Serotonergic neurotransmission in early Parkinson's disease: A pilot study to assess implications for depression in this disorder

References

• Azmitia EC. 2007. Serotonin and brain: Evolution, neuroplasticity, and homeostasis. Int Rev Neurobiol 77:31–56.
   PubMed Web of Science ®Google Scholar
• Beck AT, Ward CH, Mendelson M, Mock J, Erbraugh J. 1961. An inventory for measuring depression. Arch Gen Psychiatry 4:561–571.
   PubMed Web of Science ®Google Scholar
• Borah A, Mohanakumar KP. 2007. Long-term l-dopa treatment causes indiscriminate increase in dopamin levels at the cost of serotonin synthesis in discrete brain regions of rats. Cell Mol Neurobiol 27(8):985–996.
   Google Scholar
• Bouthenet ML, Martres MP, Sales N, Schwartz JC. 1987. A detailed mapping of dopamine D-2 receptors in rat central nervous system by autoradiography with [125I]iodosulpride. Neuroscience 20:117–155.
   Google Scholar
• Carrillo-de-la-Pena MT. 1992. ERP augmenting/reducing and sensation seeking: a critical review. Int J Psychophysiol 12:211–220.
   Google Scholar
• Carta M, Lindgren HS, Lundblad M, Stancampiano R, Fadda F, Cenci MA. 2006. Role of striatal L-DOPA in the production of dyskinesia in 6-hydroxydopamine lesioned rats. J Neurochem 96:1718–1727.
   Google Scholar
• Carta M, Carlsson T, Kirik D, Bjorklund A. 2007. Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats. Brain 130:1819–1833.
   PubMed Web of Science ®Google Scholar
• Chang L. 1978. Method for attenuation correction in radionuclide computed tomography. Trans Nucl Sci 25:638–643.
   Web of Science ®Google Scholar
• Chen TJ, Yu YW, Chen MC, Wang SY, Tsai SJ, Lee TW. 2005. Serotonin dysfunction and suicide attempts in major depressives: an auditory event-related potential study. Neuropsychobiology 52:28–36.
   Google Scholar
• Chinaglia G, Landwehrmeyer B, Probst A, Palacios JM. 1993. Serotoninergic terminal transporters are differentially affected in Parkinson's disease and progressive supranuclear palsy: an autoradiographic study with [3H]citalopram. Neuroscience 54:691–699.
   Google Scholar
• Devos D, Lefebvre L, Bordet R. 2010. Dopaminergic and non-dopaminergic pharmacological hypotheses for gait disorders in Parkinson's disease. Fundam Clin Pharmacol. Epub ahead of print.
   Google Scholar
• Doder M, Rabiner EA, Turjanski N, Lees AJ, Brooks DJ. 2003. Tremor in Parkinson's disease and serotonergic dysfunction: an 11C-WAY 100635 PET study. Neurology 60:601–605.
   PubMedGoogle Scholar
• Fahn S, Elton R. 1987. Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale. Fahn S, Marsden SD, Goldstein M, . Recent developments in Parkinson's disease II. New York: Macmillan, 111–123.
   Google Scholar
• Fox SH, Chuang R, Brotchie JM. 2009. Serotonin and Parkinson's disease: On movement, mood, and madness. Mov Dis 24(9):1255–1266.
   Google Scholar
• Gil S, Park C, Lee J, Koh H. 2010. The roles of striatal serotonin and l:-amino-acid decarboxylase on l-dopa-induced dyskinesia in a hemiparkinsonian rat model. Cell Mol Neurobiol. Epub ahead of print.
   Google Scholar
• Halliday GM, Li YW, Blumbergs PC, Joh TH, Cotton RG, Howe PR, . 1990a. Neuropathology of immunohistochemically identified brainstem neurons in Parkinson's disease. Ann Neurol 27:373–385.
   PubMed Web of Science ®Google Scholar
• Halliday GM, Blumbergs PC, Cotton RG, Blessing WW, Geffen LB. 1990b. Loss of brainstem serotonin- and substance P-containing neurons in Parkinson's disease. Brain Res 510:104–107.
   PubMed Web of Science ®Google Scholar
• Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56–62.
   PubMed Web of Science ®Google Scholar
• Hegerl U, Juckel G. 1993. Intensity dependence of auditory evoked potentials as an indicator of central serotonergic neurotransmission: a new hypothesis. Biol Psychiatry 33:173–187.
   PubMed Web of Science ®Google Scholar
• Hegerl U, Juckel G, Moller HJ. 1996. Event related brain potentials as indicators of neurochemical dysfunctions in psychiatric patients. Nervenarzt 67:360–368.
   Google Scholar
• Hegerl U, Gallinat J, Juckel G. 2001. Event-related potentials. Do they reflect central serotonergic neurotransmission and do they predict clinical response to serotonin agonists? J Affect Disord 62:93–100.
   PubMed Web of Science ®Google Scholar
• Hughes AJ, Daniel SE, Kilford L, Lees AJ. 1992. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55:181–184.
   PubMed Web of Science ®Google Scholar
• Jacobs BL, Azmitia EC. 1992. Structure and function of the brain serotonin system. Physiol Rev 72:165–229.
   PubMed Web of Science ®Google Scholar
• Juckel G, Molnar M, Hegerl U, Csépe V. 1997. Karmos G. Auditory-evoked potentials as indicator of brain serotonergic activity–first evidence in behaving cats. Biol Psychiatry 41:1181–1195.
   PubMed Web of Science ®Google Scholar
• Juckel G, Hegerl U, Molnar M, Csépe V, Karmos G. 1999. Auditory evoked potentials reflect serotonergic neuronal activity – a study in behaving cats administered drugs acting on 5-HT1A autoreceptors in the dorsal raphe nucleus. Neuropsychopharmacology 21:710–716.
   PubMed Web of Science ®Google Scholar
• Juckel G, Gallinat J, Riedel M, Sokullu S, Schulz C, Möller HJ, . 2003. Serotonergic dysfunction in schizophrenia assessed by the loudness dependence measure of primary auditory cortex evoked activity. Schizophr Res 64:115–124.
   PubMedGoogle Scholar
• Kääriäinen TM, García-Horsman JA, Piltonen M., Huotari M, Männistö PT. 2008. Serotonergic activation after 2-week intrastriatal infusion of l-dopa and slow recovery of circling in rats with unilateral nigral lesions. Basic Clin Pharmacol Toxicol 102(3):300–307.
   Google Scholar
• Kulisevsky J, Pagonabarraga J, Pacual-Sedano B, Gironell A, García-Sánchez C, Martínez-Corral M. 2008. Motor changes during sertraline treatment in depressed patients with Parkinson's disease. Eur J Neurol 15:953–959.
   Google Scholar
• Le MM, Simon H. 1991. Mesocorticolimbic dopaminergic network: functional and regulatory roles. Physiol Rev 71:155–234.
   PubMed Web of Science ®Google Scholar
• Leentjens AF, Van den Akker M, Metsemakers JF, Lousberg R, Verhey FR. 2003. Higher incidence of depression preceding the onset of Parkinson's disease: a register study. Mov Disord 18:414–418.
   PubMed Web of Science ®Google Scholar
• Linka T, Muller BW, Bender S, Sartory G. 2004. The intensity dependence of the auditory evoked N1 component as a predictor of response to Citalopram treatment in patients with major depression. Neurosci Lett 367:375–378.
   Google Scholar
• Linka T, Muller BW, Bender S, Sartory G, Gastpar M. 2005. The intensity dependence of auditory evoked ERP components predicts responsiveness to reboxetine treatment in major depression. Pharmacopsychiatry 38:139–143.
   PubMed Web of Science ®Google Scholar
• Mayeux R. 1990. The ‘serotonergic hypothesis’ for depression in Parkinson's disease. Adv Neurol 53:163–166.
   PubMedGoogle Scholar
• Mendlin A, Martin FJ, Jacobs BL. 1999. Dopaminergic input is required for increases in serotonin output produced by behavioral activation: an in vivo microdialysis study in rat forebrain. Neuroscience 93:897–905.
   PubMed Web of Science ®Google Scholar
• Nagatsu T, Sawada M. 2009. L-dopa therapy for Parkinson's disease: Past, present, and future. Parkinsonism Relat Disord 15(Suppl 1):3–8.
   Google Scholar
• Nilsson FM, Kessing LV, Sorensen TM, Andersen PK, Bolwig TG. 2002. Major depressive disorder in Parkinson's disease: a register-based study. Acta Psychiatr Scand 106:202–211.
   Google Scholar
• Norra C, Mrazek M, Tuchtenhagen F, Gobbelé R, Buchner H, Sass H, . 2003. Enhanced intensity dependence as a marker of low serotonergic neurotransmission in borderline personality disorder. J Psychiatr Res 37:23–33.
   PubMedGoogle Scholar
• O'Neill BV, Croft RJ, Leung S, Guille V, Galloway M, Phan KL, . 2006. Dopamine receptor stimulation does not modulate the loudness dependence of the auditory evoked potential in humans. Psychopharmacology (Berlin) 188:92–99.
   Google Scholar
• Paige SR, Fitzpatrick DF, Kline JP, Balogh SE, Hendricks SE. 1994. Event-related potential amplitude/intensity slopes predict response to antidepressants. Neuropsychobiology 30:197–201.
   PubMedGoogle Scholar
• Peyron C, Luppi PH, Kitahama K, Fort P, Hermann DM, Jouvet M. 1995. Origin of the dopaminergic innervation of the rat dorsal raphe nucleus. Neuroreport 6:2527–2531.
   PubMed Web of Science ®Google Scholar
• Pogarell O, Tatsch K, Juckel G, Hamann C, Mulert C, Pöpperl G, . 2004. Serotonin and dopamine transporter availabilities correlate with the loudness dependence of auditory evoked potentials in patients with obsessive-compulsive disorder. Neuropsychopharmacology 29:1910–1917.
   Google Scholar
• Pogarell O, Poepperl G, Mulert C, Hamann C, Sadowsky N, Riedel M, . 2005. SERT and DAT availabilities under citalopram treatment in obsessive-compulsive disorder (OCD). Eur Neuropsychopharmacology 15:521–524.
   PubMed Web of Science ®Google Scholar
• Schrag A, Barone P, Brown RG, Schrag A, Barone P, Brown RG, . 2007. Depression rating scales in Parkinson's disease: critique and recommendations. Mov Disord 22:1077–1092.
   PubMed Web of Science ®Google Scholar
• Sodhi MS, Sanders-Bush E. 2004. Serotonin and brain development. Int Rev Neurobiol 59:111–174.
   PubMed Web of Science ®Google Scholar
• Taylor TN, Caudle WM, Shepherd KR, Noorian A, Jackson CR, Iuvone PM, Weinshenker D, Greene JG, Miller GW. 2009. Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity. J Neurosci 24:8103–8113.
   Google Scholar
• Walter U, Hoeppner J, Prudente-Morrissey L, Horowski S, Herpertz SC, Benecke R. 2007. Parkinson's disease-like midbrain sonography abnormalities are frequent in depressive disorders. Brain 130:1799–1807.
   PubMed Web of Science ®Google Scholar
• Wang Y, Jeng CH, Lin JC, Wang JY. 1996. Serotonin modulates ethanol-induced depression in cerebellar Purkinje neurons. Alcohol Clin Exp Res 20:1229–1236.
   Google Scholar
• Winter C, von Rumohr A, Mundt A, Petrus D, Klein J, Lee T, et al. 2007. Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats. Behav Brain Res 184:133–141.
   PubMed Web of Science ®Google Scholar