Key immune cell cytokines have a significant role in the expansion of CD26 population of cord blood mononuclear cells

References

• Alpdogan O, Schmaltz C, Muriglan SJ, Kappel BJ, Perales MA, Rotolo JA, et al. Administration of interleukin-7 after allogeneic bone marrow transplantation improves immune reconstitution without aggravating graft-versus-host disease. Blood. 2001;98:2256–2265.
   PubMed Web of Science ®Google Scholar
• Boelens JJ, Aldenhoven M, Purtill D, Ruggeri A, Defor T, Wynn R, et al. Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning. Blood. 2013;121:3981–3987.
   PubMed Web of Science ®Google Scholar
• Bordeaux-Rego P, Luzo A, Costa FF, Olalla Saad ST, Crosara-Alberto DP. Both interleukin-3 and interleukin-6 are necessary for better ex vivo expansion of CD133 + cells from umbilical cord blood. Stem Cells Dev. 2010;19:413–422.
   PubMed Web of Science ®Google Scholar
• Campbell TB, Hangoc G, Liu Y, Pollok K, Broxmeyer HE. Inhibition of CD26 in human cord blood CD34 + cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice. Stem Cells Dev. 2007;16:347–354.
   PubMed Web of Science ®Google Scholar
• Carayol G, Robin C, Bourhis JH, Bennaceur‐Griscelli A, Chouaib S, Coulombel L, Caignard A. NK cells differentiated from bone marrow, cord blood and peripheral blood stem cells exhibit similar phenotype and functions. Eur J Immunol. 1998;28:1991–2002.
   PubMed Web of Science ®Google Scholar
• Cavazzana-Calvo M, Hacein-Bey S, de Saint Basile G, De Coene C, Selz F, Le Deist F, Fischer A. Role of interleukin-2 (IL-2), IL-7, and IL-15 in natural killer cell differentiation from cord blood hematopoietic progenitor cells and from gamma c transduced severe combined immunodeficiency X1 bone marrow cells. Blood. 1996;88:3901–3909.
   PubMed Web of Science ®Google Scholar
• Cheng M, Charoudeh HN, Brodin P, Tang Y, Lakshmikanth T, Hoglund P, et al. Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development. J Immunol. 2009;182:1460–1468.
   PubMed Web of Science ®Google Scholar
• Christopherson KW II, Hangoc G, Mantel CR, Broxmeyer HE. Modulation of hematopoietic stem cell homing and engraftment by CD26. Science. 2004;305:1000–1003.
   PubMed Web of Science ®Google Scholar
• Christopherson KW II, Paganessi LA, Napier S, Porecha NK. CD26 inhibition on CD34 + or lineage-human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice. Stem Cells Dev. 2007;16:355–360.
   PubMed Web of Science ®Google Scholar
• Christopherson KW, Cooper S, Broxmeyer HE. Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cells. Blood. 2003;101:4680–4686.
   PubMed Web of Science ®Google Scholar
• Christopherson KW, Frank RR, Jagan S, Paganessi LA, Gregory SA, Fung HC. CD26 protease inhibition improves functional response of un-fractionated cord blood, bone marrow, and mobilized peripheral blood cells to CXCL12/SDF-1. Exp Hematol. 2012;40:945–952.
   PubMed Web of Science ®Google Scholar
• Christopherson KW, Hangoc G, Broxmeyer HE. Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1α-mediated chemotaxis of human cord blood CD34 + progenitor cells. J Immunol. 2002;169:7000–7008.
   PubMed Web of Science ®Google Scholar
• Cordero OJ, Salgado FJ, Vinuela JE, Nogueira M. Interleukin-12 enhances CD26 expression and dipeptidyl peptidase IV function on human activated lymphocytes. Immunobiology. 1997;197:522–533.
   PubMed Web of Science ®Google Scholar
• Delaney C, Ratajczak MZ, Laughlin MJ. Strategies to enhance umbilical cord blood stem cell engraftment in adult patients. Expert Rev Hematol. 2010;3:273–283.
   PubMed Web of Science ®Google Scholar
• Drucker DJ. Dipeptidyl peptidase-4 inhibition and the treatment of type 2 diabetes: preclinical biology and mechanisms of action. Diabetes Care. 2007;30:1335–1343.
   PubMed Web of Science ®Google Scholar
• Eric-Nikolic A, Matic IZ, Dordevic M, Milovanovic Z, Markovic I, Dzodic R, et al. Serum DPPIV activity and CD26 expression on lymphocytes in patients with benign or malignant breast tumors. Immunobiology. 2011;216:942–946.
   PubMed Web of Science ®Google Scholar
• Fry TJ, Mackall CL. Interleukin-7: from bench to clinic. Blood. 2002;99:3892–3904.
   PubMed Web of Science ®Google Scholar
• Hofmeister C, Zhang J, Knight K, Le P, Stiff P. Ex vivo expansion of umbilical cord blood stem cells for transplantation: growing knowledge from the hematopoietic niche. Bone Marrow Transpl. 2007;39:11–23.
   PubMed Web of Science ®Google Scholar
• Kahne T, Lendeckel U, Wrenger S, Neubert K, Ansorge S, Reinhold D. Dipeptidyl peptidase IV: a cell surface peptidase involved in regulating T cell growth (review). Int J Mol Med. 1999;4:3–15.
   PubMed Web of Science ®Google Scholar
• Kita K, Lee JO, Finnerty CC, Herndon DN. Cord blood-derived hematopoietic stem/progenitor cells: current challenges in engraftment, infection, and ex vivo expansion. Stem Cells Int. 2011;2011:276193.
   PubMed Web of Science ®Google Scholar
• Le-Barillec K, Magalhaes JG, Corcuff E, Thuizat A, Sansonetti PJ, Phalipon A, Di Santo JP. Roles for T and NK cells in the innate immune response to Shigella flexneri. J Immunol. 2005;175:1735–1740.
   PubMed Web of Science ®Google Scholar
• Li Y, Schmidt-Wolf IG, Wu YF, Huang SL, Wei J, Fang J, et al. Optimized protocols for generation of cord blood-derived cytokine-induced killer/natural killer cells. Anticancer Res. 2010;30:3493–3499.
   PubMed Web of Science ®Google Scholar
• Mayani H, Dragowska W, Lansdorp PM. Cytokine-induced selective expansion and maturation of erythroid versus myeloid progenitors from purified cord blood precursor cells. Blood. 1993;81:3252–3258.
   PubMed Web of Science ®Google Scholar
• Meazza R, Azzarone B, Orengo AM, Ferrini S. Role of common-gamma chain cytokines in NK cell development and function: perspectives for immunotherapy. J Biomed Biotechnol. 2011;2011:861920.
   PubMedGoogle Scholar
• Metcalfe C, Cresswell P, Barclay AN. Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor. Open Biol. 2012;2:110036.
   PubMed Web of Science ®Google Scholar
• Notarangelo LD, Giliani S, Mella P, Schumacher RF, Mazza C, Savoldi G, et al. Combined immunodeficiencies due to defects in signal transduction: defects of the gammac-JAK3 signaling pathway as a model. Immunobiology. 2000;202:106–119.
   PubMed Web of Science ®Google Scholar
• Nozad Charoudeh H, Tang Y, Cheng M, Cilio CM, Jacobsen SE, Sitnicka E. Identification of an NK/T cell-restricted progenitor in adult bone marrow contributing to bone marrow- and thymic-dependent NK cells. Blood. 2010;116:183–192.
   PubMed Web of Science ®Google Scholar
• Oran B, Shpall E. Umbilical cord blood transplantation: a maturing technology. Hematology Am Soc Hematol Educ Program. 2012;2012:215–222.
   PubMed Web of Science ®Google Scholar
• Parrish YK, Baez I, Milford TA, Benitez A, Galloway N, Rogerio JW, et al. IL-7 Dependence in human B lymphopoiesis increases during progression of ontogeny from cord blood to bone marrow. J Immunol. 2009;182:4255–4266.
   PubMed Web of Science ®Google Scholar
• Prabhash K, Khattry N, Bakshi A, Karandikar R, Joshi A, Kannan S, et al. CD26 expression in donor stem cell harvest and its correlation with engraftment in human haematopoietic stem cell transplantation: potential predictor of early engraftment. Ann Oncol. 2010;21:582–588.
   PubMed Web of Science ®Google Scholar
• Ranson T, Vosshenrich CA, Corcuff E, Richard O, Laloux V, Lehuen A, Di Santo JP. IL-15 availability conditions homeostasis of peripheral natural killer T cells. Proc Natl Acad Sci U S A. 2003;100:2663–2668.
   PubMed Web of Science ®Google Scholar
• Ranson T, Vosshenrich CA, Corcuff E, Richard O, Muller W, Di Santo JP. IL-15 is an essential mediator of peripheral NK-cell homeostasis. Blood. 2003;101:4887–4893.
   PubMed Web of Science ®Google Scholar
• Rao M, Ahrlund‐Richter L, Kaufman DS. Concise review: cord blood banking, transplantation and induced pluripotent stem cell: success and opportunities. Stem Cells. 2012;30:55–60.
   PubMed Web of Science ®Google Scholar
• Ren Z, Jiang Y. Umbilical cord blood hematopoietic stem cell expansion ex vivo. J Blood Disorders Transf 2013;S3:2.
   Google Scholar
• Salgado FJ, Vela E, Martin M, Franco R, Nogueira M, Cordero OJ. Mechanisms of CD26/dipeptidyl peptidase IV cytokine-dependent regulation on human activated lymphocytes. Cytokine. 2000;12:1136–1141.
   PubMed Web of Science ®Google Scholar
• Sirskyj D, Theze J, Kumar A, Kryworuchko M. Disruption of the gamma c cytokine network in T cells during HIV infection. Cytokine. 2008;43:1–14.
   PubMed Web of Science ®Google Scholar
• Sitnicka E, Brakebusch C, Martensson IL, Svensson M, Agace WW, Sigvardsson M, et al. Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis. J Exp Med. 2003;198:1495–1506.
   PubMed Web of Science ®Google Scholar
• Sitnicka E, Buza-Vidas N, Ahlenius H, Cilio CM, Gekas C, Nygren JM, et al. Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors. Blood. 2007;110:2955–2964.
   PubMed Web of Science ®Google Scholar
• Ueda T, Tsuji K, Yoshino H, Ebihara Y, Yagasaki H, Hisakawa H, et al. Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor. J Clin Invest. 2000;105:1013–1021.
   PubMed Web of Science ®Google Scholar
• Vanham G, Kestens L, De Meester I, Vingerhoets J, Penne G, Vanhoof G, et al. Decreased expression of the memory marker CD26 on both CD4 + and CD8 + T lymphocytes of HIV-infected subjects. J Acquir Immune Defic Syndr. 1993;6:749–757.
   PubMed Web of Science ®Google Scholar
• Vitale M, Sivori S, Pende D, Augugliaro R, Di Donato C, Amoroso A, et al. Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones. Proc Natl Acad Sci U S A. 1996;93:1453–1457.
   PubMed Web of Science ®Google Scholar
• Vosshenrich CA, Ranson T, Samson SI, Corcuff E, Colucci F, Rosmaraki EE, Di Santo JP. Roles for common cytokine receptor gamma-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo. J Immunol. 2005;174:1213–1221.
   PubMed Web of Science ®Google Scholar
• Vosshenrich CA, Samson-Villeger SI, Di Santo JP. Distinguishing features of developing natural killer cells. Curr Opin Immunol. 2005;17:151–158.
   PubMed Web of Science ®Google Scholar
• Wagner J, Steinbuch M, Kernan N, Broxmayer H, Gluckman E. Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease. Lancet. 1995;346:214–219.
   PubMed Web of Science ®Google Scholar
• Wagner JE, Barker JN, DeFor TE, Baker KS, Blazar BR, Eide C, et al. Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival. Blood. 2002;100:1611–1618.
   PubMed Web of Science ®Google Scholar
• Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol. 2006;6:595–601.
   PubMed Web of Science ®Google Scholar
• Xu R, Reems JA. Umbilical cord blood progeny cells that retaina CD34 + phenotype after ex vivo expansion have less engraftment potential than unexpanded CD34 + cells. Transfusion. 2001;41:213–218.
   PubMed Web of Science ®Google Scholar
• Yu DM, Wang XM, McCaughan GW, Gorrell MD. Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis. FEBS J. 2006;273:2447–2460.
   PubMed Web of Science ®Google Scholar
• Zhang Q, Wang HY, Liu X, Bhutani G, Kantekure K, Wasik M. IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK. Proc Natl Acad Sci U S A. 2011;108:11977–11982.
   PubMed Web of Science ®Google Scholar