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REVIEW ARTICLES

Safety and efficacy of repetitive transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder: A review

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Pages 164-177 | Received 16 Aug 2010, Accepted 16 Mar 2011, Published online: 30 May 2011

References

  • Aleman A, Sommer IE, Kahn RS. 2007. Efficacy of slow repetitive transcranial magnetic stimulation in the treatment of resistant auditory hallucinations in schizophrenia: a meta-analysis. J Clin Psychiatry 68:416–421.
  • Alonso P, Pujol J, Cardoner N, Benlloch L, Deus J, Menchon JM, . 2001. Right prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: a double-blind, placebo-controlled study. Am J Psychiatry 158:1143–1145.
  • Alptekin K, Degirmenci B, Kivircik B, Durak H, Yemez B, Derebek E, . 2001. Tc-99m HMPAO brain perfusion SPECT in drug-free obsessive-compulsive patients without depression. Psychiatry Res 107:51–56.
  • American Psychiatric Association. 2000. Diagnostic and statistical manual of mental disorders (DSM-IV-TR). 2000. 4th text revision. Washington, DC, American Psychiatric Association.
  • Aouizerate B, Guehl D, Cuny E, Rougier A, Bioulac B, Tignol J, . 2004. Pathophysiology of obsessive-compulsive disorder: a necessary link between phenomenology, neuropsychology, imagery and physiology. Prog Neurobiol 72:195–221.
  • Atmaca M, Yildirim H, Ozdemir H, Ozler S, Kara B, Ozler Z, . 2008. Hippocampus and amygdalar volumes in patients with refractory obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry 32:1283–1286.
  • Barker AT, Jalinous R, Freeston IL. 1985. Non-invasive magnetic stimulation of human motor cortex. Lancet 1:1106–1107.
  • Baxter LR Jr, Schwartz JM, Mazziotta JC, Phelps ME, Pahl JJ, Guze BH, . 1988. Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder. Am J Psychiatry 145:1560–1563.
  • Beglinger LJ, Paulsen JS, Watson DB, Wang C, Duff K, Langbehn DR, . 2008. Obsessive and compulsive symptoms in prediagnosed Huntington's disease. J Clin Psychiatry 69: 1758–1765.
  • Ben-Shachar D, Belmaker RH, Grisaru N, Klein E. 1997. Transcranial magnetic stimulation induces alterations in brain monoamines. J Neural Transm 104:191–197.
  • Bridges PK, Goktepe EO, Maratos J. 1973. A comparative review of patients with obsessional neurosis and with depression treated by psychosurgery. Br J Psychiatry 123(577):663–674.
  • Brunelin J, Poulet E, Boeuve C, Zeroug-vial H, d'Amato T, Saoud M. 2007. Efficacy of repetitive transcranial magnetic stimulation (rTMS) in major depression: a review [Article in French]. Encephale 33:126–134.
  • Chamberlain SR, Fineberg NA, Blackwell AD, Robbins TW, Sahakian BJ. 2006. Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania. Am J Psychiatry 163:1282–1284.
  • Chen R, Classen J, Gerloff C, Celnik P, Wassermann EM, Hallett M, . 1997. Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology 48:1398–1403.
  • Cohen LG, Roth BJ, Nilsson J, Dang N, Panizza M, Bandinelli S, . 1990. Effects of coil design on delivery of focal magnetic stimulation. Technical considerations. Electroencephalogr Clin Neurophysiol 75:350–357.
  • de la Fuente-Fernandez R, Schulzer M, Stoessl AJ. 2002. The placebo effect in neurological disorders. Lancet Neurol 1:85–91.
  • Dell'Osso B, Altamura AC, Allen A, Hollander E. 2005. Brain stimulation techniques in the treatment of obsessive–compulsive disorder: current and future directions. CNS Spectr 10:966–979.
  • DuPont RL, Rice DP, Shiraki S, Rowland CR. 1995. Economic costs of obsessive-compulsive disorder. Med Interface 8: 102–109.
  • George MS, Wasserman EM, Williams WA, Steppel J, Pascual-Leone A, Basser P, . 1996. Changes in mood and hormone levels after rapid-rate transcranial magnetic stimulation (rTMS) of the prefrontal cortex. J Neuropsychiatry Clin Neurosci 8:172–180.
  • Gershon AA, Dannon PN, Grunhaus L. 2003. Transcranial magnetic stimulation in the treatment of depression. Am J Psychiatry 160:835–845.
  • Gilbert AR, Akkal D, Almeida JR, Mataix-Cols D, Kalas C, Devlin B, . 2009. Neural correlates of symptom dimensions in pediatric obsessive-compulsive disorder: a functional magnetic resonance imaging study. J Am Acad Child Adolesc Psychiatry 48:936–944.
  • Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, . 1989. The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry 46:1006–1011.
  • Greenberg BD, George MS, Martin JD, Benjamin J, Schlaepfer TE, Altemus M, . 1997. Effect of prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: a preliminary study. Am J Psychiatry 154:867–869.
  • Greenberg BD, Ziemann U, Harmon A, Murphy DL, Wassermann EM. 1998. Decreased neuronal inhibition in cerebral cortex in obsessive-compulsive disorder on transcranial magnetic stimulation. Lancet 352:881–882.
  • Greenberg BD, Ziemann U, Corá-Locatelli G, Harmon A, Murphy DL, Keel JC, . 2000. Altered cortical excitability in obsessive-compulsive disorder. Neurology 54:142–147.
  • Haussmann A, Weis C, Marksteiner J, Hinterhuber H, Humpel C. 2000. Chronic repetitive transcranial magnetic stimulation enhances c-fos in the parietal cortex and hippocampus. Brain Res Mol Brain Res 76:355–362.
  • Hoehn-Saric R, Benkelfat C. 1994. Structural and functional brain imaging in OCD. Hollander E, Zohar J, Marazzati D. Current concepts in OCD. New York: John Wiley & Sons. 183–211.
  • Hoffman RE, Hampson M, Wu K, Anderson AW, Gore JC, Buchanan RJ, . 2007. Probing the pathophysiology of auditory/verbal hallucinations by combining functional magnetic resonance imaging and transcranial magnetic stimulation. Cereb Cortex 17:2733–2743.
  • Huppert JD, Schultz LT, Foa EB, Barlow DH, Davidson JR, Gorman JM, . 2004. Differential response to placebo among patients with social phobia, panic disorder, and obsessive-compulsive disorder. Am J Psychiatry 161:1485–1487.
  • Husain FT, Nandipati G, Braun AR, Cohen LG, Tagamets MA, Horwitz B. 2002. Stimulating transcranial magnetic stimulation during PET with a large-scale neural network model of the prefrontal cortex and the visual system. Neuroimage 15: 58–73.
  • Ipser JC, Carey P, Dhansay Y, Fakier N, Seedat S, Stein DJ. 2006. Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders. Cochrane Database Syst Rev 4: CD005473.
  • Kang DH, Kwon JS, Kim JJ, Youn T, Park HJ, Kim MS, . 2003. Brain glucose metabolic changes associated with neuropsychological improvements after 4 months of treatment in patients with obsessive–compulsive disorder. Acta Psychiatr Scand 107:291–297.
  • Kang JI, Kim CH, Namkoong K, Lee CI, Kim SJ. 2009. A randomized controlled study of sequentially applied repetitive transcranial magnetic stimulation in obsessive-compulsive disorder. J Clin Psychiatry 70:1645–1651.
  • Karno M, Golding JM, Sorenson SB, Burnam MA. 1988. The epidemiology of obsessive compulsive disorder in five US communities. Arch Gen Psychiatry 45:1094–1099.
  • Mallet L, Polosan M, Jaafari N, Baup N, Welter ML, Fontaine D, . 2008. Subthalamic nucleus stimulation in severe obsessive-compulsive disorder. New Engl J Med 359:2121–2134. Erratum in: New Engl J Med 2009;361:1027.
  • Mantovani A, Lisanby SH, Pieraccini F, Ulivelli M, Castrogiovanni P, Rossi S. 2006. Repetitive transcranial magnetic stimulation (rTMS) in the treatment of obsessive-compulsive disorder (OCD) and Tourette's syndrome (TS). Int J Neuropsychopharmacol 9:95–100.
  • Mantovani A, Leckman JF, Grantz H, King RA, Sporn AL, Lisanby SH. 2007. Repetitive transcranial magnetic stimulation of the supplementary motor area in the treatment of Tourette syndrome: report of two cases. Clin Neurophysiol 118:2314–2315.
  • Mantovani A, Simpson HB, Fallon BA, Rossi S, Lisanby SH. 2010a. Randomized sham-controlled trial of repetitive transcranial magnetic stimulation in treatment-resistant obsessive-compulsive disorder. Int J Neuropsychopharmacol 13: 217–227.
  • Mantovani A, Westin G, Hirsch J, Lisanby SH. 2010b. Functional magnetic resonance imaging guided transcranial magnetic stimulation in obsessive-compulsive disorder. Biol Psychiatry 67:e39–40.
  • Martin JL, Barbanoj MJ, Pérez V, Sacristán M. 2003. Transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder. Cochrane Database Syst Rev 3:CD003387.
  • Matsumoto R, Ichise M, Ito H, Ando T, Takahashi H, Ikoma Y, . 2010. Reduced serotonin transporter binding in the insular cortex in patients with obsessive-compulsive disorder: a [11C]DASB PET study. Neuroimage 49:121–126.
  • Mindus P, Rauch SL, Nyman H, Baer L, Edman G, Jenike MA. 1994. Capsulotomy and cingulotomy as treatments for malignant obsessive compulsive disorder: An update. Hollander E, Zohar J, Marazzati D. Current concepts in OCD. New York: John Wiley & Sons. 244–276.
  • Montagne-Larmurier A, Etard O, Razafimandimby A, Morello R, Dollfus S. 2009. Two-day treatment of auditory hallucinations by high frequency rTMS guided by cerebral imaging: a 6 month follow-up pilot study. Schizophr Res 113:77–83.
  • Nachev P, Kennard C, Husain M. 2008. Functional role of the supplementary and pre-supplementary motor areas. Nat Rev Neurosci 9:856–869.
  • Okamoto M, Dan H, Sokamoto K, Takeo K, Shimizu K, Kohno S, . 2004. Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10–20 system oriented for transcranial functional brain mapping. Neuroimage 21:99–111.
  • Pallanti S, Hollander E, Bienstock C, Koran L, Leckman J, Marazziti D, . 2002. Treatment non-response in OCD: methodological issues and operational definitions. Int J Neuropsychopharmacol 5:181–191.
  • Pallanti S, Hollander E, Goodman WK. 2004. A qualitative analysis of non response: management of treatment-refractory obsessive-compulsive disorder. J Clin Psychiatry 65(Suppl 14): 6–10.
  • Pascual-Leone A, Tormos JM, Keenan J, Tarazona F, Cañete C, Catalá MD. 1998. Study and modulation of human cortical excitability with transcranial magnetic stimulation. J Clin Neurophysiol 15:333–343.
  • Pigot M, Loo C, Sachdev P. 2008. Repetitive transcranial magnetic stimulation as treatment for anxiety disorders. Expert Rev Neurother 8:1449–1455.
  • Prasko J, Pasková B, Záleský R, Novák T, Kopecek M, Bares M, . 2006. The effect of repetitive transcranial magnetic stimulation (rTMS) on symptoms in obsessive compulsive disorder. A randomized, double blind, sham controlled study. Neuro Endocrinol Lett 27:327–332.
  • Rachid F, Bertschy G. 2006. Safety and efficacy of repetitive transcranial magnetic stimulation in the treatment of depression: a critical appraisal of the last 10 years. Neurophysiol Clin 36:157–183.
  • Rauch SL, Jenike MA, Alpert NM, Baer L, Breiter HC, Savage CR, . 1994. Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. Arch Gen Psychiatry 51:62–70.
  • Rossi S, Bartalini S, Ulivelli M, Mantovani A, Di Muro A, Goracci A, . 2005. Hypofunctioning of sensory gating mechanisms in patients with obsessive-compulsive disorder. Biol Psychiatry 57:16–20.
  • Rossi S, Hallett M, Rossini PM, Pascual-Leone A, Safety of TMS Consensus Group. 2009. Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol 120:2008–2039.
  • Ruffini C, Locatelli M, Lucca A, Benedetti F, Insacco C, Smeraldi E. 2009. Augmentation effect of repetitive transcranial magnetic stimulation over the orbitofrontal cortex in drug-resistant obsessive-compulsive disorder patients: a controlled investigation. Prim Care Companion J Clin Psychiatry 11: 226–230.
  • Sachdev PS, McBride R, Loo CK, Mitchell PB, Malhi GS, Croker VM. 2001. Right versus left prefrontal transcranial magnetic stimulation for obsessive-compulsive disorder: a preliminary investigation. J Clin Psychiatry 62:981–984.
  • Sachdev PS, McBride R, Loo C, Mitchell PM, Malhi GS, Croker V. 2002. Effects of different frequencies of transcranial magnetic stimulation (TMS) on the forced swim test model of depression in rats. Biol Psychiatry 51:474–479.
  • Sachdev PS, Loo CK, Mitchell PB, McFarquhar TF, Malhi GS. 2007. Repetitive transcranial magnetic stimulation for the treatment of obsessive compulsive disorder: a double-blind controlled investigation. Psychol Med 37:1645–1649.
  • Sack AT, Cohen Kadosh R, Schuhmann T, Moerel M, Walsh V, Goebel R. 2009. Optimizing functional accuracy of TMS in cognitive studies: a comparison of methods. J Cogn Neurosci 21:207–221.
  • Santangelo SL, Pauls DL, Goldstein JM, Faraone SV, Tsuang MT, Leckman JF. 1994. Tourette's syndrome: what are the influences of gender and comorbid obsessive-compulsive disorder? J Am Acad Child Adolesc Psychiatry 33:795–804.
  • Sarkhel S, Sinha VK, Praharaj SK. 2010. Adjunctive high- frequency right prefrontal repetitive transcranial magnetic stimulation (rTMS) was not effective in obsessive–compulsive disorder but improved secondary depression. J Anxiety Disord 24:535–539.
  • Saxena S, Rauch SL. 2000. Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. Psychiatr Clin North Am 23:563–586.
  • Saxena S, Brody AL, Schwartz JM, Baxter LR. 1998. Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder. Br J Psychiatry Suppl 35:26–37.
  • Saxena S, Brody AL, Ho ML, Alborzian S, Maidment KM, Zohrabi N, . 2002. Differential cerebral metabolic changes with paroxetine treatment of obsessive-compulsive disorder vs major depression. Arch Gen Psychiatry 59:250–261.
  • Schlaepfer TE, George MS, Mayberg H. 2010. WFSBP guidelines on brain stimulation treatments in psychiatry (WFSBP Task Force on Brain Stimulation). World J Biol Psychiatry 11:2–18.
  • Schwartz JM, Stoessel PW, Baxter LR Jr, Martin KM, Phelps ME. 1996. Systematic changes in cerebral glucose metabolic rate after successful behavior modification treatment of obsessive-compulsive disorder. Arch Gen Psychiatry 53:109–113.
  • Simpson HB, Huppert JD, Petkova E, Foa EB, Liebowitz MR. 2006. Response versus remission in obsessive-compulsive disorder. J Clin Psychiatry 67:269–276.
  • Speer AM, Kimbrell TA, Wassermann EM, D'Repella J, Willis MW, Herscovitch P, . 2000. Opposite effects of high and low frequency rTMS on regional brain activity in depressed patients. Biol Psychiatry 48:1133–1141.
  • Stein DJ, Montgomery SA, Kasper S, Tanghoj P. 2001. Predictors of response to pharmacotherapy with citalopram in obsessive-compulsive disorder. Int Clin Psychopharmacol 16:357–361.
  • Strafella AP, Paus T, Fraraccio M, Dagher A. 2003. Striatal dopamine release induced by repetitive transcranial magnetic stimulation of the human motor cortex. Brain 126: 2609–2615.
  • Swedo SE, Schapiro MB, Grady CL, Cheslow DL, Leonard HL, Kumar A, . 1989. Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. Arch Gen Psychiatry 46:518–523.
  • Szuba MP, O'Reardon JP, Rai AS, Snyder-Kastenberg J, Amsterdam JD, Gettes DR, . 2001. Acute mood and thyroid stimulating hormone effects of transcranial magnetic stimulation in major depression. Biol Psychiatry 50: 22–27.
  • Teneback CC, Nahas Z, Speer AM, Molloy M, Stallings LE, Spicer KM, . 1999. Changes in prefrontal cortex and paralimbic activity in depression following two weeks of daily left prefrontal TMS. J Neuropsychiatry Clin Neurosci 11: 426–435.
  • van den Heuvel OA, Veltman DJ, Groenewegen HJ, Cath DC, van Balkom AJ, van Hartskamp J, . 2005. Frontal-striatal dysfunction during planning in obsessive-compulsive disorder. Arch Gen Psychiatry 62:301–309.
  • Wassermann EM. 1998. Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5–7, 1996. Electroencephalogr Clin Neurophysiol 108:1–16.
  • Weissman MM, Bland RC, Canino GJ, Greenwald S, Hwu HG, Lee CK, . 1994. The cross national epidemiology of obsessive compulsive disorder. J Clin Psychiatry 55(Suppl): 5–10.
  • Whiteside SP, Port JD, Abramowitz JS. 2004. A meta-analysis of functional neuroimaging in obsessive-compulsive disorder. Psychiatry Res 132:69–79.
  • Yücel M, Harrison BJ, Wood SJ, Fornito A, Wellard RM, Pujol J, . 2007. Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder. Arch Gen Psychiatry 64:946–955.

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