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Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 6
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General Xenobiochemistry

In vitro inhibition and enhancement of liver microsomal S-777469 metabolism by long-chain fatty acids and serum albumin: insight into in vitro and in vivo discrepancy of metabolite formation in humans

Kazutaka SekiguchiDrug Metabolism & Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Osaka, Japan and Correspondence[email protected]
,
Takushi KanazuDrug Metabolism & Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Osaka, Japan and
,
Norie MurayamaLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan
,
Hiroshi YamazakiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan
&
Yoshitaka YamaguchiDrug Metabolism & Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Osaka, Japan and
Pages 495-502 | Received 04 Aug 2015, Accepted 02 Sep 2015, Published online: 18 Dec 2015

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