What's new in nanotoxicology? Implications for public health from a brief review of the 2008 literature

References

• Arora S, Jain J, Rajwade JM, Paknikar KM. 2008. Cellular responses induced by silver nanoparticles: In vitro studies. Toxicol Lett 179(2):93–100.
   PubMed Web of Science ®Google Scholar
• Artali R, Del Pra A, Foresti E, Lesci IG, Roveri N, Sabatino P. 2008. Adsorption of human serum albumin on the chrysotile surface: A molecular dynamics and spectroscopic investigation. J Roy Soc Interface/Roy Soc 5(20):273–283.
   PubMed Web of Science ®Google Scholar
• Bardi G, Tognini P, Ciofani G, Raffa V, Costa M, Pizzorusso T. 2009. Pluronic-coated carbon nanotubes do not induce degeneration of cortical neurons in vivo and in vitro. Nanomedicine 5:96–104.
   Google Scholar
• Bussy C, Cambedouzou J, Lanone S, Leccia E, Heresanu V, Pinault M, 2008. Carbon nanotubes in macrophages: Imaging and chemical analysis by X-ray fluorescence microscopy. Nano Lett 8(9):2659–2663.
   PubMed Web of Science ®Google Scholar
• Carlson C, Hussain SM, Schrand AM, Braydich-Stolle LK, Hess KL, Jones RL, 2008. Unique cellular interaction of silver nanoparticles: Size-dependent generation of reactive oxygen species. J Phys Chem B 112(43):13608–13619.
   PubMed Web of Science ®Google Scholar
• Casey A, Herzog E, Lyng FM, Byrne HJ, Chambers G, Davoren M. 2008. Single walled carbon nanotubes induce indirect cytotoxicity by medium depletion in A549 lung cells. Toxicol Lett 179(2):78–84.
   PubMed Web of Science ®Google Scholar
• Cavarra E, Fardin P, Fineschi S, Ricciardi A, De CuntoG Sallustio F, et al. 2009. Early response of gene clusters is associated with mouse lung resistance or sensitivity to cigarette smoke. Am J Physiol Lung Cell Mol Physiol 296(3):L418–29.
   Web of Science ®Google Scholar
• Chen L, Yokel RA, Hennig B, Toborek M. 2008. Manufactured aluminum oxide nanoparticles decrease expression of tight junction proteins in brain vasculature. J Neuroimmune Pharmacol 3(4):286–295.
   PubMed Web of Science ®Google Scholar
• Chou CC, Hsiao HY, Hong QS, Chen CH, Peng YW, Chen HW, 2008. Single-walled carbon nanotubes can induce pulmonary injury in mouse model. Nano Lett 8(2):437–445.
   PubMed Web of Science ®Google Scholar
• Colognato R, Bonelli A, Ponti J, Farina M, Bergamaschi E, Sabbioni E, 2008. Comparative genotoxicity of cobalt nanoparticles and ions on human peripheral leukocytes in vitro. Mutagenesis 23(5):377–382.
   PubMed Web of Science ®Google Scholar
• de Freitas ERL, Soares PRO, Santos RdP, dos Santos RL, da Silva JR, Porfirio EP, 2008. In vitro biological activities of anionic gamma-Fe2O3 nanoparticles on human melanoma cells. J Nanosci Nanotechnol 8(5):2385–2391.
   PubMed Web of Science ®Google Scholar
• Di Pasqua AJ, Sharma KK, Shi Y-L, Toms BB, Ouellette W, Dabrowiak JC, 2008. Cytotoxicity of mesoporous silica nanomaterials. J Inorganic Biochem 102(7):1416–1423.
   PubMed Web of Science ®Google Scholar
• Donaldson K, Stone V, Seaton A, Tran L, Aitken R, Poland C. 2008. Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33(3):385; author reply 386–388.
   PubMedGoogle Scholar
• Fenoglio I, Greco G, Tomatis M, Muller J, Raymundo-Pinero E, Beguin F, 2008. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: Physicochemical aspects. Chem Res Toxicol 21(9):1690–1697.
   PubMed Web of Science ®Google Scholar
• Gheshlaghi ZN, Riazi GH, Ahmadian S, Ghafari M, Mahinpour R. 2008. Toxicity and interaction of titanium dioxide nanoparticles with microtubule protein. Acta Biochimica et Biophysica Sinica 40(9):777–782.
   PubMed Web of Science ®Google Scholar
• Guo L, Von Dem Bussche A, Buechner M, Yan A, Kane AB, Hurt RH. 2008. Adsorption of essential micronutrients by carbon nanotubes and the implications for nanotoxicity testing. Small 4(6):721–727.
   PubMed Web of Science ®Google Scholar
• Han SG, Andrews R, Gairola CG, Bhalla DK. 2008. Acute pulmonary effects of combined exposure to carbon nanotubes and ozone in mice. Inhal Toxicol 20(4):391–398.
   PubMed Web of Science ®Google Scholar
• Hanley C, Layne J, Punnoose A, Reddy KM, Coombs I, Coombs A, 2008. Preferential killing of cancer cells and activated human T cells using ZnO nanoparticles. Nanotechnology 19(29):295103–295103.
   PubMed Web of Science ®Google Scholar
• Herzog E, Byrne HJ, Casey A, Davoren M, Lenz AG, Maier KL, 2009. SWCNT suppress inflammatory mediator responses in human lung epithelium in vitro. Toxicol Appl Pharmacol 234:378–390.
   Google Scholar
• Hirano S, Kanno S, Furuyama A. 2008. Multi-walled carbon nanotubes injure the plasma membrane of macrophages. Toxicol Appl Pharmacol 232(2):244–251.
   PubMed Web of Science ®Google Scholar
• Hoet P, Boczkowski J. 2008. What's new in nanotoxicology? Brief review of the 2007 literature. Nanotoxicology 2(3):171–182.
   Web of Science ®Google Scholar
• Ichihara G, Castranova V, Tanioka A, Miyazawa K. 2008. Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33(3):381–382; author reply 382–384.
   PubMedGoogle Scholar
• Jacobsen NR, Pojana G, White P, Moller P, Cohn CA, Korsholm KS, 2008. Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells. Environ Mol Mutagen 49(6):476–487.
   PubMed Web of Science ®Google Scholar
• Journeay WS, Suri SS, Moralez JG, Fenniri H, Singh B. 2008. Rosette nanotubes show low acute pulmonary toxicity in vivo. Int J Nanomedicine 3(3):373–383.
   PubMed Web of Science ®Google Scholar
• Kang SJ, Kim BM, Lee YJ, Chung HW. 2008. Titanium dioxide nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes. Environ Molec Mutagenesis 49(5):399–405.
   PubMed Web of Science ®Google Scholar
• Karlsson HL, Cronholm P, Gustafsson J, Möller L. 2008. Copper oxide nanoparticles are highly toxic: A comparison between metal oxide nanoparticles and carbon nanotubes. Chem Res Toxicol 21(9):1726–1732.
   PubMed Web of Science ®Google Scholar
• Kemp SJ, Thorley AJ, Gorelik J, Seckl MJ, O’Hare MJ, Arcaro A, 2008. Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake. Am J Respirat Cell Molec Biol 39(5):591–597.
   PubMed Web of Science ®Google Scholar
• Kisin ER, Murray AR, Keane MJ, Shi XC, Schwegler-Berry D, Gorelik O, 2007. Single-walled carbon nanotubes: Geno- and cytotoxic effects in lung fibroblast V79 cells. J Toxicol Environ Health A 70(24):2071–2079.
   PubMed Web of Science ®Google Scholar
• Kiss B, Bíró T, Czifra G, Tóth BI, Kertész Z, Szikszai Z, 2008. Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells. Experim Dermatol 17(8):659–667.
   PubMed Web of Science ®Google Scholar
• Kwon JT, Hwang SK, Jin H, Kim DS, Minai-Tehrani A, Yoon HJ, Choi M, Yoon TJ, Han DY, Kang YW, Yoon BI, Lee JK, Cho MH. Body distribution of inhaled fluorescent magnetic nanoparticles in the mice J Occup Health 2008,50(1):1–6.
   PubMed Web of Science ®Google Scholar
• Kroll A, Pillukat MH, Hahn D, Schnekenburger J. 2008. Current in vitro methods in nanoparticle risk assessment: Limitations and challenges. Eur J Pharmaceut Biopharmaceut 72:370–377.
   Google Scholar
• Lei R, Wu C, Yang B, Ma H, Shi C, Wang Q, 2008. Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: A rapid in vivo screening method for nanotoxicity. Toxicol Appl Pharmacol 232(2):292–301.
   PubMed Web of Science ®Google Scholar
• Li J, Xue Y, Han B, Li Q, Liu L, Xiao T, 2008. Application of X-ray phase contrast imaging technique in detection of pulmonary lesions induced by multi-walled carbon nanotubes in rats. J Nanosci Nanotechnol 8(7):3357–3362.
   PubMed Web of Science ®Google Scholar
• Li S-Q, Zhu R-R, Zhu H, Xue M, Sun X-Y, Yao S-D, 2008. Nanotoxicity of TiO(2) nanoparticles to erythrocyte in vitro. Food Chem Toxicol 46(12):3626–3631.
   PubMed Web of Science ®Google Scholar
• Liu J, Hopfinger AJ. 2008. Identification of possible sources of nanotoxicity from carbon nanotubes inserted into membrane bilayers using membrane interaction quantitative structure-activity relationship analysis. Chem Res Toxicol 21(2):459–466.
   PubMed Web of Science ®Google Scholar
• Liu Z, Davis C, Cai W, He L, Chen X, Dai H. 2008. Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc Natl Acad Sci USA 105(5):1410–1415.
   PubMed Web of Science ®Google Scholar
• Monteiro-Riviere NA, Inman AO, Zhang LW. 2009. Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line. Toxicol Appl Pharmacol 234(2):222–235.
   PubMed Web of Science ®Google Scholar
• Mroz RM, Schins RPF, Li H, Jimenez LA, Drost EM, Holownia A, 2008. Nanoparticle-driven DNA damage mimics irradiation-related carcinogenesis pathways. Eur Respirat J 31(2):241–251.
   PubMed Web of Science ®Google Scholar
• Muller J, Huaux F, Moreau N, Misson P, Heilier JF, Delos M, Arras M, Fonseca A, Nagy JB, Lison D. 2005. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol Appl Pharmacol 15;207(3):221–231.
   PubMed Web of Science ®Google Scholar
• Muller J, Decordier I, Hoet PH, Lombaert N, Thomassen L, Huaux F, 2008a. Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells. Carcinogenesis 29(2):427–433.
   PubMed Web of Science ®Google Scholar
• Muller J, Huaux F, Fonseca A, Nagy JB, Moreau N, Delos M, 2008b. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: toxicological aspects. Chem Res Toxicol 21(9):1698–1705.
   PubMed Web of Science ®Google Scholar
• Murdock RC, Braydich-Stolle L, Schrand AM, Schlager JJ, Hussain SM. 2008. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicolog Sci 101(2):239–253.
   PubMed Web of Science ®Google Scholar
• Oecd Environment, Health and Safety Publications, Series on the Safety of Manufactured 2008a. Nanomaterials: Current developments/activities on the safety of manufactured nanomaterials. Issue no. 7.
   Google Scholar
• Oecd Environment, Health and Safety Publications, Series on the Safety of Manufactured 2008b. Nanomaterials: Current developments/activities on the safety of manufactured nanomaterials. Issue no. 8.
   Google Scholar
• Oesterling E, Chopra N, Gavalas V, Arzuaga X, Lim EJ, Sultana R, 2008. Alumina nanoparticles induce expression of endothelial cell adhesion molecules. Toxicol Lett 178(3):160–166.
   PubMed Web of Science ®Google Scholar
• Pacurari M, Yin XJ, Zhao J, Ding M, Leonard SS, Schwegler-Berry D, 2008. Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-κB, and Akt in normal and malignant human mesothelial cells. Environ Health Perspect 116(9):1211–1217.
   PubMed Web of Science ®Google Scholar
• Park E-J, Yi J, Chung K-H, Ryu D-Y, Choi J, Park K. 2008. Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. Toxicol Lett 180(3):222–229.
   PubMed Web of Science ®Google Scholar
• Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WA, Seaton A, 2008. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3(7):423–428.
   PubMed Web of Science ®Google Scholar
• Rogers EJ, Hsieh SF, Organti N, Schmidt D, Bello D. 2008. A high throughput in vitro analytical approach to screen for oxidative stress potential exerted by nanomaterials using a biologically relevant matrix: human blood serum. Toxicol in Vitro 22(6):1639–1647.
   PubMed Web of Science ®Google Scholar
• Rotoli BM, Bussolati O, Bianchi MG, Barilli A, Balasubramanian C, Bellucci S, 2008. Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells. Toxicol Lett 178(2):95–102.
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Kisin ER, Murray AR, Kommineni C, Castranova V, Fadeel B, . 2008a. Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes. Toxicol Appl Pharmacol 231(2):235–240.
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Kisin ER, Murray AR, Kommineni C, Castranova V, Fadeel B, 2008a. Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes. Toxicol Appl Pharmacol 231(2):235–240.
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Kisin E, Murray AR, Johnson VJ, Gorelik O, Arepalli S, Hubbs AF, Mercer RR, Keohavong P, Sussman N, Jin J, Yin J, Stone S, Chen BT, Deye G, Maynard A, Castranova V, Baron PA, Kagan VE. 2008b. Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am J Physiol Lung Cell Mol Physiol 295(4):L552–565.
   PubMed Web of Science ®Google Scholar
• Simon-Deckers A, Gouget B, Mayne-L'hermite M, Herlin-Boime N, Reynaud C, Carrière M. 2008. In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes. Toxicology 253(1–3):137–146.
   PubMed Web of Science ®Google Scholar
• Sung JH, Ji JH, Yoon JU, Kim DS, Song MY, Jeong J, 2008. Lung function changes in Sprague-Dawley rats after prolonged inhalation exposure to silver nanoparticles. Inhalat Toxicol 20(6):567–574.
   PubMed Web of Science ®Google Scholar
• Szendi K, Varga C. 2008. Lack of genotoxicity of carbon nanotubes in a pilot study. Anticancer Res 28(1A):349–352.
   PubMed Web of Science ®Google Scholar
• Takagi A, Hirose A, Nishimura T, Fukumori N, Ogata A, Ohashi N, 2008. Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33(1):105–116.
   PubMed Web of Science ®Google Scholar
• Thevenot P, Cho J, Wavhal D, Timmons RB, Tang L. 2008. Surface chemistry influences cancer killing effect of TiO2 nanoparticles. Nanomed: Nanotechnol, Biol Med 4(3):226–236.
   PubMed Web of Science ®Google Scholar
• Wan R, Mo Y, Zhang X, Chien S, Tollerud DJ, Zhang Q. 2008. Matrix metalloproteinase-2 and -9 are induced differently by metal nanoparticles in human monocytes: The role of oxidative stress and protein tyrosine kinase activation. Toxicol Appl Pharmacol 233(2):276–285.
   PubMed Web of Science ®Google Scholar
• Wang J, Chen C, Liu Y, Jiao F, Li W, Lao F, 2008. Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases. Toxicol Lett 183(1–3):72–80.
   PubMed Web of Science ®Google Scholar
• Worle-Knirsch JM, Pulskamp K, Krug HF. 2006. Oops they did it again! Carbon nanotubes hoax scientists in viability assays. Nano Lett 6(6):1261–1268.
   PubMed Web of Science ®Google Scholar
• Yang ST, Wang X, Jia G, Gu Y, Wang T, Nie H, 2008. Long-term accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice. Toxicol Lett 181(3):182–189.
   PubMed Web of Science ®Google Scholar
• Yu Y, Ren W, Ren B. 2008. Nanosize titanium dioxide cause neuronal apoptosis: A potential linkage between nanoparticle exposure and neural disorder. Neurological Res. [Epub ahead of print].
   Google Scholar
• Zhu L, Chang DW, Dai L, Hong Y. 2007. DNA damage induced by multiwalled carbon nanotubes in mouse embryonic stem cells. Nano Lett 7(12):3592–3597.
   PubMed Web of Science ®Google Scholar
• Zhu M-T, Feng W-Y, Wang Y, Wang B, Wang M, Ouyang H, 2009. Particokinetics and extrapulmonary translocation of ntratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment. Toxicolog Sci 107(2):342–351.
   PubMed Web of Science ®Google Scholar