Increased Prevalence of Metabolic Syndrome in Individuals with Osteoarthritis: An Analysis of NHANES III Data

References

• . Chan KW, Ngai HY, Ip KK, Lam KH, Lai WW. Co-morbidities of patients with knee osteoarthritis. Hong Kong Med J. 2009;15(3):168–172
   PubMedGoogle Scholar
• . Dahaghin S, Bierma-Zeinstra SM, Koes BW, Hazes JM, Pols HA. Do metabolic factors add to the effect of overweight on hand osteoarthritis? The Rotterdam Study. Ann Rheum Dis. 2007;66(7):916–920
   PubMed Web of Science ®Google Scholar
• . Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009;9:88
   PubMed Web of Science ®Google Scholar
• . Pereira RM, de Carvalho JF, Bonfá E. Metabolic syndrome in rheumatological diseases. Autoimmun Rev. 2009;8(5):415–419
   PubMed Web of Science ®Google Scholar
• . Singh G, Miller JD, Lee FH, Pettitt D, Russell MW. Prevalence of cardiovascular disease risk factors among US adults with self-reported osteoarthritis: data from the Third National Health and Nutrition Examination Survey. Am J Manag Care. 2002;8( 15 suppl):S383–S391
   PubMed Web of Science ®Google Scholar
• . Grotle M, Hagen KB, Natvig B, Dahl FA, Kvien TK. Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up. BMC Musculoskelet Disord. 2008;9:132
   PubMed Web of Science ®Google Scholar
• . Grotle M, Hagen KB, Natvig B, Dahl FA, Kvien TK. Prevalence and burden of osteoarthritis: results from a population survey in Norway. J Rheumatol. 2008;35(4):677–684
   PubMed Web of Science ®Google Scholar
• . Engström G, Gerhardsson de Verdier M, Rollof J, Nilsson PM, Lohmander LS. C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study. Osteoarthritis Cartilage. 2009;17(2):168–173
   Google Scholar
• . Dzau VJ, Antman EM, Black HR, . The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation. 2006;114(25):2850–2870
   Web of Science ®Google Scholar
• . Bastard JP, Maachi M, Lagathu C, . Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw. 2006;17(1):4–12
   PubMed Web of Science ®Google Scholar
• . Jiamsripong P, Mookadam M, Honda T, Khandheria BK, Mookadam F. The metabolic syndrome and cardiovascular disease: Part I. Prev Cardiol. 2008;11(3):155–161
   Google Scholar
• . Abramson SB. Osteoarthritis and nitric oxide. Osteoarthritis Cartilage. 2008;16( suppl 2):S15–S20
   PubMed Web of Science ®Google Scholar
• . Hermann M. Cyclooxygenase-2 and nitric oxide. J Cardiovasc Pharmacol. 2006;47( suppl 1):S21–S25
   Google Scholar
• . Pottie P, Presle N, Terlain B, Netter P, Mainard D, Berenbaum F. Obesity and osteoarthritis: more complex than predicted! Ann Rheum Dis. 2006;65(11):1403–1405
   PubMed Web of Science ®Google Scholar
• . Rojas-Rodriguez J, Escobar-Linares LE, Garcia-Carrasco M, . The relationship between the metabolic syndrome and energy-utilization deficit in the pathogenesis of obesity-induced osteoarthritis. Med Hypotheses. 2007;69(4):860–868
   Google Scholar
• . Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;285(19):2486–2497
   PubMed Web of Science ®Google Scholar
• . Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey Data, Survey Questionnaire, Examination and Laboratory Protocols. Hyattsville, MD: Center for Disease Control and Prevention. National Center for Health Statistics (NCHS), US Dept of Health and Human Services; 2002
   Google Scholar
• . Mohadjer L, Montaquila J, Waksberg J, . National Health and Nutrition Examination Survey III: Weighting and Estimation Methodology. Rockville, MD: Westat, Inc.
   Google Scholar
• . Elkader A, Sproule B. Buprenorphine: clinical pharmacokinetics in the treatment of opioid dependence. Clin Pharmacokinet. 2005;44(7):661–680
   PubMed Web of Science ®Google Scholar
• . Hart DJ, Doyle DV, Spector TD. Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study. Arthritis Rheum. 1999;42(1):17–24
   Google Scholar
• . Sharma L, Kapoor D, Issa S. Epidemiology of osteoarthritis: an update. Curr Opin Rheumatol. 2006;18(2):147–156
   PubMed Web of Science ®Google Scholar
• . Urwin M, Symmons D, Allison T, . Estimating the burden of musculoskeletal disorders in the community: the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation. Ann Rheum Dis. 1998;57(11):649–655
   PubMed Web of Science ®Google Scholar
• . Pearson TA, Blair SN, Daniels SR, . AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American Heart Association Science Advisory and Coordinating Committee. Circulation. 2002;106(3):388–391
   PubMed Web of Science ®Google Scholar
• . Erhardt LR. Rationale for multiple risk intervention: the need to move from theory to practice. Vasc Health Risk Manag. 2007;3(6):985–997
   PubMedGoogle Scholar
• . Grundy SM. Metabolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab. 2007;92(2):399–404
   PubMed Web of Science ®Google Scholar
• . Hadi HA, Suwaidi JA. Endothelial dysfunction in diabetes mellitus. Vasc Health Risk Manag. 2007;3(6):853–876
   PubMedGoogle Scholar
• . Yanai H, Tomono Y, Ito K, Furutani N, Yoshida H, Tada N. The underlying mechanisms for development of hypertension in the metabolic syndrome. Nutr J. 2008;7:10
   PubMed Web of Science ®Google Scholar
• . Motsko SP, Rascati KL, Busti AJ, . Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk. Drug Saf. 2006;29(7):621–632
   PubMed Web of Science ®Google Scholar
• . Antman EM, Bennett JS, Daugherty A, Furberg C, Roberts H, Taubert KA. Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association. Circulation. 2007;115(12):1634–1642
   PubMed Web of Science ®Google Scholar
• . Tannenbaum H, Bombardier C, Davis P, Russell AS; Third Canadian Consensus Conference Group. An evidence-based approach to prescribing nonsteroidal antiinflammatory drugs. Third Canadian Consensus Conference. J Rheumatol. 2006;33(1):140–157
   Google Scholar
• . Chan AT, Manson JE, Albert CM, . Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events. Circulation. 2006;113(12):1578–1587
   PubMed Web of Science ®Google Scholar
• . Zhang W, Moskowitz RW, Nuki G, . OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence. Osteoarthritis Cartilage. 2007;15(9):981–1000
   PubMed Web of Science ®Google Scholar
• . Cashman JN. The mechanisms of action of NSAIDs in analgesia. Drugs. 1996;52( suppl 5):13–23
   PubMed Web of Science ®Google Scholar
• . Urban MK. COX-2 specific inhibitors offer improved advantages over traditional NSAIDs. Orthopedics. 2000;23( suppl 7):S761–S764
   PubMed Web of Science ®Google Scholar
• . Doutremepuich C, Aguejouf O, Eizayaga FX, Desplat V. Reverse effect of aspirin: is the prothrombotic effect after aspirin discontinuation mediated by cyclooxygenase 2 inhibition? Pathophysiol Haemost Thromb. 2007;36(1):40–44
   Google Scholar
• . Funk CD, FitzGerald GA. COX-2 inhibitors and cardiovascular risk. J Cardiovasc Pharmacol. 2007;50(5):470–479
   PubMed Web of Science ®Google Scholar
• . Krotz F, Schiele TM, Klauss V, Sohn HY. Selective COX-2 inhibitors and risk of myocardial infarction. J Vasc Res. 2005;42(4):312–324
   Google Scholar
• . Martinez-Gonzalez J, Badimon L. Mechanisms underlying the cardiovascular effects of COX-inhibition: benefits and risks. Curr Pharm Des. 2007;13(22):2215–2227
   PubMed Web of Science ®Google Scholar
• . Riess W, Schmid K, Botta L, . Die perkutane Resorption von Diclofenac. Arzneimittelforschung. 1986;36(7):1092–1096
   PubMed Web of Science ®Google Scholar
• . Rolf C, Engstrom B, Beauchard C, Jacobs LD, Le Liboux A. Intra articular absorption and distribution of ketoprofen after topical plaster application and oral intake in 100 patients undergoing knee arthroscopy. Rheumatology (Oxford). 1999;38(6):564–567
   PubMed Web of Science ®Google Scholar
• . Kienzler JL GM, Nolleveaux F. Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers. In press. J Clin Pharmacol New Drugs.
   Google Scholar
• . Chou R, Hlefland M, Peterson K, Dana T, Roberts C. Comparative effectiveness and safety of analgesics for osteoarthritis. Comparative effectiveness review no. 4. Prepared by the Oregon Evidence-based Practice Center under Contract No. 290-02-0024. Rockville, MD: Agency for Healthcare Research and Quality; 2006. 06-EHC009-EF
   Google Scholar
• . Mason L, Moore RA, Edwards JE, Derry S, McQuay HJ. Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis. BMC Musculoskelet Disord. 2004;5:28
   PubMed Web of Science ®Google Scholar
• . Zacher J, Altman R, Bellamy N, . Topical diclofenac and its role in pain and inflammation: an evidence-based review. Curr Med Res Opin. 2008;24(4):925–950
   PubMed Web of Science ®Google Scholar
• . Tugwell PS, Wells GA, Shainhouse JZ. Equivalence study of a topical diclofenac solution (pennsaid) compared with oral diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial. J Rheumatol. 2004;31(10):2002–2012
   PubMed Web of Science ®Google Scholar
• . National Institute for Health and Clinical Excellence. Osteoarthritis: the care and management of osteoarthritis in adults. National Collaborating Centre for Chronic Conditions. February, 2008. www.nice.org.uk/CG059
   Google Scholar
• . Zhang W, Doherty M, Leeb BF, . EULAR evidence based recommendations for the management of hand osteoarthritis: report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis. 2007;66(3):377–388
   PubMed Web of Science ®Google Scholar
• . Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Arthritis Rheum. 2000;43(9):1905–1915
   PubMed Web of Science ®Google Scholar
• . Schnitzer TJ; American College of Rheumatology. Update of ACR guidelines for osteoarthritis: role of the coxibs. J Pain Symptom Manage. 2002;23( 4 suppl):S24–S31
   PubMed Web of Science ®Google Scholar
• . Altman RD, Dreiser RL, Fisher CL, Chase WF, Dreher DS, Zacher J. Diclofenac sodium gel in patients with primary hand osteoarthritis: a randomized, double-blind, placebo-controlled trial. J Rheumatol. 2009;36(9):1991–1999
   PubMed Web of Science ®Google Scholar
• . Barthel HR, Haselwood D, Longley S, Gold MS, Altman RD. Randomized controlled trial of diclofenac sodium gel in knee osteoarthritis. Semin Arthritis Rheum. In press
   Google Scholar
• . Simon LS, Grierson LM, Naseer Z, Bookman AA, Zev Shainhouse J. Efficacy and safety of topical diclofenac containing dimethyl sulfoxide (DMSO) compared with those of topical placebo, DMSO vehicle and oral diclofenac for knee osteoarthritis. Pain. 2009;143(3):238–245
   PubMed Web of Science ®Google Scholar
• . Zhang W, Doherty M, Leeb BF, . EULAR evidence based recommendations for the management of hand osteoarthritis: report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis. 2007;66(3):377–388
   PubMed Web of Science ®Google Scholar
• . Matthews P, Derry S, Moore RA, McQuay HJ. Topical rubefacients for acute and chronic pain in adults. Cochrane Database Syst Rev. 2009(3):CD007403
   Google Scholar
• . Altman R, Barkin RL. Topical therapy for osteoarthritis: clinical and pharmacologic perspectives. Postgrad Med. 2009;121(2):139–147
   PubMed Web of Science ®Google Scholar
• . Reuben SS, Connelly NR, Maciolek H. Postoperative analgesia with controlled-release oxycodone for outpatient anterior cruciate ligament surgery. Anesth Analg. 1999;88(6):1286–1291
   Google Scholar
• . American Pain Society. Guideline for the Management of Pain in Osteoarthritis, Rheumatoid Arthritis and Juvenile Chronic Arthritis. Chicago, IL: American Pain Society; 2002
   Google Scholar
• . Bhamb B, Brown D, Hariharan J, Anderson J, Balousek S, Fleming MF. Survey of select practice behaviors by primary care physicians on the use of opioids for chronic pain. Curr Med Res Opin. 2006;22(9):1859–1865
   PubMed Web of Science ®Google Scholar
• . Upshur CC, Luckmann RS, Savageau JA. Primary care provider concerns about management of chronic pain in community clinic populations. J Gen Intern Med. 2006;21(6):652–655
   PubMed Web of Science ®Google Scholar
• . Heit HA. The truth about pain management: the difference between a pain patient and an addicted patient. Eur J Pain. 2001;5( suppl A):27–29
   PubMedGoogle Scholar
• . Weaver M, Schnoll S. Abuse liability in opioid therapy for pain treatment in patients with an addiction history. Clin J Pain. 2002;18( suppl 4):S61–S69
   PubMed Web of Science ®Google Scholar
• . The use of opioids for the treatment of chronic pain. A consensus statement from the American Academy of Pain Medicine and the American Pain Society. Clin J Pain. 1997;13(1):6–8
   PubMed Web of Science ®Google Scholar
• . McIlwain H, Ahdieh H. Safety, tolerability, and effectiveness of oxymorphone extended release for moderate to severe osteoarthritis pain: a one-year study. Am J Ther. 2005;12(2):106–112
   PubMedGoogle Scholar
• . Roth SH, Fleischmann RM, Burch FX, . Around-the-clock, controlled-release oxycodone therapy for osteoarthritis-related pain: placebo-controlled trial and long-term evaluation. Arch Intern Med. 2000;160(6):853–860
   PubMedGoogle Scholar
• . Caldwell JR, Rapoport RJ, Davis JC, . Efficacy and safety of a once-daily morphine formulation in chronic, moderate-to-severe osteoarthritis pain: results from a randomized, placebo-controlled, double-blind trial and an open-label extension trial. J Pain Symptom Manage. 2002;23(4):278–291
   PubMed Web of Science ®Google Scholar
• . Gross GJ, Peart JN. Opioids and myocardial reperfusion injury. Arch Mal Coeur Vaiss. 2007;100(3):231–237
   Google Scholar
• . Schultz JE, Gross GJ. Opioids and cardioprotection. Pharmacol Ther. 2001;89(2):123–137
   Google Scholar
• . Kato R, Foex P. Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists. Can J Anaesth. 2002;49(8):777–791
   PubMed Web of Science ®Google Scholar
• . Pepe S, van den Brink OW, Lakatta EG, Xiao RP. Cross-talk of opioid peptide receptor and beta-adrenergic receptor signalling in the heart. Cardiovasc Res. 2004;63(3):414–422
   Google Scholar
• . Messier SP, Loeser RF, Mitchell MN, . Exercise and weight loss in obese older adults with knee osteoarthritis: a preliminary study. J Am Geriatr Soc. 2000;48(9):1062–1072
   PubMed Web of Science ®Google Scholar
• . Messier SP, Loeser RF, Miller GD, . Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial. Arthritis Rheum. 2004;50(5):1501–1510
   PubMed Web of Science ®Google Scholar
• . Lerman RH, Minich DM, Darland G, . Enhancement of a modified Mediterranean-style, low glycemic load diet with specific phytochemicals improves cardiometabolic risk factors in subjects with metabolic syndrome and hypercholesterolemia in a randomized trial. Nutr Metab (Lond). 2008;5:29
   PubMedGoogle Scholar
• . Solomon TP, Sistrun SN, Krishnan RK, . Exercise and diet enhance fat oxidation and reduce insulin resistance in older obese adults. J Appl Physiol. 2008;104(5):1313–1319
   Google Scholar