The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events

Ted W. SimonTed Simon LLC, Winston, GA, USA

S. Stoney Simons Jr.Steroid Hormones Section, NIDDK/LERB, National Institutes of Health, Bethesda, MD, USA

R. Julian PrestonU.S. EPA/National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC, USA

Alan R. BoobisImperial College London, London, UK

Samuel M. CohenUniversity of Nebraska Medical Center, Omaha, NE, USA

Nancy G. DoerrerILSI Health and Environmental Sciences Institute, Washington, DC, USACorrespondence[email protected]

Penelope A. Fenner-CrispConsultant, North Garden, VA, USA

Tami S. McMullinDow Corning, Midland, MI, USA

Charlene A. McQueenU.S. EPA/National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC, USA

J. Craig RowlandsThe Dow Chemical Company, Toxicology and Environmental Research & Consulting, Midland, MI, USA

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