Advanced search
Publication Cover
Nanotoxicology Volume 9, 2015 - Issue 4
Submit an article Journal homepage
416
Views
22
CrossRef citations to date
0
Altmetric
Original Article

Toxic responses in rat embryonic cells to silver nanoparticles and released silver ions as analyzed via gene expression profiles and transmission electron microscopy

Liming XuInstitute for Medical Device Control, National Institutes for Food and Drug Control, Temple of Heaven, Beijing, People's Republic of China, ;School of Information and Engineering, Wenzhou Medical University, Wenzhou, People's Republic of China, ;Baotou Medical College, Baotou, People's Republic of China, Correspondence[email protected]
,
Chang ShiBeijing Institute of Pharmacology and Toxicology, National Beijing Center for Drug Safety Evaluation and Research, Beijing, People's Republic of China,
,
Anliang ShaoInstitute for Medical Device Control, National Institutes for Food and Drug Control, Temple of Heaven, Beijing, People's Republic of China,
,
Xuefei LiBaotou Medical College, Baotou, People's Republic of China, ;The First Affiliated Hospital, Baotou Medical College, Baotou, People's Republic of China,
,
Xiang ChengInstitute for Medical Device Control, National Institutes for Food and Drug Control, Temple of Heaven, Beijing, People's Republic of China, ;School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, People's Republic of China, and
,
Rigao DingBeijing Institute of Pharmacology and Toxicology, National Beijing Center for Drug Safety Evaluation and Research, Beijing, People's Republic of China,
,
Gang WuThe First Affiliated Hospital, Baotou Medical College, Baotou, People's Republic of China,
&
Laisheng Lee ChouGoldman School of Dental Medicine, Boston University, Boston, MA, USA
 show all
Pages 513-522 | Received 09 Mar 2014, Accepted 22 Jul 2014, Published online: 14 Aug 2014

References

  • Ahamed M, Alsalhi MS, Siddiqui MK. 2010. Silver nanoparticle applications and human health. Clin Chim Acta 411:1841–8
  • Asare N, Instanes C, Sandberg WJ, Refsnes M, Schwarze P, Kruszewski M, Brunborg G. 2012. Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells. Toxicology 291:65–72
  • AshaRani PV, Low Kah Mun G, Hande MP, Valiyaveettil S. 2009. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 3:279–90
  • Böhmert L, Niemann B, Thünemann AF, Lampen A. 2012. Cytotoxicity of peptide-coated silver nanoparticles on the human intestinal cell line Caco-2. Arch Toxicol 86:1107–15
  • Chairuangkitti P, Lawanprasert S, Roytrakul S, Aueviriyavit S, Phummiratch D, Kulthong K, et al. 2013. Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways. Toxicol In Vitro 27:330–8
  • Choi JE, Kim S, Ahn JH, Youn P, Kang JS, Park K, et al. 2010. Induction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafish. Aquat Toxicol 100:151–9
  • Flower NA, Brabu B, Revathy M, Gopalakrishnan C, Raja SV, Murugan SS, Kumaravel TS. 2012. Characterization of synthesized silver nanoparticles and assessment of its genotoxicity potentials using the alkaline comet assay. Mutat Res 742:61–5
  • Gaiser BK, Hirn S, Kermanizadeh A, Kanase N, Fytianos K, Wenk A, et al. 2013. Effects of silver nanoparticles on the liver and hepatocytes in vitro. Toxicol Sci 131:537–47
  • Kim HR, Kim MJ, Lee SY, Oh SM, Chung KH. 2011. Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells. Mutat Res 726:129–35
  • Lara HH, Garza-Treviño EN, Ixtepan-Turrent L, Singh DK. 2011. Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds. J Nanobiotechnol 9:30–7
  • Li X, Xu L, Shao A, Wu G, Hanagata N. 2013. Cytotoxic and genotoxic effects of silver nanoparticles on primary Syrian hamster embryo (SHE) cells. J Nanosci Nanotechnol 13:161–70
  • Li B, Ding L, Li W, Story MD, Pace BS. 2012. Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation. BMC Genomics 13:153–70
  • Liu Y, Guan W, Ren G, Yang Z. 2012. The possible mechanism of silver nanoparticle impact on hippocampal synaptic plasticity and spatial cognition in rats. Toxicol Lett 209:227–31
  • Powers CM, Levin ED, Seidler FJ, Slotkin TA. 2011a. Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes. Neurotoxicol Teratol 33:329–32
  • Powers CM, Slotkin TA, Seidler FJ, Badireddy AR, Padilla S. 2011b. Silver nanoparticles alter zebrafish development and larval behavior: distinct roles for particle size, coating and composition. Neurotoxicol Teratol 33:708–14
  • Tiwari DK, Jin T, Behari J. 2011. Dose-dependent in-vivo toxicity assessment of silver nanoparticle in Wistar rats. Toxicol Mech Methods 21:13–24
  • Tolaymat TM, El Badawy AM, Genaidy A, Scheckel KG, Luxton TP, Suidan M. 2010. An evidence-based environmental perspective of manufactured silver nanoparticle in syntheses and applications: a systematic review and critical appraisal of peer-reviewed scientific papers. Sci Total Environ 408:999–1006
  • Xu L, Li X, Takemura T, Hanagata N, Wu G, Chou LL. 2012. Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel. J Nanobiotechnol 10:16–26
  • Xu L, Takemura T, Xu M, Hanagata N. 2011. Toxicity of silver nanoparticles as assessed by global gene expression analysis. Mater Express 1:74–9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.