Further advances in the production of membrane proteins in Pichia pastoris

References

• Ramón A, Marín M. Advances in the production of membrane proteins in Pichia pastoris.. Biotechnol J 2011; 6:700 - 6; http://dx.doi.org/10.1002/biot.201100146; PMID: 21567964
   PubMed Web of Science ®Google Scholar
• Lundstrom K. Structural genomics and drug discovery. J Cell Mol Med 2007; 11:224 - 38; http://dx.doi.org/10.1111/j.1582-4934.2007.00028.x; PMID: 17488474
   PubMed Web of Science ®Google Scholar
• Bill RM, Henderson PJ, Iwata S, Kunji ER, Michel H, Neutze R, et al. Overcoming barriers to membrane protein structure determination. Nat Biotechnol 2011; 29:335 - 40; http://dx.doi.org/10.1038/nbt.1833; PMID: 21478852
   PubMed Web of Science ®Google Scholar
• Tate CG. Overexpression of mammalian integral membrane proteins for structural studies. FEBS Lett 2001; 504:94 - 8; http://dx.doi.org/10.1016/S0014-5793(01)02711-9; PMID: 11532439
   PubMed Web of Science ®Google Scholar
• Bonander N, Hedfalk K, Larsson C, Mostad P, Chang C, Gustafsson L, et al. Design of improved membrane protein production experiments: quantitation of the host response. Protein Sci 2005; 14:1729 - 40; http://dx.doi.org/10.1110/ps.051435705; PMID: 15987902
   PubMed Web of Science ®Google Scholar
• Öberg F, Sjöhamn J, Conner MT, Bill RM, Hedfalk K. Improving recombinant eukaryotic membrane protein yields in Pichia pastoris: the importance of codon optimization and clone selection. Mol Membr Biol 2011; 28:398 - 411; http://dx.doi.org/10.3109/09687688.2011.602219; PMID: 21770695
   PubMed Web of Science ®Google Scholar
• Sarramegna V, Demange P, Milon A, Talmont F. Optimizing functional versus total expression of the human mu-opioid receptor in Pichia pastoris.. Protein Expr Purif 2002; 24:212 - 20; http://dx.doi.org/10.1006/prep.2001.1564; PMID: 11858715
   PubMed Web of Science ®Google Scholar
• Weiss HM, Haase W, Michel H, Reiländer H. Comparative biochemical and pharmacological characterization of the mouse 5HT5A 5-hydroxytryptamine receptor and the human beta2-adrenergic receptor produced in the methylotrophic yeast Pichia pastoris.. Biochem J 1998; 330:1137 - 47; PMID: 9494078
   PubMed Web of Science ®Google Scholar
• Oberg F, Ekvall M, Nyblom M, Backmark A, Neutze R, Hedfalk K. Insight into factors directing high production of eukaryotic membrane proteins; production of 13 human AQPs in Pichia pastoris.. Mol Membr Biol 2009; 26:215 - 27; http://dx.doi.org/10.1080/09687680902862085; PMID: 19384754
   PubMed Web of Science ®Google Scholar
• Parker EM, Kameyama K, Higashijima T, Ross EM. Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells. J Biol Chem 1991; 266:519 - 27; PMID: 1845979
   PubMed Web of Science ®Google Scholar
• Issaly N, Solsona O, Joudrier P, Gautier MF, Moulin G, Boze H. Optimization of the wheat puroindoline-a production in Pichia pastoris.. J Appl Microbiol 2001; 90:397 - 406; http://dx.doi.org/10.1046/j.1365-2672.2001.01259.x; PMID: 11298235
   PubMed Web of Science ®Google Scholar
• Su M, Xu T, Wang D, Zhou Y, Niu C, Yan W. High yield and purification of recombinant human apolipoprotein E3 in Pichia pastoris.. Protein Expr Purif 2009; 68:7 - 11; http://dx.doi.org/10.1016/j.pep.2009.06.013; PMID: 19545633
   PubMed Web of Science ®Google Scholar
• Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, et al. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 2009; 323:1718 - 22; http://dx.doi.org/10.1126/science.1168750; PMID: 19325113
   PubMed Web of Science ®Google Scholar
• Brohawn SG, del Mármol J, MacKinnon R. Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel. Science 2012; 335:436 - 41; http://dx.doi.org/10.1126/science.1213808; PMID: 22282805
   PubMed Web of Science ®Google Scholar
• Chen X, Wang Q, Ni F, Ma J. Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement. Proc Natl Acad Sci U S A 2010; 107:11352 - 7; http://dx.doi.org/10.1073/pnas.1000142107; PMID: 20534430
   PubMed Web of Science ®Google Scholar
• Fischer G, Kosinska-Eriksson U, Aponte-Santamaría C, Palmgren M, Geijer C, Hedfalk K, et al. Crystal structure of a yeast aquaporin at 1.15 angstrom reveals a novel gating mechanism. PLoS Biol 2009; 7:e1000130; http://dx.doi.org/10.1371/journal.pbio.1000130; PMID: 19529756
   PubMed Web of Science ®Google Scholar
• Hansen SB, Tao X, MacKinnon R. Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2. Nature 2011; 477:495 - 8; http://dx.doi.org/10.1038/nature10370; PMID: 21874019
   PubMed Web of Science ®Google Scholar
• Hino T, Arakawa T, Iwanari H, Yurugi-Kobayashi T, Ikeda-Suno C, Nakada-Nakura Y, et al. G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody. Nature 2012; 482:237 - 40; PMID: 22286059
   PubMed Web of Science ®Google Scholar
• Ho JD, Yeh R, Sandstrom A, Chorny I, Harries WE, Robbins RA, et al. Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance. Proc Natl Acad Sci U S A 2009; 106:7437 - 42; http://dx.doi.org/10.1073/pnas.0902725106; PMID: 19383790
   PubMed Web of Science ®Google Scholar
• Horsefield R, Nordén K, Fellert M, Backmark A, Törnroth-Horsefield S, Terwisscha van Scheltinga AC, et al. High-resolution x-ray structure of human aquaporin 5. Proc Natl Acad Sci U S A 2008; 105:13327 - 32; http://dx.doi.org/10.1073/pnas.0801466105; PMID: 18768791
   PubMed Web of Science ®Google Scholar
• Hou X, Pedi L, Diver MM, Long SB. Crystal structure of the calcium release-activated calcium channel Orai. Science 2012; 338:1308 - 13; http://dx.doi.org/10.1126/science.1228757; PMID: 23180775
   PubMed Web of Science ®Google Scholar
• Jin MS, Oldham ML, Zhang Q, Chen J. Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans. Nature 2012; 490:566 - 9; http://dx.doi.org/10.1038/nature11448; PMID: 23000902
   PubMed Web of Science ®Google Scholar
• Long SB, Campbell EB, Mackinnon R. Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 2005; 309:897 - 903; http://dx.doi.org/10.1126/science.1116269; PMID: 16002581
   PubMed Web of Science ®Google Scholar
• Long SB, Tao X, Campbell EB, MacKinnon R. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature 2007; 450:376 - 82; http://dx.doi.org/10.1038/nature06265; PMID: 18004376
   PubMed Web of Science ®Google Scholar
• Martinez Molina D, Wetterholm A, Kohl A, McCarthy AA, Niegowski D, Ohlson E, et al. Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase. Nature 2007; 448:613 - 6; http://dx.doi.org/10.1038/nature06009; PMID: 17632546
   PubMed Web of Science ®Google Scholar
• Miller AN, Long SB. Crystal structure of the human two-pore domain potassium channel K2P1. Science 2012; 335:432 - 6; http://dx.doi.org/10.1126/science.1213274; PMID: 22282804
   PubMed Web of Science ®Google Scholar
• Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, et al. Structure of the human histamine H1 receptor complex with doxepin. Nature 2011; 475:65 - 70; http://dx.doi.org/10.1038/nature10236; PMID: 21697825
   PubMed Web of Science ®Google Scholar
• Tao X, Avalos JL, Chen J, MacKinnon R. Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution. Science 2009; 326:1668 - 74; http://dx.doi.org/10.1126/science.1180310; PMID: 20019282
   PubMed Web of Science ®Google Scholar
• Tao X, Lee A, Limapichat W, Dougherty DA, MacKinnon R. A gating charge transfer center in voltage sensors. Science 2010; 328:67 - 73; http://dx.doi.org/10.1126/science.1185954; PMID: 20360102
   PubMed Web of Science ®Google Scholar
• Törnroth-Horsefield S, Wang Y, Hedfalk K, Johanson U, Karlsson M, Tajkhorshid E, et al. Structural mechanism of plant aquaporin gating. Nature 2006; 439:688 - 94; http://dx.doi.org/10.1038/nature04316; PMID: 16340961
   PubMed Web of Science ®Google Scholar
• Whorton MR, MacKinnon R. Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium. Cell 2011; 147:199 - 208; http://dx.doi.org/10.1016/j.cell.2011.07.046; PMID: 21962516
   PubMed Web of Science ®Google Scholar
• Overington JP, Al-Lazikani B, Hopkins AL. How many drug targets are there?. Nat Rev Drug Discov 2006; 5:993 - 6; http://dx.doi.org/10.1038/nrd2199; PMID: 17139284
   PubMed Web of Science ®Google Scholar
• Lebon G, Tate CG. [G protein-coupled receptors in the spotlight]. Med Sci (Paris) 2012; 28:876 - 82; http://dx.doi.org/10.1051/medsci/20122810017; PMID: 23067420
   PubMed Web of Science ®Google Scholar
• Lebon G, Bennett K, Jazayeri A, Tate CG. Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor. J Mol Biol 2011; 409:298 - 310; http://dx.doi.org/10.1016/j.jmb.2011.03.075; PMID: 21501622
   PubMed Web of Science ®Google Scholar
• Serrano-Vega MJ, Magnani F, Shibata Y, Tate CG. Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form. Proc Natl Acad Sci U S A 2008; 105:877 - 82; http://dx.doi.org/10.1073/pnas.0711253105; PMID: 18192400
   PubMed Web of Science ®Google Scholar
• Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG, et al. Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature 2011; 474:521 - 5; http://dx.doi.org/10.1038/nature10136; PMID: 21593763
   PubMed Web of Science ®Google Scholar
• Warne T, Moukhametzianov R, Baker JG, Nehmé R, Edwards PC, Leslie AG, et al. The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor. Nature 2011; 469:241 - 4; http://dx.doi.org/10.1038/nature09746; PMID: 21228877
   PubMed Web of Science ®Google Scholar
• Sarkar CA, Dodevski I, Kenig M, Dudli S, Mohr A, Hermans E, et al. Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity. Proc Natl Acad Sci U S A 2008; 105:14808 - 13; http://dx.doi.org/10.1073/pnas.0803103105; PMID: 18812512
   PubMed Web of Science ®Google Scholar
• Drew D, Newstead S, Sonoda Y, Kim H, von Heijne G, Iwata S. GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae.. Nat Protoc 2008; 3:784 - 98; http://dx.doi.org/10.1038/nprot.2008.44; PMID: 18451787
   PubMed Web of Science ®Google Scholar
• Oberg F, Hedfalk K. Recombinant production of the human aquaporins in the yeast Pichia pastoris (Invited Review). Mol Membr Biol 2013; 30:15 - 31; http://dx.doi.org/10.3109/09687688.2012.665503; PMID: 22908994
   PubMed Web of Science ®Google Scholar
• Singh S, Gras A, Fiez-Vandal C, Martinez M, Wagner R, Byrne B. Screening for high-yielding Pichia pastoris clones: the production of G protein-coupled receptors as a case study. Methods Mol Biol 2012; 866:65 - 73; http://dx.doi.org/10.1007/978-1-61779-770-5_7; PMID: 22454115
   PubMedGoogle Scholar
• Vidan S, Snyder M. Large-scale mutagenesis: yeast genetics in the genome era. Curr Opin Biotechnol 2001; 12:28 - 34; http://dx.doi.org/10.1016/S0958-1669(00)00171-3; PMID: 11167069
   PubMed Web of Science ®Google Scholar
• De Schutter K, Lin YC, Tiels P, Van Hecke A, Glinka S, Weber-Lehmann J, et al. Genome sequence of the recombinant protein production host Pichia pastoris.. Nat Biotechnol 2009; 27:561 - 6; http://dx.doi.org/10.1038/nbt.1544; PMID: 19465926
   PubMed Web of Science ®Google Scholar