Intrinsic properties and regulation of Pannexin 1 channel

References

• Panchin Y, Kelmanson I, Matz M, Lukyanov K, Usman N, Lukyanov S. A ubiquitous family of putative gap junction molecules. Curr Biol 2000; 10:R473 - 4; http://dx.doi.org/10.1016/S0960-9822(00)00576-5; PMID: 10898987
   PubMed Web of Science ®Google Scholar
• Sandilos JK, Bayliss DA. Physiological mechanisms for the modulation of pannexin 1 channel activity. J Physiol 2012; 590:6257 - 66; http://dx.doi.org/10.1113/jphysiol.2012.240911; PMID: 23070703
   PubMed Web of Science ®Google Scholar
• Sorge RE, Trang T, Dorfman R, Smith SB, Beggs S, Ritchie J, Austin JS, Zaykin DV, Vander Meulen H, Costigan M, et al. Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med 2012; 18:595 - 9; http://dx.doi.org/10.1038/nm.2710; PMID: 22447075
   PubMed Web of Science ®Google Scholar
• Penuela S, Gehi R, Laird DW. The biochemistry and function of pannexin channels. Biochim Biophys Acta 2013; 1828:15 - 22; http://dx.doi.org/10.1016/j.bbamem.2012.01.017; PMID: 22305965
   PubMed Web of Science ®Google Scholar
• Karatas H, Erdener SE, Gursoy-Ozdemir Y, Lule S, Eren-Koçak E, Sen ZD, Dalkara T. Spreading depression triggers headache by activating neuronal Panx1 channels. Science 2013; 339:1092 - 5; http://dx.doi.org/10.1126/science.1231897; PMID: 23449592
   PubMed Web of Science ®Google Scholar
• D’hondt C, Ponsaerts R, De Smedt H, Vinken M, De Vuyst E, De Bock M, Wang N, Rogiers V, Leybaert L, Himpens B, et al. Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum. Cell Signal 2011; 23:305 - 16; http://dx.doi.org/10.1016/j.cellsig.2010.07.018; PMID: 20688156
   PubMed Web of Science ®Google Scholar
• Yen MR, Saier MH Jr.. Gap junctional proteins of animals: the innexin/pannexin superfamily. Prog Biophys Mol Biol 2007; 94:5 - 14; http://dx.doi.org/10.1016/j.pbiomolbio.2007.03.006; PMID: 17507077
   PubMed Web of Science ®Google Scholar
• Baranova A, Ivanov D, Petrash N, Pestova A, Skoblov M, Kelmanson I, Shagin D, Nazarenko S, Geraymovych E, Litvin O, et al. The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. Genomics 2004; 83:706 - 16; http://dx.doi.org/10.1016/j.ygeno.2003.09.025; PMID: 15028292
   PubMed Web of Science ®Google Scholar
• Bruzzone R, Hormuzdi SG, Barbe MT, Herb A, Monyer H. Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci U S A 2003; 100:13644 - 9; http://dx.doi.org/10.1073/pnas.2233464100; PMID: 14597722
   PubMed Web of Science ®Google Scholar
• Penuela S, Bhalla R, Gong XQ, Cowan KN, Celetti SJ, Cowan BJ, Bai D, Shao Q, Laird DW. Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. J Cell Sci 2007; 120:3772 - 83; http://dx.doi.org/10.1242/jcs.009514; PMID: 17925379
   PubMedGoogle Scholar
• Panchin YV. Evolution of gap junction proteins--the pannexin alternative. J Exp Biol 2005; 208:1415 - 9; http://dx.doi.org/10.1242/jeb.01547; PMID: 15802665
   PubMed Web of Science ®Google Scholar
• Lai CP, Bechberger JF, Thompson RJ, MacVicar BA, Bruzzone R, Naus CC. Tumor-suppressive effects of pannexin 1 in C6 glioma cells. Cancer Res 2007; 67:1545 - 54; http://dx.doi.org/10.1158/0008-5472.CAN-06-1396; PMID: 17308093
   PubMed Web of Science ®Google Scholar
• Sosinsky GE, Boassa D, Dermietzel R, Duffy HS, Laird DW, MacVicar B, Naus CC, Penuela S, Scemes E, Spray DC, et al. Pannexin channels are not gap junction hemichannels. Channels (Austin) 2011; 5:193 - 7; http://dx.doi.org/10.4161/chan.5.3.15765; PMID: 21532340
   PubMed Web of Science ®Google Scholar
• Dahl G, Keane RW. Pannexin: from discovery to bedside in 11±4 years?. Brain Res 2012; 1487:150 - 9; http://dx.doi.org/10.1016/j.brainres.2012.04.058; PMID: 22771709
   PubMed Web of Science ®Google Scholar
• Bhalla-Gehi R, Penuela S, Churko JM, Shao Q, Laird DW. Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions. J Biol Chem 2010; 285:9147 - 60; http://dx.doi.org/10.1074/jbc.M109.082008; PMID: 20086016
   PubMed Web of Science ®Google Scholar
• Gehi R, Shao Q, Laird DW. Pathways regulating the trafficking and turnover of pannexin1 protein and the role of the C-terminal domain. J Biol Chem 2011; 286:27639 - 53; http://dx.doi.org/10.1074/jbc.M111.260711; PMID: 21659516
   PubMed Web of Science ®Google Scholar
• Boassa D, Ambrosi C, Qiu F, Dahl G, Gaietta G, Sosinsky G. Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane. J Biol Chem 2007; 282:31733 - 43; http://dx.doi.org/10.1074/jbc.M702422200; PMID: 17715132
   PubMed Web of Science ®Google Scholar
• Boassa D, Qiu F, Dahl G, Sosinsky G. Trafficking dynamics of glycosylated pannexin 1 proteins. Cell Commun Adhes 2008; 15:119 - 32; http://dx.doi.org/10.1080/15419060802013885; PMID: 18649184
   PubMed Web of Science ®Google Scholar
• Ambrosi C, Gassmann O, Pranskevich JN, Boassa D, Smock A, Wang J, Dahl G, Steinem C, Sosinsky GE. Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. J Biol Chem 2010; 285:24420 - 31; http://dx.doi.org/10.1074/jbc.M110.115444; PMID: 20516070
   PubMed Web of Science ®Google Scholar
• Wang J, Dahl G. SCAM analysis of Panx1 suggests a peculiar pore structure. J Gen Physiol 2010; 136:515 - 27; http://dx.doi.org/10.1085/jgp.201010440; PMID: 20937692
   PubMed Web of Science ®Google Scholar
• Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, et al. Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis. Nature 2010; 467:863 - 7; http://dx.doi.org/10.1038/nature09413; PMID: 20944749
   PubMed Web of Science ®Google Scholar
• Sandilos JK, Chiu YH, Chekeni FB, Armstrong AJ, Walk SF, Ravichandran KS, Bayliss DA. Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region. J Biol Chem 2012; 287:11303 - 11; http://dx.doi.org/10.1074/jbc.M111.323378; PMID: 22311983
   PubMed Web of Science ®Google Scholar
• Bao L, Locovei S, Dahl G. Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett 2004; 572:65 - 8; http://dx.doi.org/10.1016/j.febslet.2004.07.009; PMID: 15304325
   PubMed Web of Science ®Google Scholar
• Locovei S, Bao L, Dahl G. Pannexin 1 in erythrocytes: function without a gap. Proc Natl Acad Sci U S A 2006; 103:7655 - 9; http://dx.doi.org/10.1073/pnas.0601037103; PMID: 16682648
   PubMed Web of Science ®Google Scholar
• Silverman WR, de Rivero Vaccari JP, Locovei S, Qiu F, Carlsson SK, Scemes E, Keane RW, Dahl G. The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J Biol Chem 2009; 284:18143 - 51; http://dx.doi.org/10.1074/jbc.M109.004804; PMID: 19416975
   PubMed Web of Science ®Google Scholar
• Lohman AW, Weaver JL, Billaud M, Sandilos JK, Griffiths R, Straub AC, Penuela S, Leitinger N, Laird DW, Bayliss DA, et al. S-nitrosylation inhibits pannexin 1 channel function. J Biol Chem 2012; 287:39602 - 12; http://dx.doi.org/10.1074/jbc.M112.397976; PMID: 23033481
   PubMed Web of Science ®Google Scholar
• Billaud M, Lohman AW, Straub AC, Looft-Wilson R, Johnstone SR, Araj CA, Best AK, Chekeni FB, Ravichandran KS, Penuela S, et al. Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction. Circ Res 2011; 109:80 - 5; http://dx.doi.org/10.1161/CIRCRESAHA.110.237594; PMID: 21546608
   PubMed Web of Science ®Google Scholar
• Seminario-Vidal L, Kreda S, Jones L, O’Neal W, Trejo J, Boucher RC, Lazarowski ER. Thrombin promotes release of ATP from lung epithelial cells through coordinated activation of rho- and Ca2+-dependent signaling pathways. J Biol Chem 2009; 284:20638 - 48; http://dx.doi.org/10.1074/jbc.M109.004762; PMID: 19439413
   PubMed Web of Science ®Google Scholar
• Blum AE, Joseph SM, Przybylski RJ, Dubyak GR. Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes. Am J Physiol Cell Physiol 2008; 295:C231 - 41; http://dx.doi.org/10.1152/ajpcell.00175.2008; PMID: 18495810
   PubMedGoogle Scholar
• Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF, Park D, Woodson RI, Ostankovich M, Sharma P, et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 2009; 461:282 - 6; http://dx.doi.org/10.1038/nature08296; PMID: 19741708
   PubMed Web of Science ®Google Scholar
• Qu Y, Misaghi S, Newton K, Gilmour LL, Louie S, Cupp JE, Dubyak GR, Hackos D, Dixit VM. Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation. J Immunol 2011; 186:6553 - 61; http://dx.doi.org/10.4049/jimmunol.1100478; PMID: 21508259
   PubMed Web of Science ®Google Scholar
• Dolmatova E, Spagnol G, Boassa D, Baum JR, Keith K, Ambrosi C, Kontaridis MI, Sorgen PL, Sosinsky GE, Duffy HS. Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation. Am J Physiol Heart Circ Physiol 2012; 303:H1208 - 18; http://dx.doi.org/10.1152/ajpheart.00251.2012; PMID: 22982782
   PubMedGoogle Scholar
• Ma W, Compan V, Zheng W, Martin E, North RA, Verkhratsky A, Surprenant A. Pannexin 1 forms an anion-selective channel. Pflugers Arch 2012; 463:585 - 92; http://dx.doi.org/10.1007/s00424-012-1077-z; PMID: 22311122
   PubMed Web of Science ®Google Scholar
• Romanov RA, Bystrova MF, Rogachevskaya OA, Sadovnikov VB, Shestopalov VI, Kolesnikov SS. The ATP permeability of pannexin 1 channels in a heterologous system and in mammalian taste cells is dispensable. J Cell Sci 2012; 125:5514 - 23; http://dx.doi.org/10.1242/jcs.111062; PMID: 22956545
   PubMed Web of Science ®Google Scholar
• Pelegrin P, Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J 2006; 25:5071 - 82; http://dx.doi.org/10.1038/sj.emboj.7601378; PMID: 17036048
   PubMed Web of Science ®Google Scholar
• Thompson RJ, Jackson MF, Olah ME, Rungta RL, Hines DJ, Beazely MA, MacDonald JF, MacVicar BA. Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. Science 2008; 322:1555 - 9; http://dx.doi.org/10.1126/science.1165209; PMID: 19056988
   PubMed Web of Science ®Google Scholar
• Chung MK, Güler AD, Caterina MJ. Biphasic currents evoked by chemical or thermal activation of the heat-gated ion channel, TRPV3. J Biol Chem 2005; 280:15928 - 41; http://dx.doi.org/10.1074/jbc.M500596200; PMID: 15722340
   PubMed Web of Science ®Google Scholar
• Chung MK, Güler AD, Caterina MJ. TRPV1 shows dynamic ionic selectivity during agonist stimulation. Nat Neurosci 2008; 11:555 - 64; http://dx.doi.org/10.1038/nn.2102; PMID: 18391945
   PubMed Web of Science ®Google Scholar
• Banke TG, Chaplan SR, Wickenden AD. Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation. Am J Physiol Cell Physiol 2010; 298:C1457 - 68; http://dx.doi.org/10.1152/ajpcell.00489.2009; PMID: 20457836
   PubMed Web of Science ®Google Scholar
• Thompson RJ, Zhou N, MacVicar BA. Ischemia opens neuronal gap junction hemichannels. Science 2006; 312:924 - 7; http://dx.doi.org/10.1126/science.1126241; PMID: 16690868
   PubMed Web of Science ®Google Scholar
• Ma W, Hui H, Pelegrin P, Surprenant A. Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther 2009; 328:409 - 18; http://dx.doi.org/10.1124/jpet.108.146365; PMID: 19023039
   PubMed Web of Science ®Google Scholar
• North RA. Molecular physiology of P2X receptors. Physiol Rev 2002; 82:1013 - 67; PMID: 12270951
   PubMed Web of Science ®Google Scholar
• Poornima V, Madhupriya M, Kootar S, Sujatha G, Kumar A, Bera AK. P2X7 receptor-pannexin 1 hemichannel association: effect of extracellular calcium on membrane permeabilization. J Mol Neurosci 2012; 46:585 - 94; http://dx.doi.org/10.1007/s12031-011-9646-8; PMID: 21932038
   PubMed Web of Science ®Google Scholar
• Li S, Tomić M, Stojilkovic SS. Characterization of novel Pannexin 1 isoforms from rat pituitary cells and their association with ATP-gated P2X channels. Gen Comp Endocrinol 2011; 174:202 - 10; http://dx.doi.org/10.1016/j.ygcen.2011.08.019; PMID: 21907716
   PubMed Web of Science ®Google Scholar
• Locovei S, Scemes E, Qiu F, Spray DC, Dahl G. Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett 2007; 581:483 - 8; http://dx.doi.org/10.1016/j.febslet.2006.12.056; PMID: 17240370
   PubMed Web of Science ®Google Scholar
• Iglesias R, Locovei S, Roque A, Alberto AP, Dahl G, Spray DC, Scemes E. P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol 2008; 295:C752 - 60; http://dx.doi.org/10.1152/ajpcell.00228.2008; PMID: 18596211
   PubMed Web of Science ®Google Scholar
• Schachter J, Motta AP, de Souza Zamorano A, da Silva-Souza HA, Guimarães MZ, Persechini PM. ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages. J Cell Sci 2008; 121:3261 - 70; http://dx.doi.org/10.1242/jcs.029991; PMID: 18782864
   PubMed Web of Science ®Google Scholar
• Alberto AV, Faria RX, Couto CG, Ferreira LG, Souza CA, Teixeira PC, Fróes MM, Alves LA. Is pannexin the pore associated with the P2X7 receptor?. Naunyn Schmiedebergs Arch Pharmacol 2013; 386:775 - 87; http://dx.doi.org/10.1007/s00210-013-0868-x; PMID: 23657251
   PubMed Web of Science ®Google Scholar
• Yan Z, Li S, Liang Z, Tomić M, Stojilkovic SS. The P2X7 receptor channel pore dilates under physiological ion conditions. J Gen Physiol 2008; 132:563 - 73; http://dx.doi.org/10.1085/jgp.200810059; PMID: 18852304
   PubMed Web of Science ®Google Scholar
• Chaumont S, Khakh BS. Patch-clamp coordinated spectroscopy shows P2X2 receptor permeability dynamics require cytosolic domain rearrangements but not Panx-1 channels. Proc Natl Acad Sci U S A 2008; 105:12063 - 8; http://dx.doi.org/10.1073/pnas.0803008105; PMID: 18689682
   PubMed Web of Science ®Google Scholar
• Bargiotas P, Krenz A, Hormuzdi SG, Ridder DA, Herb A, Barakat W, Penuela S, von Engelhardt J, Monyer H, Schwaninger M. Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci U S A 2011; 108:20772 - 7; http://dx.doi.org/10.1073/pnas.1018262108; PMID: 22147915
   PubMed Web of Science ®Google Scholar
• Cankurtaran-Sayar S, Sayar K, Ugur M. P2X7 receptor activates multiple selective dye-permeation pathways in RAW 264.7 and human embryonic kidney 293 cells. Mol Pharmacol 2009; 76:1323 - 32; http://dx.doi.org/10.1124/mol.109.059923; PMID: 19749088
   PubMed Web of Science ®Google Scholar
• Xu XJ, Boumechache M, Robinson LE, Marschall V, Gorecki DC, Masin M, Murrell-Lagnado RD. Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1. J Cell Sci 2012; 125:3776 - 89; http://dx.doi.org/10.1242/jcs.099374; PMID: 22553206
   PubMed Web of Science ®Google Scholar
• Locovei S, Wang J, Dahl G. Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium. FEBS Lett 2006; 580:239 - 44; http://dx.doi.org/10.1016/j.febslet.2005.12.004; PMID: 16364313
   PubMed Web of Science ®Google Scholar
• Kanneganti TD, Lamkanfi M, Kim YG, Chen G, Park JH, Franchi L, Vandenabeele P, Núñez G. Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity 2007; 26:433 - 43; http://dx.doi.org/10.1016/j.immuni.2007.03.008; PMID: 17433728
   PubMed Web of Science ®Google Scholar
• Pelegrin P, Barroso-Gutierrez C, Surprenant A. P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J Immunol 2008; 180:7147 - 57; PMID: 18490713
   PubMed Web of Science ®Google Scholar
• Penuela S, Gyenis L, Ablack A, Churko JM, Berger AC, Litchfield DW, Lewis JD, Laird DW. Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype. J Biol Chem 2012; 287:29184 - 93; http://dx.doi.org/10.1074/jbc.M112.377176; PMID: 22753409
   PubMed Web of Science ®Google Scholar
• Suadicani SO, Iglesias R, Wang J, Dahl G, Spray DC, Scemes E. ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes. Glia 2012; 60:1106 - 16; http://dx.doi.org/10.1002/glia.22338; PMID: 22499153
   PubMed Web of Science ®Google Scholar
• Huang YJ, Maruyama Y, Dvoryanchikov G, Pereira E, Chaudhari N, Roper SD. The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc Natl Acad Sci U S A 2007; 104:6436 - 41; http://dx.doi.org/10.1073/pnas.0611280104; PMID: 17389364
   PubMed Web of Science ®Google Scholar
• Romanov RA, Rogachevskaja OA, Bystrova MF, Jiang P, Margolskee RF, Kolesnikov SS. Afferent neurotransmission mediated by hemichannels in mammalian taste cells. EMBO J 2007; 26:657 - 67; http://dx.doi.org/10.1038/sj.emboj.7601526; PMID: 17235286
   PubMed Web of Science ®Google Scholar
• Taruno A, Vingtdeux V, Ohmoto M, Ma Z, Dvoryanchikov G, Li A, Adrien L, Zhao H, Leung S, Abernethy M, et al. CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature 2013; 495:223 - 6; http://dx.doi.org/10.1038/nature11906; PMID: 23467090
   PubMed Web of Science ®Google Scholar
• Siebert AP, Ma Z, Grevet JD, Demuro A, Parker I, Foskett JK. Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins. J Biol Chem 2013; 288:6140 - 53; http://dx.doi.org/10.1074/jbc.M112.409789; PMID: 23300080
   PubMed Web of Science ®Google Scholar
• Qiu F, Dahl G. A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP. Am J Physiol Cell Physiol 2009; 296:C250 - 5; http://dx.doi.org/10.1152/ajpcell.00433.2008; PMID: 18945939
   PubMed Web of Science ®Google Scholar
• Hanner F, Lam L, Nguyen MT, Yu A, Peti-Peterdi J. Intrarenal localization of the plasma membrane ATP channel pannexin1. Am J Physiol Renal Physiol 2012; 303:F1454 - 9; http://dx.doi.org/10.1152/ajprenal.00206.2011; PMID: 22952282
   PubMedGoogle Scholar
• Prochnow N, Abdulazim A, Kurtenbach S, Wildförster V, Dvoriantchikova G, Hanske J, Petrasch-Parwez E, Shestopalov VI, Dermietzel R, Manahan-Vaughan D, et al. Pannexin1 stabilizes synaptic plasticity and is needed for learning. PLoS One 2012; 7:e51767; http://dx.doi.org/10.1371/journal.pone.0051767; PMID: 23284764
   PubMedGoogle Scholar
• Santiago MF, Veliskova J, Patel NK, Lutz SE, Caille D, Charollais A, Meda P, Scemes E. Targeting pannexin1 improves seizure outcome. PLoS One 2011; 6:e25178; http://dx.doi.org/10.1371/journal.pone.0025178; PMID: 21949881
   PubMed Web of Science ®Google Scholar
• Duan S, Anderson CM, Keung EC, Chen Y, Chen Y, Swanson RA. P2X7 receptor-mediated release of excitatory amino acids from astrocytes. J Neurosci 2003; 23:1320 - 8; PMID: 12598620
   PubMed Web of Science ®Google Scholar
• Jiang H, Zhu AG, Mamczur M, Falck JR, Lerea KM, McGiff JC. Stimulation of rat erythrocyte P2X7 receptor induces the release of epoxyeicosatrienoic acids. Br J Pharmacol 2007; 151:1033 - 40; http://dx.doi.org/10.1038/sj.bjp.0707311; PMID: 17558440
   PubMed Web of Science ®Google Scholar
• Spangler SG. Expansion of the constant field equation to include both divalent and monovalent ions. Ala J Med Sci 1972; 9:218 - 23; PMID: 5045041
   PubMedGoogle Scholar