Cancer Management and Research: Vol 10, No

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Original Research

Article

Programmed death-ligand 1 expression correlates with diminished CD8+ T cell infiltration and predicts poor prognosis in anal squamous cell carcinoma patients

Yu-Jie Zhao, Wei-Peng Sun, Jian-Hong Peng, Yu-Xiang Deng, Yu-Jing Fang, Jun Huang, Hui-Zhong Zhang, De-Sen Wan, Jun-Zhong Lin & Zhi-Zhong Pan

Pages: 1-11

Published online: 18 Dec 2017

AbstractforProgrammed death-ligand 1 expression correlates with diminished CD8+ T cell infiltration and predicts poor prognosis in anal squamous cell carcinoma patients | Full Text | References | PDF (7.8 MB)

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Review

Review Article

Radiotherapy for esophageal carcinoma: dose, response and survival

Yijun Luo, Qingfeng Mao, Xiaoli Wang, Jinming Yu & Minghuan Li

Pages: 13-21

Published online: 29 Dec 2017

AbstractforRadiotherapy for esophageal carcinoma: dose, response and survival | Full Text | References | PDF (428.5 KB)

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Original Research

Article

Effects of marital status on survival of hepatocellular carcinoma by race/ethnicity and gender

Wenrui Wu, Daiqiong Fang, Ding Shi, Xiaoyuan Bian & Lanjuan Li

Pages: 23-32

Published online: 03 Jan 2018

AbstractforEffects of marital status on survival of hepatocellular carcinoma by race/ethnicity and gender | Full Text | References | PDF (932.8 KB)

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Article

The reciprocal relationship between coping mechanisms and lung cancer diagnosis: findings of a prospective study

Cristian Oancea, Cristian Suciu, Bogdan Timar, Ion Papava, Marius Raica & Ovidiu Burlacu

Pages: 33-40

Published online: 04 Jan 2018

AbstractforThe reciprocal relationship between coping mechanisms and lung cancer diagnosis: findings of a prospective study | Full Text | References | PDF (482.2 KB)

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Article

Young age increases risk for lymph node positivity but decreases risk for non-small cell lung cancer death

Wenjie Xia, Anpeng Wang, Meng Jin, Qixing Mao, Wenying Xia, Gaochao Dong, Bing Chen, Weidong Ma, Lin Xu & Feng Jiang

Pages: 41-48

Published online: 08 Jan 2018

AbstractforYoung age increases risk for lymph node positivity but decreases risk for non-small cell lung cancer death | Full Text | References | PDF (675 KB)

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Article

Detection of circulating tumor cells in liquid biopsy from Ewing sarcoma patients

Stefania Benini, Gabriella Gamberi, Stefania Cocchi, Jessica Garbetta, Laurent Alberti, Alberto Righi, Marco Gambarotti, Piero Picci & Stefano Ferrari

Pages: 49-60

Published online: 09 Jan 2018

AbstractforDetection of circulating tumor cells in liquid biopsy from Ewing sarcoma patients | Full Text | References | PDF (5 MB)

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Review

Review Article

Vulvar carcinoma: dilemma, debates, and decisions

Swarupa Mitra, Manoj Kumar Sharma, Inderjeet Kaur, Ruparna Khurana, Kanika Batra Modi, Raman Narang, Avik Mandal & Soumya Dutta

Pages: 61-68

Published online: 09 Jan 2018

AbstractforVulvar carcinoma: dilemma, debates, and decisions | Full Text | References | PDF (159.9 KB)

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Review Article

Toxic elements as biomarkers for breast cancer: a meta-analysis study

Leila Jouybari, Marzieh Saei Ghare Naz, Akram Sanagoo, Faezeh Kiani, Fatemeh Sayehmiri, Kourosh Sayehmiri & Ali Hasanpour Dehkordi

Pages: 69-79

Published online: 10 Jan 2018

AbstractforToxic elements as biomarkers for breast cancer: a meta-analysis study | Full Text | References | PDF (778.9 KB)

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Review Article

The potential role of angiogenesis in the development of shoulder pain, shoulder dysfunction, and lymphedema after breast cancer treatment

Trevor S Mafu, Alison V September & Delva Shamley

Pages: 81-90

Published online: 15 Jan 2018

AbstractforThe potential role of angiogenesis in the development of shoulder pain, shoulder dysfunction, and lymphedema after breast cancer treatment | Full Text | References | PDF (463.7 KB)

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Review Article

Neoadjuvant treatments in triple-negative breast cancer patients: where we are now and where we are going

Claudia Omarini, Giorgia Guaitoli, Stefania Pipitone, Luca Moscetti, Laura Cortesi, Stefano Cascinu & Federico Piacentini

Pages: 91-103

Published online: 15 Jan 2018

AbstractforNeoadjuvant treatments in triple-negative breast cancer patients: where we are now and where we are going | Full Text | References | PDF (554.3 KB)

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Original Research

Article

The relationship between the PD-1/PD-L1 pathway and DNA mismatch repair in cervical cancer and its clinical significance

Yang-chun Feng, Wen-li Ji, Na Yue, Yan-chun Huang & Xiu-min Ma

Pages: 105-113

Published online: 18 Jan 2018

AbstractforThe relationship between the PD-1/PD-L1 pathway and DNA mismatch repair in cervical cancer and its clinical significance | Full Text | References | PDF (5.7 MB)

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Article

A comparison of QuantStudio™ 3D Digital PCR and ARMS-PCR for measuring plasma EGFR T790M mutations of NSCLC patients

Qin Feng, Fei Gai, Yaxiong Sang, Jie Zhang, Ping Wang, Yue Wang, Bing Liu, Dongmei Lin, Yang Yu & Jian Fang

Pages: 115-121

Published online: 18 Jan 2018

AbstractforA comparison of QuantStudio™ 3D Digital PCR and ARMS-PCR for measuring plasma EGFR T790M mutations of NSCLC patients | Full Text | References | PDF (229.1 KB)

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Review

Review Article

The role of brigatinib in crizotinib-resistant non-small cell lung cancer

Laura Mezquita & David Planchard

Pages: 123-130

Published online: 18 Jan 2018

AbstractforThe role of brigatinib in crizotinib-resistant non-small cell lung cancer | Full Text | References | PDF (155.6 KB)

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Original Research

Article

Radiation-induced secondary malignancies for nasopharyngeal carcinoma: a pilot study of patients treated via IMRT or VMAT

Hsiao-Fei Lee, Jen-Hong Lan, Pei-Ju Chao, Hui-Min Ting, Hui-Chun Chen, Hsuan-Chih Hsu & Tsair-Fwu Lee

Pages: 131-141

Published online: 18 Jan 2018

AbstractforRadiation-induced secondary malignancies for nasopharyngeal carcinoma: a pilot study of patients treated via IMRT or VMAT | Full Text | References | PDF (1.6 MB)

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Article

Association between body mass index and breast cancer risk: evidence based on a dose–response meta-analysis

Kang Liu, Weining Zhang, Zhiming Dai, Meng Wang, Tian Tian, Xinghan Liu, Huafeng Kang, Haitao Guan, Shuqun Zhang & Zhijun Dai

Pages: 143-151

Published online: 18 Jan 2018

AbstractforAssociation between body mass index and breast cancer risk: evidence based on a dose–response meta-analysis | Full Text | References | PDF (1,001.6 KB)

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Review

Review Article

Solute carrier transporters: potential targets for digestive system neoplasms

Jing Xie, Xiao Yan Zhu, Lu Ming Liu & Zhi Qiang Meng

Pages: 153-166

Published online: 24 Jan 2018

AbstractforSolute carrier transporters: potential targets for digestive system neoplasms | Full Text | References | PDF (3.1 MB)

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Original Research

Article

Treatment and outcomes of non-small-cell lung cancer patients with high comorbidity

Jorge Rios, Rahul Gosain, Bernardo HL Goulart, Bin Huang, Margaret N Oechsli, Jaclyn K McDowell, Quan Chen, Thomas Tucker & Goetz H Kloecker

Pages: 167-175

Published online: 24 Jan 2018

AbstractforTreatment and outcomes of non-small-cell lung cancer patients with high comorbidity | Full Text | References | PDF (649.7 KB)

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Case Report

Adrenal myelolipoma with hyperandrogenemia and schizophrenia

Ningning Liu, Wenhua Zhang, Jiangshan Tan, Jiaxin Zhou, Xiaopeng Yu, Ningxin Ren, Zhiqing Fang, Wei Jiao, Yidong Fan & Cheng Liu

Pages: 177-180

Published online: 01 Feb 2018

AbstractforAdrenal myelolipoma with hyperandrogenemia and schizophrenia | Full Text | References | PDF (1.6 MB)

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Original Research

Article

Early diagnostic potential of APC hypermethylation in esophageal cancer

Bujiang Wang, Haojun Song, Haizhong Jiang, Yangbo Fu, Xiaoyun Ding & Chongchang Zhou

Pages: 181-198

Published online: 01 Feb 2018

AbstractforEarly diagnostic potential of APC hypermethylation in esophageal cancer | Full Text | References | PDF (3.3 MB)

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Review

Review Article

Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review

Shuwen Han, Jianlan Gao, Qing Zhou, Shanshan Liu, Caixia Wen & Xi Yang

Pages: 199-206

Published online: 31 Jan 2018

AbstractforRole of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review | Full Text | References | PDF (1.2 MB)

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Review Article

Advances in the treatment of soft tissue sarcoma: focus on eribulin

Panagiotis Koliou, Vasilios Karavasilis, Maria Theochari, Seth M Pollack, Robin L Jones & Khin Thway

Pages: 207-216

Published online: 01 Feb 2018

AbstractforAdvances in the treatment of soft tissue sarcoma: focus on eribulin | Full Text | References | PDF (470.3 KB)

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Original Research

Article

Influential factors on radiotherapy efficacy and prognosis in patients with secondary lymph node metastasis after esophagectomy of thoracic esophageal squamous cell carcinoma

Shao-Bing Zhou, Xin-Wei Guo, Liang Gu & Sheng-Jun Ji

Pages: 217-225

Published online: 02 Feb 2018

AbstractforInfluential factors on radiotherapy efficacy and prognosis in patients with secondary lymph node metastasis after esophagectomy of thoracic esophageal squamous cell carcinoma | Full Text | References | PDF (1.1 MB)

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Article

Comparison of prognostic prediction between nomogram based on lymph node ratio and AJCC 8th staging system for patients with resected pancreatic head carcinoma: a SEER analysis

Ning Pu, Jianang Li, Yaolin Xu, Wanling Lee, Yuan Fang, Xu Han, Guochao Zhao, Lei Zhang, Abulimiti Nuerxiati, Hanlin Yin, Wenchuan Wu & Wenhui Lou

Pages: 227-238

Published online: 05 Feb 2018

AbstractforComparison of prognostic prediction between nomogram based on lymph node ratio and AJCC 8th staging system for patients with resected pancreatic head carcinoma: a SEER analysis | Full Text | References | PDF (1.4 MB)

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Review

Review Article

Gastric cancer: epidemiology, prevention, classification, and treatment

Robert Sitarz, Małgorzata Skierucha, Jerzy Mielko, G Johan A Offerhaus, Ryszard Maciejewski & Wojciech P Polkowski

Pages: 239-248

Published online: 07 Feb 2018

AbstractforGastric cancer: epidemiology, prevention, classification, and treatment | Full Text | References | PDF (675.1 KB)

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Original Research

Article

Comparative effectiveness of early-line nab-paclitaxel vs. paclitaxel in patients with metastatic breast cancer: a US community-based real-world analysis

Reshma L Mahtani, Monika Parisi, Stefan Glück, Quanhong Ni, Siyeon Park, Corey Pelletier, Claudio Faria & Fadi Braiteh

Pages: 249-256

Published online: 08 Feb 2018

AbstractforComparative effectiveness of early-line nab-paclitaxel vs. paclitaxel in patients with metastatic breast cancer: a US community-based real-world analysis | Full Text | References | PDF (492.7 KB)

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Article

Anastomotic reinforcement with omentoplasty reduces anastomotic leakage for minimally invasive esophagectomy with cervical anastomosis

Dong Zhou, Quan-Xing Liu, Xu-Feng Deng, Hong Zheng, Xiao Lu, Ji-Gang Dai & Li Jiang

Pages: 257-263

Published online: 07 Feb 2018

AbstractforAnastomotic reinforcement with omentoplasty reduces anastomotic leakage for minimally invasive esophagectomy with cervical anastomosis | Full Text | References | PDF (1.5 MB)

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Article

Uncemented three-dimensional-printed prosthetic replacement for giant cell tumor of distal radius: a new design of prosthesis and surgical techniques

Minxun Lu, Li Min, Cong Xiao, Yongjiang Li, Yi Luo, Yong Zhou, Wenli Zhang & Chongqi Tu

Pages: 265-277

Published online: 08 Feb 2018

AbstractforUncemented three-dimensional-printed prosthetic replacement for giant cell tumor of distal radius: a new design of prosthesis and surgical techniques | Full Text | References | PDF (18.4 MB)

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Article

Neoadjuvant chemotherapy among patients treated for nonmetastatic breast cancer in a population with a high HIV prevalence in Johannesburg, South Africa

Paul Ruff, Herbert Cubasch, Maureen Joffe, Evan Rosenbaum, Nivashni Murugan, Ming-Chih Tsai, Oluwatosin Ayeni, Katherine D Crew, Judith S Jacobson & Alfred I Neugut

Pages: 279-286

Published online: 09 Feb 2018

AbstractforNeoadjuvant chemotherapy among patients treated for nonmetastatic breast cancer in a population with a high HIV prevalence in Johannesburg, South Africa | Full Text | References | PDF (205.8 KB)

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Article

Bone metastasis pattern in initial metastatic breast cancer: a population-based study

Zhenchong Xiong, Guangzheng Deng, Xinjian Huang, Xing Li, Xinhua Xie, Jin Wang, Zeyu Shuang & Xi Wang

Pages: 287-295

Published online: 09 Feb 2018

AbstractforBone metastasis pattern in initial metastatic breast cancer: a population-based study | Full Text | References | PDF (755.4 KB)

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Article

Husbands’ perceptions of their wives’ breast cancer coping efficacy: testing congruence models of adjustment

Thomas V Merluzzi & MaryAnn Martinez Sanchez

Pages: 297-304

Published online: 12 Feb 2018

AbstractforHusbands’ perceptions of their wives’ breast cancer coping efficacy: testing congruence models of adjustment | Full Text | References | PDF (159.4 KB)

74 Views
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Article

The role of cytokines and chemokines in the microenvironment of the blood–brain barrier in leukemia central nervous system metastasis

Mengya Si, Xiaoyang Jiao, Yazhen Li, Huanzhu Chen, Ping He & Fang Jiang

Pages: 305-313

Published online: 12 Feb 2018

AbstractforThe role of cytokines and chemokines in the microenvironment of the blood–brain barrier in leukemia central nervous system metastasis | Full Text | References | PDF (3.1 MB)

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Article

Combination of CRP and NLR: a better predictor of postoperative survival in patients with gastric cancer

Jing Guo, Shangxiang Chen, Yongming Chen, Shun Li & Dazhi Xu

Pages: 315-321

Published online: 14 Feb 2018

AbstractforCombination of CRP and NLR: a better predictor of postoperative survival in patients with gastric cancer | Full Text | References | PDF (997.5 KB)

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Article

RETRACTED ARTICLE: The role of calgranulin B gene on the biological behavior of squamous cervical cancer in vitro and in vivo

Wenwen Zhang, Miaomiao Chen, Huihui Cheng, Qi Shen, Ying Wang & Xueqiong Zhu

Pages: 323-338

Published online: 16 Feb 2018

AbstractforRETRACTED ARTICLE: The role of calgranulin B gene on the biological behavior of squamous cervical cancer in vitro and in vivo | PDF (5.7 MB)

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Article

MicroRNA–mRNA expression profiles associated with medulloblastoma subgroup 4

Sivan Gershanov, Helen Toledano, Shalom Michowiz, Orit Barinfeld, Albert Pinhasov, Nitza Goldenberg-Cohen & Mali Salmon-Divon

Pages: 339-352

Published online: 16 Feb 2018

AbstractforMicroRNA–mRNA expression profiles associated with medulloblastoma subgroup 4 | Full Text | References | PDF (3.9 MB)

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Article

Patients with osteosarcoma and soft tissue sarcoma might become “cancer refugees” in some Japanese regional cities

Hiromichi Yamane, Toshiyuki Kunisada, Toshifumi Ozaki, Nobuaki Ochi, Yoshihiro Honda, Yasunari Nagasaki, Nozomu Nakagawa, Tomoko Yamagishi, Hidekazu Nakanishi & Nagio Takigawa

Pages: 353-359

Published online: 19 Feb 2018

AbstractforPatients with osteosarcoma and soft tissue sarcoma might become “cancer refugees” in some Japanese regional cities | Full Text | References | PDF (1.4 MB)

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Article

Surgical resection improves long-term survival of patients with hepatocellular carcinoma across different Barcelona Clinic Liver Cancer stages

Hui Guo, Tao Wu, Qiang Lu, Miaojing Li, Jing-Yue Guo, Yuan Shen, Zheng Wu, Ke-Jun Nan, Yi Lv & Xu-Feng Zhang

Pages: 361-369

Published online: 21 Feb 2018

AbstractforSurgical resection improves long-term survival of patients with hepatocellular carcinoma across different Barcelona Clinic Liver Cancer stages | Full Text | References | PDF (848.4 KB)

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Article

High C-reactive protein/albumin ratio predicts unfavorable distant metastasis-free survival in nasopharyngeal carcinoma: a propensity score-matched analysis

Yan Wang, Lin Yang, Liangping Xia & Yong Chen

Pages: 371-381

Published online: 21 Feb 2018

AbstractforHigh C-reactive protein/albumin ratio predicts unfavorable distant metastasis-free survival in nasopharyngeal carcinoma: a propensity score-matched analysis | Full Text | References | PDF (827.5 KB)

178 Views
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Article

Quality of life of young Chinese breast cancer patients after adjuvant chemotherapy

Winnie Yeo, Frankie KF Mo, Elizabeth Pang, Joyce JS Suen, Jane Koh, Claudia HW Yip, Christopher CH Yip, Leung Li, Herbert HF Loong & Giok S Liem

Pages: 383-389

Published online: 22 Feb 2018

AbstractforQuality of life of young Chinese breast cancer patients after adjuvant chemotherapy | Full Text | References | PDF (148.2 KB)

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Article

Coordination of FOXA2 and SIRT6 suppresses the hepatocellular carcinoma progression through ZEB2 inhibition

Jinghua Liu, Zhen Yu, Yuanyuan Xiao, Qiong Meng, Yeying Wang & Wei Chang

Pages: 391-402

Published online: 01 Mar 2018

AbstractforCoordination of FOXA2 and SIRT6 suppresses the hepatocellular carcinoma progression through ZEB2 inhibition | Full Text | References | PDF (3.4 MB)

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Article

Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy?

Bibi Kulsoom, Tahir Sultan Shamsi, Nasir Ali Afsar, Zahida Memon, Nikhat Ahmed & Syed Nazrul Hasnain

Pages: 403-416

Published online: 02 Mar 2018

AbstractforBax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy? | Full Text | References | PDF (1 MB)

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Article

A novel mechanism of tumor-induced thymic atrophy in mice bearing H22 hepatocellular carcinoma

Sujun Sun, Haiyu Ji, Yingying Feng, Yu Kang, Juan Yu & Anjun Liu

Pages: 417-424

Published online: 05 Mar 2018

AbstractforA novel mechanism of tumor-induced thymic atrophy in mice bearing H22 hepatocellular carcinoma | Full Text | References | PDF (2.6 MB)

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Review

Review Article

Evolution of regorafenib from bench to bedside in colorectal cancer: Is it an attractive option or merely a “me too” drug?

Gaurav Goel

Pages: 425-437

Published online: 06 Mar 2018

AbstractforEvolution of regorafenib from bench to bedside in colorectal cancer: Is it an attractive option or merely a “me too” drug? | Full Text | References | PDF (939.7 KB)

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Original Research

Article

Adenosquamous carcinoma of the bile duct: a population-based study

Bao-Dong Qin, Xiao-Dong Jiao, Ling-Yan Yuan, Ke Liu & Yuan-Sheng Zang

Pages: 439-446

Published online: 07 Mar 2018

AbstractforAdenosquamous carcinoma of the bile duct: a population-based study | Full Text | References | PDF (638.9 KB)

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Article

Optimized multiparametric flow cytometric analysis of circulating endothelial cells and their subpopulations in peripheral blood of patients with solid tumors: a technical analysis

Fangbin Zhou, Yaying Zhou, Ming Yang, Jinli Wen, Jun Dong & Wenyong Tan

Pages: 447-464

Published online: 08 Mar 2018

AbstractforOptimized multiparametric flow cytometric analysis of circulating endothelial cells and their subpopulations in peripheral blood of patients with solid tumors: a technical analysis | Full Text | References | PDF (4.9 MB)

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Article

Clinical behaviors of rare variants of papillary thyroid carcinoma are associated with survival: a population-level analysis

Chenghao Jiang, Tong Cheng, Xucai Zheng, Shikai Hong, Song Liu, Jianjun Liu, Jing Wang & Shengying Wang

Pages: 465-472

Published online: 09 Mar 2018

AbstractforClinical behaviors of rare variants of papillary thyroid carcinoma are associated with survival: a population-level analysis | Full Text | References | PDF (467 KB)

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Article

Moderate hypofractionated radiotherapy after prostatectomy for cancer patients: toxicity and clinical outcome

Salvina Barra, Liliana Belgioia, Michela Marcenaro, Serena Callegari, Alice Pastorino, Luca Trapani, Francesca Cavagnetto, Stefania Garelli & Renzo Corvò

Pages: 473-480

Published online: 12 Mar 2018

AbstractforModerate hypofractionated radiotherapy after prostatectomy for cancer patients: toxicity and clinical outcome | Full Text | References | PDF (322.7 KB)

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Article

Intensity of treatment in Swiss cancer patients at the end-of-life

Caroline Bähler, Andri Signorell, Eva Blozik & Oliver Reich

Pages: 481-491

Published online: 15 Mar 2018

AbstractforIntensity of treatment in Swiss cancer patients at the end-of-life | Full Text | References | PDF (368.6 KB)

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Article

Immunocompetence and mechanism of the DRibble-DCs vaccine for oral squamous cell carcinoma

Heng Dong, Hang Su, Lin Chen, Kai Liu, Hong-ming Hu, Weidong Yang & Yongbin Mou

Pages: 493-501

Published online: 16 Mar 2018

AbstractforImmunocompetence and mechanism of the DRibble-DCs vaccine for oral squamous cell carcinoma | Full Text | References | PDF (2.4 MB)

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Article

Upregulation of Arp2 expression is associated with the prognosis and prediction of lymph node metastasis in bladder urothelial carcinoma

Ning Xu, Gen-Yi Qu, Yu-Peng Wu, Xiao-Dong Li, Min-Yi Lin, Shao-Hao Chen, Xue-Yi Xue & Yong Wei

Pages: 503-511

Published online: 19 Mar 2018

AbstractforUpregulation of Arp2 expression is associated with the prognosis and prediction of lymph node metastasis in bladder urothelial carcinoma | Full Text | References | PDF (3.1 MB)

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Case Report

Primary clear cell carcinoma of the thymus and literature comparison of features

Xiaomin Dai, Li Zhao & Fang Peng

Pages: 513-518

Published online: 16 Mar 2018

AbstractforPrimary clear cell carcinoma of the thymus and literature comparison of features | Full Text | References | PDF (4 MB)

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Original Research

Article

Prospective study of neoadjuvant chemoradiotherapy using intensity-modulated radiotherapy and 5 fluorouracil for locally advanced rectal cancer – toxicities and response assessment

David K Simson, Swarupa Mitra, Parveen Ahlawat, Upasna Saxena, Manoj Kumar Sharma, Sheh Rawat, Harpreet Singh, Babita Bansal, Lalitha Kameshwari Sripathi & Aditi Tanwar

Pages: 519-526

Published online: 19 Mar 2018

AbstractforProspective study of neoadjuvant chemoradiotherapy using intensity-modulated radiotherapy and 5 fluorouracil for locally advanced rectal cancer – toxicities and response assessment | Full Text | References | PDF (349.3 KB)

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Article

Prognostic value of ductal carcinoma in situ component in invasive ductal carcinoma of the breast: a Surveillance, Epidemiology, and End Results database analysis

San-Gang Wu, Wen-Wen Zhang, Jia-Yuan Sun & Zhen-Yu He

Pages: 527-534

Published online: 19 Mar 2018

AbstractforPrognostic value of ductal carcinoma in situ component in invasive ductal carcinoma of the breast: a Surveillance, Epidemiology, and End Results database analysis | Full Text | References | PDF (398.1 KB)

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Article

Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3

Juan Zhou, Wen-Wen Zhang, Fang Peng, Jia-Yuan Sun, Zhen-Yu He & San-Gang Wu

Pages: 535-544

Published online: 19 Mar 2018

AbstractforDownregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3 | Full Text | References | PDF (2 MB)

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Article

Mechanical ventilation promotes lung metastasis in experimental 4T1 breast cancer lung-metastasized models

Yinglai Huang, Lin Pan, Khalil Helou, Qisheng Xia, Toshima Z Parris, Hongyan Li, Bo Xu & Hon Li

Pages: 545-555

Published online: 20 Mar 2018

AbstractforMechanical ventilation promotes lung metastasis in experimental 4T1 breast cancer lung-metastasized models | Full Text | References | PDF (4.6 MB)

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Article

Management and prognosis of patients with liver metastases from gestational trophoblastic neoplasia: a retrospective cohort study

Liju Zong, Junjun Yang, Xiaoyu Wang, Yujia Kong, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan & Yang Xiang

Pages: 557-563

Published online: 23 Mar 2018

AbstractforManagement and prognosis of patients with liver metastases from gestational trophoblastic neoplasia: a retrospective cohort study | Full Text | References | PDF (317.6 KB)

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Article

L61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway

Encheng Bai, Lehe Yang, Youqun Xiang, Wanle Hu, Caleb Li, Jiayuh Lin, Xuanxuan Dai, Guang Liang, Rong Jin & Chengguang Zhao

Pages: 565-581

Published online: 23 Mar 2018

AbstractforL61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway | Full Text | References | PDF (9.5 MB)

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Case Series

Bimodality treatment of patients with pelvic adenoid cystic carcinoma with photon intensity-modulated radiotherapy plus carbon ion boost: a case series

Denise Bernhardt, Florian Sterzing, Sebastian Adeberg, Klaus Herfarth, Sonja Katayama, Robert Foerster, Juliane Hoerner-Rieber, Laila König, Juergen Debus & Stefan Rieken

Pages: 583-588

Published online: 26 Mar 2018

AbstractforBimodality treatment of patients with pelvic adenoid cystic carcinoma with photon intensity-modulated radiotherapy plus carbon ion boost: a case series | Full Text | References | PDF (3.5 MB)

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Original Research

Article

SYK expression level distinguishes control from BRCA1-mutated lymphocytes

Tamar Zahavi, Amir Sonnenblick, Yael Shimshon, Luna Kadouri, Tamar Peretz, Asher Y Salmon & Mali Salmon-Divon

Pages: 589-598

Published online: 26 Mar 2018

AbstractforSYK expression level distinguishes control from BRCA1-mutated lymphocytes | Full Text | References | PDF (1.7 MB)

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Article

The mutation of hepatitis B virus and the prognosis of hepatocellular carcinoma after surgery: a pilot study

Yaojun Zhang, Junting Huang, Jinbin Chen, Keli Yang, Jiancong Chen, Li Xu, Zhongguo Zhou & Minshan Chen

Pages: 599-611

Published online: 27 Mar 2018

AbstractforThe mutation of hepatitis B virus and the prognosis of hepatocellular carcinoma after surgery: a pilot study | Full Text | References | PDF (1.1 MB)

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Corrigendum

Correction

Economic burden of the management of metastatic castrate-resistant prostate cancer in Italy: a cost of illness study [Corrigendum]

Page: 613

Published online: 27 Mar 2018

CitationforEconomic burden of the management of metastatic castrate-resistant prostate cancer in Italy: a cost of illness study [Corrigendum] | Full Text | PDF (77.5 KB)

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Review

Review Article

Management of relapsed/refractory marginal zone lymphoma: focus on ibrutinib

Nathan M Denlinger, Narendranath Epperla & Basem M William

Pages: 615-624

Published online: 27 Mar 2018

AbstractforManagement of relapsed/refractory marginal zone lymphoma: focus on ibrutinib | Full Text | References | PDF (212.4 KB)

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Original Research

Article

Prognostic significance of leukopenia during the induction phase in adult B cell acute lymphoblastic leukemia

Chongyun Xing, Bin Liang, Junqing Wu, Qianqian Yang, Gang Hu, Ye Yan, Yu Zhang, Songfu Jiang, Kang Yu & Jianhua Feng

Pages: 625-635

Published online: 28 Mar 2018

AbstractforPrognostic significance of leukopenia during the induction phase in adult B cell acute lymphoblastic leukemia | Full Text | References | PDF (547 KB)

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Article

The association between long-term conditions and uptake of population-based screening for colorectal cancer: results from two English cohort studies

Benjamin Kearns, Jim Chilcott, Clare Relton, Sophie Whyte, Helen Buckley Woods, Claire Nickerson & Amanda Loban

Pages: 637-645

Published online: 28 Mar 2018

AbstractforThe association between long-term conditions and uptake of population-based screening for colorectal cancer: results from two English cohort studies | Full Text | References | PDF (174.1 KB)

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Review

Review Article

Spotlight on dabrafenib/trametinib in the treatment of non-small-cell lung cancer: place in therapy

Thomas C Weart, Kenneth D Miller & Charles B Simone 2nd

Pages: 647-652

Published online: 03 Apr 2018

AbstractforSpotlight on dabrafenib/trametinib in the treatment of non-small-cell lung cancer: place in therapy | Full Text | References | PDF (127.8 KB)

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Original Research

Article

Poorer prognosis in young female patients with non-metastatic colorectal cancer: a hospital-based analysis of 5,047 patients in China

Lijun Shen, Miao Mo, Leon Jia, Huixun Jia, Qingguo Li, Lei Liang, Debing Shi, Zhen Zhang, Sanjun Cai, Xinxiang Li & Ji Zhu

Pages: 653-661

Published online: 04 Apr 2018

AbstractforPoorer prognosis in young female patients with non-metastatic colorectal cancer: a hospital-based analysis of 5,047 patients in China | Full Text | References | PDF (2.5 MB)

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Article

ANLN functions as a key candidate gene in cervical cancer as determined by integrated bioinformatic analysis

Leilei Xia, Xiaoling Su, Jizi Shen, Qi Meng, Jiuqiong Yan, Caihong Zhang, Yu Chen, Han Wang & Mingjuan Xu

Pages: 663-670

Published online: 05 Apr 2018

AbstractforANLN functions as a key candidate gene in cervical cancer as determined by integrated bioinformatic analysis | Full Text | References | PDF (5.2 MB)

107 Views
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Article

The impact of the lymph node density on overall survival in patients with Wilms’ tumor: a SEER analysis

Haisheng You, Jin Yang, Qingqing Liu, Lina Tang, Qingting Bu, Zhenyu Pan & Jun Lyu

Pages: 671-677

Published online: 06 Apr 2018

AbstractforThe impact of the lymph node density on overall survival in patients with Wilms’ tumor: a SEER analysis | Full Text | References | PDF (313.7 KB)

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Article

Marker of proliferation Ki-67 expression is associated with transforming growth factor beta 1 and can predict the prognosis of patients with hepatic B virus-related hepatocellular carcinoma

Chengkun Yang, Hao Su, Xiwen Liao, Chuangye Han, Tingdong Yu, Guangzhi Zhu, Xiangkun Wang, Cheryl Ann Winkler, Stephen J O’Brien & Tao Peng

Pages: 679-696

Published online: 10 Apr 2018

AbstractforMarker of proliferation Ki-67 expression is associated with transforming growth factor beta 1 and can predict the prognosis of patients with hepatic B virus-related hepatocellular carcinoma | Full Text | References | PDF (9.5 MB)

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Article

The association of polymorphisms in miRNAs with nonsmall cell lung cancer in a Han Chinese population

Chuanyin Li, Yu Zhang, Yingfu Li, Qianli Ma, Shuyuan Liu, Yueting Yao, Fang Tan, Li Shi & Yufeng Yao

Pages: 697-704

Published online: 10 Apr 2018

AbstractforThe association of polymorphisms in miRNAs with nonsmall cell lung cancer in a Han Chinese population | Full Text | References | PDF (163.8 KB)

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Article

Robotic versus laparoscopic gastrectomy with D2 lymph node dissection for advanced gastric cancer: a propensity score-matched analysis

Zhengyan Li, Jipeng Li, Bofei Li, Bin Bai, Yezhou Liu, Bo Lian & Qingchuan Zhao

Pages: 705-714

Published online: 10 Apr 2018

AbstractforRobotic versus laparoscopic gastrectomy with D2 lymph node dissection for advanced gastric cancer: a propensity score-matched analysis | Full Text | References | PDF (715.5 KB)

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Review

Review Article

Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation

Wei Guo, Hor Yue Tan, Ning Wang, Xuanbin Wang & Yibin Feng

Pages: 715-734

Published online: 11 Apr 2018

AbstractforDeciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation | Full Text | References | PDF (917.6 KB)

162 Views
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Review Article

Management of hemorrhage in gastrointestinal stromal tumors: a review

Qi Liu, Fanmin Kong, Jianping Zhou, Ming Dong & Qi Dong

Pages: 735-743

Published online: 12 Apr 2018

AbstractforManagement of hemorrhage in gastrointestinal stromal tumors: a review | Full Text | References | PDF (1.4 MB)

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Methodology

Article

The role of the pathology department in the preanalytical phase of molecular analyses

Sergiu Susman, Ioana Berindan-Neagoe, Bobe Petrushev, Radu Pirlog, Ioan-Stefan Florian, Carmen-Mihaela Mihu, Cristian Berce, Lucian Craciun, Ravnit Grewal & Ciprian Tomuleasa

Pages: 745-753

Published online: 12 Apr 2018

AbstractforThe role of the pathology department in the preanalytical phase of molecular analyses | Full Text | References | PDF (1.9 MB)

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Original Research

Article

Quantitative assessment of the clinical susceptibility of calcium-sensing receptor polymorphisms in cancer patients

Haohai Huang, Tao Li, Dan Liao, Zhu Zhu & Yong Dong

Pages: 755-763

Published online: 12 Apr 2018

AbstractforQuantitative assessment of the clinical susceptibility of calcium-sensing receptor polymorphisms in cancer patients | Full Text | References | PDF (413.1 KB)

47 Views
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Article

Genetic variants in the nucleotide excision repair pathway genes and gastric cancer susceptibility in a southern Chinese population

Jing He, Zhen-Jian Zhuo, Anqi Zhang, Jinhong Zhu, Rui-Xi Hua, Wen-Qiong Xue, Shao-Dan Zhang, Jiang-Bo Zhang, Xi-Zhao Li & Wei-Hua Jia

Pages: 765-774

Published online: 12 Apr 2018

AbstractforGenetic variants in the nucleotide excision repair pathway genes and gastric cancer susceptibility in a southern Chinese population | Full Text | References | PDF (177.8 KB)

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Article

MicroRNA-142-3p is involved in regulation of MGMT expression in glioblastoma cells

Yi-Yen Lee, Aliaksandr A Yarmishyn, Mong-Lien Wang, Hsiao-Yun Chen, Shih-Hwa Chiou, Yi-Ping Yang, Chun-Fu Lin, Pin-I Huang, Yi-Wei Chen, Hsin-I Ma & Ming-Teh Chen

Pages: 775-785

Published online: 12 Apr 2018

AbstractforMicroRNA-142-3p is involved in regulation of MGMT expression in glioblastoma cells | Full Text | References | PDF (1.5 MB)

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Article

Identification of potential prognostic microRNA biomarkers for predicting survival in patients with hepatocellular carcinoma

Xiwen Liao, Guangzhi Zhu, Rui Huang, Chengkun Yang, Xiangkun Wang, Ketuan Huang, Tingdong Yu, Chuangye Han, Hao Su & Tao Peng

Pages: 787-803

Published online: 13 Apr 2018

AbstractforIdentification of potential prognostic microRNA biomarkers for predicting survival in patients with hepatocellular carcinoma | Full Text | References | PDF (7.4 MB)

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Article

Effective prevention of sorafenib-induced hand–foot syndrome by dried-bonito broth

Kenya Kamimura, Yoko Shinagawa-Kobayashi, Ryo Goto, Kohei Ogawa, Takeshi Yokoo, Akira Sakamaki, Satoshi Abe, Hiroteru Kamimura, Takeshi Suda, Hiroshi Baba, Takayuki Tanaka, Yoshizu Nozawa, Naoto Koyama, Masaaki Takamura, Hirokazu Kawai, Satoshi Yamagiwa, Yutaka Aoyagi & Shuji Terai

Pages: 805-813

Published online: 17 Apr 2018

AbstractforEffective prevention of sorafenib-induced hand–foot syndrome by dried-bonito broth | Full Text | References | PDF (1.4 MB)

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Article

Prognostic significance of preoperative serum albumin in epithelial ovarian cancer patients: a systematic review and dose–response meta-analysis of observational studies

Li-Na Ge & Feng Wang

Pages: 815-825

Published online: 17 Apr 2018

AbstractforPrognostic significance of preoperative serum albumin in epithelial ovarian cancer patients: a systematic review and dose–response meta-analysis of observational studies | Full Text | References | PDF (1.4 MB)

81 Views
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Article

Emergency treatment of complicated colorectal cancer

Giovanni Domenico Tebala, Andrea Natili, Antonio Gallucci, Gioia Brachini, Abdul Qayyum Khan, Domenico Tebala & Andrea Mingoli

Pages: 827-838

Published online: 20 Apr 2018

AbstractforEmergency treatment of complicated colorectal cancer | Full Text | References | PDF (188.5 KB)

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Review

Review Article

Transoral robotic surgery for oropharyngeal cancer: patient selection and special considerations

R Michael Baskin, Brian J Boyce, Robert Amdur, William M Mendenhall, Kathryn Hitchcock, Natalie Silver & Peter T Dziegielewski

Pages: 839-846

Published online: 20 Apr 2018

AbstractforTransoral robotic surgery for oropharyngeal cancer: patient selection and special considerations | Full Text | References | PDF (247.1 KB)

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Original Research

Article

A novel nomogram for the prediction of intrahepatic cholangiocarcinoma in patients with intrahepatic lithiasis complicated by imagiologically diagnosed mass

Gang Chen, Huajun Yu, Yi Wang, Chenhao Li, Mengtao Zhou, Zhengping Yu, Xiangwu Zheng, Xiuling Wu, Yunfeng Shan, Qiyu Zhang & Qiqiang Zeng

Pages: 847-856

Published online: 23 Apr 2018

AbstractforA novel nomogram for the prediction of intrahepatic cholangiocarcinoma in patients with intrahepatic lithiasis complicated by imagiologically diagnosed mass | Full Text | References | PDF (1.6 MB)

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Article

Elevated circulating miR-182 acts as a diagnostic biomarker for early colorectal cancer

Xiangxiang Liu, Tao Xu, Xiuxiu Hu, XiaoXiang Chen, Kaixuan Zeng, Li Sun & Shukui Wang

Pages: 857-865

Published online: 24 Apr 2018

AbstractforElevated circulating miR-182 acts as a diagnostic biomarker for early colorectal cancer | Full Text | References | PDF (1.4 MB)

89 Views
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Article

Association of two FOXP3 polymorphisms with breast cancer susceptibility in Chinese Han women

Tian Tian, Meng Wang, Yi Zheng, Tielin Yang, Wenge Zhu, Hongtao Li, Shuai Lin, Kang Liu, Peng Xu, Yujiao Deng, Linghui Zhou & Zhijun Dai

Pages: 867-872

Published online: 26 Apr 2018

AbstractforAssociation of two FOXP3 polymorphisms with breast cancer susceptibility in Chinese Han women | Full Text | References | PDF (179.8 KB)

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Article

Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma

Li-Hua Yang, Ye Wang, Shi Qiao, Min-Jun Wang, Fei Chen, Xiao-Yuan Zi, Jian-Xiu Li, Hai-Bin Zhang, Bing Yu & Yi-Ping Hu

Pages: 873-885

Published online: 26 Apr 2018

AbstractforLiver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma | Full Text | References | PDF (10.5 MB)

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Article

Paeoniflorin inhibits glioblastoma growth in vivo and in vitro: a role for the Triad3A-dependent ubiquitin proteasome pathway in TLR4 degradation

Zhaotao Wang, Guoyong Yu, Zhi Liu, Jianwei Zhu, Chen Chen, Ru-en Liu & Ruxiang Xu

Pages: 887-897

Published online: 27 Apr 2018

AbstractforPaeoniflorin inhibits glioblastoma growth in vivo and in vitro: a role for the Triad3A-dependent ubiquitin proteasome pathway in TLR4 degradation | Full Text | References | PDF (3.1 MB)

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Article

A favorable tumor size to define papillary thyroid microcarcinoma: an analysis of 1176 consecutive cases

Yanping Gong, Genpeng Li, Jianyong Lei, Jiaying You, Ke Jiang, Zhihui Li, Rixiang Gong & Jingqiang Zhu

Pages: 899-906

Published online: 27 Apr 2018

AbstractforA favorable tumor size to define papillary thyroid microcarcinoma: an analysis of 1176 consecutive cases | Full Text | References | PDF (928.3 KB)

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Article

Prognostic value of microRNAs in colorectal cancer: a meta-analysis

Song Gao, Zhi-Ying Zhao, Rong Wu, Yue Zhang & Zhen-Yong Zhang

Pages: 907-929

Published online: 30 Apr 2018

AbstractforPrognostic value of microRNAs in colorectal cancer: a meta-analysis | Full Text | References | PDF (3 MB)

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Review

Review Article

Durvalumab: a potential maintenance therapy in surgery-ineligible non-small-cell lung cancer

Michael R Shafique, Lary A Robinson & Scott Antonia

Pages: 931-940

Published online: 01 May 2018

AbstractforDurvalumab: a potential maintenance therapy in surgery-ineligible non-small-cell lung cancer | Full Text | References | PDF (171.4 KB)

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Original Research

Article

Highly elevated soluble Tim-3 levels correlate with increased hepatocellular carcinoma risk and poor survival of hepatocellular carcinoma patients in chronic hepatitis B virus infection

Fang Li, Na Li, Jiao Sang, Xiude Fan, Huan Deng, Xiaoge Zhang, Qunying Han, Yi Lv & Zhengwen Liu

Pages: 941-951

Published online: 01 May 2018

AbstractforHighly elevated soluble Tim-3 levels correlate with increased hepatocellular carcinoma risk and poor survival of hepatocellular carcinoma patients in chronic hepatitis B virus infection | Full Text | References | PDF (722.4 KB)

84 Views
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Article

Genome-wide association pathway analysis to identify candidate single nucleotide polymorphisms and molecular pathways associated with TP53 expression status in HBV-related hepatocellular carcinoma

Xiwen Liao, Long Yu, Xiaoguang Liu, Chuangye Han, Tingdong Yu, Wei Qin, Chengkun Yang, Guangzhi Zhu, Hao Su & Tao Peng

Pages: 953-967

Published online: 01 May 2018

AbstractforGenome-wide association pathway analysis to identify candidate single nucleotide polymorphisms and molecular pathways associated with TP53 expression status in HBV-related hepatocellular carcinoma | Full Text | References | PDF (5.3 MB)

63 Views
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Article

ITGA7 functions as a tumor suppressor and regulates migration and invasion in breast cancer

Adheesh Bhandari, Erjie Xia, Yuying Zhou, Yaoyao Guan, Jingjing Xiang, Lingguo Kong, Yinghao Wang, Fan Yang, Ouchen Wang & Xiaohua Zhang

Pages: 969-976

Published online: 01 May 2018

AbstractforITGA7 functions as a tumor suppressor and regulates migration and invasion in breast cancer | Full Text | References | PDF (4 MB)

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Article

Preoperative neutrophil-to-lymphocyte ratio as a prognostic predictor after curative-intent surgery for hepatocellular carcinoma: experience from a developing country

Danijel Galun, Aleksandar Bogdanovic, Jelena Djokic Kovac, Predrag Bulajic, Zlatibor Loncar & Marinko Zuvela

Pages: 977-988

Published online: 04 May 2018

AbstractforPreoperative neutrophil-to-lymphocyte ratio as a prognostic predictor after curative-intent surgery for hepatocellular carcinoma: experience from a developing country | Full Text | References | PDF (888.5 KB)

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Article

MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells

Li Chai, Xiao-Jing Kang, Zhen-Zhu Sun, Ming-Feng Zeng, Shi-Rong Yu, Yuan Ding, Jun-Qin Liang, Ting-Ting Li & Juan Zhao

Pages: 989-1003

Published online: 03 May 2018

AbstractforMiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells | Full Text | References | PDF (8.8 MB)

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Article

Co-existence of BRAF^V600E and TERT promoter mutations in papillary thyroid carcinoma is associated with tumor aggressiveness, but not with lymph node metastasis

Haoyu Ren, Yifan Shen, Daixing Hu, Wei He, Jing Zhou, Yijia Cao, Yu Mao, Yi Dou, Wei Xiong, Qi Xiao, Yuhong Zhang & Xinliang Su

Pages: 1005-1013

Published online: 03 May 2018

AbstractforCo-existence of BRAF^V600E and TERT promoter mutations in papillary thyroid carcinoma is associated with tumor aggressiveness, but not with lymph node metastasis | Full Text | References | PDF (1.6 MB)

76 Views
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Article

Is progression-free survival a more relevant endpoint than overall survival in first-line HR+/HER2− metastatic breast cancer?

Anna Forsythe, David Chandiwana, Janina Barth, Marroon Thabane, Johan Baeck, Anastasiya Shor & Gabriel Tremblay

Pages: 1015-1025

Published online: 04 May 2018

AbstractforIs progression-free survival a more relevant endpoint than overall survival in first-line HR+/HER2− metastatic breast cancer? | Full Text | References | PDF (755.1 KB)

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Article

Genetic variants in the exon region of versican predict survival of patients with resected early-stage hepatitis B virus-associated hepatocellular carcinoma

Xiaoguang Liu, Chuangye Han, Xiwen Liao, Long Yu, Guangzhi Zhu, Hao Su, Wei Qin, Sicong Lu, Xinping Ye & Tao Peng

Pages: 1027-1036

Published online: 04 May 2018

AbstractforGenetic variants in the exon region of versican predict survival of patients with resected early-stage hepatitis B virus-associated hepatocellular carcinoma | Full Text | References | PDF (891.8 KB)

52 Views
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Article

Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population

Xinping Ye, Xiangkun Wang, Liming Shang, Guangzhi Zhu, Hao Su, Chuangye Han, Wei Qin, Guanghui Li & Tao Peng

Pages: 1037-1050

Published online: 04 May 2018

AbstractforGenetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population | Full Text | References | PDF (2.8 MB)

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Article

Triple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape

Christian Garbar, Corinne Mascaux, Yacine Merrouche & Armand Bensussan

Pages: 1051-1059

Published online: 04 May 2018

AbstractforTriple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape | Full Text | References | PDF (3.3 MB)

76 Views
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Article

Survival outcomes of radical prostatectomy and external beam radiotherapy in clinically localized high-risk prostate cancer: a population-based, propensity score matched study

Xiaobin Gu, Xianshu Gao, Ming Cui, Mu Xie, Mingwei Ma, Shangbin Qin, Xiaoying Li, Xin Qi, Yun Bai & Dian Wang

Pages: 1061-1067

Published online: 08 May 2018

AbstractforSurvival outcomes of radical prostatectomy and external beam radiotherapy in clinically localized high-risk prostate cancer: a population-based, propensity score matched study | Full Text | References | PDF (962.2 KB)

64 Views
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Article

Orbital solitary fibrous tumor: a clinicopathologic study from a Chinese tertiary hospital with a literature review

Jianqin Shen, Huiyan Li, Shi Feng & Hongguang Cui

Pages: 1069-1078

Published online: 09 May 2018

AbstractforOrbital solitary fibrous tumor: a clinicopathologic study from a Chinese tertiary hospital with a literature review | Full Text | References | PDF (3.3 MB)

61 Views
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Article

Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway

Mohammad Hassan Hodroj, Achraf Jardaly, Sarah Abi Raad, Annalise Zouein & Sandra Rizk

Pages: 1079-1088

Published online: 10 May 2018

AbstractforAndrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway | Full Text | References | PDF (3.6 MB)

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Review

Review Article

A review of soft-tissue sarcomas: translation of biological advances into treatment measures

Ngoc T Hoang, Luis A Acevedo, Michael J Mann & Bhairavi Tolani

Pages: 1089-1114

Published online: 10 May 2018

AbstractforA review of soft-tissue sarcomas: translation of biological advances into treatment measures | Full Text | References | PDF (753.9 KB)

307 Views
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Original Research

Article

Blockage of store-operated Ca²⁺ entry antagonizes Epstein–Barr virus-promoted angiogenesis by inhibiting Ca²⁺ signaling-regulated VEGF production in nasopharyngeal carcinoma

Jiaxiang Ye, Junqi Huang, Qian He, Weilin Zhao, Xiaoying Zhou, Zhe Zhang, Yongqiang Li, Jiazhang Wei & Jinyan Zhang

Pages: 1115-1124

Published online: 10 May 2018

AbstractforBlockage of store-operated Ca²⁺ entry antagonizes Epstein–Barr virus-promoted angiogenesis by inhibiting Ca²⁺ signaling-regulated VEGF production in nasopharyngeal carcinoma | Full Text | References | PDF (4.4 MB)

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Article

Do additional cores from cancer-suspicious lesions on transrectal ultrasound improve prostate cancer detection including index tumors over 12-core systematic biopsy?

Jung Ki Jo, Sung Kyu Hong, Seok-Soo Byun, Sang Eun Lee & Seong Jin Jeong

Pages: 1125-1131

Published online: 10 May 2018

AbstractforDo additional cores from cancer-suspicious lesions on transrectal ultrasound improve prostate cancer detection including index tumors over 12-core systematic biopsy? | Full Text | References | PDF (790.9 KB)

52 Views
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Article

Decreased survival in patients with carcinoma of axillary tail versus upper outer quadrant breast cancers: a SEER population-based study

Zong-Chao Gou, Xi-Yu Liu, Yi Xiao, Shen Zhao, Yi-Zhou Jiang & Zhi-Ming Shao

Pages: 1133-1141

Published online: 14 May 2018

AbstractforDecreased survival in patients with carcinoma of axillary tail versus upper outer quadrant breast cancers: a SEER population-based study | Full Text | References | PDF (772.4 KB)

98 Views
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Article

MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project

Elena Tagliabue, Sara Gandini, Rino Bellocco, Patrick Maisonneuve, Julia Newton-Bishop, David Polsky, DeAnn Lazovich, Peter A Kanetsky, Paola Ghiorzo, Nelleke A Gruis, Maria Teresa Landi, Chiara Menin, Maria Concetta Fargnoli, Jose Carlos García-Borrón, Jiali Han, Julian Little, Francesco Sera, Sara Raimondi & On behalf of the M-SKIP Study Group

Pages: 1143-1154

Published online: 14 May 2018

AbstractforMC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project | Full Text | References | PDF (742.4 KB)

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Article

The lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer

Chang Zheng, Xuelian Li, Biyun Qian, Nannan Feng, Sumeng Gao, Yuxia Zhao & Baosen Zhou

Pages: 1155-1162

Published online: 14 May 2018

AbstractforThe lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer | Full Text | References | PDF (3.2 MB)

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Article

RETRACTED ARTICLE: Overexpression of chloride channel-3 predicts unfavorable prognosis and promotes cellular invasion in gastric cancer

Jianjun Peng, Wei Chen, Jianhui Chen, Yujie Yuan, Jian Zhang & Yulong He

Pages: 1163-1175

Published online: 14 May 2018

AbstractforRETRACTED ARTICLE: Overexpression of chloride channel-3 predicts unfavorable prognosis and promotes cellular invasion in gastric cancer | PDF (5.6 MB)

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Article

Preoperative serum apolipoprotein A-I levels predict long-term survival in non-muscle-invasive bladder cancer patients

Zhenhua Shang, Jukun Wang, Xu Wang, Hao Yan, Bo Cui, Chunsong Jia, Qi Wang, Xin Cui, Jin Li & Tongwen Ou

Pages: 1177-1190

Published online: 14 May 2018

AbstractforPreoperative serum apolipoprotein A-I levels predict long-term survival in non-muscle-invasive bladder cancer patients | Full Text | References | PDF (1.2 MB)

64 Views
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Article

Prognostic factors for survival among patients with primary bone sarcomas of small bones

Zhan Wang, Shu Li, Yong Li, Nong Lin, Xin Huang, Meng Liu, Weibo Pan, Xiaobo Yan, Lingling Sun, Hengyuan Li, Binghao Li, Hao Qu, Yan Wu, Peng Lin & Zhaoming Ye

Pages: 1191-1199

Published online: 14 May 2018

AbstractforPrognostic factors for survival among patients with primary bone sarcomas of small bones | Full Text | References | PDF (1.1 MB)

57 Views
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Article

Incidental thyroid carcinoma in surgery-treated hyperthyroid patients with Graves’ disease: a systematic review and meta-analysis of cohort studies

Qingyi Jia, Xiaodan Li, Ying Liu, Ling Li, Joey SW Kwong, Kaiyun Ren, Yong Jiang, Xin Sun, Haoming Tian & Sheyu Li

Pages: 1201-1207

Published online: 21 May 2018

AbstractforIncidental thyroid carcinoma in surgery-treated hyperthyroid patients with Graves’ disease: a systematic review and meta-analysis of cohort studies | Full Text | References | PDF (494.1 KB)

67 Views
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Article

Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA

Rui Zhang, Bojiang Chen, Xiang Tong, Ye Wang, Chengdi Wang, Jing Jin, Panwen Tian & Weimin Li

Pages: 1209-1218

Published online: 16 May 2018

AbstractforDiagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA | Full Text | References | PDF (964.4 KB)

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Review

Review Article

Role of Lactobacillus in cervical cancer

Xi Yang, Miao Da, Wenyuan Zhang, Quan Qi, Chun Zhang & Shuwen Han

Pages: 1219-1229

Published online: 16 May 2018

AbstractforRole of Lactobacillus in cervical cancer | Full Text | References | PDF (925.1 KB)

602 Views
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Original Research

Article

Dichloroacetate enhances the antitumor efficacy of chemotherapeutic agents via inhibiting autophagy in non-small-cell lung cancer

Xiao Lu, Dong Zhou, Bing Hou, Quan-Xing Liu, Qian Chen, Xu-Feng Deng, Zu-Bin Yu, Ji-Gang Dai & Hong Zheng

Pages: 1231-1241

Published online: 16 May 2018

AbstractforDichloroacetate enhances the antitumor efficacy of chemotherapeutic agents via inhibiting autophagy in non-small-cell lung cancer | Full Text | References | PDF (4.7 MB)

82 Views
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Article

Expression and significance of RRBP1 in esophageal carcinoma

Liang Wang, Ming Wang, Mingyun Zhang, Xingde Li, Zhongcheng Zhu & Haiyan Wang

Pages: 1243-1249

Published online: 17 May 2018

AbstractforExpression and significance of RRBP1 in esophageal carcinoma | Full Text | References | PDF (1.7 MB)

66 Views
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Article

The location, histologic type, and stage of lung cancer are associated with bleeding during endobronchial biopsy

Saibin Wang, Qian Ye, Junwei Tu & Yong Song

Pages: 1251-1257

Published online: 17 May 2018

AbstractforThe location, histologic type, and stage of lung cancer are associated with bleeding during endobronchial biopsy | Full Text | References | PDF (356.4 KB)

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Review

Review Article

Severe cutaneous adverse reactions induced by targeted anticancer therapies and immunotherapies

Chun-Bing Chen, Ming-Ying Wu, Chau Yee Ng, Chun-Wei Lu, Jennifer Wu, Pei-Han Kao, Chan-Keng Yang, Meng-Ting Peng, Chen-Yang Huang, Wen-Cheng Chang, Rosaline Chung-Yee Hui, Chih-Hsun Yang, Shun-Fa Yang, Wen-Hung Chung & Shih-Chi Su

Pages: 1259-1273

Published online: 17 May 2018

AbstractforSevere cutaneous adverse reactions induced by targeted anticancer therapies and immunotherapies | Full Text | References | PDF (3 MB)

193 Views
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Original Research

Article

Screening differential circular RNA expression profiles reveal that hsa_circ_0128298 is a biomarker in the diagnosis and prognosis of hepatocellular carcinoma

Dawei Chen, Chenyue Zhang, Jiamao Lin, Xinyu Song & Haiyong Wang

Pages: 1275-1283

Published online: 18 May 2018

AbstractforScreening differential circular RNA expression profiles reveal that hsa_circ_0128298 is a biomarker in the diagnosis and prognosis of hepatocellular carcinoma | Full Text | References | PDF (1.7 MB)

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Article

Associated factors for oral health problems in a sample of Saudi cancer patients

Nagarajkumar Yenugadhati, Alhanouf Naji Albalawi, Aisha Taha Qureshey, Eiman Taha Qureshey, Hamdan Al-Jahdali, Abdul Rahman Jazieh & Anwar E Ahmed

Pages: 1285-1293

Published online: 21 May 2018

AbstractforAssociated factors for oral health problems in a sample of Saudi cancer patients | Full Text | References | PDF (342.2 KB)

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Article

Stereotactic body radiation therapy plus induction or adjuvant chemotherapy for early stage but medically inoperable pancreatic cancer: A propensity score-matched analysis of a prospectively collected database

Xiaofei Zhu, Fuqi Li, Wenyu Liu, Dongchen Shi, Xiaoping Ju, Yangsen Cao, Yuxin Shen, Fei Cao, Shuiwang Qing, Fang Fang, Zhen Jia & Huojun Zhang

Pages: 1295-1304

Published online: 21 May 2018

AbstractforStereotactic body radiation therapy plus induction or adjuvant chemotherapy for early stage but medically inoperable pancreatic cancer: A propensity score-matched analysis of a prospectively collected database | Full Text | References | PDF (481.3 KB)

71 Views
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Article

Association of FGFR2 and PI3KCA genetic variants with the risk of breast cancer in a Chinese population

Yang Wang, Haiyu Zhang, Mingzhen Lin & Yongsheng Wang

Pages: 1305-1311

Published online: 21 May 2018

AbstractforAssociation of FGFR2 and PI3KCA genetic variants with the risk of breast cancer in a Chinese population | Full Text | References | PDF (383.9 KB)

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Article

Clinical analysis of four serum tumor markers in 458 patients with ovarian tumors: diagnostic value of the combined use of HE4, CA125, CA19-9, and CEA in ovarian tumors

Fawen Chen, Jing Shen, Jianwei Wang, Pengwei Cai & Yi Huang

Pages: 1313-1318

Published online: 22 May 2018

AbstractforClinical analysis of four serum tumor markers in 458 patients with ovarian tumors: diagnostic value of the combined use of HE4, CA125, CA19-9, and CEA in ovarian tumors | Full Text | References | PDF (384.8 KB)

132 Views
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Article

Matching-adjusted indirect treatment comparison of ribociclib and palbociclib in HR+, HER2− advanced breast cancer

Gabriel Tremblay, David Chandiwana, Mike Dolph, Jaclyn Hearnden, Anna Forsythe & Mauricio Monaco

Pages: 1319-1327

Published online: 22 May 2018

AbstractforMatching-adjusted indirect treatment comparison of ribociclib and palbociclib in HR+, HER2− advanced breast cancer | Full Text | References | PDF (311.1 KB)

139 Views
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Article

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

Liyi Xie, Chen Lin, Qingfu Zhang, Hailan Piao, Darell D Bigner, Zhen Zhang & Xuhui Bao

Pages: 1329-1340

Published online: 24 May 2018

AbstractforElevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer | Full Text | References | PDF (2.5 MB)

61 Views
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Article

Association of mRNA expression of TP53 and the TP53 codon 72 Arg/Pro gene polymorphism with colorectal cancer risk in Asian population: a bioinformatics analysis and meta-analysis

Zhiyong Dong, Longzhi Zheng, Weimin Liu & Cunchuan Wang

Pages: 1341-1349

Published online: 25 May 2018

AbstractforAssociation of mRNA expression of TP53 and the TP53 codon 72 Arg/Pro gene polymorphism with colorectal cancer risk in Asian population: a bioinformatics analysis and meta-analysis | Full Text | References | PDF (2.1 MB)

65 Views
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Article

Clinical effect of MUC1 and its relevance to BRAF V600E mutation in papillary thyroid carcinoma: a case–control study

Quan Li, Wen-Xu Jin, Yi-Xiang Jin, Zhou-Ci Zheng, Xiao-Fen Zhou, Qing-Xuan Wang, Dan-Rong Ye, Yi-Han Sun, Xiao-Hua Zhang, Ou-Chen Wang, En-Dong Chen & Ye-Feng Cai

Pages: 1351-1358

Published online: 29 May 2018

AbstractforClinical effect of MUC1 and its relevance to BRAF V600E mutation in papillary thyroid carcinoma: a case–control study | Full Text | References | PDF (187.8 KB)

56 Views
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Article

Age distribution and age-related outcomes of olfactory neuroblastoma: a population-based analysis

Zhenzhen Yin, Youyou Wang, Yuemei Wu, Ximei Zhang, Fengming Wang, Peiguo Wang, Zhen Tao & Zhiyong Yuan

Pages: 1359-1364

Published online: 29 May 2018

AbstractforAge distribution and age-related outcomes of olfactory neuroblastoma: a population-based analysis | Full Text | References | PDF (411.2 KB)

68 Views
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Article

Tumor-infiltrating lymphocyte as a prognostic biomarker in stage IV colorectal cancer should take into account the metastatic status and operation modality

Qian-Kun Xie, Wen-Zhuo He, Wan-Ming Hu, Lin Yang, Chang Jiang, Peng-Fei Kong, Yuan-Zhong Yang, Qiong Yang, Hui-Zhong Zhang, Bei Zhang & Liang-Ping Xia

Pages: 1365-1375

Published online: 30 May 2018

AbstractforTumor-infiltrating lymphocyte as a prognostic biomarker in stage IV colorectal cancer should take into account the metastatic status and operation modality | Full Text | References | PDF (2.2 MB)

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Article

Polymorphism in lncRNA AC008392.1 and its interaction with smoking on the risk of lung cancer in a Chinese population

Xiaoting Lv, Zhigang Cui, Hang Li, Juan Li, Zitai Yang, Yanhong Bi, Min Gao, Baosen Zhou & Zhihua Yin

Pages: 1377-1387

Published online: 30 May 2018

AbstractforPolymorphism in lncRNA AC008392.1 and its interaction with smoking on the risk of lung cancer in a Chinese population | Full Text | References | PDF (216 KB)

42 Views
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Article

Performance status dynamics during treatment with nab-paclitaxel plus gemcitabine versus gemcitabine alone for metastatic pancreatic cancer

E Gabriela Chiorean, Daniel Von Hoff, Yin Wan, Sandra Margunato-Debay, Marc Botteman & David Goldstein

Pages: 1389-1396

Published online: 31 May 2018

AbstractforPerformance status dynamics during treatment with nab-paclitaxel plus gemcitabine versus gemcitabine alone for metastatic pancreatic cancer | Full Text | References | PDF (404.8 KB)

51 Views
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Article

Combined microwave ablation and minimally invasive open decompression for the management of thoracic metastasis in breast cancer

Bin Liu, Zhenchao Yuan & Chang Yuan Wei

Pages: 1397-1401

Published online: 31 May 2018

AbstractforCombined microwave ablation and minimally invasive open decompression for the management of thoracic metastasis in breast cancer | Full Text | References | PDF (1 MB)

64 Views
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Article

Prognostic value and clinical significance of long noncoding RNA CASC2 in human malignancies: a meta-analysis

Juan Cai, Xueliang Zuo, Zhiqiang Chen, Wenying Zhao, Yiping Zhu, Zhengxiang Zhang & Xiaobing Ye

Pages: 1403-1412

Published online: 31 May 2018

AbstractforPrognostic value and clinical significance of long noncoding RNA CASC2 in human malignancies: a meta-analysis | Full Text | References | PDF (1 MB)

54 Views
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Article

Cystectomy for bladder cancer in elderly patients is not associated with increased 30- and 90-day mortality or readmission, length of stay, and cost: propensity score matching using a population database

Wei-Yu Lin, Chun-Te Wu, Miao-Fen Chen, Ying-Hsu Chang, Cheng-Li Lin & Chia-Hung Kao

Pages: 1413-1418

Published online: 31 May 2018

AbstractforCystectomy for bladder cancer in elderly patients is not associated with increased 30- and 90-day mortality or readmission, length of stay, and cost: propensity score matching using a population database | Full Text | References | PDF (248.3 KB)

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Article

Concurrent chemoradiotherapy versus radiotherapy alone for locoregionally advanced nasopharyngeal carcinoma in the era of intensity-modulated radiotherapy: a meta-analysis

Yan He, Tao Guo, Hui Guan, Jingjing Wang, Yu Sun & Xingchen Peng

Pages: 1419-1428

Published online: 06 Jun 2018

AbstractforConcurrent chemoradiotherapy versus radiotherapy alone for locoregionally advanced nasopharyngeal carcinoma in the era of intensity-modulated radiotherapy: a meta-analysis | Full Text | References | PDF (1.3 MB)

85 Views
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Article

Influence of TS (rs34743033) and RUNX1 (rs2014300) gene polymorphisms on survival outcomes of fluorouracil-based chemotherapy in Chinese advanced gastric cancer patients

Rongbo Han, Jingsun Wei, Honghong Zhang, Xinyu Su, Xia Chu, Yuetong Chen, Yang Gong, Xiujuan Wang, Junfeng Shi & Jinfei Chen

Pages: 1429-1437

Published online: 06 Jun 2018

AbstractforInfluence of TS (rs34743033) and RUNX1 (rs2014300) gene polymorphisms on survival outcomes of fluorouracil-based chemotherapy in Chinese advanced gastric cancer patients | Full Text | References | PDF (729.5 KB)

53 Views
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Article

Notch signaling pathway mediates Doxorubicin-driven apoptosis in cancers

Zixin Huang, Shuibin Lin, Chongde Long, Xin Zhou, Yuting Fan, Xielan Kuang, Jia He, Jie Ning, Han Zhang, Qingjiong Zhang & Huangxuan Shen

Pages: 1439-1448

Published online: 08 Jun 2018

AbstractforNotch signaling pathway mediates Doxorubicin-driven apoptosis in cancers | Full Text | References | PDF (4.5 MB)

79 Views
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Article

LncRNAs and EGFRvIII sequestered in TEPs enable blood-based NSCLC diagnosis

Chang-Liang Luo, Zhi-Gao Xu, Hao Chen, Jia Ji, Yu-Hui Wang, Wei Hu, Kun Wang, Wu-Wen Zhang, Chun-Hui Yuan & Fu-Bing Wang

Pages: 1449-1459

Published online: 08 Jun 2018

AbstractforLncRNAs and EGFRvIII sequestered in TEPs enable blood-based NSCLC diagnosis | Full Text | References | PDF (3.1 MB)

78 Views
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Case Report

Extramedullary hematopoiesis secondary to malignant solid tumors: a case report and literature review

Youting Bao, Zhichao Liu, Meiying Guo, Butuo Li, Xindong Sun & Linlin Wang

Pages: 1461-1470

Published online: 08 Jun 2018

AbstractforExtramedullary hematopoiesis secondary to malignant solid tumors: a case report and literature review | Full Text | References | PDF (5.8 MB)

178 Views
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Original Research

Article

Poor prognosis and SATB1 overexpression in solid tumors: a meta-analysis

Shengjie Wang, Junjie Zeng, Rui Xiao, Guoxing Xu, Gang Liu, Disheng Xiong, Yongzhi Ye, Borong Chen, Haibin Wang, Qi Luo & Zhengjie Huang

Pages: 1471-1478

Published online: 08 Jun 2018

AbstractforPoor prognosis and SATB1 overexpression in solid tumors: a meta-analysis | Full Text | References | PDF (832.3 KB)

56 Views
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Article

Expression and clinical significance of autophagic protein LC3B and EMT markers in gastric cancer

Juan-Yi Wang, Tao Wu, Wu Ma, Shuo Li, Wen-Jiang Jing, Jun Ma, Dong-Mei Chen, Xiao-Jie Guo & Ke-Jun Nan

Pages: 1479-1486

Published online: 11 Jun 2018

AbstractforExpression and clinical significance of autophagic protein LC3B and EMT markers in gastric cancer | Full Text | References | PDF (2.3 MB)

85 Views
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Article

Genetic polymorphisms in the TERT gene and susceptibility to non-small cell lung cancer in a Chinese Han population

Chuanyin Li, Xiaona Wang, Yingfu Li, Xinwen Zhang, Mingbo Sun, Shuyuan Liu, Le Sun, Li Shi & Yufeng Yao

Pages: 1487-1495

Published online: 11 Jun 2018

AbstractforGenetic polymorphisms in the TERT gene and susceptibility to non-small cell lung cancer in a Chinese Han population | Full Text | References | PDF (190.4 KB)

61 Views
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Article

Role of palliative radiotherapy in unresectable intrahepatic cholangiocarcinoma: population-based analysis with propensity score matching

Feng Shao, Wei Qi, Fu Tao Meng, Lujun Qiu & Qiang Huang

Pages: 1497-1506

Published online: 13 Jun 2018

AbstractforRole of palliative radiotherapy in unresectable intrahepatic cholangiocarcinoma: population-based analysis with propensity score matching | Full Text | References | PDF (1,003 KB)

71 Views
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Article

A two-microRNA signature as a diagnostic and prognostic marker of pancreatic adenocarcinoma

Yang Yu, Xiao Feng & Shundong Cang

Pages: 1507-1515

Published online: 13 Jun 2018

AbstractforA two-microRNA signature as a diagnostic and prognostic marker of pancreatic adenocarcinoma | Full Text | References | PDF (1.7 MB)

58 Views
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Review

Review Article

Fertility preservation in Hodgkin’s lymphoma patients that undergo targeted molecular therapies: an important step forward from the chemotherapy era

Alexandra Traila, Delia Dima, Patriciu Achimas-Cadariu & Romeo Micu

Pages: 1517-1526

Published online: 13 Jun 2018

AbstractforFertility preservation in Hodgkin’s lymphoma patients that undergo targeted molecular therapies: an important step forward from the chemotherapy era | Full Text | References | PDF (247.5 KB)

106 Views
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Original Research

Article

Multifocality is associated with central neck lymph node metastases in papillary thyroid microcarcinoma

Weihui Zheng, Kejing Wang, Junzhou Wu, Wendong Wang & Jinbiao Shang

Pages: 1527-1533

Published online: 14 Jun 2018

AbstractforMultifocality is associated with central neck lymph node metastases in papillary thyroid microcarcinoma | Full Text | References | PDF (323.9 KB)

57 Views
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Article

A nomogram to predict overall survival for biliary tract cancer

Wei Song, Zhi-gang Zhu, Qiong Wu, Chang-guang Lv, Yong-gang Wang, Lei Chen & Dong-liu Miao

Pages: 1535-1541

Published online: 14 Jun 2018

AbstractforA nomogram to predict overall survival for biliary tract cancer | Full Text | References | PDF (807.1 KB)

62 Views
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Article

Comparison of NSAIDs activity in COX-2 expressing and non-expressing 2D and 3D pancreatic cancer cell cultures

Ugnė Čeponytė, Miglė Paškevičiūtė & Vilma Petrikaitė

Pages: 1543-1551

Published online: 15 Jun 2018

AbstractforComparison of NSAIDs activity in COX-2 expressing and non-expressing 2D and 3D pancreatic cancer cell cultures | Full Text | References | PDF (3.2 MB)

177 Views
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Article

Expression of 4E-BP1 and phospho-4E-BP1 correlates with the prognosis of patients with clear cell renal carcinoma

Feng Li, Qingshui Wang, Xiaoxue Xiong, Chenyi Wang, Xiaohua Liu, Ziqiang Liao, Ke Li, Bifeng Xie & Yao Lin

Pages: 1553-1563

Published online: 15 Jun 2018

AbstractforExpression of 4E-BP1 and phospho-4E-BP1 correlates with the prognosis of patients with clear cell renal carcinoma | Full Text | References | PDF (6.9 MB)

55 Views
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Article

Knowledge, attitude, and practice toward the daily management of PICC in critically ill cancer patients discharged from intensive care units

Jie Chen, Hui Zhao, Zhijie Xia, Ying Zhang, Xiang Lv, Xuhui Zhou, Xiang Dong, Jingjie Li, Hong Jiang, Yan Huang & Huimin Huang

Pages: 1565-1574

Published online: 18 Jun 2018

AbstractforKnowledge, attitude, and practice toward the daily management of PICC in critically ill cancer patients discharged from intensive care units | Full Text | References | PDF (191.1 KB)

148 Views
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Article

Synaptopodin-2 plays an important role in the metastasis of breast cancer via PI3K/Akt/mTOR pathway

Erjie Xia, Xiaofen Zhou, Adheesh Bhandari, Xiaohua Zhang & Ouchen Wang

Pages: 1575-1583

Published online: 18 Jun 2018

AbstractforSynaptopodin-2 plays an important role in the metastasis of breast cancer via PI3K/Akt/mTOR pathway | Full Text | References | PDF (7.9 MB)

64 Views
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Article

INHBA upregulation correlates with poorer prognosis in patients with esophageal squamous cell carcinoma

Shanshan Lyu, Chao Jiang, Rui Xu, Yuhua Huang & Shumei Yan

Pages: 1585-1596

Published online: 18 Jun 2018

AbstractforINHBA upregulation correlates with poorer prognosis in patients with esophageal squamous cell carcinoma | Full Text | References | PDF (2.7 MB)

68 Views
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Article

An increased number of negative lymph nodes is associated with a higher immune response and longer survival in colon cancer patients

Wen-Zhuo He, Qian-Kun Xie, Wan-Ming Hu, Peng-fei Kong, Lin Yang, Yuan-Zhong Yang, Chang Jiang, Chen-Xi Yin, Hui-Juan Qiu, Hui-Zhong Zhang, Bei Zhang & Liang-Ping Xia

Pages: 1597-1604

Published online: 18 Jun 2018

AbstractforAn increased number of negative lymph nodes is associated with a higher immune response and longer survival in colon cancer patients | Full Text | References | PDF (603 KB)

63 Views
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Review

Review Article

Optimal management of resected gastric cancer

Riccardo Giampieri, Michela Del Prete, Luca Cantini, Maria Giuditta Baleani, Alessandro Bittoni, Elena Maccaroni & Rossana Berardi

Pages: 1605-1618

Published online: 21 Jun 2018

AbstractforOptimal management of resected gastric cancer | Full Text | References | PDF (308.6 KB)

59 Views
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Review Article

Role of key players in paradigm shifts of prostate cancer bone metastasis

Ayesha Sohail, Lubna Sherin, Saad I Butt, Sana Javed, Zhiwu Li, Sohail Iqbal & O Anwar Be’g

Pages: 1619-1626

Published online: 21 Jun 2018

AbstractforRole of key players in paradigm shifts of prostate cancer bone metastasis | Full Text | References | PDF (1 MB)

85 Views
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Review Article

Pioglitazone use in patients with diabetes and risk of bladder cancer: a systematic review and meta-analysis

Huaqing Yan, Haiyun Xie, Yufan Ying, Jiangfeng Li, Xiao Wang, Xin Xu & Xiangyi Zheng

Pages: 1627-1638

Published online: 22 Jun 2018

AbstractforPioglitazone use in patients with diabetes and risk of bladder cancer: a systematic review and meta-analysis | Full Text | References | PDF (557.9 KB)

105 Views
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Original Research

Article

The homogeneous and heterogeneous risk factors for the morbidity and prognosis of bone metastasis in patients with prostate cancer

Xu Guo, Chao Zhang, Qi Guo, Yao Xu, Guowei Feng, Lili Li, Xiuxin Han, Feng Lu, Yulin Ma, Xin Wang & Guowen Wang

Pages: 1639-1646

Published online: 22 Jun 2018

AbstractforThe homogeneous and heterogeneous risk factors for the morbidity and prognosis of bone metastasis in patients with prostate cancer | Full Text | References | PDF (1.1 MB)

79 Views
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Article

Decreased expression of TRPV1 in renal cell carcinoma: association with tumor Fuhrman grades and histopathological subtypes

Yong-Yang Wu, Xin-Yu Liu, De-Xiang Zhuo, Huai-Bin Huang, Fa-Biao Zhang & Shang-Fan Liao

Pages: 1647-1655

Published online: 22 Jun 2018

AbstractforDecreased expression of TRPV1 in renal cell carcinoma: association with tumor Fuhrman grades and histopathological subtypes | Full Text | References | PDF (6.1 MB)

59 Views
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Article

miRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case–control study involving 2,740 participants

Yu Chen, Weifeng Tang, Chao Liu, Jing Lin, Yafeng Wang, Sheng Zhang, Gang Chen & Xiongwei Zheng

Pages: 1657-1664

Published online: 25 Jun 2018

AbstractformiRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case–control study involving 2,740 participants | Full Text | References | PDF (214.2 KB)

57 Views
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Review

Review Article

Cancer risk assessment in modern radiotherapy workflow with medical big data

Fu Jin, Huan-Li Luo, Juan Zhou, Ya-Nan He, Xian-Feng Liu, Ming-Song Zhong, Han Yang, Chao Li, Qi-Cheng Li, Xia Huang, Xiu-Mei Tian, Da Qiu, Guang-Lei He, Li Yin & Ying Wang

Pages: 1665-1675

Published online: 22 Jun 2018

AbstractforCancer risk assessment in modern radiotherapy workflow with medical big data | Full Text | References | PDF (1,017.4 KB)

131 Views
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Original Research

Article

Cervical lymph node metastases in salivary gland adenoid cystic carcinoma: a systematic review and meta-analysis

Chunliu Ning, Tengfei Zhao, Zechen Wang, Delong Li, Yurong Kou & Shaohui Huang

Pages: 1677-1685

Published online: 22 Jun 2018

AbstractforCervical lymph node metastases in salivary gland adenoid cystic carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (988.4 KB)

95 Views
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Article

The prognostic value and clinicopathological features of sarcomatoid differentiation in patients with renal cell carcinoma: a systematic review and meta-analysis

Lijin Zhang, Bin Wu, Zhenlei Zha, Hu Zhao & Yejun Feng

Pages: 1687-1703

Published online: 22 Jun 2018

AbstractforThe prognostic value and clinicopathological features of sarcomatoid differentiation in patients with renal cell carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (1.6 MB)

64 Views
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Article

A retrospective study of concurrent chemoradiotherapy plus S-1 adjuvant chemotherapy on curative effect for treatment of patients with N3 stage nasopharyngeal carcinoma

Shuai Zhang, Liya Zhou, Xiaopeng Huang & Shaomin Lin

Pages: 1705-1711

Published online: 25 Jun 2018

AbstractforA retrospective study of concurrent chemoradiotherapy plus S-1 adjuvant chemotherapy on curative effect for treatment of patients with N3 stage nasopharyngeal carcinoma | Full Text | References | PDF (657.3 KB)

54 Views
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Article

The prognostic value of differentially expressed CYP3A subfamily members for hepatocellular carcinoma

Tingdong Yu, Xiangkun Wang, Guangzhi Zhu, Chuangye Han, Hao Su, Xiwen Liao, Chengkun Yang, Wei Qin, Ketuan Huang & Tao Peng

Pages: 1713-1726

Published online: 25 Jun 2018

AbstractforThe prognostic value of differentially expressed CYP3A subfamily members for hepatocellular carcinoma | Full Text | References | PDF (5.7 MB)

63 Views
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Article

The prognosis and effects of local treatment strategies for orbital embryonal rhabdomyosarcoma: a population-based study

Li-Ying Tang, Mou-Xin Zhang, Di-Han Lu, Yong-Xiong Chen, Zu-Guo Liu & San-Gang Wu

Pages: 1727-1734

Published online: 25 Jun 2018

AbstractforThe prognosis and effects of local treatment strategies for orbital embryonal rhabdomyosarcoma: a population-based study | Full Text | References | PDF (473.1 KB)

57 Views
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Article

Disparities in survival for right-sided vs. left-sided colon cancers in young patients: a study based on the Surveillance, Epidemiology, and End Results database (1990–2014)

Yaqi Wang, Lifeng Yang, Menglong Zhou, Lijun Shen, Jing Zhang, Weijuan Deng, Liping Liang, Ran Hu, Wang Yang, Ye Yao & Zhen Zhang

Pages: 1735-1747

Published online: 26 Jun 2018

AbstractforDisparities in survival for right-sided vs. left-sided colon cancers in young patients: a study based on the Surveillance, Epidemiology, and End Results database (1990–2014) | Full Text | References | PDF (521.4 KB)

87 Views
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Article

A panel containing PD-1, IL-2Rα, IL-10, and CA15-3 as a biomarker to discriminate breast cancer from benign breast disease

Chao Liu, Bing Sun, Bin Xu, Xiangying Meng, Lan Li, Yang Cong, Jiannan Liu, Qian Wang, Liang Xuan, Qibin Song & Shikai Wu

Pages: 1749-1761

Published online: 26 Jun 2018

AbstractforA panel containing PD-1, IL-2Rα, IL-10, and CA15-3 as a biomarker to discriminate breast cancer from benign breast disease | Full Text | References | PDF (3.2 MB)

78 Views
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Review

Review Article

Prognostic significance of the long noncoding RNAs in nasopharyngeal carcinoma: a systematic review and meta-analysis

HuanHuan Guo, Shuo Huang, Shuang Li, Hui Yu, ShiXiong Wu & XuHong Zhou

Pages: 1763-1779

Published online: 27 Jun 2018

AbstractforPrognostic significance of the long noncoding RNAs in nasopharyngeal carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (2.4 MB)

58 Views
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Original Research

Article

Decreased expression of peroxisome proliferator-activated receptor alpha indicates unfavorable outcomes in hepatocellular carcinoma

Yong-bo Xiao, Shao-hang Cai, Li-li Liu, Xia Yang & Jing-ping Yun

Pages: 1781-1789

Published online: 26 Jun 2018

AbstractforDecreased expression of peroxisome proliferator-activated receptor alpha indicates unfavorable outcomes in hepatocellular carcinoma | Full Text | References | PDF (3.2 MB)

70 Views
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Article

CYP17 polymorphisms are associated with decreased risk of breast cancer in Chinese Han women: a case–control study

Pengtao Yang, Meng Wang, Tian Tian, Yanjing Feng, Yi Zheng, Tielin Yang, Hongtao Li, Shuai Lin, Peng Xu, Yujiao Deng, Qian Hao, Na Li, Feng Guan & Zhijun Dai

Pages: 1791-1798

Published online: 03 Jul 2018

AbstractforCYP17 polymorphisms are associated with decreased risk of breast cancer in Chinese Han women: a case–control study | Full Text | References | PDF (279.1 KB)

64 Views
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Article

High expression of ALDOA and DDX5 are associated with poor prognosis in human colorectal cancer

Ling Dai, Guangdong Pan, Xiaojia Liu, Jiang Huang, Zhiqing Jiang, Xiaobao Zhu, Xinli Gan, Qing Xu & Ning Tan

Pages: 1799-1806

Published online: 29 Jun 2018

AbstractforHigh expression of ALDOA and DDX5 are associated with poor prognosis in human colorectal cancer | Full Text | References | PDF (2.4 MB)

76 Views
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Article

Polymorphisms in MYCN gene and neuroblastoma risk in Chinese children: a 3-center case–control study

Haixia Zhou, Zhenjian Zhuo, Shanshan Chen, Jie Zhao, Yixiao Mo, Jiao Zhang, Jing He & Jichen Ruan

Pages: 1807-1816

Published online: 02 Jul 2018

AbstractforPolymorphisms in MYCN gene and neuroblastoma risk in Chinese children: a 3-center case–control study | Full Text | References | PDF (393.9 KB)

56 Views
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Article

Downregulation of lncRNA OGFRP1 inhibits hepatocellular carcinoma progression by AKT/mTOR and Wnt/β-catenin signaling pathways

Wei Chen, Jia You, Qi Zheng & Yue-Yong Zhu

Pages: 1817-1826

Published online: 02 Jul 2018

AbstractforDownregulation of lncRNA OGFRP1 inhibits hepatocellular carcinoma progression by AKT/mTOR and Wnt/β-catenin signaling pathways | Full Text | References | PDF (5.4 MB)

75 Views
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Review

Review Article

Recent advances in antiemetics: new formulations of 5HT₃-receptor antagonists

James Gilmore, Steven D’Amato, Niesha Griffith & Lee Schwartzberg

Pages: 1827-1857

Published online: 03 Jul 2018

AbstractforRecent advances in antiemetics: new formulations of 5HT₃-receptor antagonists | Full Text | References | PDF (1.2 MB)

245 Views
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Review Article

Clinical usefulness of ¹⁸F-FDG PET/CT for the detection of distant metastases in patients with non-small cell lung cancer at initial staging: a meta-analysis

Binbin Yu, Xiaodong Zhu, Zhongguo Liang, Yongchu Sun, Wei Zhao & Kaihua Chen

Pages: 1859-1864

Published online: 04 Jul 2018

AbstractforClinical usefulness of ¹⁸F-FDG PET/CT for the detection of distant metastases in patients with non-small cell lung cancer at initial staging: a meta-analysis | Full Text | References | PDF (893.6 KB)

74 Views
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Original Research

Article

The effect of HIF-1α and PKM1 expression on acquisition of chemoresistance

Mitsuyoshi Okazaki, Sachio Fushida, Tomoya Tsukada, Jun Kinoshita, Katsunobu Oyama, Tomoharu Miyashita, Itasu Ninomiya, Shinichi Harada & Tetsuo Ohta

Pages: 1865-1874

Published online: 04 Jul 2018

AbstractforThe effect of HIF-1α and PKM1 expression on acquisition of chemoresistance | Full Text | References | PDF (2.9 MB)

68 Views
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Article

Prognostic and predictive value of the macroscopic growth pattern in patients undergoing curative resection of colorectal cancer: a single-institution retrospective cohort study of 4,080 Chinese patients

Xiao Li, Qi Zhao, Bang An, Jianni Qi, Wenwen Wang, Di Zhang, Zhen Li & Chengyong Qin

Pages: 1875-1887

Published online: 04 Jul 2018

AbstractforPrognostic and predictive value of the macroscopic growth pattern in patients undergoing curative resection of colorectal cancer: a single-institution retrospective cohort study of 4,080 Chinese patients | Full Text | References | PDF (2.8 MB)

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Review Article

Modern management for brain metastasis patients using stereotactic radiosurgery: literature review and the authors’ gamma knife treatment experiences

Yoshinori Higuchi, Masaaki Yamamoto, Toru Serizawa, Hitoshi Aiyama, Yasunori Sato & Bierta E Barfod

Pages: 1889-1899

Published online: 05 Jul 2018

AbstractforModern management for brain metastasis patients using stereotactic radiosurgery: literature review and the authors’ gamma knife treatment experiences | Full Text | References | PDF (172 KB)

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Original Research

Article

Safety and efficacy of denosumab in the treatment of pulmonary metastatic giant cell tumor of bone

Yi Luo, Fan Tang, Yitian Wang, Yong Zhou, Li Min, Wenli Zhang, Rui Shi, Hong Duan & Chongqi Tu

Pages: 1901-1906

Published online: 05 Jul 2018

AbstractforSafety and efficacy of denosumab in the treatment of pulmonary metastatic giant cell tumor of bone | Full Text | References | PDF (1.7 MB)

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Article

Benefit from the inclusion of surgery in the treatment of patients with stage III pancreatic cancer: a propensity-adjusted, population-based SEER analysis

Lai Wang, Chien-Shan Cheng, Lianyu Chen & Zhen Chen

Pages: 1907-1918

Published online: 05 Jul 2018

AbstractforBenefit from the inclusion of surgery in the treatment of patients with stage III pancreatic cancer: a propensity-adjusted, population-based SEER analysis | Full Text | References | PDF (4.3 MB)

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Article

Prognostic significance of Ki67 expression and the derived neutrophil–lymphocyte ratio in nasopharyngeal carcinoma

Liang Zhao, Haojun Chen, Bin Hu, Huan Zhang & Qin Lin

Pages: 1919-1926

Published online: 05 Jul 2018

AbstractforPrognostic significance of Ki67 expression and the derived neutrophil–lymphocyte ratio in nasopharyngeal carcinoma | Full Text | References | PDF (690.5 KB)

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Article

Recurrence risk after preoperative biopsy in patients with resected early-stage non-small-cell lung cancer: a retrospective study

Chengping Hu, Juan Jiang, Yuanyuan Li, Chunfang Zhang, Weixing Zhang, Haihe Jiang, Yang Gao, Wei Zhuang, Kaibo Lei, Yong Tang & Rongjun Wan

Pages: 1927-1934

Published online: 06 Jul 2018

AbstractforRecurrence risk after preoperative biopsy in patients with resected early-stage non-small-cell lung cancer: a retrospective study | Full Text | References | PDF (369.5 KB)

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Article

The prognostic significance of carcinoma-associated fibroblasts and tumor-associated macrophages in nasopharyngeal carcinoma

Yahui Yu, Liangru Ke, Xing Lv, Yi hong Ling, Jiabin Lu, Hu Liang, Wenze Qiu, Xinjun Huang, Guoying Liu, Wangzhong Li, Xiang Guo, Weixiong Xia & Yanqun Xiang

Pages: 1935-1946

Published online: 09 Jul 2018

AbstractforThe prognostic significance of carcinoma-associated fibroblasts and tumor-associated macrophages in nasopharyngeal carcinoma | Full Text | References | PDF (2.5 MB)

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Article

Direct comparison of five serum biomarkers in early diagnosis of hepatocellular carcinoma

Hongda Chen, Yue Zhang, Siwen Li, Ni Li, Yuhan Chen, Bei Zhang, Chunfeng Qu, Huiguo Ding, Jian Huang & Min Dai

Pages: 1947-1958

Published online: 10 Jul 2018

AbstractforDirect comparison of five serum biomarkers in early diagnosis of hepatocellular carcinoma | Full Text | References | PDF (2.8 MB)

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Article

Prognostic significance of lymph node metastasis and lymphadenectomy in early-stage ovarian carcinosarcoma

Wen-Peng Wang, Ning Li, Yuan-Yuan Zhang, Yu-Tao Gao, Yang-Chun Sun, Li Ge & Ling-Ying Wu

Pages: 1959-1968

Published online: 10 Jul 2018

AbstractforPrognostic significance of lymph node metastasis and lymphadenectomy in early-stage ovarian carcinosarcoma | Full Text | References | PDF (1,008 KB)

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Article

Neuropilin-1 expression is associated with lymph node metastasis in breast cancer tissues

Mahnaz Seifi-Alan, Roshanak Shams, Mojgan Bandehpour, Reza Mirfakhraie & Soudeh Ghafouri-Fard

Pages: 1969-1974

Published online: 11 Jul 2018

AbstractforNeuropilin-1 expression is associated with lymph node metastasis in breast cancer tissues | Full Text | References | PDF (478.2 KB)

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Article

Concurrent weekly single cisplatin vs triweekly cisplatin alone with radiotherapy for treatment of locally advanced cervical cancer: a meta-analysis

Jiahao Zhu, Shengjun Ji, Qunchao Hu, Qingqing Chen, Zhengcao Liu, Jinchang Wu & Wu Gu

Pages: 1975-1985

Published online: 12 Jul 2018

AbstractforConcurrent weekly single cisplatin vs triweekly cisplatin alone with radiotherapy for treatment of locally advanced cervical cancer: a meta-analysis | Full Text | References | PDF (659 KB)

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Review

Review Article

The miR-200 family: multiple effects on gliomas

Lilei Peng, Jie Fu & Yang Ming

Pages: 1987-1992

Published online: 13 Jul 2018

AbstractforThe miR-200 family: multiple effects on gliomas | Full Text | References | PDF (199.6 KB)

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Original Research

Article

Comparison of survival outcomes of locally advanced breast cancer patients receiving post-mastectomy radiotherapy with and without immediate breast reconstruction: a population-based analysis

San-Gang Wu, Wen-Wen Zhang, Jia-Yuan Sun, Qin Lin & Zhen-Yu He

Pages: 1993-2002

Published online: 13 Jul 2018

AbstractforComparison of survival outcomes of locally advanced breast cancer patients receiving post-mastectomy radiotherapy with and without immediate breast reconstruction: a population-based analysis | Full Text | References | PDF (941.6 KB)

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Review

Review Article

Evidence-based complementary treatment of pancreatic cancer: a review of adjunct therapies including paricalcitol, hydroxychloroquine, intravenous vitamin C, statins, metformin, curcumin, and aspirin

Stephen Bigelsen

Pages: 2003-2018

Published online: 13 Jul 2018

AbstractforEvidence-based complementary treatment of pancreatic cancer: a review of adjunct therapies including paricalcitol, hydroxychloroquine, intravenous vitamin C, statins, metformin, curcumin, and aspirin | Full Text | References | PDF (384.5 KB)

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Article

Predictive significance of preoperative CT findings for suboptimal cytoreduction in advanced ovarian cancer: a meta-analysis

Ting Wen Yi Hu, Dan Nie, Jin Hai Gou & Zheng Yu Li

Pages: 2019-2030

Published online: 16 Jul 2018

AbstractforPredictive significance of preoperative CT findings for suboptimal cytoreduction in advanced ovarian cancer: a meta-analysis | Full Text | References | PDF (1.8 MB)

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Article

Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer

Shi Jin, Shoubo Cao, Aleksei Grigorev, Jianhua Li, Qingwei Meng, Chunyan Wang, Meiyan Feng, Jing Hu, Feng Jiang & Yan Yu

Pages: 2031-2046

Published online: 16 Jul 2018

AbstractforEstablishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer | Full Text | References | PDF (10.8 MB)

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Article

Long-term survival effect of the interval between mastectomy and radiotherapy in locally advanced breast cancer

Wen-Wen Zhang, San-Gang Wu, Jia-Yuan Sun, Feng-Yan Li & Zhen-Yu He

Pages: 2047-2054

Published online: 16 Jul 2018

AbstractforLong-term survival effect of the interval between mastectomy and radiotherapy in locally advanced breast cancer | Full Text | References | PDF (1.2 MB)

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Article

Quantifying the prognostic significance of microRNA-17/17-5P in cancers: a meta-analysis based on published studies

Fujiao Duan, Yang Yang, Weigang Liu, Jie Zhao, Xiaoqin Song, Lifeng Li & Fuqin Li

Pages: 2055-2069

Published online: 17 Jul 2018

AbstractforQuantifying the prognostic significance of microRNA-17/17-5P in cancers: a meta-analysis based on published studies | Full Text | References | PDF (2.1 MB)

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Article

Nebivolol effect on doxorubicin-induced cardiotoxicity in breast cancer

Flavia Cochera, Daniel Dinca, Diana Aurora Bordejevic, Ioana Mihaela Citu, Adelina Marioara Mavrea, Minodora Andor, Mihai Trofenciuc & Mirela Cleopatra Tomescu

Pages: 2071-2081

Published online: 16 Jul 2018

AbstractforNebivolol effect on doxorubicin-induced cardiotoxicity in breast cancer | Full Text | References | PDF (6.6 MB)

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Article

Lymph node ratio as a valuable prognostic factor for patients with colorectal liver-only metastasis undergoing curative resection

Yuxiang Deng, Jianhong Peng, Yujie Zhao, Qiaoqi Sui, Ruixia Zhao, Zhenhai Lu, Miaozhen Qiu, Junzhong Lin & Zhizhong Pan

Pages: 2083-2094

Published online: 17 Jul 2018

AbstractforLymph node ratio as a valuable prognostic factor for patients with colorectal liver-only metastasis undergoing curative resection | Full Text | References | PDF (952.2 KB)

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Article

Right- and left-sided stage III colon cancers present different prognostic outcomes of oxaliplatin-based adjuvant chemotherapy after curative resection

Jianhong Peng, Cong Li, Fulong Wang, Huizhong Zhang, Weiwei Xiao, Hui Li, Zhenhai Lu, Zhizhong Pan, Xiaojun Wu & Rongxin Zhang

Pages: 2095-2103

Published online: 17 Jul 2018

AbstractforRight- and left-sided stage III colon cancers present different prognostic outcomes of oxaliplatin-based adjuvant chemotherapy after curative resection | Full Text | References | PDF (575.1 KB)

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Article

Differential diagnostic value of ¹⁸F-FDG PET/CT for benign and malignant vertebral compression fractures: comparison with magnetic resonance imaging

Xiaojiang He, Long Zhao, Xiuyu Guo, Liang Zhao, Jing Wu, Jingxiong Huang, Long Sun, Chengrong Xie & Haojun Chen

Pages: 2105-2115

Published online: 18 Jul 2018

AbstractforDifferential diagnostic value of ¹⁸F-FDG PET/CT for benign and malignant vertebral compression fractures: comparison with magnetic resonance imaging | Full Text | References | PDF (5.8 MB)

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Article

Higher frequency of occult lymph node metastasis in clinical N0 pulmonary adenocarcinoma with ALK rearrangement

Katsutoshi Seto, Hiroaki Kuroda, Tatsuya Yoshida, Shozo Sakata, Tetsuya Mizuno, Noriaki Sakakura, Toyoaki Hida, Yasushi Yatabe & Yukinori Sakao

Pages: 2117-2124

Published online: 18 Jul 2018

AbstractforHigher frequency of occult lymph node metastasis in clinical N0 pulmonary adenocarcinoma with ALK rearrangement | Full Text | References | PDF (465.2 KB)

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Article

Diagnostic and prognostic value of microRNAs in cholangiocarcinoma: a systematic review and meta-analysis

Chao Sun, Jie Zhu, Bin Wu, Jianlei Chen, Zhenwei Zhu, Peng Cai, Wanliang Guo, Zhicheng Gu, Jian Wang & Shungen Huang

Pages: 2125-2139

Published online: 18 Jul 2018

AbstractforDiagnostic and prognostic value of microRNAs in cholangiocarcinoma: a systematic review and meta-analysis | Full Text | References | PDF (1.6 MB)

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Article

Yi Que, Yao Liang, Jingjing Zhao, Ya Ding, Ruiqing Peng, Yuanxiang Guan & Xing Zhang

Pages: 2141-2150

Published online: 19 Jul 2018

AbstractforTreatment-related adverse effects with pazopanib, sorafenib and sunitinib in patients with advanced soft tissue sarcoma: a pooled analysis | Full Text | References | PDF (802.4 KB)

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Article

Preoperative circulating FPR and CCF score are promising biomarkers for predicting clinical outcome of stage II–III colorectal cancer patients

Fan Sun, Hong-Xin Peng, Qiu-Fang Gao, Shu-Qi Li, Jing Zhang, Qing-Gen Chen, Yu-Huan Jiang, Lei Zhang, Xiao-Zhong Wang & Hou-Qun Ying

Pages: 2151-2161

Published online: 19 Jul 2018

AbstractforPreoperative circulating FPR and CCF score are promising biomarkers for predicting clinical outcome of stage II–III colorectal cancer patients | Full Text | References | PDF (1.4 MB)

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Article

Prognostic value of primary tumor surgery in minor salivary-gland carcinoma patients with distant metastases at diagnosis: first evidence from a SEER-based study

Xiao Shi, Nai-Si Huang, Rong-Liang Shi, Wen-Jun Wei, Yu-Long Wang & Qing-Hai Ji

Pages: 2163-2172

Published online: 20 Jul 2018

AbstractforPrognostic value of primary tumor surgery in minor salivary-gland carcinoma patients with distant metastases at diagnosis: first evidence from a SEER-based study | Full Text | References | PDF (1.3 MB)

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Article

Disclosure of cancer diagnosis in China: the incidence, patients’ situation, and different preferences between patients and their family members and related influence factors

Yuxiu Liu, Jinhong Yang, Da Huo, Honghua Fan & Yufang Gao

Pages: 2173-2181

Published online: 23 Jul 2018

AbstractforDisclosure of cancer diagnosis in China: the incidence, patients’ situation, and different preferences between patients and their family members and related influence factors | Full Text | References | PDF (445.2 KB)

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Article

Prognostic implications of circulating Epstein–Barr virus DNA for extranodal natural killer/T-cell lymphoma, nasal type: a meta-analysis

Ruiwan Chen, Chengtao Wang, Yu Zhou & Bixiu Wen

Pages: 2183-2192

Published online: 20 Jul 2018

AbstractforPrognostic implications of circulating Epstein–Barr virus DNA for extranodal natural killer/T-cell lymphoma, nasal type: a meta-analysis | Full Text | References | PDF (918.5 KB)

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Article

Bevacizumab combined with chemotherapy vs single-agent therapy in recurrent glioblastoma: evidence from randomized controlled trials

Zhouqing Chen, Na Xu, Chongshun Zhao, Tao Xue, Xin Wu & Zhong Wang

Pages: 2193-2205

Published online: 23 Jul 2018

AbstractforBevacizumab combined with chemotherapy vs single-agent therapy in recurrent glioblastoma: evidence from randomized controlled trials | Full Text | References | PDF (3.3 MB)

63 Views
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Article

Profiles of differentially expressed circRNAs in esophageal and breast cancer

Peiyi Shi, Jian Sun, Biyu He, Huan Song, Zhongqi Li, Weimin Kong, Jianping Wang, Jianming Wang & Hengchuan Xue

Pages: 2207-2221

Published online: 23 Jul 2018

AbstractforProfiles of differentially expressed circRNAs in esophageal and breast cancer | Full Text | References | PDF (4.9 MB)

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Article

Evaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology

Krzysztof Kaliszewski, Dorota Diakowska, Beata Wojtczak & Zdzisław Forkasiewicz

Pages: 2223-2229

Published online: 23 Jul 2018

AbstractforEvaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology | Full Text | References | PDF (1.8 MB)

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Article

Prognostic value of subcutaneous adipose tissue volume in hepatocellular carcinoma treated with transcatheter intra-arterial therapy

Takamasa Kobayashi, Hirokazu Kawai, Oki Nakano, Satoshi Abe, Hiroteru Kamimura, Akira Sakamaki, Kenya Kamimura, Atsunori Tsuchiya, Masaaki Takamura, Satoshi Yamagiwa & Shuji Terai

Pages: 2231-2239

Published online: 25 Jul 2018

AbstractforPrognostic value of subcutaneous adipose tissue volume in hepatocellular carcinoma treated with transcatheter intra-arterial therapy | Full Text | References | PDF (1.5 MB)

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Article

PRAF2 expression indicates unfavorable clinical outcome in hepatocellular carcinoma

Chun-Hua Wang, Li-Li Liu, Ding-Zhun Liao, Mei-Fang Zhang, Jia Fu, Shi-Xun Lu, Shi-Lu Chen, Hong Wang, Shao-Hang Cai, Chris Zhiyi Zhang, Hui-Zhong Zhang & Jing-Ping Yun

Pages: 2241-2248

Published online: 25 Jul 2018

AbstractforPRAF2 expression indicates unfavorable clinical outcome in hepatocellular carcinoma | Full Text | References | PDF (5.4 MB)

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Review

Review Article

MicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer

Shuaixi Yang, Zhenqiang Sun, Quanbo Zhou, Weiwei Wang, Guixian Wang, Junmin Song, Zhen Li, Zhiyong Zhang, Yuan Chang, Kunkun Xia, Jinbo Liu & Weitang Yuan

Pages: 2249-2257

Published online: 26 Jul 2018

AbstractforMicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer | Full Text | References | PDF (1.5 MB)

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Original Research

Article

Disparities of age-based cancer-specific survival improvement with various clinicopathologic characteristics for kidney cancer

Kaitai Liu, Ping Wang, Xinli Zhu, Yanping Bei, Zhen Zheng & Senxiang Yan

Pages: 2259-2268

Published online: 27 Jul 2018

AbstractforDisparities of age-based cancer-specific survival improvement with various clinicopathologic characteristics for kidney cancer | Full Text | References | PDF (2.8 MB)

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Article

FAM98A promotes proliferation of non-small cell lung cancer cells via the P38-ATF2 signaling pathway

Rui Zheng, Quanbo Liu, Tianxu Wang, Lili Wang & Yong Zhang

Pages: 2269-2278

Published online: 27 Jul 2018

AbstractforFAM98A promotes proliferation of non-small cell lung cancer cells via the P38-ATF2 signaling pathway | Full Text | References | PDF (6.1 MB)

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Article

Pooling analysis on prognostic value of PHH3 expression in cancer patients

Qian Hao, Cong Dai, Yujiao Deng, Peng Xu, Tian Tian, Shuai Lin, Meng Wang, Kang Liu, Dingli Song, Ying Wu, Yan Guo & Zhijun Dai

Pages: 2279-2288

Published online: 30 Jul 2018

AbstractforPooling analysis on prognostic value of PHH3 expression in cancer patients | Full Text | References | PDF (2.5 MB)

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Review

Review Article

Development of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer

Jing-hua Pan, Hong Zhou, Sheng-bin Zhu, Jin-lian Huang, Xiao-xu Zhao, Hui Ding & Yun-long Pan

Pages: 2289-2301

Published online: 01 Aug 2018

AbstractforDevelopment of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer | Full Text | References | PDF (6.6 MB)

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Original Research

Article

P–TNM staging system for colon cancer: combination of P-stage and AJCC TNM staging system for improving prognostic prediction and clinical management

Qi Liu, Dakui Luo, Sanjun Cai, Qingguo Li & Xinxiang Li

Pages: 2303-2314

Published online: 31 Jul 2018

AbstractforP–TNM staging system for colon cancer: combination of P-stage and AJCC TNM staging system for improving prognostic prediction and clinical management | Full Text | References | PDF (1.6 MB)

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Article

Human leukocyte antigen gene polymorphisms are associated with systemic inflammation in hepatitis B virus-related hepatocellular carcinoma

Xiao-long Wu, Zhi-yu Li, Xin-yu Bi, Hong Zhao, Jian-jun Zhao, Jian-guo Zhou, Yue Han, Zhen Huang, Ye-fan Zhang & Jian-qiang Cai

Pages: 2315-2324

Published online: 31 Jul 2018

AbstractforHuman leukocyte antigen gene polymorphisms are associated with systemic inflammation in hepatitis B virus-related hepatocellular carcinoma | Full Text | References | PDF (850.4 KB)

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Review

Review Article

Targeting energy metabolism to eliminate cancer cells

Shazwin Hani Shahruzaman, Sharida Fakurazi & Sandra Maniam

Pages: 2325-2335

Published online: 31 Jul 2018

AbstractforTargeting energy metabolism to eliminate cancer cells | Full Text | References | PDF (861.6 KB)

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Original Research

Article

Bioinformatic analysis of four miRNAs relevant to metastasis-regulated processes in endometrial carcinoma

Lingping Zhu, Zhiqun Shu & Xiaoming Sun

Pages: 2337-2346

Published online: 01 Aug 2018

AbstractforBioinformatic analysis of four miRNAs relevant to metastasis-regulated processes in endometrial carcinoma | Full Text | References | PDF (5.3 MB)

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Article

Establishment and external validation of a prognostic model for predicting disease-free survival and risk stratification in breast cancer patients treated with neoadjuvant chemotherapy

Jianguo Lai, Hongli Wang, Jingwen Peng, Peixian Chen & Zihao Pan

Pages: 2347-2356

Published online: 01 Aug 2018

AbstractforEstablishment and external validation of a prognostic model for predicting disease-free survival and risk stratification in breast cancer patients treated with neoadjuvant chemotherapy | Full Text | References | PDF (924 KB)

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Article

Intermittent androgen deprivation therapy: recommendations to improve the management of patients with prostate cancer following the GRADE approach

Xavier Bonfill, Ingrid Arevalo-Rodriguez, Laura Martínez García, Maria Jesús Quintana, Diana Buitrago-Garcia, Diego Lobos Urbina, José Antonio Cordero & On behalf of the IADT Spanish Study Group

Pages: 2357-2367

Published online: 02 Aug 2018

AbstractforIntermittent androgen deprivation therapy: recommendations to improve the management of patients with prostate cancer following the GRADE approach | Full Text | References | PDF (1.5 MB)

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Article

Decreased expression of COLEC10 predicts poor overall survival in patients with hepatocellular carcinoma

Baozhu Zhang & Haibo Wu

Pages: 2369-2375

Published online: 01 Aug 2018

AbstractforDecreased expression of COLEC10 predicts poor overall survival in patients with hepatocellular carcinoma | Full Text | References | PDF (2.5 MB)

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Article

Lack of association between the risk of prostate cancer and vitamin D receptor Bsm I polymorphism: a meta-analysis of 27 published studies

Shaosan Kang, Yansheng Zhao, Lei Wang, Jian Liu, Xi Chen, Xiaofeng Liu, Zhijie Shi, Weixing Gao & Fenghong Cao

Pages: 2377-2387

Published online: 01 Aug 2018

AbstractforLack of association between the risk of prostate cancer and vitamin D receptor Bsm I polymorphism: a meta-analysis of 27 published studies | Full Text | References | PDF (1.1 MB)

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Article

LRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21

Lijia Xiao, Yuliang Wang, Weicheng Liang, Liping Liu, Nannan Pan, Huimin Deng, Luqian Li, Chang Zou, Franky Leung Chan & Yiwen Zhou

Pages: 2389-2400

Published online: 01 Aug 2018

AbstractforLRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21 | Full Text | References | PDF (5.9 MB)

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Article

Surgical significance and efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in patients with primary lung adenosquamous carcinoma

Chao Zhang, Haitang Yang, Baoping Lang, Xiangdong Yu, Peng Xiao, Dian Zhang, Liwen Fan & Xiao Zhang

Pages: 2401-2407

Published online: 02 Aug 2018

AbstractforSurgical significance and efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in patients with primary lung adenosquamous carcinoma | Full Text | References | PDF (587.2 KB)

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Article

Pretreatment NRS-2002 scores combined with hematologic inflammation markers are independent prognostic factors in patients with resectable thoracic esophageal squamous cell carcinoma

Xin-Wei Guo, Yang-Chen Liu, Fei Gao, Sheng-Jun Ji, Ju-Ying Zhou, Lei Ji & Shao-Bing Zhou

Pages: 2409-2418

Published online: 02 Aug 2018

AbstractforPretreatment NRS-2002 scores combined with hematologic inflammation markers are independent prognostic factors in patients with resectable thoracic esophageal squamous cell carcinoma | Full Text | References | PDF (1.3 MB)

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Article

TMEM17 promotes malignant progression of breast cancer via AKT/GSK3β signaling

Yue Zhao, Kuiyuan Song, Yong Zhang, Hongtao Xu, Xiupeng Zhang, Liang Wang, Chuifeng Fan, Guiyang Jiang & Enhua Wang

Pages: 2419-2428

Published online: 02 Aug 2018

AbstractforTMEM17 promotes malignant progression of breast cancer via AKT/GSK3β signaling | Full Text | References | PDF (6.8 MB)

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Review

Review Article

Overview of advances in vasculogenic mimicry – a potential target for tumor therapy

Hong Ge & Hui Luo

Pages: 2429-2437

Published online: 02 Aug 2018

AbstractforOverview of advances in vasculogenic mimicry – a potential target for tumor therapy | Full Text | References | PDF (1.9 MB)

173 Views
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Review Article

Tracking steps in oncology: the time is now

Juhi M Purswani, Nitin Ohri & Colin Champ

Pages: 2439-2447

Published online: 03 Aug 2018

AbstractforTracking steps in oncology: the time is now | Full Text | References | PDF (200 KB)

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Original Research

Article

Model of lymph node metastasis posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma

Yi Luo, Xiao-Cheng Xu, Jie Shen, Jing-Jing Shi, Si Lu, Wei He, Jian-Yong Lei & Ding-Cun Luo

Pages: 2449-2455

Published online: 06 Aug 2018

AbstractforModel of lymph node metastasis posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma | Full Text | References | PDF (281.7 KB)

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Article

Clinical and biological implications of IDH1/2 in acute myeloid leukemia with DNMT3A^mut

Xinpei Zhang, Jinlong Shi, Jilei Zhang, Xinrui Yang, Gaoqi Zhang, Siyuan Yang, Jing Wang, Xiaoyan Ke & Lin Fu

Pages: 2457-2466

Published online: 06 Aug 2018

AbstractforClinical and biological implications of IDH1/2 in acute myeloid leukemia with DNMT3A^mut | Full Text | References | PDF (1.6 MB)

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Article

Bone metastasis predicts poor prognosis of patients with brain metastases from colorectal carcinoma post aggressive treatment

Hao Duan, Zhen-Qiang He, Cheng-Cheng Guo, Jue-Hui Li, Jian Wang, Zhe Zhu, Ke Sai, Zhong-Ping Chen, Xiao-Bing Jiang & Yong-Gao Mou

Pages: 2467-2474

Published online: 06 Aug 2018

AbstractforBone metastasis predicts poor prognosis of patients with brain metastases from colorectal carcinoma post aggressive treatment | Full Text | References | PDF (597.8 KB)

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Review

Review Article

Current landscape and future directions of biomarkers for predicting responses to immune checkpoint inhibitors

Yingming Zhu, Fen Zhao, Zhenxiang Li & Jinming Yu

Pages: 2475-2488

Published online: 07 Aug 2018

AbstractforCurrent landscape and future directions of biomarkers for predicting responses to immune checkpoint inhibitors | Full Text | References | PDF (982.2 KB)

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Original Research

Article

Biological and clinical influences of NPM1 in acute myeloid leukemia patients with DNMT3A mutations

Xinrui Yang, Jinlong Shi, Xinpei Zhang, Gaoqi Zhang, Jilei Zhang, Siyuan Yang, Jing Wang, Xiaoyan Ke & Lin Fu

Pages: 2489-2497

Published online: 07 Aug 2018

AbstractforBiological and clinical influences of NPM1 in acute myeloid leukemia patients with DNMT3A mutations | Full Text | References | PDF (1,016 KB)

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Article

Association of low skeletal muscle index with increased systematic inflammatory responses and interferon γ-induced protein 10 levels in patients with colon cancer

Wen-Zhuo He, Qiu-Xia Yang, Jin-Ye Xie, Peng-Fei Kong, Wan-Ming Hu, Lin Yang, Yuan-Zhong Yang, Qian-Kun Xie, Chang Jiang, Chen-Xi Yin, Gui-Fang Guo, Hui-Juan Qiu, Bei Zhang & Liang-Ping Xia

Pages: 2499-2507

Published online: 07 Aug 2018

AbstractforAssociation of low skeletal muscle index with increased systematic inflammatory responses and interferon γ-induced protein 10 levels in patients with colon cancer | Full Text | References | PDF (1.4 MB)

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Article

Adjuvant chemotherapy for stage II colon cancer: who really needs it

Yan Yang, Yang Yang, Hui Yang, Fen Wang, Huihui Wang, Qi Chen, Ying Liu, Aiying Li & Quanan Zhang

Pages: 2509-2520

Published online: 08 Aug 2018

AbstractforAdjuvant chemotherapy for stage II colon cancer: who really needs it | Full Text | References | PDF (1.3 MB)

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Article

Novel endocrine therapeutic strategy in endometrial carcinoma targeting estrogen-related receptor α by XCT790 and siRNA

PengMing Sun, XiaoDan Mao, Min Gao, MeiMei Huang, LiLi Chen, GuanYu Ruan, WeiYi Huang, Elena Ioana Braicu & Jalid Sehouli

Pages: 2521-2535

Published online: 10 Aug 2018

AbstractforNovel endocrine therapeutic strategy in endometrial carcinoma targeting estrogen-related receptor α by XCT790 and siRNA | Full Text | References | PDF (7.3 MB)

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Article

Genome-scale analysis to identify prognostic microRNA biomarkers in patients with early stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy

Xiwen Liao, Xiangkun Wang, Ketuan Huang, Chengkun Yang, Tingdong Yu, Chuangye Han, Guangzhi Zhu, Hao Su, Rui Huang & Tao Peng

Pages: 2537-2551

Published online: 10 Aug 2018

AbstractforGenome-scale analysis to identify prognostic microRNA biomarkers in patients with early stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy | Full Text | References | PDF (8.1 MB)

79 Views
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Article

The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials

Xiao Xia Guo, Hong Li Wu, Hong Yun Shi, Lei Su & Xi Zhang

Pages: 2553-2562

Published online: 10 Aug 2018

AbstractforThe efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials | Full Text | References | PDF (909.9 KB)

167 Views
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Article

E2F1 induces LSINCT5 transcriptional activity and promotes gastric cancer progression by affecting the epithelial-mesenchymal transition

Peng Qi, Wan-run Lin, Meng Zhang, Dan Huang, Shu-juan Ni, Xiao-li Zhu, Qian-ming Bai, Wei-qi Sheng, Xiang Du & Xiao-yan Zhou

Pages: 2563-2571

Published online: 10 Aug 2018

AbstractforE2F1 induces LSINCT5 transcriptional activity and promotes gastric cancer progression by affecting the epithelial-mesenchymal transition | Full Text | References | PDF (1.6 MB)

68 Views
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Review

Review Article

Clinical value of circulating ESR1 mutations for patients with metastatic breast cancer: a meta-analysis

Kai Zhang, Ruoxi Hong, Fei Xu, Wen Xia, Lee Kaping, Ge Qin, Qiufan Zheng, Qianyi Lu, Yan Xia Shi, Zhong Yu Yuan & Shusen Wang

Pages: 2573-2580

Published online: 14 Aug 2018

AbstractforClinical value of circulating ESR1 mutations for patients with metastatic breast cancer: a meta-analysis | Full Text | References | PDF (726.9 KB)

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Original Research

Article

Short- and long-term outcomes of laparoscopic hepatectomy for colorectal liver metastases in elderly patients

Meng Yue, Shiquan Li, Guoqiang Yan, Chenyao Li & Zhenhua Kang

Pages: 2581-2587

Published online: 10 Aug 2018

AbstractforShort- and long-term outcomes of laparoscopic hepatectomy for colorectal liver metastases in elderly patients | Full Text | References | PDF (420.4 KB)

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Review

Review Article

Association of IL-8 gene promoter −251 A/T and IL-18 gene promoter −137 G/C polymorphisms with head and neck cancer risk: a comprehensive meta-analysis

Zheng Wang, Zi-Ming Gao, Hai-Bo Huang, Li-Sha Sun, An-Qi Sun & Kai Li

Pages: 2589-2604

Published online: 10 Aug 2018

AbstractforAssociation of IL-8 gene promoter −251 A/T and IL-18 gene promoter −137 G/C polymorphisms with head and neck cancer risk: a comprehensive meta-analysis | Full Text | References | PDF (1.5 MB)

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Original Research

Article

Risk factors for gastric intraepithelial neoplasia in Chinese adults: a case–control study

Yanqiu Yu, Cheng Fang, Chunyan Peng, Shanshan Shen, Guifang Xu, Qi Sun, Lin Li, Chuan Su & Xiaoping Zou

Pages: 2605-2613

Published online: 13 Aug 2018

AbstractforRisk factors for gastric intraepithelial neoplasia in Chinese adults: a case–control study | Full Text | References | PDF (1.3 MB)

95 Views
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Article

AP-2α expression in papillary thyroid carcinoma predicts tumor progression and poor prognosis

Hong Rong Wu & Jian Zhang

Pages: 2615-2625

Published online: 13 Aug 2018

AbstractforAP-2α expression in papillary thyroid carcinoma predicts tumor progression and poor prognosis | Full Text | References | PDF (5.7 MB)

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Article

Upregulated expression of miR-421 is associated with poor prognosis in non-small-cell lung cancer

Yunxia Li, Xiaomei Cui, Yongdeng Li, Tingting Zhang & Shuyun Li

Pages: 2627-2633

Published online: 13 Aug 2018

AbstractforUpregulated expression of miR-421 is associated with poor prognosis in non-small-cell lung cancer | Full Text | References | PDF (611 KB)

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Article

Use of FLT3 inhibitors in acute myeloid leukemia remission induction or salvage therapy: systematic review and meta-analysis

Minglei Yang, Jian Zhao, Tielong Liu, Xinghai Yang, Haifeng Wei, Wei Xu & Jianru Xiao

Pages: 2635-2652

Published online: 14 Aug 2018

AbstractforUse of FLT3 inhibitors in acute myeloid leukemia remission induction or salvage therapy: systematic review and meta-analysis | Full Text | References | PDF (3.1 MB)

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Article

IL-17 and colorectal cancer risk in the Middle East: gene polymorphisms and expression

Omar A Al Obeed, Mansoor-Ali Vaali-Mohamed, Khayal A Alkhayal, Thamer A Bin Traiki, Ahmad M Zubaidi, Maha Arafah, Robert A Harris, Zahid Khan & Maha-Hamadien Abdulla

Pages: 2653-2661

Published online: 05 Sep 2018

AbstractforIL-17 and colorectal cancer risk in the Middle East: gene polymorphisms and expression | Full Text | References | PDF (947.6 KB)

109 Views
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Article

Proximal shift of colorectal cancer with increasing age in different ethnicities

Lin Yang, Zhenchong Xiong, Wenzhuo He, Kunqian Xie, Shousheng Liu, Pengfei Kong, Chang Jiang, Guifang Guo & Liangping Xia

Pages: 2663-2673

Published online: 15 Aug 2018

AbstractforProximal shift of colorectal cancer with increasing age in different ethnicities | Full Text | References | PDF (1.3 MB)

81 Views
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Article

Dose-escalated radiotherapy improved survival for esophageal cancer patients with a clinical complete response after standard-dose radiotherapy with concurrent chemotherapy

Wei Zhang, Yijun Luo, Xiaoli Wang, Gaohua Han, Peng Wang, Wei Yuan & Sheng-Bin Dai

Pages: 2675-2682

Published online: 14 Aug 2018

AbstractforDose-escalated radiotherapy improved survival for esophageal cancer patients with a clinical complete response after standard-dose radiotherapy with concurrent chemotherapy | Full Text | References | PDF (656.7 KB)

87 Views
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Article

A network-based signature to predict the survival of non-smoking lung adenocarcinoma

Qixing Mao, Louqian Zhang, Yi Zhang, Gaochao Dong, Yao Yang, Wenjie Xia, Bing Chen, Weidong Ma, Jianzhong Hu, Feng Jiang & Lin Xu

Pages: 2683-2693

Published online: 16 Aug 2018

AbstractforA network-based signature to predict the survival of non-smoking lung adenocarcinoma | Full Text | References | PDF (6.5 MB)

66 Views
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Article

Nonsteroidal anti-inflammatory drugs, especially aspirin, are linked to lower risk and better survival of hepatocellular carcinoma: a meta-analysis

Yuquan Tao, Yesheng Li, Xing Liu, Qing Deng, Yongchun Yu & Zongguo Yang

Pages: 2695-2709

Published online: 15 Aug 2018

AbstractforNonsteroidal anti-inflammatory drugs, especially aspirin, are linked to lower risk and better survival of hepatocellular carcinoma: a meta-analysis | Full Text | References | PDF (8.8 MB)

55 Views
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Review

Review Article

lncRNA PVT1 identified as an independent biomarker for prognosis surveillance of solid tumors based on transcriptome data and meta-analysis

Xiaoliang Chen, Yueying Yang, Yong Cao, Changjun Wu, Shuxian Wu, Zhan Su, Hongwei Jin, Dongli Wang, Gengxin Zhang, Wei Fan, Jinbo Lin, Yunhong Zeng & Dongsheng Hu

Pages: 2711-2727

Published online: 16 Aug 2018

AbstractforlncRNA PVT1 identified as an independent biomarker for prognosis surveillance of solid tumors based on transcriptome data and meta-analysis | Full Text | References | PDF (1.4 MB)

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Original Research

Article

Low-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial–mesenchymal transition and acts synergistically with 5-fluorouracil

Toru Kurata, Sachio Fushida, Jun Kinoshita, Katsunobu Oyama, Takahisa Yamaguchi, Mitsuyoshi Okazaki, Tomoharu Miyashita, Hidehiro Tajima, Itasu Ninomiya & Tetsuo Ohta

Pages: 2729-2742

Published online: 15 Aug 2018

AbstractforLow-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial–mesenchymal transition and acts synergistically with 5-fluorouracil | Full Text | References | PDF (6.6 MB)

73 Views
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Article

Prevalence and characteristics of colonic adenoma in mainland China

Wandong Hong, Lemei Dong, Simon Stock, Zarrin Basharat, Maddalena Zippi & Mengtao Zhou

Pages: 2743-2755

Published online: 16 Aug 2018

AbstractforPrevalence and characteristics of colonic adenoma in mainland China | Full Text | References | PDF (3.2 MB)

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Article

High Spy1 expression predicts poor prognosis in colorectal cancer

Qin Jin, Gang Liu, Luri Bao, Yuzhen Ma, Huidong Qi, Zhizhong Yun, Yanfeng Dai & Shu Zhang

Pages: 2757-2765

Published online: 16 Aug 2018

AbstractforHigh Spy1 expression predicts poor prognosis in colorectal cancer | Full Text | References | PDF (4 MB)

53 Views
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Article

G-CSF associates with neurogenesis and predicts prognosis and sensitivity to chemotherapy in pancreatic ductal adenocarcinoma

Lingfu Zhang, Lianyuan Tao, Limei Guo, Jun Zhan, Chunhui Yuan, Zhaolai Ma, Bin Jiang & Dianrong Xiu

Pages: 2767-2775

Published online: 17 Aug 2018

AbstractforG-CSF associates with neurogenesis and predicts prognosis and sensitivity to chemotherapy in pancreatic ductal adenocarcinoma | Full Text | References | PDF (4.3 MB)

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Article

The expression profile and clinical application potential of hsa_circ_0000711 in colorectal cancer

Jinyun Li, Shumin Ni, Chongchang Zhou & Meng Ye

Pages: 2777-2784

Published online: 17 Aug 2018

AbstractforThe expression profile and clinical application potential of hsa_circ_0000711 in colorectal cancer | Full Text | References | PDF (2.5 MB)

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Article

Prognostic value of inflammation-based prognostic index in patients with nasopharyngeal carcinoma: a propensity score matching study

Ronald Wihal Oei, Lulu Ye, Fangfang Kong, Chengrun Du, Ruiping Zhai, Tingting Xu, Chunying Shen, Xiaoshen Wang, Xiayun He, Lin Kong, Chaosu Hu & Hongmei Ying

Pages: 2785-2797

Published online: 17 Aug 2018

AbstractforPrognostic value of inflammation-based prognostic index in patients with nasopharyngeal carcinoma: a propensity score matching study | Full Text | References | PDF (3.3 MB)

68 Views
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Article

LncRNA TINCR is associated with clinical progression and serves as tumor suppressive role in prostate cancer

Liming Dong, Honglin Ding, Yanpei Li, Dongwei Xue & Yili Liu

Pages: 2799-2807

Published online: 20 Aug 2018

AbstractforLncRNA TINCR is associated with clinical progression and serves as tumor suppressive role in prostate cancer | Full Text | References | PDF (2 MB)

67 Views
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Article

The association of HIF-1α expression with clinicopathological significance in prostate cancer: a meta-analysis

Meng Huang, Hexi Du, Li Zhang, Hong Che & Chaozhao Liang

Pages: 2809-2816

Published online: 21 Aug 2018

AbstractforThe association of HIF-1α expression with clinicopathological significance in prostate cancer: a meta-analysis | Full Text | References | PDF (1.5 MB)

56 Views
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Article

Treatment options for refractory/relapsed multiple myeloma: an updated evidence synthesis by network meta-analysis

Xian-Wu Luo, Xue-Qing Du, Jie-Li Li, Xiao-Ping Liu & Xiang-Yu Meng

Pages: 2817-2823

Published online: 21 Aug 2018

AbstractforTreatment options for refractory/relapsed multiple myeloma: an updated evidence synthesis by network meta-analysis | Full Text | References | PDF (362.9 KB)

67 Views
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Article

MicroRNA-200b expression level is negatively associated with pathological grading in human gliomas

Xiangyi Kong, Shun Gong, Tao Yan & Yi Yang

Pages: 2825-2834

Published online: 24 Aug 2018

AbstractforMicroRNA-200b expression level is negatively associated with pathological grading in human gliomas | Full Text | References | PDF (939.6 KB)

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Article

Tissue transglutaminase 2 expression is epigenetically regulated in human lung cancer cells and prevents reactive oxygen species-induced apoptosis

Ming-Yang Lee, Ming-Fang Wu, Shur-Hueih Cherng, Ling-Yen Chiu, Tsung-Ying Yang & Gwo-Tarng Sheu

Pages: 2835-2848

Published online: 23 Aug 2018

AbstractforTissue transglutaminase 2 expression is epigenetically regulated in human lung cancer cells and prevents reactive oxygen species-induced apoptosis | Full Text | References | PDF (5.5 MB)

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Article

Gfi-1 promotes proliferation of human cervical carcinoma via targeting of FBW7 ubiquitin ligase expression

Hongbing Cai, Fan Zhang & Zhen Li

Pages: 2849-2857

Published online: 23 Aug 2018

AbstractforGfi-1 promotes proliferation of human cervical carcinoma via targeting of FBW7 ubiquitin ligase expression | Full Text | References | PDF (3.5 MB)

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Article

Using LC–MS/MS-based targeted proteomics to monitor the pattern of ABC transporters expression in the development of drug resistance

Fanqi Meng, Le Zou, Tengyu Zhang, Lei Jiang, Yao Ding, Peng Yu & Jie Peng

Pages: 2859-2870

Published online: 23 Aug 2018

AbstractforUsing LC–MS/MS-based targeted proteomics to monitor the pattern of ABC transporters expression in the development of drug resistance | Full Text | References | PDF (2.1 MB)

67 Views
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Article

Differences in clinical characteristics and mutational pattern between synchronous and metachronous colorectal liver metastases

Peng Zheng, Li Ren, Qingyang Feng, Dexiang Zhu, Wenju Chang, Guodong He, Meiling Ji, Mi Jian, Qi Lin, Tuo Yi, Ye Wei & Jianmin Xu

Pages: 2871-2881

Published online: 27 Aug 2018

AbstractforDifferences in clinical characteristics and mutational pattern between synchronous and metachronous colorectal liver metastases | Full Text | References | PDF (1.6 MB)

64 Views
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Article

Long-term oncologic outcomes of papillary thyroid microcarcinoma according to the presence of clinically apparent lymph node metastasis: a large retrospective analysis of 5,348 patients

Jung Bum Choi, Woo Kyung Lee, Seul Gi Lee, Haengrang Ryu, Cho Rok Lee, Sang Wook Kang, Jong Ju Jeong, Kee-Hyun Nam, Eun Jig Lee, Woong Youn Chung, Young Suk Jo & Jandee Lee

Pages: 2883-2891

Published online: 27 Aug 2018

AbstractforLong-term oncologic outcomes of papillary thyroid microcarcinoma according to the presence of clinically apparent lymph node metastasis: a large retrospective analysis of 5,348 patients | Full Text | References | PDF (328.4 KB)

80 Views
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Review

Review Article

The role of CCN4/WISP-1 in the cancerous phenotype

Mary P Nivison & Kathryn E Meier

Pages: 2893-2903

Published online: 27 Aug 2018

AbstractforThe role of CCN4/WISP-1 in the cancerous phenotype | Full Text | References | PDF (994.3 KB)

99 Views
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Original Research

Article

Trichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells

Yan Geng, Jing Liu, Ying Xie, Hongmei Jiang, Kai Zuo, Tao Li & Zhiqiang Liu

Pages: 2905-2914

Published online: 28 Aug 2018

AbstractforTrichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells | Full Text | References | PDF (3.1 MB)

71 Views
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Article

Efficacy and safety of TAS-102 in refractory metastatic colorectal cancer: a meta-analysis

Duke Chen, Yu-Shen Wu, Huapeng Lin, Yihan Wang, Longhao Li & Tao Zhang

Pages: 2915-2924

Published online: 28 Aug 2018

AbstractforEfficacy and safety of TAS-102 in refractory metastatic colorectal cancer: a meta-analysis | Full Text | References | PDF (1.1 MB)

66 Views
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Article

TNM-PNI: a novel prognostic scoring system for patients with gastric cancer and curative D2 resection

Zi-Ming Gao, Rui-Ying Wang, Peng Deng, Peng Ding, Chen Zheng, Bin Hou & Kai Li

Pages: 2925-2933

Published online: 28 Aug 2018

AbstractforTNM-PNI: a novel prognostic scoring system for patients with gastric cancer and curative D2 resection | Full Text | References | PDF (751.1 KB)

57 Views
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Article

Incidence of bone metastasis and factors contributing to its development and prognosis in newly diagnosed renal cell carcinoma: a population-based study

Qi Guo, Chao Zhang, Xu Guo, Fang Tao, Yao Xu, Guowei Feng, Xiuxin Han, Zhiwu Ren, Hui Zhang, Pingfang Zhang, Xin Wang & Guowen Wang

Pages: 2935-2944

Published online: 28 Aug 2018

AbstractforIncidence of bone metastasis and factors contributing to its development and prognosis in newly diagnosed renal cell carcinoma: a population-based study | Full Text | References | PDF (1.4 MB)

72 Views
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Article

Computational analysis of mRNA expression profiles identifies a novel triple-biomarker model as prognostic predictor of stage II and III colorectal adenocarcinoma patients

Xiankui Cheng, Meilin Hu, Chuancui Chen & Dongsheng Hou

Pages: 2945-2952

Published online: 28 Aug 2018

AbstractforComputational analysis of mRNA expression profiles identifies a novel triple-biomarker model as prognostic predictor of stage II and III colorectal adenocarcinoma patients | Full Text | References | PDF (3.3 MB)

53 Views
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Article

Diagnostic potential of methylated DAPK in brushing samples of nasopharyngeal carcinoma

Jian Zhang, Zhisen Shen, Huigao Liu, Shuai Liu & Wenxiu Shu

Pages: 2953-2964

Published online: 28 Aug 2018

AbstractforDiagnostic potential of methylated DAPK in brushing samples of nasopharyngeal carcinoma | Full Text | References | PDF (9.5 MB)

60 Views
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Article

Relationship between IGF2BP2 and IGFBP3 polymorphisms and susceptibility to non-small-cell lung cancer: a case–control study in Eastern Chinese Han population

Shuchen Chen, Hao Qiu, Chao Liu, Yafeng Wang, Weifeng Tang & Mingqiang Kang

Pages: 2965-2975

Published online: 28 Aug 2018

AbstractforRelationship between IGF2BP2 and IGFBP3 polymorphisms and susceptibility to non-small-cell lung cancer: a case–control study in Eastern Chinese Han population | Full Text | References | PDF (190.6 KB)

63 Views
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Article

Treatment outcomes of ureteral stenting for malignant extrinsic ureteral obstruction: a comparison between polymeric and metallic stents

Jumpei Asakawa, Taro Iguchi, Satoshi Tamada, Noriko Ninomiya, Minoru Kato, Takeshi Yamasaki & Tatsuya Nakatani

Pages: 2977-2982

Published online: 28 Aug 2018

AbstractforTreatment outcomes of ureteral stenting for malignant extrinsic ureteral obstruction: a comparison between polymeric and metallic stents | Full Text | References | PDF (257.5 KB)

64 Views
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Article

Elevated serum LAMC2 is associated with lymph node metastasis and predicts poor prognosis in penile squamous cell carcinoma

Qiang-Hua Zhou, Chuang-Zhong Deng, Jie-Ping Chen, Kang-Bo Huang, Ting-Yu Liu, Kai Yao, Zhuo-Wei Liu, Zi-Ke Qin, Yong-Hong Li, Sheng-Jie Guo, Yun-Lin Ye, Fang-Jian Zhou, Wenlin Huang, Ran-Yi Liu & Hui Han

Pages: 2983-2995

Published online: 28 Aug 2018

AbstractforElevated serum LAMC2 is associated with lymph node metastasis and predicts poor prognosis in penile squamous cell carcinoma | Full Text | References | PDF (5.3 MB)

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Article

Distinct prognostic values of mRNA expression of glutathione peroxidases in non-small cell lung cancer

Kui Liu, Meng Jin, Li Xiao, Huiguo Liu & Shuang Wei

Pages: 2997-3005

Published online: 28 Aug 2018

AbstractforDistinct prognostic values of mRNA expression of glutathione peroxidases in non-small cell lung cancer | Full Text | References | PDF (2.7 MB)

96 Views
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Article

A cumulative score based on preoperative fibrinogen and the neutrophil–lymphocyte ratio to predict outcomes in resectable gastric cancer

Xuechao Liu, Zhimin Liu, Enzi Lin, Yingbo Chen, Xiaowei Sun & Zhiwei Zhou

Pages: 3007-3014

Published online: 28 Aug 2018

AbstractforA cumulative score based on preoperative fibrinogen and the neutrophil–lymphocyte ratio to predict outcomes in resectable gastric cancer | Full Text | References | PDF (1 MB)

53 Views
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Article

The predictive value of cumulative toxicity for quality of life in patients with metastatic colorectal cancer during first-line palliative chemotherapy

Claudia SEW Schuurhuizen, Henk MW Verheul, Annemarie MJ Braamse, Laurien M Buffart, Haiko J Bloemendal, Joost Dekker & Inge RHM Konings

Pages: 3015-3021

Published online: 29 Aug 2018

AbstractforThe predictive value of cumulative toxicity for quality of life in patients with metastatic colorectal cancer during first-line palliative chemotherapy | Full Text | References | PDF (160.5 KB)

81 Views
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Article

Prognostic value of aspartate aminotransferase to platelet ratio index as a noninvasive biomarker in patients with hepatocellular carcinoma: a meta-analysis

Yi Zhang & Xu Zhang

Pages: 3023-3032

Published online: 29 Aug 2018

AbstractforPrognostic value of aspartate aminotransferase to platelet ratio index as a noninvasive biomarker in patients with hepatocellular carcinoma: a meta-analysis | Full Text | References | PDF (997.7 KB)

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Review

Review Article

Quantitative assessment of aberrant P16^INK4a methylation in ovarian cancer: a meta-analysis based on literature and TCGA datasets

Jie Ruan, Peipei Xu, Wei Fan, Qiaoling Deng & Mingxia Yu

Pages: 3033-3046

Published online: 29 Aug 2018

AbstractforQuantitative assessment of aberrant P16^INK4a methylation in ovarian cancer: a meta-analysis based on literature and TCGA datasets | Full Text | References | PDF (642.1 KB)

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Original Research

Article

Analysis of potential genes associated with primary cilia in bladder cancer

E Du, Chao Lu, Fei Sheng, Changying Li, Hong Li, Na Ding, Yue Chen, Ting Zhang, Kuo Yang & Yong Xu

Pages: 3047-3056

Published online: 29 Aug 2018

AbstractforAnalysis of potential genes associated with primary cilia in bladder cancer | Full Text | References | PDF (3 MB)

96 Views
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Article

Silencing the expression of copine-III enhances the sensitivity of hepatocellular carcinoma cells to the molecular targeted agent sorafenib

Zhuo Chen, Zhengkui Jiang, Wenzhou Zhang & Baoxia He

Pages: 3057-3067

Published online: 29 Aug 2018

AbstractforSilencing the expression of copine-III enhances the sensitivity of hepatocellular carcinoma cells to the molecular targeted agent sorafenib | Full Text | References | PDF (5.3 MB)

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Article

A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction

Xuanxuan Dai, Junru Zhang, Guilong Guo, Yuepiao Cai, Ri Cui, Changtian Yin, Weidong Liu, Rajamanickam Vinothkumar, Tingting Zhang, Guang Liang & Xiaohua Zhang

Pages: 3069-3082

Published online: 29 Aug 2018

AbstractforA mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction | Full Text | References | PDF (9.3 MB)

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Review

Review Article

Clinical utility of fulvestrant in the treatment of breast cancer: a report on the emerging clinical evidence

Andrea Rocca, Roberta Maltoni, Sara Bravaccini, Caterina Donati & Daniele Andreis

Pages: 3083-3099

Published online: 30 Aug 2018

AbstractforClinical utility of fulvestrant in the treatment of breast cancer: a report on the emerging clinical evidence | Full Text | References | PDF (238.1 KB)

132 Views
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Original Research

Article

Predictive value of carcinoembryonic antigen and carbohydrate antigen 19-9 related to downstaging to stage 0–I after neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Jianyuan Song, Xiaoxue Huang, Zhuhong Chen, Mingqiu Chen, Qingliang Lin, Anchuan Li, Yuangui Chen & Benhua Xu

Pages: 3101-3108

Published online: 30 Aug 2018

AbstractforPredictive value of carcinoembryonic antigen and carbohydrate antigen 19-9 related to downstaging to stage 0–I after neoadjuvant chemoradiotherapy in locally advanced rectal cancer | Full Text | References | PDF (994.2 KB)

48 Views
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Methodology

Article

Probe-based three-dimensional confocal laser endomicroscopy of brain tumors: technical note

Evgenii Belykh, Arpan A Patel, Eric J Miller, Baran Bozkurt, Kaan Yağmurlu, Eric C Woolf, Adrienne C Scheck, Jennifer M Eschbacher, Peter Nakaji & Mark C Preul

Pages: 3109-3123

Published online: 30 Aug 2018

AbstractforProbe-based three-dimensional confocal laser endomicroscopy of brain tumors: technical note | Full Text | References | PDF (17.9 MB)

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Original Research

Article

Prognostic value of serum alkaline phosphatase in the survival of prostate cancer: evidence from a meta-analysis

Dongyang Li, Hang Lv, Xuanyu Hao, Bin Hu & Yongsheng Song

Pages: 3125-3139

Published online: 30 Aug 2018

AbstractforPrognostic value of serum alkaline phosphatase in the survival of prostate cancer: evidence from a meta-analysis | Full Text | References | PDF (1.1 MB)

140 Views
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Article

Association between lncRNA CASC8 polymorphisms and the risk of cancer: a meta-analysis

Zhigang Cui, Min Gao, Zhihua Yin, Lei Yan & Lei Cui

Pages: 3141-3148

Published online: 31 Aug 2018

AbstractforAssociation between lncRNA CASC8 polymorphisms and the risk of cancer: a meta-analysis | Full Text | References | PDF (390.6 KB)

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Article

Methyl jasmonate enhances the radiation sensitivity of esophageal carcinoma cells by inhibiting the 11-ketoprostaglandin reductase activity of AKR1C3

Xiaoying Li, Xin Hong, Xianshu Gao, Xiaobin Gu, Wei Xiong, Jing Zhao, Hongliang Yu, Ming Cui, Mu Xie, Yun Bai & Shaoqian Sun

Pages: 3149-3158

Published online: 31 Aug 2018

AbstractforMethyl jasmonate enhances the radiation sensitivity of esophageal carcinoma cells by inhibiting the 11-ketoprostaglandin reductase activity of AKR1C3 | Full Text | References | PDF (2.9 MB)

54 Views
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Article

ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling

Bin Liu, Xiaojing Xing, Xiang Li, Qianxue Guo, Tonghong Xu & Ke Xu

Pages: 3159-3168

Published online: 03 Sep 2018

AbstractforZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling | Full Text | References | PDF (5.7 MB)

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Article

Prognostic value of tumor burden in nasopharyngeal carcinoma

Chuanben Chen, Zhaodong Fei, Chaoxiong Huang, Jianming Ding & Lisha Chen

Pages: 3169-3175

Published online: 03 Sep 2018

AbstractforPrognostic value of tumor burden in nasopharyngeal carcinoma | Full Text | References | PDF (1.1 MB)

51 Views
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Article

Trend in relative survival in squamous cervical cancer by decade from 1983 to 2012: a period analysis

Jinna Wu, Huanhuan Sun, Shuncong Wang, Yan Yan, Fengze Sun, Yushi Li, Guangwei Yang & Haiqing Ma

Pages: 3177-3191

Published online: 03 Sep 2018

AbstractforTrend in relative survival in squamous cervical cancer by decade from 1983 to 2012: a period analysis | Full Text | References | PDF (2.1 MB)

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Article

Correlation of variable repeat number in the neck regions of DC-SIGN and DC-SIGNR with susceptibility to nasopharyngeal carcinoma in a Chinese population

Sisi Ning, Mengwei Yao, Yuan Wu, Xunzhao Zhou, Changtao Zhong, Kui Yan, Zhengbo Wei & Ying Xie

Pages: 3193-3198

Published online: 04 Sep 2018

AbstractforCorrelation of variable repeat number in the neck regions of DC-SIGN and DC-SIGNR with susceptibility to nasopharyngeal carcinoma in a Chinese population | Full Text | References | PDF (997.7 KB)

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Article

Clinical value of carcinoembryonic antigen for predicting the incidence of brain metastases and survival in small cell lung cancer patients treated with prophylactic cranial irradiation

Dong Guo, Wang Jing, Hui Zhu, Minghuan Li, Bing Zou, Yan Zhang, Lei Fu, Li Kong, Jinbo Yue & Jinming Yu

Pages: 3199-3205

Published online: 04 Sep 2018

AbstractforClinical value of carcinoembryonic antigen for predicting the incidence of brain metastases and survival in small cell lung cancer patients treated with prophylactic cranial irradiation | Full Text | References | PDF (306.2 KB)

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Article

Treatment strategies and predicting prognoses in elderly patients with breast cancer

Zhi Wang, Zhangjian Zhou, Wenxing Li, Wei Wang, Xin Xie, Jincheng Liu, Yongchun Song, Chengxue Dang & Hao Zhang

Pages: 3207-3218

Published online: 04 Sep 2018

AbstractforTreatment strategies and predicting prognoses in elderly patients with breast cancer | Full Text | References | PDF (2.3 MB)

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Article

Surgical intervention may be a therapeutic option for NSCLC patients with AJCC stage IV: a large population-based study

Haiyong Wang, Lei Yan, Cheng Li & Zhehai Wang

Pages: 3219-3226

Published online: 04 Sep 2018

AbstractforSurgical intervention may be a therapeutic option for NSCLC patients with AJCC stage IV: a large population-based study | Full Text | References | PDF (849.9 KB)

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Article

Cervical cancer screening using the Cervista high-risk human papillomavirus test: opportunistic screening of a hospital-based population in Fujian province, China

Guanyu Ruan, Yiyi Song, Binhua Dong, Xiaodan Mao, Fen Lin, Yafang Kang, Shuxia Xu, Xianjing Chen, Qibin Wu & Pengming Sun

Pages: 3227-3235

Published online: 04 Sep 2018

AbstractforCervical cancer screening using the Cervista high-risk human papillomavirus test: opportunistic screening of a hospital-based population in Fujian province, China | Full Text | References | PDF (2.1 MB)

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Article

Prediction of central lymph node metastasis in papillary thyroid microcarcinoma according to clinicopathologic factors and thyroid nodule sonographic features: a case-control study

Wen-Xu Jin, Dan-Rong Ye, Yi-Han Sun, Xiao-Fen Zhou, Ou-Chen Wang, Xiao-Hua Zhang & Ye-Feng Cai

Pages: 3237-3243

Published online: 04 Sep 2018

AbstractforPrediction of central lymph node metastasis in papillary thyroid microcarcinoma according to clinicopathologic factors and thyroid nodule sonographic features: a case-control study | Full Text | References | PDF (156 KB)

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Article

A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer

Ke Xu, Bin Liu, Yegang Ma, Baojin Xu & Xiaojing Xing

Pages: 3245-3254

Published online: 04 Sep 2018

AbstractforA novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer | Full Text | References | PDF (7.4 MB)

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Article

Prognostic value of minichromosome maintenance mRNA expression in early-stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy

Xiwen Liao, Chuangye Han, Xiangkun Wang, Ketuan Huang, Tingdong Yu, Chengkun Yang, Rui Huang, Zhengqian Liu, Quanfa Han & Tao Peng

Pages: 3255-3271

Published online: 05 Sep 2018

AbstractforPrognostic value of minichromosome maintenance mRNA expression in early-stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy | Full Text | References | PDF (9.6 MB)

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Article

Combination of recurrent oral aphthae and dry eye syndrome may constitute an independent risk factor for oral cavity cancer in elderly women

Lei Qin, Yi-Wei Kao, Yueh-Lung Lin, Bou-Yue Peng, Win-Ping Deng, Tsung-Ming Chen, Kuan-Chou Lin, Kevin Sheng-Po Yuan, Alexander TH Wu, Ben-Chang Shia & Szu-Yuan Wu

Pages: 3273-3281

Published online: 05 Sep 2018

AbstractforCombination of recurrent oral aphthae and dry eye syndrome may constitute an independent risk factor for oral cavity cancer in elderly women | Full Text | References | PDF (209.1 KB)

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Article

FOXA1 is upregulated in glioma and promotes proliferation as well as cell cycle through regulation of cyclin D1 expression

Chuanqiang Zhang, Meixia Yang, Yanmin Li, Suwen Tang & Xizhou Sun

Pages: 3283-3293

Published online: 06 Sep 2018

AbstractforFOXA1 is upregulated in glioma and promotes proliferation as well as cell cycle through regulation of cyclin D1 expression | Full Text | References | PDF (2.9 MB)

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Article

Comprehensive analysis of clinical utility of three-dimensional ultrasound for benign and malignant breast masses

Jun Fu, Yanyan Li, Na Li & Zhanzhan Li

Pages: 3295-3303

Published online: 06 Sep 2018

AbstractforComprehensive analysis of clinical utility of three-dimensional ultrasound for benign and malignant breast masses | Full Text | References | PDF (777.3 KB)

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Article

The role of external beam radiotherapy for hepatocellular carcinoma patients with lymph node metastasis: a meta-analysis of observational studies

Chai Hong Rim, Chul Yong Kim, Dae Sik Yang & Won Sup Yoon

Pages: 3305-3315

Published online: 06 Sep 2018

AbstractforThe role of external beam radiotherapy for hepatocellular carcinoma patients with lymph node metastasis: a meta-analysis of observational studies | Full Text | References | PDF (826.9 KB)

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Article

Can bone scans guide therapy with radium-223 dichloride for prostate cancer bone metastases?

Isis Gayed, Vivian Salama, Lydia Dawood, Steven Canfield, David Wan, Chunyan Cai, Usha Joseph & Robert Amato

Pages: 3317-3324

Published online: 07 Sep 2018

AbstractforCan bone scans guide therapy with radium-223 dichloride for prostate cancer bone metastases? | Full Text | References | PDF (1.3 MB)

63 Views
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Article

Musculoskeletal complication in kaposiform hemangioendothelioma without Kasabach–Merritt phenomenon: clinical characteristics and management

Yi Ji, Kaiying Yang, Siyuan Chen, Suhua Peng, Guoyan Lu & Xingtao Liu

Pages: 3325-3331

Published online: 07 Sep 2018

AbstractforMusculoskeletal complication in kaposiform hemangioendothelioma without Kasabach–Merritt phenomenon: clinical characteristics and management | Full Text | References | PDF (1.6 MB)

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Article

Significance of circulating tumor cells in osteosarcoma patients treated by neoadjuvant chemotherapy and surgery

Zhen-Jie Wu, Jia-Chang Tan, Xiong Qin, Bin Liu & Zhen-Chao Yuan

Pages: 3333-3339

Published online: 10 Sep 2018

AbstractforSignificance of circulating tumor cells in osteosarcoma patients treated by neoadjuvant chemotherapy and surgery | Full Text | References | PDF (1.5 MB)

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Article

Associations of sirtuins with clinicopathological parameters and prognosis in non–small cell lung cancer

Jian Gong, Huiyan Wang, Wenwen Lou, Guiye Wang, Hongqun Tao, Huaikai Wen, Yu Liu & Qipeng Xie

Pages: 3341-3356

Published online: 10 Sep 2018

AbstractforAssociations of sirtuins with clinicopathological parameters and prognosis in non–small cell lung cancer | Full Text | References | PDF (5.7 MB)

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Article

RBBP6 expressional effects on cell proliferation and apoptosis in breast cancer cell lines with distinct p53 statuses

Lesetja Raymond Motadi, Mashianoke Marcia Lekganyane & Pontsho Moela

Pages: 3357-3369

Published online: 10 Sep 2018

AbstractforRBBP6 expressional effects on cell proliferation and apoptosis in breast cancer cell lines with distinct p53 statuses | Full Text | References | PDF (8.9 MB)

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Article

The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients

Pengfei Zhang, Meng Zhang, Renfang Han, Kaiping Zhang, Huayang Ding, Chaozhao Liang & Li Zhang

Pages: 3371-3381

Published online: 10 Sep 2018

AbstractforThe correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients | Full Text | References | PDF (2.2 MB)

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Article

Identification of an eight-gene prognostic signature for lung adenocarcinoma

Shicheng Li, Yunpeng Xuan, Bing Gao, Xiao Sun, Shuncheng Miao, Tong Lu, Yuanyong Wang & Wenjie Jiao

Pages: 3383-3392

Published online: 10 Sep 2018

AbstractforIdentification of an eight-gene prognostic signature for lung adenocarcinoma | Full Text | References | PDF (4.4 MB)

200 Views
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Article

Prognostic value of EGFR and KRAS in resected non-small cell lung cancer: a systematic review and meta-analysis

Shi-Ming Zhang, Qing-Ge Zhu, Xiao-Xiao Ding, Song Lin, Jing Zhao, Lei Guan, Ting Li, Bing He & Hu-Qin Zhang

Pages: 3393-3404

Published online: 10 Sep 2018

AbstractforPrognostic value of EGFR and KRAS in resected non-small cell lung cancer: a systematic review and meta-analysis | Full Text | References | PDF (1.1 MB)

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Article

Comparison and validation of the value of preoperative inflammation marker-based prognostic scores in resectable pancreatic ductal adenocarcinoma

Sisi Ye & Li Bai

Pages: 3405-3417

Published online: 11 Sep 2018

AbstractforComparison and validation of the value of preoperative inflammation marker-based prognostic scores in resectable pancreatic ductal adenocarcinoma | Full Text | References | PDF (1.2 MB)

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Article

Checkpoint molecule PD-1-assisted CD8⁺ T lymphocyte count in tumor microenvironment predicts overall survival of patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors

Jiaxi Yao, Wei Xi, Yanjun Zhu, Hang Wang, Xiaoyi Hu & Jianming Guo

Pages: 3419-3431

Published online: 11 Sep 2018

AbstractforCheckpoint molecule PD-1-assisted CD8⁺ T lymphocyte count in tumor microenvironment predicts overall survival of patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors | Full Text | References | PDF (6.8 MB)

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Article

Overexpression of kinesin family member 20A is associated with unfavorable clinical outcome and tumor progression in epithelial ovarian cancer

Han Li, Weijing Zhang, Xiaoying Sun, Jueming Chen, Yue Li, Chunhao Niu, Benke Xu & Yanna Zhang

Pages: 3433-3450

Published online: 12 Sep 2018

AbstractforOverexpression of kinesin family member 20A is associated with unfavorable clinical outcome and tumor progression in epithelial ovarian cancer | Full Text | References | PDF (7.7 MB)

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Article

Assessment of functional variants and expression of long noncoding RNAs in vitamin D receptor signaling in breast cancer

Vahid Kholghi Oskooei, Lobat Geranpayeh, Mir Davood Omrani & Soudeh Ghafouri-Fard

Pages: 3451-3462

Published online: 12 Sep 2018

AbstractforAssessment of functional variants and expression of long noncoding RNAs in vitamin D receptor signaling in breast cancer | Full Text | References | PDF (842.9 KB)

81 Views
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Article

Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer

Nan Wang, Huihui Guo, Zhaohuo Dong, Qiuqiang Chen, Xilin Zhang, Weiyun Shen, Ying Bao & Xiang Wang

Pages: 3463-3471

Published online: 12 Sep 2018

AbstractforEstablishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer | Full Text | References | PDF (2.2 MB)

55 Views
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Article

Splenectomy during cytoreductive surgery in epithelial ovarian cancer

Hengzi Sun, Xiaoning Bi, Dongyan Cao, Jiaxin Yang, Ming Wu, Lingya Pan, Huifang Huang, Ge Chen & Keng Shen

Pages: 3473-3482

Published online: 12 Sep 2018

AbstractforSplenectomy during cytoreductive surgery in epithelial ovarian cancer | Full Text | References | PDF (469.6 KB)

82 Views
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Article

Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity

Daniel J Asby, Clare L Killick-Cole, Lisa J Boulter, William GB Singleton, Claire A Asby, Marcella J Wyatt, Neil U Barua, Alison S Bienemann & Steven S Gill

Pages: 3483-3500

Published online: 12 Sep 2018

AbstractforCombined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity | Full Text | References | PDF (6.4 MB)

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Letter

Letter to the editor “Prognostic value of microRNAs in colorectal cancer: a meta-analysis”

Rama Jayaraj, Chellan Kumarasamy & KM Gothandam

Pages: 3501-3503

Published online: 13 Sep 2018

First Page PreviewforLetter to the editor “Prognostic value of microRNAs in colorectal cancer: a meta-analysis” | Full Text | References | PDF (119.2 KB)

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Original Research

Article

CD8+ tumor-infiltrating lymphocytes as a novel prognostic biomarker in lung sarcomatoid carcinoma, a rare subtype of lung cancer

Jiewei Chen, Qingmei He, Jun Liu, Yongbo Xiao, Canhua Xiao, Keming Chen, Dan Xie & Xinke Zhang

Pages: 3505-3511

Published online: 13 Sep 2018

AbstractforCD8+ tumor-infiltrating lymphocytes as a novel prognostic biomarker in lung sarcomatoid carcinoma, a rare subtype of lung cancer | Full Text | References | PDF (3.4 MB)

74 Views
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Article

Enhanced recovery after surgery decreases intestinal recovery time and pain intensity in patients undergoing curative gastrectomy

Weiping Ji, Arvine Chandoo, Xiaoling Guo, Tao You, Zhuo Shao, Kailian Zheng, Juan Wang, Jianwei Bi, Fang Gao Smith, Olga N Tucker & Xian Shen

Pages: 3513-3520

Published online: 13 Sep 2018

AbstractforEnhanced recovery after surgery decreases intestinal recovery time and pain intensity in patients undergoing curative gastrectomy | Full Text | References | PDF (175.4 KB)

66 Views
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Review

Review Article

Expressions and prognostic values of the E2F transcription factors in human breast carcinoma

Ze-Long Liu, Xi-Wen Bi, Pan-Pan Liu, De-Xin Lei, Yu Wang, Zhi-Ming Li, Wen-Qi Jiang & Yi Xia

Pages: 3521-3532

Published online: 13 Sep 2018

AbstractforExpressions and prognostic values of the E2F transcription factors in human breast carcinoma | Full Text | References | PDF (2.4 MB)

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Original Research

Article

Identification of key candidate genes and small molecule drugs in cervical cancer by bioinformatics strategy

Xin Tang, Yicong Xu, Lin Lu, Yang Jiao, Jianjun Liu, Linlin Wang & Hongbo Zhao

Pages: 3533-3549

Published online: 13 Sep 2018

AbstractforIdentification of key candidate genes and small molecule drugs in cervical cancer by bioinformatics strategy | Full Text | References | PDF (3.4 MB)

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Article

Epidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro

Bo Xie, Liyue Sun, Yanjun Cheng, Juan Zhou, Jihua Zheng & Weimin Zhang

Pages: 3551-3560

Published online: 13 Sep 2018

AbstractforEpidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro | Full Text | References | PDF (5.4 MB)

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Article

PLNR≤20% may be a benefit from PORT for patients with IIIA-N2 NSCLC: a large population-based study

Xiaoling Shang, Zhenxiang Li, Jiamao Lin, Haiyong Wang & Zhehai Wang

Pages: 3561-3567

Published online: 17 Sep 2018

AbstractforPLNR≤20% may be a benefit from PORT for patients with IIIA-N2 NSCLC: a large population-based study | Full Text | References | PDF (735.4 KB)

44 Views
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Article

Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer

Yihao Mao, Qingyang Feng, Peng Zheng, Liangliang Yang, Tianyu Liu, Yuqiu Xu, Dexiang Zhu, Wenju Chang, Meiling Ji, Li Ren, Ye Wei, Guodong He & Jianmin Xu

Pages: 3569-3577

Published online: 17 Sep 2018

AbstractforLow tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer | Full Text | References | PDF (3.3 MB)

110 Views
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Article

miR-300 rs12894467 polymorphism may be associated with susceptibility to primary lung cancer in the Chinese Han population

Zhiqiang Liu, Yong Lin, Shuling Kang, Qiuping Xu, Weimin Xiong, Lin Cai & Fei He

Pages: 3579-3588

Published online: 17 Sep 2018

AbstractformiR-300 rs12894467 polymorphism may be associated with susceptibility to primary lung cancer in the Chinese Han population | Full Text | References | PDF (255.7 KB)

67 Views
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Article

Perivascular cell coverage of intratumoral vasculature is a predictor for bevacizumab efficacy in metastatic colorectal cancer

Chang Jiang, Yu-Hua Huang, Jia-Bin Lu, Yuan-Zhong Yang, Hui-Lan Rao, Bei Zhang, Wen-Zhuo He & Liang-Ping Xia

Pages: 3589-3597

Published online: 17 Sep 2018

AbstractforPerivascular cell coverage of intratumoral vasculature is a predictor for bevacizumab efficacy in metastatic colorectal cancer | Full Text | References | PDF (3.5 MB)

58 Views
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Article

Neutrophil–lymphocyte ratio is a predictor of prognosis in patients with castration-resistant prostate cancer: a meta-analysis

Zhun Wang, Shuanghe Peng, Hui Xie, Linpei Guo, Ning Jiang, Zhiqun Shang & Yuanjie Niu

Pages: 3599-3610

Published online: 17 Sep 2018

AbstractforNeutrophil–lymphocyte ratio is a predictor of prognosis in patients with castration-resistant prostate cancer: a meta-analysis | Full Text | References | PDF (1.5 MB)

63 Views
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Article

Elevated red blood cell distribution width predicts poor prognosis in patients with oral squamous cell carcinoma

Wenzhang Ge, Jianli Xie & Lianzhen Chang

Pages: 3611-3618

Published online: 17 Sep 2018

AbstractforElevated red blood cell distribution width predicts poor prognosis in patients with oral squamous cell carcinoma | Full Text | References | PDF (436.5 KB)

84 Views
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Article

Development of a risk grading system to identify patients with acute promyelocytic leukemia at high risk of early death

Yingmei Zhang, Wenyi Hou, Ping Wang, Jinxiao Hou, HuiyuanYang, Hongli Zhao, Bo Jin, Jiayue Sun, Fenglin Cao, Yanqiu Zhao, Haitao Li, Fei Ge, Jinyue Fu & Jin Zhou

Pages: 3619-3627

Published online: 17 Sep 2018

AbstractforDevelopment of a risk grading system to identify patients with acute promyelocytic leukemia at high risk of early death | Full Text | References | PDF (971.8 KB)

56 Views
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Article

Predictive factors for the efficacy of the second taxane treatment in patients with advanced cancer

Hiroo Imai, Ken Saijo, Keigo Komine, Yoshifumi Kawamura, Sakura Hiraide, Sho Umegaki, Yoshinari Okada, Kota Ohuchi, Yuko Sato, Masahiro Takahashi, Shin Takahashi, Hidekazu Shirota, Masanobu Takahashi & Chikashi Ishioka

Pages: 3629-3636

Published online: 17 Sep 2018

AbstractforPredictive factors for the efficacy of the second taxane treatment in patients with advanced cancer | Full Text | References | PDF (390.7 KB)

60 Views
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Article

Efficacy and safety of lenalidomide for the treatment of acute myeloid leukemia: a systematic review and meta-analysis

Chun-Hong Xie, Min Wei, Fei-Yan Yang, Fu-Zhen Wu, Lei Chen, Jian-Kun Wang, Qin Liu & Jin-Xiong Huang

Pages: 3637-3648

Published online: 18 Sep 2018

AbstractforEfficacy and safety of lenalidomide for the treatment of acute myeloid leukemia: a systematic review and meta-analysis | Full Text | References | PDF (1 MB)

68 Views
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Article

No association between tumor laterality and cardiac-related mortality in breast cancer patients after radiotherapy: a population-based study

Wei-Hua Li, Zi-Guan Zhang, Zheng-Rong Huang, Wei Zhang, Zhi-Bin Li & Zhong-Quan Qi

Pages: 3649-3656

Published online: 18 Sep 2018

AbstractforNo association between tumor laterality and cardiac-related mortality in breast cancer patients after radiotherapy: a population-based study | Full Text | References | PDF (706.9 KB)

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Article

Nomogram predicts survival benefit for non- metastatic esophageal cancer patients who underwent preoperative radiotherapy

Kenan Xie, Song Liu & Jianjun Liu

Pages: 3657-3668

Published online: 18 Sep 2018

AbstractforNomogram predicts survival benefit for non- metastatic esophageal cancer patients who underwent preoperative radiotherapy | Full Text | References | PDF (5.9 MB)

54 Views
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Article

Gemcitabine and docetaxel as second-line chemotherapy in elderly patients with metastatic urothelial carcinoma: a retrospective analysis

Taku Naiki, Keitaro Iida, Toshiki Etani, Takashi Nagai, Yutaro Tanaka, Yosuke Sugiyama, Ryosuke Ando, Shuzo Hamamoto, Rika Banno, Daisuke Nagata, Noriyasu Kawai & Takahiro Yasui

Pages: 3669-3677

Published online: 18 Sep 2018

AbstractforGemcitabine and docetaxel as second-line chemotherapy in elderly patients with metastatic urothelial carcinoma: a retrospective analysis | Full Text | References | PDF (359.4 KB)

44 Views
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Article

Impact of CT slice thickness on volume and dose evaluation during thoracic cancer radiotherapy

Huanli Luo, Yanan He, Fu Jin, Dingyi Yang, Xianfeng Liu, Xueqi Ran & Ying Wang

Pages: 3679-3686

Published online: 20 Sep 2018

AbstractforImpact of CT slice thickness on volume and dose evaluation during thoracic cancer radiotherapy | Full Text | References | PDF (4.1 MB)

80 Views
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Article

Decreased expression of TRIM21 indicates unfavorable outcome and promotes cell growth in breast cancer

Wenbin Zhou, Yayuan Zhang, Caineng Zhong, Jintao Hu, Hong Hu, Dongxian Zhou & MeiQun Cao

Pages: 3687-3696

Published online: 20 Sep 2018

AbstractforDecreased expression of TRIM21 indicates unfavorable outcome and promotes cell growth in breast cancer | Full Text | References | PDF (3.2 MB)

99 Views
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Article

Low expression of VSIG4 is associated with poor prognosis in hepatocellular carcinoma patients with hepatitis B infection

Sicong Zhu, Wenliang Tan, Wenxin Li, Rui Zhou, Xiaolin Wu, Xianqing Chen, Wenda Li, Changzhen Shang & Yajin Chen

Pages: 3697-3705

Published online: 20 Sep 2018

AbstractforLow expression of VSIG4 is associated with poor prognosis in hepatocellular carcinoma patients with hepatitis B infection | Full Text | References | PDF (3 MB)

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Article

A model combining TNM stage and tumor size shows utility in predicting recurrence among patients with hepatocellular carcinoma after resection

Yu Zhang, Shu-wei Chen, Li-li Liu, Xia Yang, Shao-hang Cai & Jing-ping Yun

Pages: 3707-3715

Published online: 20 Sep 2018

AbstractforA model combining TNM stage and tumor size shows utility in predicting recurrence among patients with hepatocellular carcinoma after resection | Full Text | References | PDF (582.3 KB)

53 Views
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Article

An expression signature model to predict lung adenocarcinoma-specific survival

Xiaoshun Shi, Haoming Tan, Xiaobing Le, Haibing Xian, Xiaoxiang Li, Kailing Huang, Viola Yingjun Luo, Yanhui Liu, Zhuolin Wu, Haiyun Mo, Allen M Chen, Ying Liang & Jiexia Zhang

Pages: 3717-3732

Published online: 24 Sep 2018

AbstractforAn expression signature model to predict lung adenocarcinoma-specific survival | Full Text | References | PDF (8.4 MB)

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Review

Review Article

Stereotactic radiosurgery for vestibular schwannomas

Steve Braunstein & Lijun Ma

Pages: 3733-3740

Published online: 20 Sep 2018

AbstractforStereotactic radiosurgery for vestibular schwannomas | Full Text | References | PDF (1.9 MB)

111 Views
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Review Article

Emerging clinical significance of claudin-7 in colorectal cancer: a review

Kun Wang, Chang Xu, Wenjing Li & Lei Ding

Pages: 3741-3752

Published online: 20 Sep 2018

AbstractforEmerging clinical significance of claudin-7 in colorectal cancer: a review | Full Text | References | PDF (563.4 KB)

118 Views
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Original Research

Article

S100A9 regulates cisplatin chemosensitivity of squamous cervical cancer cells and related mechanism

Chuchu Zhao, Ermei Lu, Xiaoli Hu, Huihui Cheng, Jian-An Zhang & Xueqiong Zhu

Pages: 3753-3764

Published online: 20 Sep 2018

AbstractforS100A9 regulates cisplatin chemosensitivity of squamous cervical cancer cells and related mechanism | Full Text | References | PDF (4.4 MB)

99 Views
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Article

The impact of biopsy sampling errors and the quality of surgical margins on local recurrence and survival in chondrosarcoma

Sandro Hodel, Christoph Laux, Jan Farei-Campagna, Tobias Götschi, Beata Bode-Lesniewska & Daniel Andreas Müller

Pages: 3765-3771

Published online: 21 Sep 2018

AbstractforThe impact of biopsy sampling errors and the quality of surgical margins on local recurrence and survival in chondrosarcoma | Full Text | References | PDF (350 KB)

69 Views
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Review

Review Article

Spotlight on cabozantinib for previously untreated advanced renal cell carcinoma: evidence to date

Melissa Bersanelli, Francesco Leonardi & Sebastiano Buti

Pages: 3773-3780

Published online: 21 Sep 2018

AbstractforSpotlight on cabozantinib for previously untreated advanced renal cell carcinoma: evidence to date | Full Text | References | PDF (485.4 KB)

55 Views
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Review Article

Secondhand smoking increases bladder cancer risk in nonsmoking population: a meta-analysis

Huaqing Yan, Yufan Ying, Haiyun Xie, Jiangfeng Li, Xiao Wang, Liujia He, Ke Jin, Jianer Tang, Xin Xu & Xiangyi Zheng

Pages: 3781-3791

Published online: 21 Sep 2018

AbstractforSecondhand smoking increases bladder cancer risk in nonsmoking population: a meta-analysis | Full Text | References | PDF (897.4 KB)

103 Views
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Original Research

Article

Ethylacetate extract from Tetrastigma hemsleyanum inhibits proliferation and induces apoptosis in HepG2 and SMMC-7721 cells

Shipin Chen, Meixiu Luo, Liang Ma & Wenjun Lin

Pages: 3793-3799

Published online: 21 Sep 2018

AbstractforEthylacetate extract from Tetrastigma hemsleyanum inhibits proliferation and induces apoptosis in HepG2 and SMMC-7721 cells | Full Text | References | PDF (1.7 MB)

57 Views
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Article

Polymorphisms in AURKA and AURKB are associated with the survival of triple-negative breast cancer patients treated with taxane-based adjuvant chemotherapy

Yuqian Liao, Yulu Liao, Jun Li, Junyu Li, Ying Fan & Binghe Xu

Pages: 3801-3808

Published online: 21 Sep 2018

AbstractforPolymorphisms in AURKA and AURKB are associated with the survival of triple-negative breast cancer patients treated with taxane-based adjuvant chemotherapy | Full Text | References | PDF (645.5 KB)

92 Views
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Article

Efficacy and safety of de-escalation bone- modifying agents for cancer patients with bone metastases: a systematic review and meta-analysis

Cun Liu, Lu Wang, Lijuan Liu, Jing Zhuang, Shifeng Tang, Tiansong Zhang, Chao Zhou, Fubin Feng, Ruijuan Liu, Jinmei Zhang, Tingting Zhang, Chundi Gao, Huayao Li, Jia Li & Changgang Sun

Pages: 3809-3823

Published online: 21 Sep 2018

AbstractforEfficacy and safety of de-escalation bone- modifying agents for cancer patients with bone metastases: a systematic review and meta-analysis | Full Text | References | PDF (4.5 MB)

62 Views
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Article

Computed tomography scan efficacy in staging gastric linitis plastica lesion: a retrospective multicentric French study

Stéphanie Morgant, Pascal Artru, Ammar Oudjit, Nelson Lourenco, Arnaud Pasquer, Thomas Walter, Jean-Marc Gornet, Alexandre Rouquette, Gérard Lledo, Catherine Brezault & Romain Coriat

Pages: 3825-3831

Published online: 24 Sep 2018

AbstractforComputed tomography scan efficacy in staging gastric linitis plastica lesion: a retrospective multicentric French study | Full Text | References | PDF (1.6 MB)

75 Views
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Article

Multidisciplinary therapy for scirrhous gastric cancer: a retrospective analysis and proposal of new treatment strategy

Sachio Fushida, Jun Kinoshita, Katsunobu Oyama, Takashi Fujimura, Tomoya Tsukada, Takahisa Yamaguchi, Itasu Ninomiya & Tetsuo Ohta

Pages: 3833-3839

Published online: 24 Sep 2018

AbstractforMultidisciplinary therapy for scirrhous gastric cancer: a retrospective analysis and proposal of new treatment strategy | Full Text | References | PDF (469.9 KB)

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Article

Increased derived neutrophil-to-lymphocyte ratio and Breast Imaging-Reporting and Data System classification predict poor survival in patients with non-distant metastatic HER2+ breast cancer treated with neoadjuvant chemotherapy

Yuyong Li, Yi Shao, Lishan Bai & Xingwei Zhou

Pages: 3841-3847

Published online: 24 Sep 2018

AbstractforIncreased derived neutrophil-to-lymphocyte ratio and Breast Imaging-Reporting and Data System classification predict poor survival in patients with non-distant metastatic HER2+ breast cancer treated with neoadjuvant chemotherapy | Full Text | References | PDF (555.3 KB)

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Article

Metabolic syndrome and the risk of cholangiocarcinoma: a hospital-based case–control study in China

Jianping Xiong, Xin Lu, Weiyu Xu, Yi Bai, Hanchun Huang, Jin Bian, Lei Zhang, Junyu Long, Yiyao Xu, Zhenjie Wang & Haitao Zhao

Pages: 3849-3855

Published online: 24 Sep 2018

AbstractforMetabolic syndrome and the risk of cholangiocarcinoma: a hospital-based case–control study in China | Full Text | References | PDF (146.3 KB)

69 Views
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Article

CD44 is overexpressed and correlated with tumor progression in gallbladder cancer

Yuting He, Chen Xue, Yan Yu, Jianan Chen, Xiaolong Chen, Fang Ren, Zhigang Ren, Guangying Cui & Ranran Sun

Pages: 3857-3865

Published online: 24 Sep 2018

AbstractforCD44 is overexpressed and correlated with tumor progression in gallbladder cancer | Full Text | References | PDF (3.1 MB)

99 Views
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Article

Young age increases the risk of lymph node positivity in papillary thyroid cancer patients: a SEER data-based study

Jing Wang, Jianjun Liu, Huayuan Pan, Chenghao Jiang, Song Liu, Zhengzhi Zhu, Jing Fang, Xucai Zheng, Shikai Hong & Shengying Wang

Pages: 3867-3873

Published online: 25 Sep 2018

AbstractforYoung age increases the risk of lymph node positivity in papillary thyroid cancer patients: a SEER data-based study | Full Text | References | PDF (548.3 KB)

72 Views
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Article

Incidence and distribution of advanced colorectal adenomas in patients undergoing colonoscopy for screening, surveillance, and symptoms

Haifeng Kang, Yanmei Yang, Jianwei Qiu, Junbo Qian & Xiaobo Li

Pages: 3875-3880

Published online: 25 Sep 2018

AbstractforIncidence and distribution of advanced colorectal adenomas in patients undergoing colonoscopy for screening, surveillance, and symptoms | Full Text | References | PDF (138.3 KB)

65 Views
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Article

CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p

Shengting Wang, Xukai Xue, Rui Wang, Xiaoming Li, Qian Li, Yufang Wang, Peijun Xie, Yuhua Kang, Rui Meng & Xinghua Feng

Pages: 3881-3890

Published online: 25 Sep 2018

AbstractforCircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p | Full Text | References | PDF (5.2 MB)

90 Views
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Article

First-line treatment strategies for newly diagnosed chronic myeloid leukemia: a network meta-analysis

Kang-Kang Chen, Tai-Feng Du, Ku-Sheng Wu & Wei Yang

Pages: 3891-3910

Published online: 25 Sep 2018

AbstractforFirst-line treatment strategies for newly diagnosed chronic myeloid leukemia: a network meta-analysis | Full Text | References | PDF (2.2 MB)

85 Views
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Article

Prognostic value of the combination of microsatellite instability and BRAF mutation in colorectal cancer

Yingchi Yang, Dong Wang, Lan Jin, Guocong Wu, Zhigang Bai, Jin Wang, Hongwei Yao & Zhongtao Zhang

Pages: 3911-3929

Published online: 26 Sep 2018

AbstractforPrognostic value of the combination of microsatellite instability and BRAF mutation in colorectal cancer | Full Text | References | PDF (4.1 MB)

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Article

Effects of controlled ovarian stimulation on toxicity of TAC chemotherapy in early breast cancer patients

Stefanie de Groot, Leoni A Louwé, Ashna IE Ramautar, Johanneke EA Portielje, Aernout C Ogilvie, Erdogan Batman, Marta Fiocco & Judith R Kroep

Pages: 3931-3935

Published online: 26 Sep 2018

AbstractforEffects of controlled ovarian stimulation on toxicity of TAC chemotherapy in early breast cancer patients | Full Text | References | PDF (132.2 KB)

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Article

KLF6-SV1 is a new prognostic biomarker in postoperative patients with non-small cell lung cancer

Nan Zhang, Zhe Li, Wei Xiao, Fei Yang, Wei Gao & Zhi-Gang Sun

Pages: 3937-3944

Published online: 26 Sep 2018

AbstractforKLF6-SV1 is a new prognostic biomarker in postoperative patients with non-small cell lung cancer | Full Text | References | PDF (2.6 MB)

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Article

Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis

Chenfei Zhou, Xiaojing Feng, Fei Yuan, Jun Ji, Min Shi, Yingyan Yu, Zhenggang Zhu & Jun Zhang

Pages: 3945-3954

Published online: 26 Sep 2018

AbstractforDifference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis | Full Text | References | PDF (3.2 MB)

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Article

Villoglandular adenocarcinoma of cervix: pathologic features, clinical management, and outcome

Peng Guo, Pengfei Liu, Junjun Yang, Tong Ren & Yang Xiang

Pages: 3955-3961

Published online: 26 Sep 2018

AbstractforVilloglandular adenocarcinoma of cervix: pathologic features, clinical management, and outcome | Full Text | References | PDF (158.8 KB)

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Article

Galectin-3 and β-catenin are associated with a poor prognosis in serous epithelial ovarian cancer

Yunyun Liu, Lingling Xie, Dongyan Wang, Da Li, Guocai Xu, Lijuan Wang, Hui Zhou, Yuefei Yu, Zhongqiu Lin & Huaiwu Lu

Pages: 3963-3971

Published online: 26 Sep 2018

AbstractforGalectin-3 and β-catenin are associated with a poor prognosis in serous epithelial ovarian cancer | Full Text | References | PDF (6.1 MB)

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Article

Benefit of adjuvant radiotherapy following narrow-margin hepatectomy in patients with intrahepatic cholangiocarcinoma that adhere to major vessels

Xuan Zheng, Bo Chen, Jian-Xiong Wu, Angela Y Jia, Wei-Qi Rong, Li-Ming Wang, Fan Wu, Yu-Ting Zhao, Ye-Xiong Li & Wei-Hu Wang

Pages: 3973-3981

Published online: 26 Sep 2018

AbstractforBenefit of adjuvant radiotherapy following narrow-margin hepatectomy in patients with intrahepatic cholangiocarcinoma that adhere to major vessels | Full Text | References | PDF (477.8 KB)

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Erratum

Correction

Epidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro [Erratum]

Page: 3983

Published online: 26 Sep 2018

CitationforEpidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro [Erratum] | Full Text | PDF (79.2 KB)

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Original Research

Article

Identification of WDR12 as a novel oncogene involved in hepatocellular carcinoma propagation

Yancun Yin, Ling Zhou, Renhui Zhan, Qiang Zhang & Minjing Li

Pages: 3985-3993

Published online: 27 Sep 2018

AbstractforIdentification of WDR12 as a novel oncogene involved in hepatocellular carcinoma propagation | Full Text | References | PDF (2.8 MB)

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Article

An intronic genetic variation of MGMT affects enhancer activity and is associated with glioma susceptibility

Liming Huang, Wenshen Xu, Lian Dai, Danfang Yan, Shu Zhang & Xi Shi

Pages: 3995-4003

Published online: 27 Sep 2018

AbstractforAn intronic genetic variation of MGMT affects enhancer activity and is associated with glioma susceptibility | Full Text | References | PDF (874 KB)

58 Views
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Article

Young age is an independent adverse prognostic factor in early stage breast cancer: a population-based study

Xiao Zhang, Jian Yang, Haoyang Cai & Yifeng Ye

Pages: 4005-4018

Published online: 27 Sep 2018

AbstractforYoung age is an independent adverse prognostic factor in early stage breast cancer: a population-based study | Full Text | References | PDF (4.2 MB)

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Article

EGFR-TKI-sensitive mutations in lung carcinomas: are they related to clinical features and CT findings?

Xiaoyi Qin, Xiaolong Gu, Yingru Lu & Wei Zhou

Pages: 4019-4027

Published online: 01 Oct 2018

AbstractforEGFR-TKI-sensitive mutations in lung carcinomas: are they related to clinical features and CT findings? | Full Text | References | PDF (1.4 MB)

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Review

Review Article

Role of exosomal small RNA in prostate cancer metastasis

Fei Zhan, Jingling Shen, Ruitao Wang, Liang Wang, Yao Dai, Yanqiao Zhang & Xiaoyi Huang

Pages: 4029-4038

Published online: 28 Sep 2018

AbstractforRole of exosomal small RNA in prostate cancer metastasis | Full Text | References | PDF (1 MB)

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Original Research

Article

Progression and prognostic value of ECT2 in non-small-cell lung cancer and its correlation with PCNA

Xianguang Bai, Ming Yi, Xichao Xia, Shengnan Yu, Xinhua Zheng & Kongming Wu

Pages: 4039-4050

Published online: 28 Sep 2018

AbstractforProgression and prognostic value of ECT2 in non-small-cell lung cancer and its correlation with PCNA | Full Text | References | PDF (6.3 MB)

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Article

Development and validation of an immunity-related classifier of nine chemokines for predicting recurrence in stage I–III patients with colorectal cancer after operation

Guozeng Xu, Yuehan Zhou & Fuxiang Zhou

Pages: 4051-4064

Published online: 01 Oct 2018

AbstractforDevelopment and validation of an immunity-related classifier of nine chemokines for predicting recurrence in stage I–III patients with colorectal cancer after operation | Full Text | References | PDF (2.9 MB)

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Article

Cost-effectiveness analysis of adjuvant treatment for resected pancreatic cancer in China based on the ESPAC-4 trial

Jiaxing Huang, Weiting Liao, Jing Zhou, Pengfei Zhang, Feng Wen, Xinyuan Wang, Mengxi Zhang, Kexun Zhou, Qiuji Wu & Qiu Li

Pages: 4065-4072

Published online: 01 Oct 2018

AbstractforCost-effectiveness analysis of adjuvant treatment for resected pancreatic cancer in China based on the ESPAC-4 trial | Full Text | References | PDF (1,014.9 KB)

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Article

Dietary changes in the first 3 years after breast cancer diagnosis: a prospective Chinese breast cancer cohort study

Yuan-Yuan Lei, Suzanne C Ho, Ashley Cheng, Carol Kwok, Ka Li Cheung, Yi-Qian He, Chi-Kiu Iris Lee, Roselle Lee & Winnie Yeo

Pages: 4073-4084

Published online: 01 Oct 2018

AbstractforDietary changes in the first 3 years after breast cancer diagnosis: a prospective Chinese breast cancer cohort study | Full Text | References | PDF (722.4 KB)

155 Views
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Article

The effect of coping strategy on quality of life in patients with NSCLC

Mariusz Chabowski, Beata Jankowska-Polańska, Katarzyna Lomper & Dariusz Janczak

Pages: 4085-4093

Published online: 01 Oct 2018

AbstractforThe effect of coping strategy on quality of life in patients with NSCLC | Full Text | References | PDF (178.1 KB)

169 Views
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Article

Aspirin use is associated with a reduced risk of cholangiocarcinoma: a systematic review and meta-analysis

Jianping Xiong, Weiyu Xu, Jin Bian, Hanchun Huang, Yi Bai, Yiyao Xu, Xin Lu & Haitao Zhao

Pages: 4095-4104

Published online: 01 Oct 2018

AbstractforAspirin use is associated with a reduced risk of cholangiocarcinoma: a systematic review and meta-analysis | Full Text | References | PDF (489.8 KB)

66 Views
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Article

Locoregional recurrence-associated factors and risk-adapted postmastectomy radiotherapy for breast cancer staged in cT1-2N0-1 after neoadjuvant chemotherapy

Xin Wang, Liming Xu, Zhenzhen Yin, Daquan Wang, Qi Wang, Kunpeng Xu, Jinlin Zhao, Lujun Zhao, Zhiyong Yuan & Ping Wang

Pages: 4105-4112

Published online: 02 Oct 2018

AbstractforLocoregional recurrence-associated factors and risk-adapted postmastectomy radiotherapy for breast cancer staged in cT1-2N0-1 after neoadjuvant chemotherapy | Full Text | References | PDF (611 KB)

60 Views
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Article

Programmed death ligand 1 expression in human intrahepatic cholangiocarcinoma and its association with prognosis and CD8⁺ T-cell immune responses

Ying Zhu, Xiang-Yu Wang, Yu Zhang, Da Xu, Jian Dong, Ze Zhang, Chen-He Yi, Hu-Liang Jia & Xin Yang

Pages: 4113-4123

Published online: 02 Oct 2018

AbstractforProgrammed death ligand 1 expression in human intrahepatic cholangiocarcinoma and its association with prognosis and CD8⁺ T-cell immune responses | Full Text | References | PDF (3.4 MB)

75 Views
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Article

The role of autophagy in the radiosensitivity of the radioresistant human nasopharyngeal carcinoma cell line CNE-2R

Zhong-Guo Liang, Guo-Xiang Lin, Bin-Bin Yu, Fang Su, Ling Li, Song Qu & Xiao-Dong Zhu

Pages: 4125-4134

Published online: 02 Oct 2018

AbstractforThe role of autophagy in the radiosensitivity of the radioresistant human nasopharyngeal carcinoma cell line CNE-2R | Full Text | References | PDF (4.7 MB)

64 Views
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Article

Prognostic value of pre- and post-operative circulating tumor cells detection in colorectal cancer patients treated with curative resection: a prospective cohort study based on ISET device

Chaogang Yang, Dongdong Shi, Shuyi Wang, Chen Wei, Chunxiao Zhang & Bin Xiong

Pages: 4135-4144

Published online: 04 Oct 2018

AbstractforPrognostic value of pre- and post-operative circulating tumor cells detection in colorectal cancer patients treated with curative resection: a prospective cohort study based on ISET device | Full Text | References | PDF (1,004.4 KB)

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Article

A novel gene-pair signature for relapse-free survival prediction in colon cancer

Peng-fei Chen, Fan Wang, Zi-xiong Zhang, Jia-yan Nie, Lan Liu, Jue-rong Feng, Rui Zhou, Hong-ling Wang, Jing Liu & Qiu Zhao

Pages: 4145-4153

Published online: 03 Oct 2018

AbstractforA novel gene-pair signature for relapse-free survival prediction in colon cancer | Full Text | References | PDF (2.4 MB)

85 Views
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Article

MTHFR C677T and A1298C polymorphisms and lung cancer risk in a female Chinese population

Weiwei Tong, Guanghui Tong, Dongyan Jin & Qingjie Lv

Pages: 4155-4161

Published online: 03 Oct 2018

AbstractforMTHFR C677T and A1298C polymorphisms and lung cancer risk in a female Chinese population | Full Text | References | PDF (159 KB)

104 Views
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Review

Review Article

Monitoring of tumor vascular normalization: the key points from basic research to clinical application

Wei Li, Ying-Yao Quan, Yong Li, Ligong Lu & Min Cui

Pages: 4163-4172

Published online: 03 Oct 2018

AbstractforMonitoring of tumor vascular normalization: the key points from basic research to clinical application | Full Text | References | PDF (899.8 KB)

118 Views
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Original Research

Article

Expression of GP88 (progranulin) in serum of prostate cancer patients is associated with Gleason scores and overall survival

Thomas Greither, Kersten Fischer, Gerit Theil, Marios Marcou, Hans-Juergen Holzhausen, Katrin Weigelt, Ginette Serrero, David Hicks, Binbin Yue, Paolo Fornara, Bernd Wullich, Helge Taubert, Sven Wach & Verena Lieb

Pages: 4173-4180

Published online: 05 Oct 2018

AbstractforExpression of GP88 (progranulin) in serum of prostate cancer patients is associated with Gleason scores and overall survival | Full Text | References | PDF (591.4 KB)

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Article

Prognostic factors for postoperative survival among patients with rhabdomyosarcoma of the limbs

Shihong Ren, Zhan Wang, Xin Huang, Lingling Sun, Jinxiang Shao & Zhaoming Ye

Pages: 4181-4189

Published online: 03 Oct 2018

AbstractforPrognostic factors for postoperative survival among patients with rhabdomyosarcoma of the limbs | Full Text | References | PDF (1.2 MB)

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Article

Knockdown of PKM2 suppresses tumor progression in human cervical cancer by modulating epithelial–mesenchymal transition via Wnt/β-catenin signaling

Yanzhu Lin, Fanqing Meng, Zhiyuan Lu, Kai Chen, Yalan Tao, Yi Ouyang & Xinping Cao

Pages: 4191-4202

Published online: 04 Oct 2018

AbstractforKnockdown of PKM2 suppresses tumor progression in human cervical cancer by modulating epithelial–mesenchymal transition via Wnt/β-catenin signaling | Full Text | References | PDF (9 MB)

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Article

Usefulness of plasma D-dimer level for monitoring development of distant organ metastasis in colorectal cancer patients after curative resection

Yi Guo, Feng Chen & Wei Cui

Pages: 4203-4216

Published online: 04 Oct 2018

AbstractforUsefulness of plasma D-dimer level for monitoring development of distant organ metastasis in colorectal cancer patients after curative resection | Full Text | References | PDF (1.7 MB)

56 Views
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Article

IL-17 induces macrophages to M2-like phenotype via NF-κB

Jing Shen, Xin Sun, Bo Pan, Shoubo Cao, Jingyan Cao, Dehai Che, Fang Liu, Shuai Zhang & Yan Yu

Pages: 4217-4228

Published online: 04 Oct 2018

AbstractforIL-17 induces macrophages to M2-like phenotype via NF-κB | Full Text | References | PDF (4.5 MB)

122 Views
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Article

Survival and recurrence patterns of multifocal glioblastoma after radiation therapy

Mustafa Syed, Jakob Liermann, Vivek Verma, Denise Bernhardt, Nina Bougatf, Angela Paul, Stefan Rieken, Jürgen Debus & Sebastian Adeberg

Pages: 4229-4235

Published online: 04 Oct 2018

AbstractforSurvival and recurrence patterns of multifocal glioblastoma after radiation therapy | Full Text | References | PDF (904.6 KB)

105 Views
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Article

Capsaicin-induced TRIB3 upregulation promotes apoptosis in cancer cells

Rong-Jaan Lin, I-Jung Wu, Jo-Yu Hong, Bang-Hung Liu, Ruei-Yue Liang, Tein-Ming Yuan & Show-Mei Chuang

Pages: 4237-4248

Published online: 04 Oct 2018

AbstractforCapsaicin-induced TRIB3 upregulation promotes apoptosis in cancer cells | Full Text | References | PDF (6.3 MB)

94 Views
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Article

Risk factors for delayed chemotherapy-induced nausea and vomiting with low-emetic-risk chemotherapy: a prospective, observational, multicenter study

Toshinobu Hayashi, Mototsugu Shimokawa, Koichi Matsuo, Takanori Miyoshi, Yoko Toriyama, Chiaki Yokota, Jun Taniguchi, Kiyonori Hanada, Kyouichi Tsumagari, Noriko Okubo, Yoshimichi Koutake, Kohei Sakata, Yosei Kawamata, Takashi Goto, Yasufumi Tsurusaki & Makiko Koyabu

Pages: 4249-4255

Published online: 04 Oct 2018

AbstractforRisk factors for delayed chemotherapy-induced nausea and vomiting with low-emetic-risk chemotherapy: a prospective, observational, multicenter study | Full Text | References | PDF (377.6 KB)

105 Views
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Article

lncRNA LOC100132354 promotes angiogenesis through VEGFA/VEGFR2 signaling pathway in lung adenocarcinoma

Yumin Wang, Fan Zhang, Junjun Wang, Lijuan Hu, Feng Jiang, Jian Chen, Jie Chen & Liangxing Wang

Pages: 4257-4266

Published online: 05 Oct 2018

AbstractforlncRNA LOC100132354 promotes angiogenesis through VEGFA/VEGFR2 signaling pathway in lung adenocarcinoma | Full Text | References | PDF (620.5 KB)

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Review

Review Article

Abnormal microRNA expression in the course of hematological malignancies

Agnieszka Szymczyk, Arkadiusz Macheta & Monika Podhorecka

Pages: 4267-4277

Published online: 08 Oct 2018

AbstractforAbnormal microRNA expression in the course of hematological malignancies | Full Text | References | PDF (1 MB)

110 Views
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Original Research

Article

Clinical significance of prognostic score based on age, tumor size, and grade in gastric cancer after gastrectomy

Jingfeng Lu, Yi Chen, Yanxia Liu, Junbin Ding, Zhenhao Piao & Weiyan Liu

Pages: 4279-4286

Published online: 08 Oct 2018

AbstractforClinical significance of prognostic score based on age, tumor size, and grade in gastric cancer after gastrectomy | Full Text | References | PDF (1.2 MB)

59 Views
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Article

Identification of genes and analysis of prognostic values in nonsmoking females with non-small cell lung carcinoma by bioinformatics analyses

Guangda Yang, Qianya Chen, Jieming Xiao, Hailiang Zhang, Zhichao Wang & Xiangan Lin

Pages: 4287-4295

Published online: 08 Oct 2018

AbstractforIdentification of genes and analysis of prognostic values in nonsmoking females with non-small cell lung carcinoma by bioinformatics analyses | Full Text | References | PDF (3.7 MB)

82 Views
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Article

Molecular characterization of papillary thyroid carcinoma: a potential three-lncRNA prognostic signature

Xin You, Sheng Yang, Jing Sui, Wenjuan Wu, Tong Liu, Siyi Xu, Yanping Cheng, Xiaoling Kong, Geyu Liang & Yongzhong Yao

Pages: 4297-4310

Published online: 08 Oct 2018

AbstractforMolecular characterization of papillary thyroid carcinoma: a potential three-lncRNA prognostic signature | Full Text | References | PDF (5.1 MB)

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Article

Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway

Lan Zhang & Weihua Zhang

Pages: 4311-4323

Published online: 08 Oct 2018

AbstractforKnockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway | Full Text | References | PDF (2.6 MB)

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Article

Application of fluorescein sodium in breast cancer brain-metastasis surgery

Shi-yin Xiao, Ji Zhang, Zheng-quan Zhu, You-ping Li, Wei-ying Zhong, Jian-bin Chen, Zhen-yu Pan & Hai-chen Xia

Pages: 4325-4331

Published online: 12 Oct 2018

AbstractforApplication of fluorescein sodium in breast cancer brain-metastasis surgery | Full Text | References | PDF (2.6 MB)

102 Views
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Review

Review Article

Predicting the response to neoadjuvant therapy for early-stage breast cancer: tumor-, blood-, and imaging-related biomarkers

Wenyong Tan, Ming Yang, Hongli Yang, Fangbin Zhou & Weixi Shen

Pages: 4333-4347

Published online: 09 Oct 2018

AbstractforPredicting the response to neoadjuvant therapy for early-stage breast cancer: tumor-, blood-, and imaging-related biomarkers | Full Text | References | PDF (770.1 KB)

133 Views
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Original Research

Article

LIMD1 is a survival prognostic marker of gastric cancer and hinders tumor progression by suppressing activation of YAP1

Di Zhang, Song Li, Wenbin Yu, Cheng Chen, Teng Liu, Yiting Sun, Zeyi Zhao & Lian Liu

Pages: 4349-4361

Published online: 09 Oct 2018

AbstractforLIMD1 is a survival prognostic marker of gastric cancer and hinders tumor progression by suppressing activation of YAP1 | Full Text | References | PDF (6.1 MB)

63 Views
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Article

The high pCR rate of sandwich neoadjuvant treatment in locally advanced rectal cancer may translate into a better long-term survival benefit: 5-year outcome of a Phase II clinical trial

Yong-Hong Hu, Jia-Wang Wei, Hui Chang, Wei-Wei Xiao, Jun-Zhong Lin, Mu-Yan Cai, Pei-Qiang Cai, Ling-Heng Kong, Gong Chen, Zhi-Zhong Pan, Zhi-Fan Zeng, Pei-Rong Ding & Yuan-Hong Gao

Pages: 4363-4369

Published online: 10 Oct 2018

AbstractforThe high pCR rate of sandwich neoadjuvant treatment in locally advanced rectal cancer may translate into a better long-term survival benefit: 5-year outcome of a Phase II clinical trial | Full Text | References | PDF (369.9 KB)

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Article

RETRACTED: Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway

Yan Guo, Hui Zhang, Dalong Xie, Xuanhao Hu, Rongbo Song & Li Zhu

Pages: 4371-4380

Published online: 11 Oct 2018

AbstractforRETRACTED: Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway | PDF (3.6 MB)

15 Views
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Article

Clinicopathological characteristics and treatment outcomes of occult breast cancer: a SEER population-based study

Li-Ping Ge, Xi-Yu Liu, Yi Xiao, Zong-Chao Gou, Shen Zhao, Yi-Zhou Jiang & Gen-Hong Di

Pages: 4381-4391

Published online: 09 Oct 2018

AbstractforClinicopathological characteristics and treatment outcomes of occult breast cancer: a SEER population-based study | Full Text | References | PDF (735.8 KB)

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Article

Serum miR-4530 sensitizes breast cancer to neoadjuvant chemotherapy by suppressing RUNX2

Xiao-Xiao Wang, Fu-Gui Ye, Jie Zhang, Jun-Jing Li, Qing-Xia Chen, Pei-Yang Lin & Chuan-Gui Song

Pages: 4393-4400

Published online: 09 Oct 2018

AbstractforSerum miR-4530 sensitizes breast cancer to neoadjuvant chemotherapy by suppressing RUNX2 | Full Text | References | PDF (653.6 KB)

63 Views
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Article

Importance of tumor size at diagnosis as a prognostic factor for hepatocellular carcinoma survival: a population-based study

Guoyi Wu, Jing Wu, Baohua Wang, Xiaolei Zhu, Xiaolei Shi & Yitao Ding

Pages: 4401-4410

Published online: 10 Oct 2018

AbstractforImportance of tumor size at diagnosis as a prognostic factor for hepatocellular carcinoma survival: a population-based study | Full Text | References | PDF (1.4 MB)

110 Views
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Article

Clinicopathological characteristics and prognostic factors for primary thyroid lymphoma: report on 28 Chinese patients and results of a population-based study

Endong Chen, Qiaolin Wu, Yixiang Jin, Wenxu Jin, Yefeng Cai, Qingxuan Wang, Xiaohua Zhang, Ouchen Wang, Quan Li & Zhouci Zheng

Pages: 4411-4419

Published online: 10 Oct 2018

AbstractforClinicopathological characteristics and prognostic factors for primary thyroid lymphoma: report on 28 Chinese patients and results of a population-based study | Full Text | References | PDF (842.6 KB)

55 Views
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Article

LINE-1 ORF-1p enhances the transcription factor activity of pregnenolone X receptor and promotes sorafenib resistance in hepatocellular carcinoma cells

Yan Chen, Qinglei Zeng, Xiufang Liu, Junliang Fu, Zhen Zeng, Zhiqin Zhao, Ze Liu, Wenlin Bai, Zheng Dong, Hongjin Liu, Xiaoxia Lu, Yunfeng Zhu & Yinying Lu

Pages: 4421-4438

Published online: 10 Oct 2018

AbstractforLINE-1 ORF-1p enhances the transcription factor activity of pregnenolone X receptor and promotes sorafenib resistance in hepatocellular carcinoma cells | Full Text | References | PDF (7.5 MB)

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Article

Response of patients with locally advanced pancreatic adenocarcinoma to high-intensity focused ultrasound treatment: a single-center, prospective, case series in China

Yongshuo Ji, Yu Zhang, Junqiu Zhu, Linglin Zhu, Yanfei Zhu, Kaimeng Hu & Hong Zhao

Pages: 4439-4446

Published online: 09 Oct 2018

AbstractforResponse of patients with locally advanced pancreatic adenocarcinoma to high-intensity focused ultrasound treatment: a single-center, prospective, case series in China | Full Text | References | PDF (862.8 KB)

74 Views
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Article

Confirmed value of shear wave elastography for ultrasound characterization of breast masses using a conservative approach in Chinese women: a large-size prospective multicenter trial

Xi Lin, Cai Chang, Changjun Wu, Qin Chen, Yulan Peng, Baoming Luo, Lina Tang, Jing Li, Jihui Zheng, Ruhai Zhou, Guanghe Cui, Ao Li, Xuemei Wang, Linxue Qian, Jianxing Zhang, Chaoyang Wen, Joel Gay, Huili Zhang, Anhua Li & Yaling Chen

Pages: 4447-4458

Published online: 11 Oct 2018

AbstractforConfirmed value of shear wave elastography for ultrasound characterization of breast masses using a conservative approach in Chinese women: a large-size prospective multicenter trial | Full Text | References | PDF (3.7 MB)

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Article

SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis

Xu Zhang, Peng Zhang, Meng Shao, Xueyan Zang, Jiayin Zhang, Fei Mao, Hui Qian & Wenrong Xu

Pages: 4459-4470

Published online: 10 Oct 2018

AbstractforSALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis | Full Text | References | PDF (6.1 MB)

131 Views
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Article

The effect of intravenous hydration strategy on plasma methotrexate clearance during intravenous high-dose methotrexate administration in pediatric oncology patients

Chanchai Traivaree, Napakjira Likasitthananon, Chalinee Monsereenusorn & Piya Rujkijyanont

Pages: 4471-4478

Published online: 10 Oct 2018

AbstractforThe effect of intravenous hydration strategy on plasma methotrexate clearance during intravenous high-dose methotrexate administration in pediatric oncology patients | Full Text | References | PDF (370.4 KB)

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Article

Clinicopathological characteristics and survival outcomes of bladder neuroendocrine carcinomas: a population-based study

Quan Niu, Youyi Lu, Shigao Xu, Qun Shi, Baoyu Guo, Zhe Guo, Tianbao Huang, Yinxia Wu & Junjie Yu

Pages: 4479-4489

Published online: 11 Oct 2018

AbstractforClinicopathological characteristics and survival outcomes of bladder neuroendocrine carcinomas: a population-based study | Full Text | References | PDF (1.6 MB)

107 Views
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Article

Prognostic values of HE4 expression in patients with cancer: a meta-analysis

Cong Dai, Yi Zheng, Yuanjie Li, Tian Tian, Meng Wang, Peng Xu, Yujiao Deng, Qian Hao, Ying Wu, Zhen Zhai, Zhijun Dai & Jun Lyu

Pages: 4491-4500

Published online: 10 Oct 2018

AbstractforPrognostic values of HE4 expression in patients with cancer: a meta-analysis | Full Text | References | PDF (1.4 MB)

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Review

Review Article

Predictive biomarkers for tumor immune checkpoint blockade

Mengting Tong, Jing Wang, Wenting He, Yanling Wang, Hongming Pan, Da Li & Hongliang Zhang

Pages: 4501-4507

Published online: 11 Oct 2018

AbstractforPredictive biomarkers for tumor immune checkpoint blockade | Full Text | References | PDF (148.7 KB)

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Original Research

Article

Clinicopathologic characteristics and clinical outcomes of pure type and mixed type of tubular carcinoma of the breast: a single-institution cohort study

Wen-Wen Zhang, San-Gang Wu, Yi-Hong Ling, Jia-Yuan Sun, Zhi-Qing Long, Xin Hua, Yong Dong, Feng-Yan Li, Zhen-Yu He & Huan-Xin Lin

Pages: 4509-4515

Published online: 11 Oct 2018

AbstractforClinicopathologic characteristics and clinical outcomes of pure type and mixed type of tubular carcinoma of the breast: a single-institution cohort study | Full Text | References | PDF (417 KB)

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Case Report

Severe toxicity to capecitabine due to a new variant at a donor splicing site in the dihydropyrimidine dehydrogenase (DPYD) gene

Xandra García-González, Sara López-Tarruella, María Isabel García, Eva González-Haba, Carolina Blanco, Sara Salvador-Martin, Yolanda Jerez, Fabienne Thomas, María Jarama, María Sanjurjo Sáez, Miguel Martín & Luis Andrés López-Fernández

Pages: 4517-4522

Published online: 11 Oct 2018

AbstractforSevere toxicity to capecitabine due to a new variant at a donor splicing site in the dihydropyrimidine dehydrogenase (DPYD) gene | Full Text | References | PDF (2.4 MB)

68 Views
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Original Research

Article

Trends in clinical features and survival of oral cavity cancer: fifty years of experience with 3,362 consecutive cases from a single institution

Shu-Wei Chen, Quan Zhang, Zhu-Ming Guo, Wen-Kuan Chen, Wei-Wei Liu, Yan-Feng Chen, Qiu-Li Li, Xue-Kui Liu, Hao Li, Dian Ou-Yang, Wei-Chao Chen, Xiao-Yan Fu, Xi-Di Wang, An-Kui Yang, Jin-Xin Bei & Ming Song

Pages: 4523-4535

Published online: 12 Oct 2018

AbstractforTrends in clinical features and survival of oral cavity cancer: fifty years of experience with 3,362 consecutive cases from a single institution | Full Text | References | PDF (6.5 MB)

160 Views
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Article

Rasip1 is a RUNX1 target gene and promotes migration of NSCLC cells

Yan Chen, Lin Zhang, Lei Liu, Shixiu Sun, Xuyang Zhao, Yueyuan Wang, Yujie Zhang, Jun Du & Luo Gu

Pages: 4537-4552

Published online: 12 Oct 2018

AbstractforRasip1 is a RUNX1 target gene and promotes migration of NSCLC cells | Full Text | References | PDF (8.2 MB)

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Article

RETRACTED ARTICLE: Castleman’s disease in the HIV-endemic setting

Esam-Rajab Mahroug, Candice Sher-Locketz, Minodora-Silvia Desmirean, Emmanuel-Akinola Abayomi, Ciprian Tomuleasa & Ravnit Grewal

Pages: 4553-4563

Published online: 12 Oct 2018

AbstractforRETRACTED ARTICLE: Castleman’s disease in the HIV-endemic setting | PDF (1.7 MB)

21 Views
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Article

Incidence and prognosis factors of extragonadal choriocarcinoma in males: a population-based study

Jingping Qiu, Shi Jia & Guang Li

Pages: 4565-4573

Published online: 15 Oct 2018

AbstractforIncidence and prognosis factors of extragonadal choriocarcinoma in males: a population-based study | Full Text | References | PDF (740.4 KB)

81 Views
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Article

Moderating effects of sleep duration on diabetes risk among cancer survivors: analysis of the National Health Interview Survey in the USA

Azizi A Seixas, Lloyd Gyamfi, Valerie Newsome, Gabrielle Ranger-Murdock, Mark Butler, Diana Margot Rosenthal, Ferdinand Zizi, Irini Youssef, Samy I McFarlane & Girardin Jean-Louis

Pages: 4575-4580

Published online: 12 Oct 2018

AbstractforModerating effects of sleep duration on diabetes risk among cancer survivors: analysis of the National Health Interview Survey in the USA | Full Text | References | PDF (180.3 KB)

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Article

MicroRNA-365 suppresses cell growth and invasion in esophageal squamous cell carcinoma by modulating phosphoserine aminotransferase 1

Changjiang Sun, Xizhi Zhang, Yong Chen, Qingqing Jia, Jianqi Yang & Yusheng Shu

Pages: 4581-4590

Published online: 15 Oct 2018

AbstractforMicroRNA-365 suppresses cell growth and invasion in esophageal squamous cell carcinoma by modulating phosphoserine aminotransferase 1 | Full Text | References | PDF (3.2 MB)

55 Views
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Review

Review Article

The role of biosimilars in value-based oncology care

Kashyap B Patel, Luiz H Arantes Jr, Wing Yu Tang & Selwyn Fung

Pages: 4591-4602

Published online: 17 Oct 2018

AbstractforThe role of biosimilars in value-based oncology care | Full Text | References | PDF (2.2 MB)

147 Views
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Original Research

Article

CAV3.1 knockdown suppresses cell proliferation, migration and invasion of prostate cancer cells by inhibiting AKT

Shanbiao Hu, Ling Li, Wei Huang, Jie Liu, Gongbin Lan, Shaojie Yu, Longkai Peng, Xubiao Xie, Luoyan Yang, Yeqi Nian & Yinhuai Wang

Pages: 4603-4614

Published online: 15 Oct 2018

AbstractforCAV3.1 knockdown suppresses cell proliferation, migration and invasion of prostate cancer cells by inhibiting AKT | Full Text | References | PDF (8.5 MB)

71 Views
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Article

DJ-1 promotes survival of human colon cancer cells under hypoxia by modulating HIF-1α expression through the PI3K-AKT pathway

Hong Zheng, Chao Zhou, Xiao Lu, Quanxing Liu, Minqiang Liu, Guoqing Chen, Weigang Chen, Shuai Wang & Yuan Qiu

Pages: 4615-4629

Published online: 16 Oct 2018

AbstractforDJ-1 promotes survival of human colon cancer cells under hypoxia by modulating HIF-1α expression through the PI3K-AKT pathway | Full Text | References | PDF (2.8 MB)

70 Views
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Review

Review Article

Advances in antitumor effects of NSAIDs

Zhen Zhang, Fulin Chen & Lijun Shang

Pages: 4631-4640

Published online: 15 Oct 2018

AbstractforAdvances in antitumor effects of NSAIDs | Full Text | References | PDF (172 KB)

234 Views
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Original Research

Article

Long noncoding RNA ROR as a novel biomarker for progress and prognosis outcome in human cancer: a meta-analysis in the Asian population

Shengquan Yang, Jian Chen, Yang Yu, Deli Li, Mengyuan Huang, Li Yuan & Guoyong Yin

Pages: 4641-4652

Published online: 15 Oct 2018

AbstractforLong noncoding RNA ROR as a novel biomarker for progress and prognosis outcome in human cancer: a meta-analysis in the Asian population | Full Text | References | PDF (618.8 KB)

51 Views
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Review

Review Article

Celecoxib in breast cancer prevention and therapy

Jieqing Li, Qiongyu Hao, Wei Cao, Jaydutt V Vadgama & Yong Wu

Pages: 4653-4667

Published online: 26 Oct 2018

AbstractforCelecoxib in breast cancer prevention and therapy | Full Text | References | PDF (593 KB)

252 Views
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Letter

Systematic review and meta-analysis of cancer studies evaluating diagnostic test accuracy and prognostic values: approaches to improve clinical interpretation of results

Rama Jayaraj & Chellan Kumarasamy

Pages: 4669-4670

Published online: 16 Oct 2018

CitationforSystematic review and meta-analysis of cancer studies evaluating diagnostic test accuracy and prognostic values: approaches to improve clinical interpretation of results | Full Text | References | PDF (118.4 KB)

87 Views
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Original Research

Article

Preoperative PROSTATE scoring system: a potential predictive tool for the risk of biochemical recurrence after radical prostatectomy

Zhe-Nan Zhang, Cheng Luo, Ben Xu, Hai-Feng Song, Bing-Lei Ma & Qian Zhang

Pages: 4671-4677

Published online: 16 Oct 2018

AbstractforPreoperative PROSTATE scoring system: a potential predictive tool for the risk of biochemical recurrence after radical prostatectomy | Full Text | References | PDF (178.9 KB)

46 Views
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Article

Impact of tumor dimensions and lymph node density on the survival of patients with hypopharyngeal squamous cell carcinoma

Lu-Lu Ye, Jia Rao, Xing-Wen Fan, Qing-Hai Ji, Chao-Su Hu & Hong-Mei Ying

Pages: 4679-4688

Published online: 18 Oct 2018

AbstractforImpact of tumor dimensions and lymph node density on the survival of patients with hypopharyngeal squamous cell carcinoma | Full Text | References | PDF (677.8 KB)

60 Views
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Case Report

An ioMRI-assisted case of cervical intramedullary diffuse glioma resection

Zafer Orkun Toktas, Baran Yilmaz, Murat Şakir Ekşi, Lei Wang, Akin Akakin, Yasin Yener, Murat Konakcı, Emre Ayan, Turker Kılıc, Deniz Konya & Yang D Teng

Pages: 4689-4694

Published online: 17 Oct 2018

AbstractforAn ioMRI-assisted case of cervical intramedullary diffuse glioma resection | Full Text | References | PDF (2.8 MB)

60 Views
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Original Research

Article

Preoperative albumin-to-globulin ratio as a significant prognostic indicator in urologic cancers: a meta-analysis

Yi Zhang, Lijuan Wang, Shibu Lin & Rong Wang

Pages: 4695-4708

Published online: 17 Oct 2018

AbstractforPreoperative albumin-to-globulin ratio as a significant prognostic indicator in urologic cancers: a meta-analysis | Full Text | References | PDF (1.4 MB)

52 Views
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Article

Impact of the new FIGO 2013 classification on prognosis of stage I epithelial ovarian cancers

Céline Montavon Sartorius, Uzma Mirza, Andreas Schötzau, Gillian Mackay, Daniel Fink, Neville F Hacker & Viola Heinzelmann-Schwarz

Pages: 4709-4718

Published online: 17 Oct 2018

AbstractforImpact of the new FIGO 2013 classification on prognosis of stage I epithelial ovarian cancers | Full Text | References | PDF (574.4 KB)

66 Views
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Article

Transarterial chemoembolization for hepatocellular carcinoma combined with portal vein tumor thrombosis

Wei-Fu Lv, Kai-Cai Liu, Dong Lu, Chun-Ze Zhou, De-Lei Cheng, Jing-Kun Xiao, Xing-Ming Zhang & Zheng-Feng Zhang

Pages: 4719-4726

Published online: 17 Oct 2018

AbstractforTransarterial chemoembolization for hepatocellular carcinoma combined with portal vein tumor thrombosis | Full Text | References | PDF (459 KB)

76 Views
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Article

Prognostic significance of pretreatment lymphocyte/monocyte ratio in retroperitoneal liposarcoma patients after radical resection

Peng Luo, Weiluo Cai, Lingge Yang, Shiqi Chen, Zhiqiang Wu, Yong Chen, Ruming Zhang, Yingqiang Shi, Wangjun Yan & Chunmeng Wang

Pages: 4727-4734

Published online: 18 Oct 2018

AbstractforPrognostic significance of pretreatment lymphocyte/monocyte ratio in retroperitoneal liposarcoma patients after radical resection | Full Text | References | PDF (420.5 KB)

49 Views
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Article

miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins

Yanqin Sun, Bingshuang Hu, Yanhong Wang, Zhen Li, Jingfang Wu, Yunchu Yang, Yue Wei, Xiaofeng Peng, Hongling Chen, Rongqi Chen, Pingyan Jiang, Sixian Fang, Zhiwu Yu & Linlang Guo

Pages: 4735-4745

Published online: 18 Oct 2018

AbstractformiR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins | Full Text | References | PDF (4 MB)

83 Views
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Article

Identification of chemoresistance-associated miRNAs in breast cancer

Weiyang Lou, Jingxing Liu, Bisha Ding, Liang Xu & Weimin Fan

Pages: 4747-4757

Published online: 23 Oct 2018

AbstractforIdentification of chemoresistance-associated miRNAs in breast cancer | Full Text | References | PDF (3.7 MB)

151 Views
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Article

Palliative gastrectomy plus chemotherapy versus chemotherapy alone for incurable advanced gastric cancer: a meta-analysis

Pei Wu, Pengliang Wang, Bin Ma, Songcheng Yin, Yuen Tan, Wenbin Hou, Zhenning Wang, Huimian Xu & Zhi Zhu

Pages: 4759-4771

Published online: 26 Oct 2018

AbstractforPalliative gastrectomy plus chemotherapy versus chemotherapy alone for incurable advanced gastric cancer: a meta-analysis | Full Text | References | PDF (994.4 KB)

91 Views
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Article

The novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin

Xiaonan Wang, Jing Tian, Xue Jiao, Jin Geng, Reizhe Wang, Ning Liu, Xinghua Gao, Noreen Griffin, Yuan Gao & Fengping Shan

Pages: 4773-4787

Published online: 18 Oct 2018

AbstractforThe novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin | Full Text | References | PDF (9 MB)

69 Views
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Article

Preoperative C-reactive protein/albumin ratio is a significant predictor of survival in bladder cancer patients after radical cystectomy: a retrospective study

Yadong Guo, Keke Cai, Shiyu Mao, Junfeng Zhang, Longsheng Wang, Ziwei Zhang, Mengnan Liu, Wentao Zhang, Yuan Wu, Yang Yan & Xudong Yao

Pages: 4789-4804

Published online: 23 Oct 2018

AbstractforPreoperative C-reactive protein/albumin ratio is a significant predictor of survival in bladder cancer patients after radical cystectomy: a retrospective study | Full Text | References | PDF (1.9 MB)

62 Views
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Article

Xiaofei Zhu, Fuqi Li, Dongchen Shi, Xiaoping Ju, Yangsen Cao, Yuxin Shen, Fei Cao, Shuiwang Qing, Fang Fang, Zhen Jia & Huojun Zhang

Pages: 4805-4815

Published online: 23 Oct 2018

AbstractforHealth-related quality of life for gemcitabine and nab-paclitaxel plus radiotherapy versus gemcitabine and S-1 plus radiotherapy in patients with metastatic pancreatic cancer | Full Text | References | PDF (637 KB)

56 Views
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Article

Clofoctol and sorafenib inhibit prostate cancer growth via synergistic induction of endoplasmic reticulum stress and UPR pathways

Lixia Fan, Zhenglei He, Sarah A Head, Yinghui Zhou, Ting Lu, Xulong Feng, Xueqing Zhang, Meng Zhang, Yongjun Dang, Xinghong Jiang & Minghua Wang

Pages: 4817-4829

Published online: 23 Oct 2018

AbstractforClofoctol and sorafenib inhibit prostate cancer growth via synergistic induction of endoplasmic reticulum stress and UPR pathways | Full Text | References | PDF (4 MB)

94 Views
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Article

Comparison of the effects of stellate ganglion block and paroxetine on hot flashes and sleep disturbance in breast cancer survivors

Poupak Rahimzadeh, Farnad Imani, Nahid Nafissi, Behzad Ebrahimi & Seyed Hamid Reza Faiz

Pages: 4831-4837

Published online: 26 Oct 2018

AbstractforComparison of the effects of stellate ganglion block and paroxetine on hot flashes and sleep disturbance in breast cancer survivors | Full Text | References | PDF (751.9 KB)

80 Views
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Article

Type-specific high-risk human papillomavirus viral load as a viable triage indicator for high-grade squamous intraepithelial lesion: a nested case– control study

Binhua Dong, Pengming Sun, Guanyu Ruan, Weiyi Huang, Xiaodan Mao, Yafang Kang, Diling Pan & Fen Lin

Pages: 4839-4851

Published online: 23 Oct 2018

AbstractforType-specific high-risk human papillomavirus viral load as a viable triage indicator for high-grade squamous intraepithelial lesion: a nested case– control study | Full Text | References | PDF (2.1 MB)

101 Views
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Review

Review Article

Dosimetric evaluation and systematic review of radiation therapy techniques for early stage node-negative breast cancer treatment

Tabitha Y Chan, Johann I Tang, Poh Wee Tan & Neill Roberts

Pages: 4853-4870

Published online: 23 Oct 2018

AbstractforDosimetric evaluation and systematic review of radiation therapy techniques for early stage node-negative breast cancer treatment | Full Text | References | PDF (278.5 KB)

104 Views
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Original Research

Article

CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value

Bo Xu, Tieyi Yang, Zhi Wang, Yan Zhang, Shuyi Liu & Mingquan Shen

Pages: 4871-4880

Published online: 23 Oct 2018

AbstractforCircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value | Full Text | References | PDF (4.7 MB)

124 Views
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Review

Review Article

Effects of metformin treatment on radiotherapy efficacy in patients with cancer and diabetes: a systematic review and meta-analysis

Mingyue Rao, Chenlin Gao, Man Guo, Betty Yuen Kwan Law & Yong Xu

Pages: 4881-4890

Published online: 24 Oct 2018

AbstractforEffects of metformin treatment on radiotherapy efficacy in patients with cancer and diabetes: a systematic review and meta-analysis | Full Text | References | PDF (1.7 MB)

122 Views
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Original Research

Article

Prognostic role of derived neutrophil-to-lymphocyte ratio in surgical triple-negative breast cancer

Kuojun Ren, Yachao Yin, Fang He, Yi Shao & Shengying Wang

Pages: 4891-4898

Published online: 24 Oct 2018

AbstractforPrognostic role of derived neutrophil-to-lymphocyte ratio in surgical triple-negative breast cancer | Full Text | References | PDF (249 KB)

56 Views
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Article

The fluctuating incidence, improved survival of patients with breast cancer, and disparities by age, race, and socioeconomic status by decade, 1981–2010

Guanming Lu, Jie Li, Shuncong Wang, Jian Pu, Huanhuan Sun, Zhongheng Wei, Yanfei Ma, Jun Wang & Haiqing Ma

Pages: 4899-4914

Published online: 30 Oct 2018

AbstractforThe fluctuating incidence, improved survival of patients with breast cancer, and disparities by age, race, and socioeconomic status by decade, 1981–2010 | Full Text | References | PDF (2.2 MB)

82 Views
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Article

Clinicopathological and survival analysis of uterine papillary serous carcinoma: a single institutional review of 106 cases

Yao Wang, Mei Yu, Jia-Xin Yang, Dong-Yan Cao, Keng Shen & Jing-He Lang

Pages: 4915-4928

Published online: 25 Oct 2018

AbstractforClinicopathological and survival analysis of uterine papillary serous carcinoma: a single institutional review of 106 cases | Full Text | References | PDF (311.2 KB)

70 Views
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Article

Microscopic hematuria predicts lower stage in patients with upper tract urothelial carcinoma

Nienie Qi, Jiufeng Zhang, Yue Chen, Rumin Wen & Hailong Li

Pages: 4929-4933

Published online: 24 Oct 2018

AbstractforMicroscopic hematuria predicts lower stage in patients with upper tract urothelial carcinoma | Full Text | References | PDF (133.3 KB)

90 Views
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Article

Sarcopenia is associated with the neutrophil/lymphocyte and platelet/lymphocyte ratios in operable gastric cancer patients: a prospective study

Ji Lin, Weiteng Zhang, Yunshi Huang, Weisheng Chen, Ruisen Wu, Xiaodong Chen, Neng Lou & Pengfei Wang

Pages: 4935-4944

Published online: 25 Oct 2018

AbstractforSarcopenia is associated with the neutrophil/lymphocyte and platelet/lymphocyte ratios in operable gastric cancer patients: a prospective study | Full Text | References | PDF (210.2 KB)

91 Views
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Article

Exosomes derived from rAAV/AFP-transfected dendritic cells elicit specific T cell-mediated immune responses against hepatocellular carcinoma

Jieyu Li, Shenglan Huang, Zhifeng Zhou, Wansong Lin, Shuping Chen, Mingshui Chen & Yunbin Ye

Pages: 4945-4957

Published online: 29 Oct 2018

AbstractforExosomes derived from rAAV/AFP-transfected dendritic cells elicit specific T cell-mediated immune responses against hepatocellular carcinoma | Full Text | References | PDF (4.8 MB)

94 Views
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Article

The association of XRCC1 polymorphism with osteosarcoma risk, clinicopathologic features, and prognosis in a Chinese Han population

Ying-Guang Wu, Hong-Fu Li, Yan-Jun Ren, De-Bo Zou, Kai-Ning Zhang & Xing Xiao

Pages: 4959-4967

Published online: 25 Oct 2018

AbstractforThe association of XRCC1 polymorphism with osteosarcoma risk, clinicopathologic features, and prognosis in a Chinese Han population | Full Text | References | PDF (532.3 KB)

52 Views
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Article

Higher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer

Yu-Teng Ma, Xiao-Fang Xing, Bin Dong, Xiao-Jing Cheng, Ting Guo, Hong Du, Xian-Zi Wen & Jia-Fu Ji

Pages: 4969-4980

Published online: 25 Oct 2018

AbstractforHigher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer | Full Text | References | PDF (4.3 MB)

82 Views
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Article

Improving risk prediction for pancreatic cancer in symptomatic patients: a Saudi Arabian study

Anwar E Ahmed, Faris S Alzahrani, Ahmed M Gharawi, Salman A Alammary, Fahad H Almijmaj, Fahad M Alhusayni, Donna K McClish, Hamdan Al-Jahdali, Ashwaq A Al Olayan & Abdul Rahman Jazieh

Pages: 4981-4986

Published online: 25 Oct 2018

AbstractforImproving risk prediction for pancreatic cancer in symptomatic patients: a Saudi Arabian study | Full Text | References | PDF (213.3 KB)

92 Views
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Review

Review Article

Contrast-enhanced ultrasound for the differential diagnosis between benign and metastatic superficial lymph nodes: a meta-analysis

Mei Mei, Ligang Ye, Juan Quan & Pintong Huang

Pages: 4987-4997

Published online: 26 Oct 2018

AbstractforContrast-enhanced ultrasound for the differential diagnosis between benign and metastatic superficial lymph nodes: a meta-analysis | Full Text | References | PDF (1.8 MB)

79 Views
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Original Research

Article

Overexpression of lncRNA PANDAR predicts adverse prognosis in acute myeloid leukemia

Lan Yang, Jing-Dong Zhou, Ting-Juan Zhang, Ji-Chun Ma, Gao-Fei Xiao, Qin Chen, Zhao-Qun Deng, Jiang Lin, Jun Qian & Dong-Ming Yao

Pages: 4999-5007

Published online: 29 Oct 2018

AbstractforOverexpression of lncRNA PANDAR predicts adverse prognosis in acute myeloid leukemia | Full Text | References | PDF (1.1 MB)

118 Views
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Article

Calcium channel α2δ1 subunit (CACNA2D1) enhances radioresistance in cancer stem-like cells in non-small cell lung cancer cell lines

Xin Sui, Jian-Hao Geng, Yong-Heng Li, Guang-Ying Zhu & Wei-Hu Wang

Pages: 5009-5018

Published online: 26 Oct 2018

AbstractforCalcium channel α2δ1 subunit (CACNA2D1) enhances radioresistance in cancer stem-like cells in non-small cell lung cancer cell lines | Full Text | References | PDF (5.5 MB)

119 Views
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Article

Peroxiredoxin 1 silencing inhibited the growth and promoted apoptosis of pancreatic cancer cells via targeting FOXO3 gene

Xianchun Sun, Lingting Kong, Bingshu Li, Yan Zhang & Haiyan Yang

Pages: 5019-5026

Published online: 26 Oct 2018

AbstractforPeroxiredoxin 1 silencing inhibited the growth and promoted apoptosis of pancreatic cancer cells via targeting FOXO3 gene | Full Text | References | PDF (2.2 MB)

53 Views
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Review

Review Article

Prognostic value of plasma fibrinogen in hepatocellular carcinoma: a meta-analysis

Guanqun Huang, Hui Jiang, Ye Lin, Yanpeng Wu, Weilong Cai, Boyun Shi, Yuanwei Luo, Zhixiang Jian & Xinke Zhou

Pages: 5027-5041

Published online: 29 Oct 2018

AbstractforPrognostic value of plasma fibrinogen in hepatocellular carcinoma: a meta-analysis | Full Text | References | PDF (1.2 MB)

78 Views
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Original Research

Article

NSAID consumption and risk of acute myeloid leukemia: a national population-based case-control study

Lene Sofie Granfeldt Østgård, Mette Nørgaard, Lars Pedersen, René Østgård, Lone Smidstrup Friis, Claudia Schöllkopf, Marianne Tang Severinsen, Claus Werenberg Marcher, Bruno C Medeiros & Morten Krogh Jensen

Pages: 5043-5051

Published online: 29 Oct 2018

AbstractforNSAID consumption and risk of acute myeloid leukemia: a national population-based case-control study | Full Text | References | PDF (162.2 KB)

81 Views
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Article

Hypofractionated postoperative helical tomotherapy in prostate cancer: a mono-institutional report of toxicity and clinical outcomes

Francesco Cuccia, Gianluca Mortellaro, Vincenzo Serretta, Vito Valenti, Antonella Tripoli, Marina Gueci, Nicoletta Luca, Antonio Lo Casto & Giuseppe Ferrera

Pages: 5053-5060

Published online: 29 Oct 2018

AbstractforHypofractionated postoperative helical tomotherapy in prostate cancer: a mono-institutional report of toxicity and clinical outcomes | Full Text | References | PDF (658.6 KB)

57 Views
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Article

Pegaspargase, gemcitabine, dexamethasone, and cisplatin (P-GDP) combined chemotherapy is effective for newly diagnosed extranodal NK/T-cell lymphoma: a retrospective study

Tao Liu, Fang Zhu, Yin Xiao, Qiuhui Li, Xinxiu Liu, Kunyu Yang, Gang Wu & Liling Zhang

Pages: 5061-5069

Published online: 29 Oct 2018

AbstractforPegaspargase, gemcitabine, dexamethasone, and cisplatin (P-GDP) combined chemotherapy is effective for newly diagnosed extranodal NK/T-cell lymphoma: a retrospective study | Full Text | References | PDF (465.5 KB)

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Article

Knockdown of PRL-3 increases mitochondrial superoxide anion production through transcriptional regulation of RAP1

Yongyong Yang, Shenyi Lian, Lin Meng, Zhihua Tian, Qin Feng, Yue Wang, Ping Wang, Like Qu & Chengchao Shou

Pages: 5071-5081

Published online: 30 Oct 2018

AbstractforKnockdown of PRL-3 increases mitochondrial superoxide anion production through transcriptional regulation of RAP1 | Full Text | References | PDF (4.2 MB)

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Article

Elevated DKK1 expression is an independent unfavorable prognostic indicator of survival in head and neck squamous cell carcinoma

Haihe Gao, Lisha Li, Mang Xiao, Yongwei Guo, Yi Shen, Lixin Cheng & Ming Tang

Pages: 5083-5089

Published online: 30 Oct 2018

AbstractforElevated DKK1 expression is an independent unfavorable prognostic indicator of survival in head and neck squamous cell carcinoma | Full Text | References | PDF (589.5 KB)

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Article

NKAP functions as an oncogene and its expression is induced by CoCl₂ treatment in breast cancer via AKT/mTOR signaling pathway

Jiangtao Liu, Honghui Wang, Yanhai Yin, Qing Li & Mei Zhang

Pages: 5091-5100

Published online: 29 Oct 2018

AbstractforNKAP functions as an oncogene and its expression is induced by CoCl₂ treatment in breast cancer via AKT/mTOR signaling pathway | Full Text | References | PDF (4.8 MB)

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Article

RETRACTED ARTICLE: Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer

Chen Xue, Yuting He, Qiuyue Hu, Yan Yu, Xiaolong Chen, Jianan Chen, Fang Ren, Juan Li, Zhigang Ren, Guangying Cui & Ranran Sun

Pages: 5101-5112

Published online: 30 Oct 2018

AbstractforRETRACTED ARTICLE: Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer | PDF (7.2 MB)

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Article

CCNA2 acts as a novel biomarker in regulating the growth and apoptosis of colorectal cancer

Yaqi Gan, Yimin Li, Tong Li, Guang Shu & Gang Yin

Pages: 5113-5124

Published online: 31 Oct 2018

AbstractforCCNA2 acts as a novel biomarker in regulating the growth and apoptosis of colorectal cancer | Full Text | References | PDF (3.8 MB)

145 Views
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Article

Behavior change techniques for increasing physical activity in cancer survivors: a systematic review and meta-analysis of randomized controlled trials

Emily Finne, Melanie Glausch, Anne-Kathrin Exner, Odile Sauzet, Friederike Stölzel & Nadja Seidel

Pages: 5125-5143

Published online: 30 Oct 2018

AbstractforBehavior change techniques for increasing physical activity in cancer survivors: a systematic review and meta-analysis of randomized controlled trials | Full Text | References | PDF (566.9 KB)

624 Views
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Article

Downregulation of FOXO6 in breast cancer promotes epithelial–mesenchymal transition and facilitates migration and proliferation of cancer cells

Hui Ye & Meiling Duan

Pages: 5145-5156

Published online: 30 Oct 2018

AbstractforDownregulation of FOXO6 in breast cancer promotes epithelial–mesenchymal transition and facilitates migration and proliferation of cancer cells | Full Text | References | PDF (4.4 MB)

67 Views
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Article

Laparoscopic right hemicolectomy oriented by superior mesenteric artery for right colon cancer: efficacy evaluation with a match-controlled analysis

Weigang Dai, Jian Zhang, Weixin Xiong, Jianbo Xu, Shirong Cai, Min Tan, Yulong He, Wu Song & Yujie Yuan

Pages: 5157-5170

Published online: 30 Oct 2018

AbstractforLaparoscopic right hemicolectomy oriented by superior mesenteric artery for right colon cancer: efficacy evaluation with a match-controlled analysis | Full Text | References | PDF (4 MB)

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Article

RETRACTED ARTICLE: MicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells

Chunfang Wang, Ke Su, Yanyan Zhang, Weiwei Zhang, Danxia Chu, Qian Zhao & Ruixia Guo

Pages: 5171-5185

Published online: 30 Oct 2018

AbstractforRETRACTED ARTICLE: MicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells | PDF (3.9 MB)

16 Views
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Article

MicroRNA-588 regulates invasion, migration and epithelial–mesenchymal transition via targeting EIF5A2 pathway in gastric cancer

Xiaorong Zhou, Manli Xu, Yonghong Guo, Ling Ye, Limin Long, Haiqin Wang, Pan Tan & Meili Xu

Pages: 5187-5197

Published online: 30 Oct 2018

AbstractforMicroRNA-588 regulates invasion, migration and epithelial–mesenchymal transition via targeting EIF5A2 pathway in gastric cancer | Full Text | References | PDF (5.5 MB)

55 Views
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Article

Interleukin-18 promoter genotype is associated with the risk of nasopharyngeal carcinoma in Taiwan

Chung-Yu Huang, Wen-Shin Chang, Chia-Wen Tsai, Te-Chun Hsia, Te-Chun Shen, Da-Tian Bau & Hao-Ai Shui

Pages: 5199-5207

Published online: 31 Oct 2018

AbstractforInterleukin-18 promoter genotype is associated with the risk of nasopharyngeal carcinoma in Taiwan | Full Text | References | PDF (195.3 KB)

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Article

Genetic variants in lncRNA HOTAIR are associated with lung cancer susceptibility in a Chinese Han population in China: a case–control study

Hang Li, Zitai Yang, Juan Li, Xiaoting Lv, Min Gao, Yanhong Bi, Ziwei Zhang, Shengli Wang, Sixuan Li, Na Li, Zhigang Cui, Baosen Zhou & Zhihua Yin

Pages: 5209-5218

Published online: 31 Oct 2018

AbstractforGenetic variants in lncRNA HOTAIR are associated with lung cancer susceptibility in a Chinese Han population in China: a case–control study | Full Text | References | PDF (535.7 KB)

67 Views
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Article

ypTNM category combined with AJCC tumor regression grade for screening patients with the worst prognosis after neoadjuvant chemoradiation therapy for locally advanced rectal cancer

Jiawang Wei, Rong Huang, Suping Guo, Xuhui Zhang, Shaoyan Xi, Qiaoxuan Wang, Hui Chang, Xiaohao Wang, Weiwei Xiao, Zhifan Zeng & Yuanhong Gao

Pages: 5219-5225

Published online: 31 Oct 2018

AbstractforypTNM category combined with AJCC tumor regression grade for screening patients with the worst prognosis after neoadjuvant chemoradiation therapy for locally advanced rectal cancer | Full Text | References | PDF (1.4 MB)

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Article

Radiofrequency ablation with systemic chemotherapy in the treatment of colorectal cancer liver metastasis: a 10-year single-center study

Shuangyan Ou, Ruocai Xu, Ke Li, Yong Chen, Yi Kong, Hanchun Liu, Jianliang Li, Yongzhong Ouyang & Xiaoping Yu

Pages: 5227-5237

Published online: 31 Oct 2018

AbstractforRadiofrequency ablation with systemic chemotherapy in the treatment of colorectal cancer liver metastasis: a 10-year single-center study | Full Text | References | PDF (2.6 MB)

67 Views
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Article

Transanal total mesorectal excision for low rectal cancer: a case-matched study comparing TaTME versus standard laparoscopic TME

Mateusz Rubinkiewicz, Michał Nowakowski, Mateusz Wierdak, Magdalena Mizera, Marcin Dembiński, Magdalena Pisarska, Piotr Major, Piotr Małczak, Andrzej Budzyński & Michał Pędziwiatr

Pages: 5239-5245

Published online: 01 Nov 2018

AbstractforTransanal total mesorectal excision for low rectal cancer: a case-matched study comparing TaTME versus standard laparoscopic TME | Full Text | References | PDF (172 KB)

82 Views
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Article

Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review

Hongxing Zhou & Xuming Zhu

Pages: 5247-5259

Published online: 02 Nov 2018

AbstractforAssociation between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review | Full Text | References | PDF (909.1 KB)

72 Views
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Article

Inhibition of long non-coding RNA HOTAIR enhances radiosensitivity via regulating autophagy in pancreatic cancer

Chunli Wu, Liang Yang, Xun Qi, Taifang Wang, Meng Li & Ke Xu

Pages: 5261-5271

Published online: 02 Nov 2018

AbstractforInhibition of long non-coding RNA HOTAIR enhances radiosensitivity via regulating autophagy in pancreatic cancer | Full Text | References | PDF (3.3 MB)

97 Views
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Article

Transcatheter arterial chemoembolization monotherapy vs combined transcatheter arterial chemoembolization–percutaneous microwave coagulation therapy for massive hepatocellular carcinoma (≥10 cm)

Yanyan Wei, Feng Dai, Tianhui Zhao, Chen Tao, Lili Wang, Wei Ye & Wei Zhao

Pages: 5273-5282

Published online: 01 Nov 2018

AbstractforTranscatheter arterial chemoembolization monotherapy vs combined transcatheter arterial chemoembolization–percutaneous microwave coagulation therapy for massive hepatocellular carcinoma (≥10 cm) | Full Text | References | PDF (448.4 KB)

59 Views
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Article

Treatment features of systemic chemotherapy in young adults with unresectable advanced or recurrent gastric cancer

Izuma Nakayama, Keisho Chin, Daisuke Takahari, Mariko Ogura, Takashi Ichimura, Takeru Wakatsuki, Hiroki Osumi, Yumiko Ota, Takeshi Suzuki, Mitsukuni Suenaga, Eiji Shinozaki & Kensei Yamaguchi

Pages: 5283-5290

Published online: 01 Nov 2018

AbstractforTreatment features of systemic chemotherapy in young adults with unresectable advanced or recurrent gastric cancer | Full Text | References | PDF (413.4 KB)

52 Views
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Article

Evaluation and prediction of hepatocellular carcinoma prognosis based on molecular classification

Kun Ke, Geng Chen, Zhixiong Cai, Yanbing Huang, Bixing Zhao, Yingchao Wang, Naishun Liao, Xiaolong Liu, Zhenli Li & Jingfeng Liu

Pages: 5291-5302

Published online: 05 Nov 2018

AbstractforEvaluation and prediction of hepatocellular carcinoma prognosis based on molecular classification | Full Text | References | PDF (2 MB)

114 Views
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Article

A novel 12-marker panel of cancer-associated fibroblasts involved in progression of hepatocellular carcinoma

Baojia Zou, Xialei Liu, Yihang Gong, Chaonong Cai, Peiping Li, Shan Xing, Bibesh Pokhrel, Baimeng Zhang & Jian Li

Pages: 5303-5311

Published online: 05 Nov 2018

AbstractforA novel 12-marker panel of cancer-associated fibroblasts involved in progression of hepatocellular carcinoma | Full Text | References | PDF (3.3 MB)

78 Views
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Article

Diagnostic and prognostic values of the mRNA expression of excision repair cross-complementation enzymes in hepatitis B virus-related hepatocellular carcinoma

Lu Yang, Ming Xu, Chuan-Bao Cui, Peng-Hai Wei, Shu-Zhi Wu, Zuo-Jie Cen, Xing-Xing Meng, Qiong-Guang Huang & Zhi-Chun Xie

Pages: 5313-5328

Published online: 05 Nov 2018

AbstractforDiagnostic and prognostic values of the mRNA expression of excision repair cross-complementation enzymes in hepatitis B virus-related hepatocellular carcinoma | Full Text | References | PDF (2.4 MB)

57 Views
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Article

Breast cancer subtypes and the risk of distant metastasis at initial diagnosis: a population-based study

Weikai Xiao, Shaoquan Zheng, Anli Yang, Xingcai Zhang, Yutian Zou, Hailin Tang & Xiaoming Xie

Pages: 5329-5338

Published online: 05 Nov 2018

AbstractforBreast cancer subtypes and the risk of distant metastasis at initial diagnosis: a population-based study | Full Text | References | PDF (2.3 MB)

303 Views
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Article

Ki-67 index and percentage of sarcomatoid differentiation were two independent prognostic predictors in sarcomatoid renal cell carcinoma

Zhixian Wang, Xiaoyong Zeng, Ruibao Chen & Zhiqiang Chen

Pages: 5339-5347

Published online: 05 Nov 2018

AbstractforKi-67 index and percentage of sarcomatoid differentiation were two independent prognostic predictors in sarcomatoid renal cell carcinoma | Full Text | References | PDF (470.3 KB)

55 Views
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Article

Epigenetic regulation of HOTAIR in advanced chronic myeloid leukemia

Ziye Li & Jianmin Luo

Pages: 5349-5362

Published online: 05 Nov 2018

AbstractforEpigenetic regulation of HOTAIR in advanced chronic myeloid leukemia | Full Text | References | PDF (5.1 MB)

77 Views
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Article

Chemotherapy combined with dendritic cell vaccine and cytokine-induced killer cells in the treatment of colorectal carcinoma: a meta-analysis

Xiuling Zhou, Xiangqiong Mo, Junlan Qiu, Jingjing Zhao, Shuncong Wang, Cuiling Zhou, Yonghui Su, Zhong Lin & Haiqing Ma

Pages: 5363-5372

Published online: 05 Nov 2018

AbstractforChemotherapy combined with dendritic cell vaccine and cytokine-induced killer cells in the treatment of colorectal carcinoma: a meta-analysis | Full Text | References | PDF (483.6 KB)

83 Views
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Article

Urine exosome gene expression of cancer-testis antigens for prediction of bladder carcinoma

Fatemeh Yazarlou, Seyed Javad Mowla, Vahid Kholghi Oskooei, Elahe Motevaseli, Leila Farhady Tooli, Mandana Afsharpad, Leila Nekoohesh, Nafiseh Sadat Sanikhani, Soudeh Ghafouri-Fard & Mohammad Hossein Modarressi

Pages: 5373-5381

Published online: 05 Nov 2018

AbstractforUrine exosome gene expression of cancer-testis antigens for prediction of bladder carcinoma | Full Text | References | PDF (2.5 MB)

102 Views
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Article

Prognostic impact of lactic dehydrogenase to albumin ratio in hepatocellular carcinoma patients with Child–Pugh I who underwent curative resection: a prognostic nomogram study

Wei Gan, Mei-Xia Zhang, Jia-Xing Wang, Yi-Peng Fu, Jin-Long Huang, Yong Yi, Chu-Yu Jing, Jia Fan, Jian Zhou & Shuang-Jian Qiu

Pages: 5383-5394

Published online: 05 Nov 2018

AbstractforPrognostic impact of lactic dehydrogenase to albumin ratio in hepatocellular carcinoma patients with Child–Pugh I who underwent curative resection: a prognostic nomogram study | Full Text | References | PDF (1.4 MB)

64 Views
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Review

Review Article

Dietary vitamin B intake and the risk of esophageal cancer: a meta-analysis

Jun-Li Ma, Yan Zhao, Chen-Yang Guo, Hong-Tao Hu, Lin Zheng, Er-Jiang Zhao & Hai-Liang Li

Pages: 5395-5410

Published online: 05 Nov 2018

AbstractforDietary vitamin B intake and the risk of esophageal cancer: a meta-analysis | Full Text | References | PDF (894.6 KB)

221 Views
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Original Research

Article

Prognostic significance of combined preoperative platelet-to-lymphocyte ratio and lymphocyte-to-monocyte ratio in patients undergoing surgery with stage IB non-small-cell lung cancer

Yongqiang Chen, Weidong Wang, Xuewen Zhang, Xiangyang Yu, Kexing Xi, Yingsheng Wen, Gongming Wang, Xiaoli Feng & Lanjun Zhang

Pages: 5411-5422

Published online: 08 Nov 2018

AbstractforPrognostic significance of combined preoperative platelet-to-lymphocyte ratio and lymphocyte-to-monocyte ratio in patients undergoing surgery with stage IB non-small-cell lung cancer | Full Text | References | PDF (581.6 KB)

64 Views
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Article

Can contemporary trials of chemotherapy for HER2-negative metastatic breast cancer detect overall survival benefit?

Sherko Kümmel, Christian Jackisch, Volkmar Müller, Andreas Schneeweiss, Sandra Klawitter & Michael P Lux

Pages: 5423-5431

Published online: 08 Nov 2018

AbstractforCan contemporary trials of chemotherapy for HER2-negative metastatic breast cancer detect overall survival benefit? | Full Text | References | PDF (226.7 KB)

55 Views
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Article

Feasibility single-arm study of a medical device containing Desmodium adscendens and Lithothamnium calcareum combined with chemotherapy in head and neck cancer patients

Luca Imperatori, Damiano Giardini, Gino Latini, Giuseppe Migliori, Claudio Blasi, Feisal Bunkheila, Cesare Breschi, Rodolfo Mattioli, Silvia Pelliccioni, Carmen Laurino, Maria Vadalà, Beniamino Palmieri & Tommaso Iannitti

Pages: 5433-5438

Published online: 08 Nov 2018

AbstractforFeasibility single-arm study of a medical device containing Desmodium adscendens and Lithothamnium calcareum combined with chemotherapy in head and neck cancer patients | Full Text | References | PDF (389.7 KB)

98 Views
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Article

Nomogram application to predict overall and cancer-specific survival in osteosarcoma

Weipeng Zheng, Yuanping Huang, Haoyi Chen, Ning Wang, Wende Xiao, YingJie Liang, Xin Jiang, Wenzhou Su & Shifeng Wen

Pages: 5439-5450

Published online: 08 Nov 2018

AbstractforNomogram application to predict overall and cancer-specific survival in osteosarcoma | Full Text | References | PDF (2.8 MB)

89 Views
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Article

Histone deacetylase 6 expression in metastatic lymph nodes is a valuable prognostic marker for resected node-positive esophageal squamous cell cancer

Xuan Xie, Kongjia Luo, Yi Li, Yihong Ling, Shuishen Zhang, Xiuying Xie & Jing Wen

Pages: 5451-5460

Published online: 08 Nov 2018

AbstractforHistone deacetylase 6 expression in metastatic lymph nodes is a valuable prognostic marker for resected node-positive esophageal squamous cell cancer | Full Text | References | PDF (2.3 MB)

64 Views
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Article

RETRACTED: Identification of potential key genes associated with ovarian clear cell carcinoma

Youzheng Xu & Keng Shen

Pages: 5461-5470

Published online: 08 Nov 2018

AbstractforRETRACTED: Identification of potential key genes associated with ovarian clear cell carcinoma | PDF (3.9 MB)

27 Views
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Article

RETRACTED ARTICLE: Osthole sensitizes with radiotherapy to suppress tumorigenesis of human nasopharyngeal carcinoma in vitro and in vivo

Lin Peng, Yi-Teng Huang, Jian Chen, Yi-Xuan Zhuang, Fan Zhang, Jiong-Yu Chen, Li Zhou & Dong-Hong Zhang

Pages: 5471-5477

Published online: 08 Nov 2018

AbstractforRETRACTED ARTICLE: Osthole sensitizes with radiotherapy to suppress tumorigenesis of human nasopharyngeal carcinoma in vitro and in vivo | PDF (2.1 MB)

22 Views
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Article

miRNA expression profiles in Smad4-positive and Smad4-negative SW620 human colon cancer cells detected by next-generation small RNA sequencing

Wei Yan, Zhongcai Liu, Wenchao Yang & Guoyang Wu

Pages: 5479-5490

Published online: 08 Nov 2018

AbstractformiRNA expression profiles in Smad4-positive and Smad4-negative SW620 human colon cancer cells detected by next-generation small RNA sequencing | Full Text | References | PDF (3.7 MB)

80 Views
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Article

Upregulation of centromere protein F is linked to aggressive prostate cancers

Cosima Göbel, Cansu Özden, Cornelia Schroeder, Claudia Hube-Magg, Martina Kluth, Christina Möller-Koop, Emily Neubauer, Andrea Hinsch, Frank Jacobsen, Ronald Simon, Guido Sauter, Uwe Michl, Dirk Pehrke, Hartwig Huland, Markus Graefen, Thorsten Schlomm & Andreas M Luebke

Pages: 5491-5504

Published online: 09 Nov 2018

AbstractforUpregulation of centromere protein F is linked to aggressive prostate cancers | Full Text | References | PDF (3.1 MB)

82 Views
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Article

Does the use of targeted agents in advanced gastroesophageal cancer increase complete response? A meta-analysis of 18 randomized controlled trials

Yanyang Pang, Zhen Shen, Jiancheng Sun & Wu Wang

Pages: 5505-5514

Published online: 12 Nov 2018

AbstractforDoes the use of targeted agents in advanced gastroesophageal cancer increase complete response? A meta-analysis of 18 randomized controlled trials | Full Text | References | PDF (1.1 MB)

48 Views
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Article

The role of postoperative radiotherapy in pediatric patients with grade II intracranial ependymomas: a population-based, propensity score-matched study

Xiangyang Deng, Dongdong Lin, Lisheng Yu, Xingxing Xu, Nu Zhang, Hui Zhou, Hansong Sheng, Bo Yin, Fengchun Lin, Shangyu Xu, Dandong Li, Junhao Fang, Xiangqi Lu & Jian Lin

Pages: 5515-5524

Published online: 08 Nov 2018

AbstractforThe role of postoperative radiotherapy in pediatric patients with grade II intracranial ependymomas: a population-based, propensity score-matched study | Full Text | References | PDF (904.8 KB)

68 Views
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Article

Impact of physical activity and sleep quality on quality of life of rural residents with and without a history of cancer: findings of the Day and Night Study

Carlin Rafie, Yi Ning, Aiping Wang, Xiang Gao & Robert Houlihan

Pages: 5525-5535

Published online: 09 Nov 2018

AbstractforImpact of physical activity and sleep quality on quality of life of rural residents with and without a history of cancer: findings of the Day and Night Study | Full Text | References | PDF (192.7 KB)

132 Views
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Article

Risk score for non-small cell lung cancer patients starting checkpoint inhibitor treatment

Stefan Diem, Mirjam Fässler, Omar Hasan Ali, Marco Siano, Rebekka Niederer, Fiamma Berner, Guillaume-Alexandre Roux, Christoph Jakob Ackermann, Sabine Schmid, Sabine Güsewell, Martin Früh & Lukas Flatz

Pages: 5537-5544

Published online: 08 Nov 2018

AbstractforRisk score for non-small cell lung cancer patients starting checkpoint inhibitor treatment | Full Text | References | PDF (825.5 KB)

49 Views
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Article

Transarterial chemoembolization with radiofrequency ablation versus hepatectomy in hepatocellular carcinoma beyond the Milan criteria: a retrospective study

Hang Yuan, Ping Cao, Hai-Liang Li, Hong-Tao Hu, Chen-Yang Guo, Yan Zhao, Quan-Jun Yao & Xiang Geng

Pages: 5545-5552

Published online: 08 Nov 2018

AbstractforTransarterial chemoembolization with radiofrequency ablation versus hepatectomy in hepatocellular carcinoma beyond the Milan criteria: a retrospective study | Full Text | References | PDF (432.3 KB)

45 Views
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Article

Impact of the anterior commissure involvement on the survival of early glottic cancer treated with cricohyoidoepiglottopexy: a retrospective study

Eugenia Allegra, Vincenzo Saita, Alfio Azzolina, Massimo De Natale, Maria Rita Bianco, Domenico Michele Modica & Aldo Garozzo

Pages: 5553-5558

Published online: 08 Nov 2018

AbstractforImpact of the anterior commissure involvement on the survival of early glottic cancer treated with cricohyoidoepiglottopexy: a retrospective study | Full Text | References | PDF (369.9 KB)

66 Views
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Article

Overexpression of RALY promotes migration and predicts poor prognosis in hepatocellular carcinoma

Zebin Zhu, Yixi Zhang, Chensong Huang, Yunhua Tang, Chengjun Sun, Weiqiang Ju & Xiaoshun He

Pages: 5559-5572

Published online: 09 Nov 2018

AbstractforOverexpression of RALY promotes migration and predicts poor prognosis in hepatocellular carcinoma | Full Text | References | PDF (7.6 MB)

55 Views
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Article

Gene expression of hENT1, dCK, CDA, dCMPD and topoisomerase IIα as an indicator of chemotherapy response in AML treated with cytarabine and daunorubicin

Bibi Kulsoom, Tahir Sultan Shamsi & Nasir Ali Afsar

Pages: 5573-5589

Published online: 09 Nov 2018

AbstractforGene expression of hENT1, dCK, CDA, dCMPD and topoisomerase IIα as an indicator of chemotherapy response in AML treated with cytarabine and daunorubicin | Full Text | References | PDF (922.1 KB)

56 Views
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Article

Tumor-suppressive function of SIRT4 in neuroblastoma through mitochondrial damage

Yumei Wang, Yinmou Guo, Jianzhi Gao & Xiangdong Yuan

Pages: 5591-5603

Published online: 09 Nov 2018

AbstractforTumor-suppressive function of SIRT4 in neuroblastoma through mitochondrial damage | Full Text | References | PDF (3.2 MB)

75 Views
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Article

Prognostic value of TIGAR and LC3B protein expression in nasopharyngeal carcinoma

Min Wei, Jinxia Peng, Peng Wu, Ping Chen, Hongru Yang, Yongxia Cui & Linglin Yang

Pages: 5605-5616

Published online: 12 Nov 2018

AbstractforPrognostic value of TIGAR and LC3B protein expression in nasopharyngeal carcinoma | Full Text | References | PDF (2.5 MB)

50 Views
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Review

Review Article

Carotid blowout syndrome: modern trends in management

Carlos Suárez, Verónica Fernández-Alvarez, Marc Hamoir, William M Mendenhall, Primoz Strojan, Miquel Quer, Carl E Silver, Juan P Rodrigo, Alessandra Rinaldo & Alfio Ferlito

Pages: 5617-5628

Published online: 13 Nov 2018

AbstractforCarotid blowout syndrome: modern trends in management | Full Text | References | PDF (813.5 KB)

264 Views
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Original Research

Article

Prognosis of patients with neuroendocrine tumor: a SEER database analysis

Da Man, Jingjing Wu, Zhan Shen & Xiaoyi Zhu

Pages: 5629-5638

Published online: 13 Nov 2018

AbstractforPrognosis of patients with neuroendocrine tumor: a SEER database analysis | Full Text | References | PDF (474.1 KB)

318 Views
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Article

Circulating tumor cells as a potential biomarker for postoperative clinical outcome in HBV-related hepatocellular carcinoma

Xinping Ye, Guanghui Li, Chuangye Han, Quanfa Han, Liming Shang, Hao Su, Bowen Han, Yizhen Gong, Guodong Lu & Tao Peng

Pages: 5639-5647

Published online: 15 Nov 2018

AbstractforCirculating tumor cells as a potential biomarker for postoperative clinical outcome in HBV-related hepatocellular carcinoma | Full Text | References | PDF (1.8 MB)

62 Views
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Article

Brain metastases in newly diagnosed colorectal cancer: a population-based study

Lin Yang, Wenzhuo He, Qiankun Xie, Shousheng Liu, Pengfei Kong, Chang Jiang, Bei Zhang & Liangping Xia

Pages: 5649-5658

Published online: 15 Nov 2018

AbstractforBrain metastases in newly diagnosed colorectal cancer: a population-based study | Full Text | References | PDF (681.5 KB)

63 Views
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Article

IL-8 and thrombospondin-1 as prognostic markers in patients with metastatic colorectal cancer receiving bevacizumab

Giorgia Marisi, Emanuela Scarpi, Alessandro Passardi, Oriana Nanni, Flavia Pagan, Martina Valgiusti, Andrea Casadei Gardini, Luca Maria Neri, Giovanni Luca Frassineti, Dino Amadori & Paola Ulivi

Pages: 5659-5666

Published online: 14 Nov 2018

AbstractforIL-8 and thrombospondin-1 as prognostic markers in patients with metastatic colorectal cancer receiving bevacizumab | Full Text | References | PDF (275 KB)

53 Views
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Article

Influence of marital status on small intestinal adenocarcinoma survival: an analysis of the Surveillance, Epidemiology, and End Results (SEER) database

Zhihui Chen, Ji Cui, Weigang Dai, Hong Yang, Yulong He & Xinming Song

Pages: 5667-5676

Published online: 14 Nov 2018

AbstractforInfluence of marital status on small intestinal adenocarcinoma survival: an analysis of the Surveillance, Epidemiology, and End Results (SEER) database | Full Text | References | PDF (1.1 MB)

51 Views
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Article

The contribution of XRCC3 genotypes to childhood acute lymphoblastic leukemia

Jen-Sheng Pei, Wen-Shin Chang, Pei-Chen Hsu, Chao-Chun Chen, Shun-Ping Cheng, Yun-Chi Wang, Chia-Wen Tsai, Te-Chun Shen & Da-Tian Bau

Pages: 5677-5684

Published online: 15 Nov 2018

AbstractforThe contribution of XRCC3 genotypes to childhood acute lymphoblastic leukemia | Full Text | References | PDF (301.4 KB)

76 Views
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Article

Safety and efficacy of microwave ablation for breast cancer thoracic metastases

Bin Liu, Zhenjie Wu, Hao Mo, Juliang He, Xiang Lin, Jian Guan, Changyuan Wei & Zhenchao Yuan

Pages: 5685-5689

Published online: 14 Nov 2018

AbstractforSafety and efficacy of microwave ablation for breast cancer thoracic metastases | Full Text | References | PDF (916.9 KB)

112 Views
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Article

Comparison of gene expression in liver regeneration and hepatocellular carcinoma formation

Li Yin, Yahao Wang, Xueqiang Guo, Cunshuan Xu & Guoying Yu

Pages: 5691-5708

Published online: 15 Nov 2018

AbstractforComparison of gene expression in liver regeneration and hepatocellular carcinoma formation | Full Text | References | PDF (5.3 MB)

86 Views
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Article

Securidaca–saponins are natural inhibitors of AKT, MCL-1, and BCL2L1 in cervical cancer cells

Titus Chukwuemeka Obasi, Cornelia Braicu, Bogdan Cezar Iacob, Ede Bodoki, Ancuta Jurj, Lajos Raduly, Ilioara Oniga, Ioana Berindan-Neagoe & Radu Oprean

Pages: 5709-5724

Published online: 15 Nov 2018

AbstractforSecuridaca–saponins are natural inhibitors of AKT, MCL-1, and BCL2L1 in cervical cancer cells | Full Text | References | PDF (10.4 MB)

111 Views
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Article

Circ-SFMBT2 promotes the proliferation of gastric cancer cells through sponging miR-182-5p to enhance CREB1 expression

Handong Sun, Pengcheng Xi, Zhiqiang Sun, Qian Wang, Bin Zhu, Jian Zhou, Hui Jin, Wubin Zheng, Weiwei Tang, Hongyong Cao & Xiufeng Cao

Pages: 5725-5734

Published online: 16 Nov 2018

AbstractforCirc-SFMBT2 promotes the proliferation of gastric cancer cells through sponging miR-182-5p to enhance CREB1 expression | Full Text | References | PDF (3.4 MB)

76 Views
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Article

Enolase-1 serves as a biomarker of diagnosis and prognosis in hepatocellular carcinoma patients

Weiwei Zhu, Hongqiang Li, Yan Yu, Jianan Chen, Xiaolong Chen, Fang Ren, Zhigang Ren & Guangying Cui

Pages: 5735-5745

Published online: 15 Nov 2018

AbstractforEnolase-1 serves as a biomarker of diagnosis and prognosis in hepatocellular carcinoma patients | Full Text | References | PDF (3.7 MB)

83 Views
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Article

CDK7 inhibition is a novel therapeutic strategy against GBM both in vitro and in vivo

Wei Meng, Jiajia Wang, Baocheng Wang, Fang Liu, Meng Li, Yang Zhao, Chenran Zhang, Qifeng Li, Juxiang Chen, Liye Zhang, Yujie Tang & Jie Ma

Pages: 5747-5758

Published online: 15 Nov 2018

AbstractforCDK7 inhibition is a novel therapeutic strategy against GBM both in vitro and in vivo | Full Text | References | PDF (4.1 MB)

169 Views
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Article

Identification and validation of a four-miRNA (miRNA-21-5p, miRNA-9-5p, miR-149-5p, and miRNA-30b-5p) prognosis signature in clear cell renal cell carcinoma

Mingzhi Xie, Yufeng Lv, Zhihui Liu, Jingyan Zhang, Chaoyong Liang, Xiaoli Liao, Rong Liang, Yan Lin & Yongqiang Li

Pages: 5759-5766

Published online: 15 Nov 2018

AbstractforIdentification and validation of a four-miRNA (miRNA-21-5p, miRNA-9-5p, miR-149-5p, and miRNA-30b-5p) prognosis signature in clear cell renal cell carcinoma | Full Text | References | PDF (4.1 MB)

105 Views
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Article

CD24 expression and stem-associated features define tumor cell heterogeneity and tumorigenic capacities in a model of carcinogenesis

Paola Ortiz-Montero, Win-Yan Liu-Bordes, Arturo Londoño-Vallejo & Jean-Paul Vernot

Pages: 5767-5784

Published online: 16 Nov 2018

AbstractforCD24 expression and stem-associated features define tumor cell heterogeneity and tumorigenic capacities in a model of carcinogenesis | Full Text | References | PDF (9.6 MB)

83 Views
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Article

Metformin sensitizes hypoxia-induced gefitinib treatment resistance of HNSCC via cell cycle regulation and EMT reversal

Xiteng Yin, Zheng Wei, Chuanhui Song, Chuanchao Tang, Wenguang Xu, Yufeng Wang, Junqi Xie, Zitong Lin & Wei Han

Pages: 5785-5798

Published online: 19 Nov 2018

AbstractforMetformin sensitizes hypoxia-induced gefitinib treatment resistance of HNSCC via cell cycle regulation and EMT reversal | Full Text | References | PDF (7.4 MB)

66 Views
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Article

A 15-lncRNA signature predicts survival and functions as a ceRNA in patients with colorectal cancer

Xuning Wang, Jianguo Zhou, Maolin Xu, Yongfeng Yan, Liang Huang, Yanshen Kuang, Yuansheng Liu, Peng Li, Wei Zheng, Hongyi Liu & Baoqing Jia

Pages: 5799-5806

Published online: 16 Nov 2018

AbstractforA 15-lncRNA signature predicts survival and functions as a ceRNA in patients with colorectal cancer | Full Text | References | PDF (1.6 MB)

87 Views
41 CrossRef citations
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Article

Distinct prognostic value of dynactin subunit 4 (DCTN4) and diagnostic value of DCTN1, DCTN2, and DCTN4 in colon adenocarcinoma

Shijun Wang, Qiaoqi Wang, Xiqian Zhang, Xiwen Liao, Guixian Wang, Long Yu, Wei Zhang, Quanbo Zhou, Shengyun Hu & Weitang Yuan

Pages: 5807-5824

Published online: 16 Nov 2018

AbstractforDistinct prognostic value of dynactin subunit 4 (DCTN4) and diagnostic value of DCTN1, DCTN2, and DCTN4 in colon adenocarcinoma | Full Text | References | PDF (9 MB)

116 Views
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Article

12-HETE facilitates cell survival by activating the integrin-linked kinase/NF-κB pathway in ovarian cancer

Qian Liu, Wenhua Tan, Jianhua Che, Dandan Yuan, Liying Zhang, Yuhong Sun, Xiaolong Yue, Lei Xiao & Yuxia Jin

Pages: 5825-5838

Published online: 16 Nov 2018

Abstractfor12-HETE facilitates cell survival by activating the integrin-linked kinase/NF-κB pathway in ovarian cancer | Full Text | References | PDF (3.1 MB)

60 Views
23 CrossRef citations
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Article

miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA

Xuehua Yang, Jianwei Qiu, Haifeng Kang, Yaming Wang & Junbo Qian

Pages: 5839-5853

Published online: 16 Nov 2018

AbstractformiR-125a-5p suppresses colorectal cancer progression by targeting VEGFA | Full Text | References | PDF (7.5 MB)

93 Views
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Article

FPR1 mediates the tumorigenicity of human cervical cancer cells

Guangming Cao & Zhenyu Zhang

Pages: 5855-5865

Published online: 16 Nov 2018

AbstractforFPR1 mediates the tumorigenicity of human cervical cancer cells | Full Text | References | PDF (4 MB)

84 Views
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Corrigendum

Correction

CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value [Corrigendum]

Page: 5867

Published online: 16 Nov 2018

CitationforCircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value [Corrigendum] | Full Text | PDF (78.1 KB)

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Original Research

Article

Comparative efficacy of different targeted therapies plus fulvestrant for advanced breast cancer following progression on prior endocrine therapy: a network meta-analysis

Tingting Zhang, Fubin Feng, Wenge Zhao, Yan Yao, Jinhui Tian, Chao Zhou, Chuanxin Zang, Cun Liu, Xue Wang & Changgang Sun

Pages: 5869-5880

Published online: 16 Nov 2018

AbstractforComparative efficacy of different targeted therapies plus fulvestrant for advanced breast cancer following progression on prior endocrine therapy: a network meta-analysis | Full Text | References | PDF (777.5 KB)

84 Views
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Article

Development and validation of nomograms for predicting overall and breast cancer-specific survival among patients with triple-negative breast cancer

Lin-Wei Guo, Lin-Miao Jiang, Yue Gong, Hong-Hua Zhang, Xiao-Guang Li, Min He, Wei-Li Sun, Hong Ling & Xin Hu

Pages: 5881-5894

Published online: 19 Nov 2018

AbstractforDevelopment and validation of nomograms for predicting overall and breast cancer-specific survival among patients with triple-negative breast cancer | Full Text | References | PDF (601.9 KB)

81 Views
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Review

Review Article

Molecular characterization and biomarker identification in colorectal cancer: Toward realization of the precision medicine dream

Gaurav Goel

Pages: 5895-5908

Published online: 19 Nov 2018

AbstractforMolecular characterization and biomarker identification in colorectal cancer: Toward realization of the precision medicine dream | Full Text | References | PDF (206.9 KB)

111 Views
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Original Research

Article

Deletion of 3p13 is a late event linked to progression of TMPRSS2:ERG fusion prostate cancer

Martina Kluth, Heinke Volta, Mohammad Hussein, Billurvan Taskin, Sohall Frogh, Christina Möller-Koop, Franziska Büscheck, Frank Jacobsen, Maria Christina Tsourlakis, Andreas M Lübke, Andrea Hinsch, Till Clauditz, Markus Graefen, Hans Heinzer, Hartwig Huland, Sarah Minner, Guido Sauter, Waldemar Wilczak, Thorsten Schlomm & Ronald Simon

Pages: 5909-5917

Published online: 19 Nov 2018

AbstractforDeletion of 3p13 is a late event linked to progression of TMPRSS2:ERG fusion prostate cancer | Full Text | References | PDF (3.2 MB)

56 Views
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Article

Predictors of nodal metastasis and prognostic significance of lymph node ratio and total lymph node count in tracheobronchial adenoid cystic carcinoma

Yang Wo, Shicheng Li, Yuanyong Wang, Tong Lu, Yi Qin, Xiao Sun & Wenjie Jiao

Pages: 5919-5925

Published online: 19 Nov 2018

AbstractforPredictors of nodal metastasis and prognostic significance of lymph node ratio and total lymph node count in tracheobronchial adenoid cystic carcinoma | Full Text | References | PDF (176.9 KB)

47 Views
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Article

Vaginal cuff length during radical hysterectomy is a prognostic factor for stage IB-IIA cervical cancer: a retrospective study

Na Zuo, Hongzhen Hu, Niresh Thapa, Zhen Li, Daqiong Jiang, Xiangyu Meng, Jing Yang, Xiaoxing Chen & Hongbing Cai

Pages: 5927-5935

Published online: 19 Nov 2018

AbstractforVaginal cuff length during radical hysterectomy is a prognostic factor for stage IB-IIA cervical cancer: a retrospective study | Full Text | References | PDF (604.5 KB)

60 Views
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Article

Incidence and prognostic factors of patients with synchronous liver metastases upon initial diagnosis of breast cancer: a population-based study

Hai-yun Zhao, Yue Gong, Fu-gui Ye, Hong Ling & Xin Hu

Pages: 5937-5950

Published online: 20 Nov 2018

AbstractforIncidence and prognostic factors of patients with synchronous liver metastases upon initial diagnosis of breast cancer: a population-based study | Full Text | References | PDF (435.2 KB)

104 Views
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Article

TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival

Wen Xiao, Xuegang Wang, Tao Wang & Jinchun Xing

Pages: 5951-5964

Published online: 20 Nov 2018

AbstractforTRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival | Full Text | References | PDF (7.3 MB)

71 Views
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Article

First-line chemotherapy regimens for locally advanced and metastatic pancreatic adenocarcinoma: a Bayesian analysis

Shuisheng Zhang, Weimin Xie, Yinghua Zou, Shuanghua Xie, Jianwei Zhang, Wei Yuan, Jie Ma, Jiuda Zhao, Cuiling Zheng, Yingtai Chen & Chengfeng Wang

Pages: 5965-5978

Published online: 20 Nov 2018

AbstractforFirst-line chemotherapy regimens for locally advanced and metastatic pancreatic adenocarcinoma: a Bayesian analysis | Full Text | References | PDF (2.4 MB)

50 Views
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Article

High mobility group box 3 as an emerging biomarker in diagnosis and prognosis of hepatocellular carcinoma

Wenjie Zheng, Junling Yang, Zhizhen Dong, Li Wang, Miao Fang, Wei Wu, Dengfu Yao & Min Yao

Pages: 5979-5989

Published online: 20 Nov 2018

AbstractforHigh mobility group box 3 as an emerging biomarker in diagnosis and prognosis of hepatocellular carcinoma | Full Text | References | PDF (2.4 MB)

55 Views
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Article

U94/rep of human herpesvirus 6 inhibits proliferation, invasion, and angiogenesis of glioma

Bin Gu, Lingyun Li, Meng Li, Jinfeng Wang, Guofeng Zhang, Kun Yao & Shizhi Wang

Pages: 5991-6001

Published online: 20 Nov 2018

AbstractforU94/rep of human herpesvirus 6 inhibits proliferation, invasion, and angiogenesis of glioma | Full Text | References | PDF (3.5 MB)

50 Views
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Article

High EIF2B5 mRNA expression and its prognostic significance in liver cancer: a study based on the TCGA and GEO database

Yan Jiao, Zhuo Fu, Yanqing Li, Lingyu Meng & Yahui Liu

Pages: 6003-6014

Published online: 20 Nov 2018

AbstractforHigh EIF2B5 mRNA expression and its prognostic significance in liver cancer: a study based on the TCGA and GEO database | Full Text | References | PDF (9.7 MB)

171 Views
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Erratum

Correction

Prognostic impact of lactic dehydrogenase to albumin ratio in hepatocellular carcinoma patients with Child–Pugh I who underwent curative resection: a prognostic nomogram study [Erratum]

Page: 6015

Published online: 20 Nov 2018

CitationforPrognostic impact of lactic dehydrogenase to albumin ratio in hepatocellular carcinoma patients with Child–Pugh I who underwent curative resection: a prognostic nomogram study [Erratum] | Full Text | PDF (77.8 KB)

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Original Research

Article

Comparative effectiveness of different chemotherapy regimens of advanced-stage Hodgkin lymphoma in adults: a network meta-analysis

Tingting Zhang, Yan Yao, Fubin Feng, Wenge Zhao, Jinhui Tian, Chao Zhou, Xue Wang, Shengjie Dong, Jia Li, Lingyu Qi & Changgang Sun

Pages: 6017-6028

Published online: 22 Nov 2018

AbstractforComparative effectiveness of different chemotherapy regimens of advanced-stage Hodgkin lymphoma in adults: a network meta-analysis | Full Text | References | PDF (969.2 KB)

66 Views
1 CrossRef citations
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Article

Pretreatment neutrophil to lymphocyte and platelet to lymphocyte ratios as predictive factors for the survival of cervical adenocarcinoma patients

Joanna Jonska-Gmyrek, Leszek Gmyrek, Agnieszka Zolciak-Siwinska, Maria Kowalska, Malgorzata Fuksiewicz & Beata Kotowicz

Pages: 6029-6038

Published online: 22 Nov 2018

AbstractforPretreatment neutrophil to lymphocyte and platelet to lymphocyte ratios as predictive factors for the survival of cervical adenocarcinoma patients | Full Text | References | PDF (573.9 KB)

87 Views
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Article

Prognostic significance of the 8th edition of the TNM classification for patients with extensive disease small cell lung cancer

Masayuki Shirasawa, Tomoya Fukui, Seiichiro Kusuhara, Yasuhiro Hiyoshi, Mikiko Ishihara, Masashi Kasajima, Yoshiro Nakahara, Sakiko Otani, Satoshi Igawa, Masanori Yokoba, Hisashi Mitsufuji, Masaru Kubota, Masato Katagiri, Jiichiro Sasaki & Katsuhiko Naoki

Pages: 6039-6047

Published online: 21 Nov 2018

AbstractforPrognostic significance of the 8th edition of the TNM classification for patients with extensive disease small cell lung cancer | Full Text | References | PDF (409.3 KB)

53 Views
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Article

HO-1 is a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy

Chun-Nan Yeh, Ren-Chin Wu, Chi-Tung Cheng, Chun-Yi Tsai, Yau-Ren Chang, Ta-Sen Yeh, Tsung-Han Wu, Wei-Chen Lee & Kun-Chun Chiang

Pages: 6049-6059

Published online: 21 Nov 2018

AbstractforHO-1 is a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy | Full Text | References | PDF (3.5 MB)

59 Views
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Article

A Phase II study of S-1 plus oral leucovorin in heavily treated metastatic colorectal cancer patients

Hung-Chih Hsu, Wen-Chi Chou, Feng-Che Kuan, Kuan-Der Lee, Kun-Ming Rau, Jen-Seng Huang & Tsai-Sheng Yang

Pages: 6061-6070

Published online: 21 Nov 2018

AbstractforA Phase II study of S-1 plus oral leucovorin in heavily treated metastatic colorectal cancer patients | Full Text | References | PDF (1.6 MB)

50 Views
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Article

Radiotherapy as salvage treatment of salivary duct carcinoma in major salivary glands without radical operations

Lu Di, Kai Qian, Chengrun Du, Chunying Shen, Ruiping Zhai, Xiayun He, Xiaoshen Wang, Tingting Xu, Chaosu Hu & Hongmei Ying

Pages: 6071-6078

Published online: 21 Nov 2018

AbstractforRadiotherapy as salvage treatment of salivary duct carcinoma in major salivary glands without radical operations | Full Text | References | PDF (435 KB)

47 Views
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Article

Large-scale analysis reveals a novel risk score to predict overall survival in hepatocellular carcinoma

Yujia Zheng, Yulin Liu, Songfeng Zhao, Zhetian Zheng, Chunyi Shen, Li An & Yongliang Yuan

Pages: 6079-6096

Published online: 21 Nov 2018

AbstractforLarge-scale analysis reveals a novel risk score to predict overall survival in hepatocellular carcinoma | Full Text | References | PDF (14.1 MB)

186 Views
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Article

Integrated analysis reveals key genes with prognostic value in lung adenocarcinoma

Ying-Jian Song, Juan Tan, Xin-Huai Gao & Li-Xin Wang

Pages: 6097-6108

Published online: 21 Nov 2018

AbstractforIntegrated analysis reveals key genes with prognostic value in lung adenocarcinoma | Full Text | References | PDF (3.8 MB)

124 Views
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Article

Recurrence and prognostic model for identifying patients at risk for esophageal cancer after surgery

Dongni Chen, Weidong Wang, Youfang Chen, Jia Hu, Men Yang, Junxian Mo & Zhesheng Wen

Pages: 6109-6120

Published online: 21 Nov 2018

AbstractforRecurrence and prognostic model for identifying patients at risk for esophageal cancer after surgery | Full Text | References | PDF (1.2 MB)

68 Views
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Article

Liver surgery prolongs the survival of patients with gastrointestinal stromal tumor liver metastasis: a retrospective study from a single center

Binyi Xiao, Jianhong Peng, Jinghua Tang, Rongxin Zhang, Cong Li, Junzhong Lin, Peirong Ding, Desen Wan, Zhizhong Pan & Xiaojun Wu

Pages: 6121-6127

Published online: 22 Nov 2018

AbstractforLiver surgery prolongs the survival of patients with gastrointestinal stromal tumor liver metastasis: a retrospective study from a single center | Full Text | References | PDF (298.8 KB)

61 Views
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Article

Notch signaling promotes serrated neoplasia pathway in colorectal cancer through epigenetic modification of EPHB2 and EPHB4

Haifeng Lian, Xingfang Jia, Ning Shi, Shuyang Xie, Jian Wang, Wei Wang, Fengzhen Ma, Haiyan Liu, Aili Wang, Xiankui Cheng & Chengxia Liu

Pages: 6129-6141

Published online: 22 Nov 2018

AbstractforNotch signaling promotes serrated neoplasia pathway in colorectal cancer through epigenetic modification of EPHB2 and EPHB4 | Full Text | References | PDF (4.8 MB)

69 Views
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Article

Construction of a nomogram predicting the overall survival of patients with distantly metastatic non-small-cell lung cancer

Jianqing Deng, Zhipeng Ren, Jiaxin Wen, Bo Wang, Xiaobin Hou, Zhiqiang Xue & Xiangyang Chu

Pages: 6143-6156

Published online: 22 Nov 2018

AbstractforConstruction of a nomogram predicting the overall survival of patients with distantly metastatic non-small-cell lung cancer | Full Text | References | PDF (1.2 MB)

66 Views
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Article

ESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer

Xiong-Bo Guo, Bin Huang, Ying-Hua Pan, Shu-Guang Su & Yan Li

Pages: 6157-6166

Published online: 22 Nov 2018

AbstractforESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer | Full Text | References | PDF (4.4 MB)

108 Views
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Article

The clinical use of pretreatment NLR, PLR, and LMR in patients with esophageal squamous cell carcinoma: evidence from a meta-analysis

Yugui Sun & Lifei Zhang

Pages: 6167-6179

Published online: 22 Nov 2018

AbstractforThe clinical use of pretreatment NLR, PLR, and LMR in patients with esophageal squamous cell carcinoma: evidence from a meta-analysis | Full Text | References | PDF (247.4 KB)

93 Views
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Article

miRNA-299-5p regulates estrogen receptor alpha and inhibits migration and invasion of papillary thyroid cancer cell

Zhihong Wang, Liang He, Wei Sun, Yuan Qin, Wenwu Dong, Ting Zhang, Ping Zhang & Hao Zhang

Pages: 6181-6193

Published online: 22 Nov 2018

AbstractformiRNA-299-5p regulates estrogen receptor alpha and inhibits migration and invasion of papillary thyroid cancer cell | Full Text | References | PDF (3.5 MB)

63 Views
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Article

Glucose deprivation promotes apoptotic response to S1 by enhancing autophagy in human cervical cancer cells

Li Zhou, Qinghuan Kong, Yunhan Zhang, Wei Yang, Shan Yan, Meihui Li, Yidan Wang, Yanjie Zhou, Huimei Yu & Liying Han

Pages: 6195-6204

Published online: 23 Nov 2018

AbstractforGlucose deprivation promotes apoptotic response to S1 by enhancing autophagy in human cervical cancer cells | Full Text | References | PDF (4.5 MB)

70 Views
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Article

Upregulation of KIF20A correlates with poor prognosis in gastric cancer

Yi Sheng, Wei Wang, Bo Hong, Xingwang Jiang, Ruochuan Sun, Qiang Yan, Shangxin Zhang, Mingdian Lu, Shengyi Wang, Zhen Zhang, Wenchu Lin & Yongxiang Li

Pages: 6205-6216

Published online: 23 Nov 2018

AbstractforUpregulation of KIF20A correlates with poor prognosis in gastric cancer | Full Text | References | PDF (3.3 MB)

93 Views
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Article

Value of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28

Chuan Tian, Haifeng Ying, Rongyuan Zhuang, Xiaowei Zhang, Hongmin Lu, Hui Wang, Shuowen Wang, Qi Li, Chungang Wang & Xun Cai

Pages: 6217-6226

Published online: 22 Nov 2018

AbstractforValue of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28 | Full Text | References | PDF (1.4 MB)

59 Views
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Article

Comparison of clinical features and outcomes in patients with extraskeletal vs skeletal Ewing sarcoma: an SEER database analysis of 3,178 cases

Sujing Jiang, Guannan Wang, Jieyu Chen & Ying Dong

Pages: 6227-6236

Published online: 23 Nov 2018

AbstractforComparison of clinical features and outcomes in patients with extraskeletal vs skeletal Ewing sarcoma: an SEER database analysis of 3,178 cases | Full Text | References | PDF (621.7 KB)

86 Views
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Article

A comparison of neoadjuvant chemotherapy with gemcitabine versus docetaxel plus cisplatin in locoregionally advanced nasopharyngeal carcinoma: a propensity score matching analysis

Tongxin Liu, Quanquan Sun, Jing Chen, Fangzheng Wang, Bin Li, Weifeng Qin, Zhimin Ye & Fujun Hu

Pages: 6237-6245

Published online: 23 Nov 2018

AbstractforA comparison of neoadjuvant chemotherapy with gemcitabine versus docetaxel plus cisplatin in locoregionally advanced nasopharyngeal carcinoma: a propensity score matching analysis | Full Text | References | PDF (243.4 KB)

68 Views
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Article

Trends in incidence and mortality of female breast cancer during transition in Central China

Yao Cheng, Yaqiong Yan, Jie Gong, Niannian Yang & Shaofa Nie

Pages: 6247-6255

Published online: 23 Nov 2018

AbstractforTrends in incidence and mortality of female breast cancer during transition in Central China | Full Text | References | PDF (915.4 KB)

87 Views
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Article

Association study of genetic variation of lncRNA MALAT1 with carcinogenesis of colorectal cancer

Kexin Zhao, Si Jin, Bo Wei, Shiqiong Cao & Zhifan Xiong

Pages: 6257-6261

Published online: 23 Nov 2018

AbstractforAssociation study of genetic variation of lncRNA MALAT1 with carcinogenesis of colorectal cancer | Full Text | References | PDF (156 KB)

70 Views
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Article

The association between metabolic syndrome and bladder cancer susceptibility and prognosis: an updated comprehensive evidence synthesis of 95 observational studies involving 97,795,299 subjects

Xiao-Fan Peng, Xiang-Yu Meng, Cheng Wei, Zhen-Hua Xing, Jia-Bin Huang, Zhen-Fei Fang, Xin-Qun Hu, Qi-Ming Liu, Zhao-Wei Zhu & Sheng-Hua Zhou

Pages: 6263-6274

Published online: 26 Nov 2018

AbstractforThe association between metabolic syndrome and bladder cancer susceptibility and prognosis: an updated comprehensive evidence synthesis of 95 observational studies involving 97,795,299 subjects | Full Text | References | PDF (820.5 KB)

91 Views
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Article

Altered epidermal fatty acid-binding protein expression in hepatocellular carcinoma predicts unfavorable outcomes

Jia-bin Lu, Shao-hang Cai, Ying-hua Pan & Jing-ping Yun

Pages: 6275-6284

Published online: 23 Nov 2018

AbstractforAltered epidermal fatty acid-binding protein expression in hepatocellular carcinoma predicts unfavorable outcomes | Full Text | References | PDF (4.5 MB)

54 Views
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Article

Combined fibrinogen and neutrophil–lymphocyte ratio as a predictive factor in resectable colorectal adenocarcinoma

Xiao Li, Bang An, Qi Zhao, Jianni Qi, Wenwen Wang, Di Zhang, Zhen Li & Chengyong Qin

Pages: 6285-6294

Published online: 26 Nov 2018

AbstractforCombined fibrinogen and neutrophil–lymphocyte ratio as a predictive factor in resectable colorectal adenocarcinoma | Full Text | References | PDF (1.8 MB)

55 Views
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Review

Review Article

Anatomy of lymphatic drainage of the esophagus and lymph node metastasis of thoracic esophageal cancer

Yichun Wang, Liyang Zhu, Wanli Xia & Fan Wang

Pages: 6295-6303

Published online: 26 Nov 2018

AbstractforAnatomy of lymphatic drainage of the esophagus and lymph node metastasis of thoracic esophageal cancer | Full Text | References | PDF (3.3 MB)

372 Views
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Original Research

Article

Let-7a inhibits osteosarcoma cell growth and lung metastasis by targeting Aurora-B

Jing-Jing Yu, Wen-Sen Pi, Yuan Cao, Ai-Fen Peng, Zhi-Yuan Cao, Jia-Ming Liu, Shan-Hu Huang, Zhi-Li Liu & Wei Zhang

Pages: 6305-6315

Published online: 26 Nov 2018

AbstractforLet-7a inhibits osteosarcoma cell growth and lung metastasis by targeting Aurora-B | Full Text | References | PDF (6.1 MB)

65 Views
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Article

Development of a prediction model for pancreatic cancer in patients with type 2 diabetes using logistic regression and artificial neural network models

Meng Hsuen Hsieh, Li-Min Sun, Cheng-Li Lin, Meng-Ju Hsieh, Chung-Y Hsu & Chia-Hung Kao

Pages: 6317-6324

Published online: 26 Nov 2018

AbstractforDevelopment of a prediction model for pancreatic cancer in patients with type 2 diabetes using logistic regression and artificial neural network models | Full Text | References | PDF (390.4 KB)

220 Views
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Corrigendum

Correction

Usefulness of plasma D-dimer level for monitoring development of distant organ metastasis in colorectal cancer patients after curative resection [Corrigendum]

Page: 6325

Published online: 26 Nov 2018

CitationforUsefulness of plasma D-dimer level for monitoring development of distant organ metastasis in colorectal cancer patients after curative resection [Corrigendum] | Full Text | PDF (77.4 KB)

41 Views
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Review

Review Article

PRISMA – Practical meta-analysis of applying local triamcinolone acetonide injection for stenosis after esophageal cancer surgery

Wu Wang, Zhen Shen, Baoxin Du & Yanyang Pang

Pages: 6327-6338

Published online: 26 Nov 2018

AbstractforPRISMA – Practical meta-analysis of applying local triamcinolone acetonide injection for stenosis after esophageal cancer surgery | Full Text | References | PDF (1.4 MB)

62 Views
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Original Research

Article

Uridine-cytidine kinase 2 promotes metastasis of hepatocellular carcinoma cells via the Stat3 pathway

Qiming Zhou, Hai Jiang, Jianlong Zhang, Wei Yu, Zhenyu Zhou, Pinbo Huang, Jie Wang & Zhiyu Xiao

Pages: 6339-6355

Published online: 26 Nov 2018

AbstractforUridine-cytidine kinase 2 promotes metastasis of hepatocellular carcinoma cells via the Stat3 pathway | Full Text | References | PDF (7.3 MB)

79 Views
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Article

Urinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer

Fatemeh Yazarlou, Mohammad Hossein Modarressi, Seyed Javad Mowla, Vahid Kholghi Oskooei, Elahe Motevaseli, Leila Farhady Tooli, Leila Nekoohesh, Maryam Eghbali, Soudeh Ghafouri-Fard & Mandana Afsharpad

Pages: 6357-6365

Published online: 26 Nov 2018

AbstractforUrinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer | Full Text | References | PDF (1.8 MB)

143 Views
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Article

Integrated mitochondrial function and cancer-related fatigue in men with prostate cancer undergoing radiation therapy

Chao-Pin Hsiao, Mei-Kuang Chen, Barbara Daly & Charles Hoppel

Pages: 6367-6377

Published online: 26 Nov 2018

AbstractforIntegrated mitochondrial function and cancer-related fatigue in men with prostate cancer undergoing radiation therapy | Full Text | References | PDF (747 KB)

119 Views
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Article

Identification of mTOR inhibitor-resistant genes in cutaneous squamous cell carcinoma

Seong-Lan Yu, Dong Chul Lee, Seung Woo Baek, Do Yeun Cho, Jong Gwon Choi & JaeKu Kang

Pages: 6379-6389

Published online: 27 Nov 2018

AbstractforIdentification of mTOR inhibitor-resistant genes in cutaneous squamous cell carcinoma | Full Text | References | PDF (3.4 MB)

61 Views
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Article

Clinical outcomes of stereotactic body radiotherapy for de novo pulmonary tumors in patients with completely resected early stage non-small cell lung cancer

Qianqian Zhao, Gang Chen, Luxi Ye, Zhaochong Zeng, Shiming Shi & Jian He

Pages: 6391-6398

Published online: 28 Nov 2018

AbstractforClinical outcomes of stereotactic body radiotherapy for de novo pulmonary tumors in patients with completely resected early stage non-small cell lung cancer | Full Text | References | PDF (269 KB)

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Article

Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma

Yingyi Ye, Yingying Wu & Jinyan Wang

Pages: 6399-6407

Published online: 27 Nov 2018

AbstractforPyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma | Full Text | References | PDF (3.1 MB)

79 Views
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Article

Specific clinical and immune features of CD68 in glioma via 1,024 samples

Le Wang, Chaoqi Zhang, Zhen Zhang, Bing Han, Zhibo Shen, Lifeng Li, Shasha Liu, Xuan Zhao, Fanglei Ye & Yi Zhang

Pages: 6409-6419

Published online: 27 Nov 2018

AbstractforSpecific clinical and immune features of CD68 in glioma via 1,024 samples | Full Text | References | PDF (8.9 MB)

81 Views
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Article

Local ablative therapy with or without chemotherapy for non-small-cell lung cancer patients with postoperative oligometastases

Shuheng Shang, Yi Su, Zhaofeng Zhu, Butuo Li, Meiying Guo, Yiyue Xu, Xindong Sun, Linlin Wang & Jinming Yu

Pages: 6421-6429

Published online: 27 Nov 2018

AbstractforLocal ablative therapy with or without chemotherapy for non-small-cell lung cancer patients with postoperative oligometastases | Full Text | References | PDF (424.2 KB)

80 Views
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Article

NLRP6, decreased in gastric cancer, suppresses tumorigenicity of gastric cancer cells

Qingqing Wang, Chunmei Wang & Jinlian Chen

Pages: 6431-6444

Published online: 27 Nov 2018

AbstractforNLRP6, decreased in gastric cancer, suppresses tumorigenicity of gastric cancer cells | Full Text | References | PDF (7.6 MB)

67 Views
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Article

Inhibiting GIT1 reduces the growth, invasion, and angiogenesis of osteosarcoma

Zitao Zhang, Polu Hu, Jin Xiong & Shoufeng Wang

Pages: 6445-6455

Published online: 29 Nov 2018

AbstractforInhibiting GIT1 reduces the growth, invasion, and angiogenesis of osteosarcoma | Full Text | References | PDF (6.6 MB)

58 Views
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Article

Orchestration of immune checkpoints in tumor immune contexture and their prognostic significance in esophageal squamous cell carcinoma

Jing-Jing Zhao, Zi-Qi Zhou, Peng Wang, Chang-Long Chen, Yuan Liu, Qiu-Zhong Pan, Qian Zhu, Yan Tang, De-Sheng Weng & Jian-Chuan Xia

Pages: 6457-6468

Published online: 28 Nov 2018

AbstractforOrchestration of immune checkpoints in tumor immune contexture and their prognostic significance in esophageal squamous cell carcinoma | Full Text | References | PDF (4.4 MB)

84 Views
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Article

A radiomics-based formula for the preoperative prediction of postoperative pancreatic fistula in patients with pancreaticoduodenectomy

Wenyu Zhang, Wei Cai, Baochun He, Nan Xiang, Chihua Fang & Fucang Jia

Pages: 6469-6478

Published online: 28 Nov 2018

AbstractforA radiomics-based formula for the preoperative prediction of postoperative pancreatic fistula in patients with pancreaticoduodenectomy | Full Text | References | PDF (1.2 MB)

76 Views
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Article

Managing the cancer–work interface: the effect of cancer survivorship on unemployment

J Kathleen Tracy, Derek Falk, Rebecca J Thompson, Lily Scheindlin, Fiyinfolu Adetunji & Jennifer E Swanberg

Pages: 6479-6487

Published online: 28 Nov 2018

AbstractforManaging the cancer–work interface: the effect of cancer survivorship on unemployment | Full Text | References | PDF (527.5 KB)

97 Views
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Article

Identification of differentially expressed miRNAs in early-stage cervical cancer with lymph node metastasis across The Cancer Genome Atlas datasets

Qian Chen, Xiaoyun Zeng, Dongping Huang & Xiaoqiang Qiu

Pages: 6489-6504

Published online: 28 Nov 2018

AbstractforIdentification of differentially expressed miRNAs in early-stage cervical cancer with lymph node metastasis across The Cancer Genome Atlas datasets | Full Text | References | PDF (4 MB)

78 Views
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Article

Germline BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance associated with breast/ovarian cancer: a report from North India

Anurag Mehta, Smreti Vasudevan, Sanjeev Kumar Sharma, Dushyant Kumar, Manoj Panigrahi, Moushumi Suryavanshi & Garima Gupta

Pages: 6505-6516

Published online: 30 Nov 2018

AbstractforGermline BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance associated with breast/ovarian cancer: a report from North India | Full Text | References | PDF (734.5 KB)

199 Views
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Article

STAT1 inhibits STAT3 activation in esophageal squamous cell carcinoma

Zhaoyong Liu, Ying Zhang, Yelong Chen, Youbin Lin, Zhen Lin & Hu Wang

Pages: 6517-6523

Published online: 29 Nov 2018

AbstractforSTAT1 inhibits STAT3 activation in esophageal squamous cell carcinoma | Full Text | References | PDF (5 MB)

72 Views
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Article

Radiotherapy improves the survival of patients with extensive-disease small-cell lung cancer: a propensity score matched analysis of Surveillance, Epidemiology, and End Results database

Rui Zhang, Ping Li, Qin Li, Yunfeng Qiao, Tangpeng Xu, Peng Ruan, Qibin Song & Zhenming Fu

Pages: 6525-6535

Published online: 29 Nov 2018

AbstractforRadiotherapy improves the survival of patients with extensive-disease small-cell lung cancer: a propensity score matched analysis of Surveillance, Epidemiology, and End Results database | Full Text | References | PDF (464 KB)

71 Views
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Article

miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer

Yifeng Fang, Xiao Liang, Junfen Xu & Xiujun Cai

Pages: 6537-6547

Published online: 29 Nov 2018

AbstractformiR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer | Full Text | References | PDF (3.5 MB)

96 Views
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Article

Breast cancer laterality and molecular subtype likely share a common risk factor

Shao-Ang Cheng, Li-Zhong Liang, Qi-Lian Liang, Zhen-Yi Huang, Xiao-Xia Peng, Xiao-Cui Hong, Xing-Bo Luo, Gao-Le Yuan, Hui-Jie Zhang & Liang Jiang

Pages: 6549-6554

Published online: 29 Nov 2018

AbstractforBreast cancer laterality and molecular subtype likely share a common risk factor | Full Text | References | PDF (149.4 KB)

86 Views
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Article

Efficacy and safety of crizotinib in patients with anaplastic lymphoma kinase-positive advanced-stage non-small-cell lung cancer

Ahmed Mohieldin, Ayman Rasmy, Mohamed Ashour, Muath Al-Nassar, Rola H Ali & Fahad G El-Enezi

Pages: 6555-6561

Published online: 29 Nov 2018

AbstractforEfficacy and safety of crizotinib in patients with anaplastic lymphoma kinase-positive advanced-stage non-small-cell lung cancer | Full Text | References | PDF (446.7 KB)

77 Views
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Article

Impact of inflammatory markers on survival in patients with limited disease small-cell lung cancer undergoing chemoradiotherapy

Denise Bernhardt, Sophie Aufderstrasse, Laila König, Sebastian Adeberg, Farastuk Bozorgmehr, Petros Christopoulos, Rami A El Shafie, Juliane Hörner-Rieber, Jutta Kappes, Michael Thomas, Felix Herth, Martin Steins, Jürgen Debus & Stefan Rieken

Pages: 6563-6569

Published online: 30 Nov 2018

AbstractforImpact of inflammatory markers on survival in patients with limited disease small-cell lung cancer undergoing chemoradiotherapy | Full Text | References | PDF (368.7 KB)

67 Views
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Article

Human epithelial growth factor receptor 2 in human salivary carcinoma ex pleomorphic adenoma: a potential therapeutic target

Liang Xia, Yang Wang, Yuhua Hu, Chunye Zhang, Ting Gu, Lizhen Wang, Jiang Li, Wenwen Yu & Zhen Tian

Pages: 6571-6579

Published online: 30 Nov 2018

AbstractforHuman epithelial growth factor receptor 2 in human salivary carcinoma ex pleomorphic adenoma: a potential therapeutic target | Full Text | References | PDF (3 MB)

54 Views
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Article

The clinical significance of CCBE1 expression in human colorectal cancer

Yan-Rong Zhao, Hao Liu, Li-Miao Xiao, Can-Guang Jin, Zhi-Peng Zhang & Chun-Guang Yang

Pages: 6581-6590

Published online: 30 Nov 2018

AbstractforThe clinical significance of CCBE1 expression in human colorectal cancer | Full Text | References | PDF (4.5 MB)

55 Views
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Article

Classification of positive surgical margins and tumor recurrence after nephron-sparing surgery for small renal masses

Gang Li, Dong-Sheng Zhu, Zhi-Qiang Lang, Ai-Xiang Wang, Yu-Hong Li, Ren-Ya Zhang & Yuan-Jie Niu

Pages: 6591-6598

Published online: 03 Dec 2018

AbstractforClassification of positive surgical margins and tumor recurrence after nephron-sparing surgery for small renal masses | Full Text | References | PDF (3.7 MB)

60 Views
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Article

Long non-coding RNA 1308 promotes cell invasion by regulating the miR-124/ADAM 15 axis in non-small-cell lung cancer cells

Hongliang Li, Xiaopeng Guo, Qiutian Li, Pengzhan Ran, Xudong Xiang, Yuncang Yuan, Tianqi Dong, Bei Zhu, Lei Wang, Fangfang Li, Chunyan Yang, Dengcai Mu, Dan Wang, Chunjie Xiao & Shangyong Zheng

Pages: 6599-6609

Published online: 03 Dec 2018

AbstractforLong non-coding RNA 1308 promotes cell invasion by regulating the miR-124/ADAM 15 axis in non-small-cell lung cancer cells | Full Text | References | PDF (4 MB)

74 Views
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Article

A nomogram to predict prognosis in patients undergoing sublobar resection for stage IA non-small-cell lung cancer

Heli Yang, Xiangdong Li, Jialun Shi, Hao Fu, Hao Yang, Zhen Liang, Hongchao Xiong & Hui Wang

Pages: 6611-6626

Published online: 04 Dec 2018

AbstractforA nomogram to predict prognosis in patients undergoing sublobar resection for stage IA non-small-cell lung cancer | Full Text | References | PDF (3.5 MB)

62 Views
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Article

Aristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients

Gengyan Xiong, Lin Yao, Peng Hong, Li Yang, Weimin Ci, Libo Liu, Qun He, Kan Gong, Xuesong Li & Liqun Zhou

Pages: 6627-6639

Published online: 04 Dec 2018

AbstractforAristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients | Full Text | References | PDF (959.3 KB)

63 Views
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Article

Fibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells

Jinou Wang, Chang Liu, Xiaoying Chang, Yafei Qi, Zhi Zhu & Xianghong Yang

Pages: 6641-6647

Published online: 04 Dec 2018

AbstractforFibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells | Full Text | References | PDF (3.4 MB)

66 Views
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Article

Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer

Xuan Zhu, Huihui Chen, Yi Yang, Chunjing Xu, Jun Zhou, Jiaojiao Zhou & Yiding Chen

Pages: 6649-6668

Published online: 05 Dec 2018

AbstractforDistinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer | Full Text | References | PDF (4.9 MB)

87 Views
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Article

Low STYK1 expression indicates poor prognosis in gastric cancer

Jian Fang, Hao Wang, Xiao Fang, Na Li, Hailiang Hu, Maohong Bian & Peng Yang

Pages: 6669-6676

Published online: 06 Dec 2018

AbstractforLow STYK1 expression indicates poor prognosis in gastric cancer | Full Text | References | PDF (2.4 MB)

60 Views
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Article

Total lymphocyte count, neutrophil–lymphocyte ratio, and platelet–lymphocyte ratio as prognostic factors in advanced non–small cell lung cancer with chemoradiotherapy

Xinyu Song, Dawei Chen, Ma Yuan, Haiyong Wang & Zhehai Wang

Pages: 6677-6683

Published online: 05 Dec 2018

AbstractforTotal lymphocyte count, neutrophil–lymphocyte ratio, and platelet–lymphocyte ratio as prognostic factors in advanced non–small cell lung cancer with chemoradiotherapy | Full Text | References | PDF (524.1 KB)

90 Views
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Review

Review Article

IL-6 and ovarian cancer: inflammatory cytokines in promotion of metastasis

Landon Browning, Megha R Patel, Eli Bring Horvath, Ken Tawara & Cheryl L Jorcyk

Pages: 6685-6693

Published online: 05 Dec 2018

AbstractforIL-6 and ovarian cancer: inflammatory cytokines in promotion of metastasis | Full Text | References | PDF (1.2 MB)

322 Views
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Original Research

Article

Comparison between NOD/SCID mice and BALB/c mice for patient-derived tumor xenografts model of non-small-cell lung cancer

Jianbin Wu, Juntao Zhang, Mei Jiang, Tianhui Zhang, Yue Wang, Ziyu Wang, Yaodong Miao, Zitong Wang & Weiying Li

Pages: 6695-6703

Published online: 06 Dec 2018

AbstractforComparison between NOD/SCID mice and BALB/c mice for patient-derived tumor xenografts model of non-small-cell lung cancer | Full Text | References | PDF (5.4 MB)

109 Views
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Article

Comparison of totally laparoscopic and open approach in total gastrectomy with D2 lymphadenectomy – systematic review and meta-analysis

Piotr Małczak, Grzegorz Torbicz, Mateusz Rubinkiewicz, Natalia Gajewska, Nadia Sajuk, Kamil Rozmus, Michał Wysocki, Piotr Major, Andrzej Budzyński & Michał Pędziwiatr

Pages: 6705-6714

Published online: 06 Dec 2018

AbstractforComparison of totally laparoscopic and open approach in total gastrectomy with D2 lymphadenectomy – systematic review and meta-analysis | Full Text | References | PDF (1 MB)

54 Views
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Article

Anticancer efficiency of cycloartane triterpenoid derivatives isolated from Cimicifuga yunnanensis Hsiao on triple-negative breast cancer cells

Xiao Li, Wei Wang, Yi Fan, Yue Wei, Li-Qin Yu, Ji-Fu Wei & Yi-Fen Wang

Pages: 6715-6729

Published online: 06 Dec 2018

AbstractforAnticancer efficiency of cycloartane triterpenoid derivatives isolated from Cimicifuga yunnanensis Hsiao on triple-negative breast cancer cells | Full Text | References | PDF (5.7 MB)

93 Views
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Review

Review Article

Hematologic toxicity is rare in relapsed patients treated with belinostat: a systematic review of belinostat toxicity and safety in peripheral T-cell lymphomas

Pamela B Allen & Mary Jo Lechowicz

Pages: 6731-6742

Published online: 06 Dec 2018

AbstractforHematologic toxicity is rare in relapsed patients treated with belinostat: a systematic review of belinostat toxicity and safety in peripheral T-cell lymphomas | Full Text | References | PDF (275 KB)

74 Views
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Review Article

Whole-body magnetic resonance imaging for the assessment of metastatic breast cancer

Marcos Vieira Godinho, Flavia Paiva Proença Lobo Lopes & Flavia Martins Costa

Pages: 6743-6756

Published online: 06 Dec 2018

AbstractforWhole-body magnetic resonance imaging for the assessment of metastatic breast cancer | Full Text | References | PDF (6.4 MB)

109 Views
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Review Article

MALAT1: a potential biomarker in cancer

Zhi-Xing Li, Qiong-Ni Zhu, Hai-Bo Zhang, Yang Hu, Guo Wang & Yuan-Shan Zhu

Pages: 6757-6768

Published online: 06 Dec 2018

AbstractforMALAT1: a potential biomarker in cancer | Full Text | References | PDF (1 MB)

426 Views
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Original Research

Article

Improved virtual surgical planning with 3D- multimodality image for malignant giant pelvic tumors

Xiang Fang, Zeping Yu, Yan Xiong, Fang Yuan, Hongyuan Liu, Fan Wu, Wenli Zhang, Yi Luo, Liuhong Song, Chongqi Tu & Hong Duan

Pages: 6769-6777

Published online: 07 Dec 2018

AbstractforImproved virtual surgical planning with 3D- multimodality image for malignant giant pelvic tumors | Full Text | References | PDF (4.9 MB)

88 Views
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Article

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo

Jie Wang, Huaxin Liang, Meiyan Sun, Lei Zhang, Huijing Xu, Wei Liu, Yan Li, Yue Zhou, Yingya Li & Miao Li

Pages: 6779-6790

Published online: 07 Dec 2018

AbstractforDelta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo | Full Text | References | PDF (6.1 MB)

73 Views
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Article

The positive feedback loop between ILF3 and lncRNA ILF3-AS1 promotes melanoma proliferation, migration, and invasion

Guozhen Gao, Wenjun Li, Sha Liu, Dongmei Han, Xingwei Yao, Juanjuan Jin, Dezhi Han, Weijing Sun & Xiangjun Chen

Pages: 6791-6802

Published online: 11 Dec 2018

AbstractforThe positive feedback loop between ILF3 and lncRNA ILF3-AS1 promotes melanoma proliferation, migration, and invasion | Full Text | References | PDF (2.8 MB)

75 Views
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Review

Review Article

Fertility-preserving treatment in women with early endometrial cancer: the Chinese experience

Yao Wang & Jia-xin Yang

Pages: 6803-6813

Published online: 07 Dec 2018

AbstractforFertility-preserving treatment in women with early endometrial cancer: the Chinese experience | Full Text | References | PDF (236 KB)

105 Views
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Original Research

Article

Prognosis of rare pathological primary urethral carcinoma

Mierxiati Abudurexiti, Jun Wang, Ning Shao, Fang-Ning Wan, Yao Zhu, Bo Dai & Ding-Wei Ye

Pages: 6815-6822

Published online: 07 Dec 2018

AbstractforPrognosis of rare pathological primary urethral carcinoma | Full Text | References | PDF (2 MB)

55 Views
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Review

Review Article

The clinical promise of immunotherapy in triple-negative breast cancer

Praveen Vikas, Nicholas Borcherding & Weizhou Zhang

Pages: 6823-6833

Published online: 10 Dec 2018

AbstractforThe clinical promise of immunotherapy in triple-negative breast cancer | Full Text | References | PDF (2.1 MB)

309 Views
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Original Research

Article

The efficacy and safety of apatinib in Ewing’s sarcoma: a retrospective analysis in one institution

Yitian Wang, Li Min, Yong Zhou, Yi Luo, Hong Duan & Chongqi Tu

Pages: 6835-6842

Published online: 11 Dec 2018

AbstractforThe efficacy and safety of apatinib in Ewing’s sarcoma: a retrospective analysis in one institution | Full Text | References | PDF (1 MB)

52 Views
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Article

Nomograms for predicting survival outcomes in patients with primary tracheal tumors: a large population-based analysis

Junmiao Wen, Di Liu, Xinyan Xu, Donglai Chen, Yongbing Chen, Liang Sun, Jiayan Chen & Min Fan

Pages: 6843-6856

Published online: 11 Dec 2018

AbstractforNomograms for predicting survival outcomes in patients with primary tracheal tumors: a large population-based analysis | Full Text | References | PDF (1,023.5 KB)

68 Views
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Article

HJC0152, a novel STAT3 inhibitor with promising anti-tumor effect in gastric cancer

Xiaoxia Jiang, Mengjie Wu, Zhenzhen Xu, Haohao Wang, Haiyong Wang, Xiongfei Yu, Zhongqi Li & Lisong Teng

Pages: 6857-6867

Published online: 12 Dec 2018

AbstractforHJC0152, a novel STAT3 inhibitor with promising anti-tumor effect in gastric cancer | Full Text | References | PDF (11.8 MB)

81 Views
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Article

The number of resected lymph nodes is associated with the long-term survival outcome in patients with T2 N0 non-small cell lung cancer

Ying-Sheng Wen, Ke-Xing Xi, Ke-Xiang Xi, Ru-Si Zhang, Gong-Ming Wang, Zi-Rui Huang & Lan-Jun Zhang

Pages: 6869-6877

Published online: 12 Dec 2018

AbstractforThe number of resected lymph nodes is associated with the long-term survival outcome in patients with T2 N0 non-small cell lung cancer | Full Text | References | PDF (916.8 KB)

68 Views
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Article

An individual reference limit of the serum CEA–TPA–CA 15-3 tumor marker panel in the surveillance of asymptomatic women following surgery for primary breast cancer

Andrea Nicolini, Angelo Carpi, Paola Ferrari, Riccardo Morganti, Valentina Mazzotti, Vivian Barak & Michael J Duffy

Pages: 6879-6886

Published online: 13 Dec 2018

AbstractforAn individual reference limit of the serum CEA–TPA–CA 15-3 tumor marker panel in the surveillance of asymptomatic women following surgery for primary breast cancer | Full Text | References | PDF (445.8 KB)

102 Views
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Review

Review Article

Key regulator of cellular metabolism, estrogen-related receptor α, a new therapeutic target in endocrine-related gynecological tumor

GuiFen Liu, PengMing Sun, BinHua Dong & Jalid Sehouli

Pages: 6887-6895

Published online: 12 Dec 2018

AbstractforKey regulator of cellular metabolism, estrogen-related receptor α, a new therapeutic target in endocrine-related gynecological tumor | Full Text | References | PDF (3.5 MB)

75 Views
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Original Research

Article

Clinicopathological significance of DAPK promoter methylation in non-small-cell lung cancer: a systematic review and meta-analysis

Yan Zhang, Jiang Wu, Gui Huang & Shouming Xu

Pages: 6897-6904

Published online: 12 Dec 2018

AbstractforClinicopathological significance of DAPK promoter methylation in non-small-cell lung cancer: a systematic review and meta-analysis | Full Text | References | PDF (693 KB)

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Article

MAP2K6 is associated with radiation resistance and adverse prognosis for locally advanced nasopharyngeal carcinoma patients

Zhanzhan Li, Na Li & Liangfang Shen

Pages: 6905-6912

Published online: 12 Dec 2018

AbstractforMAP2K6 is associated with radiation resistance and adverse prognosis for locally advanced nasopharyngeal carcinoma patients | Full Text | References | PDF (1.9 MB)

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Article

Prognostic significance of preoperative serum CEA in primary mucinous ovarian carcinoma: a retrospective cohort study

Wei Lin, Dongyan Cao & Keng Shen

Pages: 6913-6920

Published online: 13 Dec 2018

AbstractforPrognostic significance of preoperative serum CEA in primary mucinous ovarian carcinoma: a retrospective cohort study | Full Text | References | PDF (377.9 KB)

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Article

RETRACTED ARTICLE: Clinical significance and effect of MTDH/AEG-1 in bladder urothelial cancer: a study based on immunohistochemistry, RNA-seq, and in vitro verification

Yu Zhang, Li-jie Zhang, Yi-wu Dang, Sheng-hua Li, Hai-biao Yan & Gang Chen

Pages: 6921-6936

Published online: 14 Dec 2018

AbstractforRETRACTED ARTICLE: Clinical significance and effect of MTDH/AEG-1 in bladder urothelial cancer: a study based on immunohistochemistry, RNA-seq, and in vitro verification | PDF (10.9 MB)

16 Views
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Article

Distinct expression and prognostic value of members of the epidermal growth factor receptor family in ovarian cancer

Quan Zhou, Chao-Nan Hou, Huai-Jie Yang, Ze He & Man-Zhen Zuo

Pages: 6937-6948

Published online: 13 Dec 2018

AbstractforDistinct expression and prognostic value of members of the epidermal growth factor receptor family in ovarian cancer | Full Text | References | PDF (2.3 MB)

66 Views
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Article

Nomograms to predict overall survival and cancer-specific survival in patients with adrenocortical carcinoma

Yan Li, Xiaohui Bian, Junyu Ouyang, Shuyi Wei, Meizhi He & Zelong Luo

Pages: 6949-6959

Published online: 13 Dec 2018

AbstractforNomograms to predict overall survival and cancer-specific survival in patients with adrenocortical carcinoma | Full Text | References | PDF (1.1 MB)

69 Views
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Article

Positive relationship between number of negative lymph nodes and duration of gallbladder cancer cause-specific survival after surgery

Jin-Yong Lin, Dou-Sheng Bai, Bao-Huan Zhou, Ping Chen, Jian-Jun Qian, Sheng-Jie Jin & Guo-Qing Jiang

Pages: 6961-6969

Published online: 13 Dec 2018

AbstractforPositive relationship between number of negative lymph nodes and duration of gallbladder cancer cause-specific survival after surgery | Full Text | References | PDF (602.1 KB)

67 Views
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Article

Centromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survival

Xinxin Wang, Diangang Chen, Jianbao Gao, Haixia Long, Haoran Zha, Anmei Zhang, Chi Shu, Li Zhou, Fei Yang, Bo Zhu & Wei Wu

Pages: 6971-6984

Published online: 14 Dec 2018

AbstractforCentromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survival | Full Text | References | PDF (3 MB)

86 Views
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Article

Efficacy and safety of primary surgery with postoperative radiotherapy in head and neck mucosal melanoma: a single-arm Phase II study

Ji-Jin Yao, Fan Zhang, Guang-Shun Zhang, Xiao-Wu Deng, Wang-Jian Zhang, Wayne R Lawrence, Lu Zou, Xiao-Shi Zhang & Li-Xia Lu

Pages: 6985-6996

Published online: 14 Dec 2018

AbstractforEfficacy and safety of primary surgery with postoperative radiotherapy in head and neck mucosal melanoma: a single-arm Phase II study | Full Text | References | PDF (624.2 KB)

63 Views
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Article

Prognostic value of AIB1 and EIF5A2 in intravesical recurrence after surgery for upper tract urothelial carcinoma

Yong Huang, Jinhuan Wei, Yong Fang, Zhenhua Chen, Junjie Cen, Zihao Feng, Jun Lu, Yanping Liang, Junhang Luo & Wei Chen

Pages: 6997-7011

Published online: 14 Dec 2018

AbstractforPrognostic value of AIB1 and EIF5A2 in intravesical recurrence after surgery for upper tract urothelial carcinoma | Full Text | References | PDF (3 MB)

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Article

Real-world evaluation of carboplatin plus a weekly dose of nab-paclitaxel for patients with advanced non-small-cell lung cancer with interstitial lung disease

Satoshi Igawa, Noriko Nishinarita, Akira Takakura, Takahiro Ozawa, Shinya Harada, Seiichiro Kusuhara, Hideyuki Niwa, Shinji Hosotani, Hideyuki Sone, Yoshiro Nakahara, Tomoya Fukui, Hisashi Mitsufuji, Masanori Yokoba, Masaru Kubota, Masato Katagiri, Jiichiro Sasaki & Katsuhiko Naoki

Pages: 7013-7019

Published online: 14 Dec 2018

AbstractforReal-world evaluation of carboplatin plus a weekly dose of nab-paclitaxel for patients with advanced non-small-cell lung cancer with interstitial lung disease | Full Text | References | PDF (163.7 KB)

56 Views
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Cancer Management and Research, Volume 10, Issue (2018)

Cancer Management and Research, Volume 10, Issue (2018)

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Case Report

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