Albrecht J, Kleemann AM, Muller-Schunk S, Koutsouleris N, . 2007. Neuronal correlates of emotional processing in patients with major depression. World J Biol Psychiatry 8:1–7.
   Google Scholar
• Garcia-Cebrian A, Gandhi P, Demyttenaere K, Peveler R. 2006. The association of depression and painful physical symptoms – a review of the European literature. Eur Psychiatry 21:379–388.
   PubMed Web of Science ®Google Scholar
• Gillihan SJ, Farah MJ. 2005. Is self special? A critical review of evidence from experimental psychology and cognitive neuroscience. Psychol Bull 131:76–97.
   PubMed Web of Science ®Google Scholar
• Goldstein RZ, Alia-Klein N, Tomasi D, Zhang L, Cottone LA, Maloney T, . 2007. Is decreased prefrontal cortical sensitivity to monetary reward associated with impaired motivation and self-control in cocaine addiction? Am J Psychiatry 164:43–51.
   PubMed Web of Science ®Google Scholar
• Grimm S, Boesiger P, Beck J, Schuepbach D, Bermpohl F, Walter M, Ernst J, Hell D, Boeker H, Northoff G. 2009a. Altered negative BOLD responses in the default-mode network during emotion processing in depressed subjects. Neuropsychopharmacology 34(4):932–843.
   PubMed Web of Science ®Google Scholar
• Grimm S, Ernst J, Boesiger P, Schuepbach D, Hell D, Boeker H, Northoff G. 2009b. Increased self-focus in major depressive disorder is related to neural abnormalities in subcortical-cortical midline structures. Hum Brain Mapp 30(8):2617–27.
   PubMedGoogle Scholar
• Horn W. 1983. L-P-S Leistungsprüfsystem. Göttingen: Hogrefe.
   Google Scholar
• Ingram RE. 1990. Self-focused attention in clinical disorders: review and a conceptual model. Psychol Bull 107:156–176.
   PubMed Web of Science ®Google Scholar
• Keedwell PA, Andrew C, Williams SC, Brammer MJ, Phillips ML. 2005. The neural correlates of anhedonia in major depressive disorder. Biol Psychiatry 58:843–853.
   PubMed Web of Science ®Google Scholar
• Kirmayer LJ. 2001. Cultural variations in the clinical presentation of depression and anxiety: implications for diagnosis and treatment. J Clin Psychiatry 62(Suppl 13):22–28; discussion 29–30.
   PubMedGoogle Scholar
• Lamm C, Decety J. 2008. Is the extrastriate body area (EBA) sensitive to the perception of pain in others? Cereb Cortex 18:2369–2373.
   PubMed Web of Science ®Google Scholar
• Lehrl S. 1995. Mehrfachwahl-Wortschatz-Intelligentest (MWT-B). Göttingen: Hogrefe.
   Google Scholar
• Mayberg H. 2002. Depression, II: localization of pathophysiology. Am J Psychiatry 159:1979.
   PubMedGoogle Scholar
• Mayberg HS. 2003. Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment. Br Med Bull 65:193–207.
   PubMed Web of Science ®Google Scholar
• Milak MS, Parsey RV, Keilp J, Oquendo MA, Malone KM, Mann JJ. 2005. Neuroanatomic correlates of psychopathologic components of major depressive disorder. Arch Gen Psychiatry 62:397–408.
   PubMed Web of Science ®Google Scholar
• Montgomery SA, Asberg M. 1979. A new depression scale designed to be sensitive to change. Br J Psychiatry 134:382–389.
   PubMed Web of Science ®Google Scholar
• Nichols T, Hayasaka S. 2003. Controlling the familywise error rate in functional neuroimaging: a comparative review. Stat Methods Med Res 12:419–446.
   PubMed Web of Science ®Google Scholar
• Northoff G. 2007. Psychopathology and pathophysiology of the self in depression – neuropsychiatric hypothesis. J Affect Disord 104:1–14.
   PubMed Web of Science ®Google Scholar
• Northoff G, Heinzel A, de Greck M, Bermpohl F, Dobrowolny H, Panksepp J. 2006. Self-referential processing in our brain – a meta-analysis of imaging studies on the self. Neuroimage 31:440–457.
   PubMed Web of Science ®Google Scholar
• Nyboe Jacobsen L, Smith Lassen I, Friis P, Videbech P, Wentzer Licht R. 2006. Bodily symptoms in moderate and severe depression. Nord J Psychiatry 60:294–298.
   PubMed Web of Science ®Google Scholar
• Panksepp J. 1998. Affective neuroscience – The foundations of human and animal emotions. New York, Oxford: Oxford University Press.
   Google Scholar
• Paulus MP, Stein MB. 2006. An insular view of anxiety. Biol Psychiatry 60:383–387.
   PubMed Web of Science ®Google Scholar
• Perico CA, Skaf CR, Yamada A, Duran F, Buchpiguel CA, Castro CC, . 2005. Relationship between regional cerebral blood flow and separate symptom clusters of major depression: a single photon emission computed tomography study using statistical parametric mapping. Neurosci Lett 384: 265–270.
   PubMed Web of Science ®Google Scholar
• Phillips ML, Drevets WC, Rauch SL, Lane R. 2003a. Neurobiology of emotion perception I: The neural basis of normal emotion perception. Biol Psychiatry 54:504–514.
   PubMed Web of Science ®Google Scholar
• Phillips ML, Drevets WC, Rauch SL, Lane R. 2003b. Neurobiology of emotion perception II: Implications for major psychiatric disorders. Biol Psychiatry 54:515–528.
   PubMed Web of Science ®Google Scholar
• Pollatos O, Schandry R, Auer DP, Kaufmann C. 2007. Brain structures mediating cardiovascular arousal and interoceptive awareness. Brain Res 1141:178–187.
   PubMed Web of Science ®Google Scholar
• Pollatos O, Traut-Mattausch E, Schandry R. 2009. Differential effects of anxiety and depression on interoceptive accuracy. Depress Anxiety 26:167–173.
   PubMed Web of Science ®Google Scholar
• Porges SW. 1993. Body Perception Questionnaire (German version). Laboratory of Developmental Assessment, University of Maryland.
   Google Scholar
• Raichle ME, Gusnard DA. 2005. Intrinsic brain activity sets the stage for expression of motivated behavior. J Comp Neurol 493:167–176.
   PubMed Web of Science ®Google Scholar
• Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. 2001. A default mode of brain function. Proc Natl Acad Sci USA 98:676–682.
   PubMed Web of Science ®Google Scholar
• Rimes KA, Watkins E. 2005. The effects of self-focused rumination on global negative self-judgements in depression. Behav Res Ther 43:1673–1681.
   PubMed Web of Science ®Google Scholar
• Saxe R, Brett M, Kanwisher N. 2006. Divide and conquer: a defense of functional localizers. Neuroimage 30:1088–1096; discussion 1097–1099.
   PubMed Web of Science ®Google Scholar
• Simmons A, Strigo I, Matthews SC, Paulus MP, Stein MB. 2006. Anticipation of aversive visual stimuli is associated with increased insula activation in anxiety-prone subjects. Biol Psychiatry 60:402–409.
   PubMed Web of Science ®Google Scholar
• Stein MB, Simmons AN, Feinstein JS, Paulus MP. 2007. Increased amygdala and insula activation during emotion processing in anxiety-prone subjects. Am J Psychiatry 164:318–327.
   PubMed Web of Science ®Google Scholar
• Stewart SH, Buffett-Jerrott SE, Kokaram R. 2001. Heartbeat awareness and heart rate reactivity in anxiety sensitivity: a further investigation. J Anxiety Disord 15:535–553.
   PubMedGoogle Scholar
• Strigo IA, Simmons AN, Matthews SC, Craig AD, Paulus MP. 2008a. Association of major depressive disorder with altered functional brain response during anticipation and processing of heat pain. Arch Gen Psychiatry 65:1275–1284.
   PubMed Web of Science ®Google Scholar
• Strigo IA, Simmons AN, Matthews SC, Craig AD, Paulus MP. 2008b. Increased affective bias revealed using experimental graded heat stimuli in young depressed adults: evidence of “emotional allodynia”. Psychosom Med 70:338–344.
   PubMed Web of Science ®Google Scholar
• Treynor. 2003. Rumination reconsidered: a psychometric analysis. Cogn Ther Res 27:247–259.
   Web of Science ®Google Scholar
• Tylee A, Gandhi P. 2005. The importance of somatic symptoms in depression in primary care. Prim Care Companion J Clin Psychiatry 7:167–176.
   PubMedGoogle Scholar
• Vul E, Harris C, Winkielman P, Pashler H. 2009. Puzzlingly High Correlations in fMRI Studies of Emotion, Personality, and Social Cognition. Perspectives on Psychological Science 4(3):274–290.
   Web of Science ®Google Scholar