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Journal of Medical Economics Volume 14, 2011 - Issue 6
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Original Article

The cost implications of the use of telmisartan or ramipril in patients at high risk for vascular events: the ONTARGET study

Andre LamyCADENCE Research Group, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada, Department of Surgery, Department of Clinical Epidemiology and Biostatistics, and Population Health Research Institute, McMaster University Hamilton, Ontario, CanadaCorrespondence[email protected]
,
Xiaoyin WangCADENCE Research Group, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada, and Population Health Research Institute, McMaster University Hamilton, Ontario, Canada
,
Peggy GaoPopulation Health Research Institute, McMaster University Hamilton, Ontario, Canada
,
Wesley TongCADENCE Research Group, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada, and Population Health Research Institute, McMaster University Hamilton, Ontario, Canada
,
Amiram GafniDepartment of Clinical Epidemiology and Biostatistics, Population Health Research Institute, McMaster University, and Center for Health Economics and Policy Analysis, McMaster University Hamilton, Ontario, Canada
,
Antonio DansSection of Adult Medicine, College of Medicine, University of the Philippines ManilaPhilippines
,
Alvaro AvezumResearch Division, Instituto Dante Pazzanese de Cardiologia Sao Paulo, Brazil
,
Rafael FerreiraPraceta do Comercio Alfragide, Amadora, Portugal
,
James YoungKaufman Center for Heart Failure, Cleveland Clinic Cleveland, OH, USA
,
Salim YusufDepartment of Clinical Epidemiology and Biostatistics, Population Health Research Institute, and Department of Cardiology, McMaster University Hamilton, Ontario, Canada
,
Koon TeoDepartment of Clinical Epidemiology and Biostatistics, Population Health Research Institute, and Department of Cardiology, McMaster University Hamilton, Ontario, Canada
& on behalf of the ONTARGET Investigators show all
Pages 792-797 | Accepted 22 Sep 2011, Published online: 10 Oct 2011

References

  • The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, Ramipril, on cardiovascular events in high-risk patients. N Engl J Med 2000;342:145–53
  • Lamy A, Yusuf S, Pogue J, et al. Cost implications of the use of Ramipril in high-risk patients based on the Heart Outcomes Prevention Evaluation (HOPE) study. Circulation 2003;107:960–5
  • Murray JJV. ACE inhibitors in cardiovascular disease-unbeatable? N Engl J Med 2008;358:1615–6
  • The ONTARGET Investigators. Telmisartan, Ramipril, or both in patients at high risk for vascular events. N Engl J Med 2008;358:1547–59
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  • Watanabe M, Inukai K, Sumita T, et al. Effects of telmisartan on insulin resistance in Japanese type 2 diabetic patients. Inter Med 2009;49:1843–7
  • Suksomboon N, Poolsup N, Prasit T. Systemic review of the effect of telmisartan on insulin sensitivity in hypertensive patients with insulin resistance or diabetes. J Clin Pharm Ther 2011; published online 17 January 2011, doi: 10.1111/j.1365-2710.2011.01295.x

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