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Journal of Dietary Supplements Volume 6, 2009 - Issue 4
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Research Article

Response of Carcinoma In Situ (Actinic Keratosis) to Green Tea Concentrate Plus Capsicum

D. James Morré D. James Morré is affiliated with Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.Correspondence[email protected]
, PhD,
Christoph C. Geilen Christoph C. Geilen is affiliated with Department of Dermatology and Allergy, Skin Cancer Centre Charite, University of Berlin, Berlin, Germany.
, MD,
Anna M. Welch Anna M. Welch is affiliated with Sigma Medical Group, Lafayette, IN, USA.
, MD &
Dorothy M. Morré Dorothy M. Morré is affiliated with Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA.
, PhD
Pages 385-389 | Published online: 16 Nov 2009

REFERENCES

  • Chueh P-J, Kim C, Cho N, Morré DM, Morré DJ. Molecular cloning and characterization of a tumor-associated, growth-related and time-keeping hydroquinone (NADH) oxidase (NOX) of the HeLa cell surface. Biochemistry. 2002;41:3732–3741.
  • Chueh P-J, Wu L-Y, Morré DM, Morré DJ. tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (–)-epigallocatechin-3-gallate. BioFactors. 2004;20:249–263.
  • Morré DJ, Bridge A, Wu L-Y, Morré DM. Epigallocatechin gallate inhibits preferentially the NADH oxidase and growth of transformed cells in culture. Biochem Pharmacol. 2000;60:937–946.
  • Morré DJ, Chueh P-J, Morré DM. Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture. Proc Natl Acad Sci USA. 1995;92:831–1835.
  • Morré DJ, Morré DM. Synergistic capsicum-tea mixtures with anticancer activity. Pharm Pharmacol. 2003;55:987–994.
  • Morré DM, Morré DJ. Catechin-vanilloid synergies with potential clinical applications in cancer. Rejuvenation Res. 2006;9:45–55.
  • Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FD, Provenzano MD, Measurement of protein using bicinchoninic acid. Analytical Biochem. 1985;150:70–76.
  • Yagiz K, Morré DJ, Morré DM. Transgenic mouse line overpressing the cancer-specific tNOX protein has an enhanced growth and acquired drug-response phenotype. J Nutr Biochem. 2006;17:750–759.

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