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Research Article

Frontopolar cortical inefficiency may underpin reward and working memory dysfunction in bipolar disorder

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Pages 605-615 | Received 26 Nov 2010, Accepted 27 Apr 2011, Published online: 03 Aug 2011

References

  • Adler CM, Holland SK, Schmithorst V, Tuchfarber MJ, Strakowski SM. 2004. Changes in neuronal activation in patients with bipolar disorder during performance of a working memory task. Bipolar Disord 6:540–549.
  • American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders. 4th. Washington, DC: American Psychiatric Association.
  • Bechara A. 2005. Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. Nat Neurosci 8:1458–1463.
  • Bechara A, Damasio AR, Damasio H, Anderson SW. 1994. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50:7–15.
  • Bechara A, Damasio H, Tranel D, Anderson WS. 1998. Dissociation of working memory from decision making within the human prefrontal cortex. J Neurosci 18:426–437.
  • Bezchlibnyk-Butler KZ, Jeffries JJ. 2000. Clinical handbook of psychotropic drugs. 10th. Seattle: Hogrefe & Huber Publishers. 84–88.
  • Brown JW, Braver TS. 2005. Learned predictions of error likelihood in the anterior cingulate cortex. Science 307:1118–1121.
  • Callicott JH, Mattay VS, Verchinski BA, Marenco S, Egan MF, Weinberger DR. 2003. Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down. Am J Psychiatry 160:2209–2215.
  • Chang K, Adleman NE, Dienes K, Simeonova DI, Menon V, Reiss A. 2004. Anomalous prefrontal-subcortical activation in familial pediatric bipolar disorder: a functional magnetic resonance imaging investigation. Arch Gen Psychiatry 61:781–792.
  • Critchley HD, Elliott R, Mathias CJ, Dolan RJ. 2000. Neural activity relating to generation and representation of galvanic skin conductance responses: a functional magnetic resonance imaging study. J Neurosci 20:3033–3040.
  • Davidson RJ, Irwin W. 1999. The functional neuroanatomy of emotion and affective style. Trends Cogn Sci 3:11–21.
  • Drapier D, Surguladze S, Marshall N, Schulze K, Fern A, Hall MH, . 2008. Genetic liability for bipolar disorder is characterized by excess frontal activation in response to a working memory task. Biol Psychiatry 64:513–520.
  • Duncan J, Seitz RJ, Kolodny J, Bor D, Herzog H, Ahmed A, . 2000. A neural basis for general intelligence. Science 289:457–460.
  • Elliott R, Friston KJ, Dolan RJ. 2000. Dissociable neural responses in human reward systems. J Neurosci 20:6159–6165.
  • Ernst M, Paulus MP. 2005. Neurobiology of decision making: a selective review from a neurocognitive and clinical perspective. Biol Psychiatry 58:597–604.
  • Fellows LK, Farah MJ. 2005. Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. Cereb Cortex 15:58–63.
  • First MB, Spitzer RL, Gibbon M, Williams JBW. 2002a. Structured clinical interview for DSM-IV-TR Axis I disorders, research version, patient edition (SCID-I/P). New York: Biometrics Research, New York State Psychiatric Institute.
  • First MB, Spitzer RL, Gibbon M, Williams JBW. 2002b. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition. (SCID-I/NP). New York: Biometrics Research, New York State Psychiatric Institute.
  • Fletcher PC, Henson RN. 2001. Frontal lobes and human memory: insights from functional neuroimaging. Brain 124:849–881.
  • Frangou S. 2009. Risk and resilience in bipolar disorder: rationale and design of the Vulnerability to Bipolar Disorders Study (VIBES). Biochem Soc Trans 37:1085–1089.
  • Frangou S, Kington J, Raymont V, Shergill SS. 2008. Examining ventral and dorsal prefrontal function in bipolar disorder: a functional magnetic resonance imaging study. Eur Psychiatry 23:300–308.
  • Fukui H, Murai T, Fukuyama H, Hayashi T, Hanakawa T. 2005. Functional activity related to risk anticipation during performance of the Iowa Gambling Task. NeuroImage 24:253–259.
  • Fuster JM. 2001. The prefrontal cortex – an update: time is of the essence. Neuron 30:319–333.
  • Green MJ, Cahill CM, Malhi GS. 2007. The cognitive and neurophysiological basis of emotion dysregulation in bipolar disorder. J Affect Disord 103:29–42.
  • Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56–62.
  • Hooper CJ, Luciana M, Conklin HM, Yarger RS. 2004. Adolescents’ performance on the Iowa Gambling Task: implications for the development of decision making and ventromedial prefrontal cortex. Dev Psychol 40:1148–1158.
  • Karlsgodt KH, Glahn DC, van Erp TG, Therman S, Huttunen M, Manninen M, . 2007. The relationship between performance and fMRI signal during working memory in patients with schizophrenia, unaffected co-twins, and control subjects. Schizophr Res 89:191–197.
  • Kempton MJ, Haldane M, Jogia J, Grasby PM, Collier D, Frangou S. 2009. Dissociable brain structural changes associated with predisposition, resilience, and disease expression in bipolar disorder. J Neurosci 29:10863–10868.
  • Kim MA, Tura E, Potkin SG, Fallon JH, Manoach DS, Calhoun VD, . 2010. Working memory circuitry in schizophrenia shows widespread cortical inefficiency and compensation. Schizophr Res 117:42–51.
  • Koechlin E, Hyafil A. 2007. Anterior prefrontal function and the limits of human-decision making. Science 318:594–598.
  • Konishi S, Nakajima K, Uchida I, Kikyo H, Kameyama M, Miyashita Y. 1999. Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI. Brain 122:981–991.
  • Krüger S, Seminowicz D, Goldapple K, Kennedy SH, Mayberg HS. 2003. State and trait influences on mood regulation in bipolar disorder: blood flow differences with an acute mood challenge. Biol Psychiatry 54:1274–1283.
  • Lawrence NS, Jollant F, O'Daly O, Zelaya F, Phillips ML. 2009. Distinct roles of prefrontal cortical subregions in the Iowa Gambling Task. Cereb Cortex 19:1134–1143.
  • Lukoff D, Nuechterlien K, Ventura J. 1986. Manual for the expanded Brief Psychiatric Rating Scale. Schizophr Bull 12:594–608.
  • Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. 2003. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19: 1233–1239.
  • Manoach DS. 2003. Prefrontal cortex dysfunction during working memory performance in schizophrenia: reconciling discrepant findings. Schizophr Res 60:285–298.
  • Marklund P, Fransson P, Cabeza R, Petersson KM, Ingvar M, Nyberg L. 2007. Sustained and transient neural modulations in prefrontal cortex related to declarative long-term memory, working memory, and attention. Cortex. 2007;43:22–37.
  • McCoy AN, Platt ML, 2005. Risk-sensitive neurons in macaque posterior cingulate cortex. Nat Neurosci 8: 1220–1227.
  • McDermott KB, Ojemann JG, Petersen SE, Ollinger JM, Snyder AZ, Akbudak E, . 1999. Direct comparison of episodic encoding and retrieval of words: an event-related fMRI study. Memory 7:661–678.
  • Monks PJ, Thompson JM, Bullmore ET, Suckling J, Brammer MJ, Williams SC, . 2004. A functional MRI study of working memory task in euthymic bipolar disorder: evidence for task-specific dysfunction. Bipolar Disord 6:550–564.
  • Northoff G, Grimm S, Boeker H, Schmidt C, Bermpohl F, Heinzel A, . 2006. Affective judgment and beneficial decision making: ventromedial prefrontal activity correlates with performance in the Iowa Gambling Task. Hum Brain Mapp 27:572–587.
  • Owen AM, McMillan KM, Laird AR, Bullmore E. 2005. N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies. Hum Brain Mapp 25:46–59.
  • Paulus MP, Hozack N, Frank L, Brown GG. 2002. Error rate and outcome predictability affect neural activation in prefrontal cortex and anterior cingulate during decision-making. Neuroimage 15:836–846.
  • Paus T, Koski L, Caramanos Z, Westbury C. 1998. Regional differences in the effects of task difficulty and motor output on blood flow response in the human anterior cingulate cortex: a review of 107 PET activation studies. Neuroreport 9:R37–47.
  • Petrides M, Pandya DN. 2007. Efferent association pathways from the rostral prefrontal cortex in the macaque monkey. J Neurosci 27:11573–11586.
  • Phillips ML, Ladouceur CD, Drevets WC. 2008a. A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder. Mol Psychiatry 13:829–857.
  • Phillips ML, Travis MJ, Fagiolini A, Kupfer DJ. 2008b. Medication effects in neuroimaging studies of bipolar disorder. Am J Psychiatry 165:313–320.
  • Pochon JB, Levy R, Fossati P, Lehericy S, Poline JB, Pillon B, . 2002. The Neural system that bridges reward and cognition in humans: an fMRI study. Proc Natl Acad Sci USA 99:5669–5674.
  • Pochon JB, Riis J, Sanfey AG, Nystrom LE, Cohen JD. 2008. Functional imaging of decision conflict. J Neurosci 28:3468–3473.
  • Reavis R, Overman WH. 2001. Adult sex differences on a decision-making task previously shown to depend on the orbital prefrontal cortex. Behav Neurosci 115:196–206.
  • Rolls ET, Grabenhorst F. 2008. The orbitofrontal cortex and beyond: from affect to decision-making. Prog Neurobiol 86:216–244.
  • Rubinsztein JS, Fletcher PC, Rogers RD, Ho LW, Aigbirhio FI, Paykel ES, . 2001. Decision-making in mania: a PET study. Brain 124:2550–2563.
  • Stefanopoulou E, Manoharan A, Landau S, Geddes JR, Goodwin G, Frangou S. 2009. Cognitive functioning in patients with affective disorders and schizophrenia: a meta-analysis. Int Rev Psychiatry 21:336–356.
  • Strakowski SM, Delbello MP, Adler CM. 2005. The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings. Mol Psychiatry 10:105–116.
  • Thermenos HW, Goldstein JM, Milanovic SM, Whitfield-Gabrieli S, Makris N, Laviolette P, . 2010. An fMRI study of working memory in persons with bipolar disorder or at genetic risk for bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 153B:120–131.
  • Torres IJ, Boudreau VG, Yatham LN. 2007. Neuropsychological functioning in euthymic bipolar disorder: a meta-analysis. Acta Psychiatr Scand Suppl 434:17–26.
  • Turnbull OH, Evans CE, Bunce A, Carzolio B, O'connor J. 2005. Emotion-based learning and central executive resources: an investigation of intuition and the Iowa Gambling Task. Brain Cogn 57:244–247.
  • Wechsler D. 1981. Wechsler adult intelligence scale-revised (WAIS-R) manual. New York: Psychological Corporation.
  • Volz KG, Schubotz RI, von Cramon DY, 2003. Predicting events of varying probability: uncertainty investigated by fMRI. Neuroimage 19:271–280.
  • Young RC, Biggs JT, Ziegler VE, Meyer DA. 1978. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 133:429–435.

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