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Report

Report on The ALS Association's drug discovery workshop

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Pages 81-84 | Received 23 May 2012, Accepted 24 Sep 2012, Published online: 22 Oct 2012

References

  • Ganesalingam J, An J, Shaw CE, Shaw G, Lacomis D, Bowser R. Combination of neurofilament heavy chain and complement C3 as CSF biomarkers for ALS. J Neurochem. 2011;117:528–37.
  • Volkening K, Leystra-Lantz C, Strong MJ. Human low molecular weight neurofilament (NFL) mRNA interacts with a predicted p190RhoGEF homologue (RGNEF) in humans. Amyotroph Lateral Scler. 2010;11:97–103.
  • http://www.drugs.com/nda/tafamidis_120618.htmlViewed online 26 June, 2012.
  • Wang Q, Johnson JL, Agar NY, Agar JN. Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival. PLoS Biol. 2008;6:e170.
  • Swarup V, Phaneuf D, Dupré N, Petri S, Strong M, Kriz J, Julien JP. Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways. J Exp Med. 2011;208:2429–47.
  • Cudkowicz M, Bozik ME, Ingersoll EW, Miller R, Mitsumoto H, Shefner J, . The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis. Nat Med. 2011;17:1652–6.
  • Shefner J, Cedarbaum JM, Cudkowicz ME, Maragakis N, Lee J, Jones D, . Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2012, May 16.
  • van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, . EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med. 2012 Aug 26. doi: 10.1038/nm.2901. (Epub ahead of print)
  • Chaddah MR, Dickie BG, Lyall D, Marshall CJ, Sykes JB, Bruijn LI. Meeting report of the International Consortium of Stem Cell Networks’ Workshop Towards Clinical Trials Using Stem Cells for Amyotrophic Lateral Sclerosis/Motor Neuron Disease. Amyotroph Lateral Scler. 2011;12:315–7. Epub 2011, Aug 3.
  • Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, . Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proc Natl Acad Sci U S A. 2012;109:5803–8. Epub 2012, Mar 26.

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