731
Views
116
CrossRef citations to date
0
Altmetric
Research Article

Influence of size, surface area and microporosity on the in vitro cytotoxic activity of amorphous silica nanoparticles in different cell types

, , , , , , , , , & show all
Pages 307-318 | Received 19 Sep 2009, Accepted 23 Mar 2010, Published online: 14 May 2010

References

  • Auffan M, Rose J, Bottero JY, Lowry GV, Jolivet JP, Wiesner MR. 2009. Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective. Nat Nanotechnol 4(10):634–641.
  • Balbus JM, Maynard AD, Colvin VL, Castranova V, Daston GP, Denison RA, Dreher KL, Goering PL, Goldberg AM, Kulinowski KM, Monteiro-Riviere NA, Oberdörster G, Omenn GS, Pinkerton KE, Ramos KS, Rest KM, Sass JB, Silbergeld EK, Wong BA. 2007. Meeting report: Hazard assessment for nanoparticles – report from an interdisciplinary workshop. Environ Health Perspect 115(11):1654–1659.
  • Brunauer S, Emmett PH, Teller E. 1938. Adsorption of gases in multimolecular layers. J Am Chem Soc 60(2):309–319.
  • Buono C, Anzinger JJ, Amar M, Kruth HS. 2009. Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions. J Clin Invest 119(5):1373–1381.
  • Davis TM, Snyder MA, Krohn JE, Tsapatsis M. 2006. Nanoparticles in lysine-silica sols. Chemistry of Materials 18(25):5814–5816.
  • Depasse J. 1978. Interaction between silica and hydrophobic cations. Br J Ind Med 35(1):32–34.
  • Di Pasqua AJ, Sharma KK, Shi YL, Toms BB, Ouellette W, Dabrowiak JC, Asefa T. 2008. Cytotoxicity of mesoporous silica nanomaterials. J Inorg Biochem 102(7):1416–1423.
  • Diociaiuti M, Bordi F, Gataleta L, Baldo G, Crateri P, Paoletti L. 1999. Morphological and functional alterations of human erythrocytes induced by SiO2 particles: An electron microscopy and dielectric spectroscopy study. Environ Res 80(3):197–207.
  • Duffin R, Tran L, Brown D, Stone V, Donaldson K. 2007. Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: Highlighting the role of particle surface area and surface reactivity. Inhal Toxicol 19(10):849–856.
  • Fenoglio I, Greco G, Tomatis M, Muller J, Raymundo-Pinero E, Beguin F, Fonseca A, Nagy JB, Lison D, Fubini B. 2008. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: Physicochemical aspects. Chem Res Toxicol 21(9):1690–1697.
  • Fubini B. 1998. Surface chemistry and quartz hazard. Ann Occup Hyg 42(8):521–530.
  • Hamilton RF Jr, Thakur SA, Mayfair JK, Holian A. 2006. MARCO mediates silica uptake and toxicity in alveolar macrophages from C57BL/6 mice. J Biol Chem 281(45):34218–34226.
  • Holsapple MP, Farland WH, Landry TD, Monteiro-Riviere NA, Carter JM, Walker NJ, Thomas KV. 2005. Research strategies for safety evaluation of nanomaterials. Part II: Toxicological and safety evaluation of nanomaterials, current challenges and data needs. Toxicol Sci 88(1):12–17.
  • Iler RK. 1979. The chemistry of silica: Solubility, polymerization, colloid and surface properties and biochemistry. New York: Wiley & Sons.
  • Jaroniec M, Kruk M, Olivier JP. 1999. Standard nitrogen adsorption data for characterization of nanoporous silicas. Langmuir 15(16):5410–5413.
  • Kanno S, Furuyama A, Hirano S. 2007. A murine scavenger receptor MARCO recognizes polystyrene nanoparticles. Toxicol Sci 97(2):398–406.
  • Lison D, Lardot C, Huaux F, Zanetti G, Fubini B. 1997. Influence of particle surface area on the toxicity of insoluble manganese dioxide dusts. Arch Toxicol 71(12):725–729.
  • Lison D, Thomassen LC, Rabolli V, Gonzalez L, Napierska D, Seo JW, Kirsch-Volders M, Hoet P, Kirschhock CE, Martens JA. 2008. Nominal and effective dosimetry of silica nanoparticles in cytotoxicity assays. Toxicol Sci 104(1):155–162.
  • Lu S, Duffin R, Poland C, Daly P, Murphy F, Drost E, MacNee W, Stone V, Donaldson K. 2009. Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation. Environ Health Perspect 117(2):241–247.
  • Marsh M, McMahon HT. 1999. The structural era of endocytosis. Science 285(5425):215–220.
  • Monteiller C, Tran L, MacNee W, Faux S, Jones A, Miller B, Donaldson K. 2007. The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: The role of surface area. Occup Environ Med 64(9):609–615.
  • Muller J, Huaux F, Fonseca A, Nagy JB, Moreau N, Delos M, Raymundo-Pinero E, Beguin F, Kirsch-Volders M, Fenoglio I, Fubini B, Lison D. 2008. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: Toxicological aspects. Chem Res Toxicol 21(9):1698–1705.
  • Murdock RC, Braydich-Stolle L, Schrand AM, Schlager JJ, Hussain SM. 2008. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicol Sci 101(2):239–253.
  • Napierska D, Thomassen LC, Rabolli V, Lison D, Gonzalez L, Kirsch-Volders M, Martens JA, Hoet PH. 2009. Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. Small 5(7):846–853.
  • Nash T, Allison AC, Harington JS. 1966. Physico-chemical properties of silica in relation to its toxicity. Nature 210(5033):259–261.
  • Nolan RP, Langer AM, Harington JS, Oster G, Selikoff IJ. 1981. Quartz hemolysis as related to its surface functionalities. Environ Res 26(2):503–520.
  • Oberdörster G, Ferin J, Lehnert BE. 1994. Correlation between particle size, in vivo particle persistence, and lung injury. Environ Health Perspect 102(Suppl. 5):173–179.
  • Petushkov A, Intra J, Graham JB, Larsen SC, Salem AK. 2009. Effect of crystal size and surface functionalization on the cytotoxicity of silicalite-1 nanoparticles. Chem Res Toxicol 22(7):1359–1368.
  • Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WA, Seaton A, Stone V, Brown S, MacNee W, Donaldson K. 2008. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3(7):423–428.
  • Razzaboni BL, Bolsaitis P. 1990. Evidence of an oxidative mechanism for the hemolytic activity of silica particles. Environ Health Perspect 87:337–341.
  • Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA. 2007. Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes. J Invest Dermatol 127(1):143–153.
  • Sager TM, Castranova V. 2009. Surface area of particle administered versus mass in determining the pulmonary toxicity of ultrafine and fine carbon black: comparison to ultrafine titanium dioxide. Part Fibre Toxicol 6:15.
  • Sager TM, Kommineni C, Castranova V. 2008. Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: Role of particle surface area. Part Fibre Toxicol 5:17.
  • Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R. 2008. Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci USA 105(21):7387–7392.
  • Slowing II, Vivero-Escoto JL, Wu CW, Lin VS. 2008. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv Drug Deliv Rev 60(11):1278–1288.
  • Slowing II, Wu CW, Vivero-Escoto JL, Lin VS. 2009. Mesoporous silica nanoparticles for reducing hemolytic activity towards mammalian red blood cells. Small 5(1):57–62.
  • Stalder K, Stober W. 1965. Haemolytic activity of suspensions of different silica modifications and inert dusts. Nature 207(999):874–875.
  • Stöber W, Fink A, Bohn E. 1968. Controlled growth of monodisperse silica spheres in the micron size range. Journal of Colloid and Interface Science 26(1):62–69.
  • Suggs JE, Madden MC, Friedman M, Edgell CJ. 1986. Prostacyclin expression by a continuous human cell line derived from vascular endothelium. Blood 68:825–829.
  • Tao Z, Morrow MP, Asefa T, Sharma KK, Duncan C, Anan A, Penefsky HS, Goodisman J, Souid AK. 2008. Mesoporous silica nanoparticles inhibit cellular respiration. Nano Lett 8(5):1517–1526.
  • Thomassen LC, Aerts A, Rabolli V, Lison D, Kirsch-Volders M, Gonzalez L, Napierska D, Hoet PH, Kirschhock CE, Martens JA. 2010. Synthesis and characterization of stable monodisperse silica nanoparticle sols for in vitro cytotoxicity testing. Langmuir 26(1):328–335.
  • Tran CL, Buchanan D, Cullen RT, Searl A, Jones AD, Donaldson K. 2000. Inhalation of poorly soluble particles. II. Influence of particle surface area on inflammation and clearance. Inhal Toxicol 12(12):1113–1126.
  • van-Blaaderen A, Kentgens APM. 2007. Particle morphology and chemical microstructure of colloidal silica spheres made from alkoxysilanes. J No-Crystalline Solids 149:149–161.
  • Warheit DB, Webb TR, Colvin VL, Reed KL, Sayes CM. 2007. Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: Toxicity is not dependent upon particle size but on surface characteristics. Toxicol Sci 95(1):270–280.
  • Warheit DB, Webb TR, Sayes CM, Colvin VL, Reed KL. 2006. Pulmonary instillation studies with nanoscale TiO2 rods and dots in rats: Toxicity is not dependent upon particle size and surface area. Toxicol Sci 91(1):227–236.
  • Waters KM, Masiello LM, Zangar RC, Tarasevich BJ, Karin NJ, Quesenberry RD, Bandyopadhyay S, Teeguarden JG, Pounds JG, Thrall BD. 2009. Macrophage responses to silica nanoparticles are highly conserved across particle sizes. Toxicol Sci 107(2):553–569.
  • Wittmaack K. 2007. In search of the most relevant parameter for quantifying lung inflammatory response to nanoparticle exposure: Particle number, surface area, or what? Environ Health Perspect 115(2):187–194.
  • Yacobi NR, Malmstadt N, Fazlollahi F, Demaio L, Marchelletta R, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. 2009. Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles. Am J Respir Cell Mol Biol 42(5):604–614.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.