Overestimation of nanoparticles-induced DNA damage determined by the comet assay

References

• Angelis KJ, Dusinská M, Collins AR. 1999. Single cell gel electrophoresis: detection of DNA damage at different levels of sensitivity. Electrophoresis 20:2133–8
   PubMed Web of Science ®Google Scholar
• An H, Jin B. 2012. Prospects of nanoparticle-DNA binding and its implications in medical biotechnology. Biotechnol Adv 30:1721–32
   PubMed Web of Science ®Google Scholar
• Azqueta A, Collins AR. 2013. The essential comet assay: a comprehensive guide to measuring DNA damage and repair. Arch Toxicol 87:949–68
   PubMed Web of Science ®Google Scholar
• Berkowitz DM, Kakefuda T, Sporn M. 1969. A simple and rapid method for the isolation of enzymatically active HeLa cell nuclei. J Cell Biol 42:851–4
   PubMed Web of Science ®Google Scholar
• Bitar A, Ahmad NM, Fessi H, Elaissari A. 2012. Silica-based nanoparticles for biomedical applications. Drug Discov Today 17:1147–54
   PubMed Web of Science ®Google Scholar
• Cha KE, Myung H. 2007. Cytotoxic effects of nanoparticles assessed in vitro and in vivo. J Microbiol Biotechnol 17:1573–8
   PubMed Web of Science ®Google Scholar
• Chen H, Zou Q-C, Yu H, Peng M, Song G-W, Zhang J-Z, et al. 2010. Study on interaction between cationic polystyrene nanoparticles and DNA, and the detection of DNA by resonance light scattering technology. Microchim Acta 168:331–40
   Web of Science ®Google Scholar
• Chithrani BD, Chan WCW. 2007. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett 7:1542–50
   PubMed Web of Science ®Google Scholar
• Collins AR. 2004. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol 26:249–61
   PubMed Web of Science ®Google Scholar
• Colon J, Herrera L, Smith J, Patil S, Komanski C, Kupelian P, et al. 2009. Protection from radiation-induced pneumonitis using cerium oxide nanoparticles. Nanomed Nanotechnol Biol Med 5:225–31
   PubMed Web of Science ®Google Scholar
• Davda J, Labhasetwar V. 2002. Characterization of nanoparticle uptake by endothelial cells. Int J Pharm 233:51–9
   PubMed Web of Science ®Google Scholar
• De Jong WH, Borm PJ. 2008. Drug delivery and nanoparticles: applications and hazards. Int J Nanomed 3:133–49
   PubMed Web of Science ®Google Scholar
• Duthie SJ, Collins AR. 1997. The influence of cell growth, detoxifying enzymes and DNA repair on hydrogen peroxide-mediated DNA damage (measured using the comet assay) in human cells. Free Radic Biol Med 22:717–24
   PubMed Web of Science ®Google Scholar
• Ekkapongpisit M, Giovia A, Follo C, Caputo G, Isidoro C. 2012. Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups. Int J Nanomed 7:4147–58
   PubMed Web of Science ®Google Scholar
• Gao H, Shi W, Freund LB. 2005. Mechanics of receptor-mediated endocytosis. Proc Natl Acad Sci USA 102:9469–74
   PubMed Web of Science ®Google Scholar
• Gauthier NC, Monzo P, Gonzalez T, Doye A, Oldani A, Gounon P, et al. 2007. Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin. J Cell Biol 177:343–54
   PubMed Web of Science ®Google Scholar
• Gerloff K, Albrecht C, Boots AW, Förster I, Schins RPF. 2009. Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells. Nanotoxicology 3:355–64
   Web of Science ®Google Scholar
• Golbamaki N, Rasulev B, Cassano A, Robinson RLM, Benfenati E, Leszczynski J, Cronin MTD. 2015. Genotoxicity of metal oxide nanomaterials: review of recent data and discussion of possible mechanisms. Nanoscale 7:2154–98
   PubMed Web of Science ®Google Scholar
• Goodman CM, Chari NS, Han G, Hong R, Ghosh P, Rotello VM. 2006. DNA-binding by functionalized gold nanoparticles: mechanism and structural requirements. Chem Biol Drug Des 67:297–304
   PubMed Web of Science ®Google Scholar
• Kagan VE, Bayir H, Shvedova AA. 2005. Nanomedicine and nanotoxicology: two sides of the same coin. Nanomed Nanotechnol Biol Med 1:313–16
   PubMed Web of Science ®Google Scholar
• Karlsson HL. 2010. The comet assay in nanotoxicology research. Anal Bioanal Chem 398:651–66
   PubMed Web of Science ®Google Scholar
• Karlsson HL, Di Bucchianico S, Collins AR, Dusinska M. 2015. Can the comet assay be used reliably to detect nanoparticle-induced genotoxicity? Environ Mol Mutagen 56:82–96
   PubMed Web of Science ®Google Scholar
• Karlsson HL, Nygren J, Möller L. 2004. Genotoxicity of airborne particulate matter: the role of cell–particle interaction and of substances with adduct-forming and oxidizing capacity. Mutat Res Toxicol Environ Mutagen 565:1–10
   PubMed Web of Science ®Google Scholar
• Koppen G, Angelis KJ. 1998. Repair of X-ray induced DNA damage measured by the comet assay in roots of Vicia faba. Environ Mol Mutagen 32:281–5
   PubMed Web of Science ®Google Scholar
• Korzeniowska B, Nooney R, Wencel D, Mc Donagh C. 2013. Silica nanoparticles for cell imaging and intracellular sensing. Nanotechnology 24:442002
   PubMed Web of Science ®Google Scholar
• Kwon JY, Koedrith P, Seo YR. 2014. Current investigations into the genotoxicity of zinc oxide and silica nanoparticles in mammalian models in vitro and in vivo: carcinogenic/genotoxic potential, relevant mechanisms and biomarkers, artifacts, and limitations. Int J Nanomed 9:271–86
   PubMed Web of Science ®Google Scholar
• Lin M-H, Hsu T-S, Yang P-M, Tsai M-Y, Perng T-P, Lin L-Y. 2009. Comparison of organic and inorganic germanium compounds in cellular radiosensitivity and preparation of germanium nanoparticles as a radiosensitizer. Int J Radiat Biol 85:214–26
   PubMed Web of Science ®Google Scholar
• Magdolenova Z, Lorenzo Y, Collins A, Dusinska M. 2012. Can standard genotoxicity tests be applied to nanoparticles. J Toxicol Environ Health Part A 75:800–6
   PubMed Web of Science ®Google Scholar
• Mc Shan D, Ray PC, Yu H. 2014. Molecular toxicity mechanism of nanosilver. J Food Drug Anal 22:116–27
   PubMed Web of Science ®Google Scholar
• Muramatsu M, Smetana K, Busch H. 1963. Quantitative aspects of isolation of nucleoli of the Walker carcinosarcoma and liver of the rat. Cancer Res 23:510–18
   Web of Science ®Google Scholar
• Oldani A, Cormont M, Hofman V, Chiozzi V, Oregioni O, Canonici A, et al. 2009. Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells. PLoS Pathog 5:e1000603
   PubMed Web of Science ®Google Scholar
• Ostling O, Johanson KJ. 1984. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem Biophys Res Commun 123:291–8
   PubMed Web of Science ®Google Scholar
• Petersen EJ, Henry TB, Zhao J, Mac Cuspie RI, Kirschling TL, Dobrovolskaia MA, et al. 2014. Identification and avoidance of potential artifacts and misinterpretations in nanomaterial ecotoxicity measurements. Environ Sci Technol 48:4226–46
   PubMed Web of Science ®Google Scholar
• Petersen EJ, Nelson BC. 2010. Mechanisms and measurements of nanomaterial-induced oxidative damage to DNA. Anal Bioanal Chem 398:613–50
   PubMed Web of Science ®Google Scholar
• Railsback JG, Singh A, Pearce RC, Mc Knight TE, Collazo R, Sitar Z, et al. 2012. Weakly charged cationic nanoparticles induce DNA bending and strand separation. Adv Mater Weinheim 24:4261–5
   PubMed Web of Science ®Google Scholar
• Rajapakse K, Drobne D, Kastelec D, Marinsek-Logar R. 2013. Experimental evidence of false-positive Comet test results due to TiO2 particle-assay interactions. Nanotoxicology 7:1043–51
   PubMed Web of Science ®Google Scholar
• Ricci V, Galmiche A, Doye A, Necchi V, Solcia E, Boquet P. 2000. High cell sensitivity to Helicobacter pylori VacA toxin depends on a GPI-anchored protein and is not blocked by inhibition of the clathrin-mediated pathway of endocytosis. Mol Biol Cell 11:3897–909
   PubMed Web of Science ®Google Scholar
• Salata OV. 2004. Applications of nanoparticles in biology and medicine. J Nanobiotechnol 2:3
   PubMedGoogle Scholar
• Singh NP, Mc Coy MT, Tice RR, Schneider EL. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184–91
   PubMed Web of Science ®Google Scholar
• Smijs TP. 2011. Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness. Nanotechnol Sci Appl 4:95–112
   PubMedGoogle Scholar
• Smolkova B, El Yamani N, Collins AR, Gutleb AC, Dusinska M. 2015. Nanoparticles in food. Epigenetic changes induced by nanomaterials and possible impact on health. Food Chem Toxicol Int J Publ Br Ind Biol Res Assoc 77C:64–73
   Web of Science ®Google Scholar
• Sommi P, Necchi V, Vitali A, Montagna D, De Luigi A, Salmona M, et al. 2013. PaCS is a novel cytoplasmic structure containing functional proteasome and inducible by cytokines/trophic factors. PLoS One 8:e82560
   Google Scholar
• Spulber M, Baumann P, Liu J, Palivan CG. 2015. Ceria loaded nanoreactors: a nontoxic superantioxidant system with high stability and efficacy. Nanoscale 7:1411–23
   PubMed Web of Science ®Google Scholar
• Unfried K, Albrecht C, Klotz L-O, Von Mikecz A, Grether-Beck S, Schins RPF. 2007. Cellular responses to nanoparticles: target structures and mechanisms. Nanotoxicology 1:52–71
   Web of Science ®Google Scholar
• Wason MS, Zhao J. 2013. Cerium oxide nanoparticles: potential applications for cancer and other diseases. Am J Transl Res 5:126–31
   PubMed Web of Science ®Google Scholar
• Xia T, Kovochich M, Liong M, Mädler L, Gilbert B, Shi H, et al. 2008. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano 2:2121–34
   PubMed Web of Science ®Google Scholar