Gene Expression Analysis of Ectopic Bone Formation Induced by Electroporatic Gene Transfer of BMP4

References

• Katagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T, Rosen V, Wozney .TM, Fuji-sawa-Sehara A, Suda T (1994) Bone morphogenetic protein-2 converts the differentiation pat-hway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 127: 1755–1766.
   Google Scholar
• Ebisawa T, Tada K, Kitajima I, Tojo K, Sampath TK, Kawabata M, Miyazono K, Imamura T (1999) Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast diffe-rentiation. J Cell Sci 112: 3519–3527.
   PubMed Web of Science ®Google Scholar
• Asahina I, Sampath TK, Nishimura I, Hauschka PV (1993) Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from new-born rat calvaria. J Cell Biol 123: 921–933.
   PubMed Web of Science ®Google Scholar
• Wakefield LM, Winokur TS, Hollands RS, Christopherson K, Levinson AD, Sporn MB: (1990) Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution. J Clin Invest 86: 1976–1984.
   PubMed Web of Science ®Google Scholar
• Wozney JM, Rosen V, Celeste AI Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA (1988) Novel regulators of bone formation: molecular clones and activities. Science 242: 1528–1534.
   PubMed Web of Science ®Google Scholar
• Musgrave DS, Bosch P, Ghivizzani S, Robbins PD, Evans CH, Huard J (1999) Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone. Bone 24: 541–547.
   PubMed Web of Science ®Google Scholar
• Kishimoto KN, Watanabe Y, Nakamura H, Kokubun S (2002) Ectopic bone formation by electroporatic transfer of bone morphogenetic protein-4 gene. Bone 31: 340–347.
   PubMedGoogle Scholar
• Reddi AH (2001) Bone morphogenetic proteins: from basic science to clinical applications. J Bone Joint Surg Am 83: 1–6.
   Google Scholar
• Stein GS, Lian JB (1993) Molecular mechanisms mediating proliferation/differentiation interre-lationships during progressive development of the osteoblast phenotype. Endocr Rev 14: 424–442.
   PubMed Web of Science ®Google Scholar
• Bianco P, Fisher LW, Young MF, Termine JD, Robey PG (1991) Expression of bone sialoprote-in (BSP) in developing human tissues. Calcif Tissue hit 49: 421–426.
   PubMed Web of Science ®Google Scholar
• Chen J, Shapiro HS, Sodek J (1992) Development expression of bone sialoprotein mRNA in rat mineralized connective tissues. J Bone Miner Res 7: 987–997.
   PubMed Web of Science ®Google Scholar
• Doege KJ, Sasaki M, Kimura T, Yamada Y (1991) Complete coding sequence and deduced pri-mary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alternatively spliced forms. J Biol Chem 266: 894–902.
   Google Scholar
• Walcz E, Deak F, Erhardt P. Coulter SN, Fulop C, Horvath P. Doege KJ, Glant TT (1994) Com-plete coding sequence, deduced primary structure, chromosomal localization, and structural ana-lysis of murine aggrecan. Genomics 22: 364–371.
   PubMed Web of Science ®Google Scholar
• Gerstenfeld LC, Cullinane DM, Barnes GL, Graves DT, Einhorn TA (2003) Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem 88: 873–884.
   PubMed Web of Science ®Google Scholar
• Clancy BM, Johnson JD, Lambert AJ, Rezvankhah S, Wong A, Resmini C, Feldman IL, Leppa-nen S, Pittman DD (2003) A gene expression profile for endochondral bone formation: oligonuc-leotide microarrays establish novel connections between known genes and BMP-2-induced bone formation in mouse quadriceps. Bone 3: 46–63.
   Google Scholar
• Kubota K, Iseki S, Kuroda S, Oida S, Iimura T, Duarte WR, Ohya K, Ishikawa I, Kasugai S (2002) Synergistic effect of fibroblast growth factor-4 in ectopic bone formation induced by bone morphogenetic protein-2. Bone 31: 465–471.
   PubMed Web of Science ®Google Scholar
• Takita H, Vehof JVV, Jansen JA, Yamamoto M, Tabata Y, Tamura M, Kuboki Y (2004) Carrier dependent cell differentiation of bone morphogenetic protein-2 induced osteogenesis and chondrogenesis during the early implantation stage in rats. J Biomed Mater Res A 71: 181–189.
   PubMedGoogle Scholar
• Jones CM, Lyons KM, Hogan BL. (1991) Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. Development 111: 531–542.
   PubMed Web of Science ®Google Scholar
• Niwa H, Yamamura K, Miyazaki J (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene Dec 108 : 193–199.
   PubMed Web of Science ®Google Scholar
• Aihara H, Miyazaki J (1988) Gene transfer into muscle by electroporation in vivo. Nat Biotech-nol 16: 867-870, 1998
   Google Scholar
• Marusic A, Katavic V. Grcevic D, Lukic IK (1999) Genetic variability of new bone induction in mice. Bone 25: 25–32.
   PubMedGoogle Scholar
• Davis HL, Demeneix BA, Quantin B, Coulombe J, Whalen RG (1993) Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle. Hum Gene Ther 4: 733–740.
   PubMed Web of Science ®Google Scholar
• Vitadello M, Schiaffino MV, Picard A, Scarpa M, Schiaffino S (1994) Gene transfer in regenera-ting muscle. Hum Gene Ther 5: 11–18.
   PubMedGoogle Scholar
• Wells DJ. (1993) Improved gene transfer by direct plasmid injection associated with regeneration in mouse skeletal muscle. FEBS Lett 332: 179–182.
   PubMed Web of Science ®Google Scholar
• Gonda K, Nakaoka T, Yoshimura K, Otawara-Hamamoto Y, Harrii K (2000) Heterotopic ossifi-cation of degenerating rat skeletal muscle induced by adenovirus-mediated transfer of bone mor-phogenetic protein-2 gene. J Bone Miner Res15: 1056–1065.
   Google Scholar
• Kong RY, Kwan KM, Lau ET, Thomas JT, Boot-Handford RP, Grant ME, Cheah KS (1993) Intron-exon structure, alternative use of promoter and expression of the mouse collagen X gene, Co110a-1. Eur J Biochem 213: 99–111.
   PubMedGoogle Scholar
• Leali D, Dell'Era P, Stabile H, Sennino B, Chambers AF, Naldini A, Sozzani S, Nico B, Ribatti D, Presta M (2003) Osteopontin (Eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis. J Immunol. 171: 1085–1093.
   Google Scholar
• Lee K, Deeds JD, Chiba S, Un-No M, Bond AT, Segre GV (1994) Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: in situ localization of its receptor and c-fos mes-senger ribonucleic acids. Endocrinology 134: 441–450.
   PubMed Web of Science ®Google Scholar
• Young MF, Ibaraki K, Kerr JM, Lyu MS, Kozak CA (1994) Murine bone sialoprotein (BSP): cDNA cloning, mRNA expression, and genetic mapping. Mamm Genome 5: 108–111.
   PubMed Web of Science ®Google Scholar
• Hirata A, Masuda S, Tamura T, Kai K, Ojima K, Fukase A, Motoyoshi K, Kamakura K, Miya-goe-Suzuki Y, Takeda S (2003) Expression profiling of cytokines and related genes in regenera-ting skeletal muscle after cardiotoxin injection: a role for osteopontin. Am J Pathol. 163: 203–215.
   Google Scholar