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Clinical Features

Examining the Role of Activity, Exercise, and Pharmacology in Mild COPD

, MD, FRCPI, FRCPC & , MD

References

  • . Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management and Prevention of COPD. January 2014. http://www.goldcopd.org/. Accessed February 17, 2014
  • . Mannino DM, Gagnon RC, Petty TL, Lydick E. Obstructive lung disease and low lung function in adults in the United States: data from the National Health and Nutrition Examination Survey, 1988–1994. Arch Intern Med. 2000;160(11):1683–1689
  • . National Heart Lung and Blood Institute. Morbidity and Mortality: 2009 Chart Book on Cardiovascular, Lung, and Blood Diseases. October 2009. http://www.nhlbi.nih.gov/resources/docs/2009_ChartBook.pdf. Accessed February 17, 2014
  • . Miravitlles M, Murio C, Guerrero T, Gisbert R. Costs of chronic bronchitis and COPD: a 1-year follow-up study. Chest. 2003;123(3):784–791
  • . Cooper CB. The connection between chronic obstructive pulmonary disease symptoms and hyperinflation and its impact on exercise and function. Am J Med. 2006;119(10 Suppl 1):21–31
  • . Belfer MH, Reardon JZ. Improving exercise tolerance and quality of life in patients with chronic obstructive pulmonary disease. J Am Osteopath AsSoc. 2009;109(5):268–278
  • . Ofir D, Laveneziana P, Webb KA, Lam YM, O'Donnell DE. Mechanisms of dyspnea during cycle exercise in symptomatic patients with GOLD stage I chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008;177(6):622–629
  • . ZuWallack R. How are you doing? What are you doing? Differing perspectives in the assessment of individuals with COPD. COPD. 2007;4(3):293–297
  • . Decramer M, Rennard S, Troosters T, . COPD as a lung disease with systemic consequences-clinical impact, mechanisms, and potential for early intervention. COPD. 2008;5(4):235–256
  • . Garcia-Aymerich J, Lange P, Benet M, Schnohr P, Antó JM. Regular physical activity modifies smoking-related lung function decline and reduces risk of chronic obstructive pulmonary disease: a population-based cohort study. Am J Respir Crit Care Med. 2007;175(5):458–463
  • . Garcia-Aymerich J, Lange P, Benet M, Schnohr P, Antó JM. Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population based cohort study. Thorax. 2006;61(9):772–778
  • . Díaz AA, Morales A, Díaz JC, . CT and physiologic determinants of dyspnea and exercise capacity during the six-minute walk test in mild COPD. Respir Med. 2013;107(4):570–579
  • . Miravitlles M, Soriano JB, García-Río F, . Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities. Thorax. 2009;64(10):863–868
  • . Coronell C, Orozco-Levi M, Méndez R, Ramirez-Sarmiento A, Gáldiz JB, Gea J. Relevance of assessing quadriceps endurance in patients with COPD. Eur Respir J. 2004;24(1):129–136
  • . Troosters T, Sciurba F, Battaglia S, . Physical inactivity in patients with COPD, a controlled multi-center pilot-study. Respir Med. 2010;104(7):1005–1011
  • . O'Donnell DE, Maltais F, Porszasz J, . The continuum of physiological impairment during treadmill walking in patients with mild-to-moderate COPD: patient characterization phase of a randomized clinical trial. Plos One. 2014;9(5):e96574
  • . Mapel DW, Dalal AA, Blanchette CM, Petersen H, Ferguson GT. Severity of COPD at initial spirometry-confirmed diagnosis: data from medical charts and administrative claims. Int J Chron Obstruct Pulmon Dis. 2011;6:573–581
  • . Radin A, Cote C. Primary care of the patient with chronic obstructive pulmonary disease-part 1: frontline prevention and early diagnosis. Am J Med. 2008;121( 7 Suppl):S3–S12
  • . Tinkelman DG, Price D, Nordyke RJ, Halbert RJ. COPD screening efforts in primary care: what is the yield? Prim Care Respir J. 2007;16(1):41–48
  • . Qaseem A, Wilt TJ, Weinberger SE, . Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med. 2011;155(3):179–191
  • . O'Donnell DE, Aaron S, Bourbeau J, . Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease—2007 update. Can Respir J. 2007;14( Suppl B):5B–32B
  • . Bellamy D, Smith J. Role of primary care in early diagnosis and effective management of COPD. Int J Clin Pract. 2007;61(8):1380–1389
  • . Pitta F, Troosters T, Spruit MA, Probst VS, Decramer M, Gosselink R. Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2005;171(9):972–977
  • . Pepin V, Saey D, Laviolette L, Maltais F. Exercise capacity in chronic obstructive pulmonary disease: mechanisms of limitation. COPD. 2007;4(3):195–204
  • . Nici L, Donner C, Wouters E, . American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation. Am J Respir Crit Care Med. 2006;173(12):1390–1413
  • . McDonough JE, Yuan R, Suzuki M, . Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med. 2011;365(17):1567–1575
  • . Rodríguez-Roisin R, Drakulovic M, Rodríguez DA, Roca J, Barberà JA, Wagner PD. Ventilation-perfusion imbalance and chronic obstructive pulmonary disease staging severity. J Appl Physiol. 2009;106(6):1902–1908
  • . Thomas M, Decramer M, O'Donnell DE. No room to breathe: the importance of lung hyperinflation in COPD. Prim Care Respir J. 2013;22(1):101–111
  • . O'Donnell DE, Laveneziana P. Dyspnea and activity limitation in COPD: mechanical factors. COPD. 2007;4(3):225–236
  • . O'Donnell DE. Impacting patient-centred outcomes in COPD: breathlessness and exercise tolerance. Eur Respir Rev. 2006;15(99):37–41
  • . Cooper CB. Airflow obstruction and exercise. Respir Med. 2009; 103(3):325–334
  • . DeLorey DS, Babb TG. Progressive mechanical ventilatory constraints with aging. Am J Respir Crit Care Med. 1999;160(1):169–177
  • . O'Donnell DE, Guenette JA, Maltais F, Webb KA. Decline of resting inspiratory capacity in COPD: the impact on breathing pattern, dyspnea, and ventilatory capacity during exercise. Chest. 2012;141(3):753–762
  • . O'Donnell DE, Webb KA. The major limitation to exercise performance in COPD is dynamic hyperinflation. J Appl Physiol. 2008;105(2):753–755; discussion 755–757
  • . O'Donnell DE, Hamilton AL, Webb KA. Sensory-mechanical relationships during high-intensity, constant-work-rate exercise in COPD. J Appl Physiol. 2006;101(4):1025–1035
  • . O'Donnell DE. Hyperinflation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2006;3(2):180–184
  • . Garcia-Rio F, Lores V, Mediano O, . Daily physical activity in patients with chronic obstructive pulmonary disease is mainly associated with dynamic hyperinflation. Am J Respir Crit Care Med. 2009;180(6):506–512
  • . Williams M, Cafarella P, Olds T, Petkov J, Frith P. The language of breathlessness differentiates between patients with COPD and agematched adults. Chest. 2008;134(3):489–496
  • . Maltais F. Exercise and COPD: therapeutic responses, disease-related outcomes, and activity-promotion strategies. Phys SportsMed. 2013;41(1):66–80
  • . Oga T, Nishimura K, Tsukino M, Sato S, Hajiro T, Mishima M. Exercise capacity deterioration in patients with COPD: longitudinal evaluation over 5 years. Chest. 2005;128(1):62–69
  • . Babb TG, Viggiano R, Hurley B, Staats B, Rodarte JR. Effect of mild-to-moderate airflow limitation on exercise capacity. J Appl Physiol. 1991;70(1):223–230
  • . Carter R, Nicotra B, Blevins W, Holiday D. Altered exercise gas exchange and cardiac function in patients with mild chronic obstructive pulmonary disease. Chest. 1993;103(3):745–750
  • . Van Remoortel H, Hornikx M, Demeyer H, . Daily physical activity in subjects with newly diagnosed COPD. Thorax. 2013;68(10):962–963
  • . Castro AA, Kümpel C, Rangueri RC, . Daily activities are sufficient to induce dynamic pulmonary hyperinflation and dyspnea in chronic obstructive pulmonary disease patients. Clinics (Sao Paulo). 2012;67(4):319–325
  • . Katz PP, Gregorich S, Eisner M, . Disability in valued life activities among individuals with COPD and other respiratory conditions. J Cardiopulm Rehabil PRev. 2010;30(2):126–136
  • . Katz PP, Eisner MD, Yelin EH, . Functioning and psychological status among individuals with COPD. Qual Life Res. 2005;14(8):1835–1843
  • . Rochester CL. Exercise training in chronic obstructive pulmonary disease. J Rehabil Res Dev. 2003;40(5 Suppl 2):59–80
  • . American Thoracic Society/American College of Chest Physicians. ATS/ ACCP Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med. 2003;167(2):211–277
  • . Berry MJ, Adair NE, Rejeski WJ. Use of peak oxygen consumption in predicting physical function and quality of life in COPD patients. Chest. 2006;129(6):1516–1522
  • . Morgan MD, Singh SJ. Assessing the exercise response to a bronchodilator in COPD: time to get off your bike? Thorax. 2007;62(4):281–283
  • . Wise RA, Brown CD. Minimal clinically important differences in the six-minute walk test and the incremental shuttle walking test. COPD. 2005;2(1):125–129
  • . Solway S, Brooks D, Lacasse Y, Thomas S. A qualitative systematic overview of the measurement properties of functional walk tests used in the cardiorespiratory domain. Chest. 2001;119(1):256–270
  • . Bestall JC, Paul EA, Garrod R, Garnham R, Jones PW, Wedzicha JA. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999;54(7):581–586
  • . Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N. Development and first validation of the COPD Assessment Test. Eur Respir J. 2009;34(3):648–654
  • . Dodd JW, Hogg L, Nolan J, . The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study. Thorax. 2011;66(5):425–429
  • . Pitta F, Troosters T, Probst VS, Spruit MA, Decramer M, Gosselink R. Quantifying physical activity in daily life with questionnaires and motion sensors in COPD. Eur Respir J. 2006;27(5):1040–1055
  • . Watz H, Waschki B, Meyer T, Magnussen H. Physical activity in patients with COPD. Eur Respir J. 2009;33(2):262–272
  • . Pereira MA, FitzerGerald SJ, Gregg EW, . A collection of physical activity questionnaires for health-related research. Med Sci Sports Exerc. 1997;29( 6 Suppl):S1–S205
  • . Ward DS, Evenson KR, Vaughn A, Rodgers AB, Troiano RP. Accelerometer use in physical activity: best practices and research recommendations. Med Sci Sports Exerc. 2005;37( 11 Suppl): S582–S588
  • . Le Masurier GC, Tudor-Locke C. Comparison of pedometer and accelerometer accuracy under controlled conditions. Med Sci Sports Exerc. 2003;35(5):867–871
  • . Patel SA, Benzo RP, Slivka WA, Sciurba FC. Activity monitoring and energy expenditure in COPD patients: a validation study. COPD. 2007;4(2):107–112
  • . Waschki B, Kirsten A, Holz O, . Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study. Chest. 2011;140(2):331–342
  • . Casanova C, Cote C, Marin JM, . Distance and oxygen desaturation during the 6-min walk test as predictors of long-term mortality in patients with COPD. Chest. 2008;134(4):746–752
  • . American Thoracic Society Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166(1):111–117
  • . Turner SE, Eastwood PR, Cecins NM, Hillman DR, Jenkins SC. Physiologic responses to incremental and self-paced exercise in COPD: a comparison of three tests. Chest. 2004;126(3):766–773
  • . Revill SM, Morgan MD, Singh SJ, Williams J, Hardman AE. The endurance shuttle walk: a new field test for the assessment of endurance capacity in chronic obstructive pulmonary disease. Thorax. 1999;54(3):213–222
  • . Borel B, Provencher S, Saey D, Maltais F. Responsiveness of various exercise-testing protocols to therapeutic interventions in COPD. Pulm Med. 2013;2013:410748
  • . Lacasse Y, Martin S, Lasserson TJ, Goldstein RS. Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease. A Cochrane systematic review. Eura MedicoPhys. 2007;43(4): 475–485
  • . O'Donnell DE, Sciurba F, Celli B, . Effect of fluticasone propionate/salmeterol on lung hyperinflation and exercise endurance in COPD. Chest. 2006;130(3):647–656
  • . O'Donnell DE, Laveneziana P, Ora J, Webb KA, Lam YM, Ofir D. Evaluation of acute bronchodilator reversibility in patients with symptoms of GOLD stage I COPD. Thorax. 2009;64(3):216–223
  • . Worth H, Forster K, Eriksson G, Nihlén U, Peterson S, Magnussen H. Budesonide added to formoterol contributes to improved exercise tolerance in patients with COPD. Respir Med. 2010;104(10):1450–1459
  • . Maltais F, Celli B, Casaburi R, . Aclidinium bromide improves exercise endurance and lung hyperinflation in patients with moderate to severe COPD. Respir Med. 2011;105(4):580–587
  • . O'Donnell DE, Casaburi R, Vincken W, . Effect of indacaterol on exercise endurance and lung hyperinflation in COPD. Respir Med. 2011;105(7):1030–1036
  • . Anthonisen NR, Connett JE, Murray RP. Smoking and lung function of Lung Health Study participants after 11 years. Am J Respir Crit Care Med. 2002;166(5):675–679
  • . Scanlon PD, Connett JE, Waller LA, Altose MD, Bailey WC, Buist AS. Smoking cessation and lung function in mild-to-moderate chronic obstructive pulmonary disease. The Lung Health Study. Am J Respir Crit Care Med. 2000;161(2 Pt 1):381–390
  • . Anthonisen NR, Skeans MA, Wise RA, . The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med. 2005;142(4):233–239
  • . Verbanck S, Schuermans D, Paiva M, Meysman M, Vincken W. Small airway function improvement after smoking cessation in smokers without airway obstruction. Am J Respir Crit Care Med. 2006;174(8):853–857
  • . Casaburi R, Maltais F, Porszasz J, . Effects of tiotropium on hyperinflation and treadmill exercise tolerance in mild–moderate chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2014; submitted
  • . Yawn BP. Optimizing chronic obstructive pulmonary disease management in primary care. South Med J. 2011;104(2):121–127
  • . Berry MJ, Rejeski WJ, Adair NE, Zaccaro D. Exercise rehabilitation and chronic obstructive pulmonary disease stage. Am J Respir Crit Care Med. 1999;160(4):1248–1253
  • . Ergun P, Kaymaz D, Gunay E, . Comprehensive out-patient pulmonary rehabilitation: Treatment outcomes in early and late stages of chronic obstructive pulmonary disease. Ann Thorac Med. 2011;6(2):70–76
  • . Tselebis A, Bratis D, Pachi A, . A pulmonary rehabilitation program reduces levels of anxiety and depression in COPD patients. Multidiscip Respir Med. 2013;8(1):41
  • . Jácome CI, Marques AS. Pulmonary rehabilitation for mild chronic obstructive pulmonary disease: a systematic review. Respir Care. 2014;59(4):588–594
  • . Divo M, Pinto-Plata V. Role of exercise in testing and in therapy of COPD. Med Clin North Am. 2012;96(4):753–766
  • . Centers for Medicare and Medicaid Services (CMS), Department of Health and Human Services (HHS). Medicare program; hospital inpatient prospective payment systems for acute care hospitals and the long-term care hospital prospective payment system and Fiscal Year 2014 rates; quality reporting requirements for specific providers; hospital conditions of participation; payment policies related to patient status. Final rules. Fed Regist. 2013;78(160):50495–51040
  • . Medicare Payment Advisory Commission (MedPAC). Report to the Congress: Promoting Greater Efficiency in Medicare. June 2007. http://www.medpac.gov/documents/jun07_entirereport.pdf. Accessed December 5, 2013
  • . Grosso LM, Lindenauer P, Wang C, . Hospital-level 30-day readmission following admission for an acute exacerbation of chronic obstructive pulmonary disease: measure methodology report, Report prepared for the Centers for Medicare and Medicaid Services. September 29, 2011. http://www.qualitynet.org/. Accessed December 5, 2013
  • . Accountable Care Organization 2013 Program Analysis: Quality Performance Standards Narrative Measure Specifications. December 21, 2012. http://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/sharedsavingsprogram/Downloads/ACO-NarrativeMeasures-Specs.pdf. Accessed December 5, 2013
  • . Centers for Medicare and Medicaid Services (CMS), Department of Health and Human Services (HHS). Summary of Final Rule Provisions for Accountable Care Organizations under the Medicare Shared Savings ProgrAm. November 2012. http://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/sharedsavingsprogram/Downloads/ACO_Summary_Factsheet_ICN907404.pdf. Accessed December 5, 2013
  • . O'Donnell DE, Flüge T, Gerken F, . Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD. Eur Respir J. 2004;23(6):832–840
  • . Cooper CB, Dransfield M. Primary care of the patient with chronic obstructive pulmonary disease-part 4: understanding the clinical manifestations of a progressive disease. Am J Med. 2008; 121( 7 Suppl):S33–S45

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