Oral ingestion of silver nanoparticles induces genomic instability and DNA damage in multiple tissues

References

• Al-Tassan N, Chmiel NH, Maynard J, Fleming N, Livingston AL, Williams GT, et al. 2002. Inherited variants of MYH associated with somatic G:C–>T: A mutations in colorectal tumors. Nat Genet 30:227–32
   PubMed Web of Science ®Google Scholar
• Asharani P, Sethu S, Lim HK, Balaji G, Valiyaveettil S, Hande MP. 2012. Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells. Genome Integr 3:2 (1–14)
   PubMedGoogle Scholar
• Benn TM, Westerhoff P. 2008. Nanoparticle silver released into water from commercially available sock fabrics. Environ Sci Technol 42:4133–9
   PubMed Web of Science ®Google Scholar
• Blaser SA, Scheringer M, Macleod M, Hungerbuhler K. 2008. Estimation of cumulative aquatic exposure and risk due to silver: contribution of nano-functionalized plastics and textiles. Sci Total Environ 390:396–409
   PubMed Web of Science ®Google Scholar
• Burkovics P, Hajdu I, Szukacsov V, Unk I, Haracska L. 2009. Role of PCNA-dependent stimulation of 3′-phosphodiesterase and 3′-5′ exonuclease activities of human Ape2 in repair of oxidative DNA damage. Nucleic Acids Res 37:4247–55
   PubMed Web of Science ®Google Scholar
• Cardoso J, Molenaar L, de Menezes RX, van Leerdam M, Rosenberg C, Moslein G, et al. 2006. Chromosomal instability in MYH- and APC-mutant adenomatous polyps. Cancer Res 66:2514–19
   Google Scholar
• Chaloupka K, Malam Y, Seifalian AM. 2010. Nanosilver as a new generation of nanoproduct in biomedical applications. Trends Biotechnol 28:580–8
   PubMed Web of Science ®Google Scholar
• Church J, Heald B, Burke C, Kalady M. 2012. Understanding MYH-associated neoplasia. Dis Colon Rectum 55:359–62
   Google Scholar
• Elsaesser A, Howard CV. 2012. Toxicology of nanoparticles. Adv Drug Deliv Rev 64:129–37
   PubMed Web of Science ®Google Scholar
• Fanning E, Klimovich V, Nager AR. 2006. A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res 34:4126–37
   PubMed Web of Science ®Google Scholar
• Geranio L, Heuberger M, Nowack B. 2009. The behavior of silver nanotextiles during washing. Environ Sci Technol 43:8113–18
   PubMed Web of Science ®Google Scholar
• Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, et al. 2007. Patterns of somatic mutation in human cancer genomes. Nature 446:153–8
   PubMed Web of Science ®Google Scholar
• Hahm SH, Chung JH, Agustina L, Han SH, Yoon IS, Park JH, et al. 2012. Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells. Oncol Lett 4:1203–8
   Google Scholar
• Hahm SH, Park JH, Ko SI, Lee YR, Chung IS, Chung JH, et al. 2011. Knock-down of human MutY homolog (hMYH) decreases phosphorylation of checkpoint kinase 1 (Chk1) induced by hydroxyurea and UV treatment. BMB Rep 44:352–57
   Google Scholar
• Hegde ML, Hazra TK, Mitra S. 2008. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res 18:27–47
   PubMed Web of Science ®Google Scholar
• Huang Y. 2011. Nanosilver migarated into food-simulating solutions from commercially available food fresh containers. Pack Technol Sci 24:291–7
   Web of Science ®Google Scholar
• Kim B, Park CS, Murayama M, Hochella MF. 2010a. Discovery and characterization of silver sulfide nanoparticles in final sewage sludge products. Environ Sci Technol 44:7509–14
   PubMed Web of Science ®Google Scholar
• Kim JS, Sung JH, Ji JH, Song KS, Lee JH, Kang CS, Yu IJ. 2011. In vivo genotoxicity of silver nanoparticles after 90-day silver nanoparticle inhalation exposure. Saf Health Work 2:34–8
   PubMedGoogle Scholar
• Kim S, Ryu DY. 2013. Silver nanoparticle-induced oxidative stress, genotoxicity and apoptosis in cultured cells and animal tissues. J Appl Toxicol 33:78–89
   PubMed Web of Science ®Google Scholar
• Kim YS, Kim JS, Cho HS, Rha DS, Kim JM, Park JD, et al. 2008. Twenty-eight-day oral toxicity, genotoxicity, and gender-related tissue distribution of silver nanoparticles in Sprague–Dawley rats. Inhal Toxicol 20:575–83
   PubMed Web of Science ®Google Scholar
• Kim YS, Song MY, Park JD, Song KS, Ryu HR, Chung YH, et al. 2010b. Subchronic oral toxicity of silver nanoparticles. Part Fibre Toxicol 7:20 (1–11)
   PubMed Web of Science ®Google Scholar
• Li X, Lenhart JJ, Walker HW. 2012. Aggregation kinetics and dissolution of coated silver nanoparticles. Langmuir 28:1095–104
   PubMed Web of Science ®Google Scholar
• Lin S, Cheng Y, Liu J, Wiesner MR. 2012. Polymeric coatings on silver nanoparticles hinder autoaggregation but enhance attachment to uncoated surfaces. Langmuir 28:4178–86
   PubMed Web of Science ®Google Scholar
• Loeschner K, Hadrup N, Qvortrup K, Larsen A, Gao X, Vogel U, Mortensen A, et al. 2011. Distribution of silver in rats following 28 days of repeated oral exposure to silver nanoparticles or silver acetate. Part Fibre Toxicol 8:18 (1–15)
   PubMed Web of Science ®Google Scholar
• Lorenz C, Windler L, von Goetz N, Lehmann RP, Schuppler M, Hungerbuhler K, et al. 2012. Characterization of silver release from commercially available functional (nano)textiles. Chemosphere 89:817–24
   PubMed Web of Science ®Google Scholar
• Lowry GV, Espinasse BP, Badireddy AR, Richardson CJ, Reinsch BC, Bryant LD, et al. 2012. Long-term transformation and fate of manufactured ag nanoparticles in a simulated large scale freshwater emergent wetland. Environ Sci Technol 46:7027–36
   PubMed Web of Science ®Google Scholar
• Luncsford PJ, Chang DY, Shi G, Bernstein J, Madabushi A, Patterson DN, et al. 2010. A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. J Mol Biol 403:351–70
   Google Scholar
• Maillard JY, Hartemann P. 2013. Silver as an antimicrobial: facts and gaps in knowledge. Crit Rev Microbiol 39:373–383
   Google Scholar
• Maneewattanapinyo P, Banlunara W, Thammacharoen C, Ekgasit S, Kaewamatawong T. 2011. An evaluation of acute toxicity of colloidal silver nanoparticles. J Vet Med Sci 73:1417–23
   PubMed Web of Science ®Google Scholar
• Navarro E, Baun A, Behra R, Hartmann NB, Filser J, Miao AJ, et al. 2008. Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi. Ecotoxicology 17:372–86
   PubMed Web of Science ®Google Scholar
• Obe G, Pfeiffer P, Savage JR, Johannes C, Goedecke W, Jeppesen P, et al. 2002. Chromosomal aberrations: formation, identification and distribution. Mutat Res 504:17–36
   PubMed Web of Science ®Google Scholar
• Oka S, Ohno M, Tsuchimoto D, Sakumi K, Furuichi M, Nakabeppu Y. 2008. Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs. EMBO J 27:421–32
   PubMedGoogle Scholar
• Park EJ, Bae E, Yi J, Kim Y, Choi K, Lee SH, et al. 2010. Repeated-dose toxicity and inflammatory responses in mice by oral administration of silver nanoparticles. Environ Toxicol Pharmacol 30:162–8
   PubMed Web of Science ®Google Scholar
• Park K, Park EJ, Chun IK, Choi K, Lee SH, Yoon J, Lee BC. 2011. Bioavailability and toxicokinetics of citrate-coated silver nanoparticles in rats. Arch Pharm Res 34:153–8
   PubMed Web of Science ®Google Scholar
• Parker AR, Eshleman JR. 2003. Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis. Cell Mol Life Sci 60:2064–83
   PubMedGoogle Scholar
• PEN. 2013. Consumer products inventory. The project on emerging nanotechnologies (PEN). Avaialble from: http://www.nanotechproject.org/inventories/consumer/ [last accessed 10 Jan 2014]
   Google Scholar
• Piao MJ, Kang KA, Lee IK, Kim HS, Kim S, Choi JY, et al. 2011. Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis. Toxicol Lett 201:92–100
   PubMed Web of Science ®Google Scholar
• Reliene R, Bishop AJ, Aubrecht J, Schiestl RH. 2004a. In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol Biol 262:125–39
   PubMedGoogle Scholar
• Reliene R, Fischer E, Schiestl RH. 2004b. Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res 64:5148–53
   PubMed Web of Science ®Google Scholar
• Reliene R, Pollard JM, Sobol Z, Trouiller B, Gatti RA, Schiestl RH. 2009. N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals. Mutat Res 665:37–43
   PubMed Web of Science ®Google Scholar
• Reliene R, Schiestl RH. 2006. Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis 27:240–4
   PubMed Web of Science ®Google Scholar
• Reliene R, Yamamoto ML, Rao PN, Schiestl RH. 2010. Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg. Cancer Res 70:9703–10
   PubMed Web of Science ®Google Scholar
• Rogers KR, Bradham K, Tolaymat T, Thomas DJ, Hartmann T, Ma L, Williams A. 2012. Alterations in physical state of silver nanoparticles exposed to synthetic human stomach fluid. Sci Total Environ 420:334–9
   PubMed Web of Science ®Google Scholar
• Shannahan JH, Lai X, Ke PC, Podila R, Brown JM, Witzmann FA. 2013. Silver nanoparticle protein corona composition in cell culture media. PLoS One 8:e74001
   PubMed Web of Science ®Google Scholar
• Tejamaya M, Romer I, Merrifield RC, Lead JR. 2012. Stability of citrate, PVP, and PEG coated silver nanoparticles in ecotoxicology media. Environ Sci Technol 46:7011–17
   PubMed Web of Science ®Google Scholar
• Terdiman JP. 2009. MYH-associated disease: attenuated adenomatous polyposis of the colon is only part of the story. Gastroenterology 137:1883–6
   Google Scholar
• Tiwari DK, Jin T, Behari J. 2011. Dose-dependent in-vivo toxicity assessment of silver nanoparticle in Wistar rats. Toxicol Mech Methods 21:13–24
   PubMed Web of Science ®Google Scholar
• Tolaymat TM, El Badawy AM, Genaidy A, Scheckel KG, Luxton TP, Suidan M. 2010. An evidence-based environmental perspective of manufactured silver nanoparticle in syntheses and applications: a systematic review and critical appraisal of peer-reviewed scientific papers. Sci Total Environ 408:999–1006
   PubMed Web of Science ®Google Scholar
• Tomkinson AE, Chen L, Dong Z, Leppard JB, Levin DS, Mackey ZB, Motycka TA. 2001. Completion of base excision repair by mammalian DNA ligases. Prog Nucleic Acid Res Mol Biol 68:151–64
   PubMed Web of Science ®Google Scholar
• van der Zande M, Vandebriel RJ, Van Doren E, Kramer E, Herrera Rivera Z, Serrano-Rojero CS, et al. 2012. Distribution, elimination, and toxicity of silver nanoparticles and silver ions in rats after 28-day oral exposure. ACS Nano 6:7427–42
   PubMed Web of Science ®Google Scholar
• Volker C, Oetken M, Oehlmann J. 2013. The biological effects and possible modes of action of nanosilver. Rev Environ Contam Toxicol 223:81–106
   PubMed Web of Science ®Google Scholar
• Walkey CD, Chan WC. 2012. Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment. Chem Soc Rev 41:2780–99
   PubMed Web of Science ®Google Scholar
• Westbrook AM, Wei B, Braun J, Schiestl RH. 2009. Intestinal mucosal inflammation leads to systemic genotoxicity in mice. Cancer Res 69:4827–34
   PubMed Web of Science ®Google Scholar
• Willis J, Patel Y, Lentz BL, Yan S. 2013. APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress. Proc Natl Acad Sci USA 110:10592–7
   Google Scholar
• Xie Y, Yang H, Cunanan C, Okamoto K, Shibata D, Pan J, et al. 2004. Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res 64:3096–102
   PubMed Web of Science ®Google Scholar
• Yang W, Shen C, Ji Q, An H, Wang J, Liu Q, Zhang Z. 2009. Food storage material silver nanoparticles interfere with DNA replication fidelity and bind with DNA. Nanotechnology 20:085102 (1–7)
   PubMed Web of Science ®Google Scholar