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Clinical Focus: ADHD, Depression, Pain, and Neurological Disorders

Opioid Titration and Conversion in Patients Receiving Morphine Sulfate and Naltrexone Hydrochloride Extended Release Capsules

, MD, , MD, , PhD, , MS & , PhD
Pages 155-164 | Published online: 13 Mar 2015

References

  • . Chou R, Fanciullo GJ, Fine PG, ; American Pain Society—American Academy of Pain Medicine Opioids Guidelines Panel. Opioid treatment guidelines. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain. 2009; 10(2):113–130
  • . Mercadante S, Bruera E. Opioid switching: A systematic and critical review. Cancer Treat Rev. 2006; 32(4):304–315
  • . Quang-Cantagrel N, Wallace M, Magnuson S. Opioid substitution to improve effectiveness of chronic non-cancer pain control: A chart review. Anesth Analg. 2000; 90(4):933–937
  • . Chou R, Ballantyne JC, Fanciullo GJ, Fine PG, Miaskovski C. Research gaps on use of opioids for chronic noncancer pain: Findings from a review of the evidence for an American Pain Society and American Academy of Pain Medicine Clinical Practice Guideline. J Pain. 2009; 10(2): 147–159
  • . Freye E, Anderson-Hillemacher A, Ritzdorf I, Levy JV. Opioid rotation from high-dose morphine to transdermal buprenorphine (Transtec) in chronic pain patients. Pain Pract. 2007; 7(2):123–129
  • . Fine PG. Clinical approaches to special issues related to opioid therapy. Sem Oncol Nurs. 2009; 25(2 suppl 1):S20–S28
  • . Pasternak G W. Molecular biology of opioid analgesia. J Pain Symptom Manage. 2005; 29( 5 suppl):S2–S9
  • . Cherny N, Ripamonti C, Pereira J, ; Expert Working Group of the European Association of Palliative Care Network. Strategies to manage the adverse effects of oral morphine: An evidence-based report. J Clin Oncol. 2001; 19(9):2542–2554
  • . Knotkova H, Fine PG, Portenoy RK. Opioid rotation: The science and the limitations of the equianalgesic dose table. J Pain Symptom Manage. 2009; 38(3):426–439
  • . Fine PG, Portenoy RK; Ad Hoc Expert Panel on Evidence Review and Guidelines for Opioid Rotation. Establishing “best practices” for opioid rotation: Conclusions of an expert panel. J Pain Symptom Manage. 2009; 38(3):418–425
  • . Embeda [package insert]. Bristol, TN: King Pharmaceuticals®, Inc.; June 2009
  • . Webster LR, Brewer R, Wang C, . Long-term safety and efficacy of morphine sulfate and naltrexone hydrochloride extended release capsules, a novel formulation containing morphine and sequestered naltrexone, in patients with chronic, moderate to severe pain. J Pain Symptom Manage. 2010; 40(5):734–746
  • . Johnson FK, Stark JG, Bieberdorf FA, Stauffer J. Relative oral bioavailability of morphine and naltrexone derived from crushed morphine sulfate and naltrexone hydrochloride extended-release capsules versus intact product and versus naltrexone solution: A single-dose, randomized-sequence, open-label, three-way crossover trial in healthy volunteers. Clin Ther. 2010; 32(6):1149–1164
  • . Stauffer J, Setnik B, Sokolowska M, Romach M, Johnson F, Sellers E. Subjective effects and safety of whole and tampered morphine sulfate and naltrexone hydrochloride (ALO-01) extended-release capsules versus morphine solution and placebo in experienced non-dependent opioid users: A randomized, double-blind, placebo-controlled, crossover study. Clin Drug Investig. 2009; 29(12):777–790
  • . Gordon DB, Stevenson KK, Griffie J, Muchka S, Rapp C, Ford-Roberts K. Opioid equianalgesic calculations. J Palliat Med. 1999; 2(2):209–218
  • . Schneider JP, Kirsh KL. Defining clinical issues around tolerance, hyperalgesia, and addiction: A quantitative and qualitative outcome study of long-term opioid dosing in a chronic pain practice. J Opioid Manage. 2010; 6(6):385–395
  • . Wesson DR, Ling W. The Clinical Opiate Withdrawal Scale (COWS). J Psychoactive Drugs. 2003; 35(2):253–259
  • . Olsen Y, Daumit GL, Ford DE. Opioid prescriptions by U.S. primary care physicians from 1992 to 2001. J Pain. 2006; 7(4):225–235
  • . Kuehn BM. Opioid prescriptions soar: Increase in legitimate use as well as abuse. JAMA. 2007; 297(3):249–251
  • . Farrar JT, Young JP Jr, LaMoreaux L, Werth JL, Poole RM. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001; 94(2):149–158
  • . Ruan X, Chen T, Gudin J, Couch JP, Chiravuri S. Acute opioid withdrawal precipitated by ingestion of crushed Embeda (morphine extended release with sequestered naltrexone): Case report and the focused review of the literature. J Opioid Manage. 2010; 6(4):300–303
  • . Jang DH, Robe JC, Hoffman RS. Severe opioid withdrawal due to misuse of new combined morphine and naltrexone product (Embeda). Ann Emerg Med. 2010; 55(3):303–304
  • . Peniston JH, Xiang Q, Gould EM. Factors affecting acceptability of titrated oxymorphone extended release in chronic low back pain-an individual patient analysis. Curr Med Res Opin. 2010; 26(8):1861–1871
  • . Hale ME, Ahdieh H, Ma T, Rauck R; Oxymorphone ER Study Group 1. efficacy and safety of OPANA ER (oxymorphone extended release) for relief of moderate to severe chronic low back pain in opioid-experienced patients: A 12-week, randomized, double-blind, placebo-controlled study. J Pain. 2007; 8(2):175–184
  • . Katz N, Rauck R, Ahdieh H, . A 12-week, randomized, placebo-controlled trial assessing the safety and efficacy of oxymorphone extended release for opioid-naive patients with chronic low back pain. Curr Med Res Opin. 2007; 23(1):117–128

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