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Research Article
Development of new thiazolidine-2,4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: design, synthesis, biological investigations, and in silico insights
Abdelrahman Hamdia Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptCorrespondence[email protected]
https://orcid.org/0000-0002-0196-1976View further author information
Muhammad Yaseenb Institute of Chemical Sciences, University of Swat, Swat, PakistanCorrespondence[email protected]
https://orcid.org/0000-0002-2259-4589View further author information
Wafaa A. Ewesa Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
https://orcid.org/0000-0001-7690-2906View further author information
Mashooq Ahmad Bhatc Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
https://orcid.org/0000-0001-8426-4692View further author information
Noha I. Ziedand Department of physical, mathematical and Engineering science, Faculty of science, Business and Enterprise, University of Chester, Chester, UK
https://orcid.org/0000-0002-9522-2188View further author information
Hamed W. El-Shafeya Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
https://orcid.org/0000-0002-7848-8785View further author information
Ahmed A. B. Mohamede Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
https://orcid.org/0000-0003-3912-1021View further author information
Mohamed R. Elnagarf Pharmacology and Toxicology Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt;g Department of Pharmacology, College of Pharmacy, The Islamic University, Najaf, Iraq
https://orcid.org/0000-0003-0434-2369View further author information
Abdullah Haikalh Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
https://orcid.org/0000-0003-2548-3507View further author information
Dina I. A. Othmana Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptView further author information
, Abdullah A. Elgazari Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt
https://orcid.org/0000-0002-5851-3306View further author information
Ahmed H. A. Abusabaaj Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, Fayoum University, Fayoum, Egypt
https://orcid.org/0009-0000-3770-4042View further author information
Kamal S. Abdelrahmank Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt
https://orcid.org/0000-0002-2661-6159View further author information
Osama M. Soltank Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt
https://orcid.org/0000-0001-9738-2436View further author information
Mostafa M. Elbadawil Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt
https://orcid.org/0000-0002-9073-4176View further author information
Article: 2231170
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Received 24 May 2023, Accepted 25 Jun 2023, Published online: 20 Jul 2023
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