Effect of Spirulina (Arthrospira) Supplementation on the Immune Response to Tetanus Toxoid Vaccination in a Mouse Model

REFERENCES

• Akao Y, Ebihara T, Masuda H, Saeki Y, Akazawa T, Hazeki K, Hazeki O, Matsumoto M, Seya T. Enhancement of antitumor natural killer cell activation by orally administered Spirulina extract in mice. Cancer Sci. 2009;100(8):1494–1501.
   PubMed Web of Science ®Google Scholar
• Amar-Singh HSS. Neonatal tetanus in Malaysia. Med J Malay. 2009;64(1):1–2.
   PubMedGoogle Scholar
• Belay A. The potential application of Spirulina (Arthrospira) as a nutritional and therapeutic supplement in health management. J Am Nutraceut Assoc. 2002;5(2):27–28.
   Google Scholar
• Belay A. Spirulina (Arthrospira): production and quality assurance. In ME Gershwin and A Belay (Eds.), Spirulina in human nutrition and health, pp. 1–25, Boca Raton: CRC Press, 2008.
   Google Scholar
• Bellei NCJ, Carraro E, Castelo A, Granato CFH. Risk factors for poor immune response to influenza vaccination in elderly people. The Brazil J Infect Dis. 2006;10(4):269–273.
   PubMedGoogle Scholar
• Brochers AT, Belay A, Keen CL, Gershwin ME. Spirulina and immunity. In: ME Gershwin and A. Belay (Eds.), Spirulina in human nutrition and health, pp. 177–193. Boca Raton: CRC Press, 2008.
   Google Scholar
• Chu WL, Lim YW, Radhakrishnan AK, Lim PE. Protecctive effect of aqueous extract from Spirulina platensis against cell death induced by free radicals. BMC Complement Altern Med. 2010;10:53.
   PubMed Web of Science ®Google Scholar
• Deng R, Chow TJ. Hypolipidemic, antioxidant, and antiinflammatory activities of microalgae Spirulina. Cardio Therapeut. 2010;28: e33–e45
   PubMed Web of Science ®Google Scholar
• El-Sheekh MM, Mahmood YAG, Abo-Shady AM, Hamza W. Efficacy of Rhodotorula glutinis and Spirulina platensis carotenoids in immunopotentiation of mice infected with Candida albicans SC5314 and Pseudomonas aeruginosa 35. Folia Microbiol. 2010;55(1):61–67.
   PubMed Web of Science ®Google Scholar
• Grzanna R, Polotsky A, Phan PV, Pugh N, Pasco D, Frondoza CG. Immolina, a high-molecular-weight polysaccharide fraction of Spirulina, enhances chemokine expression in human monocytic THP-cells. J Altern Complement Med. 2006;12(5):429–435.
   PubMed Web of Science ®Google Scholar
• Halperin SA, Smith B, Nolan C, Shay J, Kralovec J. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. Can Med Assoc J. 2003;169(2):111–117.
   PubMed Web of Science ®Google Scholar
• Hayashi O, Hirahashi T, Katoh T, Miyajima H, Hirano T, Okuwaki Y. Class specific influence of dietary Spirulina platensis on antibody production in mice. J Nutr Sci Vitaminol. (Tokyo). 1998;44:841–851.
   PubMed Web of Science ®Google Scholar
• Hayashi O, Ishii K, Kato T. Spirulina and antibody production. In: ME Gershwin and A Belay (Eds.), Spirulina in human nutrition and health, pp. 205–226, Boca Raton: CRC Press, 2008
   Google Scholar
• Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol. (Tokyo). 1994;40:431–441.
   PubMed Web of Science ®Google Scholar
• Hwang JH, Lee IT, Jeng KC, Wang MF, Hou RCW, Wu SM, Chan YC. Spirulina prevents memory dysfunction, reduces oxidative stress damage and augments antioxidant activity in senescence-accelerated mice. J Nutr Sci Vitaminol. 2011;57:186–191.
   PubMed Web of Science ®Google Scholar
• Ishii K, Katoh T, Okuwaki Y, Hayashi O. Influence of dietary Spirulina platensis on IgA level in human saliva. J Kagawa Nutr Uni. 1999;30:27–33.
   Google Scholar
• Kilian HD, Nielsen G. Cell-mediated and humoral immune response to tetanus vaccination in onchocerciasis patients. Annal Trop Med Parasitol. 1980;40:285–291.
   Google Scholar
• Kumar N, Singh S, Patro N, Patro I. Evaluation of protective efficacy of Spirulina platensis against collagen-induced arthritis in rats. Inflammopharmacology. 2009;17(3):181–190.
   PubMedGoogle Scholar
• Lobner M, Walsted A, Larsen R, Bendtzen K, Nielsen CH. Enhancement of human adaptive immune responses by administration of a high-molecular-weight polysaccharide fraction from the cyanbacterium Arthrospira platensis. J Med Food. 2008;11(2):313–322.
   PubMed Web of Science ®Google Scholar
• Mahalingam D, Radhakrishnan AK, Amom Z, Ibrahim N, Nesaretnam K. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy individuals. Eur J Clin Nutr. 2011;65:63–69.
   PubMed Web of Science ®Google Scholar
• Mani UV, Iyer UM, Dhruv SA, Mani IU, Sharma KS. Therapeutic utility of Spirulina. In: ME Gershwin and A Belay (Eds.), Spirulina in human nutrition and health. pp. 71–99, Boca Raton: CRC Press, 2008.
   Google Scholar
• Mao TK, van de Water J, Gershwin ME. Effects of Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. J Med Food 2005;8(1):27–30.
   PubMed Web of Science ®Google Scholar
• Nemoto-Kawamura C, Hirahasi T, Nagai T, Yamada H, Katoh T, Hayashi O. Phycocyanin enhances secretory IgA antibody response and suppresses allergic IgE antibody response in mice immunized with antigen-entrapped biodegradable microparticles. J Nutr Sci Vitaminol (Tokyo). 2004;50(2):129–136.
   PubMed Web of Science ®Google Scholar
• Nesaretnam K, Mahalingam D, Radhakrishnan AK, Premier R. Supplementation of tocotrienol-rich fraction increases interferon-gamma production in ovalbumin-immunized mice. Eur J Lipid Sci Technol. 2010;112:531–536.
   Web of Science ®Google Scholar
• Nielsen CH, Balachandran P, Christensen O, Pugh ND, Tamta H, Sufka KJ, Wu X, Walsted A, Thyssen MS, Enevold C, Pasco DS. Enhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteins. Planta Medica. 2010;76(16):1802–1808.
   PubMed Web of Science ®Google Scholar
• Nookala S, Srinivasan S, Kaliraj P, Narayanan RB, Nutman TB. Impariment of tetanus-specific cellular and humoral responses following tetanus vaccination in human lymphatic filariasis. Infect Immun. 2004;72(5):2598–2604.
   PubMed Web of Science ®Google Scholar
• Qureshi MA, Garlich JD, Kidd MT. Dietary Spiurlina platensis enhances humoral and cell-mediated immune functions in chickens. Immunopharmacol Immunotoxicol. 1996;18(3): 465–476.
   PubMed Web of Science ®Google Scholar
• Remarque FJ, Cools HJ, Boere TJ, van der Klis RJ, Masurel N, Lighthart GJ. Functional disability and antibody response to influenza vaccine in elderly patients in a Dutch nursing home. Brit Med J. 1996;312:1015.
   PubMedGoogle Scholar
• Wolvers DAW, van Herpen-Broekmans WMR, Logman MHGM, van der Wielen RPJ, Albers R. Effect of a mixture of micronutrients, but not bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study. Nutr J. 2006;5:28.
   PubMed Web of Science ®Google Scholar
• Yang LL, Zhou QJ, Wang Y, Gao Y, Wang YQ. Comparison of the therapeutic effects of extracts from Spirulina platensis and amnion membrane on inflammation-associated corneal neovascularization. Int J Ophtalmol. 2012;5(1):332–337.
   Web of Science ®Google Scholar