Advanced search
Publication Cover
Acta Orthopaedica Volume 81, 2010 - Issue 6
Journal homepage
1,393
Views
73
CrossRef citations to date
0
Altmetric
Research Article

Incidence of low-grade infection in aseptic loosening of total hip arthroplasty

A prospective multicenter study using extensive routine and broad-range 16S PCR with reverse line blot diagnostics

Dirk Jan F Moojen Department of Orthopaedics, University Medical Center Utrecht, Utrecht, the NetherlandsCorrespondence[email protected]
,
Gijs van Hellemondt Department of Orthopaedics, Sint Maartensclinic, Nijmegen, the Netherlands
,
H Charles Vogely Department of Orthopaedics, University Medical Center Utrecht, Utrecht, the Netherlands
,
Bart J Burger Department of Orthopaedics, Medical Center Alkmaar, Alkmaar, the Netherlands
,
Geert H I M Walenkamp Department of Orthopaedics, Maastricht University Medical Center, Research Institute CAPHRI, Maastricht, the Netherlands
,
Niek J A Tulp Department of Orthopaedics, Isala Clinics, Zwolle, the Netherlands
,
B Wim Schreurs Department of Orthopaedics, University Medical Center Sint Radboud, Nijmegen, the Netherlands
,
Frank R A J de Meulemeester Department of Orthopaedics, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands
,
Corrie S Schot Laboratory for Infectious Diseases and Perinatal Screening, Center for Infectious Disease Control Netherlands, National Institute for Public Health and the Environment, Bilthoven, the Netherlands
,
Ingrid van de Pol Laboratory for Infectious Diseases and Perinatal Screening, Center for Infectious Disease Control Netherlands, National Institute for Public Health and the Environment, Bilthoven, the Netherlands
,
Takaaki Fujishiro Departments of Pathology, Orthopaedic Surgery and the Spine Institute, Cleveland Clinic Foundation, Cleveland, OH, USA; Department of Orthopaedics, Kobe University Hospital, Kobe, Japan
,
Leo M Schouls Laboratory for Infectious Diseases and Perinatal Screening, Center for Infectious Disease Control Netherlands, National Institute for Public Health and the Environment, Bilthoven, the Netherlands
,
Thomas W Bauer Department of Orthopaedics, Kobe University Hospital, Kobe, Japan
&
Wouter J A Dhert Department of Orthopaedics, University Medical Center Utrecht, Utrecht, the Netherlands
 show all
Pages 667-673 | Received 24 Nov 2009, Accepted 02 Jul 2010, Published online: 04 Oct 2010

  • Atkins BL, Athanasou N, Deeks JJ, Crook DW, Simpson H, Peto TE, McLardy-Smith P, Berendt AR. Prospective evaluation of criteria for microbiological diagnosis of prosthetic-joint infection at revision arthroplasty. The OSIRIS Collaborative Study Group. J Clin Microbiol 1998; 36(10):2932-9.
  • Bauer TW, Parvizi J, Kobayashi N, Krebs V. Diagnosis of periprosthetic infection. J Bone Joint Surg (Am) 2006; 88(4):869-82.
  • Chong PY, Sporer SM. Case report: Salmonella infection following total hip arthroplasty. Iowa Orthop J 2005; 25:42-3.
  • Clarke MT, Roberts CP, Lee PT, Gray J, Keene GS, Rushton N. Polymerase chain reaction can detect bacterial DNA in aseptically loose total hip arthroplasties. Clin Orthop 2004; (427):132-7.
  • Engesaeter LB, Lie SA, Espehaug B, Furnes O, Vollset SE, Havelin LI. Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0-14 years in the Norwegian Arthroplasty Register. Acta Orthop Scand 2003; 74(6):644-51.
  • Fenollar F, Roux V, Stein A, Drancourt M, Raoult D. Analysis of 525 Samples To Determine the Usefulness of PCR Amplification and Sequencing of the 16S rRNA Gene for Diagnosis of Bone and Joint Infections. J Clin Microbiol 2006; 44(3):1018-28.
  • Ince A, Rupp J, Frommelt L, Katzer A, Gille J, Lohr JF Is “aseptic” loosening of the prosthetic cup after total hip replacement due to nonculturable bacterial pathogens in patients with low-grade infection? Clin Infect Dis 2004; 39 (11): 1599-603.
  • Kobayashi N, Bauer TW, Tuohy MJ, Lieberman IH, Krebs V, Togawa D, Fujishiro T, Procop GW. The comparison of pyrosequencing molecular Gram stain, culture, and conventional Gram stain for diagnosing orthopaedic infections. J Orthop Res 2006; 24(8):1641-9.
  • Lonner JH, Desai P, Dicesare PE, Steiner G, Zuckerman JD. The reliability of analysis of intraoperative frozen sections for identifying active infection during revision hip or knee arthroplasty. J Bone Joint Surg (Am) 1996; 78(10):1553-8.
  • Malchau H, Herberts P, Eisler T, Garellick G, Soderman P. The Swedish Total Hip Replacement Register. J Bone Joint Surg (Am) (Suppl 2) 2002; 84:2-20.
  • Mariani BD, Martin DS, Levine MJ, Booth RE Jr., Tuan RS. The Coventry Award. Polymerase chain reaction detection of bacterial infection in total knee arthroplasty. Clin Orthop 1996; (331):11-22.
  • McDowell A, Patrick S. Evaluation of nonculture methods for the detection of prosthetic hip biofilms. Clin Orthop 2005; (437):74-82.
  • Mirra JM, Marder RA, Amstutz HC. The pathology of failed total joint arthroplasty. Clin Orthop 1982; (170):175-83.
  • Moojen DJ, Spijkers SN, Schot CS, Nijhof MW, Vogely HC, Fleer A, Verbout AJ, Castelein RM, Dhert WJ, Schouls LM. Identification of orthopaedic infections using broad-range polymerase chain reaction and reverse line blot hybridization. J Bone Joint Surg (Am) 2007; 89(6):1298-305.
  • Neut D, van Horn JR, van Kooten TG, van der Mei HC, Busscher HJ. Detection of biomaterial-associated infections in orthopaedic joint implants. Clin Orthop 2003; (413):261-8.
  • Pandey R, Berendt AR, Athanasou NA. Histological and microbiological findings in non-infected and infected revision arthroplasty tissues. The OSIRIS Collaborative Study Group. Oxford Skeletal Infection Research and Intervention Service. Arch Orthop Trauma Surg 2000; 120(10):570-4.
  • Spangehl MJ, Masri BA, O'Connell JX, Duncan CP. Prospective analysis of preoperative and intraoperative investigations for the diagnosis of infection at the sites of two hundred and two revision total hip arthroplasties. J Bone Joint Surg (Am) 1999; 81(5):672-83.
  • Trampuz A, Piper KE, Hanssen AD, Osmon DR, Cockerill FR, Steckelberg JM, Patel R. Sonication of explanted prosthetic components in bags for diagnosis of prosthetic joint infection is associated with risk of contamination. J Clin Microbiol 2006; 44(2):628-31.
  • Trampuz A, Piper KE, Jacobson MJ, Hanssen AD, Unni KK, Osmon DR, Mandrekar JN, Cockerill FR, Steckelberg JM, Greenleaf JF, Patel R. Sonication of removed hip and knee prostheses for diagnosis of infection. N Engl J Med 2007; 357(7):654-63.
  • Tunney MM, Patrick S, Curran MD, Ramage G, Hanna D, Nixon JR, Gorman SP, Davis RI, Anderson N. Detection of prosthetic hip infection at revision arthroplasty by immunofluorescence microscopy and PCR amplification of the bacterial 16S rRNA gene. J Clin Microbiol 1999; 37(10):3281-90.
  • Zappe B, Graf S, Ochsner PE, Zimmerli W, Sendi P. Propionibacterium spp. in prosthetic joint infections: a diagnostic challenge. Arch Orthop Trauma Surg 2008; 128(10):1039-46.
  • Zimmerli W, Trampuz A, Ochsner PE Prosthetic-joint infections. N Engl J Med 2004; 35 1(16): 1645-54.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.