Cancer Management and Research, Volume 12, Issue (2020)

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Cancer Management and Research, Volume 12, Issue (2020)

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Original Research

Article
Up-Regulation of MicroRNA-21 Indicates Poor Prognosis and Promotes Cell Proliferation in Esophageal Squamous Cell Carcinoma via Upregulation of lncRNA SNHG1
Dongbo Luo, Zhenyi Huang, Hongbo Lv, Yang Wang, Wei Sun & Xiaohong Sun
Pages: 1-14
Published online: 06 Jan 2020
AbstractforUp-Regulation of MicroRNA-21 Indicates Poor Prognosis and Promotes Cell Proliferation in Esophageal Squamous Cell Carcinoma via Upregulation of lncRNA SNHG1 | Full Text | References | PDF (7.8 MB) | EPUB
  • 87 Views
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Open Access
Article
Circular RNA Profiling Reveals That circRNA_104433 Regulates Cell Growth by Targeting miR-497-5p in Gastric Cancer
Weiyuan Wei, Xianwei Mo, Linhai Yan, Mingwei Huang, Yang Yang, Qinwen Jin, Huage Zhong, Wenlong Cao, Kun Wu, Liucheng Wu, Zhao Li, Tingan Wang, Yuzhou Qin & Jiansi Chen
Pages: 15-30
Published online: 06 Jan 2020
AbstractforCircular RNA Profiling Reveals That circRNA_104433 Regulates Cell Growth by Targeting miR-497-5p in Gastric Cancer | Full Text | References | PDF (11.1 MB) | EPUB
  • 102 Views
  • 13 CrossRef citations
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Open Access
Article
Correlation Analysis Between Preoperative Serum Iron Level and Prognosis as Well as Recurrence of HCC After Radical Resection
Yicheng Li, Wentao Xu, Pu Chen, Minjun Liao, Wanying Qin, Weijia Liao & Zhaoquan Huang
Pages: 31-41
Published online: 06 Jan 2020
AbstractforCorrelation Analysis Between Preoperative Serum Iron Level and Prognosis as Well as Recurrence of HCC After Radical Resection | Full Text | References | PDF (2.1 MB) | EPUB
  • 61 Views
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Open Access
Article
Diagnostic Significance of Downregulated circMORC3 as a Molecular Biomarker of Hypopharyngeal Squamous Cell Carcinoma: A Pilot Study
Yang Guo, Qiang Huang, Juan Zheng, Chi-Yao Hsueh, Jiameng Huang, Xiaohui Yuan, Hui Chen & Liang Zhou
Pages: 43-49
Published online: 06 Jan 2020
AbstractforDiagnostic Significance of Downregulated circMORC3 as a Molecular Biomarker of Hypopharyngeal Squamous Cell Carcinoma: A Pilot Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 73 Views
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Open Access

Review

Review Article
The Impact of Ramucirumab Treatment on Survival and Quality of Life in Patients with Gastric Cancer
Rutika Mehta, Anuhya Kommalapati & Richard D Kim
Pages: 51-57
Published online: 07 Jan 2020
AbstractforThe Impact of Ramucirumab Treatment on Survival and Quality of Life in Patients with Gastric Cancer | Full Text | References | PDF (247.7 KB) | EPUB
  • 110 Views
  • 7 CrossRef citations
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Open Access

Original Research

Article
Prognostic Significance of Preoperative Inflammatory Biomarkers and Traditional Clinical Parameters in Patients with Spinal Metastasis from Clear Cell Renal Cell Carcinoma: A Retrospective Study of 95 Patients in a Single Center
Kehan Xu, Jialin Li, Mengzi Hu, Hao Zhang, Jian Yang, Haiyi Gong, Bo Li, Wei Wan & Jianru Xiao
Pages: 59-70
Published online: 07 Jan 2020
AbstractforPrognostic Significance of Preoperative Inflammatory Biomarkers and Traditional Clinical Parameters in Patients with Spinal Metastasis from Clear Cell Renal Cell Carcinoma: A Retrospective Study of 95 Patients in a Single Center | Full Text | References | PDF (5.1 MB) | EPUB
  • 82 Views
  • 8 CrossRef citations
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Open Access
Article
Prevention of Procedural Hypertension in the Irreversible Electroporation Ablation of Liver and Pancreatic Tumors Based on Distance from the Adrenal Gland
Gang Fang, Lizhi Niu & Jibing Chen
Pages: 71-78
Published online: 07 Jan 2020
AbstractforPrevention of Procedural Hypertension in the Irreversible Electroporation Ablation of Liver and Pancreatic Tumors Based on Distance from the Adrenal Gland | Full Text | References | PDF (5.8 MB) | EPUB
  • 78 Views
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Open Access

Review

Review Article
Molecular Mechanisms of Anticancer Activities of Puerarin
Bashir Ahmad, Suliman Khan, Yang Liu, Mengzhou Xue, Ghulam Nabi, Sunjeet Kumar, Mohammed Alshwmi & Abdul Wakeel Qarluq
Pages: 79-90
Published online: 08 Jan 2020
AbstractforMolecular Mechanisms of Anticancer Activities of Puerarin | Full Text | References | PDF (4.5 MB) | EPUB
  • 245 Views
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Open Access

Original Research

Article
Anorexia, Hypertension, Pneumothorax, and Hypothyroidism: Potential Signs of Improved Clinical Outcome Following Apatinib in Advanced Osteosarcoma
Lu Xie, Jie Xu, Xin Sun, Xiaodong Tang, Taiqiang Yan, Rongli Yang & Wei Guo
Pages: 91-102
Published online: 07 Jan 2020
AbstractforAnorexia, Hypertension, Pneumothorax, and Hypothyroidism: Potential Signs of Improved Clinical Outcome Following Apatinib in Advanced Osteosarcoma | Full Text | References | PDF (3.6 MB) | EPUB
  • 104 Views
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Open Access
Article
4E-BP1Thr46 Phosphorylation Association with Poor Prognosis in Quantitative Phosphoproteomics of Portal Vein Tumor Thrombus Revealed that 4E-BP1Thr46 Phosphorylation is Associated with Poor Prognosis in HCC
Xincong Lin, Yao Huang, Ying Sun, Xionghong Tan, Jiahe Ouyang, Bixing Zhao, Yingchao Wang, Xiaohua Xing & Jingfeng Liu
Pages: 103-115
Published online: 07 Jan 2020
Abstractfor4E-BP1Thr46 Phosphorylation Association with Poor Prognosis in Quantitative Phosphoproteomics of Portal Vein Tumor Thrombus Revealed that 4E-BP1Thr46 Phosphorylation is Associated with Poor Prognosis in HCC | Full Text | References | PDF (6.9 MB) | EPUB
  • 83 Views
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Open Access
Article
Validity of serum amyloid A and HMGB1 as biomarkers for early diagnosis of gastric cancer
Ali A Ghweil, Heba A Osman, Mohammed H Hassan, Abeer MM Sabry, Reem E Mahdy, Ahmed RH Ahmed, Ahmed Okasha, Ashraf Khodeary & Hesham H Ameen
Pages: 117-126
Published online: 08 Jan 2020
AbstractforValidity of serum amyloid A and HMGB1 as biomarkers for early diagnosis of gastric cancer | Full Text | References | PDF (2.5 MB) | EPUB
  • 96 Views
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Open Access
Article
Percutaneous Endoscopic Gastrostomy Tube Placement in Patients with Head and Neck Cancer Treated with Radiotherapy
Kristin Lang, Rami A ElShafie, Sati Akbaba, Ronald Koschny, Nina Bougatf, Denise Bernhardt, Stefan E Welte, Sebastian Adeberg, Matthias Häfner, Steffen Kargus, Peter K Plinkert, Jürgen Debus & Stefan Rieken
Pages: 127-136
Published online: 08 Jan 2020
AbstractforPercutaneous Endoscopic Gastrostomy Tube Placement in Patients with Head and Neck Cancer Treated with Radiotherapy | Full Text | References | PDF (1.8 MB) | EPUB
  • 187 Views
  • 9 CrossRef citations
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Open Access
Article
Desmoplastic Reaction and Tumor Budding in Cervical Squamous Cell Carcinoma are Prognostic Factors for Distant Metastasis: A Retrospective Study
Lanqing Cao, Ping-Li Sun, Yangyang He, Min Yao & Hongwen Gao
Pages: 137-144
Published online: 08 Jan 2020
AbstractforDesmoplastic Reaction and Tumor Budding in Cervical Squamous Cell Carcinoma are Prognostic Factors for Distant Metastasis: A Retrospective Study | Full Text | References | PDF (1.7 MB) | EPUB
  • 87 Views
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Open Access
Article
Expression and Prognostic Significance of BANF1 in Triple-Negative Breast Cancer
Genhao Zhang
Pages: 145-150
Published online: 08 Jan 2020
AbstractforExpression and Prognostic Significance of BANF1 in Triple-Negative Breast Cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 92 Views
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Open Access

Review

Review Article
Profile of Quizartinib for the Treatment of Adult Patients with Relapsed/Refractory FLT3-ITD-Positive Acute Myeloid Leukemia: Evidence to Date
Luke Fletcher, Sunil K Joshi & Elie Traer
Pages: 151-163
Published online: 08 Jan 2020
AbstractforProfile of Quizartinib for the Treatment of Adult Patients with Relapsed/Refractory FLT3-ITD-Positive Acute Myeloid Leukemia: Evidence to Date | Full Text | References | PDF (1,000 KB) | EPUB
  • 153 Views
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Open Access

Original Research

Article
The Value of Geriatric Nutritional Risk Index in Evaluating Postoperative Complication Risk and Long-Term Prognosis in Elderly Colorectal Cancer Patients
Shuangyi Tang, Hailun Xie, Jiaan Kuang, Feng Gao, Jialiang Gan & Hesheng Ou
Pages: 165-175
Published online: 09 Jan 2020
AbstractforThe Value of Geriatric Nutritional Risk Index in Evaluating Postoperative Complication Risk and Long-Term Prognosis in Elderly Colorectal Cancer Patients | Full Text | References | PDF (5 MB) | EPUB
  • 194 Views
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Open Access
Article
Circular RNA HIPK3 Promotes EMT of Cervical Cancer Through Sponging miR-338-3p to Up-Regulate HIF-1α
Weiwei Qian, Tingting Huang & Wen Feng
Pages: 177-187
Published online: 09 Jan 2020
AbstractforCircular RNA HIPK3 Promotes EMT of Cervical Cancer Through Sponging miR-338-3p to Up-Regulate HIF-1α | Full Text | References | PDF (1.8 MB) | EPUB
  • 129 Views
  • 47 CrossRef citations
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Open Access
Article
Effectiveness and Feasibility of Complementary Lung-RADS Version 1.1 in Risk Stratification for pGGN in LDCT Lung Cancer Screening in a Chinese Population
Qingcheng Meng, Pengfei Ren, Pengrui Gao, Xinmin Dou, Xuejun Chen, Lanwei Guo & Yongping Song
Pages: 189-198
Published online: 09 Jan 2020
AbstractforEffectiveness and Feasibility of Complementary Lung-RADS Version 1.1 in Risk Stratification for pGGN in LDCT Lung Cancer Screening in a Chinese Population | Full Text | References | PDF (2.8 MB) | EPUB
  • 86 Views
  • 5 CrossRef citations
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Open Access
Article
Long Noncoding RNA LINC00460 Modulates MMP-9 to Promote Cell Proliferation, Invasion and Apoptosis by Targeting miR-539 in Papillary Thyroid Cancer
Xian Zou, Zhi Heng Guo, Qun Li & Pei Song Wang
Pages: 199-207
Published online: 09 Jan 2020
AbstractforLong Noncoding RNA LINC00460 Modulates MMP-9 to Promote Cell Proliferation, Invasion and Apoptosis by Targeting miR-539 in Papillary Thyroid Cancer | Full Text | References | PDF (7.5 MB) | EPUB
  • 71 Views
  • 7 CrossRef citations
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Open Access
Article
Changes and Clinical Significance of Detailed Peripheral Lymphocyte Subsets in Evaluating the Immunity for Cancer Patients
Jinrong Qiu, Fuping Zhou, Xinchun Li, Sufang Zhang, Zhuo Chen, Zenghui Xu, Gaoxiong Lu, Zhi Zhu, Na Ding, Jinxing Lou, Zhenlong Ye & Qijun Qian
Pages: 209-219
Published online: 09 Jan 2020
AbstractforChanges and Clinical Significance of Detailed Peripheral Lymphocyte Subsets in Evaluating the Immunity for Cancer Patients | Full Text | References | PDF (6.2 MB) | EPUB
  • 86 Views
  • 4 CrossRef citations
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Open Access
Article
Prognostic and Clinicopathological Significance of EphB3 and Dysadherin Expression in Extrahepatic Cholangiocarcinoma
Zhengchun Wu, Rushi Liu, Li Xiong, Xiongying Miao, Daiqiang Li, Qiong Zou, Yuan Yuan & Zhulin Yang
Pages: 221-232
Published online: 10 Jan 2020
AbstractforPrognostic and Clinicopathological Significance of EphB3 and Dysadherin Expression in Extrahepatic Cholangiocarcinoma | Full Text | References | PDF (8.2 MB) | EPUB
  • 65 Views
  • 5 CrossRef citations
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Open Access
Article
miR106a Promotes the Growth of Transplanted Breast Cancer and Decreases the Sensitivity of Transplanted Tumors to Cisplatin
Faping You, Junhui Li, Peijin Zhang, Hui Zhang & Xuchen Cao
Pages: 233-246
Published online: 13 Jan 2020
AbstractformiR106a Promotes the Growth of Transplanted Breast Cancer and Decreases the Sensitivity of Transplanted Tumors to Cisplatin | Full Text | References | PDF (14.1 MB) | EPUB
  • 71 Views
  • 11 CrossRef citations
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Open Access
Article
Allylated Curcumin Analog CA6 Inhibits TrxR1 and Leads to ROS-Dependent Apoptotic Cell Death in Gastric Cancer Through Akt-FoxO3a
Vinothkumar Rajamanickam, Tao Yan, Liangrong Wu, Yanni Zhao, Xiaohong Xu, Heping Zhu, Xi Chen, Meihong Wang, Zhoudi Liu, Zhiguo Liu, Guang Liang & Yi Wang
Pages: 247-263
Published online: 13 Jan 2020
AbstractforAllylated Curcumin Analog CA6 Inhibits TrxR1 and Leads to ROS-Dependent Apoptotic Cell Death in Gastric Cancer Through Akt-FoxO3a | Full Text | References | PDF (13.3 MB) | EPUB
  • 100 Views
  • 16 CrossRef citations
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Open Access
Article
ERα36 as a Potential Therapeutic Target for Tamoxifen-Resistant Breast Cancer Cell Line Through EGFR/ERK Signaling Pathway
Guangliang Li, Jing Zhang, Zhenzhen Xu & Zhongqi Li
Pages: 265-275
Published online: 14 Jan 2020
AbstractforERα36 as a Potential Therapeutic Target for Tamoxifen-Resistant Breast Cancer Cell Line Through EGFR/ERK Signaling Pathway | Full Text | References | PDF (4.1 MB) | EPUB
  • 121 Views
  • 14 CrossRef citations
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Open Access
Article
LncRNA CASC9 Affects Cell Proliferation, Migration, and Invasion of Tongue Squamous cell Carcinoma via Regulating miR-423-5p/SOX12 Axes
Xin Chen, Hanfeng Xu, Guowen Sun & Ying Zhang
Pages: 277-287
Published online: 14 Jan 2020
AbstractforLncRNA CASC9 Affects Cell Proliferation, Migration, and Invasion of Tongue Squamous cell Carcinoma via Regulating miR-423-5p/SOX12 Axes | Full Text | References | PDF (6.5 MB) | EPUB
  • 65 Views
  • 12 CrossRef citations
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Open Access
Article
Long Noncoding MAGI2-AS3 Suppresses Several Cellular Processes of Lung Squamous Cell Carcinoma Cells by Regulating miR-374a/b-5p/CADM2 Axis
Jia He, Xiaoyun Zhou, Li Li & Zhijun Han
Pages: 289-302
Published online: 15 Jan 2020
AbstractforLong Noncoding MAGI2-AS3 Suppresses Several Cellular Processes of Lung Squamous Cell Carcinoma Cells by Regulating miR-374a/b-5p/CADM2 Axis | Full Text | References | PDF (10.7 MB) | EPUB
  • 73 Views
  • 16 CrossRef citations
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Open Access
Article
Siva 1 Inhibits Cervical Cancer Progression and Its Clinical Prognosis Significance
Ting Liu, Yifei Ma, Zhiling Wang, Wenjing Zhang & Xingsheng Yang
Pages: 303-311
Published online: 15 Jan 2020
AbstractforSiva 1 Inhibits Cervical Cancer Progression and Its Clinical Prognosis Significance | Full Text | References | PDF (5.5 MB) | EPUB
  • 90 Views
  • 3 CrossRef citations
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Open Access
Article
Self-reported sleep quality as prognostic for survival in lung cancer patients
Teodor Gottfried, Iris Kamer, Iris Salant, Damien Urban, Yaacov R Lawrence, Amir Onn & Jair Bar
Pages: 313-321
Published online: 15 Jan 2020
AbstractforSelf-reported sleep quality as prognostic for survival in lung cancer patients | Full Text | References | PDF (1.8 MB) | EPUB
  • 156 Views
  • 15 CrossRef citations
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Open Access
Article
High Preoperative Controlling Nutritional Status Score Predicts a Poor Prognosis in Patients with Localized Upper Tract Urothelial Cancer: A Propensity Score Matching Study in a Large Chinese Center
Zhengqing Bao, Yifan Li, Bao Guan, Gengyan Xiong, Lei Zhang, Qi Tang, Tianyu Wang, Xuesong Li, Dong Fang & Liqun Zhou
Pages: 323-335
Published online: 15 Jan 2020
AbstractforHigh Preoperative Controlling Nutritional Status Score Predicts a Poor Prognosis in Patients with Localized Upper Tract Urothelial Cancer: A Propensity Score Matching Study in a Large Chinese Center | Full Text | References | PDF (3.2 MB) | EPUB
  • 68 Views
  • 11 CrossRef citations
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Open Access
Article
Knockdown of ATAD2 Inhibits Proliferation and Tumorigenicity Through the Rb-E2F1 Pathway and Serves as a Novel Prognostic Indicator in Gastric Cancer
Xuan Zhou, Huihui Ji, Dongxue Ye, Hong Li, Fen Liu, Haiyan Li, Jin Xu, Yujun Li & Fenggang Xiang
Pages: 337-351
Published online: 15 Jan 2020
AbstractforKnockdown of ATAD2 Inhibits Proliferation and Tumorigenicity Through the Rb-E2F1 Pathway and Serves as a Novel Prognostic Indicator in Gastric Cancer | Full Text | References | PDF (12.7 MB) | EPUB
  • 81 Views
  • 8 CrossRef citations
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Open Access

Review

Review Article
Characterization of the Golgi scaffold protein PAQR3, and its role in tumor suppression and metabolic pathway compartmentalization
Lan Lei, Zhe-Nan Ling, Xiang-Liu Chen, Lian-Lian Hong & Zhi-Qiang Ling
Pages: 353-362
Published online: 16 Jan 2020
AbstractforCharacterization of the Golgi scaffold protein PAQR3, and its role in tumor suppression and metabolic pathway compartmentalization | Full Text | References | PDF (1.8 MB) | EPUB
  • 93 Views
  • 10 CrossRef citations
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Open Access

Original Research

Article
RETRACTED ARTICLE: Long Non-Coding RNA LINC01783 Promotes the Progression of Cervical Cancer by Sponging miR-199b-5p to Mediate GBP1 Expression
Wei-jun Chen, Liang Xiong, Lin Yang, Li-juan Yang, Lin Li, Li Huang, Xiao-qing Liang, Jie Xue & Bu-zhen Tan
Pages: 363-373
Published online: 16 Jan 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA LINC01783 Promotes the Progression of Cervical Cancer by Sponging miR-199b-5p to Mediate GBP1 Expression | PDF (10.9 MB)
  • 18 Views
  • 10 CrossRef citations
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Open Access
Article
NSD2 Promotes Renal Cancer Progression Through Stimulating Akt/Erk Signaling
Xu Han, Lianhua Piao, Xiaoshuang Xu, Fengbao Luo, Zhiwei Liu & Xiaozhou He
Pages: 375-383
Published online: 16 Jan 2020
AbstractforNSD2 Promotes Renal Cancer Progression Through Stimulating Akt/Erk Signaling | Full Text | References | PDF (6.9 MB) | EPUB
  • 93 Views
  • 10 CrossRef citations
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Open Access
Article
The Prognostic Value of Preoperative Geriatric Nutritional Risk Index in Patients with Pancreatic Ductal Adenocarcinoma
Si-Pin Hu, Lei Chen, Chen-Yi Lin, Wei-Hang Lin, Fu-Quan Fang & Meng-Yun Tu
Pages: 385-395
Published online: 16 Jan 2020
AbstractforThe Prognostic Value of Preoperative Geriatric Nutritional Risk Index in Patients with Pancreatic Ductal Adenocarcinoma | Full Text | References | PDF (5 MB) | EPUB
  • 75 Views
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Open Access

Review

Review Article
Research Progress Evaluating the Function and Mechanism of Anti-Tumor Peptides
Xinxing Pan, Juan Xu & Xuemei Jia
Pages: 397-409
Published online: 16 Jan 2020
AbstractforResearch Progress Evaluating the Function and Mechanism of Anti-Tumor Peptides | Full Text | References | PDF (1.2 MB) | EPUB
  • 275 Views
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Open Access

Original Research

Article
Preoperative Bilirubin-Adjusted Carbohydrate Antigen 19-9 as a Prognostic Factor for Extrahepatic Cholangiocarcinoma Patients at a Single Center
Jiayi Li, Qiao Chen, Bao Jin, Yue Shi, Xiangan Wu, Haifeng Xu, Yongchang Zheng, Yingyi Wang, Shunda Du, Xin Lu, Yilei Mao & Xinting Sang
Pages: 411-417
Published online: 20 Jan 2020
AbstractforPreoperative Bilirubin-Adjusted Carbohydrate Antigen 19-9 as a Prognostic Factor for Extrahepatic Cholangiocarcinoma Patients at a Single Center | Full Text | References | PDF (652.1 KB) | EPUB
  • 76 Views
  • 1 CrossRef citations
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Open Access
Article
RETRACTED ARTICLE: MicroRNA-802 Inhibits Cell Proliferation and Induces Apoptosis in Human Laryngeal Cancer by Targeting cAMP-Regulated Phosphoprotein 19
Huafu Ye, Qiaozhi Jin, Xiaoqiong Wang & Yong Li
Pages: 419-430
Published online: 20 Jan 2020
AbstractforRETRACTED ARTICLE: MicroRNA-802 Inhibits Cell Proliferation and Induces Apoptosis in Human Laryngeal Cancer by Targeting cAMP-Regulated Phosphoprotein 19 | PDF (8.2 MB)
  • 21 Views
  • 6 CrossRef citations
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Open Access
Article
Efficiency and Tolerability of Induction and Consolidation Therapy with Arsenic Trioxide/Bortezomib/Ascorbic Acid/Dexamethasone (ABCD) Regimen Compared to Bortezomib/Dexamethasone (BD) Regimen in Newly Diagnosed Myeloma Patients
Wensi Qian, Li Wang, Pei Li, Yingwei Hu, Qian Wang, Ke Yi, Min Wu, Yu Xu, Jin Song, Pingping Chen, Hongdi Zhang, Jiexian Ma & Yanhui Xie
Pages: 431-441
Published online: 20 Jan 2020
AbstractforEfficiency and Tolerability of Induction and Consolidation Therapy with Arsenic Trioxide/Bortezomib/Ascorbic Acid/Dexamethasone (ABCD) Regimen Compared to Bortezomib/Dexamethasone (BD) Regimen in Newly Diagnosed Myeloma Patients | Full Text | References | PDF (1.7 MB) | EPUB
  • 81 Views
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Open Access
Article
LncRNA WT1-AS Downregulates Survivin by Upregulating miR-203 in Papillary Thyroid Carcinoma
Fei Le, Ping Luo, Qian Ouyang & Xiaoming Zhong
Pages: 443-449
Published online: 20 Jan 2020
AbstractforLncRNA WT1-AS Downregulates Survivin by Upregulating miR-203 in Papillary Thyroid Carcinoma | Full Text | References | PDF (504.3 KB) | EPUB
  • 72 Views
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Open Access
Article
Predictors of Survival Among Colorectal Cancer Patients in a Low Incidence Area
Nahla Azzam, Yazed AlRuthia, Othman Alharbi, Abdulrahman Aljebreen, Majid Almadi, Maryam Alarfaj, Khalid Alsaleh, Abdulaziz Almasoud, Muhannad Alsharidah, Sarah Alseneidi, Fatimah Alali & Malak Alalwan
Pages: 451-459
Published online: 21 Jan 2020
AbstractforPredictors of Survival Among Colorectal Cancer Patients in a Low Incidence Area | Full Text | References | PDF (1.4 MB) | EPUB
  • 86 Views
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Open Access

Retraction

Retraction
Clinical Significance and Effect of MTDH/AEG-I in Bladder Urothelial Cancer: A Study Based on Immunohistochemistry, RNA-Seq, and in vitro Verification [Retraction]
Page: 461
Published online: 21 Jan 2020
CitationforClinical Significance and Effect of MTDH/AEG-I in Bladder Urothelial Cancer: A Study Based on Immunohistochemistry, RNA-Seq, and in vitro Verification [Retraction] | Full Text | PDF (151.3 KB) | EPUB
  • 61 Views
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Open Access

Original Research

Article
RETRACTED ARTICLE: LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis
Wei Liu, Yu-Jia Yang & Qiang An
Pages: 463-473
Published online: 21 Jan 2020
AbstractforRETRACTED ARTICLE: LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis | PDF (9.3 MB)
  • 78 Views
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Open Access
Article
High Systemic Immune-Inflammation Index Predicts Poor Survival in Patients with Human Epidermal Growth Factor Receptor-2 Positive Breast Cancer Receiving Adjuvant Trastuzumab
Li Jiang, Jianjiang Fang & Jinhua Ding
Pages: 475-484
Published online: 21 Jan 2020
AbstractforHigh Systemic Immune-Inflammation Index Predicts Poor Survival in Patients with Human Epidermal Growth Factor Receptor-2 Positive Breast Cancer Receiving Adjuvant Trastuzumab | Full Text | References | PDF (1.7 MB) | EPUB
  • 98 Views
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Open Access
Article
Combination of Serum miRNAs with Serum Exosomal miRNAs in Early Diagnosis for Non-Small-Cell Lung Cancer
Qingwei Wu, Lili Yu, Xiaoqing Lin, Qingzhu Zheng, Songgao Zhang, Dunyan Chen, Xiaojie Pan & Yi Huang
Pages: 485-495
Published online: 21 Jan 2020
AbstractforCombination of Serum miRNAs with Serum Exosomal miRNAs in Early Diagnosis for Non-Small-Cell Lung Cancer | Full Text | References | PDF (9 MB) | EPUB
  • 173 Views
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Open Access
Article
RETRACTED ARTICLE: Procyanidin Compound (PC) Suppresses Lipopolysaccharide-Induced Cervical Cancer Cell Proliferation Through Blocking the TLR4/NF-κB Pathway
Haiyan Yang, Ziyu Fang, Xiaoli Qu, Xiaoli Zhang & Yifeng Wang
Pages: 497-509
Published online: 22 Jan 2020
AbstractforRETRACTED ARTICLE: Procyanidin Compound (PC) Suppresses Lipopolysaccharide-Induced Cervical Cancer Cell Proliferation Through Blocking the TLR4/NF-κB Pathway | PDF (11 MB)
  • 16 Views
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Open Access
Article
Cosmc Disruption-Mediated Aberrant O-glycosylation Suppresses Breast Cancer Cell Growth via Impairment of CD44
Tan Du, Xingyuan Jia, Xichen Dong, Xiaoli Ru, Lina Li, Yakun Wang, Jian Liu, Guosheng Feng & Tao Wen
Pages: 511-522
Published online: 22 Jan 2020
AbstractforCosmc Disruption-Mediated Aberrant O-glycosylation Suppresses Breast Cancer Cell Growth via Impairment of CD44 | Full Text | References | PDF (7.6 MB) | EPUB
  • 111 Views
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Open Access
Article
CASC11 Overexpression Predicts Poor Prognosis and Regulates Cell Proliferation and Apoptosis in Ovarian Carcinoma
Ying Cui, Guihua Shen, Dan Zhou & Fengli Wu
Pages: 523-529
Published online: 22 Jan 2020
AbstractforCASC11 Overexpression Predicts Poor Prognosis and Regulates Cell Proliferation and Apoptosis in Ovarian Carcinoma | Full Text | References | PDF (842.6 KB) | EPUB
  • 80 Views
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Open Access
Article
Identification of BRMS1L as Metastasis Suppressing Gene in Esophageal Squamous Cell Carcinoma
Ruihao Zhou, Xiaofeng Tang, Liping Li, Feifei Zhang, Jun Sun, Cheng Ju, Yan Zhou, Renfeng Liu, Yiping Liang, Bin Lv, Zhiping Zhang, Haiyan Hu & Xiao-Bin Lv
Pages: 531-539
Published online: 23 Jan 2020
AbstractforIdentification of BRMS1L as Metastasis Suppressing Gene in Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (6.1 MB) | EPUB
  • 74 Views
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Open Access

Corrigendum

Correction
Prognostic Role of a New Inflammatory Index with Neutrophil-to-Lymphocyte Ratio and Lactate Dehydrogenase (CII: Colon Inflammatory Index) in Patients with Metastatic Colorectal Cancer: Results from the Randomized Italian Trial in Advanced Colorectal Cancer (ITACa) Study [Corrigendum]
Page: 541
Published online: 23 Jan 2020
CitationforPrognostic Role of a New Inflammatory Index with Neutrophil-to-Lymphocyte Ratio and Lactate Dehydrogenase (CII: Colon Inflammatory Index) in Patients with Metastatic Colorectal Cancer: Results from the Randomized Italian Trial in Advanced Colorectal Cancer (ITACa) Study [Corrigendum] | Full Text | PDF (150.3 KB) | EPUB
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Article
Expression Profiles of DNA Methylation and Demethylation Machinery Components in Pediatric Myelodysplastic Syndrome: Clinical Implications
Viviane Lamim Lovatel, Cecilia de Souza Fernandez, Eliane Ferreira Rodrigues, Rita de Cassia Tavares, Elaine Sobral da Costa, Eliana Abdelhay, Sheila Coelho Soares Lima & Teresa de Souza Fernandez
Pages: 543-556
Published online: 23 Jan 2020
AbstractforExpression Profiles of DNA Methylation and Demethylation Machinery Components in Pediatric Myelodysplastic Syndrome: Clinical Implications | Full Text | References | PDF (974.2 KB) | EPUB
  • 86 Views
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Article
Impact of the Body Mass Index on Hemorrhage After Surgery for Thyroid Cancer
Peng Li, Ruihua Luo, Lanwei Guo, Wenlu Li & Jinxing Qi
Pages: 557-565
Published online: 23 Jan 2020
AbstractforImpact of the Body Mass Index on Hemorrhage After Surgery for Thyroid Cancer | Full Text | References | PDF (299.6 KB) | EPUB
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Article
RETRACTED ARTICLE: Long Noncoding RNA ZFPM2-AS1 Enhances the Malignancy of Cervical Cancer by Functioning as a Molecular Sponge of microRNA-511-3p and Consequently Increasing FGFR2 Expression
Jun Dai, Rujia Wei, Peihai Zhang & Peishu Liu
Pages: 567-580
Published online: 23 Jan 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA ZFPM2-AS1 Enhances the Malignancy of Cervical Cancer by Functioning as a Molecular Sponge of microRNA-511-3p and Consequently Increasing FGFR2 Expression | PDF (7.4 MB)
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Article
Diagnosis and Surgical Treatment and Pathological Findings of Solid Pseudopapillary Tumor of the Pancreas: A Single-Institution Experience
Tong Guo, Lu Wang, Peng Xie, Zhiwei Zhang & Yahong Yu
Pages: 581-588
Published online: 23 Jan 2020
AbstractforDiagnosis and Surgical Treatment and Pathological Findings of Solid Pseudopapillary Tumor of the Pancreas: A Single-Institution Experience | Full Text | References | PDF (1.9 MB) | EPUB
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Article
Clinicopathological and Prognostic Significance of EML4-ALK Rearrangement in Patients with Surgically Resected Lung Adenocarcinoma: A Propensity Score Matching Study
Jinghan Shi, Weiqing Gu, Yanfeng Zhao, Junjie Zhu, Gening Jiang, Minwei Bao & Jingyun Shi
Pages: 589-598
Published online: 24 Jan 2020
AbstractforClinicopathological and Prognostic Significance of EML4-ALK Rearrangement in Patients with Surgically Resected Lung Adenocarcinoma: A Propensity Score Matching Study | Full Text | References | PDF (348.1 KB) | EPUB
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Article
ZNF671 Inhibits the Proliferation and Metastasis of NSCLC via the Wnt/β-Catenin Pathway
Wei Zhan, Yuzhe Li, Xuhui Liu, Changlong Zheng & Yongmei Fu
Pages: 599-610
Published online: 24 Jan 2020
AbstractforZNF671 Inhibits the Proliferation and Metastasis of NSCLC via the Wnt/β-Catenin Pathway | Full Text | References | PDF (9.5 MB) | EPUB
  • 70 Views
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Article
Effect of RSK4 on Biological Characteristics of Gastric Cancer
Cong Hu, Jun Dai, Xu Lin, Ya Meng & Hui Liang
Pages: 611-619
Published online: 28 Jan 2020
AbstractforEffect of RSK4 on Biological Characteristics of Gastric Cancer | Full Text | References | PDF (7.7 MB) | EPUB
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Article
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer
Xiao-Yu Yan, Juan-Juan Zhang, Xin-Ru Zhong, Si-Hang Yu, Long Xu, Rui Tian, Lian-Kun Sun & Jing Su
Pages: 621-631
Published online: 28 Jan 2020
AbstractforThe LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer | Full Text | References | PDF (7.7 MB) | EPUB
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Article
Carbon Ion Beam Reirradiation in Recurrent High-Grade Glioma
Fabian Eberle, Stefan Lautenschläger, Rita Engenhart-Cabillic, Alexandra D Jensen, Barbara Carl, Marco Stein, Jürgen Debus & Henrik Hauswald
Pages: 633-639
Published online: 28 Jan 2020
AbstractforCarbon Ion Beam Reirradiation in Recurrent High-Grade Glioma | Full Text | References | PDF (613.8 KB) | EPUB
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Article
Paeonol Inhibits Pancreatic Cancer Cell Migration and Invasion Through the Inhibition of TGF-β1/Smad Signaling and Epithelial-Mesenchymal-Transition
Chien-Shan Cheng, Jing-Xian Chen, Jian Tang, Ya-Wen Geng, Lan Zheng, Ling-Ling Lv, Lian-Yu Chen & Zhen Chen
Pages: 641-651
Published online: 29 Jan 2020
AbstractforPaeonol Inhibits Pancreatic Cancer Cell Migration and Invasion Through the Inhibition of TGF-β1/Smad Signaling and Epithelial-Mesenchymal-Transition | Full Text | References | PDF (8.4 MB) | EPUB
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Article
Fourier Transform Infrared Spectroscopy Monitoring of Dihydroartemisinin-Induced Growth Inhibition in Ovarian Cancer Cells and Normal Ovarian Surface Epithelial Cells
Lei Li, Jinguang Wu, Shifu Weng, Limin Yang, Huizi Wang, Yizhuang Xu & Keng Shen
Pages: 653-661
Published online: 29 Jan 2020
AbstractforFourier Transform Infrared Spectroscopy Monitoring of Dihydroartemisinin-Induced Growth Inhibition in Ovarian Cancer Cells and Normal Ovarian Surface Epithelial Cells | Full Text | References | PDF (5.4 MB) | EPUB
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Article
Decreasing Microtubule Actin Cross-Linking Factor 1 Inhibits Melanoma Metastasis by Decreasing Epithelial to Mesenchymal Transition
Xiaoying Wang, Xiao Jian, Jun Dou, Zicheng Wei & Fengshu Zhao
Pages: 663-673
Published online: 29 Jan 2020
AbstractforDecreasing Microtubule Actin Cross-Linking Factor 1 Inhibits Melanoma Metastasis by Decreasing Epithelial to Mesenchymal Transition | Full Text | References | PDF (5.8 MB) | EPUB
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Review

Review Article
Strategies for Increasing the Effectiveness of Aromatase Inhibitors in Locally Advanced Breast Cancer: An Evidence-Based Review on Current Options
Giulia Grizzi, Michele Ghidini, Andrea Botticelli, Gianluca Tomasello, Antonio Ghidini, Francesco Grossi, Nicola Fusco, Mary Cabiddu, Tommaso Savio & Fausto Petrelli
Pages: 675-686
Published online: 30 Jan 2020
AbstractforStrategies for Increasing the Effectiveness of Aromatase Inhibitors in Locally Advanced Breast Cancer: An Evidence-Based Review on Current Options | Full Text | References | PDF (580.4 KB) | EPUB
  • 202 Views
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Article
LncRNA LEF1-AS1 Promotes Ovarian Cancer Development Through Interacting with miR-1285-3p
Yanan Zhang & Fang Ruan
Pages: 687-694
Published online: 30 Jan 2020
AbstractforLncRNA LEF1-AS1 Promotes Ovarian Cancer Development Through Interacting with miR-1285-3p | Full Text | References | PDF (6.1 MB) | EPUB
  • 99 Views
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Review

Review Article
The Anti-Cancer Mechanisms of Berberine: A Review
Ye Wang, Yanfang Liu, Xinyang Du, Hong Ma & Jing Yao
Pages: 695-702
Published online: 30 Jan 2020
AbstractforThe Anti-Cancer Mechanisms of Berberine: A Review | Full Text | References | PDF (1.6 MB) | EPUB
  • 1885 Views
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Article
EGFR Promotes the Development of Triple Negative Breast Cancer Through JAK/STAT3 Signaling
Xiang Song, Zhaoyun Liu & Zhiyong Yu
Pages: 703-717
Published online: 30 Jan 2020
AbstractforEGFR Promotes the Development of Triple Negative Breast Cancer Through JAK/STAT3 Signaling | Full Text | References | PDF (17.4 MB) | EPUB
  • 399 Views
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Article
Identification of Potential Prognostic Long Non-Coding RNA Biomarkers for Predicting Recurrence in Patients with Cervical Cancer
Yan Zhang, Xing Zhang, Haixia Zhu, Yang Liu, Jian Cao, Dake Li, Bo Ding, Wenjing Yan, Hua Jin & Shizhi Wang
Pages: 719-730
Published online: 31 Jan 2020
AbstractforIdentification of Potential Prognostic Long Non-Coding RNA Biomarkers for Predicting Recurrence in Patients with Cervical Cancer | Full Text | References | PDF (9.1 MB) | EPUB
  • 112 Views
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Article
Prognosis Value of Platelet Counts, Albumin and Neutrophil-Lymphocyte Ratio of Locoregional Recurrence in Patients with Operable Head and Neck Squamous Cell Carcinoma
Jing Ye, Bing Liao, Xiaohua Jiang, Zhihuai Dong, Sunhong Hu, Yuehui Liu & Mang Xiao
Pages: 731-741
Published online: 31 Jan 2020
AbstractforPrognosis Value of Platelet Counts, Albumin and Neutrophil-Lymphocyte Ratio of Locoregional Recurrence in Patients with Operable Head and Neck Squamous Cell Carcinoma | Full Text | References | PDF (3.9 MB) | EPUB
  • 126 Views
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Review

Review Article
Familial Pancreatic Cancer: Current Perspectives
Joan Llach, Sabela Carballal & Leticia Moreira
Pages: 743-758
Published online: 31 Jan 2020
AbstractforFamilial Pancreatic Cancer: Current Perspectives | Full Text | References | PDF (3.8 MB) | EPUB
  • 161 Views
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Article
The Correlation Between Computed Tomography Volumetry and Prognosis of Advanced Gastric Cancer Treated with Neoadjuvant Chemotherapy
Chao Chen, Hao Dong, Chunhui Shou, Xiaoxiao Shi, Qing Zhang, Xiaosun Liu, Kankai Zhu, Baishu Zhong & Jiren Yu
Pages: 759-768
Published online: 03 Feb 2020
AbstractforThe Correlation Between Computed Tomography Volumetry and Prognosis of Advanced Gastric Cancer Treated with Neoadjuvant Chemotherapy | Full Text | References | PDF (3.5 MB) | EPUB
  • 76 Views
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Article
High Expression of CD44 Predicts a Poor Prognosis in Glioblastomas
Daolin Si, Fei Yin, Jing Peng & Guangying Zhang
Pages: 769-775
Published online: 03 Feb 2020
AbstractforHigh Expression of CD44 Predicts a Poor Prognosis in Glioblastomas | Full Text | References | PDF (698 KB) | EPUB
  • 157 Views
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Clinical Trial Report

Case Report
Feasibility Study of Adjuvant Chemotherapy with Carboplatin and Nab-Paclitaxel for Completely Resected NSCLC
Naoko Katsurada, Motoko Tachihara, Yukihisa Hatakeyama, Kiyoko Koyama, Masako Yumura, Tatsunori Kiriu, Ryota Dokuni, Daisuke Hazama, Shuntaro Tokunaga, Daisuke Tamura, Kyosuke Nakata, Masatsugu Yamamoto, Hiroshi Kamiryo, Kazuyuki Kobayashi, Yugo Tanaka, Yoshimasa Maniwa & Yoshihiro Nishimura
Pages: 777-782
Published online: 03 Feb 2020
AbstractforFeasibility Study of Adjuvant Chemotherapy with Carboplatin and Nab-Paclitaxel for Completely Resected NSCLC | Full Text | References | PDF (697.2 KB) | EPUB
  • 63 Views
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Article
Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML
Guangfu Mu & Fangping Chen
Pages: 783-792
Published online: 04 Feb 2020
AbstractforOncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML | Full Text | References | PDF (5.9 MB) | EPUB
  • 81 Views
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Article
Mediation Analysis Reveals Potential Biological Mechanism of Ascites Influencing Recurrence in Patients with Epithelial Ovarian Cancer
Chunyan Yang, Ce Wang, Zhiwei Rong, Zhenyi Xu, Kui Deng, Weiwei Zhao, Lei Cao, Yaxin Lu, Humara Adnan, Kang Li & Yan Hou
Pages: 793-799
Published online: 04 Feb 2020
AbstractforMediation Analysis Reveals Potential Biological Mechanism of Ascites Influencing Recurrence in Patients with Epithelial Ovarian Cancer | Full Text | References | PDF (787.8 KB) | EPUB
  • 76 Views
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Article
The Double-Edge Role of the Addition of Adjuvant Chemotherapy to Concurrent Chemoradiotherapy in the Treatment of Nasopharyngeal Carcinoma
Zhong-Guo Liang, Fan Zhang, Bin-Bin Yu, Ling Li, Song Qu, Ye Li, Ying Guan, Ren-Ba Liang, Lu Han & Xiao-Dong Zhu
Pages: 801-812
Published online: 04 Feb 2020
AbstractforThe Double-Edge Role of the Addition of Adjuvant Chemotherapy to Concurrent Chemoradiotherapy in the Treatment of Nasopharyngeal Carcinoma | Full Text | References | PDF (4.4 MB) | EPUB
  • 59 Views
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Review

Review Article
Controversies Regarding Ovarian Suppression and Infertility in Early Stage Breast Cancer
Sajid Durrani & Humariya Heena
Pages: 813-817
Published online: 05 Feb 2020
AbstractforControversies Regarding Ovarian Suppression and Infertility in Early Stage Breast Cancer | Full Text | References | PDF (309.8 KB) | EPUB
  • 129 Views
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Article
The Significance of miRNAs as a Prognostic Biomarker for Survival Outcome in T Cell – Acute Lymphoblastic Leukemia Patients: A Systematic Review and Meta-Analysis
Shanthi Sabarimurugan, Chellan Kumarasamy, Madurantakam Royam Madhav, Suja Samiappan & Rama Jayaraj
Pages: 819-839
Published online: 05 Feb 2020
AbstractforThe Significance of miRNAs as a Prognostic Biomarker for Survival Outcome in T Cell – Acute Lymphoblastic Leukemia Patients: A Systematic Review and Meta-Analysis | Full Text | References | PDF (10.7 MB) | EPUB
  • 116 Views
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Article
Circulating Tumor Cells as a Biomarker to Assist Molecular Diagnosis for Early Stage Non-Small Cell Lung Cancer
Yutong He, Jin Shi, Bernd Schmidt, Qingyi Liu, Gaofeng Shi, Xiaoli Xu, Congmin Liu, Zhaoyu Gao, Tiantian Guo & Baoen Shan
Pages: 841-854
Published online: 05 Feb 2020
AbstractforCirculating Tumor Cells as a Biomarker to Assist Molecular Diagnosis for Early Stage Non-Small Cell Lung Cancer | Full Text | References | PDF (2.6 MB) | EPUB
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Article
LINC01410 Knockdown Suppresses Cervical Cancer Growth and Invasion via Targeting miR-2467-3p/VOPP1 Axis
Fengjuan Liu & Chuansong Wen
Pages: 855-861
Published online: 05 Feb 2020
AbstractforLINC01410 Knockdown Suppresses Cervical Cancer Growth and Invasion via Targeting miR-2467-3p/VOPP1 Axis | Full Text | References | PDF (5 MB) | EPUB
  • 78 Views
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Article
Hepatic Arterial Infusion Oxaliplatin Plus Oral S-1 Chemotherapy in Gastric Cancer with Unresectable Liver Metastases: A Case Series and Literature Review
Kangxin Wang, Xuebin Zhang, Jia Wei, Yiwen Xu, Qin Liu, Jiaqi Xie, Lihua Yuan, Zhichen Sun, Siyi Tan, Lianru Zhang, Baorui Liu & Yang Yang
Pages: 863-870
Published online: 07 Feb 2020
AbstractforHepatic Arterial Infusion Oxaliplatin Plus Oral S-1 Chemotherapy in Gastric Cancer with Unresectable Liver Metastases: A Case Series and Literature Review | Full Text | References | PDF (2.4 MB) | EPUB
  • 70 Views
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Article
Associations Between miRNAs and Two Different Cancers: Breast and Colon
Berrin Papila Kundaktepe, Volkan Sozer, Cigdem Papila, Sinem Durmus, Pinar Cigdem Kocael, Gonul Simsek, Remise Gelisgen, Kagan Zengin, Kenan Ulualp & Hafize Uzun
Pages: 871-879
Published online: 07 Feb 2020
AbstractforAssociations Between miRNAs and Two Different Cancers: Breast and Colon | Full Text | References | PDF (388.9 KB) | EPUB
  • 69 Views
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Article
A New Nomogram Based on Early Postoperative NLR for Predicting Infectious Complications After Gastrectomy
Chen Wang, Han-zhang Huang, Yu He, Yu-jun Yu, Qing-miao Zhou, Rong-jian Wang, Jian-bo He & Shao-liang Han
Pages: 881-889
Published online: 07 Feb 2020
AbstractforA New Nomogram Based on Early Postoperative NLR for Predicting Infectious Complications After Gastrectomy | Full Text | References | PDF (1.6 MB) | EPUB
  • 64 Views
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Article
The Prognostic Value of Body Fat Components in Metastasis Renal Cell Carcinoma Patients Treated with TKIs
Jindong Dai, Xingming Zhang, Zhenhua Liu, Tingni Song, Xudong Zhu, Haoran Zhang, Mingpeng Wu, Xiang Li, Hao Zeng & Pengfei Shen
Pages: 891-903
Published online: 07 Feb 2020
AbstractforThe Prognostic Value of Body Fat Components in Metastasis Renal Cell Carcinoma Patients Treated with TKIs | Full Text | References | PDF (4.3 MB) | EPUB
  • 72 Views
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Article
A Study on the Psychological Factors Affecting the Quality of Life Among Ovarian Cancer Patients in China
Zhi-Hui Gu, Tian Qiu, Shi-Han Yang, Fang-Qiong Tian & Hui Wu
Pages: 905-912
Published online: 07 Feb 2020
AbstractforA Study on the Psychological Factors Affecting the Quality of Life Among Ovarian Cancer Patients in China | Full Text | References | PDF (331.6 KB) | EPUB
  • 251 Views
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Article
Recurrence Patterns and Survival Outcomes in Chinese Patients with Surgically Treated Recurrent Ovarian Clear Cell Carcinoma: A Single Institutional Analysis of 45 Cases
Shuang Ye, Shuling Zhou, Wei Chen, Libing Xiang, Xiaohua Wu & Huijuan Yang
Pages: 913-919
Published online: 07 Feb 2020
AbstractforRecurrence Patterns and Survival Outcomes in Chinese Patients with Surgically Treated Recurrent Ovarian Clear Cell Carcinoma: A Single Institutional Analysis of 45 Cases | Full Text | References | PDF (1.1 MB) | EPUB
  • 91 Views
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Article
CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1
Yunfei Liu, Li Xia, Luo Dong, Jiale Wang, Qiangsheng Xiao, Xiao Yu & Hongwei Zhu
Pages: 921-929
Published online: 11 Feb 2020
AbstractforCircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1 | Full Text | References | PDF (6.4 MB) | EPUB
  • 96 Views
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Review

Review Article
Anesthetic Strategies in Oncological Surgery: Not Only a Simple Sleep, but Also Impact on Immunosuppression and Cancer Recurrence
Federico Longhini, Andrea Bruni, Eugenio Garofalo, Rosalba De Sarro, Riccardo Memeo, Paolo Navalesi, Giuseppe Navarra, Girolamo Ranieri, Giuseppe Currò & Michele Ammendola
Pages: 931-940
Published online: 10 Feb 2020
AbstractforAnesthetic Strategies in Oncological Surgery: Not Only a Simple Sleep, but Also Impact on Immunosuppression and Cancer Recurrence | Full Text | References | PDF (1.4 MB) | EPUB
  • 278 Views
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Article
Comparison of chemoembolization with CalliSpheres® microspheres and conventional chemoembolization in the treatment of hepatocellular carcinoma: a multicenter retrospective study
Bin Liang, Hua Xiang, Cong Ma, Bin Xiong, Yilong Ma, Chang Zhao, Yuanhui Yao, Zishu Zhang, Changyong Chen, Haiping Li, Qingyun Long, Jun Zhou, Chao Luo, Huaiming Qiu, Hongyao Hu, Hui Zhao, Guofeng Zhou & Chuansheng Zheng
Pages: 941-956
Published online: 10 Feb 2020
AbstractforComparison of chemoembolization with CalliSpheres® microspheres and conventional chemoembolization in the treatment of hepatocellular carcinoma: a multicenter retrospective study | Full Text | References | PDF (3.6 MB) | EPUB
  • 123 Views
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Review

Review Article
Management of Chemotherapy for Stage II Nasopharyngeal Carcinoma in the Intensity-Modulated Radiotherapy Era: A Review
Peng Wu, Yumei Zhao, Li Xiang & Linglin Yang
Pages: 957-963
Published online: 10 Feb 2020
AbstractforManagement of Chemotherapy for Stage II Nasopharyngeal Carcinoma in the Intensity-Modulated Radiotherapy Era: A Review | Full Text | References | PDF (299.2 KB) | EPUB
  • 87 Views
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Article
A New Model Incorporating Axillary Ultrasound After Neoadjuvant Chemotherapy to Predict Non-Sentinel Lymph Node Metastasis in Invasive Breast Cancer
Kai Zhang, Qian Zhu, Danli Sheng, Jiawei Li & Cai Chang
Pages: 965-972
Published online: 10 Feb 2020
AbstractforA New Model Incorporating Axillary Ultrasound After Neoadjuvant Chemotherapy to Predict Non-Sentinel Lymph Node Metastasis in Invasive Breast Cancer | Full Text | References | PDF (888 KB) | EPUB
  • 71 Views
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Article
MicroRNA-146a as a Prognostic Biomarker for Esophageal Squamous Cell Carcinoma
Maryam Sadegh Shesh Poli, Safoura Khajeniazi, Nasser Behnampour, Mohammad Reza Kalani, Abdolvahab Moradi & Abdoljalal Marjani
Pages: 973-980
Published online: 11 Feb 2020
AbstractforMicroRNA-146a as a Prognostic Biomarker for Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (3.4 MB) | EPUB
  • 79 Views
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Article
Heat Shock Cognate Protein 70 Enhanced Integrin β1 Mediated Invasion in Cancer Cells
Guan Sun, Ying Cao, Jun Guo, Min Li & Yuyu Dai
Pages: 981-991
Published online: 11 Feb 2020
AbstractforHeat Shock Cognate Protein 70 Enhanced Integrin β1 Mediated Invasion in Cancer Cells | Full Text | References | PDF (7.4 MB) | EPUB
  • 72 Views
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Article
Knowledge, Attitude and Practice Towards Cervical Cancer Screening Among Women and Associated Factors in Hospitals of Wolaita Zone, Southern Ethiopia
Tadesse Tekle, Eskinder Wolka, Banchialem Nega, Wondimagegn Paulos Kumma & Mengistu Meskele Koyira
Pages: 993-1005
Published online: 11 Feb 2020
AbstractforKnowledge, Attitude and Practice Towards Cervical Cancer Screening Among Women and Associated Factors in Hospitals of Wolaita Zone, Southern Ethiopia | Full Text | References | PDF (360.9 KB) | EPUB
  • 1681 Views
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Article
IGFBP-3 Is the Key Target of Sanguinarine in Promoting Apoptosis in Hepatocellular Carcinoma
Huiwen Wang, He Wang, Kai Li, Shijie Li & Bingyi Sun
Pages: 1007-1015
Published online: 11 Feb 2020
AbstractforIGFBP-3 Is the Key Target of Sanguinarine in Promoting Apoptosis in Hepatocellular Carcinoma | Full Text | References | PDF (4.5 MB) | EPUB
  • 94 Views
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Article
RETRACTED ARTICLE: Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens
Feng Xu, Dong Wang, JianXiu Cui, Jie Li & Hongchuan Jiang
Pages: 1017-1027
Published online: 11 Feb 2020
AbstractforRETRACTED ARTICLE: Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens | PDF (4 MB)
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Article
Usefulness of Inflammation-Based Prognostic Scores for Predicting the Risk of Complications After Radical Resection of Colorectal Carcinoma
Wenhao Man, Huajun Lin, Zhao Liu, Lei Jin, Jin Wang, Jun Zhang, Zhigang Bai, Hongwei Yao, Zhongtao Zhang & Wei Deng
Pages: 1029-1038
Published online: 11 Feb 2020
AbstractforUsefulness of Inflammation-Based Prognostic Scores for Predicting the Risk of Complications After Radical Resection of Colorectal Carcinoma | Full Text | References | PDF (2.2 MB) | EPUB
  • 77 Views
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Article
The Cost of Bottling It Up: Emotion Suppression as a Mediator in the Relationship Between Anger and Depression Among Men with Prostate Cancer
Simon M Rice, David Kealy, John S Ogrodniczuk, Zac E Seidler, Linda Denehy & John L Oliffe
Pages: 1039-1046
Published online: 11 Feb 2020
AbstractforThe Cost of Bottling It Up: Emotion Suppression as a Mediator in the Relationship Between Anger and Depression Among Men with Prostate Cancer | Full Text | References | PDF (506.4 KB) | EPUB
  • 472 Views
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Article
The Role of Prognostic Factors in Salivary Gland Tumors Treated by Surgery and Adjuvant Radio- or Chemoradiotherapy – A Single Institution Experience
Izabela Kordzińska-Cisek, Paweł Cisek & Ludmiła Grzybowska-Szatkowska
Pages: 1047-1067
Published online: 11 Feb 2020
AbstractforThe Role of Prognostic Factors in Salivary Gland Tumors Treated by Surgery and Adjuvant Radio- or Chemoradiotherapy – A Single Institution Experience | Full Text | References | PDF (712.6 KB) | EPUB
  • 106 Views
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Article
Effects of Topical Hangeshashinto (TJ-14) on Chemotherapy-Induced Oral Mucositis
Natsuo Ozawa, Takeshi Onda, Kamichika Hayashi, Hirona Honda & Takahiko Shibahara
Pages: 1069-1078
Published online: 12 Feb 2020
AbstractforEffects of Topical Hangeshashinto (TJ-14) on Chemotherapy-Induced Oral Mucositis | Full Text | References | PDF (2.9 MB) | EPUB
  • 149 Views
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Review

Review Article
The Emerging Roles of miR-125b in Cancers
Ying Wang, Guilin Zeng & Yicheng Jiang
Pages: 1079-1088
Published online: 12 Feb 2020
AbstractforThe Emerging Roles of miR-125b in Cancers | Full Text | References | PDF (948.4 KB) | EPUB
  • 213 Views
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Original Research

Article
Effects of Nicotinamide on Cervical Cancer-Derived Fibroblasts: Evidence for Therapeutic Potential
Reem N Hassan, Hualei Luo & Weiying Jiang
Pages: 1089-1100
Published online: 12 Feb 2020
AbstractforEffects of Nicotinamide on Cervical Cancer-Derived Fibroblasts: Evidence for Therapeutic Potential | Full Text | References | PDF (8.5 MB) | EPUB
  • 105 Views
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Article
The Incidence Rate of Liver Cancer in Saudi Arabia: An Observational Descriptive Epidemiological Analysis of Data from the Saudi Cancer Registry (2004–2014)
Ibrahim G Alghamdi & Mohamed S Alghamdi
Pages: 1101-1111
Published online: 13 Feb 2020
AbstractforThe Incidence Rate of Liver Cancer in Saudi Arabia: An Observational Descriptive Epidemiological Analysis of Data from the Saudi Cancer Registry (2004–2014) | Full Text | References | PDF (2.7 MB) | EPUB
  • 212 Views
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Article
Long Noncoding RNA RP11-334E6.12 Promotes the Proliferation, Migration and Invasion of Breast Cancer Cells Through the EMT Pathway by Activating the STAT3 Cascade
Dongjun Sun, Hengming Liu & Tiantian Wang
Pages: 1113-1120
Published online: 13 Feb 2020
AbstractforLong Noncoding RNA RP11-334E6.12 Promotes the Proliferation, Migration and Invasion of Breast Cancer Cells Through the EMT Pathway by Activating the STAT3 Cascade | Full Text | References | PDF (6.9 MB) | EPUB
  • 65 Views
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Article
Full-Core Biopsy Systems Take Larger Liver Tissue Samples with Lower Fragmentation Rates Than Conventional Side-Notch Systems: A Randomized Trial
Jan Schaible, Kirsten Utpatel, Niklas Verloh, Ingo Einspieler, Benedikt Pregler, Florian Zeman, Philipp Wiggermann, Andreas G Schreyer, Christian Stroszczynski & Lukas P Beyer
Pages: 1121-1128
Published online: 13 Feb 2020
AbstractforFull-Core Biopsy Systems Take Larger Liver Tissue Samples with Lower Fragmentation Rates Than Conventional Side-Notch Systems: A Randomized Trial | Full Text | References | PDF (2.5 MB) | EPUB
  • 73 Views
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Article
LncRNA HCP5 Stimulates the Proliferation of Non-Small Cell Lung Cancer Cells by Up-Regulating Survivin Through the Down-Regulation of miR-320
Chao Li, Zhang Lei, Bin Peng, Jiang Zhu & Li Chen
Pages: 1129-1134
Published online: 14 Feb 2020
AbstractforLncRNA HCP5 Stimulates the Proliferation of Non-Small Cell Lung Cancer Cells by Up-Regulating Survivin Through the Down-Regulation of miR-320 | Full Text | References | PDF (1.8 MB) | EPUB
  • 56 Views
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Article
lncRNA ZFAS1 Is Involved in the Proliferation, Invasion and Metastasis of Prostate Cancer Cells Through Competitively Binding to miR-135a-5p
Jiaqiang Pan, Xingyan Xu & Guangliang Wang
Pages: 1135-1149
Published online: 13 Feb 2020
AbstractforlncRNA ZFAS1 Is Involved in the Proliferation, Invasion and Metastasis of Prostate Cancer Cells Through Competitively Binding to miR-135a-5p | Full Text | References | PDF (12.8 MB) | EPUB
  • 80 Views
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Article
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro
Wei Yu, Dulei Xiang, Houjun Jia, Xin He, Jie Sheng, Yuxiang Long, Shujuan Zhu, Kejian Wang & Qian Liu
Pages: 1151-1161
Published online: 13 Feb 2020
AbstractforThe lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro | Full Text | References | PDF (7.9 MB) | EPUB
  • 79 Views
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Article
Cancer Patient-Reported Preferences and Knowledge for Liquid Biopsies and Blood Biomarkers at a Comprehensive Cancer Center
Min Joon Lee, Katrina Hueniken, Nathan Kuehne, Lin Lu, Shirley Xue Jiang, Badr Id Said, Alex McCartney, Yizhuo Gao, Mindy Liang, Tamara Obuobi, Hadas Sorotsky, Lawson Eng, M Catherine Brown, Wei Xu & Geoffrey Liu
Pages: 1163-1173
Published online: 13 Feb 2020
AbstractforCancer Patient-Reported Preferences and Knowledge for Liquid Biopsies and Blood Biomarkers at a Comprehensive Cancer Center | Full Text | References | PDF (1.1 MB) | EPUB
  • 175 Views
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Article
Cardiotoxic Profile and Arterial Stiffness of Adjuvant Chemotherapy for Colorectal Cancer
A Visvikis, SM Kyvelou, P Pietri, C Georgakopoulos, K Manousou, D Tousoulis, C Stefanadis, C Vlachopoulos & D Pektasides
Pages: 1175-1185
Published online: 13 Feb 2020
AbstractforCardiotoxic Profile and Arterial Stiffness of Adjuvant Chemotherapy for Colorectal Cancer | Full Text | References | PDF (876.7 KB) | EPUB
  • 90 Views
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Article
Regulation of E2F Transcription Factor 3 by microRNA-152 Modulates Gastric Cancer Invasion and Metastasis
Liangliang Shi, Hao Zhu, Yonghua Shen, Xiaotan Dou, Huimin Guo, Pin Wang, Shu Zhang, Lin Zhou & Xiaoping Zou
Pages: 1187-1197
Published online: 14 Feb 2020
AbstractforRegulation of E2F Transcription Factor 3 by microRNA-152 Modulates Gastric Cancer Invasion and Metastasis | Full Text | References | PDF (9.3 MB) | EPUB
  • 81 Views
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Article
Heavy Water Affects Vital Parameters of Human Melanoma Cells in vitro
Johannes Kleemann, Gabi Reichenbach, Nadja Zöller, Manuel Jäger, Roland Kaufmann, Markus Meissner & Stefan Kippenberger
Pages: 1199-1209
Published online: 17 Feb 2020
AbstractforHeavy Water Affects Vital Parameters of Human Melanoma Cells in vitro | Full Text | References | PDF (17.7 MB) | EPUB
  • 106 Views
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Article
Contrast-Enhanced CT Parameters of Gastric Adenocarcinoma: Can Radiomic Features Be Surrogate Biomarkers for HER2 Over-Expression Status?
Na Wang, Xinxin Wang, Wenya Li, Huajun Ye, Hongzhao Bai, Jiansheng Wu & Mengjun Chen
Pages: 1211-1219
Published online: 18 Feb 2020
AbstractforContrast-Enhanced CT Parameters of Gastric Adenocarcinoma: Can Radiomic Features Be Surrogate Biomarkers for HER2 Over-Expression Status? | Full Text | References | PDF (952.1 KB) | EPUB
  • 68 Views
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Article
LncRNA DCST1-AS1 Was Upregulated in Endometrial Carcinoma and May Sponge miR-92a-3p to Upregulate Notch1
Jieqi Ke, Zheng Shen, Weiping Hu, Min Li, Yangyang Shi, Zhen Xie & Dabao Wu
Pages: 1221-1227
Published online: 18 Feb 2020
AbstractforLncRNA DCST1-AS1 Was Upregulated in Endometrial Carcinoma and May Sponge miR-92a-3p to Upregulate Notch1 | Full Text | References | PDF (3.2 MB) | EPUB
  • 84 Views
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Article
circPVT1 Facilitates Invasion and Metastasis by Regulating miR-205-5p/c-FLIP Axis in Osteosarcoma
Yu-Peng Liu, Jun Wan, Feng Long, Jian Tian & Can Zhang
Pages: 1229-1240
Published online: 18 Feb 2020
AbstractforcircPVT1 Facilitates Invasion and Metastasis by Regulating miR-205-5p/c-FLIP Axis in Osteosarcoma | Full Text | References | PDF (8.8 MB) | EPUB
  • 94 Views
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Article
Matrine Restrains Cell Growth and Metastasis by Up-Regulating LINC00472 in Bladder Carcinoma
Linlin Li, Fei Qi & Kaichen Wang
Pages: 1241-1251
Published online: 18 Feb 2020
AbstractforMatrine Restrains Cell Growth and Metastasis by Up-Regulating LINC00472 in Bladder Carcinoma | Full Text | References | PDF (7.2 MB) | EPUB
  • 67 Views
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Article
Alteration in Expression of miR-32 and FBXW7 Tumor Suppressor in Plasma Samples of Patients with T-cell Acute Lymphoblastic Leukemia
Sanaz Mansouri, Behzad Khansarinejad, Ghasem Mosayebi, Aziz Eghbali & Mahdieh Mondanizadeh
Pages: 1253-1259
Published online: 18 Feb 2020
AbstractforAlteration in Expression of miR-32 and FBXW7 Tumor Suppressor in Plasma Samples of Patients with T-cell Acute Lymphoblastic Leukemia | Full Text | References | PDF (1.6 MB) | EPUB
  • 69 Views
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Article
Long Non-Coding RNA TMPO-AS1 Promotes Cell Migration and Invasion by Sponging miR-140-5p and Inducing SOX4-Mediated EMT in Gastric Cancer
Yonghong Sun & Chunyao Han
Pages: 1261-1268
Published online: 20 Feb 2020
AbstractforLong Non-Coding RNA TMPO-AS1 Promotes Cell Migration and Invasion by Sponging miR-140-5p and Inducing SOX4-Mediated EMT in Gastric Cancer | Full Text | References | PDF (6.5 MB) | EPUB
  • 73 Views
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Article
The Significance of Negative Lymph Nodes in Esophageal Cancer After Curative Resection: A Retrospective Cohort Study
Junxian Mo, Dongni Chen, Changbo Li & Mingwu Chen
Pages: 1269-1279
Published online: 20 Feb 2020
AbstractforThe Significance of Negative Lymph Nodes in Esophageal Cancer After Curative Resection: A Retrospective Cohort Study | Full Text | References | PDF (3 MB) | EPUB
  • 79 Views
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Article
RETRACTED ARTICLE: Long Non-Coding RNA Cancer Susceptibility 9 (CASC9) Up-Regulates the Expression of ERBB2 by Inhibiting miR-193a-5p in Colorectal Cancer
Yuansheng Ding, Xiaoyan Li, Yucui Zhang & Jie Zhang
Pages: 1281-1292
Published online: 20 Feb 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA Cancer Susceptibility 9 (CASC9) Up-Regulates the Expression of ERBB2 by Inhibiting miR-193a-5p in Colorectal Cancer | PDF (8.1 MB)
  • 18 Views
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Article
Validation of the EUTOS Long-Term Survival Score in Chinese Chronic Myeloid Leukemia Patients Treated with Imatinib: A Multicenter Real-World Study
Xiawan Yang, Yanliang Bai, Mingyue Shi, Wanjun Zhang, Junwei Niu, Chengye Wu, Lei Zhang, Zhiwei Xu, Xiang Liu, Yuqing Chen & Kai Sun
Pages: 1293-1301
Published online: 20 Feb 2020
AbstractforValidation of the EUTOS Long-Term Survival Score in Chinese Chronic Myeloid Leukemia Patients Treated with Imatinib: A Multicenter Real-World Study | Full Text | References | PDF (6 MB) | EPUB
  • 100 Views
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Article
Peripheral Blood Platelet–Lymphocyte Ratio Is Good Predictor of Chemosensitivity and Prognosis in Gastric Cancer Patients
Yuka Ohe, Sachio Fushida, Takahisa Yamaguchi, Jun Kinoshita, Hiroto Saito, Koichi Okamoto, Keishi Nakamura, Hidehiro Tajima, Itasu Ninomiya & Tetsuo Ohta
Pages: 1303-1311
Published online: 20 Feb 2020
AbstractforPeripheral Blood Platelet–Lymphocyte Ratio Is Good Predictor of Chemosensitivity and Prognosis in Gastric Cancer Patients | Full Text | References | PDF (2 MB) | EPUB
  • 94 Views
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Article
Knocking Out SST Gene of BGC823 Gastric Cancer Cell by CRISPR/Cas9 Enhances Migration, Invasion and Expression of SEMA5A and KLF2
Wei Chen, Ruixian Ding, Jinlu Tang, Haodong Li, Chonghua Chen, Yaru Zhang, Qinxian Zhang & Xiaoyan Zhu
Pages: 1313-1321
Published online: 20 Feb 2020
AbstractforKnocking Out SST Gene of BGC823 Gastric Cancer Cell by CRISPR/Cas9 Enhances Migration, Invasion and Expression of SEMA5A and KLF2 | Full Text | References | PDF (6.2 MB) | EPUB
  • 97 Views
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Article
Clinical Study on Prelaryngeal Lymph Node Metastasis in Papillary Thyroid Carcinoma
Jin-Xing Gong, Jian-Wei Gu, Feng Ji, Kun Li, Qi Zhu, Fang-Ying Gu, Yan Chen & Qing-Hai Ji
Pages: 1323-1327
Published online: 21 Feb 2020
AbstractforClinical Study on Prelaryngeal Lymph Node Metastasis in Papillary Thyroid Carcinoma | Full Text | References | PDF (210.6 KB) | EPUB
  • 81 Views
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Article
Long-Term Survival After Nasopharyngeal Carcinoma Treatment in a Local Prefecture-Level Hospital in Southern China
Yun Du, Wentong Zhang, Feng Lei, Xia Yu, Zhuming Li, Xiaodong Liu, Yanan Ni, Li Deng & Mingfang Ji
Pages: 1329-1338
Published online: 24 Feb 2020
AbstractforLong-Term Survival After Nasopharyngeal Carcinoma Treatment in a Local Prefecture-Level Hospital in Southern China | Full Text | References | PDF (1.6 MB) | EPUB
  • 87 Views
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Article
Safety and Efficacy of PD-1 Inhibitors Plus Chemotherapy in Advanced Soft Tissue Sarcomas: A Retrospective Study
Zhichao Tian, Yonghao Yang, Jinpo Yang, Peng Zhang, Fan Zhang, Xinhui Du, Chao Li & Jiaqiang Wang
Pages: 1339-1346
Published online: 24 Feb 2020
AbstractforSafety and Efficacy of PD-1 Inhibitors Plus Chemotherapy in Advanced Soft Tissue Sarcomas: A Retrospective Study | Full Text | References | PDF (1.6 MB) | EPUB
  • 317 Views
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Article
Clinicopathological Characteristics and Treatment Outcomes of Pregnancy Complicated by Malignant Ovarian Germ Cell Tumors
Xuan Zong, Jia-Xin Yang, Ying Zhang, Dong-Yan Cao & Keng Shen
Pages: 1347-1354
Published online: 24 Feb 2020
AbstractforClinicopathological Characteristics and Treatment Outcomes of Pregnancy Complicated by Malignant Ovarian Germ Cell Tumors | Full Text | References | PDF (298.6 KB) | EPUB
  • 96 Views
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Article
Free Fatty Acids Promote the Development of Prostate Cancer by Upregulating Peroxisome Proliferator-Activated Receptor Gamma
Xiaodan Ha, Jingzhou Wang, Keru Chen, Yuchun Deng, Xueting Zhang, Jiale Feng, Xue Li, Jiaojiao Zhu, Yinghua Ma, Tongtong Qiu, Cuizhe Wang, Jianxin Xie & Jun Zhang
Pages: 1355-1369
Published online: 24 Feb 2020
AbstractforFree Fatty Acids Promote the Development of Prostate Cancer by Upregulating Peroxisome Proliferator-Activated Receptor Gamma | Full Text | References | PDF (6.1 MB) | EPUB
  • 138 Views
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Corrigendum

Correction
The Development of a Nomogram to Predict Post-Radiation Necrosis in Nasopharyngeal Carcinoma Patients: A Large-Scale Cohort Study [Corrigendum]
Page: 1371
Published online: 25 Feb 2020
CitationforThe Development of a Nomogram to Predict Post-Radiation Necrosis in Nasopharyngeal Carcinoma Patients: A Large-Scale Cohort Study [Corrigendum] | Full Text | PDF (146 KB) | EPUB
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Original Research

Article
Assessment in the Survival Outcome After Transarterial Chemoembolization Combined with Cryoablation for Hepatocellular Carcinoma (Diameter > 4cm) Based on the Albumin-Bilirubin Grade and Platelet-Albumin-Bilirubin ‎grade: ‎ A Preliminary Study
Zhimei Huang, Mengxuan Zuo, Jiayan Ni, Yangkui Gu, Tianqi Zhang, Yiquan Jiang, Shuiqing Zhuo, Chao An & Jinhua Huang
Pages: 1373-1385
Published online: 25 Feb 2020
AbstractforAssessment in the Survival Outcome After Transarterial Chemoembolization Combined with Cryoablation for Hepatocellular Carcinoma (Diameter > 4cm) Based on the Albumin-Bilirubin Grade and Platelet-Albumin-Bilirubin ‎grade: ‎ A Preliminary Study | Full Text | References | PDF (3.5 MB) | EPUB
  • 97 Views
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Article
Oral Maintenance Chemotherapy Using S-1/Capecitabine in Metastatic Nasopharyngeal Carcinoma Patients After Systemic Chemotherapy: A Single-Institution Experience
Qiaojuan Guo, Mengwei Chen, Hanchuan Xu, Tianzhu Lu, Han Zhou, Yanyan Chen, Jingfeng Zong, Yun Xu, Bijuan Chen, Bingyi Wang, Lili Zhu, Jianji Pan & Shaojun Lin
Pages: 1387-1396
Published online: 25 Feb 2020
AbstractforOral Maintenance Chemotherapy Using S-1/Capecitabine in Metastatic Nasopharyngeal Carcinoma Patients After Systemic Chemotherapy: A Single-Institution Experience | Full Text | References | PDF (3.2 MB) | EPUB
  • 87 Views
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Article
Clinical Features and Prognostic Factor of Thoracic Postoperative Oligo-Recurrence of Non-Small-Cell Lung Cancer
Qi Yuan, Wei Wang, Qian Zhang, Yuchao Wang, Chuanzhen Chi & Chunhua Xu
Pages: 1397-1403
Published online: 25 Feb 2020
AbstractforClinical Features and Prognostic Factor of Thoracic Postoperative Oligo-Recurrence of Non-Small-Cell Lung Cancer | Full Text | References | PDF (690.9 KB) | EPUB
  • 86 Views
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Article
Validation of the 2018 FIGO Staging System of Cervical Cancer for Stage III Patients with a Cohort from China
Xiaoliang Liu, Junjie Wang, Ke Hu, Fuquan Zhang, Qingyu Meng, Weiping Wang, Dunhuang Wang, Ziqi Zhou & Kang Ren
Pages: 1405-1410
Published online: 25 Feb 2020
AbstractforValidation of the 2018 FIGO Staging System of Cervical Cancer for Stage III Patients with a Cohort from China | Full Text | References | PDF (1.1 MB) | EPUB
  • 108 Views
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Review

Review Article
Bone Metastases of Gastrointestinal Stromal Tumor: A Review of Published Literature
Jian Yang, Jijie Yan, Meihui Zeng, Wei Wan, Tielong Liu & Jian-Ru Xiao
Pages: 1411-1417
Published online: 26 Feb 2020
AbstractforBone Metastases of Gastrointestinal Stromal Tumor: A Review of Published Literature | Full Text | References | PDF (256.2 KB) | EPUB
  • 136 Views
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Original Research

Article
Pathologic Response After Weekly Paclitaxel versus Docetaxel in Operable Breast Cancer
Xenia Elena Bacinschi, Rodica Maricela Anghel, Paula Iuliana Toma, Inga Safta, Alis Ilie & Silvia Mihaela Ilie
Pages: 1419-1426
Published online: 26 Feb 2020
AbstractforPathologic Response After Weekly Paclitaxel versus Docetaxel in Operable Breast Cancer | Full Text | References | PDF (2.2 MB) | EPUB
  • 86 Views
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Article
MAGE-A11 Expression Predicts Patient Prognosis in Head and Neck Squamous Cell Carcinoma
Shiheng Jia, Minghui Zhang, Yanshu Li, Lan Zhang & Wei Dai
Pages: 1427-1435
Published online: 26 Feb 2020
AbstractforMAGE-A11 Expression Predicts Patient Prognosis in Head and Neck Squamous Cell Carcinoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 75 Views
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Article
Clinical Analysis of 15 Cases of Gallbladder Neuroendocrine Carcinoma and Comparison with Gallbladder Adenocarcinoma Using a Propensity Score Matching
Shida Yan, Yingyi Wang, Xiao Chen, Yefan Zhang, Zhen Huang, Jianjun Zhao, Jianguo Zhou, Zhiyu Li, Xinyu Bi, Zhiwen Luo, Jianqiang Cai & Hong Zhao
Pages: 1437-1446
Published online: 26 Feb 2020
AbstractforClinical Analysis of 15 Cases of Gallbladder Neuroendocrine Carcinoma and Comparison with Gallbladder Adenocarcinoma Using a Propensity Score Matching | Full Text | References | PDF (4.2 MB) | EPUB
  • 100 Views
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Article
Parity as a Prognostic Factor in Patients with Advanced-Stage Epithelial Ovarian Cancer
Abolfazl Khalafi-Nezhad, Vahid Ebrahimi, Fatemeh Ahmadpour, Mozhdeh Momtahan, Minoo Robati, Zahra Saraf, Mani Ramzi, Zahra Jowkar & Parvin Ghaffari
Pages: 1447-1456
Published online: 26 Feb 2020
AbstractforParity as a Prognostic Factor in Patients with Advanced-Stage Epithelial Ovarian Cancer | Full Text | References | PDF (352.2 KB) | EPUB
  • 90 Views
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Review

Review Article
Anti-Tumor Activities of Bioactive Phytochemicals in Sophora flavescens for Breast Cancer
Xianjiao Cao & Qingqing He
Pages: 1457-1467
Published online: 27 Feb 2020
AbstractforAnti-Tumor Activities of Bioactive Phytochemicals in Sophora flavescens for Breast Cancer | Full Text | References | PDF (378.9 KB) | EPUB
  • 215 Views
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Original Research

Article
A Hereditable Mutation of MSH2 Gene Associated with Lynch Syndrome in a Five Generation Chinese Family
Wei-Hua Shao, Cheng-Yu Wang, Lei-Yun Wang, Fan Xiao, De-Sheng Xiao, Hao Yang, Xue-Ying Long, Le Zhang, Heng-Gui Luo, Ji-Ye Yin & Wei Wu
Pages: 1469-1482
Published online: 27 Feb 2020
AbstractforA Hereditable Mutation of MSH2 Gene Associated with Lynch Syndrome in a Five Generation Chinese Family | Full Text | References | PDF (8 MB) | EPUB
  • 121 Views
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Article
miR-455-3p Functions as a Tumor Suppressor by Restraining Wnt/β-Catenin Signaling via TAZ in Pancreatic Cancer
Ting Zhan, Qingxi Zhu, Zheng Han, Jie Tan, Meng Liu, Weijie Liu, Wei Chen, Xiaoli Chen, Xueting Chen, Junsheng Deng, Xia Tian & Xiaodong Huang
Pages: 1483-1492
Published online: 27 Feb 2020
AbstractformiR-455-3p Functions as a Tumor Suppressor by Restraining Wnt/β-Catenin Signaling via TAZ in Pancreatic Cancer | Full Text | References | PDF (13.6 MB) | EPUB
  • 80 Views
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Article
RETRACTED ARTICLE: Curcumin Inhibits the Tumorigenesis of Breast Cancer by Blocking Tafazzin/Yes-Associated Protein Axis
Yuxiu Shen, Zaigang Han, Shuang Liu, Yang Jiao, Ying Li & Hongyan Yuan
Pages: 1493-1502
Published online: 27 Feb 2020
AbstractforRETRACTED ARTICLE: Curcumin Inhibits the Tumorigenesis of Breast Cancer by Blocking Tafazzin/Yes-Associated Protein Axis | PDF (7.3 MB)
  • 23 Views
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Article
OTUD4: A Potential Prognosis Biomarker for Multiple Human Cancers
Xiaohui Zhao, Xiaobo Su, Lu Cao, Tian Xie, Quan Chen, Jing Li, Rui Xu & Chao Jiang
Pages: 1503-1512
Published online: 28 Feb 2020
AbstractforOTUD4: A Potential Prognosis Biomarker for Multiple Human Cancers | Full Text | References | PDF (7.7 MB) | EPUB
  • 115 Views
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Article
Plasma Long Non-Coding RNA RP11-438N5.3 as a Novel Biomarker for Non-Small Cell Lung Cancer
Qingjuan Chen, Chenjing Zhu, Yingying Jin, Xiaomin Si, Wan Jiao, Wenjing He, Wei Mao, Ming Li & Guomin Luo
Pages: 1513-1521
Published online: 28 Feb 2020
AbstractforPlasma Long Non-Coding RNA RP11-438N5.3 as a Novel Biomarker for Non-Small Cell Lung Cancer | Full Text | References | PDF (3.9 MB) | EPUB
  • 78 Views
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Article
ICAM1 Regulates the Development of Gastric Cancer and May Be a Potential Biomarker for the Early Diagnosis and Prognosis of Gastric Cancer
Songda Chen, Shan Pan, Huijie Wu, Jingyuan Zhou, Yueli Huang, Shuai Wang & Aiqun Liu
Pages: 1523-1534
Published online: 02 Mar 2020
AbstractforICAM1 Regulates the Development of Gastric Cancer and May Be a Potential Biomarker for the Early Diagnosis and Prognosis of Gastric Cancer | Full Text | References | PDF (7 MB) | EPUB
  • 103 Views
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Article
Occurrence and Characteristics of Hospitalizations During First-Line Chemotherapy Among Individuals with Metastatic Colorectal Cancer
Michael J Fisch, Michael Grabner, Daniel S Mytelka, Amit D Raval, Lee Bowman, David M Kern, Collin Churchill, Joseph Singer, Stewart Wetmore, John Barron & Michael Eleff
Pages: 1535-1541
Published online: 03 Mar 2020
AbstractforOccurrence and Characteristics of Hospitalizations During First-Line Chemotherapy Among Individuals with Metastatic Colorectal Cancer | Full Text | References | PDF (2.4 MB) | EPUB
  • 59 Views
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Article
Pretreatment Systemic Inflammation Response Index in Patients with Breast Cancer Treated with Neoadjuvant Chemotherapy as a Useful Prognostic Indicator
Li Chen, Xiangyi Kong, Zhongzhao Wang, Xiangyu Wang, Yi Fang & Jing Wang
Pages: 1543-1567
Published online: 03 Mar 2020
AbstractforPretreatment Systemic Inflammation Response Index in Patients with Breast Cancer Treated with Neoadjuvant Chemotherapy as a Useful Prognostic Indicator | Full Text | References | PDF (425.4 KB) | EPUB
  • 156 Views
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Article
Shh Overexpression Is Correlated with GRP78 and AR Expression in Primary Prostate Cancer: Clinicopathological Features and Outcomes in a Chinese Cohort
Xiangyu Zhang, Yanmin Zhang, Fanzhong Lin, Xin Shi, Longquan Xiang & Liang Li
Pages: 1569-1578
Published online: 03 Mar 2020
AbstractforShh Overexpression Is Correlated with GRP78 and AR Expression in Primary Prostate Cancer: Clinicopathological Features and Outcomes in a Chinese Cohort | Full Text | References | PDF (7.5 MB) | EPUB
  • 73 Views
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Article
LncRNA miR503HG Regulates the Drug Resistance of Recurrent Cervical Squamous Cell Carcinoma Cells by Regulating miR-155/Caspase-3
Shanshan Zhao, Mingxin Yu & Lei Wang
Pages: 1579-1585
Published online: 03 Mar 2020
AbstractforLncRNA miR503HG Regulates the Drug Resistance of Recurrent Cervical Squamous Cell Carcinoma Cells by Regulating miR-155/Caspase-3 | Full Text | References | PDF (3.2 MB) | EPUB
  • 81 Views
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Article
Long Non-Coding RNA TMPO-AS1 Promotes Cervical Cancer Cell Proliferation, Migration, and Invasion by Regulating miR-143-3p/ZEB1 Axis
Xiaoqing Gang, Mengmeng Yuan & Juxin Zhang
Pages: 1587-1599
Published online: 03 Mar 2020
AbstractforLong Non-Coding RNA TMPO-AS1 Promotes Cervical Cancer Cell Proliferation, Migration, and Invasion by Regulating miR-143-3p/ZEB1 Axis | Full Text | References | PDF (13.3 MB) | EPUB
  • 87 Views
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Review

Review Article
The Role of Inhaled Anesthetics in Tumorigenesis and Tumor Immunity
Yichi Xu, Wenxiao Jiang, Shangdan Xie, Fang Xue & Xueqiong Zhu
Pages: 1601-1609
Published online: 04 Mar 2020
AbstractforThe Role of Inhaled Anesthetics in Tumorigenesis and Tumor Immunity | Full Text | References | PDF (933.3 KB) | EPUB
  • 126 Views
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Article
Sal‐Like Protein 4 Transcription Factor: A Significant Diagnostic Biomarker Involved in Childhood ALL Resistance and Relapse
Farzaneh Ohadi, Soheila Rahgozar & Elaheh Sadat Ghodousi
Pages: 1611-1619
Published online: 04 Mar 2020
AbstractforSal‐Like Protein 4 Transcription Factor: A Significant Diagnostic Biomarker Involved in Childhood ALL Resistance and Relapse | Full Text | References | PDF (426.3 KB) | EPUB
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Article
Perioperative Circulating Tumor DNA in Colorectal Liver Metastases: Concordance with Metastatic Tissue and Predictive Value for Tumor Burden and Prognosis
Yiping He, Xiaoji Ma, Ke Chen, Fangqi Liu, Sanjun Cai, Han Han-Zhang, Ting Hou, Jianxing Xiang & Junjie Peng
Pages: 1621-1630
Published online: 04 Mar 2020
AbstractforPerioperative Circulating Tumor DNA in Colorectal Liver Metastases: Concordance with Metastatic Tissue and Predictive Value for Tumor Burden and Prognosis | Full Text | References | PDF (5.5 MB) | EPUB
  • 113 Views
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Article
The Role of Adjuvant Chemoradiotherapy Over Radiotherapy After R0 Resection for Stage II-III Esophageal Squamous Cell Carcinoma
Tao Song, Peng Chen, Min Fang, Xuebang Zhang, Dexi Du & Shixiu Wu
Pages: 1631-1639
Published online: 05 Mar 2020
AbstractforThe Role of Adjuvant Chemoradiotherapy Over Radiotherapy After R0 Resection for Stage II-III Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (1.9 MB) | EPUB
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Article
LncRNA MIR503HG Inhibits Non-Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest Through the Downregulation of Cyclin D1
Shufen Xu, Shengping Zhai, Tiantian Du & Zhan Li
Pages: 1641-1647
Published online: 05 Mar 2020
AbstractforLncRNA MIR503HG Inhibits Non-Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest Through the Downregulation of Cyclin D1 | Full Text | References | PDF (6 MB) | EPUB
  • 73 Views
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Article
Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 Is a Potential Prognostic Biomarker and Promotes Cell Progression in Prostate Cancer
Lihua Piao, Haoyue Li, Ying Feng, Xiaogang Li, Yan Cui & Yanhua Xuan
Pages: 1649-1660
Published online: 06 Mar 2020
AbstractforLeucine Zipper-EF-Hand Containing Transmembrane Protein 1 Is a Potential Prognostic Biomarker and Promotes Cell Progression in Prostate Cancer | Full Text | References | PDF (7.6 MB) | EPUB
  • 79 Views
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Article
LncRNA NCK1-AS1 Promotes Cancer Cell Proliferation and Increase Cell Stemness in Urinary Bladder Cancer Patients by Downregulating miR-143
Zhongjie Qiao, Hongshuang Dai, Yunzhu Zhang, Qiang Li, Meng Zhao & Tongyun Yue
Pages: 1661-1668
Published online: 06 Mar 2020
AbstractforLncRNA NCK1-AS1 Promotes Cancer Cell Proliferation and Increase Cell Stemness in Urinary Bladder Cancer Patients by Downregulating miR-143 | Full Text | References | PDF (1.9 MB) | EPUB
  • 70 Views
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Review

Review Article
Telomere Length in Renal Cell Carcinoma: The Jekyll and Hyde Biomarker of Ageing of the Kidney
Mariana Morais, Francisca Dias, Ana Luísa Teixeira & Rui Medeiros
Pages: 1669-1679
Published online: 06 Mar 2020
AbstractforTelomere Length in Renal Cell Carcinoma: The Jekyll and Hyde Biomarker of Ageing of the Kidney | Full Text | References | PDF (1.8 MB) | EPUB
  • 101 Views
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Original Research

Article
LncRNA CRNDE and lncRNA SNHG7 are Promising Biomarkers for Prognosis in Synchronous Colorectal Liver Metastasis Following Hepatectomy
Peixian Zhang, Lan Shi, Linjing Song, Yi Long, Kehua Yuan, Wanbao Ding & Lei Deng
Pages: 1681-1692
Published online: 09 Mar 2020
AbstractforLncRNA CRNDE and lncRNA SNHG7 are Promising Biomarkers for Prognosis in Synchronous Colorectal Liver Metastasis Following Hepatectomy | Full Text | References | PDF (471 KB) | EPUB
  • 69 Views
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Article
Novel Prognostic Nomograms for Predicting Early and Late Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy
Wei Xu, Ruineng Li & Fei Liu
Pages: 1693-1712
Published online: 09 Mar 2020
AbstractforNovel Prognostic Nomograms for Predicting Early and Late Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy | Full Text | References | PDF (3.5 MB) | EPUB
  • 84 Views
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Article
Fucoidan Induces Apoptosis and Inhibits Proliferation of Hepatocellular Carcinoma via the p38 MAPK/ERK and PI3K/Akt Signal Pathways
Yifei Duan, Jingjing Li, Xue Jing, Xueli Ding, Yanan Yu & Qingxi Zhao
Pages: 1713-1723
Published online: 09 Mar 2020
AbstractforFucoidan Induces Apoptosis and Inhibits Proliferation of Hepatocellular Carcinoma via the p38 MAPK/ERK and PI3K/Akt Signal Pathways | Full Text | References | PDF (8.2 MB) | EPUB
  • 248 Views
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Article
Comparison of Clinical Outcomes and Pathological Characteristics of Self-Expandable Stent Bridge to Surgery and Emergency Surgery in Obstructive Colon Cancer
Bingyan Wang, Siyi Lu, Zhiqiang Song, Fei Li, Junren Ma, Yanpeng Ma, Xin Zhou & Wei Fu
Pages: 1725-1732
Published online: 09 Mar 2020
AbstractforComparison of Clinical Outcomes and Pathological Characteristics of Self-Expandable Stent Bridge to Surgery and Emergency Surgery in Obstructive Colon Cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 84 Views
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Article
Evaluation of Contrast-Enhanced Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) in the Detection of Retropharyngeal Lymph Node Metastases in Nasopharyngeal Carcinoma Patients
Jie Chen, Jingwen Luo, Xia He & Chenjing Zhu
Pages: 1733-1739
Published online: 09 Mar 2020
AbstractforEvaluation of Contrast-Enhanced Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) in the Detection of Retropharyngeal Lymph Node Metastases in Nasopharyngeal Carcinoma Patients | Full Text | References | PDF (1.7 MB) | EPUB
  • 102 Views
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Article
Quercetin Inhibits Epithelial-to-Mesenchymal Transition (EMT) Process and Promotes Apoptosis in Prostate Cancer via Downregulating lncRNA MALAT1
Xinxing Lu, Dong Chen, Feiya Yang & Nianzeng Xing
Pages: 1741-1750
Published online: 09 Mar 2020
AbstractforQuercetin Inhibits Epithelial-to-Mesenchymal Transition (EMT) Process and Promotes Apoptosis in Prostate Cancer via Downregulating lncRNA MALAT1 | Full Text | References | PDF (3.7 MB) | EPUB
  • 186 Views
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Article
LncRNA-SNHG16 Silencing Inhibits Prostate Carcinoma Cell Growth, Downregulate GLUT1 Expression and Reduce Glucose Uptake
Mingfeng Shao, Ziqiang Yu & Jianan Zou
Pages: 1751-1757
Published online: 09 Mar 2020
AbstractforLncRNA-SNHG16 Silencing Inhibits Prostate Carcinoma Cell Growth, Downregulate GLUT1 Expression and Reduce Glucose Uptake | Full Text | References | PDF (1.1 MB) | EPUB
  • 78 Views
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Article
Impact of the Activation Status of the Akt/mTOR Signalling Pathway on the Clinical Behaviour of Synovial Sarcoma: Retrospective Analysis of 174 Patients at a Single Institution
Ying-Xue Li, Shan-Shan Ding, Wen-Juan Wen, Lin Han, Hong-Qun Wang & Huai-Yin Shi
Pages: 1759-1769
Published online: 09 Mar 2020
AbstractforImpact of the Activation Status of the Akt/mTOR Signalling Pathway on the Clinical Behaviour of Synovial Sarcoma: Retrospective Analysis of 174 Patients at a Single Institution | Full Text | References | PDF (1.9 MB) | EPUB
  • 64 Views
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Article
RETRACTED ARTICLE: Long Non-coding RNA BLACAT1 Induces Tamoxifen Resistance in Human Breast Cancer by Regulating miR-503/Bcl-2 Axis
Rongfeng Qu, Chunmei Hu, Yan Tang, Qiong Yu & Guang Shi
Pages: 1771-1777
Published online: 10 Mar 2020
AbstractforRETRACTED ARTICLE: Long Non-coding RNA BLACAT1 Induces Tamoxifen Resistance in Human Breast Cancer by Regulating miR-503/Bcl-2 Axis | PDF (4.8 MB)
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Article
Metabolically Abnormal Obesity Increases the Risk of Advanced Prostate Cancer in Chinese Patients Undergoing Radical Prostatectomy
Wen Liu, Wenxian Li, Zhankun Wang, Yao Zhu, Dingwei Ye & Guiming Zhang
Pages: 1779-1787
Published online: 10 Mar 2020
AbstractforMetabolically Abnormal Obesity Increases the Risk of Advanced Prostate Cancer in Chinese Patients Undergoing Radical Prostatectomy | Full Text | References | PDF (358.5 KB) | EPUB
  • 104 Views
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Article
AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer
Fen Xu, Yun Xu, Jian-Hui Xiong, Jing-Hui Zhang, Jian Wu, Jie Luo & Jian-Ping Xiong
Pages: 1789-1798
Published online: 10 Mar 2020
AbstractforAOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer | Full Text | References | PDF (3.9 MB) | EPUB
  • 119 Views
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Corrigendum

Correction
LncRNA TP73-AS1 Activates TGF-β1 to Promote the Migration and Invasion of Colorectal Cancer Cell [Corrigendum]
Page: 1799
Published online: 10 Mar 2020
Citationfor LncRNA TP73-AS1 Activates TGF-β1 to Promote the Migration and Invasion of Colorectal Cancer Cell [Corrigendum] | Full Text | PDF (147.6 KB) | EPUB
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Original Research

Article
Ocular Metastasis in Elderly Lung Cancer Patients: Potential Risk Factors of CA-125, CA-153 and TPSA
Qian-Min Ge, Yu-Ting Zou, Wen-Qing Shi, Yu-Qing Zhang, Biao Li, You-Lan Min, Qing Yuan & Yi Shao
Pages: 1801-1808
Published online: 10 Mar 2020
AbstractforOcular Metastasis in Elderly Lung Cancer Patients: Potential Risk Factors of CA-125, CA-153 and TPSA | Full Text | References | PDF (2.9 MB) | EPUB
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Article
Association of the Preoperative Inflammation-Based Scores with TNM Stage and Recurrence in Patients with Papillary Thyroid Carcinoma: A Retrospective, Multicenter Analysis
Wenjie Chen, Tao Wei, Zhihui Li, Rixiang Gong, Jianyong Lei, Jingqiang Zhu & Tao Huang
Pages: 1809-1818
Published online: 11 Mar 2020
AbstractforAssociation of the Preoperative Inflammation-Based Scores with TNM Stage and Recurrence in Patients with Papillary Thyroid Carcinoma: A Retrospective, Multicenter Analysis | Full Text | References | PDF (3.1 MB) | EPUB
  • 120 Views
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Article
The Vascular Index of Superb Microvascular Imaging Can Improve the Diagnostic Accuracy for Breast Imaging Reporting and Data System Category 4 Breast Lesions
Si-Man Cai, Hong-Yan Wang, Xiao-Yan Zhang, Li Zhang, Qing-Li Zhu, Jian-Chu Li, Qiang Sun & Yu-Xin Jiang
Pages: 1819-1826
Published online: 11 Mar 2020
AbstractforThe Vascular Index of Superb Microvascular Imaging Can Improve the Diagnostic Accuracy for Breast Imaging Reporting and Data System Category 4 Breast Lesions | Full Text | References | PDF (2.1 MB) | EPUB
  • 118 Views
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Article
LncRNA FEZF1-AS1 Sponges miR-34a to Upregulate Notch-1 in Glioblastoma
Lun Luo, Yuan Zhang, Haiyong He, Chuan Chen, Baoyu Zhang & Meiqin Cai
Pages: 1827-1833
Published online: 11 Mar 2020
AbstractforLncRNA FEZF1-AS1 Sponges miR-34a to Upregulate Notch-1 in Glioblastoma | Full Text | References | PDF (5.1 MB) | EPUB
  • 65 Views
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Article
LncRNA NR2F2-AS1 Silencing Induces Cell Cycle Arrest in G0/G1 Phase via Downregulating Cyclin D1 in Colorectal Cancer
Jianfeng Liu, Jun Qian, Qi Mo, Liming Tang & Qiang Xu
Pages: 1835-1843
Published online: 11 Mar 2020
AbstractforLncRNA NR2F2-AS1 Silencing Induces Cell Cycle Arrest in G0/G1 Phase via Downregulating Cyclin D1 in Colorectal Cancer | Full Text | References | PDF (3 MB) | EPUB
  • 85 Views
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Article
Identification of Cholangiocarcinoma Associated with Hepatolithiasis via the Combination of miRNA and Ultrasound
Wei Jiang, Xiaofei Deng, Ting Zhu, Yuya Wei, Zhen Lei, Meimei Guo & Jiong Yang
Pages: 1845-1853
Published online: 12 Mar 2020
AbstractforIdentification of Cholangiocarcinoma Associated with Hepatolithiasis via the Combination of miRNA and Ultrasound | Full Text | References | PDF (3 MB) | EPUB
  • 65 Views
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Article
Preoperative Sonographic and Clinicopathological Predictors for Solitary Lateral Neck Node Metastasis in Papillary Thyroid Carcinoma: A Retrospective Study
Qiong Yang, Pei Chen, Hui-Yu Hu, Hai-long Tan, Gui-you Li, Mian Liu, Deng-jie Ou-yang, Rooh-afza Khushbu, Deepak Pun, Zhi-peng Zhang, Peng Huang & Shi Chang
Pages: 1855-1862
Published online: 12 Mar 2020
AbstractforPreoperative Sonographic and Clinicopathological Predictors for Solitary Lateral Neck Node Metastasis in Papillary Thyroid Carcinoma: A Retrospective Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 63 Views
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Article
Melatonin Regulates Cisplatin Resistance and Glucose Metabolism Through Hippo Signaling in Hepatocellular Carcinoma Cells
Lina Mi & Hongyu Kuang
Pages: 1863-1874
Published online: 12 Mar 2020
AbstractforMelatonin Regulates Cisplatin Resistance and Glucose Metabolism Through Hippo Signaling in Hepatocellular Carcinoma Cells | Full Text | References | PDF (7.9 MB) | EPUB
  • 100 Views
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Corrigendum

Correction
Intraoperative Prediction of Non-Sentinel Lymph Node Metastasis Based on the Molecular Assay in Breast Cancer Patients [Corrigendum]
Page: 1875
Published online: 12 Mar 2020
CitationforIntraoperative Prediction of Non-Sentinel Lymph Node Metastasis Based on the Molecular Assay in Breast Cancer Patients [Corrigendum] | Full Text | PDF (147.7 KB) | EPUB
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Original Research

Article
hsa_circRNA_012515 Is Highly Expressed in NSCLC Patients and Affects Its Prognosis
Yunfeng Fu, Liang Huang, Hao Tang & Rong Huang
Pages: 1877-1886
Published online: 12 Mar 2020
Abstractforhsa_circRNA_012515 Is Highly Expressed in NSCLC Patients and Affects Its Prognosis | Full Text | References | PDF (6.9 MB) | EPUB
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Methodology

Prediction and Monitoring Method for Breast Cancer: A Case Study for Data from the University Hospital Centre of Coimbra
Jin Yue, Na Zhao & Liu Liu
Pages: 1887-1893
Published online: 13 Mar 2020
AbstractforPrediction and Monitoring Method for Breast Cancer: A Case Study for Data from the University Hospital Centre of Coimbra | Full Text | References | PDF (1.6 MB) | EPUB
  • 218 Views
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Original Research

Article
Prognostic Significance of Metastatic Lymph Nodes Ratio (MLNR) Combined with Protein-Tyrosine Phosphatase H1 (PTPH1) Expression in Operable Breast Invasive Ductal Carcinoma
Shao Ma, Yanrong Lv & Rong Ma
Pages: 1895-1901
Published online: 13 Mar 2020
AbstractforPrognostic Significance of Metastatic Lymph Nodes Ratio (MLNR) Combined with Protein-Tyrosine Phosphatase H1 (PTPH1) Expression in Operable Breast Invasive Ductal Carcinoma | Full Text | References | PDF (2.6 MB) | EPUB
  • 60 Views
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Article
High-Grade B-Cell Lymphomas, Not Otherwise Specified: A Study of 41 Cases
Jiayin Li, Xiaoyin Liu, Zhihua Yao & Mingzhi Zhang
Pages: 1903-1912
Published online: 13 Mar 2020
AbstractforHigh-Grade B-Cell Lymphomas, Not Otherwise Specified: A Study of 41 Cases | Full Text | References | PDF (3.7 MB) | EPUB
  • 115 Views
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Article
Anticancer Effects of Antihypertensive L-Type Calcium Channel Blockers on Chemoresistant Lung Cancer Cells via Autophagy and Apoptosis
Bing-Sang Wong, Ling-Yen Chiu, Dom-Gene Tu, Gwo-Tarng Sheu & Ting-Tat Chan
Pages: 1913-1927
Published online: 13 Mar 2020
AbstractforAnticancer Effects of Antihypertensive L-Type Calcium Channel Blockers on Chemoresistant Lung Cancer Cells via Autophagy and Apoptosis | Full Text | References | PDF (5.7 MB) | EPUB
  • 147 Views
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Article
LncRNA MALAT1 Regulates the Cell Proliferation and Cisplatin Resistance in Gastric Cancer via PI3K/AKT Pathway
Qingqiang Dai, Tianqi Zhang & Chen Li
Pages: 1929-1939
Published online: 13 Mar 2020
AbstractforLncRNA MALAT1 Regulates the Cell Proliferation and Cisplatin Resistance in Gastric Cancer via PI3K/AKT Pathway | Full Text | References | PDF (9.8 MB) | EPUB
  • 135 Views
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Article
Increased Expression of TAP Is Predictive of Poor Prognosis in Patients with Non-Small Cell Lung Cancer
Yuanjun Cheng, Yongbing Chen, Guohui Zang, Bin Chen, Jie Yao, Wenguang Zhang, Haibing Wang, Liu Yu, Pinghai He, Youming Zhang & Hanqing Wu
Pages: 1941-1946
Published online: 13 Mar 2020
AbstractforIncreased Expression of TAP Is Predictive of Poor Prognosis in Patients with Non-Small Cell Lung Cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 76 Views
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Article
Concordance of Treatment Recommendations for Metastatic Non-Small-Cell Lung Cancer Between Watson for Oncology System and Medical Team
Hai-Sheng You, Chun-Xia Gao, Hai-Bin Wang, Sai-Sai Luo, Si-Ying Chen, Ya-Lin Dong, Jun Lyu & Tao Tian
Pages: 1947-1958
Published online: 16 Mar 2020
AbstractforConcordance of Treatment Recommendations for Metastatic Non-Small-Cell Lung Cancer Between Watson for Oncology System and Medical Team | Full Text | References | PDF (1.4 MB) | EPUB
  • 141 Views
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Article
Low Prognostic Nutritional Index Predicts Poor Clinical Outcomes in Patients with Stage IIIB Non-small-cell Lung Carcinoma Undergoing Chemoradiotherapy
Yurday Ozdemir, Erkan Topkan, Huseyin Mertsoylu & Ugur Selek
Pages: 1959-1967
Published online: 16 Mar 2020
AbstractforLow Prognostic Nutritional Index Predicts Poor Clinical Outcomes in Patients with Stage IIIB Non-small-cell Lung Carcinoma Undergoing Chemoradiotherapy | Full Text | References | PDF (2.1 MB) | EPUB
  • 78 Views
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Article
A Preliminary Study on the Establishment of the PDTX Model
Yong Liu, Yan-Ping Zhu, Ming-Zhi Cai, Bin Ke, Bin Li, Ning Liu, Qiang Xue, Hong-Jie Zhan, Jing-Yu Deng, Li Zhang, Yan-Peng Hao, Zhi-Qiang Wang, Li Wang & Han Liang
Pages: 1969-1979
Published online: 17 Mar 2020
AbstractforA Preliminary Study on the Establishment of the PDTX Model | Full Text | References | PDF (5.8 MB) | EPUB
  • 71 Views
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Article
A New Immunological Prognostic Model Based on Immunohistochemistry for Extranodal Natural Killer/T-Cell Lymphoma Patients After Non-Anthracycline-Based Chemotherapy
Sio Teng Lam, He Huang, Xiaojie Fang, Zhao Wang, Huangming Hong, Quanguang Ren, Ying Tian, Suxia Lin & Tongyu Lin
Pages: 1981-1990
Published online: 17 Mar 2020
AbstractforA New Immunological Prognostic Model Based on Immunohistochemistry for Extranodal Natural Killer/T-Cell Lymphoma Patients After Non-Anthracycline-Based Chemotherapy | Full Text | References | PDF (2 MB) | EPUB
  • 68 Views
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Article
Screening and Identification of Potential Biomarkers for Hepatocellular Carcinoma: An Analysis of TCGA Database and Clinical Validation
Xianli Wei, Junzi Ke, Haonan Huang, Shikun Zhou, Ao Guo, Kun Wang, Yujuan Zhan, Cong Mai, Weizhen Ao, Fuda Xie, Rongping Luo, Jianyong Xiao, Hang Wei & Bonan Chen
Pages: 1991-2000
Published online: 17 Mar 2020
AbstractforScreening and Identification of Potential Biomarkers for Hepatocellular Carcinoma: An Analysis of TCGA Database and Clinical Validation | Full Text | References | PDF (3.9 MB) | EPUB
  • 90 Views
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Article
LncRNA-ATB Promotes Cisplatin Resistance in Lung Adenocarcinoma Cells by Targeting the miR-200a/β-Catenin Pathway
Weiwei Tang, Xiuyi Yu, Ru Zeng & Lilin Chen
Pages: 2001-2014
Published online: 18 Mar 2020
AbstractforLncRNA-ATB Promotes Cisplatin Resistance in Lung Adenocarcinoma Cells by Targeting the miR-200a/β-Catenin Pathway | Full Text | References | PDF (11.5 MB) | EPUB
  • 79 Views
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Article
Prognostic Value of Pretreatment Albumin-to-Alkaline Phosphatase Ratio in Extensive-Disease Small-Cell Lung Cancer: A Retrospective Cohort Study
Shaozhang Zhou, Huiling Wang, Wei Jiang, Qitao Yu & Aiping Zeng
Pages: 2015-2024
Published online: 18 Mar 2020
AbstractforPrognostic Value of Pretreatment Albumin-to-Alkaline Phosphatase Ratio in Extensive-Disease Small-Cell Lung Cancer: A Retrospective Cohort Study | Full Text | References | PDF (1.4 MB) | EPUB
  • 104 Views
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Article
Establishment of Simple Nomograms for Predicting Axillary Lymph Node Involvement in Early Breast Cancer
Qingqing Zong, Jing Deng, Wanli Ge, Jie Chen & Di Xu
Pages: 2025-2035
Published online: 18 Mar 2020
AbstractforEstablishment of Simple Nomograms for Predicting Axillary Lymph Node Involvement in Early Breast Cancer | Full Text | References | PDF (4.7 MB) | EPUB
  • 77 Views
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Article
Qualitative Evaluation of Virtual Touch Imaging Quantification: A Simple and Useful Method in the Diagnosis of Breast Lesions
Ying Zhu, Xiao-hong Jia, Wei Zhou, Wei-wei Zhan & Jian-qiao Zhou
Pages: 2037-2045
Published online: 18 Mar 2020
AbstractforQualitative Evaluation of Virtual Touch Imaging Quantification: A Simple and Useful Method in the Diagnosis of Breast Lesions | Full Text | References | PDF (1 MB) | EPUB
  • 60 Views
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Article
A Modified ypTNM Staging System–Development and External Validation of a Nomogram Predicting the Overall Survival of Gastric Cancer Patients Received Neoadjuvant Chemotherapy
Ziyu Li, Qiyan Xiao, Yinkui Wang, Wei Wang, Shuangxi Li, Fei Shan, Zhiwei Zhou & Jiafu Ji
Pages: 2047-2055
Published online: 19 Mar 2020
AbstractforA Modified ypTNM Staging System–Development and External Validation of a Nomogram Predicting the Overall Survival of Gastric Cancer Patients Received Neoadjuvant Chemotherapy | Full Text | References | PDF (3 MB) | EPUB
  • 67 Views
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Article
Oxymatrine Inhibits Proliferation and Migration of Vulvar Squamous Cell Carcinoma Cells via Attenuation of the RAS/RAF/MEK/ERK Pathway
Yanshi Wang, Shaojie Yang, Shanshan Zhang & Xin Wu
Pages: 2057-2067
Published online: 19 Mar 2020
AbstractforOxymatrine Inhibits Proliferation and Migration of Vulvar Squamous Cell Carcinoma Cells via Attenuation of the RAS/RAF/MEK/ERK Pathway | Full Text | References | PDF (5.4 MB) | EPUB
  • 80 Views
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Article
Detection of PD-L1 Expression and Its Clinical Significance in Circulating Tumor Cells from Patients with Non-Small-Cell Lung Cancer
Yuxin Cheng, Ting Wang, Xin Lv, Rutian Li, Ling Yuan, Jie Shen, Yan Li, Tingting Yan, Baorui Liu & Lifeng Wang
Pages: 2069-2078
Published online: 19 Mar 2020
AbstractforDetection of PD-L1 Expression and Its Clinical Significance in Circulating Tumor Cells from Patients with Non-Small-Cell Lung Cancer | Full Text | References | PDF (1.2 MB) | EPUB
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Review

Review Article
Acalabrutinib and Its Therapeutic Potential in the Treatment of Chronic Lymphocytic Leukemia: A Short Review on Emerging Data
Krista Isaac & Anthony R Mato
Pages: 2079-2085
Published online: 19 Mar 2020
AbstractforAcalabrutinib and Its Therapeutic Potential in the Treatment of Chronic Lymphocytic Leukemia: A Short Review on Emerging Data | Full Text | References | PDF (235.7 KB) | EPUB
  • 204 Views
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Original Research

Article
KRT17 Functions as a Tumor Promoter and Regulates Proliferation, Migration and Invasion in Pancreatic Cancer via mTOR/S6k1 Pathway
Ding Li, Xiao-Feng Ni, Hengjie Tang, Jiecheng Zhang, Chenlei Zheng, Jianhu Lin, Cheng Wang, Linxiao Sun & Bicheng Chen
Pages: 2087-2095
Published online: 19 Mar 2020
AbstractforKRT17 Functions as a Tumor Promoter and Regulates Proliferation, Migration and Invasion in Pancreatic Cancer via mTOR/S6k1 Pathway | Full Text | References | PDF (4.7 MB) | EPUB
  • 117 Views
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Article
Upregulation of DUSP14 Affects Proliferation, Invasion and Metastasis, Potentially via Epithelial–Mesenchymal Transition and Is Associated with Poor Prognosis in Pancreatic Cancer
Yajun Wei, Gang Wang, Cheng Wang, Yangming Zhou, Jingcheng Zhang & Kai Xu
Pages: 2097-2108
Published online: 20 Mar 2020
AbstractforUpregulation of DUSP14 Affects Proliferation, Invasion and Metastasis, Potentially via Epithelial–Mesenchymal Transition and Is Associated with Poor Prognosis in Pancreatic Cancer | Full Text | References | PDF (7.8 MB) | EPUB
  • 75 Views
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Article
hsa_circRNA_101237: A Novel Diagnostic and Prognostic Biomarker and Potential Therapeutic Target for Multiple Myeloma
Xiao Liu, Hao Tang, Jing Liu & Xiang Wang
Pages: 2109-2118
Published online: 20 Mar 2020
Abstractforhsa_circRNA_101237: A Novel Diagnostic and Prognostic Biomarker and Potential Therapeutic Target for Multiple Myeloma | Full Text | References | PDF (6 MB) | EPUB
  • 109 Views
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Article
LncRNA MORT Inhibits Cancer Cell Proliferation and Promotes Apoptosis in Mantle Cell Lymphoma by Upregulating miRNA-16
Xiaoqiong Tang, Yaoying Long, Liuyue Xu & Xinyu Yan
Pages: 2119-2125
Published online: 23 Mar 2020
AbstractforLncRNA MORT Inhibits Cancer Cell Proliferation and Promotes Apoptosis in Mantle Cell Lymphoma by Upregulating miRNA-16 | Full Text | References | PDF (6.3 MB) | EPUB
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Expert Opinion

Article Commentary
Chinese Expert Consensus on the Diagnosis and Treatment of Castration-Resistant Prostate Cancer (2019 Update)
Yao Zhu, Dingwei Ye & On behalf of the Expert Group
Pages: 2127-2140
Published online: 23 Mar 2020
AbstractforChinese Expert Consensus on the Diagnosis and Treatment of Castration-Resistant Prostate Cancer (2019 Update) | Full Text | References | PDF (323.7 KB) | EPUB
  • 144 Views
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Original Research

Article
RETRACTED ARTICLE: LncRNA EMX2OS Induces Proliferation, Invasion and Sphere Formation of Ovarian Cancer Cells via Regulating the miR-654-3p/AKT3/PD-L1 Axis
Meng Duan, Meixia Fang, Changhe Wang, Hongyan Wang & Meng Li
Pages: 2141-2154
Published online: 24 Mar 2020
AbstractforRETRACTED ARTICLE: LncRNA EMX2OS Induces Proliferation, Invasion and Sphere Formation of Ovarian Cancer Cells via Regulating the miR-654-3p/AKT3/PD-L1 Axis | PDF (10 MB)
  • 119 Views
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Review

Review Article
Significance of CXCL12/CXCR4 Ligand/Receptor Axis in Various Aspects of Acute Myeloid Leukemia
Zinat Yazdani, Zahra Mousavi, Alireza Moradabadi & Gholamhossein Hassanshahi
Pages: 2155-2165
Published online: 24 Mar 2020
AbstractforSignificance of CXCL12/CXCR4 Ligand/Receptor Axis in Various Aspects of Acute Myeloid Leukemia | Full Text | References | PDF (397.1 KB) | EPUB
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Original Research

Article
Risk Prediction and Prognosis of Invasive Fungal Disease in Hematological Malignancies Patients Complicated with Bloodstream Infections
Han Xiao, Yishu Tang, Qian Cheng, Jing Liu & Xin Li
Pages: 2167-2175
Published online: 24 Mar 2020
AbstractforRisk Prediction and Prognosis of Invasive Fungal Disease in Hematological Malignancies Patients Complicated with Bloodstream Infections | Full Text | References | PDF (277.6 KB) | EPUB
  • 98 Views
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Article
Association Between Multiple Lines of Active Therapy and Prognosis in Esophageal Squamous Cell Carcinoma
Ying Yang, Jun Jia, Zhiwei Sun, Chuanling Liu, Yanjie Xiao, Jing Yu, Feng Du & Xiaodong Zhang
Pages: 2177-2184
Published online: 24 Mar 2020
AbstractforAssociation Between Multiple Lines of Active Therapy and Prognosis in Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (839 KB) | EPUB
  • 59 Views
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Article
Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion
Xu Jing, Yingjie Chen, Ye Chen, Guangyan Shi, Shuanghao Lv, Nana Cheng, Chaolin Feng, Zhen Xin, Liping Zhang & Jing Wu
Pages: 2185-2194
Published online: 24 Mar 2020
AbstractforDown-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion | Full Text | References | PDF (3.7 MB) | EPUB
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Article
RETRACTED ARTICLE: Long Non-Coding RNA CASC19 Sponges microRNA-532 and Promotes Oncogenicity of Clear Cell Renal Cell Carcinoma by Increasing ETS1 Expression
Yu Luo, Feng Liu, Chunhui Yan, Wei Qu, Liang Zhu, Zheng Guo, Fan Zhou & Wei Zhang
Pages: 2195-2207
Published online: 24 Mar 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA CASC19 Sponges microRNA-532 and Promotes Oncogenicity of Clear Cell Renal Cell Carcinoma by Increasing ETS1 Expression | PDF (8 MB)
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Article
HIF-1α, TWIST-1 and ITGB-1, associated with Tumor Stiffness, as Novel Predictive Markers for the Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer
Jing Zhang, Shuo Zhang, Song Gao, Yan Ma, Xueying Tan, Ye Kang & Weidong Ren
Pages: 2209-2222
Published online: 24 Mar 2020
AbstractforHIF-1α, TWIST-1 and ITGB-1, associated with Tumor Stiffness, as Novel Predictive Markers for the Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer | Full Text | References | PDF (6.4 MB) | EPUB
  • 114 Views
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Article
Prognostic Significance of Log(CA125)/PCI for the Resectability of Epithelial Ovarian Cancer: A Retrospective Study
Can He, Niresh Thapa, Yang Wang, Ziye Song, Jing Yang, Mengfei Xu, Na Zuo & Hongbing Cai
Pages: 2223-2230
Published online: 25 Mar 2020
AbstractforPrognostic Significance of Log(CA125)/PCI for the Resectability of Epithelial Ovarian Cancer: A Retrospective Study | Full Text | References | PDF (3.5 MB) | EPUB
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Review

Review Article
Genetic Characterization and Risk Stratification of Acute Myeloid Leukemia
Fatemeh Pourrajab, Mohamad Reza Zare-Khormizi, Azam Sadat Hashemi & Seyedhossein Hekmatimoghaddam
Pages: 2231-2253
Published online: 25 Mar 2020
AbstractforGenetic Characterization and Risk Stratification of Acute Myeloid Leukemia | Full Text | References | PDF (2.4 MB) | EPUB
  • 496 Views
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Methodology

An Innovative Approach to Clinical Practice Guideline Adaptation in the Nursing Profession in a Developing Country
Shahin Salarvand, Simin Hemati, Payman Adibi, Fariba Taleghani & Mohammad Saleki
Pages: 2255-2264
Published online: 25 Mar 2020
AbstractforAn Innovative Approach to Clinical Practice Guideline Adaptation in the Nursing Profession in a Developing Country | Full Text | References | PDF (511.8 KB) | EPUB
  • 240 Views
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Original Research

Article
RETRACTED ARTICLE: Long Noncoding RNA FGD5-AS1 Acts as a Competing Endogenous RNA on microRNA-383 to Enhance the Malignant Characteristics of Esophageal Squamous Cell Carcinoma by Increasing SP1 Expression
Jia Gao, Ziteng Zhang, Hong Su, Ling Zong & Yan Li
Pages: 2265-2278
Published online: 26 Mar 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA FGD5-AS1 Acts as a Competing Endogenous RNA on microRNA-383 to Enhance the Malignant Characteristics of Esophageal Squamous Cell Carcinoma by Increasing SP1 Expression | PDF (9.9 MB)
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Article
Impact of Nutritional Indices on the Survival Outcomes of Patients with Colorectal Cancer
Zhengyu Hu, Yan Li, Weipu Mao, Bo Chen, Lin Yang & Xiangling Meng
Pages: 2279-2289
Published online: 26 Mar 2020
AbstractforImpact of Nutritional Indices on the Survival Outcomes of Patients with Colorectal Cancer | Full Text | References | PDF (5 MB) | EPUB
  • 96 Views
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Article
MiR-802 Suppresses Colorectal Cancer Cell Viability, Migration and Invasion by Targeting RAN
Hailong Feng, Lingling Liu, Laijing Xu, Haili Wang, Qiuju Hua & Peng He
Pages: 2291-2300
Published online: 26 Mar 2020
AbstractforMiR-802 Suppresses Colorectal Cancer Cell Viability, Migration and Invasion by Targeting RAN | Full Text | References | PDF (6.1 MB) | EPUB
  • 93 Views
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Article
Acetyl-11-keto-β-boswellic Acid Inhibits Precancerous Breast Lesion MCF-10AT Cells via Regulation of LINC00707/miR-206 that Reduces Estrogen Receptor-α
Xuefeng Jiang, Yusheng Liu, Guijuan Zhang, Shujun Lin, Naijun Yuan, Jieyan Wu, Xianxin Yan, Yi Ma & Min Ma
Pages: 2301-2314
Published online: 27 Mar 2020
AbstractforAcetyl-11-keto-β-boswellic Acid Inhibits Precancerous Breast Lesion MCF-10AT Cells via Regulation of LINC00707/miR-206 that Reduces Estrogen Receptor-α | Full Text | References | PDF (10.9 MB) | EPUB
  • 87 Views
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Article
Short-Term Clinical and Oncological Outcome of Prolonging Operation Interval After Neoadjuvant Chemoradiotherapy for Locally Advanced Middle and Low Rectal Cancer
Jianguo Yang, Qingwei Chen, Jindou Li, Zhiyang Song & Yong Cheng
Pages: 2315-2325
Published online: 27 Mar 2020
AbstractforShort-Term Clinical and Oncological Outcome of Prolonging Operation Interval After Neoadjuvant Chemoradiotherapy for Locally Advanced Middle and Low Rectal Cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 67 Views
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Article
Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis
Weiping Yang, Piguo Gong, Yifeng Yang, Chunyan Yang, Baohui Yang & Lijun Ren
Pages: 2327-2337
Published online: 27 Mar 2020
AbstractforCirc-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis | Full Text | References | PDF (4.8 MB) | EPUB
  • 102 Views
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Article
LINC00963 Confers Oncogenic Properties in Glioma by Regulating the miR-506/BCAT1 Axis
Feng Ye, Ronghua Xu, Yuanhong Ge, Yi Zheng, Xiaowei Liu, Pingfu Deng & Xuejun Xu
Pages: 2339-2351
Published online: 27 Mar 2020
AbstractforLINC00963 Confers Oncogenic Properties in Glioma by Regulating the miR-506/BCAT1 Axis | Full Text | References | PDF (9.8 MB) | EPUB
  • 68 Views
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Article
Expression of Carboxypeptidase X M14 Family Member 2 Accelerates the Progression of Hepatocellular Carcinoma via Regulation of the gp130/JAK2/Stat1 Pathway
Yanshuo Ye, Yuan An, Min Wang, Hongyu Liu, Lianyue Guan, Zhanpeng Wang & Wei Li
Pages: 2353-2364
Published online: 31 Mar 2020
AbstractforExpression of Carboxypeptidase X M14 Family Member 2 Accelerates the Progression of Hepatocellular Carcinoma via Regulation of the gp130/JAK2/Stat1 Pathway | Full Text | References | PDF (2.6 MB) | EPUB
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Corrigendum

Correction
Oral Maintenance Chemotherapy Using S-1/Capecitabine in Metastatic Nasopharyngeal Carcinoma Patients After Systemic Chemotherapy: A Single-Institution Experience [Corrigendum]
Pages: 2365-2366
Published online: 31 Mar 2020
CitationforOral Maintenance Chemotherapy Using S-1/Capecitabine in Metastatic Nasopharyngeal Carcinoma Patients After Systemic Chemotherapy: A Single-Institution Experience [Corrigendum] | Full Text | PDF (1.1 MB) | EPUB
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Retraction

Retraction
Long Noncoding RNA ZFPM2-AS1 Enhances the Malignancy of Cervical Cancer by Functioning as a Molecular Sponge of microRNA-511-3p and Consequently Increasing FGFR2 Expression [Retraction]
Page: 2367
Published online: 31 Mar 2020
CitationforLong Noncoding RNA ZFPM2-AS1 Enhances the Malignancy of Cervical Cancer by Functioning as a Molecular Sponge of microRNA-511-3p and Consequently Increasing FGFR2 Expression [Retraction] | Full Text | PDF (152.1 KB) | EPUB
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Original Research

Article
Evaluation of PCR-Reverse Dot Blot Human Papillomavirus Genotyping Test in Predicting Residual/Recurrent CIN 2+ in Posttreatment Patients in China
Qiaoyu Zhang, Binhua Dong, Lihua Chen, Tingting Lin, Yao Tong, Wenyu Lin, Haifeng Lin, Yuqin Gao, Fen Lin & Pengming Sun
Pages: 2369-2379
Published online: 01 Apr 2020
AbstractforEvaluation of PCR-Reverse Dot Blot Human Papillomavirus Genotyping Test in Predicting Residual/Recurrent CIN 2+ in Posttreatment Patients in China | Full Text | References | PDF (880.9 KB) | EPUB
  • 87 Views
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Article
B3GNT3, a Direct Target of miR-149-5p, Promotes Lung Cancer Development and Indicates Poor Prognosis of Lung Cancer
Yu Sun, Tao Liu, Lei Xian, Wenzhou Liu, Jun Liu & Huafu Zhou
Pages: 2381-2391
Published online: 31 Mar 2020
AbstractforB3GNT3, a Direct Target of miR-149-5p, Promotes Lung Cancer Development and Indicates Poor Prognosis of Lung Cancer | Full Text | References | PDF (9.3 MB) | EPUB
  • 87 Views
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Review

Review Article
MicroRNAs Targeting MYC Expression: Trace of Hope for Pancreatic Cancer Therapy. A Systematic Review
Roshanak Shams, Hamid Asadzadeh Aghdaei, Ali Behmanesh, Amir Sadeghi, Mohammadareza Zali, Sina Salari & José M Padrón
Pages: 2393-2404
Published online: 01 Apr 2020
AbstractforMicroRNAs Targeting MYC Expression: Trace of Hope for Pancreatic Cancer Therapy. A Systematic Review | Full Text | References | PDF (3.6 MB) | EPUB
  • 148 Views
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Original Research

Article
Astragalus Polysaccharide Promotes Adriamycin-Induced Apoptosis in Gastric Cancer Cells
Jie Song, Youming Chen, Donghong He, Wenhui Tan, Fang Lv, Biao Liang, Tingting Xia & Jing Li
Pages: 2405-2414
Published online: 01 Apr 2020
AbstractforAstragalus Polysaccharide Promotes Adriamycin-Induced Apoptosis in Gastric Cancer Cells | Full Text | References | PDF (905.7 KB) | EPUB
  • 99 Views
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Article
Prognostic Value of Inflammation Biomarkers for Survival of Patients with Neuroblastoma
Chen Zheng, Shuaibin Liu, Jiexiong Feng & Xiang Zhao
Pages: 2415-2425
Published online: 01 Apr 2020
AbstractforPrognostic Value of Inflammation Biomarkers for Survival of Patients with Neuroblastoma | Full Text | References | PDF (3.4 MB) | EPUB
  • 102 Views
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Article
Risk of Recurrence and Metastasis for Patients with T1N0M0 Esophageal Carcinoma Who Achieve Completed Resection via Endoscopic Submucosal Resection: Evidence for the Appropriateness of the Watch and Wait Follow-Up Strategy
Li-Hua Zhu, Jun Yao, Ting Wu, Yan Wang, Chen-Wei Wang, Chun-Quan Xue, Li-Guang Wu, Xing-Wen Fan & Chao-Yang Wu
Pages: 2427-2435
Published online: 02 Apr 2020
AbstractforRisk of Recurrence and Metastasis for Patients with T1N0M0 Esophageal Carcinoma Who Achieve Completed Resection via Endoscopic Submucosal Resection: Evidence for the Appropriateness of the Watch and Wait Follow-Up Strategy | Full Text | References | PDF (2.7 MB) | EPUB
  • 76 Views
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Article
Different Proteins Regulated Apoptosis, Proliferation and Metastasis of Lung Adenocarcinoma After Radiotherapy at Different Time
P L Dai, X S Du, Y Hou, L Li, Y X Xia, L Wang, H X Chen, L Chang & W H Li
Pages: 2437-2447
Published online: 02 Apr 2020
AbstractforDifferent Proteins Regulated Apoptosis, Proliferation and Metastasis of Lung Adenocarcinoma After Radiotherapy at Different Time | Full Text | References | PDF (4.6 MB) | EPUB
  • 74 Views
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Article
99mTc-Methylene Diphosphonate Uptake in Soft Tissue Tumors on Bone Scintigraphy Differs Between Pediatric and Adult Patients and Is Correlated with Tumor Differentiation
Simin Liu, Jianhao Xie, Fei Yu, Haidong Cai, Fengyu Wu, Hui Zheng, Chao Ma, Zhongwei Lv & Hui Wang
Pages: 2449-2457
Published online: 03 Apr 2020
Abstractfor99mTc-Methylene Diphosphonate Uptake in Soft Tissue Tumors on Bone Scintigraphy Differs Between Pediatric and Adult Patients and Is Correlated with Tumor Differentiation | Full Text | References | PDF (4.1 MB) | EPUB
  • 127 Views
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Article
Ultrasound-Mediated Co-Delivery of miR-34a and sPD-1 Complexed with Microbubbles for Synergistic Cancer Therapy
Yu-e Qin, Wen-fan Tang, Yun Xu, Fu-rong Wan & Ai-hua Chen
Pages: 2459-2469
Published online: 05 Apr 2020
AbstractforUltrasound-Mediated Co-Delivery of miR-34a and sPD-1 Complexed with Microbubbles for Synergistic Cancer Therapy | Full Text | References | PDF (6.9 MB) | EPUB
  • 85 Views
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Article
Circular RNA Circ-ZNF609 Promotes Lung Adenocarcinoma Proliferation by Modulating miR-1224-3p/ETV1 Signaling
Yangsong Zuo, Wenyi Shen, Chengshi Wang, Niu Niu & Juan Pu
Pages: 2471-2479
Published online: 07 Apr 2020
AbstractforCircular RNA Circ-ZNF609 Promotes Lung Adenocarcinoma Proliferation by Modulating miR-1224-3p/ETV1 Signaling | Full Text | References | PDF (1.5 MB) | EPUB
  • 108 Views
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Article
Trastuzumab with FLOT Regimen for the Perioperative Treatment of Resectable HER2 + Advanced Gastric Cancer: A Retrospective Study
Gangling Tong, Shuluan Li, Lin Lin, Lirui He, Li Wang, Guoqing Lv, Ruinian Zheng & Shubin Wang
Pages: 2481-2489
Published online: 08 Apr 2020
AbstractforTrastuzumab with FLOT Regimen for the Perioperative Treatment of Resectable HER2 + Advanced Gastric Cancer: A Retrospective Study | Full Text | References | PDF (411 KB) | EPUB
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Article
The Evaluation of Magee Equation 2 in Predicting Response and Outcome in Hormone Receptor-Positive and HER2-Negative Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
Napat Saigosoom, Doonyapat Sa-nguanraksa, Eng O-charoenrat, Thanawat Thumrongtaradol & Pornchai O-charoenrat
Pages: 2491-2499
Published online: 08 Apr 2020
AbstractforThe Evaluation of Magee Equation 2 in Predicting Response and Outcome in Hormone Receptor-Positive and HER2-Negative Breast Cancer Patients Receiving Neoadjuvant Chemotherapy | Full Text | References | PDF (1.6 MB) | EPUB
  • 94 Views
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Expression of Concern

Expression of Concern
Ras-ERK1/2 Signaling Promotes the Development of Osteosarcoma by Regulating H2BK12ac Through CBP [Expression of Concern]
Page: 2501
Published online: 08 Apr 2020
CitationforRas-ERK1/2 Signaling Promotes the Development of Osteosarcoma by Regulating H2BK12ac Through CBP [Expression of Concern] | Full Text | PDF (149.5 KB) | EPUB
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Original Research

Article
Intercalary Reconstruction of the “Ultra-Critical Sized Bone Defect” by 3D-Printed Porous Prosthesis After Resection of Tibial Malignant Tumor
Dingyun Zhao, Fan Tang, Li Min, Minxun Lu, Jie Wang, Yuqi Zhang, Kun Zhao, Yong Zhou, Yi Luo & Chongqi Tu
Pages: 2503-2512
Published online: 08 Apr 2020
AbstractforIntercalary Reconstruction of the “Ultra-Critical Sized Bone Defect” by 3D-Printed Porous Prosthesis After Resection of Tibial Malignant Tumor | Full Text | References | PDF (2.8 MB) | EPUB
  • 160 Views
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Article
Comparison of Radiation-Induced Secondary Malignancy Risk Between Sequential and Simultaneous Integrated Boost for the Treatment of Nasopharyngeal Carcinoma: Intensity-Modulated Radiotherapy versus Volumetric-Modulated Arc Therapy
Emel Haciislamoglu, Yunus Cinar, Mehmet Eren, Emine Canyilmaz, Fatih Gurcan, Lasif Serdar & Adnan Yoney
Pages: 2513-2521
Published online: 08 Apr 2020
AbstractforComparison of Radiation-Induced Secondary Malignancy Risk Between Sequential and Simultaneous Integrated Boost for the Treatment of Nasopharyngeal Carcinoma: Intensity-Modulated Radiotherapy versus Volumetric-Modulated Arc Therapy | Full Text | References | PDF (3.3 MB) | EPUB
  • 97 Views
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Article
Clinical Analysis of Risk Factors for Cervical Lymph Node Metastasis in Papillary Thyroid Microcarcinoma: A Retrospective Study of 3686 Patients
Jianlu Song, Ting Yan, Wangwang Qiu, Youben Fan & Zhili Yang
Pages: 2523-2530
Published online: 09 Apr 2020
AbstractforClinical Analysis of Risk Factors for Cervical Lymph Node Metastasis in Papillary Thyroid Microcarcinoma: A Retrospective Study of 3686 Patients | Full Text | References | PDF (292.5 KB) | EPUB
  • 92 Views
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Article
Serum Circular FoxO3a Serves as a Novel Prognostic Biomarker in Squamous Cervical Cancer
Xiaoyan Tang, Songping Liu, Yan Ding, Chenyan Guo, Jingjing Guo, Keqin Hua & Junjun Qiu
Pages: 2531-2540
Published online: 09 Apr 2020
AbstractforSerum Circular FoxO3a Serves as a Novel Prognostic Biomarker in Squamous Cervical Cancer | Full Text | References | PDF (4.6 MB) | EPUB
  • 88 Views
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Article
LncRNA RPSAP52 Upregulates TGF-β1 to Increase Cancer Cell Stemness and Predict Postoperative Survival in Glioblastoma
Shuwei Wang, Xinru Guo, Wenying Lv, Yanteng Li, Leiming Zhang, Chao Dong, Jianning Zhang & Gang Cheng
Pages: 2541-2547
Published online: 15 Apr 2020
AbstractforLncRNA RPSAP52 Upregulates TGF-β1 to Increase Cancer Cell Stemness and Predict Postoperative Survival in Glioblastoma | Full Text | References | PDF (3.2 MB) | EPUB
  • 75 Views
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Article
Diagnostic Value of Combining miRNAs, CEA Measurement and the FOBT in Colorectal Cancer Screening
Xiaodan Li, Rong Chen, Zhifa Li, Bing Luo, Wenyan Geng & Xiaobing Wu
Pages: 2549-2557
Published online: 15 Apr 2020
AbstractforDiagnostic Value of Combining miRNAs, CEA Measurement and the FOBT in Colorectal Cancer Screening | Full Text | References | PDF (2.6 MB) | EPUB
  • 91 Views
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Article
MiR-29b-3p Reverses Cisplatin Resistance by Targeting COL1A1 in Non-Small-Cell Lung Cancer A549/DDP Cells
Rui Jia & Changli Wang
Pages: 2559-2566
Published online: 16 Apr 2020
AbstractforMiR-29b-3p Reverses Cisplatin Resistance by Targeting COL1A1 in Non-Small-Cell Lung Cancer A549/DDP Cells | Full Text | References | PDF (2.6 MB) | EPUB
  • 119 Views
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Article
A Sensitive and Simplified Classifier of Cervical Lesions Based on a Methylation-Specific PCR Assay: A Chinese Cohort Study
Lei Zhang, Jing Yu, Wenxian Huang, Hongping Zhang, Jian Xu & Hongning Cai
Pages: 2567-2576
Published online: 15 Apr 2020
AbstractforA Sensitive and Simplified Classifier of Cervical Lesions Based on a Methylation-Specific PCR Assay: A Chinese Cohort Study | Full Text | References | PDF (807.3 KB) | EPUB
  • 129 Views
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Article
MicroRNA-584 Impairs Cellular Proliferation and Sensitizes Osteosarcoma Cells to Cisplatin and Taxanes by Targeting CCN2
Li Li, Xiang’an Kong, Mousheng Zang, Bin Hu, Xing Fang, Binjie Gui & Yong Hu
Pages: 2577-2587
Published online: 15 Apr 2020
AbstractforMicroRNA-584 Impairs Cellular Proliferation and Sensitizes Osteosarcoma Cells to Cisplatin and Taxanes by Targeting CCN2 | Full Text | References | PDF (9.9 MB) | EPUB
  • 65 Views
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Article
microRNA-519d Induces Autophagy and Apoptosis of Human Hepatocellular Carcinoma Cells Through Activation of the AMPK Signaling Pathway via Rab10
Yi-Jie Zhang, Qi Pan, Yang Yu & Xin-Ping Zhong
Pages: 2589-2602
Published online: 15 Apr 2020
AbstractformicroRNA-519d Induces Autophagy and Apoptosis of Human Hepatocellular Carcinoma Cells Through Activation of the AMPK Signaling Pathway via Rab10 | Full Text | References | PDF (4.3 MB) | EPUB
  • 99 Views
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Article
Prediction of Pathologic Complete Response by Ultrasonography and Magnetic Resonance Imaging After Neoadjuvant Chemotherapy in Patients with Breast Cancer
Kai Zhang, Jiawei Li, Qian Zhu & Cai Chang
Pages: 2603-2612
Published online: 16 Apr 2020
AbstractforPrediction of Pathologic Complete Response by Ultrasonography and Magnetic Resonance Imaging After Neoadjuvant Chemotherapy in Patients with Breast Cancer | Full Text | References | PDF (1,023.8 KB) | EPUB
  • 113 Views
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Article
Long-Term Survival in Patients Receiving Combination Therapy with Resection and Radiofrequency Ablation for Multi-Focal Hepatocellular Carcinoma Classified as Barcelona Clinic Liver Cancer Stage B: A Retrospective Controlled Study
Jun Yan, Zhongsong Man, Qian Lu & Kuansheng Ma
Pages: 2613-2621
Published online: 17 Apr 2020
AbstractforLong-Term Survival in Patients Receiving Combination Therapy with Resection and Radiofrequency Ablation for Multi-Focal Hepatocellular Carcinoma Classified as Barcelona Clinic Liver Cancer Stage B: A Retrospective Controlled Study | Full Text | References | PDF (3.4 MB) | EPUB
  • 72 Views
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Article
LncRNA PTCSC3 Alleviates the Postoperative Distant Recurrence of Gastric Cancer by Suppression of lncRNA HOXA11-AS
Jiapeng Xu, Yu Zhang, Qing You, Hongbing Fu, Xiaokai Zhao, Kai Lu, Ronglin Yan & Dejun Yang
Pages: 2623-2629
Published online: 17 Apr 2020
AbstractforLncRNA PTCSC3 Alleviates the Postoperative Distant Recurrence of Gastric Cancer by Suppression of lncRNA HOXA11-AS | Full Text | References | PDF (2.6 MB) | EPUB
  • 62 Views
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Article
Piceatannol Suppresses the Proliferation and Induced Apoptosis of Osteosarcoma Cells Through PI3K/AKT/mTOR Pathway
Bin Wang & Jingyu Li
Pages: 2631-2640
Published online: 20 Apr 2020
AbstractforPiceatannol Suppresses the Proliferation and Induced Apoptosis of Osteosarcoma Cells Through PI3K/AKT/mTOR Pathway | Full Text | References | PDF (7.4 MB) | EPUB
  • 116 Views
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Article
Targeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer
Jun Chang, Ling Hong, Yaozhong Liu, Yiwen Pan, Hao Yang, Wenrui Ye, Keli Xu, Zhijian Li & Shubing Zhang
Pages: 2641-2651
Published online: 20 Apr 2020
AbstractforTargeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer | Full Text | References | PDF (7.7 MB) | EPUB
  • 125 Views
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Article
Restoration of UPK1A-AS1 Expression Suppresses Cell Proliferation, Migration, and Invasion in Esophageal Squamous Cell Carcinoma Cells Partially by Sponging microRNA-1248
Fang Du, Tao Guo & Chenghua Cao
Pages: 2653-2662
Published online: 21 Apr 2020
AbstractforRestoration of UPK1A-AS1 Expression Suppresses Cell Proliferation, Migration, and Invasion in Esophageal Squamous Cell Carcinoma Cells Partially by Sponging microRNA-1248 | Full Text | References | PDF (5.8 MB) | EPUB
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Letter

Letter
Plasma Long Non-Coding RNA RP11-438N5.3 Level for Non-Small Cell Lung Cancer Diagnosis [Letter]
Chun-Qiu Yang & Guo-Ming Zhang
Pages: 2663-2664
Published online: 21 Apr 2020
CitationforPlasma Long Non-Coding RNA RP11-438N5.3 Level for Non-Small Cell Lung Cancer Diagnosis [Letter] | Full Text | References | PDF (229.6 KB) | EPUB
  • 57 Views
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Original Research

Article
A Preliminary Study of CT Texture Analysis for Characterizing Epithelial Tumors of the Parotid Gland
Dan Zhang, Xiaojiao Li, Liang Lv, Jiayi Yu, Chao Yang, Hua Xiong, Ruikun Liao, Bi Zhou, Xianlong Huang, Xiaoshuang Liu & Zhuoyue Tang
Pages: 2665-2674
Published online: 21 Apr 2020
AbstractforA Preliminary Study of CT Texture Analysis for Characterizing Epithelial Tumors of the Parotid Gland | Full Text | References | PDF (3.2 MB) | EPUB
  • 79 Views
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Article
Low Albumin to Fibrinogen Ratio Predicts Poor Overall Survival in Esophageal Small Cell Carcinoma Patients: A Retrospective Study
Yan Wang, Jialong Li, Shuai Chang, Kun Zhou & Guowei Che
Pages: 2675-2683
Published online: 21 Apr 2020
AbstractforLow Albumin to Fibrinogen Ratio Predicts Poor Overall Survival in Esophageal Small Cell Carcinoma Patients: A Retrospective Study | Full Text | References | PDF (1.9 MB) | EPUB
  • 64 Views
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Article
lncRNA DLX6-AS1 Promotes Proliferation of Laryngeal Cancer Cells by Targeting the miR-26a/TRPC3 Pathway
Yan Liu, Xinyi Liu, Xiaofeng Zhang, Jinhu Deng, Jian Zhang & Hao Xing
Pages: 2685-2695
Published online: 21 Apr 2020
AbstractforlncRNA DLX6-AS1 Promotes Proliferation of Laryngeal Cancer Cells by Targeting the miR-26a/TRPC3 Pathway | Full Text | References | PDF (8.4 MB) | EPUB
  • 87 Views
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Article
Biliverdin Reductase A (BLVRA) Promotes Colorectal Cancer Cell Progression by Activating the Wnt/β-Catenin Signaling Pathway
Haiyan Mao, Yuan Xu, Zhengrong Zhang, Guozhuang Sun, Zhu Wang, Dawei Qiao, Xudong Yin, Siping Liu & Ping Bo
Pages: 2697-2709
Published online: 23 Apr 2020
AbstractforBiliverdin Reductase A (BLVRA) Promotes Colorectal Cancer Cell Progression by Activating the Wnt/β-Catenin Signaling Pathway | Full Text | References | PDF (10.4 MB) | EPUB
  • 80 Views
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Article
Hounsfield Unit Values in ACR TI-RADS 4-5 Thyroid Nodules with Coarse Calcifications: An Important Imaging Feature Helpful for Diagnosis
Pei-Ying Wei, Nian-Dong Jiang, Jing-Jing Xiang, Chen-Ke Xu, Jin-Wang Ding, Hai-Bin Wang, Ding-Cun Luo & Zhi-Jiang Han
Pages: 2711-2717
Published online: 22 Apr 2020
AbstractforHounsfield Unit Values in ACR TI-RADS 4-5 Thyroid Nodules with Coarse Calcifications: An Important Imaging Feature Helpful for Diagnosis | Full Text | References | PDF (3.8 MB) | EPUB
  • 84 Views
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Article
RETRACTED ARTICLE: miR-489-3p Inhibits Prostate Cancer Progression by Targeting DLX1
Peide Bai, Wei Li, Zhenghua Wan, Yujuan Xiao, Wen Xiao, Xuegang Wang, Zhun Wu, Kaiyan Zhang, Yongfeng Wang, Bin Chen, Jinchun Xing & Tao Wang
Pages: 2719-2729
Published online: 23 Apr 2020
AbstractforRETRACTED ARTICLE: miR-489-3p Inhibits Prostate Cancer Progression by Targeting DLX1 | PDF (9.3 MB)
  • 20 Views
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Review

Review Article
BRCA Mutations in Pancreas Cancer: Spectrum, Current Management, Challenges and Future Prospects
Winston Wong, Alexander G Raufi, Rachael A Safyan, Susan E Bates & Gulam A Manji
Pages: 2731-2742
Published online: 23 Apr 2020
AbstractforBRCA Mutations in Pancreas Cancer: Spectrum, Current Management, Challenges and Future Prospects | Full Text | References | PDF (444.7 KB) | EPUB
  • 252 Views
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Review Article
Spread Through Air Spaces (STAS) in Lung Cancer: A Multiple-Perspective and Update Review
Meng Jia, Shili Yu, Hongwen Gao & Ping-Li Sun
Pages: 2743-2752
Published online: 23 Apr 2020
AbstractforSpread Through Air Spaces (STAS) in Lung Cancer: A Multiple-Perspective and Update Review | Full Text | References | PDF (2.3 MB) | EPUB
  • 196 Views
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Original Research

Article
RETRACTED ARTICLE: Circular RNA Circ_0025033 Promotes the Evolvement of Ovarian Cancer Through the Regulation of miR-330-5p/KLK4 Axis
Hailing Cheng, Ning Wang, Jun Tian, Yanyun Li, Lu Ren & Zhenyu Shi
Pages: 2753-2765
Published online: 23 Apr 2020
AbstractforRETRACTED ARTICLE: Circular RNA Circ_0025033 Promotes the Evolvement of Ovarian Cancer Through the Regulation of miR-330-5p/KLK4 Axis | PDF (9.2 MB)
  • 12 Views
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Article
Prognostic Value of the Combination of CEA and Fibrinogen/Albumin Ratio in Resectable Gastric Cancer
Junbin Zhang, Jiayin Ruan, Weibin Wang, Yimin Lu, Haiyong Wang, Xiongfei Yu, Haohao Wang & Lisong Teng
Pages: 2767-2775
Published online: 23 Apr 2020
AbstractforPrognostic Value of the Combination of CEA and Fibrinogen/Albumin Ratio in Resectable Gastric Cancer | Full Text | References | PDF (2 MB) | EPUB
  • 106 Views
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Article
Long Non-Coding RNA UCA1 Modulates Paclitaxel Resistance in Breast Cancer via miR-613/CDK12 Axis
Chunhong Liu, Feng Jiang, Xueqin Zhang & Xiulong Xu
Pages: 2777-2788
Published online: 23 Apr 2020
AbstractforLong Non-Coding RNA UCA1 Modulates Paclitaxel Resistance in Breast Cancer via miR-613/CDK12 Axis | Full Text | References | PDF (7.3 MB) | EPUB
  • 92 Views
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Article
Circular RNA circNRIP1 Sponges microRNA-138-5p to Maintain Hypoxia-Induced Resistance to 5-Fluorouracil Through HIF-1α-Dependent Glucose Metabolism in Gastric Carcinoma
Guangsong Xu, Mingliang Li, Jiang Wu, Chunhong Qin, Yin Tao & Hongjie He
Pages: 2789-2802
Published online: 23 Apr 2020
AbstractforCircular RNA circNRIP1 Sponges microRNA-138-5p to Maintain Hypoxia-Induced Resistance to 5-Fluorouracil Through HIF-1α-Dependent Glucose Metabolism in Gastric Carcinoma | Full Text | References | PDF (8.5 MB) | EPUB
  • 119 Views
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Article
Psoralen Suppresses Cisplatin-Mediated Resistance and Induces Apoptosis of Gastric Adenocarcinoma by Disruption of the miR196a-HOXB7-HER2 Axis
Lei Jin, Xue-Mei Ma, Ting-Ting Wang, Yao Yang, Nan Zhang, Na Zeng, Zhi-Gang Bai, Jie Yin, Jun Zhang, Guo-Qian Ding & Zhong-Tao Zhang
Pages: 2803-2827
Published online: 23 Apr 2020
AbstractforPsoralen Suppresses Cisplatin-Mediated Resistance and Induces Apoptosis of Gastric Adenocarcinoma by Disruption of the miR196a-HOXB7-HER2 Axis | Full Text | References | PDF (22.7 MB) | EPUB
  • 77 Views
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Article
The Synchronous Presence of Multiple Myelomas and Other Primary Malignant Tumors: Case Series with Literature Review
Ning Li, Xiyang Liu, Yongping Song, Suxia Luo & Baijun Fang
Pages: 2829-2838
Published online: 24 Apr 2020
AbstractforThe Synchronous Presence of Multiple Myelomas and Other Primary Malignant Tumors: Case Series with Literature Review | Full Text | References | PDF (1.6 MB) | EPUB
  • 107 Views
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Article
Clinical Analysis and Prognostic Significance of Hepatitis B Virus Infections with Diffuse Large B-Cell Lymphoma
Xindan Kang, Li Bai, Chun Han & Xiaoguang Qi
Pages: 2839-2851
Published online: 24 Apr 2020
AbstractforClinical Analysis and Prognostic Significance of Hepatitis B Virus Infections with Diffuse Large B-Cell Lymphoma | Full Text | References | PDF (3.4 MB) | EPUB
  • 78 Views
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Article
Glycyrrhizic Acid Inhibits Proliferation of Gastric Cancer Cells by Inducing Cell Cycle Arrest and Apoptosis
Hao Wang, Xuhui Ge, Huiheng Qu, Ning Wang, Jiawen Zhou, Wenjing Xu, Jingjing Xie, Yongping Zhou, Liqing Shi, Zhongke Qin, Zhuang Jiang, Wenjie Yin & Jiazeng Xia
Pages: 2853-2861
Published online: 24 Apr 2020
AbstractforGlycyrrhizic Acid Inhibits Proliferation of Gastric Cancer Cells by Inducing Cell Cycle Arrest and Apoptosis | Full Text | References | PDF (5.2 MB) | EPUB
  • 217 Views
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Article
Evaluation of Concordance Between Deficient Mismatch Repair and Microsatellite Instability Testing and Their Association with Clinicopathological Features in Colorectal Cancer
Huili Bai, Rong Wang, Wei Cheng, Yifan Shen, Haijun Li, Wei Xia, Zhenglin Ding & Yuhong Zhang
Pages: 2863-2873
Published online: 24 Apr 2020
AbstractforEvaluation of Concordance Between Deficient Mismatch Repair and Microsatellite Instability Testing and Their Association with Clinicopathological Features in Colorectal Cancer | Full Text | References | PDF (4.2 MB) | EPUB
  • 132 Views
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Article
Evodiamine Exerts Anticancer Effects Against 143B and MG63 Cells Through the Wnt/β-Catenin Signaling Pathway
Shengdong Yang, Jin Chen, Tao Tan, Nan Wang, Yanran Huang, Yuping Wang, Xiaohui Yuan, Ping Zhang, Jinyong Luo & Xiaoji Luo
Pages: 2875-2888
Published online: 28 Apr 2020
AbstractforEvodiamine Exerts Anticancer Effects Against 143B and MG63 Cells Through the Wnt/β-Catenin Signaling Pathway | Full Text | References | PDF (9.8 MB) | EPUB
  • 89 Views
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Article
Comparative Diagnostic Evaluation with Contrast-Enhanced Ultrasound, Computed Tomography and Magnetic Resonance Imaging in Patients with Pancreatic Cystic Neoplasms
Ya Sun, Shuo Yang, Erpeng Qi, Fangyi Liu, Fubo Zhou, Yuhan Lu, Ping Liang, Huiyi Ye & Xiaoling Yu
Pages: 2889-2898
Published online: 28 Apr 2020
AbstractforComparative Diagnostic Evaluation with Contrast-Enhanced Ultrasound, Computed Tomography and Magnetic Resonance Imaging in Patients with Pancreatic Cystic Neoplasms | Full Text | References | PDF (3.8 MB) | EPUB
  • 91 Views
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Article
Homer1 is a Potential Biomarker for Prognosis in Human Colorectal Carcinoma, Possibly in Association with G3BP1 Signaling
Xiangrong Cui, Hongping Liang, Chonghua Hao & Xuan Jing
Pages: 2899-2909
Published online: 28 Apr 2020
AbstractforHomer1 is a Potential Biomarker for Prognosis in Human Colorectal Carcinoma, Possibly in Association with G3BP1 Signaling | Full Text | References | PDF (10.4 MB) | EPUB
  • 73 Views
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Article
Hepatic Arterial Infusion Combined with Systemic Chemotherapy for Patients with Extensive Liver Metastases from Gastric Cancer
Weiguang Qiang, Hongbing Shi, Jun Wu, Mei Ji & Changping Wu
Pages: 2911-2916
Published online: 29 Apr 2020
AbstractforHepatic Arterial Infusion Combined with Systemic Chemotherapy for Patients with Extensive Liver Metastases from Gastric Cancer | Full Text | References | PDF (323.2 KB) | EPUB
  • 72 Views
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Article
Plasmatic circRNA Predicting the Occurrence of Human Glioblastoma
Ainian Chen, Lingling Zhong, Keju Ju, Ting Lu, Jia Lv & Hua Cao
Pages: 2917-2923
Published online: 29 Apr 2020
AbstractforPlasmatic circRNA Predicting the Occurrence of Human Glioblastoma | Full Text | References | PDF (3.6 MB) | EPUB
  • 77 Views
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Article
MiR-27a-3p Regulated the Aggressive Phenotypes of Cervical Cancer by Targeting FBXW7
Wei Ben, Guangmei Zhang, Yangang Huang & Yuhui Sun
Pages: 2925-2935
Published online: 29 Apr 2020
AbstractforMiR-27a-3p Regulated the Aggressive Phenotypes of Cervical Cancer by Targeting FBXW7 | Full Text | References | PDF (6 MB) | EPUB
  • 104 Views
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Article
Expression Pattern and Prognostic Utility of PME-1 in Patients with Hepatocellular Carcinoma
Baoying Du, Hongfeng Liao & Sheng Zhang
Pages: 2937-2945
Published online: 29 Apr 2020
AbstractforExpression Pattern and Prognostic Utility of PME-1 in Patients with Hepatocellular Carcinoma | Full Text | References | PDF (4 MB) | EPUB
  • 70 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA DLGAP1-AS1 Promotes the Aggressive Behavior of Gastric Cancer by Acting as a ceRNA for microRNA-628-5p and Raising Astrocyte Elevated Gene 1 Expression
Jiying Deng, Qin Zhang, Lianwei Lu & Chunxia Fan
Pages: 2947-2960
Published online: 29 Apr 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA DLGAP1-AS1 Promotes the Aggressive Behavior of Gastric Cancer by Acting as a ceRNA for microRNA-628-5p and Raising Astrocyte Elevated Gene 1 Expression | PDF (9.3 MB)
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Review

Review Article
The Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios as New Prognostic Factors in Hematological Malignancies – A Narrative Review
Paulina Stefaniuk, Agnieszka Szymczyk & Monika Podhorecka
Pages: 2961-2977
Published online: 29 Apr 2020
AbstractforThe Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios as New Prognostic Factors in Hematological Malignancies – A Narrative Review | Full Text | References | PDF (554.3 KB) | EPUB
  • 374 Views
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Original Research

Article
Deep Learning in CT Images: Automated Pulmonary Nodule Detection for Subsequent Management Using Convolutional Neural Network
Yi-Ming Xu, Teng Zhang, Hai Xu, Liang Qi, Wei Zhang, Yu-Dong Zhang, Da-Shan Gao, Mei Yuan & Tong-Fu Yu
Pages: 2979-2992
Published online: 29 Apr 2020
AbstractforDeep Learning in CT Images: Automated Pulmonary Nodule Detection for Subsequent Management Using Convolutional Neural Network | Full Text | References | PDF (3.6 MB) | EPUB
  • 114 Views
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Article
MicroRNA-155 Suppresses the Translation of p38 and Impairs the Functioning of Dendritic Cells in Endometrial Cancer Mice
Jianjun Jia, Xiaomao Li, Suiqun Guo & Xingmei Xie
Pages: 2993-3002
Published online: 30 Apr 2020
AbstractforMicroRNA-155 Suppresses the Translation of p38 and Impairs the Functioning of Dendritic Cells in Endometrial Cancer Mice | Full Text | References | PDF (4.2 MB) | EPUB
  • 73 Views
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Article
Clinicopathological Characteristics and Mutational Profiling of Adult T-Cell Lymphoblastic Lymphoma in a Chinese Population
Feili Chen, Diwen Pang, Hanguo Guo, Xinmiao Jiang, Sichu Liu, Ling Huang, Xiaojuan Wei, Zhanli Liang, Xiaoxia Wang & Wenyu Li
Pages: 3003-3012
Published online: 30 Apr 2020
AbstractforClinicopathological Characteristics and Mutational Profiling of Adult T-Cell Lymphoblastic Lymphoma in a Chinese Population | Full Text | References | PDF (1.5 MB) | EPUB
  • 66 Views
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Article
Effect and Mechanism of miR-26a-5p on Proliferation and Apoptosis of Hepatocellular Carcinoma Cells
Wen-Jing Zhu, Ying Yan, Jiu-Wei Zhang, Yan-Dong Tang & Bo Han
Pages: 3013-3022
Published online: 30 Apr 2020
AbstractforEffect and Mechanism of miR-26a-5p on Proliferation and Apoptosis of Hepatocellular Carcinoma Cells | Full Text | References | PDF (5.9 MB) | EPUB
  • 85 Views
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Article
Gene Therapy with Cytosine Deaminase and Endostatin Fusion Gene Mediated by Endothelial Progenitor Cells in Hepatomas
Yue-Lin Zhang, Tan-Yang Zhou, Jing Ai, Sheng-Qun Chen, Feng Chen, Chun-Hui Nie, Xin-Hua Chen, Guan-Hui Zhou, Hong-Liang Wang, Tong-Yin Zhu, Bao-Quan Wang, Zi-Niu Yu, Li Jing, Li-Ming Wu, Shu-Sen Zheng & Jun-Hui Sun
Pages: 3023-3031
Published online: 30 Apr 2020
AbstractforGene Therapy with Cytosine Deaminase and Endostatin Fusion Gene Mediated by Endothelial Progenitor Cells in Hepatomas | Full Text | References | PDF (10 MB) | EPUB
  • 66 Views
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Review

Review Article
Role of GSDMB in Pyroptosis and Cancer
Lisha Li, Yanjing Li & Yuxian Bai
Pages: 3033-3043
Published online: 30 Apr 2020
AbstractforRole of GSDMB in Pyroptosis and Cancer | Full Text | References | PDF (2.6 MB) | EPUB
  • 173 Views
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Original Research

Article
Accuracy of Sentinel Lymph Node Biopsy in Breast Cancer: Pitfalls in the Application of Single Tracers
Jiqiao Yang, Li Xu, Pengcheng Liu, Zhenggui Du, Jie Chen, Faqing Liang, Quanyi Long, Di Zhang, Helin Zeng & Qing Lv
Pages: 3045-3051
Published online: 01 May 2020
AbstractforAccuracy of Sentinel Lymph Node Biopsy in Breast Cancer: Pitfalls in the Application of Single Tracers | Full Text | References | PDF (250.1 KB) | EPUB
  • 122 Views
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Article
HAND2-AS1 Inhibits Gastric Adenocarcinoma Cells Proliferation and Aerobic Glycolysis via miRNAs Sponge
Zhiyuan Xu, Hang Lv, Yiping Wang, Can Hu, Shangqi Chen, Yian Du, Chengwei Shi & Xiangdong Cheng
Pages: 3053-3068
Published online: 01 May 2020
AbstractforHAND2-AS1 Inhibits Gastric Adenocarcinoma Cells Proliferation and Aerobic Glycolysis via miRNAs Sponge | Full Text | References | PDF (9.9 MB) | EPUB
  • 103 Views
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Article
NUDT21 Suppresses Breast Cancer Tumorigenesis Through Regulating CPSF6 Expression
Bi-Jun Wang, Da-Chao Liu, Qian-Ying Guo, Xiao-Wen Han, Xiao-Min Bi, Hao Wang, Zheng-Sheng Wu & Wen-Yong Wu
Pages: 3069-3078
Published online: 01 May 2020
AbstractforNUDT21 Suppresses Breast Cancer Tumorigenesis Through Regulating CPSF6 Expression | Full Text | References | PDF (4.6 MB) | EPUB
  • 101 Views
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Erratum

Correction
Selective Use of Concurrent Chemotherapy in Elderly Cervical Cancer Patients Treated with Definitive Radiotherapy: Experience from Two Institutions [Erratum]
Page: 3079
Published online: 04 May 2020
CitationforSelective Use of Concurrent Chemotherapy in Elderly Cervical Cancer Patients Treated with Definitive Radiotherapy: Experience from Two Institutions [Erratum] | Full Text | PDF (149.8 KB) | EPUB
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Original Research

Article
Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway
Guangxiu Guo, Sujuan Dai & Qing Chen
Pages: 3081-3089
Published online: 04 May 2020
AbstractforLong Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway | Full Text | References | PDF (3.8 MB) | EPUB
  • 81 Views
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Article
Long Non-Coding RNA TTN-AS1 Serves as a Competing Endogenous RNA of miR-195 to Facilitate Clear Cell Renal Cell Carcinoma Progression
Keng Lin, Hao Chen, Chunyan Su, Huanjin Zhu, Changchun Lai & Yaling Shi
Pages: 3091-3097
Published online: 04 May 2020
AbstractforLong Non-Coding RNA TTN-AS1 Serves as a Competing Endogenous RNA of miR-195 to Facilitate Clear Cell Renal Cell Carcinoma Progression | Full Text | References | PDF (3.4 MB) | EPUB
  • 59 Views
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Article
Plasma cfDNA as a Potential Biomarker to Evaluate the Efficacy of Chemotherapy in Gastric Cancer
Yuejiao Zhong, Qingyu Fan, Zhaofei Zhou, Yajing Wang, Kang He & Jianwei Lu
Pages: 3099-3106
Published online: 05 May 2020
AbstractforPlasma cfDNA as a Potential Biomarker to Evaluate the Efficacy of Chemotherapy in Gastric Cancer | Full Text | References | PDF (4.2 MB) | EPUB
  • 100 Views
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Article
DW-MRI-Guided Dose Escalation Improves Local Control of Locally Advanced Nasopharyngeal Carcinoma Treated with Chemoradiotherapy
Yecai Huang, Mei Feng, Xuegang Yang, Jie Zhou, Lu Li, Ke Xu, Guohui Xu & Jinyi Lang
Pages: 3107-3116
Published online: 06 May 2020
AbstractforDW-MRI-Guided Dose Escalation Improves Local Control of Locally Advanced Nasopharyngeal Carcinoma Treated with Chemoradiotherapy | Full Text | References | PDF (2.7 MB) | EPUB
  • 87 Views
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Article
Active Monomer RTR-1 Derived from the Root of Rhodomyrtus tomentosa Induces Apoptosis in Gastric Carcinoma Cells by Inducing ER Stress and Inhibiting the STAT3 Signaling Pathway
Xiangqiang Zhang, Jinxia Cheng, Peiyan He, Jinyan Zhu, Zhixian Chen, Shenyu Miao, Guocai Wang, Jianwei Jiang & Yuechun Wang
Pages: 3117-3129
Published online: 05 May 2020
AbstractforActive Monomer RTR-1 Derived from the Root of Rhodomyrtus tomentosa Induces Apoptosis in Gastric Carcinoma Cells by Inducing ER Stress and Inhibiting the STAT3 Signaling Pathway | Full Text | References | PDF (6.4 MB) | EPUB
  • 89 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA LINC00173 Promotes the Malignancy of Melanoma by Promoting the Expression of IRS4 Through Competitive Binding to microRNA-493
Fan Yang, Pengzhen Lei, Weihui Zeng, Jianwu Gao & Na Wu
Pages: 3131-3144
Published online: 05 May 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA LINC00173 Promotes the Malignancy of Melanoma by Promoting the Expression of IRS4 Through Competitive Binding to microRNA-493 | PDF (9.2 MB)
  • 22 Views
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Article
Therapeutic Effect of Trastuzumab in Neoadjuvant-Treated HER2-Positive Breast Cancer with Low Infiltrating Level of Tumor-Infiltrating Lymphocytes
Shiwei Liu, Exian Mou, Shiyan Zeng, Lu Wang, Hao Dong, Juan Ji, Hong Yang, Junjie Li, Hao Wang, Hui Li & Jia Xu
Pages: 3145-3153
Published online: 05 May 2020
AbstractforTherapeutic Effect of Trastuzumab in Neoadjuvant-Treated HER2-Positive Breast Cancer with Low Infiltrating Level of Tumor-Infiltrating Lymphocytes | Full Text | References | PDF (2.1 MB) | EPUB
  • 61 Views
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Article
Primary Causes of Death in Patients with Non-Hodgkin’s Lymphoma: A Retrospective Cohort Study
Mei Mei, Yingjun Wang, Wenting Song & Mingzhi Zhang
Pages: 3155-3162
Published online: 06 May 2020
AbstractforPrimary Causes of Death in Patients with Non-Hodgkin’s Lymphoma: A Retrospective Cohort Study | Full Text | References | PDF (2 MB) | EPUB
  • 131 Views
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Article
Drug-Related Hypertension Associated with the Efficacy of Apatinib on Hepatocellular Carcinoma
XueJiao Yang, ZhenYu Hou, KeYun Zhu, Su Zhang, XiaoYing Gu, ZhiWei Wang, Han Mu, HongYuan Zhou, Ping Chen, XiaoLin Zhu, YunLong Cui, Qiang Li, HuiKai Li & Ti Zhang
Pages: 3163-3173
Published online: 06 May 2020
AbstractforDrug-Related Hypertension Associated with the Efficacy of Apatinib on Hepatocellular Carcinoma | Full Text | References | PDF (890.5 KB) | EPUB
  • 80 Views
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Review

Review Article
Monitoring of Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia: Recent Advances
Cosimo Cumbo, Luisa Anelli, Giorgina Specchia & Francesco Albano
Pages: 3175-3189
Published online: 06 May 2020
AbstractforMonitoring of Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia: Recent Advances | Full Text | References | PDF (2.5 MB) | EPUB
  • 293 Views
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Original Research

Article
Differentiation of Treatment-Related Effects from Glioma Recurrence Using Machine Learning Classifiers Based Upon Pre-and Post-Contrast T1WI and T2 FLAIR Subtraction Features: A Two-Center Study
Xin-Yi Gao, Yi-Da Wang, Shi-Man Wu, Wen-Ting Rui, De-Ning Ma, Yi Duan, An-Ni Zhang, Zhen-Wei Yao, Guang Yang & Yan-Ping Yu
Pages: 3191-3201
Published online: 07 May 2020
AbstractforDifferentiation of Treatment-Related Effects from Glioma Recurrence Using Machine Learning Classifiers Based Upon Pre-and Post-Contrast T1WI and T2 FLAIR Subtraction Features: A Two-Center Study | Full Text | References | PDF (3.9 MB) | EPUB
  • 137 Views
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Article
Influence of Body Mass Index on Survival and Prognosis in Squamous Cell Carcinoma of Head and Neck
Peng Li, Liyan Sun & Luyan Sun
Pages: 3203-3210
Published online: 07 May 2020
AbstractforInfluence of Body Mass Index on Survival and Prognosis in Squamous Cell Carcinoma of Head and Neck | Full Text | References | PDF (1,021.8 KB) | EPUB
  • 78 Views
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Article
SNHG7 Contributes to the Progression of Non-Small-Cell Lung Cancer via the SNHG7/miR-181a-5p/E2F7 Axis
Liming Wang, Lili Zhang & Liwei Wang
Pages: 3211-3222
Published online: 07 May 2020
AbstractforSNHG7 Contributes to the Progression of Non-Small-Cell Lung Cancer via the SNHG7/miR-181a-5p/E2F7 Axis | Full Text | References | PDF (7.4 MB) | EPUB
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Article
WD Repeat Domain 5 Promotes Invasion, Metastasis and Tumor Growth in Glioma Through Up-Regulated Zinc Finger E-Box Binding Homeobox 1 Expression
Bin Dai, Zhiyong Xiao, Guangtong Zhu, Beibei Mao, Hui Huang, Feng Guan, Zhenyang Lin, Weicheng Peng, Xin Liang, Bolun Zhang & Zhiqiang Hu
Pages: 3223-3235
Published online: 08 May 2020
AbstractforWD Repeat Domain 5 Promotes Invasion, Metastasis and Tumor Growth in Glioma Through Up-Regulated Zinc Finger E-Box Binding Homeobox 1 Expression | Full Text | References | PDF (10.3 MB) | EPUB
  • 72 Views
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Article
Indocyanine Green Clearance Test for the Preoperative Assessment of Chemotherapy-Related Hepatic Injury in Patients with Colorectal Liver Metastasis
Li-Jun Wang, Xiao-Luan Yan, Juan Li, Kun Wang & Bao-Cai Xing
Pages: 3237-3245
Published online: 08 May 2020
AbstractforIndocyanine Green Clearance Test for the Preoperative Assessment of Chemotherapy-Related Hepatic Injury in Patients with Colorectal Liver Metastasis | Full Text | References | PDF (1.9 MB) | EPUB
  • 66 Views
  • 5 CrossRef citations
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Article
DNAM1 and 2B4 Costimulatory Domains Enhance the Cytotoxicity of Anti-GPC3 Chimeric Antigen Receptor-Modified Natural Killer Cells Against Hepatocellular Cancer Cells in vitro
Yao Huang, Jianxing Zeng, Teng Liu, Qingyi Xu, Xianglin Song & Jinhua Zeng
Pages: 3247-3255
Published online: 08 May 2020
AbstractforDNAM1 and 2B4 Costimulatory Domains Enhance the Cytotoxicity of Anti-GPC3 Chimeric Antigen Receptor-Modified Natural Killer Cells Against Hepatocellular Cancer Cells in vitro | Full Text | References | PDF (5.2 MB) | EPUB
  • 151 Views
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Retraction

Retraction
Protocadherin 17 Is a Tumor Suppressor and Is Frequently Methylated in Nasopharyngeal Carcinoma [Retraction]
Page: 3257
Published online: 11 May 2020
CitationforProtocadherin 17 Is a Tumor Suppressor and Is Frequently Methylated in Nasopharyngeal Carcinoma [Retraction] | Full Text | PDF (150.9 KB) | EPUB
  • 64 Views
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Original Research

Article
The Association Between Immune Characteristic and Clinical Pathology in Chinese Patients with Adenocarcinoma of Esophagogastric Junction
Yangyang Wang, Shuchang Wang, Chunchao Zhu, Hui Cao, Zizhen Zhang & Enhao Zhao
Pages: 3259-3269
Published online: 11 May 2020
AbstractforThe Association Between Immune Characteristic and Clinical Pathology in Chinese Patients with Adenocarcinoma of Esophagogastric Junction | Full Text | References | PDF (5.4 MB) | EPUB
  • 74 Views
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Article
Prognostic Significance of the Preoperative Lymphocyte to Monocyte Ratio in Patients with Gallbladder Carcinoma
Weiyu Xu, Xiaoqian Wu, Xuezhu Wang, Si Yu, Gang Xu, Jianping Xiong, Junwei Zhang, Xinting Sang, Yongchang Zheng & Wei Liu
Pages: 3271-3283
Published online: 11 May 2020
AbstractforPrognostic Significance of the Preoperative Lymphocyte to Monocyte Ratio in Patients with Gallbladder Carcinoma | Full Text | References | PDF (2.3 MB) | EPUB
  • 64 Views
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Article
Circular RNA CircPRMT5 Accelerates Proliferation and Invasion of Papillary Thyroid Cancer Through Regulation of miR-30c/E2F3 Axis
Cheng Xue, Yi Cheng, Jinyou Wu, Kongliang Ke, Chundi Miao, Enfu Chen & Luqing Zhang
Pages: 3285-3291
Published online: 11 May 2020
AbstractforCircular RNA CircPRMT5 Accelerates Proliferation and Invasion of Papillary Thyroid Cancer Through Regulation of miR-30c/E2F3 Axis | Full Text | References | PDF (4.8 MB) | EPUB
  • 84 Views
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Article
Tyrosine Kinase Inhibitor-Related Hepatotoxicity in Patients with Advanced Lung Adenocarcinoma: A Real-World Retrospective Study
Jie Qian, Xueyan Zhang, Bo Zhang, Bo Yan, Lin Wang, Ping Gu, Weimin Wang, Huimin Wang & Baohui Han
Pages: 3293-3299
Published online: 11 May 2020
AbstractforTyrosine Kinase Inhibitor-Related Hepatotoxicity in Patients with Advanced Lung Adenocarcinoma: A Real-World Retrospective Study | Full Text | References | PDF (1.7 MB) | EPUB
  • 99 Views
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Article
Gene Expression Signature to Predict Prognosis and Adjuvant Chemosensitivity of Colorectal Cancer Patients
Jianxia Li, Jianwei Zhang, Huabin Hu, Yue Cai, Jiayu Ling, Zehua Wu & Yanhong Deng
Pages: 3301-3310
Published online: 11 May 2020
AbstractforGene Expression Signature to Predict Prognosis and Adjuvant Chemosensitivity of Colorectal Cancer Patients | Full Text | References | PDF (5.1 MB) | EPUB
  • 82 Views
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Article
SP1-Induced Upregulation of lncRNA LINC00514 Promotes Tumor Proliferation and Metastasis in Osteosarcoma by Regulating miR-708
Li-Dong Mi, Chuan-Xiu Sun, Sheng-Wei He & Guang-Yu Du
Pages: 3311-3322
Published online: 11 May 2020
AbstractforSP1-Induced Upregulation of lncRNA LINC00514 Promotes Tumor Proliferation and Metastasis in Osteosarcoma by Regulating miR-708 | Full Text | References | PDF (5.5 MB) | EPUB
  • 71 Views
  • 10 CrossRef citations
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Article
Nimotuzumab Combined with Induction Chemotherapy and Concurrent Chemoradiotherapy in Unresectable Locally Advanced Hypopharyngeal Carcinoma: A Single Institution Experience in China
Xin Tian, Ying Xuan, Rong Wu & Song Gao
Pages: 3323-3329
Published online: 11 May 2020
AbstractforNimotuzumab Combined with Induction Chemotherapy and Concurrent Chemoradiotherapy in Unresectable Locally Advanced Hypopharyngeal Carcinoma: A Single Institution Experience in China | Full Text | References | PDF (987.8 KB) | EPUB
  • 71 Views
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Corrigendum

Correction
Targeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer [Corrigendum]
Pages: 3331-3332
Published online: 12 May 2020
CitationforTargeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer [Corrigendum] | Full Text | PDF (2 MB) | EPUB
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Original Research

Article
Computed Tomography-Guided Percutaneous Cryoablation for ‎ Subcardiac Hepatocellular Carcinoma: Safety, Efficacy, Therapeutic Results and Risk Factors for Survival Outcomes
Chunhou Qi, Hongfei Gao, Qinghua Zhao & Lei Zhang
Pages: 3333-3342
Published online: 12 May 2020
AbstractforComputed Tomography-Guided Percutaneous Cryoablation for ‎ Subcardiac Hepatocellular Carcinoma: Safety, Efficacy, Therapeutic Results and Risk Factors for Survival Outcomes | Full Text | References | PDF (2 MB) | EPUB
  • 101 Views
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Article
Upregulation of miR-340 Inhibits Tumor Growth and Mesenchymal Transition via Targeting c-MET in Glioblastoma
Ning Lin, Wentao Li, Xiefeng Wang, Shiqiang Hou, Dong Yu, Xingyuan Zhao, Chunjing Jin, Guoquan Yao, Wei Yan & Yongping You
Pages: 3343-3352
Published online: 12 May 2020
AbstractforUpregulation of miR-340 Inhibits Tumor Growth and Mesenchymal Transition via Targeting c-MET in Glioblastoma | Full Text | References | PDF (8.8 MB) | EPUB
  • 83 Views
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Article
LINC00963 Functions as an Oncogene in Bladder Cancer by Regulating the miR-766-3p/MTA1 Axis
Ning Zhou, Xiaofei Zhu & Libo Man
Pages: 3353-3361
Published online: 12 May 2020
AbstractforLINC00963 Functions as an Oncogene in Bladder Cancer by Regulating the miR-766-3p/MTA1 Axis | Full Text | References | PDF (6.3 MB) | EPUB
  • 81 Views
  • 14 CrossRef citations
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Article
Long Noncoding RNA LINC00173 Contributes to the Growth, Invasiveness and Chemo-Resistance of Colorectal Cancer Through Regulating miR-765/PLP2 Axis
Yanhui Yu, Xiuyun Lu, Chuandong Yang & Fengxiang Yin
Pages: 3363-3369
Published online: 12 May 2020
AbstractforLong Noncoding RNA LINC00173 Contributes to the Growth, Invasiveness and Chemo-Resistance of Colorectal Cancer Through Regulating miR-765/PLP2 Axis | Full Text | References | PDF (4.1 MB) | EPUB
  • 187 Views
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Article
Predictive Factors for Level V Lymph Node Metastases in Papillary Thyroid Carcinoma with BRAFV600E Mutation and Clinicopathological Features
Gui-you Li, Hai-long Tan, Pei Chen, Hui-Yu Hu, Mian Liu, Deng-jie Ou-yang, Rooh-afza Khushbu, Deepak Pun, Jin-dong Li, Zhi-peng Zhang, Qiong Yang, Peng Huang & Shi Chang
Pages: 3371-3378
Published online: 13 May 2020
AbstractforPredictive Factors for Level V Lymph Node Metastases in Papillary Thyroid Carcinoma with BRAFV600E Mutation and Clinicopathological Features | Full Text | References | PDF (812.9 KB) | EPUB
  • 68 Views
  • 3 CrossRef citations
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Article
Improved ADM Penetration Distance and Therapeutic Efficiency in a Rabbit VX2 Liver Cancer Model by Relaxin Infusion Combined with Transcatheter Chemoembolization Through Hepatic Artery
Fu Xiong, Yanyan Cao, Xiaopeng Guo, Hongsen Zhang, Jihua Wang, Bin Xiong, Bin Liang & Chuansheng Zheng
Pages: 3379-3388
Published online: 13 May 2020
AbstractforImproved ADM Penetration Distance and Therapeutic Efficiency in a Rabbit VX2 Liver Cancer Model by Relaxin Infusion Combined with Transcatheter Chemoembolization Through Hepatic Artery | Full Text | References | PDF (6.7 MB) | EPUB
  • 70 Views
  • 2 CrossRef citations
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Article
Identification of High-Frequency Methylation Sites in RNF180 Promoter Region Affecting Expression and Their Relationship with Prognosis of Gastric Cancer
Fang Han, Shuang Liu, Jingjing Jing, Hao Li, Yuan Yuan & Li-Ping Sun
Pages: 3389-3399
Published online: 13 May 2020
AbstractforIdentification of High-Frequency Methylation Sites in RNF180 Promoter Region Affecting Expression and Their Relationship with Prognosis of Gastric Cancer | Full Text | References | PDF (2.7 MB) | EPUB
  • 76 Views
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Article
LncRNA LUADT1 Promotes Oral Squamous Cell Carcinoma Cell Proliferation by Regulating miR-34a/GAS1 Axis
Lirong Gao, Siming Wang, Junru Meng & Yugang Sun
Pages: 3401-3407
Published online: 13 May 2020
AbstractforLncRNA LUADT1 Promotes Oral Squamous Cell Carcinoma Cell Proliferation by Regulating miR-34a/GAS1 Axis | Full Text | References | PDF (4.6 MB) | EPUB
  • 73 Views
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Article
Efficacy and Safety of Anlotinib in Advanced Non-Small Cell Lung Cancer: A Real-World Study
Kun Zhang, Xiya Ma, Hongjun Gao, Hong Wang, Haifeng Qin, Shaoxing Yang & Xiaoqing Liu
Pages: 3409-3417
Published online: 13 May 2020
AbstractforEfficacy and Safety of Anlotinib in Advanced Non-Small Cell Lung Cancer: A Real-World Study | Full Text | References | PDF (3.3 MB) | EPUB
  • 102 Views
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Article
Toosendanin Suppresses Glioma Progression Property and Induces Apoptosis by Regulating miR-608/Notch Axis
Qiong Wang, Zeng Wang, Guilan Hou & Ping Huang
Pages: 3419-3431
Published online: 13 May 2020
AbstractforToosendanin Suppresses Glioma Progression Property and Induces Apoptosis by Regulating miR-608/Notch Axis | Full Text | References | PDF (11.7 MB) | EPUB
  • 68 Views
  • 15 CrossRef citations
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Article
Dynamic Changes in the Neutrophil-to-Lymphocyte Ratio Predict the Prognosis of Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization
Hongyu Wang, Chuyang Lin, Wenzhe Fan, Jiang Zhang, Yingqiang Zhang, Wang Yao & Jiaping Li
Pages: 3433-3444
Published online: 14 May 2020
AbstractforDynamic Changes in the Neutrophil-to-Lymphocyte Ratio Predict the Prognosis of Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization | Full Text | References | PDF (4 MB) | EPUB
  • 69 Views
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Article
Prognostic Factors and Local Treatment Modalities of Small-Cell Carcinoma of the Cervix: An Analysis According to the International Federation of Gynecology and Obstetrics Stage
Ru Huang, Qiyu Gan & Jingxin Cheng
Pages: 3445-3456
Published online: 14 May 2020
AbstractforPrognostic Factors and Local Treatment Modalities of Small-Cell Carcinoma of the Cervix: An Analysis According to the International Federation of Gynecology and Obstetrics Stage | Full Text | References | PDF (5.2 MB) | EPUB
  • 94 Views
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Article
Circ_0000517 Contributes to Hepatocellular Carcinoma Progression by Upregulating TXNDC5 via Sponging miR-1296-5p
Hongliang Zang, Yuhui Li, Xue Zhang & Guomin Huang
Pages: 3457-3468
Published online: 14 May 2020
AbstractforCirc_0000517 Contributes to Hepatocellular Carcinoma Progression by Upregulating TXNDC5 via Sponging miR-1296-5p | Full Text | References | PDF (7.3 MB) | EPUB
  • 88 Views
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Article
The Analysis of the Anti-Tumor Mechanism of Ursolic Acid Using Connectively Map Approach in Breast Cancer Cells Line MCF-7
Weiqiang Guo, Bin Xu, Xiaoxiao Wang, Bo Zheng, Jiahui Du & Songbai Liu
Pages: 3469-3476
Published online: 15 May 2020
AbstractforThe Analysis of the Anti-Tumor Mechanism of Ursolic Acid Using Connectively Map Approach in Breast Cancer Cells Line MCF-7 | Full Text | References | PDF (2.1 MB) | EPUB
  • 170 Views
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Review

Review Article
Current Therapeutic Progress of CDK4/6 Inhibitors in Breast Cancer
Yanmei Wu, Yu Zhang, Hao Pi & Yuan Sheng
Pages: 3477-3487
Published online: 15 May 2020
AbstractforCurrent Therapeutic Progress of CDK4/6 Inhibitors in Breast Cancer | Full Text | References | PDF (967.2 KB) | EPUB
  • 186 Views
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Original Research

Article
miR-665 Suppresses the Epithelial–Mesenchymal Transition and Progression of Gastric Cancer by Targeting CRIM1
Kun-Zhe Wu, Chun-Dong Zhang, Cheng Zhang, Jun-Peng Pei & Dong-Qiu Dai
Pages: 3489-3501
Published online: 15 May 2020
AbstractformiR-665 Suppresses the Epithelial–Mesenchymal Transition and Progression of Gastric Cancer by Targeting CRIM1 | Full Text | References | PDF (10.9 MB) | EPUB
  • 83 Views
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Article
Development and Validation of Pre- and Post-Operative Models to Predict Recurrence After Resection of Solitary Hepatocellular Carcinoma: A Multi-Institutional Study
Ming-Yu Wu, Qian Qiao, Ke Wang, Gu-Wei Ji, Bing Cai & Xiang-Cheng Li
Pages: 3503-3512
Published online: 15 May 2020
AbstractforDevelopment and Validation of Pre- and Post-Operative Models to Predict Recurrence After Resection of Solitary Hepatocellular Carcinoma: A Multi-Institutional Study | Full Text | References | PDF (4.5 MB) | EPUB
  • 67 Views
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Article
Apatinib for Treatment of Inoperable Metastatic or Locally Advanced Chondrosarcoma: What We Can Learn About the Biological Behavior of Chondrosarcoma from a Two-Center Study
Lu Xie, Jie Xu, Xin Sun, Kuisheng Liu, Xiaowei Li, Fangzhou He, Xinyu Liu, Jin Gu, Zhe Lv, Rongli Yang, Xiaodong Tang, Taiqiang Yan, Dasen Li, Yi Yang, Sen Dong, Kunkun Sun, Danhua Shen & Wei Guo
Pages: 3513-3525
Published online: 15 May 2020
AbstractforApatinib for Treatment of Inoperable Metastatic or Locally Advanced Chondrosarcoma: What We Can Learn About the Biological Behavior of Chondrosarcoma from a Two-Center Study | Full Text | References | PDF (5.4 MB) | EPUB
  • 127 Views
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Article
Upregulation of Piezo1 Is a Novel Prognostic Indicator in Glioma Patients
Shanqiang Qu, Shuting Li & Zhicheng Hu
Pages: 3527-3536
Published online: 18 May 2020
AbstractforUpregulation of Piezo1 Is a Novel Prognostic Indicator in Glioma Patients | Full Text | References | PDF (5.5 MB) | EPUB
  • 110 Views
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Article
Diosmetin Inhibits Cell Proliferation, Induces Cell Apoptosis and Cell Cycle Arrest in Liver Cancer
Aiqing Ma & Rui Zhang
Pages: 3537-3546
Published online: 18 May 2020
AbstractforDiosmetin Inhibits Cell Proliferation, Induces Cell Apoptosis and Cell Cycle Arrest in Liver Cancer | Full Text | References | PDF (7.8 MB) | EPUB
  • 223 Views
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Review

Review Article
Advances in the Detection Technologies and Clinical Applications of Circulating Tumor DNA in Metastatic Breast Cancer
Hao Liao & Huiping Li
Pages: 3547-3560
Published online: 18 May 2020
AbstractforAdvances in the Detection Technologies and Clinical Applications of Circulating Tumor DNA in Metastatic Breast Cancer | Full Text | References | PDF (1.7 MB) | EPUB
  • 123 Views
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Review Article
SPOCK1 Involvement in Epithelial-to-Mesenchymal Transition: A New Target in Cancer Therapy?
Li-rui Sun, Si-yu Li, Qiu-shi Guo, Wei Zhou & Hong-mei Zhang
Pages: 3561-3569
Published online: 18 May 2020
AbstractforSPOCK1 Involvement in Epithelial-to-Mesenchymal Transition: A New Target in Cancer Therapy? | Full Text | References | PDF (1.5 MB) | EPUB
  • 131 Views
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Original Research

Article
Surgical Treatment of Spinal Cord Compression Caused by Metastatic Small Cell Lung Cancer: Ten Years of Experience in a Single Center
Xin Gao, Kun Zhang, Shuang Cao, Shuming Hou, Tao Wang, Wen Guo, Zheyu Wu, Qi Jia, Tielong Liu & Jianru Xiao
Pages: 3571-3578
Published online: 19 May 2020
AbstractforSurgical Treatment of Spinal Cord Compression Caused by Metastatic Small Cell Lung Cancer: Ten Years of Experience in a Single Center | Full Text | References | PDF (743.5 KB) | EPUB
  • 86 Views
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Article
Anlotinib Exerts Anti-Cancer Effects on KRAS-Mutated Lung Cancer Cell Through Suppressing the MEK/ERK Pathway
Haoyue Hu, Yanyang Liu, Songtao Tan, Xiao Xiao Xie, Jun He, Feng Luo & Li Wang
Pages: 3579-3587
Published online: 19 May 2020
AbstractforAnlotinib Exerts Anti-Cancer Effects on KRAS-Mutated Lung Cancer Cell Through Suppressing the MEK/ERK Pathway | Full Text | References | PDF (7.7 MB) | EPUB
  • 111 Views
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Article
Clinical Features and Prognostic Outcome of Renal Collecting Duct Carcinoma: 12 Cases from a Single Institution
Xiaoyuan Qian, Zhixian Wang, Jiaqiao Zhang, Qing Wang, Peng Zhou, Shaogang Wang, Bo Wang & Can Qian
Pages: 3589-3595
Published online: 19 May 2020
AbstractforClinical Features and Prognostic Outcome of Renal Collecting Duct Carcinoma: 12 Cases from a Single Institution | Full Text | References | PDF (884 KB) | EPUB
  • 87 Views
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Article
Surgical Compliance and Survival Outcomes for Patients with Stage T1-2 Non-Small-Cell Lung Cancer
Siben Wang, Weipu Mao, Yi Wang, Xiuquan Shi, Wei Wang, Lili Dai & Wenping Zhang
Pages: 3597-3610
Published online: 19 May 2020
AbstractforSurgical Compliance and Survival Outcomes for Patients with Stage T1-2 Non-Small-Cell Lung Cancer | Full Text | References | PDF (8.9 MB) | EPUB
  • 76 Views
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Article
circRNA MYLK Accelerates Cervical Cancer via Up-Regulation of RHEB and Activation of mTOR Signaling
Rui Chen, Luning Mao, Rui Shi, Wenjing Wang & Jingxin Cheng
Pages: 3611-3621
Published online: 19 May 2020
AbstractforcircRNA MYLK Accelerates Cervical Cancer via Up-Regulation of RHEB and Activation of mTOR Signaling | Full Text | References | PDF (8 MB) | EPUB
  • 69 Views
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Article
LncRNA PLAC 2 Is Downregulated in Osteosarcoma and Regulates Cancer Cell Proliferation Through miR-93
Xiangran Sun, Ling Yu, Yubo Shi & Weichun Guo
Pages: 3623-3629
Published online: 20 May 2020
AbstractforLncRNA PLAC 2 Is Downregulated in Osteosarcoma and Regulates Cancer Cell Proliferation Through miR-93 | Full Text | References | PDF (359 KB) | EPUB
  • 66 Views
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Article
A PI-RADS-Based New Nomogram for Predicting Clinically Significant Prostate Cancer: A Cohort Study
Yueyue Zhang, Guiqi Zhu, Wenlu Zhao, Chaogang Wei, Tong Chen, Qi Ma, Yongsheng Zhang, Boxin Xue & Junkang Shen
Pages: 3631-3641
Published online: 19 May 2020
AbstractforA PI-RADS-Based New Nomogram for Predicting Clinically Significant Prostate Cancer: A Cohort Study | Full Text | References | PDF (4.9 MB) | EPUB
  • 67 Views
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Article
Isthmic Papillary Thyroid Carcinoma Presents a Unique Pattern of Central Lymph Node Metastasis
Liguang Zhou, Chao Gao, Haipeng Li, Weili Liang, Qingdong Zeng & Bo Chen
Pages: 3643-3650
Published online: 19 May 2020
AbstractforIsthmic Papillary Thyroid Carcinoma Presents a Unique Pattern of Central Lymph Node Metastasis | Full Text | References | PDF (1.1 MB) | EPUB
  • 67 Views
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Review

Review Article
The Diagnosis, Treatment, Prognosis and Molecular Pathology of Borderline Ovarian Tumors: Current Status and Perspectives
Yu Sun, Juan Xu & Xuemei Jia
Pages: 3651-3659
Published online: 19 May 2020
AbstractforThe Diagnosis, Treatment, Prognosis and Molecular Pathology of Borderline Ovarian Tumors: Current Status and Perspectives | Full Text | References | PDF (418.3 KB) | EPUB
  • 346 Views
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Original Research

Article
Knockdown of circRAD18 Mitigates Breast Cancer Progression through the Regulation of miR-613/HK2 Axis
Hongliang Zang, Yuhui Li, Xue Zhang & Guomin Huang
Pages: 3661-3672
Published online: 19 May 2020
AbstractforKnockdown of circRAD18 Mitigates Breast Cancer Progression through the Regulation of miR-613/HK2 Axis | Full Text | References | PDF (7.9 MB) | EPUB
  • 112 Views
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Review

Review Article
The Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer
Changjiu Li, Xian Fu, Huadong He, Chao Chen, Yuyong Wang & Lugeng He
Pages: 3673-3689
Published online: 19 May 2020
AbstractforThe Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer | Full Text | References | PDF (2.4 MB) | EPUB
  • 61 Views
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Original Research

Article
The Effect of Hormone Therapy on the Expression of Prostate Cancer and Multi-Epigenetic Marker Genes in a Population of Iranian Patients
Mahan Mohammadi, Shiva Irani, Iman Salahshourifar, Jalil Hosseini, Afshin Moradi & Farkhondeh Pouresmaeili
Pages: 3691-3697
Published online: 19 May 2020
AbstractforThe Effect of Hormone Therapy on the Expression of Prostate Cancer and Multi-Epigenetic Marker Genes in a Population of Iranian Patients | Full Text | References | PDF (1.7 MB) | EPUB
  • 88 Views
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Review

Review Article
Traditional and Complementary Medicine Use Among Adult Cancer Patients Undergoing Conventional Treatment in Sub-Saharan Africa: A Scoping Review on the Use, Safety and Risks
Amos Deogratius Mwaka, Catherine Abbo & Alison Annet Kinengyere
Pages: 3699-3712
Published online: 20 May 2020
AbstractforTraditional and Complementary Medicine Use Among Adult Cancer Patients Undergoing Conventional Treatment in Sub-Saharan Africa: A Scoping Review on the Use, Safety and Risks | Full Text | References | PDF (433.8 KB) | EPUB
  • 413 Views
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Original Research

Article
With High-Risk Factors, Total Thyroidectomy is Preferred for Thyroid Cancer
Lin Han, Wenlei Li, Yingxue Li, Wenjuan Wen, Yumin Yao & Yongkun Wang
Pages: 3713-3719
Published online: 20 May 2020
AbstractforWith High-Risk Factors, Total Thyroidectomy is Preferred for Thyroid Cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 85 Views
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Review

Review Article
Ramucirumab, A Second-Line Option For Patients With Hepatocellular Carcinoma: A Review Of The Evidence
Emmanuele De Luca, Donatella Marino & Massimo Di Maio
Pages: 3721-3729
Published online: 20 May 2020
AbstractforRamucirumab, A Second-Line Option For Patients With Hepatocellular Carcinoma: A Review Of The Evidence | Full Text | References | PDF (312.6 KB) | EPUB
  • 110 Views
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Original Research

Article
RETRACTED ARTICLE: The Overexpression of Kinesin Superfamily Protein 2A (KIF2A) was Associated with the Proliferation and Prognosis of Esophageal Squamous Cell Carcinoma
Demao Li, Huijie Sun, Linglei Meng & Deshang Li
Pages: 3731-3739
Published online: 20 May 2020
AbstractforRETRACTED ARTICLE: The Overexpression of Kinesin Superfamily Protein 2A (KIF2A) was Associated with the Proliferation and Prognosis of Esophageal Squamous Cell Carcinoma | PDF (5.5 MB)
  • 12 Views
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Review

Review Article
Mini-Review: Cabozantinib in the Treatment of Advanced Renal Cell Carcinoma and Hepatocellular Carcinoma
Nityam Rathi, Benjamin L Maughan, Neeraj Agarwal & Umang Swami
Pages: 3741-3749
Published online: 20 May 2020
AbstractforMini-Review: Cabozantinib in the Treatment of Advanced Renal Cell Carcinoma and Hepatocellular Carcinoma | Full Text | References | PDF (381.6 KB) | EPUB
  • 139 Views
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Original Research

Article
Validation of Risk of Chemotherapy-Induced Neutropenia: Experience from Oncology Hospital of Nepal
Binaya Sapkota, Ronash Shrestha, Safin Chapagai, Dip Kiran Shakya & Prashant Bista
Pages: 3751-3758
Published online: 20 May 2020
AbstractforValidation of Risk of Chemotherapy-Induced Neutropenia: Experience from Oncology Hospital of Nepal | Full Text | References | PDF (402.1 KB) | EPUB
  • 163 Views
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Article
CUB Domain-Containing Protein-1 Promotes Proliferation, Migration and Invasion in Cervical Cancer Cells
Lijun Huang, Yihong Chen, Shuyu Lai, Hongmei Guan, Xiaoling Hu, Jie Liu, Hanrong Zhang, Zhenfei Zhang & Jueyu Zhou
Pages: 3759-3769
Published online: 21 May 2020
AbstractforCUB Domain-Containing Protein-1 Promotes Proliferation, Migration and Invasion in Cervical Cancer Cells | Full Text | References | PDF (9.3 MB) | EPUB
  • 81 Views
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Article
Long Non-Coding RNA PART1 Promotes Proliferation, Migration and Invasion of Hepatocellular Carcinoma Cells via miR-149-5p/MAP2K1 Axis
Chao Zhou, Pu Wang, Mengtian Tu, Yi Huang, Fei Xiong & Yue Wu
Pages: 3771-3782
Published online: 21 May 2020
AbstractforLong Non-Coding RNA PART1 Promotes Proliferation, Migration and Invasion of Hepatocellular Carcinoma Cells via miR-149-5p/MAP2K1 Axis | Full Text | References | PDF (7.2 MB) | EPUB
  • 65 Views
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Article
Effects of Wnt/β-Catenin Signal Pathway Regulated by miR-342-5p Targeting CBX2 on Proliferation, Metastasis and Invasion of Ovarian Cancer Cells
Yan Dou, Fengxia Chen, Yawan Lu, Huanhuan Qiu & Hongmei Zhang
Pages: 3783-3794
Published online: 21 May 2020
AbstractforEffects of Wnt/β-Catenin Signal Pathway Regulated by miR-342-5p Targeting CBX2 on Proliferation, Metastasis and Invasion of Ovarian Cancer Cells | Full Text | References | PDF (6.9 MB) | EPUB
  • 97 Views
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Article
Curcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-β-Catenin
Xiao Zhang, Chenli Zhang, Zhiheng Ren, Fangfang Zhang, Jinyu Xu, Xu Zhang & Haixue Zheng
Pages: 3795-3806
Published online: 21 May 2020
AbstractforCurcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-β-Catenin | Full Text | References | PDF (6.1 MB) | EPUB
  • 135 Views
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Article
TOP2A Promotes Cell Migration, Invasion and Epithelial–Mesenchymal Transition in Cervical Cancer via Activating the PI3K/AKT Signaling
Bi Wang, Yaping Shen, Yin Zou, Zhengjun Qi, Guijia Huang, Shan Xia, Rui Gao, Fenghu Li & Zhi Huang
Pages: 3807-3814
Published online: 21 May 2020
AbstractforTOP2A Promotes Cell Migration, Invasion and Epithelial–Mesenchymal Transition in Cervical Cancer via Activating the PI3K/AKT Signaling | Full Text | References | PDF (4.4 MB) | EPUB
  • 133 Views
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Article
Not All Hepatocellular Carcinoma Patients with Microvascular Invasion After R0 Resection Could Be Benefited from Prophylactic Transarterial Chemoembolization: A Propensity Score Matching Study
Lei Wang, Qiao Ke, Kongying Lin, Jingbo Chen, Ren Wang, Chunhong Xiao, Xiaolong Liu & Jingfeng Liu
Pages: 3815-3825
Published online: 22 May 2020
AbstractforNot All Hepatocellular Carcinoma Patients with Microvascular Invasion After R0 Resection Could Be Benefited from Prophylactic Transarterial Chemoembolization: A Propensity Score Matching Study | Full Text | References | PDF (5.6 MB) | EPUB
  • 74 Views
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Article
A Trial of the Safety and Efficacy of Chemotherapy Plus Anlotinib vs Chemotherapy Alone as Second- or Third-Line Salvage Treatment for Advanced Non-Small Cell Lung Cancer
Hai-ying Wang, Jun-feng Chu, Yan Zhao, Hong Tang, Li-li Wang, Meng-qiang Zhou, Zheng Yan, Yan-yan Liu & Zhi-hua Yao
Pages: 3827-3834
Published online: 22 May 2020
AbstractforA Trial of the Safety and Efficacy of Chemotherapy Plus Anlotinib vs Chemotherapy Alone as Second- or Third-Line Salvage Treatment for Advanced Non-Small Cell Lung Cancer | Full Text | References | PDF (815.7 KB) | EPUB
  • 88 Views
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Article
A Nomogram for the Prognosis of Nasopharyngeal Carcinoma with MR Imaging-Detected Tumor Residue at the End of Intensity-Modulated Radiotherapy
Meng Xu, Chang Liu, Jing Lin Mi & Ren Sheng Wang
Pages: 3835-3844
Published online: 25 May 2020
AbstractforA Nomogram for the Prognosis of Nasopharyngeal Carcinoma with MR Imaging-Detected Tumor Residue at the End of Intensity-Modulated Radiotherapy | Full Text | References | PDF (2.2 MB) | EPUB
  • 69 Views
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Article
lncRNA LEF1-AS1 Promotes Proliferation and Induces Apoptosis of Non-Small-Cell Lung Cancer Cells by Regulating miR-221/PTEN Signaling
Chen Xiang, Yuanli Zhang, Yajing Zhang, Ci Liu, Yuehong Hou & Yan Zhang
Pages: 3845-3850
Published online: 25 May 2020
AbstractforlncRNA LEF1-AS1 Promotes Proliferation and Induces Apoptosis of Non-Small-Cell Lung Cancer Cells by Regulating miR-221/PTEN Signaling | Full Text | References | PDF (2.6 MB) | EPUB
  • 75 Views
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Article
Thoracoscopic Surgery to Treat Lung Metastases from Refractory Choriocarcinoma
Luo Zhao, Yingzhi Qin, Dongjie Ma, Li Li, Zhijun Han, Shanqing Li & Hongsheng Liu
Pages: 3851-3858
Published online: 25 May 2020
AbstractforThoracoscopic Surgery to Treat Lung Metastases from Refractory Choriocarcinoma | Full Text | References | PDF (1.9 MB) | EPUB
  • 60 Views
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Article
Effect of COVID-19 Epidemic on Delay of Diagnosis and Treatment Path for Patients with Nasopharyngeal Carcinoma
Youqi Yang, Chunying Shen & Chaosu Hu
Pages: 3859-3864
Published online: 25 May 2020
AbstractforEffect of COVID-19 Epidemic on Delay of Diagnosis and Treatment Path for Patients with Nasopharyngeal Carcinoma | Full Text | References | PDF (469.6 KB) | EPUB
  • 91 Views
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Article
Targeted Inhibition of CCL22 by miR-130a-5p Can Enhance the Sensitivity of Cisplatin-Resistant Gastric Cancer Cells to Chemotherapy
Qing-Liang Fang, Kai-Chun Li, Lei Wang, Xiang-Lian Gu, Ren-Jie Song & Song Lu
Pages: 3865-3875
Published online: 26 May 2020
AbstractforTargeted Inhibition of CCL22 by miR-130a-5p Can Enhance the Sensitivity of Cisplatin-Resistant Gastric Cancer Cells to Chemotherapy | Full Text | References | PDF (6.1 MB) | EPUB
  • 69 Views
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Review

Review Article
Gastrointestinal Stromal Tumors of the Small Intestine: Progress in Diagnosis and Treatment Research
Fangxing Peng & Yao Liu
Pages: 3877-3889
Published online: 25 May 2020
AbstractforGastrointestinal Stromal Tumors of the Small Intestine: Progress in Diagnosis and Treatment Research | Full Text | References | PDF (349.6 KB) | EPUB
  • 174 Views
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Review Article
Double Agent: SPDEF Gene with Both Oncogenic and Tumor-Suppressor Functions in Breast Cancer
Ting Ye, Jia Feng, Xue Wan, Dan Xie & Jinbo Liu
Pages: 3891-3902
Published online: 25 May 2020
AbstractforDouble Agent: SPDEF Gene with Both Oncogenic and Tumor-Suppressor Functions in Breast Cancer | Full Text | References | PDF (2.6 MB) | EPUB
  • 201 Views
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Original Research

Article
Long Noncoding RNA DIO3OS Hinders Cell Malignant Behaviors of Hepatocellular Carcinoma Cells Through the microRNA-328/Hhip Axis
Zhanpeng Wang, Lina Song, Yanshuo Ye & Wei Li
Pages: 3903-3914
Published online: 25 May 2020
AbstractforLong Noncoding RNA DIO3OS Hinders Cell Malignant Behaviors of Hepatocellular Carcinoma Cells Through the microRNA-328/Hhip Axis | Full Text | References | PDF (8.4 MB) | EPUB
  • 87 Views
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Article
Mechanism of the Regulatory Effect of Overexpression of circMTO1 on Proliferation and Apoptosis of Hepatoma Cells via miR-9-5p/NOX4 Axis
Jinbao Wang, Qingjuan Tan, Weishan Wang & Jie Yu
Pages: 3915-3925
Published online: 26 May 2020
AbstractforMechanism of the Regulatory Effect of Overexpression of circMTO1 on Proliferation and Apoptosis of Hepatoma Cells via miR-9-5p/NOX4 Axis | Full Text | References | PDF (7.7 MB) | EPUB
  • 76 Views
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Article
hsa_circ_0008285 Facilitates the Progression of Cervical Cancer by Targeting miR-211-5p/SOX4 Axis
Youpeng Bai & Xicong Li
Pages: 3927-3936
Published online: 26 May 2020
Abstractforhsa_circ_0008285 Facilitates the Progression of Cervical Cancer by Targeting miR-211-5p/SOX4 Axis | Full Text | References | PDF (7.2 MB) | EPUB
  • 75 Views
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Article
A Predictive Scoring System Based on Inflammatory and Tumor Markers for Gastric Cancer Patients Undergoing Curative Resection
Li-Wen Feng, Jing Li, Li-Feng Liang, Qian-Qian Guo, Jiang Li, Jian Wu, Pei-Hua Zhang & Yan-Ru Qin
Pages: 3937-3948
Published online: 26 May 2020
AbstractforA Predictive Scoring System Based on Inflammatory and Tumor Markers for Gastric Cancer Patients Undergoing Curative Resection | Full Text | References | PDF (4.2 MB) | EPUB
  • 76 Views
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Article
Long Non-Coding RNA SLC25A21-AS1 Promotes Multidrug Resistance in Nasopharyngeal Carcinoma by Regulating miR-324-3p/IL-6 Axis
Xiaoqin Wang, Chunhui Wang, Hong Xu & Hong Xie
Pages: 3949-3957
Published online: 26 May 2020
AbstractforLong Non-Coding RNA SLC25A21-AS1 Promotes Multidrug Resistance in Nasopharyngeal Carcinoma by Regulating miR-324-3p/IL-6 Axis | Full Text | References | PDF (6.6 MB) | EPUB
  • 77 Views
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Article
Risk Factors and Patterns of Abdominal Lymph Node Recurrence After Radical Surgery for Locally Advanced Thoracic Esophageal Squamous Cell Cancer
Yichun Wang, Dongmei Ye, Mei Kang, Liyang Zhu, Shuhao Pan & Fan Wang
Pages: 3959-3969
Published online: 27 May 2020
AbstractforRisk Factors and Patterns of Abdominal Lymph Node Recurrence After Radical Surgery for Locally Advanced Thoracic Esophageal Squamous Cell Cancer | Full Text | References | PDF (6.3 MB) | EPUB
  • 63 Views
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Article
LINC02381 Promoted Cell Viability and Migration via Targeting miR-133b in Cervical Cancer Cells
Xiaohua Chen, Zhuxiang Zhang, Yan Ma, Hongxin Su, Peng Xie & Juntao Ran
Pages: 3971-3979
Published online: 26 May 2020
AbstractforLINC02381 Promoted Cell Viability and Migration via Targeting miR-133b in Cervical Cancer Cells | Full Text | References | PDF (4.9 MB) | EPUB
  • 89 Views
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Article
KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway
Yi Song, Huiping Yuan, Jia Wang, Yuhe Wu, Yuhong Xiao & Shengxun Mao
Pages: 3981-3993
Published online: 27 May 2020
AbstractforKLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway | Full Text | References | PDF (8.3 MB) | EPUB
  • 69 Views
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Article
A Nomogram Based on Preoperative Clinical Bio-Indicators to Predict 5-year Survivals for Patients with Gastric Cancer After Radical Gastrectomy
Qi Hang Yin, Bin Zheng Liu, Meng Qing Xu, Lin Tao, Kui Wang, Feng Li & Wen Jie Zhang
Pages: 3995-4007
Published online: 27 May 2020
AbstractforA Nomogram Based on Preoperative Clinical Bio-Indicators to Predict 5-year Survivals for Patients with Gastric Cancer After Radical Gastrectomy | Full Text | References | PDF (2 MB) | EPUB
  • 67 Views
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Article
Germacrone Induces Apoptosis as Well as Protective Autophagy in Human Prostate Cancer Cells
Ziqiang Yu, Jiuping Xu, Mingfeng Shao & Jianan Zou
Pages: 4009-4016
Published online: 27 May 2020
AbstractforGermacrone Induces Apoptosis as Well as Protective Autophagy in Human Prostate Cancer Cells | Full Text | References | PDF (5.5 MB) | EPUB
  • 93 Views
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Article
Construction of a 13-Gene Signature as a Novel Prognostic Marker for Patients with Clear Cell Renal Cell Carcinoma and the Role of XCR1 in Cell Proliferation
Baoying Yuan, Feifei Li, Youbao Li & Yuhan Chen
Pages: 4017-4027
Published online: 27 May 2020
AbstractforConstruction of a 13-Gene Signature as a Novel Prognostic Marker for Patients with Clear Cell Renal Cell Carcinoma and the Role of XCR1 in Cell Proliferation | Full Text | References | PDF (7.2 MB) | EPUB
  • 74 Views
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Article
Assessment of Nine Driver Gene Mutations in Surgically Resected Samples from Patients with Non-Small-Cell Lung Cancer
Shuo Wang, Xiujuan Qu, Lili Cao, Xuejun Hu, Kezuo Hou, Yunpeng Liu & Xiaofang Che
Pages: 4029-4038
Published online: 28 May 2020
AbstractforAssessment of Nine Driver Gene Mutations in Surgically Resected Samples from Patients with Non-Small-Cell Lung Cancer | Full Text | References | PDF (6.3 MB) | EPUB
  • 69 Views
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Article
SOX10 – A Novel Marker for the Differential Diagnosis of Breast Metaplastic Squamous Cell Carcinoma
Jialin Qi, Zhenmin Hu, Heng Xiao, Ruijie Liu, Wei Guo, Zhichun Yang, Kewen Ma, Shitong Su, Ping Tang, Xunjian Zhou, Jianhua Zhou & Kuansong Wang
Pages: 4039-4044
Published online: 28 May 2020
AbstractforSOX10 – A Novel Marker for the Differential Diagnosis of Breast Metaplastic Squamous Cell Carcinoma | Full Text | References | PDF (618.8 KB) | EPUB
  • 111 Views
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Article
Upregulation of hsa_circRNA_102958 Indicates Poor Prognosis and Promotes Ovarian Cancer Progression Through miR-1205/SH2D3A Axis
Guan Wang, Huijing Zhang & Peiling Li
Pages: 4045-4053
Published online: 28 May 2020
AbstractforUpregulation of hsa_circRNA_102958 Indicates Poor Prognosis and Promotes Ovarian Cancer Progression Through miR-1205/SH2D3A Axis | Full Text | References | PDF (6.6 MB) | EPUB
  • 84 Views
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Article
Endoscopic Submucosal Dissection of Gastrointestinal Stromal Tumours: A Retrospective Cohort Study
Ruonan Jiao, Si Zhao, Wei Jiang, Xin Wei & Guangming Huang
Pages: 4055-4061
Published online: 29 May 2020
AbstractforEndoscopic Submucosal Dissection of Gastrointestinal Stromal Tumours: A Retrospective Cohort Study | Full Text | References | PDF (286.6 KB) | EPUB
  • 78 Views
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Article
Postoperative Concurrent Chemoradiotherapy versus Postoperative Radiotherapy Alone for Larynx Squamous Cell Carcinoma Patients with Lymphovascular Invasion: A Propensity Score Matching Study
Shuting Yu, Yingying Zhu, Xiaohua Shi, Ke Hu, Chunmei Bai, Wenwen Diao, Xiaoli Zhu, Zhiqiang Gao & Xingming Chen
Pages: 4063-4071
Published online: 29 May 2020
AbstractforPostoperative Concurrent Chemoradiotherapy versus Postoperative Radiotherapy Alone for Larynx Squamous Cell Carcinoma Patients with Lymphovascular Invasion: A Propensity Score Matching Study | Full Text | References | PDF (1.9 MB) | EPUB
  • 73 Views
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Article
LncRNA DANCR-miR-758-3p-PAX6 Molecular Network Regulates Apoptosis and Autophagy of Breast Cancer Cells
Xian Hu Zhang, Bing Feng Li, Jie Ding, Lei Shi, Huo Ming Ren, Kui Liu, Chuan Cai Huang, Fu Xiao Ma & Xin Yao Wu
Pages: 4073-4084
Published online: 29 May 2020
AbstractforLncRNA DANCR-miR-758-3p-PAX6 Molecular Network Regulates Apoptosis and Autophagy of Breast Cancer Cells | Full Text | References | PDF (8.5 MB) | EPUB
  • 85 Views
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Article
Expression Analysis of GRHL3 and PHLDA3 in Head and Neck Squamous Cell Carcinoma
Negin Saffarzadeh, Soudeh Ghafouri-Fard, Zahra Rezaei, Keyvan Aghazadeh, Farzad Yazdani, Mehdi Mohebi, Mohsen Ahmadi, Abbas Shakoori & Javad Tavakkoly-Bazzaz
Pages: 4085-4096
Published online: 02 Jun 2020
AbstractforExpression Analysis of GRHL3 and PHLDA3 in Head and Neck Squamous Cell Carcinoma | Full Text | References | PDF (5.3 MB) | EPUB
  • 77 Views
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Article
The Value of TTPVI in Prediction of Microvascular Invasion in Hepatocellular Carcinoma
Tao Zhang, Gaurab Pandey, Lin Xu, Wen Chen, Liangrui Gu, Yijun Wu & Xiuwen Chen
Pages: 4097-4105
Published online: 02 Jun 2020
AbstractforThe Value of TTPVI in Prediction of Microvascular Invasion in Hepatocellular Carcinoma | Full Text | References | PDF (1.1 MB) | EPUB
  • 76 Views
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Article
Factors Predicting Severe Myelosuppression and Its Influence on Fertility in Patients with Low-Risk Gestational Trophoblastic Neoplasia Receiving Single-Agent Methotrexate Chemotherapy
Xiaoyu Tu, Ruizhe Chen, Genping Huang, Nanjia Lu, Qin Chen, Xiaoxia Bai & Baohua Li
Pages: 4107-4116
Published online: 02 Jun 2020
AbstractforFactors Predicting Severe Myelosuppression and Its Influence on Fertility in Patients with Low-Risk Gestational Trophoblastic Neoplasia Receiving Single-Agent Methotrexate Chemotherapy | Full Text | References | PDF (1.5 MB) | EPUB
  • 67 Views
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Review

Review Article
Clinical Implications of the Associations Between Intestinal Microbiome and Colorectal Cancer Progression
Yongkang Chen, Yong Yang & Jin Gu
Pages: 4117-4128
Published online: 09 Jun 2020
AbstractforClinical Implications of the Associations Between Intestinal Microbiome and Colorectal Cancer Progression | Full Text | References | PDF (435.7 KB) | EPUB
  • 126 Views
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Original Research

Article
miR-100-5p Inhibits Malignant Behavior of Chordoma Cells by Targeting IGF1R
Hongliang Zhang, Kang Yang, Tingting Ren, Yi Huang, Xin Liang, Yiyang Yu, Wei Wang, Jianfang Niu, Jingbing Lou, Xiaodong Tang & Wei Guo
Pages: 4129-4137
Published online: 02 Jun 2020
AbstractformiR-100-5p Inhibits Malignant Behavior of Chordoma Cells by Targeting IGF1R | Full Text | References | PDF (7.3 MB) | EPUB
  • 69 Views
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Article
Identification of Patients with Brain Metastases with Favorable Prognosis After Local and Distant Recurrence Following Stereotactic Radiosurgery
Xuechao Jiang
Pages: 4139-4149
Published online: 03 Jun 2020
AbstractforIdentification of Patients with Brain Metastases with Favorable Prognosis After Local and Distant Recurrence Following Stereotactic Radiosurgery | Full Text | References | PDF (2.4 MB) | EPUB
  • 55 Views
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Article
Glucose Transporter-1 Cooperating with AKT Signaling Promote Gastric Cancer Progression
Diyuan Zhou, Linhua Jiang, Lichen Jin, Yizhou Yao, Peijie Wang & Xinguo Zhu
Pages: 4151-4160
Published online: 03 Jun 2020
AbstractforGlucose Transporter-1 Cooperating with AKT Signaling Promote Gastric Cancer Progression | Full Text | References | PDF (5.6 MB) | EPUB
  • 83 Views
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Article
Efficacy of Nivolumab for Head and Neck Cancer Patients with Primary Sites and Histological Subtypes Excluded from the CheckMate-141 Trial
Yasuyoshi Sato, Naoki Fukuda, Xiaofei Wang, Tetsuya Urasaki, Akihiro Ohmoto, Kenji Nakano, Mayu Yunokawa, Makiko Ono, Yukiko Sato, Hiroki Mitani, Junichi Tomomatsu & Shunji Takahashi
Pages: 4161-4168
Published online: 03 Jun 2020
AbstractforEfficacy of Nivolumab for Head and Neck Cancer Patients with Primary Sites and Histological Subtypes Excluded from the CheckMate-141 Trial | Full Text | References | PDF (3.4 MB) | EPUB
  • 113 Views
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Corrigendum

Correction
Drug-Related Hypertension Associated with the Efficacy of Apatinib on Hepatocellular Carcinoma [Corrigendum]
Pages: 4169-4170
Published online: 03 Jun 2020
CitationforDrug-Related Hypertension Associated with the Efficacy of Apatinib on Hepatocellular Carcinoma [Corrigendum] | Full Text | PDF (1.6 MB) | EPUB
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Original Research

Article
RETRACTED ARTICLE: MiR-625 Inhibits Tumor Cell Invasion, Migration and EMT by Negatively Regulating the Expression of Resistin in Non-Small Cell Lung
Yongsheng Zhao, Renyan Zheng, Dong Ning & Fei Xie
Pages: 4171-4180
Published online: 03 Jun 2020
AbstractforRETRACTED ARTICLE: MiR-625 Inhibits Tumor Cell Invasion, Migration and EMT by Negatively Regulating the Expression of Resistin in Non-Small Cell Lung | PDF (3.4 MB)
  • 57 Views
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Review

Review Article
Roles of Wnt/β-Catenin Signaling Pathway Regulatory Long Non-Coding RNAs in the Pathogenesis of Non-Small Cell Lung Cancer
Shan Lin, Yu Zhen, Yinghui Guan & Huanfa Yi
Pages: 4181-4191
Published online: 03 Jun 2020
AbstractforRoles of Wnt/β-Catenin Signaling Pathway Regulatory Long Non-Coding RNAs in the Pathogenesis of Non-Small Cell Lung Cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 101 Views
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Original Research

Article
CONUT Score or/and Peripheral Blood CD4+/CD8+ Ratio-Based Web Dynamic Nomograms to Predict the Individualized Survival of Patients with Advanced Osteosarcoma
Qian-Kun Yang, Yan-Na Su, Wei Wang, Nan Wang, Zhong-Xiang Yao & Xiao-Jing Zhang
Pages: 4193-4208
Published online: 03 Jun 2020
AbstractforCONUT Score or/and Peripheral Blood CD4+/CD8+ Ratio-Based Web Dynamic Nomograms to Predict the Individualized Survival of Patients with Advanced Osteosarcoma | Full Text | References | PDF (6.2 MB) | EPUB
  • 91 Views
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Article
LncRNA MAGI2-AS3 Affects Cell Invasion and Migration of Cervical Squamous Cell Carcinoma (CSCC) via Sponging miRNA-233/EPB41L3 Axis
Anli Hou, Yali Zhang, Yujuan Fan, Yi Zheng, Xiuying Zhou & Huilan Liu
Pages: 4209-4216
Published online: 03 Jun 2020
AbstractforLncRNA MAGI2-AS3 Affects Cell Invasion and Migration of Cervical Squamous Cell Carcinoma (CSCC) via Sponging miRNA-233/EPB41L3 Axis | Full Text | References | PDF (6.4 MB) | EPUB
  • 75 Views
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Article
Clinicopathological Characteristics and Prognostic Factors of Patients with Gastric Cancer Accompanying Neuroendocrine Differentiation (NEDGC)
Ya-Ping Wang, Jun Hong, Jian Wang, Yi-Bing Bei, Han-Kun Hao & Lu-Chun Hua
Pages: 4217-4225
Published online: 03 Jun 2020
AbstractforClinicopathological Characteristics and Prognostic Factors of Patients with Gastric Cancer Accompanying Neuroendocrine Differentiation (NEDGC) | Full Text | References | PDF (3.9 MB) | EPUB
  • 69 Views
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Article
LncRNA LINC00689 Promotes the Progression of Gastric Cancer Through Upregulation of ADAM9 by Sponging miR-526b-3p
Gang Yin, PeiRong Tian, Amin BuHe, Wei Yan, TianXiong Li & ZhiPeng Sun
Pages: 4227-4239
Published online: 04 Jun 2020
AbstractforLncRNA LINC00689 Promotes the Progression of Gastric Cancer Through Upregulation of ADAM9 by Sponging miR-526b-3p | Full Text | References | PDF (4.7 MB) | EPUB
  • 70 Views
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Article
Efficacy and Safety of Cyclin-Dependent Kinases 4 and 6 Inhibitors in HR+/HER2− Advanced Breast Cancer
Ning Xie, Tao Qin, Wei Ren, Herui Yao, Yunfang Yu & Huangming Hong
Pages: 4241-4250
Published online: 04 Jun 2020
AbstractforEfficacy and Safety of Cyclin-Dependent Kinases 4 and 6 Inhibitors in HR+/HER2− Advanced Breast Cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 83 Views
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Corrigendum

Correction
CIRP Regulates BEV-Induced Cell Migration in Gliomas [Corrigendum]
Pages: 4251-4252
Published online: 08 Jun 2020
CitationforCIRP Regulates BEV-Induced Cell Migration in Gliomas [Corrigendum] | Full Text | PDF (2.3 MB) | EPUB
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Review

Review Article
The Clinical Diagnostic and Prognostic Value of Dickkopf-1 in Cancer
Jie Li, Yan Gao & Wentao Yue
Pages: 4253-4260
Published online: 08 Jun 2020
AbstractforThe Clinical Diagnostic and Prognostic Value of Dickkopf-1 in Cancer | Full Text | References | PDF (327.1 KB) | EPUB
  • 98 Views
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Original Research

Article
CFTR Functions as a Tumor Suppressor and Is Regulated by DNA Methylation in Colorectal Cancer
Can Liu, Chao Song, Jiaxi Li & Qing Sun
Pages: 4261-4270
Published online: 08 Jun 2020
AbstractforCFTR Functions as a Tumor Suppressor and Is Regulated by DNA Methylation in Colorectal Cancer | Full Text | References | PDF (3 MB) | EPUB
  • 144 Views
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Article
Functions and Clinical Significance of UPF3a Expression in Human Colorectal Cancer
Xinmin Bao, Yuji Huang, Weimin Xu & Gongyou Xiong
Pages: 4271-4281
Published online: 08 Jun 2020
AbstractforFunctions and Clinical Significance of UPF3a Expression in Human Colorectal Cancer | Full Text | References | PDF (5.7 MB) | EPUB
  • 70 Views
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Article
Exosomal Transfer of lncRNA H19 Promotes Erlotinib Resistance in Non-Small Cell Lung Cancer via miR-615-3p/ATG7 Axis
Rongtao Pan & Haiyan Zhou
Pages: 4283-4297
Published online: 08 Jun 2020
AbstractforExosomal Transfer of lncRNA H19 Promotes Erlotinib Resistance in Non-Small Cell Lung Cancer via miR-615-3p/ATG7 Axis | Full Text | References | PDF (11.6 MB) | EPUB
  • 86 Views
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Article
Intercalary Allograft to Reconstruct Large-Segment Diaphysis Defects After Resection of Lower Extremity Malignant Bone Tumor
Qing Liu, Hongbo He, Zhixi Duan, Hao Zeng, Yuhao Yuan, Zhiwei Wang & Wei Luo
Pages: 4299-4308
Published online: 08 Jun 2020
AbstractforIntercalary Allograft to Reconstruct Large-Segment Diaphysis Defects After Resection of Lower Extremity Malignant Bone Tumor | Full Text | References | PDF (3.8 MB) | EPUB
  • 116 Views
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Article
MiR-301a Promotes Cell Proliferation by Repressing PTEN in Renal Cell Carcinoma
Jun Li, Donggen Jiang, Qian Zhang, Shubin Peng, Guolong Liao, Xiangwei Yang, Jiani Tang, Haiyun Xiong & Jun Pang
Pages: 4309-4320
Published online: 10 Jun 2020
AbstractforMiR-301a Promotes Cell Proliferation by Repressing PTEN in Renal Cell Carcinoma | Full Text | References | PDF (8.7 MB) | EPUB
  • 83 Views
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Article
RETRACTED ARTICLE: Hypoxia-Induced Aquaporin-3 Changes Hepatocellular Carcinoma Cell Sensitivity to Sorafenib by Activating the PI3K/Akt Signaling Pathway
Kija Malale, Jili Fu, Liewang Qiu, Ke Zhan, Xiuni Gan & Zhechuan Mei
Pages: 4321-4333
Published online: 09 Jun 2020
AbstractforRETRACTED ARTICLE: Hypoxia-Induced Aquaporin-3 Changes Hepatocellular Carcinoma Cell Sensitivity to Sorafenib by Activating the PI3K/Akt Signaling Pathway | PDF (8.7 MB)
  • 19 Views
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Article
MicroRNA-379-5p/YBX1 Axis Regulates Cellular EMT to Suppress Migration and Invasion of Nasopharyngeal Carcinoma Cells
Fei Zhang, Chuanxin Duan, Shucheng Yin & Ying Tian
Pages: 4335-4346
Published online: 09 Jun 2020
AbstractforMicroRNA-379-5p/YBX1 Axis Regulates Cellular EMT to Suppress Migration and Invasion of Nasopharyngeal Carcinoma Cells | Full Text | References | PDF (7.1 MB) | EPUB
  • 72 Views
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Article
LncRNA DSCAM-AS1 Promotes Colon Cancer Cells Proliferation and Migration via Regulating the miR-204/SOX4 Axis
Canrong Lu, Tianyu Xie, Xin Guo, Di Wu, Shuo Li, Xiongguang Li, Yixun Lu & Xinxin Wang
Pages: 4347-4356
Published online: 09 Jun 2020
AbstractforLncRNA DSCAM-AS1 Promotes Colon Cancer Cells Proliferation and Migration via Regulating the miR-204/SOX4 Axis | Full Text | References | PDF (5.2 MB) | EPUB
  • 68 Views
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Review

Review Article
A Systematic Review of Health Economic Evaluation on Targeted Therapies for First-Line Treatment of Metastatic Non-Small Cell Lung Cancer (NSCLC): Quality Evaluation
Jie Zhao, Shuzhang Du, Yumei Zhu, Yan Liang, Jingli Lu & Feng Chang
Pages: 4357-4368
Published online: 09 Jun 2020
AbstractforA Systematic Review of Health Economic Evaluation on Targeted Therapies for First-Line Treatment of Metastatic Non-Small Cell Lung Cancer (NSCLC): Quality Evaluation | Full Text | References | PDF (492.2 KB) | EPUB
  • 127 Views
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Original Research

Article
Efficacy and Safety of Androgen-Deprivation Therapy Combined with Docetaxel Plus Prednisone in High-Burden Metastatic Hormone-Sensitive Prostate Cancer
Linjun Hu, Qinxin Zhao, Hongsong Bai, Chengming Xie, Xingli Shan, Dehu Lu, Yonghai Chen, Dongdong Han, Zejun Xiao, Jun Tian, Dong Wang, Xingang Bi & Nianzeng Xing
Pages: 4369-4377
Published online: 09 Jun 2020
AbstractforEfficacy and Safety of Androgen-Deprivation Therapy Combined with Docetaxel Plus Prednisone in High-Burden Metastatic Hormone-Sensitive Prostate Cancer | Full Text | References | PDF (2.7 MB) | EPUB
  • 65 Views
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Article
RETRACTED ARTICLE: LncRNA HOTAIRM1 Inhibits the Proliferation and Invasion of Lung Adenocarcinoma Cells via the miR-498/WWOX Axis
Tian-jun Chen, Fei Gao, Tian Yang, Hong Li, Yang Li, Hui Ren & Ming-wei Chen
Pages: 4379-4390
Published online: 09 Jun 2020
AbstractforRETRACTED ARTICLE: LncRNA HOTAIRM1 Inhibits the Proliferation and Invasion of Lung Adenocarcinoma Cells via the miR-498/WWOX Axis | PDF (10.4 MB)
  • 65 Views
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Article
Risk Factors for Postoperative Infectious Complications in Elderly Patients with Gastric Cancer
Xiao Liu, Zhigang Xue, Jianchun Yu, Zijian Li, Zhiqiang Ma, Weiming Kang, Xin Ye & Lin Jiang
Pages: 4391-4398
Published online: 09 Jun 2020
AbstractforRisk Factors for Postoperative Infectious Complications in Elderly Patients with Gastric Cancer | Full Text | References | PDF (5 MB) | EPUB
  • 105 Views
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Article
Comprehensive Analysis of PD-1 Gene Expression, Immune Characteristics and Prognostic Significance in 1396 Glioma Patients
Chaojun Liu, Zhen Zhang, Yu Ping, Guohui Qin, Kai Zhang, Nomathamsanqa Resegofetse Maimela, Lan Huang, Shengli Yang & Yi Zhang
Pages: 4399-4410
Published online: 10 Jun 2020
AbstractforComprehensive Analysis of PD-1 Gene Expression, Immune Characteristics and Prognostic Significance in 1396 Glioma Patients | Full Text | References | PDF (9.9 MB) | EPUB
  • 72 Views
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Article
ELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells
Zhi Wang, Laura E Pascal, Uma R Chandran, Srilakshmi Chaparala, Shidong Lv, Hui Ding, Lin Qi & Zhou Wang
Pages: 4411-4427
Published online: 10 Jun 2020
AbstractforELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells | Full Text | References | PDF (13 MB) | EPUB
  • 95 Views
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Article
Combination BET Family Protein and HDAC Inhibition Synergistically Elicits Chondrosarcoma Cell Apoptosis Through RAD51-Related DNA Damage Repair
Songwei Huan, Tao Gui, Qiutong Xu, Songkuan Zhuang, Zhenyan Li, Yuling Shi, Jiebin Lin, Bin Gong, Guiqiang Miao, Manseng Tam, Huan-Tian Zhang, Zhengang Zha & Chunfei Wu
Pages: 4429-4439
Published online: 10 Jun 2020
AbstractforCombination BET Family Protein and HDAC Inhibition Synergistically Elicits Chondrosarcoma Cell Apoptosis Through RAD51-Related DNA Damage Repair | Full Text | References | PDF (7.4 MB) | EPUB
  • 89 Views
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Article
Five Serum Trace Elements Associated with Risk of Cardia and Noncardia Gastric Cancer in a Matched Case–Control Study
Yulan Lin, Chuancheng Wu, Wei Yan, Saixiong Guo & Baoying Liu
Pages: 4441-4451
Published online: 10 Jun 2020
AbstractforFive Serum Trace Elements Associated with Risk of Cardia and Noncardia Gastric Cancer in a Matched Case–Control Study | Full Text | References | PDF (391.6 KB) | EPUB
  • 156 Views
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Article
Inhibition of lncRNA PART1 Chemosensitizes Wild Type but Not KRAS Mutant NSCLC Cells
Shu-Chen Chen, Yu-Zhu Diao, Zi-Han Zhao & Xiao-Ling Li
Pages: 4453-4460
Published online: 10 Jun 2020
AbstractforInhibition of lncRNA PART1 Chemosensitizes Wild Type but Not KRAS Mutant NSCLC Cells | Full Text | References | PDF (4.7 MB) | EPUB
  • 68 Views
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Article
Development and Validation of a Nomogram Predicting the Prognosis of Renal Cell Carcinoma After Nephrectomy
Mancheng Xia, Haosen Yang, Yusheng Wang, Keqiang Yin, Xiaodong Bian, Jiawei Chen & Weibing Shuang
Pages: 4461-4473
Published online: 11 Jun 2020
AbstractforDevelopment and Validation of a Nomogram Predicting the Prognosis of Renal Cell Carcinoma After Nephrectomy | Full Text | References | PDF (725.9 KB) | EPUB
  • 70 Views
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Article
Combination of CA19-9 and the Neutrophil-to-Lymphocyte Ratio for the Differential Diagnosis of Gallbladder Carcinoma
Zeyang Chen, Zining Liu, Yuyang Zhang, Pengyuan Wang & Hongqiao Gao
Pages: 4475-4482
Published online: 12 Jun 2020
AbstractforCombination of CA19-9 and the Neutrophil-to-Lymphocyte Ratio for the Differential Diagnosis of Gallbladder Carcinoma | Full Text | References | PDF (2 MB) | EPUB
  • 70 Views
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Article
Perioperative Complications and Safety Evaluation of Robot-Assisted Radical Hysterectomy of Cervical Cancer After Neoadjuvant Chemotherapy
Wei-Fu Chang, Ai-Jing Luo, Yi-Feng Yuan, Yang Chen, Zi-Rui Xin & Shuai-Shuai Xu
Pages: 4483-4492
Published online: 12 Jun 2020
AbstractforPerioperative Complications and Safety Evaluation of Robot-Assisted Radical Hysterectomy of Cervical Cancer After Neoadjuvant Chemotherapy | Full Text | References | PDF (283.1 KB) | EPUB
  • 78 Views
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Article
Impact of Ovarian Metastatectomy on Survival Outcome of Colorectal Cancer Patients with Ovarian Metastasis: A Retrospective Study
Xiaofen Li, Hai Huang, Longyao Ran, Chao Fang, Yongyang Yu, Manxi Luo & Meng Qiu
Pages: 4493-4501
Published online: 12 Jun 2020
AbstractforImpact of Ovarian Metastatectomy on Survival Outcome of Colorectal Cancer Patients with Ovarian Metastasis: A Retrospective Study | Full Text | References | PDF (1.1 MB) | EPUB
  • 148 Views
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Review

Review Article
Economic Evaluations of Immune Checkpoint Inhibitors for Patients with Non-Small Cell Lung Cancer: A Systematic Review
Na Li, Huanrui Zheng, Bin Zheng, Chaoxin Chen, Hongfu Cai & Maobai Liu
Pages: 4503-4518
Published online: 12 Jun 2020
AbstractforEconomic Evaluations of Immune Checkpoint Inhibitors for Patients with Non-Small Cell Lung Cancer: A Systematic Review | Full Text | References | PDF (1.4 MB) | EPUB
  • 91 Views
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Original Research

Article
Mitochondrial Stress–Mediated Targeting of Quiescent Cancer Stem Cells in Oral Squamous Cell Carcinoma
Tajindra Singh Saluja, Vijay Kumar, Monika Agrawal, Abhilasha Tripathi, Rajesh Kumar Meher, Kamini Srivastava, Anurag Gupta, Anjana Singh, Arun Chaturvedi & Satyendra Kumar Singh
Pages: 4519-4530
Published online: 15 Jun 2020
AbstractforMitochondrial Stress–Mediated Targeting of Quiescent Cancer Stem Cells in Oral Squamous Cell Carcinoma | Full Text | References | PDF (9 MB) | EPUB
  • 128 Views
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Article
LncRNA TDRG1 Promotes Proliferation, Invasion and Epithelial-Mesenchymal Transformation of Osteosarcoma Through PI3K/AKT Signal Pathway
Yan Huang, Yong-Qiang Xu, Si-Yin Feng, Xiang Zhang & Jiang-Dong Ni
Pages: 4531-4540
Published online: 15 Jun 2020
AbstractforLncRNA TDRG1 Promotes Proliferation, Invasion and Epithelial-Mesenchymal Transformation of Osteosarcoma Through PI3K/AKT Signal Pathway | Full Text | References | PDF (5.5 MB) | EPUB
  • 61 Views
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Article
RETRACTED ARTICLE: Cell Differentiation Agent-2 (CDA-2) Inhibits the Growth and Migration of Saos-2 Cells via miR-124/MAPK1
Quanxiu Li, Guangchun Li, Changyi Liu, Na Chen, Bangyu Deng & Youke Xie
Pages: 4541-4548
Published online: 15 Jun 2020
AbstractforRETRACTED ARTICLE: Cell Differentiation Agent-2 (CDA-2) Inhibits the Growth and Migration of Saos-2 Cells via miR-124/MAPK1 | PDF (5 MB)
  • 18 Views
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Article
Prospective Study of the Clinical Impact of Epithelial and Mesenchymal Circulating Tumor Cells in Localized Prostate Cancer
Hailong Liu, Jie Ding, Yanyuan Wu, Di Wu & Jun Qi
Pages: 4549-4560
Published online: 15 Jun 2020
AbstractforProspective Study of the Clinical Impact of Epithelial and Mesenchymal Circulating Tumor Cells in Localized Prostate Cancer | Full Text | References | PDF (4.5 MB) | EPUB
  • 70 Views
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Article
Effect of LINC00657 on Apoptosis of Breast Cancer Cells by Regulating miR-590-3p
Qiuli Shan, Fan Qu, Weiping Yang & Ningning Chen
Pages: 4561-4571
Published online: 15 Jun 2020
AbstractforEffect of LINC00657 on Apoptosis of Breast Cancer Cells by Regulating miR-590-3p | Full Text | References | PDF (6.8 MB) | EPUB
  • 67 Views
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Article
Localization of Nuclei in Breast Cancer Using Whole Slide Imaging System Supported by Morphological Features and Shape Formulas
Anil Kumar & Manish Prateek
Pages: 4573-4583
Published online: 16 Jun 2020
AbstractforLocalization of Nuclei in Breast Cancer Using Whole Slide Imaging System Supported by Morphological Features and Shape Formulas | Full Text | References | PDF (6.3 MB) | EPUB
  • 129 Views
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Article
Multiple Immune-Related Adverse Events and Anti-Tumor Efficacy: Real-World Data on Various Solid Tumors
Keitaro Shimozaki, Yasutaka Sukawa, Noriko Beppu, Isao Kurihara, Shigeaki Suzuki, Ryuichi Mizuno, Takeru Funakoshi, Shinnosuke Ikemura, Kai Tsugaru, Kazuhiro Togasaki, Kenta Kawasaki, Kenro Hirata, Hideyuki Hayashi, Yasuo Hamamoto, Hiromasa Takaishi & Takanori Kanai
Pages: 4585-4593
Published online: 16 Jun 2020
AbstractforMultiple Immune-Related Adverse Events and Anti-Tumor Efficacy: Real-World Data on Various Solid Tumors | Full Text | References | PDF (3.8 MB) | EPUB
  • 151 Views
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Review

Review Article
Regulation of Autophagy by Non-Steroidal Anti-Inflammatory Drugs in Cancer
Xiangjie Fu, Tan Tan & Peijun Liu
Pages: 4595-4604
Published online: 16 Jun 2020
AbstractforRegulation of Autophagy by Non-Steroidal Anti-Inflammatory Drugs in Cancer | Full Text | References | PDF (2.3 MB) | EPUB
  • 158 Views
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Original Research

Article
RETRACTED ARTICLE: Silencing of lncRNA LINC00346 Inhibits the Proliferation and Promotes the Apoptosis of Colorectal Cancer Cells Through Inhibiting JAK1/STAT3 Signaling
Dan Li & Shuang Wen
Pages: 4605-4614
Published online: 16 Jun 2020
AbstractforRETRACTED ARTICLE: Silencing of lncRNA LINC00346 Inhibits the Proliferation and Promotes the Apoptosis of Colorectal Cancer Cells Through Inhibiting JAK1/STAT3 Signaling | PDF (6.8 MB)
  • 10 Views
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Article
Spatial Variation in Lung Cancer Mortality and Related Men–Women Disparities in Iran from 2011 to 2014
Shadi Ghasemi, Behzad Mahaki, Emanuela Dreassi & Saeedeh Aghamohammadi
Pages: 4615-4624
Published online: 17 Jun 2020
AbstractforSpatial Variation in Lung Cancer Mortality and Related Men–Women Disparities in Iran from 2011 to 2014 | Full Text | References | PDF (2.6 MB) | EPUB
  • 96 Views
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Article
CD56 Expression Is Associated with Biological Behavior of Pancreatic Neuroendocrine Neoplasms
Xin Chen, Chuangen Guo, Wenjing Cui, Ke Sun, Zhongqiu Wang & Xiao Chen
Pages: 4625-4631
Published online: 17 Jun 2020
AbstractforCD56 Expression Is Associated with Biological Behavior of Pancreatic Neuroendocrine Neoplasms | Full Text | References | PDF (1.3 MB) | EPUB
  • 79 Views
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Study Protocol

Brief Report
Icotinib as Adjuvant Treatment for Stage II-IIIA Lung Adenocarcinoma Patients with EGFR Mutation (ICWIP Study): Study Protocol for a Randomised Controlled Trial
Yu-Tao Liu, Xue-Zhi Hao, De-Ruo Liu, Gang Cheng, Shu-Cai Zhang, Wen-Hua Xiao, Yi Hu, Jun-Feng Liu, Ming He, Cui-Min Ding, Li Zhang, Jun Wang, Hui Li, Gui-Lan Dong, Xiu-Yi Zhi, Jian Li & Yuan-Kai Shi
Pages: 4633-4643
Published online: 17 Jun 2020
AbstractforIcotinib as Adjuvant Treatment for Stage II-IIIA Lung Adenocarcinoma Patients with EGFR Mutation (ICWIP Study): Study Protocol for a Randomised Controlled Trial | Full Text | References | PDF (2.6 MB) | EPUB
  • 114 Views
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Original Research

Article
Synergistic Anticancer Effects of Gemcitabine with Pitavastatin on Pancreatic Cancer Cell Line MIA PaCa-2 in vitro and in vivo
Ya-Hui Chen, Yi-Chun Chen, Chi-Chen Lin, Yao-Peng Hsieh, Chien-Sheng Hsu & Ming-Chia Hsieh
Pages: 4645-4665
Published online: 17 Jun 2020
AbstractforSynergistic Anticancer Effects of Gemcitabine with Pitavastatin on Pancreatic Cancer Cell Line MIA PaCa-2 in vitro and in vivo | Full Text | References | PDF (23.4 MB) | EPUB
  • 322 Views
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Article
Monitoring Value of Serum HER2 as a Predictive Biomarker in Patients with Metastatic Breast Cancer
Pengyu Zhang, Jun Xiao, Yingxin Ruan, Zhenzhen Zhang & Xuejun Zhang
Pages: 4667-4675
Published online: 18 Jun 2020
AbstractforMonitoring Value of Serum HER2 as a Predictive Biomarker in Patients with Metastatic Breast Cancer | Full Text | References | PDF (458.1 KB) | EPUB
  • 137 Views
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Article
DNA Methylation in RARβ Gene as a Mediator of the Association Between Healthy Lifestyle and Breast Cancer: A Case–Control Study
Xuan Wang, Yupeng Liu, Hongru Sun, Anqi Ge, Dapeng Li, Jinming Fu, Yan Li, Da Pang & Yashuang Zhao
Pages: 4677-4684
Published online: 18 Jun 2020
AbstractforDNA Methylation in RARβ Gene as a Mediator of the Association Between Healthy Lifestyle and Breast Cancer: A Case–Control Study | Full Text | References | PDF (459.2 KB) | EPUB
  • 70 Views
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Article
CFTR Regulates the Proliferation, Migration and Invasion of Cervical Cancer Cells by Inhibiting the NF-κB Signalling Pathway
Zhao Wu, Jinke Li, Yi Zhang, Lina Hu & Xue Peng
Pages: 4685-4697
Published online: 18 Jun 2020
AbstractforCFTR Regulates the Proliferation, Migration and Invasion of Cervical Cancer Cells by Inhibiting the NF-κB Signalling Pathway | Full Text | References | PDF (16.8 MB) | EPUB
  • 101 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma
Jinghua Fan, Xiaoxiao Kang, Limin Zhao, Yan Zheng, Jun Yang & Di Li
Pages: 4699-4714
Published online: 18 Jun 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma | PDF (13.7 MB)
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Article
Overexpression of lncRNA MT1JP Mediates Apoptosis and Migration of Hepatocellular Carcinoma Cells by Regulating miR-24-3p
Qiu-Li Shan, Ning-Ning Chen, Gui-Zhi Meng & Fan Qu
Pages: 4715-4724
Published online: 18 Jun 2020
AbstractforOverexpression of lncRNA MT1JP Mediates Apoptosis and Migration of Hepatocellular Carcinoma Cells by Regulating miR-24-3p | Full Text | References | PDF (6.3 MB) | EPUB
  • 67 Views
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Case Series

Case Report
Optimal Laparoscopic Management and Oncological Outcomes of Gastrointestinal Stromal Tumors in Duodenum: Pancreaticoduodenectomy or Pancreas-Sparing Duodenectomy?
Chao Lu, Weiwei Jin, Yiping Mou, Hongliang Shao, Xiaosan Wu, Shaodong Li, Biwu Xu, Yuanyu Wang, Qicong Zhu, Tao Xia & Yucheng Zhou
Pages: 4725-4734
Published online: 19 Jun 2020
AbstractforOptimal Laparoscopic Management and Oncological Outcomes of Gastrointestinal Stromal Tumors in Duodenum: Pancreaticoduodenectomy or Pancreas-Sparing Duodenectomy? | Full Text | References | PDF (2.3 MB) | EPUB
  • 102 Views
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Original Research

Article
Upregulated SET Promotes Cell Survival Through Activating Akt/NF-κB Signal in Colorectal Carcinoma
Jianjun Zhu, Lihong Shi, Genlai Du, Li Li & Ming Liu
Pages: 4735-4745
Published online: 19 Jun 2020
AbstractforUpregulated SET Promotes Cell Survival Through Activating Akt/NF-κB Signal in Colorectal Carcinoma | Full Text | References | PDF (7.3 MB) | EPUB
  • 63 Views
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Article
Knockdown of lncRNA HCP5 Suppresses the Progression of Colorectal Cancer by miR-299-3p/PFN1/AKT Axis
Ni Bai, Ying Ma, Jia Zhao & Bo Li
Pages: 4747-4758
Published online: 19 Jun 2020
AbstractforKnockdown of lncRNA HCP5 Suppresses the Progression of Colorectal Cancer by miR-299-3p/PFN1/AKT Axis | Full Text | References | PDF (10.5 MB) | EPUB
  • 65 Views
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Article
RETRACTED ARTICLE: The Role and Mechanism of S1PR5 in Colon Cancer
Huijun Zhou, Xianli Yin, Fei Bai, Wu Liu, Shaofeng Jiang & Jinfeng Zhao
Pages: 4759-4775
Published online: 19 Jun 2020
AbstractforRETRACTED ARTICLE: The Role and Mechanism of S1PR5 in Colon Cancer | PDF (10 MB)
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Article
Inhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib
Xiaowen Chen, Zhenqi Huang, Wei Wu & Ruixiang Xia
Pages: 4777-4787
Published online: 22 Jun 2020
AbstractforInhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib | Full Text | References | PDF (6.6 MB) | EPUB
  • 61 Views
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Review

Review Article
Biochemical Markers of Colorectal Cancer – Present and Future
Wojciech Jelski & Barbara Mroczko
Pages: 4789-4797
Published online: 22 Jun 2020
AbstractforBiochemical Markers of Colorectal Cancer – Present and Future | Full Text | References | PDF (384.3 KB) | EPUB
  • 661 Views
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Original Research

Article
MiR-34a Inhibits Cell Proliferation and Induces Apoptosis in Human Nasopharyngeal Carcinoma by Targeting lncRNA MCM3AP-AS1
Piyun Sun, Yuchen Feng, Hui Guo, Rong Li, Peng Yu, Xingguang Zhou, Zhige Pan, Yanyan Liang, Bihan Yu, Yanyi Zheng, Yu Shi, Lingbo Wen, Minmei Wei & Yanhua Chen
Pages: 4799-4806
Published online: 22 Jun 2020
AbstractforMiR-34a Inhibits Cell Proliferation and Induces Apoptosis in Human Nasopharyngeal Carcinoma by Targeting lncRNA MCM3AP-AS1 | Full Text | References | PDF (5.7 MB) | EPUB
  • 63 Views
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Article
The Regulatory Role of circRNA_101308 in Cervical Cancer and the Prediction of Its Mechanism
Jun Jiao, Xinlin Jiao, Qingqing Liu, Wenjie Qu, Daoxin Ma, Youzhong Zhang & Baoxia Cui
Pages: 4807-4815
Published online: 22 Jun 2020
AbstractforThe Regulatory Role of circRNA_101308 in Cervical Cancer and the Prediction of Its Mechanism | Full Text | References | PDF (4.6 MB) | EPUB
  • 111 Views
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Article
Aurora-B Promotes Osteosarcoma Cell Growth and Metastasis Through Activation of the NPM1/ERK/NF-κβ/MMPs Axis
Honghai Song, Yang Zhou, Aifen Peng, Jiaming Liu, Xin Wu, Wenzhao Chen & Zhili Liu
Pages: 4817-4827
Published online: 23 Jun 2020
AbstractforAurora-B Promotes Osteosarcoma Cell Growth and Metastasis Through Activation of the NPM1/ERK/NF-κβ/MMPs Axis | Full Text | References | PDF (9.2 MB) | EPUB
  • 92 Views
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Article
Information Seeking Behavior About Cancer and Associated Factors Among University Students, Ethiopia: A Cross-Sectional Study
Adugna Gedefaw, Tesfahun Melese Yilma & Berhanu Fikadie Endehabtu
Pages: 4829-4839
Published online: 22 Jun 2020
AbstractforInformation Seeking Behavior About Cancer and Associated Factors Among University Students, Ethiopia: A Cross-Sectional Study | Full Text | References | PDF (920.3 KB) | EPUB
  • 431 Views
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Article
Proteomics of Sentinel Lymph Nodes in Early Breast Cancer for Identification of Thymidylate Synthase as a Potential Biomarker to Flag Metastasis: A Preliminary Study
Sheetal Pathania, Mohd Imran Khan, Abhishek Kumar, Ashish Kumar Gupta, Komal Rani, Tanvi Ramesh Parashar, Jnaneshwari Jayaram, Piyush Ranjan Mishra, Anurag Srivastava, Sandeep Mathur, Smriti Hari & Gururao Hariprasad
Pages: 4841-4854
Published online: 23 Jun 2020
AbstractforProteomics of Sentinel Lymph Nodes in Early Breast Cancer for Identification of Thymidylate Synthase as a Potential Biomarker to Flag Metastasis: A Preliminary Study | Full Text | References | PDF (9.6 MB) | EPUB
  • 138 Views
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Article
A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma
Zhongjing Lv, Kun Wu, Xing Qin, Jian Yuan, Ming Yan, Jianjun Zhang, Lizhen Wang, Tong Ji, Wei Cao & Wantao Chen
Pages: 4855-4869
Published online: 23 Jun 2020
AbstractforA Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma | Full Text | References | PDF (12.7 MB) | EPUB
  • 94 Views
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Review

Review Article
Ipilimumab and Nivolumab as First-Line Treatment of Patients with Renal Cell Carcinoma: The Evidence to Date
Iris Y Sheng & Moshe C Ornstein
Pages: 4871-4881
Published online: 23 Jun 2020
AbstractforIpilimumab and Nivolumab as First-Line Treatment of Patients with Renal Cell Carcinoma: The Evidence to Date | Full Text | References | PDF (349 KB) | EPUB
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Original Research

Article
Evaluating the Effect of Cryptorchidism on Clinical Stage of Testicular Seminoma
Xingyuan Wang, Zeyu Chen, Shi Qiu, Dehong Cao, Kun Jin, Jin Li, Bo Chen, Yin Huang, Yige Bao, Liangren Liu & Qiang Wei
Pages: 4883-4888
Published online: 23 Jun 2020
AbstractforEvaluating the Effect of Cryptorchidism on Clinical Stage of Testicular Seminoma | Full Text | References | PDF (509.4 KB) | EPUB
  • 112 Views
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Article
CCNY Accelerates Cylcin E Expression to Regulate the Proliferation of Laryngeal Carcinoma Cells via MEK/ERK Signaling Pathway
Xiaoting Zhao, Mei Jiang, Ziyu Wang, Xiaohong Chen, Hongzhen Wang, Wentao Yue & Chao Cai
Pages: 4889-4898
Published online: 23 Jun 2020
AbstractforCCNY Accelerates Cylcin E Expression to Regulate the Proliferation of Laryngeal Carcinoma Cells via MEK/ERK Signaling Pathway | Full Text | References | PDF (7.2 MB) | EPUB
  • 74 Views
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Article
CircRNA SMARCC1 Sponges MiR-140-3p to Regulate Cell Progression in Colorectal Cancer
Miao-sheng Chen, Cui-hong Lin, Ling-yan Huang & Xiao-ming Qiu
Pages: 4899-4910
Published online: 23 Jun 2020
AbstractforCircRNA SMARCC1 Sponges MiR-140-3p to Regulate Cell Progression in Colorectal Cancer | Full Text | References | PDF (11.5 MB) | EPUB
  • 73 Views
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Article
Impact of Amrubicin Monotherapy as Second-Line Chemotherapy on Outcomes in Elderly Patients with Relapsed Extensive-Disease Small-Cell Lung Cancer
Satoshi Igawa, Taihei Ono, Masashi Kasajima, Hideaki Manabe, Tomoya Fukui, Hisashi Mitsufuji, Masanori Yokoba, Masaru Kubota, Masato Katagiri, Jiichiro Sasaki & Katsuhiko Naoki
Pages: 4911-4921
Published online: 23 Jun 2020
AbstractforImpact of Amrubicin Monotherapy as Second-Line Chemotherapy on Outcomes in Elderly Patients with Relapsed Extensive-Disease Small-Cell Lung Cancer | Full Text | References | PDF (681.3 KB) | EPUB
  • 59 Views
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Article
Glucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma
Dezhi Li, Xianyi Cheng, Wei Zheng & Junhui Chen
Pages: 4923-4935
Published online: 24 Jun 2020
AbstractforGlucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma | Full Text | References | PDF (12.1 MB) | EPUB
  • 101 Views
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Article
Anlotinib Suppresses Colorectal Cancer Proliferation and Angiogenesis via Inhibition of AKT/ERK Signaling Cascade
Qian Yang, Laichao Ni, Saber Imani, Zhangqiang Xiang, Rui Hai, Ruilin Ding, Shaozhi Fu, Jing bo Wu & Qinglian Wen
Pages: 4937-4948
Published online: 24 Jun 2020
AbstractforAnlotinib Suppresses Colorectal Cancer Proliferation and Angiogenesis via Inhibition of AKT/ERK Signaling Cascade | Full Text | References | PDF (7.4 MB) | EPUB
  • 149 Views
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Article
Down-Regulation of Ribosomal Protein RPS21 Inhibits Invasive Behavior of Osteosarcoma Cells Through the Inactivation of MAPK Pathway
Tao Wang, Zhi-Yong Wang, Ling-Yuan Zeng, Yao-Zu Gao, Yu-Xin Yan & Quan Zhang
Pages: 4949-4955
Published online: 25 Jun 2020
AbstractforDown-Regulation of Ribosomal Protein RPS21 Inhibits Invasive Behavior of Osteosarcoma Cells Through the Inactivation of MAPK Pathway | Full Text | References | PDF (2.4 MB) | EPUB
  • 94 Views
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Corrigendum

Correction
Validation of the Chinese Version of the Shame and Stigma Scale in Patients with Head and Neck Cancer [Corrigendum]
Page: 4957
Published online: 25 Jun 2020
CitationforValidation of the Chinese Version of the Shame and Stigma Scale in Patients with Head and Neck Cancer [Corrigendum] | Full Text | PDF (144.6 KB) | EPUB
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Original Research

Article
Association Between Contrast-Enhanced Ultrasound Indicators and Prostate Cancer Biochemical Recurrence After Treatment
Jiang-jun Mei, Yun-xin Zhao, Yi Jiang, Jian Wang & Jia-shun Yu
Pages: 4959-4968
Published online: 25 Jun 2020
AbstractforAssociation Between Contrast-Enhanced Ultrasound Indicators and Prostate Cancer Biochemical Recurrence After Treatment | Full Text | References | PDF (5 MB) | EPUB
  • 83 Views
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Article
Nosocomial Infections in Gastrointestinal Cancer Patients: Bacterial Profile, Antibiotic Resistance Pattern, and Prognostic Factors
Ai-Min Jiang, Na Liu, Rim Ali Said, Meng-Di Ren, Huan Gao, Xiao-Qiang Zheng, Xiao Fu, Xuan Liang, Zhi-Ping Ruan, Yu Yao & Tao Tian
Pages: 4969-4979
Published online: 25 Jun 2020
AbstractforNosocomial Infections in Gastrointestinal Cancer Patients: Bacterial Profile, Antibiotic Resistance Pattern, and Prognostic Factors | Full Text | References | PDF (1.3 MB) | EPUB
  • 278 Views
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Article
miRNA-181a-5p Enhances the Sensitivity of Cells to Cisplatin in Esophageal Adenocarcinoma by Targeting CBLB
Song Yang, Peng Wang, Songhua Wang, Aihua Cong, Qi Zhang, Wenhao Shen, Xiangyi Li, Wei Zhang & Gaohua Han
Pages: 4981-4990
Published online: 25 Jun 2020
AbstractformiRNA-181a-5p Enhances the Sensitivity of Cells to Cisplatin in Esophageal Adenocarcinoma by Targeting CBLB | Full Text | References | PDF (6.4 MB) | EPUB
  • 68 Views
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Article
Antibiotics Modulate Chemotherapy Efficacy in Patients with Esophageal Cancer
Chensi Wu, Ruixue Lai, Jing Li, Jingjing Zhang, Yufei Zhao, Xiaoyun Zhang, Yue Zhao & Zhanjun Guo
Pages: 4991-4997
Published online: 25 Jun 2020
AbstractforAntibiotics Modulate Chemotherapy Efficacy in Patients with Esophageal Cancer | Full Text | References | PDF (1.5 MB) | EPUB
  • 83 Views
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Article
PD-L1 and miR-34a are Prognostic Factors for Primary Gastric Diffuse Large B-Cell Lymphoma Patients Treated with R-CHOP
Jinfeng Wang, Song Shang, Junjun Li, Hongyu Deng, Linda Ouyang, Hailong Xie, Haizhen Zhu, Yajun Li & Chaohui Zuo
Pages: 4999-5008
Published online: 25 Jun 2020
AbstractforPD-L1 and miR-34a are Prognostic Factors for Primary Gastric Diffuse Large B-Cell Lymphoma Patients Treated with R-CHOP | Full Text | References | PDF (3.5 MB) | EPUB
  • 64 Views
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Article
RETRACTED ARTICLE: Lidocaine Suppresses Cell Proliferation and Aerobic Glycolysis by Regulating circHOMER1/miR-138-5p/HEY1 Axis in Colorectal Cancer
Juan Du, Liying Zhang, Hongzhong Ma, Yang Wang & Pengpeng Wang
Pages: 5009-5022
Published online: 25 Jun 2020
AbstractforRETRACTED ARTICLE: Lidocaine Suppresses Cell Proliferation and Aerobic Glycolysis by Regulating circHOMER1/miR-138-5p/HEY1 Axis in Colorectal Cancer | PDF (9 MB)
  • 11 Views
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Article
Increased Serum Calcium Level Promotes the Risk of Lymph Node Metastasis in Endometrial Cancer
Xing-Chen Li, Yang-Yang Dong, Yuan Cheng, Jing-Yi Zhou, Xiao Yang, Bo-Qiang Shen, Xiao-Tong Wu, Xiao-Ping Li & Jian-Liu Wang
Pages: 5023-5030
Published online: 25 Jun 2020
AbstractforIncreased Serum Calcium Level Promotes the Risk of Lymph Node Metastasis in Endometrial Cancer | Full Text | References | PDF (333.3 KB) | EPUB
  • 87 Views
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Article
Chinese Cancer Research in 2009–18 and the Disease Burden
Aihua Li & Grant Lewison
Pages: 5031-5040
Published online: 25 Jun 2020
AbstractforChinese Cancer Research in 2009–18 and the Disease Burden | Full Text | References | PDF (6.1 MB) | EPUB
  • 86 Views
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Article
Switching Fractioned R-CHOP Cycles to Standard R-CHOP Cycles Guided by Endoscopic Ultrasonography in Treating Patients with Primary Gastric Diffuse Large B-Cell Lymphoma
Yizhen Liu, Yumei Liu, Ping Zhao, Qunling Zhang, Xiaojian Liu, Fangfang Lv, Xiaonan Hong, Junning Cao & Kai Xue
Pages: 5041-5048
Published online: 25 Jun 2020
AbstractforSwitching Fractioned R-CHOP Cycles to Standard R-CHOP Cycles Guided by Endoscopic Ultrasonography in Treating Patients with Primary Gastric Diffuse Large B-Cell Lymphoma | Full Text | References | PDF (5 MB) | EPUB
  • 81 Views
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Article
Circular RNA FOXO3 Suppresses Bladder Cancer Progression and Metastasis by Regulating MiR-9-5p/TGFBR2
Yongxiang Li, Liang Qiao, Yuanwei Zang, Wenjun Ni & Zhonghua Xu
Pages: 5049-5056
Published online: 25 Jun 2020
AbstractforCircular RNA FOXO3 Suppresses Bladder Cancer Progression and Metastasis by Regulating MiR-9-5p/TGFBR2 | Full Text | References | PDF (4.7 MB) | EPUB
  • 82 Views
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Article
Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation
Ruoyao Zou, Mingjun Zheng, Mingzi Tan, Haoya Xu, Nannan Luan & Liancheng Zhu
Pages: 5057-5075
Published online: 26 Jun 2020
AbstractforDecreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation | Full Text | References | PDF (13.5 MB) | EPUB
  • 141 Views
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Article
Chemotherapy of Locally Advanced or Metastatic Urothelial Cell Carcinoma: Monocentric Real-Life Data
Christine Fischer, Rainer Hofmann & Axel Hegele
Pages: 5077-5084
Published online: 26 Jun 2020
AbstractforChemotherapy of Locally Advanced or Metastatic Urothelial Cell Carcinoma: Monocentric Real-Life Data | Full Text | References | PDF (886.1 KB) | EPUB
  • 69 Views
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Article
Sevoflurane Regulates Glioma Progression by Circ_0002755/miR-628-5p/MAGT1 Axis
Haoyi Li, Tian Xia, Yilin Guan & Yao Yu
Pages: 5085-5098
Published online: 30 Jun 2020
AbstractforSevoflurane Regulates Glioma Progression by Circ_0002755/miR-628-5p/MAGT1 Axis | Full Text | References | PDF (12 MB) | EPUB
  • 69 Views
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Article
Histopathological Diagnosis of Cervical Biopsies: Reduction of Sampling Errors with the Evaluation of a Third Histologic Level
Edgar Villegas-Hinojosa, Yolanda Terán-Figueroa, Veronica Gallegos-García, Dario Gaytán-Hernández, Sandra O Gutiérrez-Enríquez, Anahid E Campuzano-Barajas & Luz E Alcántara-Quintana
Pages: 5099-5104
Published online: 26 Jun 2020
AbstractforHistopathological Diagnosis of Cervical Biopsies: Reduction of Sampling Errors with the Evaluation of a Third Histologic Level | Full Text | References | PDF (2.1 MB) | EPUB
  • 103 Views
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Article
Clinical Significance of Red Cell Distribution Width and Circulating Tumor Cells with an Epithelial–Mesenchymal Transition Phenotype in Lung Adenocarcinoma
Huajian Peng, Xiang Tan, Yongyong Wang, Lei Dai, Guanbiao Liang, Jianji Guo & Mingwu Chen
Pages: 5105-5117
Published online: 26 Jun 2020
AbstractforClinical Significance of Red Cell Distribution Width and Circulating Tumor Cells with an Epithelial–Mesenchymal Transition Phenotype in Lung Adenocarcinoma | Full Text | References | PDF (4.2 MB) | EPUB
  • 102 Views
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Article
The Novel Zinc Finger Protein 587B Gene, ZNF587B, Regulates Cell Proliferation and Metastasis in Ovarian Cancer Cells in vivo and in vitro
Yujie Liu, Qianying Ouyang, Zeen Sun, Jieqiong Tan, Weihua Huang, Jie Liu, Zhaoqian Liu, Honghao Zhou, Feiyue Zeng & Yingzi Liu
Pages: 5119-5130
Published online: 26 Jun 2020
AbstractforThe Novel Zinc Finger Protein 587B Gene, ZNF587B, Regulates Cell Proliferation and Metastasis in Ovarian Cancer Cells in vivo and in vitro | Full Text | References | PDF (11 MB) | EPUB
  • 92 Views
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Article
Anticancer Effects of ACT001 via NF-κB Suppression in Murine Triple-Negative Breast Cancer Cell Line 4T1
Yanyang Liu, Li Wang, Jiewei Liu, Xiaoxiao Xie, Haoyue Hu & Feng Luo
Pages: 5131-5139
Published online: 26 Jun 2020
AbstractforAnticancer Effects of ACT001 via NF-κB Suppression in Murine Triple-Negative Breast Cancer Cell Line 4T1 | Full Text | References | PDF (4.8 MB) | EPUB
  • 180 Views
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Article
Lobaplatin in Prophylactic Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer: Safety and Efficacy Profiles
Yuxin Zhong, Jing Zhang, Xiaofeng Bai, Yuemin Sun, Hao Liu, Shuai Ma, Yang Li, Wenzhe Kang, Fuhai Ma, Weikun Li & Yantao Tian
Pages: 5141-5146
Published online: 29 Jun 2020
AbstractforLobaplatin in Prophylactic Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer: Safety and Efficacy Profiles | Full Text | References | PDF (1.6 MB) | EPUB
  • 75 Views
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Article
Magnetic Resonance Diffusion Kurtosis Imaging versus Diffusion-Weighted Imaging in Evaluating the Pathological Grade of Hepatocellular Carcinoma
Guang-Zhi Wang, Ling-Fei Guo, Gui-Hua Gao, Yao Li, Xi-Zhen Wang & Zhen-Guo Yuan
Pages: 5147-5158
Published online: 29 Jun 2020
AbstractforMagnetic Resonance Diffusion Kurtosis Imaging versus Diffusion-Weighted Imaging in Evaluating the Pathological Grade of Hepatocellular Carcinoma | Full Text | References | PDF (4.1 MB) | EPUB
  • 88 Views
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Article
Molecular Alterations in Circulating Cell-Free DNA in Patients with Colorectal Adenoma or Carcinoma
Ying Hu, Yawei Chen, Hao Guo, Jianing Yu, Yanhui Chen, Yang Liu, Ling Lan, Jian Li, Huaqing Wang & Henghui Zhang
Pages: 5159-5167
Published online: 30 Jun 2020
AbstractforMolecular Alterations in Circulating Cell-Free DNA in Patients with Colorectal Adenoma or Carcinoma | Full Text | References | PDF (1.2 MB) | EPUB
  • 69 Views
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Article
Risk Factors and Clinical Significance of D-Dimer in the Development of Postoperative Venous Thrombosis in Patients with Lung Tumor
Pan Wang, Honglin Zhao, Qingchun Zhao, Fan Ren, Ruifeng Shi, Xingyu Liu, Jinghao Liu, Hongyu Liu, Gang Chen & Jun Chen
Pages: 5169-5179
Published online: 30 Jun 2020
AbstractforRisk Factors and Clinical Significance of D-Dimer in the Development of Postoperative Venous Thrombosis in Patients with Lung Tumor | Full Text | References | PDF (4.9 MB) | EPUB
  • 126 Views
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Article
LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer
Wei Xu, Minhao Yu, Jun Qin, Yang Luo & Ming Zhong
Pages: 5181-5200
Published online: 30 Jun 2020
AbstractforLACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer | Full Text | References | PDF (17.9 MB) | EPUB
  • 193 Views
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Article
microRNA-582 Potentiates Liver and Lung Metastasis of Gastric Carcinoma Cells Through the FOXO3-Mediated PI3K/Akt/Snail Pathway
Tianyu Xie, Di Wu, Shuo Li, Xiongguang Li, Lipeng Wang, Yixun Lu, Qiying Song, Xuehong Sun & Xinxin Wang
Pages: 5201-5212
Published online: 30 Jun 2020
AbstractformicroRNA-582 Potentiates Liver and Lung Metastasis of Gastric Carcinoma Cells Through the FOXO3-Mediated PI3K/Akt/Snail Pathway | Full Text | References | PDF (11.4 MB) | EPUB
  • 83 Views
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Article
Identification of Chemoresistance-Associated Key Genes and Pathways in High-Grade Serous Ovarian Cancer by Bioinformatics Analyses
Yong Wu, Lingfang Xia, Qinhao Guo, Jun Zhu, Yu Deng & Xiaohua Wu
Pages: 5213-5223
Published online: 30 Jun 2020
AbstractforIdentification of Chemoresistance-Associated Key Genes and Pathways in High-Grade Serous Ovarian Cancer by Bioinformatics Analyses | Full Text | References | PDF (5.8 MB) | EPUB
  • 152 Views
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Review

Review Article
Biomarkers That Differentiate Benign Prostatic Hyperplasia from Prostate Cancer: A Literature Review
Christopher J McNally, Mark W Ruddock, Tara Moore & Declan J McKenna
Pages: 5225-5241
Published online: 01 Jul 2020
AbstractforBiomarkers That Differentiate Benign Prostatic Hyperplasia from Prostate Cancer: A Literature Review | Full Text | References | PDF (602.5 KB) | EPUB
  • 638 Views
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Original Research

Article
Honokiol Suppressed Pancreatic Cancer Progression via miR-101/Mcl-1 Axis
Yishuo Wang, Zhongyong Liu, Qinrong Liu, Yongguang Han, Yuncai Zang, Huichao Zhang, Xuzhao Du, Tao Qin & Yuquan Wu
Pages: 5243-5254
Published online: 01 Jul 2020
AbstractforHonokiol Suppressed Pancreatic Cancer Progression via miR-101/Mcl-1 Axis | Full Text | References | PDF (9.4 MB) | EPUB
  • 118 Views
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Article
The Efficacy and Safety of Apatinib in Advanced Synovial Sarcoma: A Case Series of Twenty-One Patients in One Single Institution
Yitian Wang, Minxun Lu, Yong Zhou, Sisi Zhou, Xinzhu Yu, Fan Tang, Yi Luo, Wenli Zhang, Hong Duan, Li Min & Chongqi Tu
Pages: 5255-5264
Published online: 01 Jul 2020
AbstractforThe Efficacy and Safety of Apatinib in Advanced Synovial Sarcoma: A Case Series of Twenty-One Patients in One Single Institution | Full Text | References | PDF (862.1 KB) | EPUB
  • 92 Views
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Article
The Efficiency of Type-Specific High-Risk Human Papillomavirus Models in the Triage of Women with Atypical Squamous Cells of Undetermined Significance
Yangzhen Wang, Shanshan Gao, Yuxia Wang, Fuchun Chen, Hailong Deng & Yongfang Lu
Pages: 5265-5275
Published online: 01 Jul 2020
AbstractforThe Efficiency of Type-Specific High-Risk Human Papillomavirus Models in the Triage of Women with Atypical Squamous Cells of Undetermined Significance | Full Text | References | PDF (3.3 MB) | EPUB
  • 62 Views
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Article
LncRNA PSMA3-AS1 Promotes Lung Cancer Growth and Invasion via Sponging MiR-4504
Fangfang Li, LianLing Yu & Jun Zhu
Pages: 5277-5283
Published online: 01 Jul 2020
AbstractforLncRNA PSMA3-AS1 Promotes Lung Cancer Growth and Invasion via Sponging MiR-4504 | Full Text | References | PDF (4.7 MB) | EPUB
  • 69 Views
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Article
lncRNA NR4A1AS Upregulates miR-221 Through Demethylation to Promote Cell Proliferation in Oral Squamous Cell Carcinoma
Liuqing Yang, Guanghui Li, Ya Gao, Nini Ou, Tingting Yu & Shirong Ren
Pages: 5285-5292
Published online: 02 Jul 2020
AbstractforlncRNA NR4A1AS Upregulates miR-221 Through Demethylation to Promote Cell Proliferation in Oral Squamous Cell Carcinoma | Full Text | References | PDF (4 MB) | EPUB
  • 64 Views
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Article
Mapping of Regional Failures After Definitive Radiotherapy in Patients with Locally Advanced Cervical Esophageal Carcinoma
Dan Zhao, Baomin Zheng, Shaowen Xiao, Weixin Liu, Xiaolong Xu, Huiming Yu, Yan Sun & Weihu Wang
Pages: 5293-5299
Published online: 02 Jul 2020
AbstractforMapping of Regional Failures After Definitive Radiotherapy in Patients with Locally Advanced Cervical Esophageal Carcinoma | Full Text | References | PDF (831 KB) | EPUB
  • 78 Views
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Article
RETRACTED ARTICLE: miR-4429 Regulates the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Cervical Cancer by Targeting FOXM1
Lin Liang, Yu Wei Zheng & Yan Li Wang
Pages: 5301-5312
Published online: 02 Jul 2020
AbstractforRETRACTED ARTICLE: miR-4429 Regulates the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Cervical Cancer by Targeting FOXM1 | PDF (6.4 MB)
  • 35 Views
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Article
PWRN1 Suppressed Cancer Cell Proliferation and Migration in Glioblastoma by Inversely Regulating hsa-miR-21-5p
Jianxin Jiang, Xiaolin Wang & Jun Lu
Pages: 5313-5322
Published online: 02 Jul 2020
AbstractforPWRN1 Suppressed Cancer Cell Proliferation and Migration in Glioblastoma by Inversely Regulating hsa-miR-21-5p | Full Text | References | PDF (6.9 MB) | EPUB
  • 112 Views
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Article
Eradication of Hepatitis C Virus (HCV) Improves Survival of Hepatocellular Carcinoma Patients with Active HCV Infection – A Real-World Cohort Study
Yang Luo, Yue Zhang, Di Wang, Di Shen & Yi-Qun Che
Pages: 5323-5330
Published online: 02 Jul 2020
AbstractforEradication of Hepatitis C Virus (HCV) Improves Survival of Hepatocellular Carcinoma Patients with Active HCV Infection – A Real-World Cohort Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 60 Views
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Article
Clinical Outcomes of N3 Breast Cancer: A Real-World Study of a Single Institution and the US Surveillance, Epidemiology, and End Results (SEER) Database
Xiang Ai, Xin Liao, Junyan Li, Peng Tang & Jun Jiang
Pages: 5331-5343
Published online: 02 Jul 2020
AbstractforClinical Outcomes of N3 Breast Cancer: A Real-World Study of a Single Institution and the US Surveillance, Epidemiology, and End Results (SEER) Database | Full Text | References | PDF (4.4 MB) | EPUB
  • 129 Views
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Article
Efficacy and Safety of Apatinib in Treatment of Unresectable Intrahepatic Cholangiocarcinoma: An Observational Study
Yubin Hu, Hailan Lin, Mingzhi Hao, Yan Zhou, Qizhong Chen & Zhangxian Chen
Pages: 5345-5351
Published online: 03 Jul 2020
AbstractforEfficacy and Safety of Apatinib in Treatment of Unresectable Intrahepatic Cholangiocarcinoma: An Observational Study | Full Text | References | PDF (1,006 KB) | EPUB
  • 69 Views
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Article
Signatures of Mucosal Microbiome in Oral Squamous Cell Carcinoma Identified Using a Random Forest Model
Jianhua Zhou, Lili Wang, Rongtao Yuan, Xinjuan Yu, Zhenggang Chen, Fang Yang, Guirong Sun & Quanjiang Dong
Pages: 5353-5363
Published online: 03 Jul 2020
AbstractforSignatures of Mucosal Microbiome in Oral Squamous Cell Carcinoma Identified Using a Random Forest Model | Full Text | References | PDF (5.7 MB) | EPUB
  • 242 Views
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Article
Regorafenib for Metastatic Colorectal Cancer: An Analysis of a Registry-Based Cohort of 555 Patients
Alena Novakova-Jiresova, Katerina Kopeckova, Ludmila Boublikova, Renata Chloupkova, Bohuslav Melichar, Lubos Petruzelka, Jindrich Finek, Ondrej Fiala, Peter Grell, Stanislav Batko, Zdenek Linke, Igor Kiss, Jana Prausova & Tomas Buchler
Pages: 5365-5372
Published online: 03 Jul 2020
AbstractforRegorafenib for Metastatic Colorectal Cancer: An Analysis of a Registry-Based Cohort of 555 Patients | Full Text | References | PDF (384.5 KB) | EPUB
  • 115 Views
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Article
Prediction of Poor Outcomes in Patients with Colorectal Cancer: Elevated Preoperative Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT)
Lin Zhang, Juan Ye, Qiuyun Luo, Miaohuan Kuang, Minjie Mao, Shuqin Dai & Xueping Wang
Pages: 5373-5384
Published online: 03 Jul 2020
AbstractforPrediction of Poor Outcomes in Patients with Colorectal Cancer: Elevated Preoperative Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) | Full Text | References | PDF (2.5 MB) | EPUB
  • 184 Views
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Article
Construction and Validation of an m6A RNA Methylation Regulators-Based Prognostic Signature for Esophageal Cancer
Li-chao Xu, Jing-xin Pan & Hong-da Pan
Pages: 5385-5394
Published online: 06 Jul 2020
AbstractforConstruction and Validation of an m6A RNA Methylation Regulators-Based Prognostic Signature for Esophageal Cancer | Full Text | References | PDF (6.9 MB) | EPUB
  • 117 Views
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Article
lncRNA PCBP1-AS1 Aggravates the Progression of Hepatocellular Carcinoma via Regulating PCBP1/PRL-3/AKT Pathway
Tianping Luo, Yuan Gao, Guangyan Zhangyuan, Xiaoliang Xu, Cailin Xue, Lei Jin, Wenjie Zhang, Chunfu Zhu, Beicheng Sun & Xihu Qin
Pages: 5395-5408
Published online: 06 Jul 2020
AbstractforlncRNA PCBP1-AS1 Aggravates the Progression of Hepatocellular Carcinoma via Regulating PCBP1/PRL-3/AKT Pathway | Full Text | References | PDF (11.6 MB) | EPUB
  • 92 Views
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Article
Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer
Xue Chen, Qi Yu, Hailun Pan, Ping Li, Xufei Wang & Shen Fu
Pages: 5409-5418
Published online: 06 Jul 2020
AbstractforOverexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer | Full Text | References | PDF (4.6 MB) | EPUB
  • 96 Views
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Article
miR-22 Suppresses Tumor Invasion and Metastasis in Colorectal Cancer by Targeting NLRP3
Jinchun Cong, Jian Gong, Chuanjia Yang, Zhixiu Xia & Hong Zhang
Pages: 5419-5429
Published online: 06 Jul 2020
AbstractformiR-22 Suppresses Tumor Invasion and Metastasis in Colorectal Cancer by Targeting NLRP3 | Full Text | References | PDF (12.5 MB) | EPUB
  • 84 Views
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Review

Review Article
The Blood Biomarkers of Thyroid Cancer
Weiran Wang, Jingtao Chang, Baosong Jia & Jing Liu
Pages: 5431-5438
Published online: 06 Jul 2020
AbstractforThe Blood Biomarkers of Thyroid Cancer | Full Text | References | PDF (329.9 KB) | EPUB
  • 293 Views
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Original Research

Article
Predictors of Acquired T790M Mutation in Patients Failing First- or Second-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors
Chee-Shee Chai, Chong-Kin Liam, Mau-Ern Poh, Diana Bee-Lan Ong, Yong-Kek Pang, Phaik-Leng Cheah, Gwo-Fuang Ho & Adlinda Alip
Pages: 5439-5450
Published online: 06 Jul 2020
AbstractforPredictors of Acquired T790M Mutation in Patients Failing First- or Second-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors | Full Text | References | PDF (5.5 MB) | EPUB
  • 77 Views
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Article
Laparoscopic Resection and Pre-Operative Imaging of Primary Retroperitoneal Mucinous Neoplasms: A Retrospective Case Series
Yuyang Zhang, Jiejin Yang, Zeyang Chen, Jiali Sun & Pengyuan Wang
Pages: 5451-5460
Published online: 06 Jul 2020
AbstractforLaparoscopic Resection and Pre-Operative Imaging of Primary Retroperitoneal Mucinous Neoplasms: A Retrospective Case Series | Full Text | References | PDF (1.9 MB) | EPUB
  • 74 Views
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Article
Drug-Eluting Beads versus Lipiodol Transarterial Chemoembolization for the Treatment of Hypovascular Hepatocellular Carcinoma: A Single-Center Retrospective Study
Qin Shi, Dandan Chen, Chen Zhou, Jiacheng Liu, Songjiang Huang, Chongtu Yang & Bin Xiong
Pages: 5461-5468
Published online: 06 Jul 2020
AbstractforDrug-Eluting Beads versus Lipiodol Transarterial Chemoembolization for the Treatment of Hypovascular Hepatocellular Carcinoma: A Single-Center Retrospective Study | Full Text | References | PDF (973.9 KB) | EPUB
  • 55 Views
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Article
Circular RNA MYLK Promotes Glycolysis and Proliferation of Non-Small Cell Lung Cancer Cells by Sponging miR-195-5p and Increasing Glucose Transporter Member 3 Expression
Shuanglong Xiong, Dairong Li, Donglin Wang, Lumi Huang, Guanzhong Liang, Zhijuan Wu, Jianlin Long, Dan Yang, Yan Teng, Shuangyi Lei & Yan Li
Pages: 5469-5478
Published online: 07 Jul 2020
AbstractforCircular RNA MYLK Promotes Glycolysis and Proliferation of Non-Small Cell Lung Cancer Cells by Sponging miR-195-5p and Increasing Glucose Transporter Member 3 Expression | Full Text | References | PDF (7.2 MB) | EPUB
  • 75 Views
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Review

Review Article
First-Line Treatment  with Olaparib for Early Stage BRCA-Positive Ovarian Cancer: May It Be Possible? Hypothesis Potentially Generating a Line of Research
Federica Tomao, Serena Maria Boccia, Carolina Maria Sassu, Martina Chirra, Innocenza Palaia, Maria Cristina Petrella, Violante Di Donato, Nicoletta Colombo & Pierluigi Benedetti Panici
Pages: 5479-5489
Published online: 07 Jul 2020
AbstractforFirst-Line Treatment  with Olaparib for Early Stage BRCA-Positive Ovarian Cancer: May It Be Possible? Hypothesis Potentially Generating a Line of Research | Full Text | References | PDF (538.3 KB) | EPUB
  • 101 Views
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Original Research

Article
miRNA Expression Profile in the N2 Phenotype Neutrophils of Colorectal Cancer and Screen of Putative Key miRNAs
Liang Wang, Jun Yang, Jian Huang, Zheng-Qi Wen, Ning Xu, Xuan Liu, Jian-Hua Zhang & Wen-Liang Li
Pages: 5491-5503
Published online: 07 Jul 2020
AbstractformiRNA Expression Profile in the N2 Phenotype Neutrophils of Colorectal Cancer and Screen of Putative Key miRNAs | Full Text | References | PDF (7.6 MB) | EPUB
  • 115 Views
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Article
Predictive Value of Postoperative Peripheral CD4+ T Cells Percentage in Stage I–III Colorectal Cancer: A Retrospective Multicenter Cohort Study of 1028 Subjects
Zhenhui Li, Shaoyou Li, Yun Liang, Hongjiang Pu, Changling Tu, Zhenyu Wu & Dingyun You
Pages: 5505-5513
Published online: 07 Jul 2020
AbstractforPredictive Value of Postoperative Peripheral CD4+ T Cells Percentage in Stage I–III Colorectal Cancer: A Retrospective Multicenter Cohort Study of 1028 Subjects | Full Text | References | PDF (467.1 KB) | EPUB
  • 66 Views
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Article
Effects of Anesthetic Technique on Postoperative Pulmonary Metastasis in Patients Undergoing Laryngectomy
Xuan-Wei Huang, Xu-Dong Wang, Jie-Lan Lai, Ya-Li Lu, Kun Deng & Ren-Chun Lai
Pages: 5515-5525
Published online: 07 Jul 2020
AbstractforEffects of Anesthetic Technique on Postoperative Pulmonary Metastasis in Patients Undergoing Laryngectomy | Full Text | References | PDF (2 MB) | EPUB
  • 70 Views
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Article
lncRNA TM4SF1-AS1 Activates the PI3K/AKT Signaling Pathway and Promotes the Migration and Invasion of Lung Cancer Cells
Fachen Zhou, Jin Wang, Xinming Chi, Xin Zhou & Zhou Wang
Pages: 5527-5536
Published online: 07 Jul 2020
AbstractforlncRNA TM4SF1-AS1 Activates the PI3K/AKT Signaling Pathway and Promotes the Migration and Invasion of Lung Cancer Cells | Full Text | References | PDF (4.7 MB) | EPUB
  • 101 Views
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Article
A Novel Pathological Scoring System for Hepatic Cirrhosis with Hepatocellular Carcinoma
Wei Dong, Hua Yu, Yu-Yao Zhu, Zhi-Hong Xian, Jia Chen, Hao Wang, Chun-Chao Shi, Guang-Zhi Jin, Hui Dong & Wen-Ming Cong
Pages: 5537-5547
Published online: 08 Jul 2020
AbstractforA Novel Pathological Scoring System for Hepatic Cirrhosis with Hepatocellular Carcinoma | Full Text | References | PDF (5.7 MB) | EPUB
  • 75 Views
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Article
A Comparison Between the Online Prediction Models CancerMath and PREDICT as Prognostic Tools in Thai Breast Cancer Patients
Nuanphan Polchai, Doonyapat Sa-nguanraksa, Warapan Numprasit, Thanawat Thumrongtaradol, Eng O-charoenrat & Pornchai O-charoenrat
Pages: 5549-5559
Published online: 08 Jul 2020
AbstractforA Comparison Between the Online Prediction Models CancerMath and PREDICT as Prognostic Tools in Thai Breast Cancer Patients | Full Text | References | PDF (1,012 KB) | EPUB
  • 115 Views
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Article
Circular RNA Circ_0016760 Modulates Non-Small-Cell Lung Cancer Growth Through the miR-577/ZBTB7A Axis
Yanhong Hao, Junfeng Xi, Yancai Peng, Burong Bian, Guangjun Hao, Yunfeng Xi & Zhibin Zhang
Pages: 5561-5574
Published online: 08 Jul 2020
AbstractforCircular RNA Circ_0016760 Modulates Non-Small-Cell Lung Cancer Growth Through the miR-577/ZBTB7A Axis | Full Text | References | PDF (1.5 MB) | EPUB
  • 63 Views
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Article
LINC01535 Promotes the Development of Osteosarcoma Through Modulating miR-214-3p/KCNC4 Axis
Xiaoke Yao, Lingna Wu, Zuchao Gu & Jianhua Li
Pages: 5575-5585
Published online: 08 Jul 2020
AbstractforLINC01535 Promotes the Development of Osteosarcoma Through Modulating miR-214-3p/KCNC4 Axis | Full Text | References | PDF (6.5 MB) | EPUB
  • 62 Views
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Article
Long Intergenic Non-Protein Coding RNA 1089 Suppresses Cell Proliferation and Metastasis in Gastric Cancer by Regulating miRNA-27a-3p/Epithelial–Mesenchymal Transition (EMT) Axis
Feng Yang, Xiaoting Chen, Xiyao Li, Jianhua Chen, Yuxin Tang, Yongchang Cai, Yijun Wang, Zhiliang Chen, Libo Li, Ruiping Li & Zhenwei Deng
Pages: 5587-5596
Published online: 09 Jul 2020
AbstractforLong Intergenic Non-Protein Coding RNA 1089 Suppresses Cell Proliferation and Metastasis in Gastric Cancer by Regulating miRNA-27a-3p/Epithelial–Mesenchymal Transition (EMT) Axis | Full Text | References | PDF (6.5 MB) | EPUB
  • 69 Views
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Review

Review Article
Cancer Cachexia: Definition, Staging, and Emerging Treatments
Jun Ni & Li Zhang
Pages: 5597-5605
Published online: 09 Jul 2020
AbstractforCancer Cachexia: Definition, Staging, and Emerging Treatments | Full Text | References | PDF (322 KB) | EPUB
  • 1425 Views
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Original Research

Article
Major Hepatectomy in Elderly Patients with Large Hepatocellular Carcinoma: A Multicenter Retrospective Observational Study
Zheng-Liang Chen, Cheng-Wu Zhang, Lei Liang, Han Wu, Wan-Guang Zhang, Yong-Yi Zeng, Wei-Min Gu, Ting-Hao Chen, Jie Li, Yao-Ming Zhang, Hong Wang, Ya-Hao Zhou, Chao Li, Yong-Kang Diao, Wan Yee Lau, Meng-Chao Wu, Feng Shen, Tian Yang & Ying-Jian Liang
Pages: 5607-5618
Published online: 09 Jul 2020
AbstractforMajor Hepatectomy in Elderly Patients with Large Hepatocellular Carcinoma: A Multicenter Retrospective Observational Study | Full Text | References | PDF (2.9 MB) | EPUB
  • 83 Views
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Article
Long Intergenic Non-Protein Coding RNA 1094 Promotes Initiation and Progression of Glioblastoma by Promoting microRNA-577-Regulated Stabilization of Brain-Derived Neurotrophic Factor
Xiaoyan Dong, Xiuxin Fu, Miao Yu & Zengfen Li
Pages: 5619-5631
Published online: 09 Jul 2020
AbstractforLong Intergenic Non-Protein Coding RNA 1094 Promotes Initiation and Progression of Glioblastoma by Promoting microRNA-577-Regulated Stabilization of Brain-Derived Neurotrophic Factor | Full Text | References | PDF (7.1 MB) | EPUB
  • 69 Views
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Article
Treatment of Advanced/Metastatic Melanoma in the United States and Western Europe: Results of the CancerMPact Survey
Stephanie Hawthorne, Linda Zhao, Madelyn Hanson, Gena Kanas, Christine Davis, David Robinson, Matthew Turnure & Otavio Clark
Pages: 5633-5639
Published online: 10 Jul 2020
AbstractforTreatment of Advanced/Metastatic Melanoma in the United States and Western Europe: Results of the CancerMPact Survey | Full Text | References | PDF (372.3 KB) | EPUB
  • 102 Views
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Article
Efficacy and Safety of Anlotinib for Patients with Advanced NSCLC Who Progressed After Standard Regimens and the Preliminary Analysis of an Efficacy Predictor
Jian-De Cheng, Li-Xun Chai, Zhi-Ping Zhao, Yan-Yan Hao & Shuo Li
Pages: 5641-5650
Published online: 12 Jul 2020
AbstractforEfficacy and Safety of Anlotinib for Patients with Advanced NSCLC Who Progressed After Standard Regimens and the Preliminary Analysis of an Efficacy Predictor | Full Text | References | PDF (6.1 MB) | EPUB
  • 101 Views
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Article
Circular RNA ITCH Suppresses Cell Proliferation but Induces Apoptosis in Oral Squamous Cell Carcinoma by Regulating miR-421/PDCD4 Axis
Chunbo Hao, Kaixin Wangzhou, Zhengeng Liang, Cheng Liu, Linlin Wang, Lei Gong, Yi Tan, Conghui Li, Zhiying Lai & Guangwei Hu
Pages: 5651-5658
Published online: 12 Jul 2020
AbstractforCircular RNA ITCH Suppresses Cell Proliferation but Induces Apoptosis in Oral Squamous Cell Carcinoma by Regulating miR-421/PDCD4 Axis | Full Text | References | PDF (5.1 MB) | EPUB
  • 85 Views
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Article
The Clinical Prognostic Value of the Neutrophil-to-Lymphocyte Ratio in Brain Metastases from Non–Small Cell Lung Cancer-Harboring EGFR Mutations
Hongwei Li, Weili Wang, Xiaotang Yang, Jianhong Lian, Shuangping Zhang, Jianzhong Cao, Xiaqin Zhang, Xin Song, Sufang Jia & Ruiqi Xue
Pages: 5659-5665
Published online: 12 Jul 2020
AbstractforThe Clinical Prognostic Value of the Neutrophil-to-Lymphocyte Ratio in Brain Metastases from Non–Small Cell Lung Cancer-Harboring EGFR Mutations | Full Text | References | PDF (1.2 MB) | EPUB
  • 86 Views
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Review

Review Article
Darolutamide: An Evidenced-Based Review of Its Efficacy and Safety in the Treatment of Prostate Cancer
E David Crawford, Whitney Stanton & Divneet Mandair
Pages: 5667-5676
Published online: 13 Jul 2020
AbstractforDarolutamide: An Evidenced-Based Review of Its Efficacy and Safety in the Treatment of Prostate Cancer | Full Text | References | PDF (742.5 KB) | EPUB
  • 319 Views
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Original Research

Article
The Chinese Medicine, Shezhi Huangling Decoction, Inhibits the Growth and Metastasis of Glioma Cells via the Regulation of miR-1298-5p/TGIF1 Axis
Xiaoqian Liu, Jianfeng Ju, Qun Liu, Zongmin Zhu & Chunxia Liu
Pages: 5677-5687
Published online: 13 Jul 2020
AbstractforThe Chinese Medicine, Shezhi Huangling Decoction, Inhibits the Growth and Metastasis of Glioma Cells via the Regulation of miR-1298-5p/TGIF1 Axis | Full Text | References | PDF (4.3 MB) | EPUB
  • 103 Views
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Article
The Prognostic Factors of Preoperative Prognostic Nutritional Index and Radiological Findings of Solid Pseudopapillary Tumors of Pancreas: A Single-Center Experience of 14 Years
He Song & Ming Dong
Pages: 5689-5699
Published online: 12 Jul 2020
AbstractforThe Prognostic Factors of Preoperative Prognostic Nutritional Index and Radiological Findings of Solid Pseudopapillary Tumors of Pancreas: A Single-Center Experience of 14 Years | Full Text | References | PDF (3.6 MB) | EPUB
  • 72 Views
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Article
Identification of PDE7B as a Potential Core Gene Involved in the Metastasis of Clear Cell Renal Cell Carcinoma
Yi Sun, Junxia Zou, Wei Ouyang & Ke Chen
Pages: 5701-5712
Published online: 12 Jul 2020
AbstractforIdentification of PDE7B as a Potential Core Gene Involved in the Metastasis of Clear Cell Renal Cell Carcinoma | Full Text | References | PDF (9.7 MB) | EPUB
  • 68 Views
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Article
LncRNA PLAC2 Positively Regulates CDK2 to Promote Ovarian Carcinoma Cell Proliferation
Yuanqi He, Liqun Wei, Shihong Zhang, Haining Liu, Fang Fang & Yue Li
Pages: 5713-5720
Published online: 12 Jul 2020
AbstractforLncRNA PLAC2 Positively Regulates CDK2 to Promote Ovarian Carcinoma Cell Proliferation | Full Text | References | PDF (5.4 MB) | EPUB
  • 74 Views
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Article
A New Surgical Technique of Combination Retroperitoneal with Transperitoneal Laparoscopic Nephroureterectomy in a Single Position and Comparative Outcomes
Liming Song, Wenkuan Wang, Qinxin Zhao, Yuhong Wen, Xiaoguang Zhou, Hu Han & Xiaodong Zhang
Pages: 5721-5728
Published online: 13 Jul 2020
AbstractforA New Surgical Technique of Combination Retroperitoneal with Transperitoneal Laparoscopic Nephroureterectomy in a Single Position and Comparative Outcomes | Full Text | References | PDF (718.2 KB) | EPUB
  • 67 Views
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Article
Upregulation of METTL3 Expression Predicts Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma
Tian-Liang Xia, Shu-Mei Yan, Li Yuan & Mu-Sheng Zeng
Pages: 5729-5737
Published online: 13 Jul 2020
AbstractforUpregulation of METTL3 Expression Predicts Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (3.7 MB) | EPUB
  • 92 Views
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Retraction

Retraction
Curcumin Inhibits the Tumorigenesis of Breast Cancer by Blocking Tafazzin/Yes-Associated Protein Axis [Retraction]
Page: 5739
Published online: 14 Jul 2020
CitationforCurcumin Inhibits the Tumorigenesis of Breast Cancer by Blocking Tafazzin/Yes-Associated Protein Axis [Retraction] | Full Text | PDF (149.5 KB) | EPUB
  • 52 Views
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Original Research

Article
LncRNA LINC00520 Predicts Poor Prognosis and Promotes Progression of Lung Cancer by Inhibiting MiR-3175 Expression
Gaowei Xia, Xiaoling Li, Fuhui Chen & Zhenyu Shao
Pages: 5741-5748
Published online: 17 Jul 2020
AbstractforLncRNA LINC00520 Predicts Poor Prognosis and Promotes Progression of Lung Cancer by Inhibiting MiR-3175 Expression | Full Text | References | PDF (5 MB) | EPUB
  • 61 Views
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Article
miR-331-3p Inhibits Tumor Cell Proliferation, Metastasis, Invasion by Targeting MLLT10 in Non-Small Cell Lung Cancer
Qing-Qing Tian, Jing Xia, Xin Zhang, Bao-Qin Gao & Wei Wang
Pages: 5749-5758
Published online: 14 Jul 2020
AbstractformiR-331-3p Inhibits Tumor Cell Proliferation, Metastasis, Invasion by Targeting MLLT10 in Non-Small Cell Lung Cancer | Full Text | References | PDF (5.1 MB) | EPUB
  • 108 Views
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Article
RETRACTED ARTICLE: Modulation of MnSOD and FoxM1 Is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells
Yebei Qiu, Xiaocheng Cao, Lihua Liu, Xiaozheng Cao, Qing Yuan, Xiang Li, Yinghong Cui, Chang Xu, Chang Zou, Kaiqun Ren & Jianguo Cao
Pages: 5759-5771
Published online: 14 Jul 2020
AbstractforRETRACTED ARTICLE: Modulation of MnSOD and FoxM1 Is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells | PDF (12.3 MB)
  • 18 Views
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Article
Elevated mRNA Expression Levels of NCAPG are Associated with Poor Prognosis in Ovarian Cancer
Tao Xu, Menglu Dong, Zhi Wang, Hanning Li & Xingrui Li
Pages: 5773-5786
Published online: 14 Jul 2020
AbstractforElevated mRNA Expression Levels of NCAPG are Associated with Poor Prognosis in Ovarian Cancer | Full Text | References | PDF (14 MB) | EPUB
  • 95 Views
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Article
Retroperitoneal Laparoscopic Surgery in the Treatment of Complex Adrenal Tumors
Kai Huang, Yehua Wang, Xiao Gu, Qin Xiao & Xiangan Tu
Pages: 5787-5791
Published online: 14 Jul 2020
AbstractforRetroperitoneal Laparoscopic Surgery in the Treatment of Complex Adrenal Tumors | Full Text | References | PDF (494.5 KB) | EPUB
  • 75 Views
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Article
Predicting Individual Prognosis and Grade of Patients with Glioma Based on Preoperative Eosinophil and Neutrophil-to-Lymphocyte Ratio
Xu Zhang, Can Li, Lifei Xiao, Caibin Gao, Wei Zhao, Maolin Yang, Tao Sun & Feng Wang
Pages: 5793-5802
Published online: 14 Jul 2020
AbstractforPredicting Individual Prognosis and Grade of Patients with Glioma Based on Preoperative Eosinophil and Neutrophil-to-Lymphocyte Ratio | Full Text | References | PDF (4.5 MB) | EPUB
  • 76 Views
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Article
Metformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells
Chun Gao, Long Fang, Hui Zhang, Wei-Shuo Zhang, Xiao-Ou Li & Shi-Yu Du
Pages: 5803-5811
Published online: 14 Jul 2020
AbstractforMetformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells | Full Text | References | PDF (2.6 MB) | EPUB
  • 280 Views
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Article
Central Venous Catheter Insertion in Colorectal Cancer Patients, PICC or PC?
Lijuan Yin & Jinhua Li
Pages: 5813-5818
Published online: 14 Jul 2020
AbstractforCentral Venous Catheter Insertion in Colorectal Cancer Patients, PICC or PC? | Full Text | References | PDF (232.7 KB) | EPUB
  • 100 Views
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Review

Review Article
Refractory Metastatic Colorectal Cancer: Current Challenges and Future Prospects
Marissa Lam, Caroline Lum, Sarah Latham, Sam Tipping Smith, Hans Prenen & Eva Segelov
Pages: 5819-5830
Published online: 15 Jul 2020
AbstractforRefractory Metastatic Colorectal Cancer: Current Challenges and Future Prospects | Full Text | References | PDF (676.2 KB) | EPUB
  • 165 Views
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Original Research

Article
Tumor-Associated CD163+ M2 Macrophage Infiltration is Highly Associated with PD-L1 Expression in Cervical Cancer
Fan Guo, Yang-chun Feng, Gang Zhao, Ran Zhang, Zhen-zhen Cheng, Wei-na Kong, Hui-li Wu, Bin Xu, Xiang Lv & Xiu-min Ma
Pages: 5831-5843
Published online: 15 Jul 2020
AbstractforTumor-Associated CD163+ M2 Macrophage Infiltration is Highly Associated with PD-L1 Expression in Cervical Cancer | Full Text | References | PDF (5 MB) | EPUB
  • 108 Views
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Article
Knockdown of lncRNA MCM3AP-AS1 Attenuates Chemoresistance of Burkitt Lymphoma to Doxorubicin Treatment via Targeting the miR-15a/EIF4E Axis
Chao Guo, Ming Gong & Zhenling Li
Pages: 5845-5855
Published online: 16 Jul 2020
AbstractforKnockdown of lncRNA MCM3AP-AS1 Attenuates Chemoresistance of Burkitt Lymphoma to Doxorubicin Treatment via Targeting the miR-15a/EIF4E Axis | Full Text | References | PDF (9.1 MB) | EPUB
  • 78 Views
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Review

Review Article
Esophageal Microenvironment: From Precursor Microenvironment to Premetastatic Niche
Peng Han, Peng Cao, Shan Hu, Kangle Kong, Yu Deng, Bo Zhao & Fan Li
Pages: 5857-5879
Published online: 16 Jul 2020
AbstractforEsophageal Microenvironment: From Precursor Microenvironment to Premetastatic Niche | Full Text | References | PDF (3.2 MB) | EPUB
  • 130 Views
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Original Research

Article
Patients of Myelodysplastic Syndrome with Mild/Moderate Myelofibrosis and a Monosomal Karyotype are Independently Associated with an Adverse Prognosis: Long-Term Follow-Up Data
Na Wang, Hongzhi Xu, Qing Li, Xiaosheng Fang, Jie Liu, Xiaohui Sui, Lingyan Zhang, Yujie Jiang & Xin Wang
Pages: 5881-5891
Published online: 16 Jul 2020
AbstractforPatients of Myelodysplastic Syndrome with Mild/Moderate Myelofibrosis and a Monosomal Karyotype are Independently Associated with an Adverse Prognosis: Long-Term Follow-Up Data | Full Text | References | PDF (3.7 MB) | EPUB
  • 69 Views
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Article
Prognostic Significance of PD-L1 Expression and Its Tumor-Intrinsic Functions in Hypopharyngeal Squamous Cell Carcinoma
Peng Cui, Peihang Jing, Xiuxiu Liu & Wei Xu
Pages: 5893-5902
Published online: 17 Jul 2020
AbstractforPrognostic Significance of PD-L1 Expression and Its Tumor-Intrinsic Functions in Hypopharyngeal Squamous Cell Carcinoma | Full Text | References | PDF (6.3 MB) | EPUB
  • 92 Views
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Article
Effect of the Standardized Management of Cancer Pain on Patients with Bone Metastasis of Lung Cancer in China
Jing-Jing Jin, Tian-Tian Xu, Yan-Fang Li, Hong-Yang Wang, Dan Zhang, Pan-Pan Zhang, Li-Xin Xu, Chun-Xiu Wang, Zhu Fan, Ling Wang, Chen Liu, Shuang Wang, Hao-Tian Shi, Cai-Hong Li, Hai-Fang Zhang & Yan Huang
Pages: 5903-5907
Published online: 17 Jul 2020
AbstractforEffect of the Standardized Management of Cancer Pain on Patients with Bone Metastasis of Lung Cancer in China | Full Text | References | PDF (218.5 KB) | EPUB
  • 95 Views
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Article
Patterns of Chest Wall Recurrence and Suggestions on the Clinical Target Volume of Breast Cancer: A Retrospective Analysis of 121 Postmastectomy Patients
Lin-Wei Wang, Li Li, Hong-Yan Zhang, Yuan-Yuan Chen & Ya-Hua Zhong
Pages: 5909-5918
Published online: 17 Jul 2020
AbstractforPatterns of Chest Wall Recurrence and Suggestions on the Clinical Target Volume of Breast Cancer: A Retrospective Analysis of 121 Postmastectomy Patients | Full Text | References | PDF (3.3 MB) | EPUB
  • 123 Views
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Article
Triptonide Modulates MAPK Signaling Pathways and Exerts Anticancer Effects via ER Stress-Mediated Apoptosis Induction in Human Osteosarcoma Cells
Liyun Zheng, Shiji Fang, Junguo Hui, Vinothkumar Rajamanickam, Minjiang Chen, Qiaoyou Weng, Xulu Wu, Zhongwei Zhao & Jiansong Ji
Pages: 5919-5929
Published online: 17 Jul 2020
AbstractforTriptonide Modulates MAPK Signaling Pathways and Exerts Anticancer Effects via ER Stress-Mediated Apoptosis Induction in Human Osteosarcoma Cells | Full Text | References | PDF (9.2 MB) | EPUB
  • 75 Views
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Article
Paeonol Inhibits Cell Proliferation, Migration and Invasion and Induces Apoptosis in Hepatocellular Carcinoma by Regulating miR-21-5p/KLF6 Axis
Miaoguo Cai, Wei Shao, Huijun Yu, Ye Hong & Lili Shi
Pages: 5931-5943
Published online: 17 Jul 2020
AbstractforPaeonol Inhibits Cell Proliferation, Migration and Invasion and Induces Apoptosis in Hepatocellular Carcinoma by Regulating miR-21-5p/KLF6 Axis | Full Text | References | PDF (10.6 MB) | EPUB
  • 83 Views
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Article
circ-NRIP1 Promotes Glycolysis and Tumor Progression by Regulating miR-186-5p/MYH9 Axis in Gastric Cancer
Yanhong Liu, Yuanyuan Jiang, Lidong Xu, Chongxing Qu, Lei Zhang, Xingguo Xiao, Wenxia Chen, Kunkun Li, Qianping Liang & Huili Wu
Pages: 5945-5956
Published online: 17 Jul 2020
Abstractforcirc-NRIP1 Promotes Glycolysis and Tumor Progression by Regulating miR-186-5p/MYH9 Axis in Gastric Cancer | Full Text | References | PDF (8.9 MB) | EPUB
  • 86 Views
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Review

Review Article
Glucometabolic Reprogramming in the Hepatocellular Carcinoma Microenvironment: Cause and Effect
Huining Tian, Xiaoyu Zhu, You Lv, Yan Jiao & Guixia Wang
Pages: 5957-5974
Published online: 17 Jul 2020
AbstractforGlucometabolic Reprogramming in the Hepatocellular Carcinoma Microenvironment: Cause and Effect | Full Text | References | PDF (2.9 MB) | EPUB
  • 124 Views
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Original Research

Article
NLCIPS: Non-Small Cell Lung Cancer Immunotherapy Prognosis Score
Peng Song, Dongliang Yang, Xiaoxia Cui, Hanping Wang, Xiaoyan Si, Xiaotong Zhang & Li Zhang
Pages: 5975-5985
Published online: 17 Jul 2020
AbstractforNLCIPS: Non-Small Cell Lung Cancer Immunotherapy Prognosis Score | Full Text | References | PDF (3.6 MB) | EPUB
  • 84 Views
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Article
Application of 2011 International Federation for Cervical Pathology and Colposcopy Terminology on the Detection of Vaginal Intraepithelial Neoplasia
Qi Zhou, Feifei Zhang, Long Sui, Hongwei Zhang, Lin Lin & Yanyun Li
Pages: 5987-5995
Published online: 17 Jul 2020
AbstractforApplication of 2011 International Federation for Cervical Pathology and Colposcopy Terminology on the Detection of Vaginal Intraepithelial Neoplasia | Full Text | References | PDF (358.4 KB) | EPUB
  • 97 Views
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Article
Prognostic Impact of DHRS9 Overexpression in Pancreatic Cancer
Huang-bao Li, Jun Zhou, Fengqing Zhao, Jiayin Yu & Longsheng Xu
Pages: 5997-6006
Published online: 20 Jul 2020
AbstractforPrognostic Impact of DHRS9 Overexpression in Pancreatic Cancer | Full Text | References | PDF (3.5 MB) | EPUB
  • 88 Views
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Article
Knockdown of IKKβ Inhibits Tumor Development in a Leptomeningeal Metastasis Mouse Model and Proliferation of Lung Cancer Cells
Yakun Liu, Yuanyuan Li, Zhongyao Li, Chunyan Li, Junying He & Hui Bu
Pages: 6007-6017
Published online: 20 Jul 2020
AbstractforKnockdown of IKKβ Inhibits Tumor Development in a Leptomeningeal Metastasis Mouse Model and Proliferation of Lung Cancer Cells | Full Text | References | PDF (7.1 MB) | EPUB
  • 60 Views
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Article
Evaluation of Multiple Prognostic Factors of Hepatocellular Carcinoma with Intra-Voxel Incoherent Motions Imaging by Extracting the Histogram Metrics
Gaofeng Shi, Xue Han, Qi Wang, Yan Ding, Hui Liu, Yunfei Zhang & Yongming Dai
Pages: 6019-6031
Published online: 20 Jul 2020
Abstractfor Evaluation of Multiple Prognostic Factors of Hepatocellular Carcinoma with Intra-Voxel Incoherent Motions Imaging by Extracting the Histogram Metrics | Full Text | References | PDF (7.2 MB) | EPUB
  • 94 Views
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Article
Changes and Influential Factors of Chemotherapy Usage for Non-Small Cell Lung Cancer Patients in China: A Multicenter 10-Year (2005–2014) Retrospective Study
Pu-Yuan Xing, Shou-Zheng Wang, Ju-Fang Shi, Le Wang, Zhou-Guang Hui, Jian-Song Ren, Shang-Mei Liu, You-Lin Qiao, Min Dai & Jun-Ling Li
Pages: 6033-6044
Published online: 20 Jul 2020
AbstractforChanges and Influential Factors of Chemotherapy Usage for Non-Small Cell Lung Cancer Patients in China: A Multicenter 10-Year (2005–2014) Retrospective Study | Full Text | References | PDF (1.7 MB) | EPUB
  • 67 Views
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Article
Overexpression of lncRNA NLIPMT Inhibits Colorectal Cancer Cell Migration and Invasion by Downregulating TGF-β1
Yongkang An, Shuangxi Zhang, Jing Zhang, Qing Yin, Haitao Han, Fang Wu & Xiangan Zhang
Pages: 6045-6052
Published online: 20 Jul 2020
AbstractforOverexpression of lncRNA NLIPMT Inhibits Colorectal Cancer Cell Migration and Invasion by Downregulating TGF-β1 | Full Text | References | PDF (6.4 MB) | EPUB
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Commentary

Article Commentary
Surgical Management Strategy for Breast Cancer Patients During the COVID-19 Outbreak
Yong Liu, Jiaming Wang, Yi Tang, Rong Su & Qianwen Yang
Pages: 6053-6058
Published online: 20 Jul 2020
AbstractforSurgical Management Strategy for Breast Cancer Patients During the COVID-19 Outbreak | Full Text | References | PDF (290.3 KB) | EPUB
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Original Research

Article
RETRACTED ARTICLE: Long Non-Coding RNA AGAP2-AS1/miR-628-5p/PTN Axis Modulates Proliferation, Migration, Invasion, and Apoptosis of Glioma Cells
Yang Yan, Yiping Wang, Yuxia Liu, Tao Chen, Yaoli Zhu, Huiqing Li & Fangen Kong
Pages: 6059-6068
Published online: 20 Jul 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA AGAP2-AS1/miR-628-5p/PTN Axis Modulates Proliferation, Migration, Invasion, and Apoptosis of Glioma Cells | PDF (5.3 MB)
  • 23 Views
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Article
Elevated Platelet Count Predicts Poor Prognosis in Breast Cancer Patients with Supraclavicular Lymph Node Metastasis
Shaoqing Liu, Jing Fang, Dechuang Jiao & Zhenzhen Liu
Pages: 6069-6075
Published online: 20 Jul 2020
AbstractforElevated Platelet Count Predicts Poor Prognosis in Breast Cancer Patients with Supraclavicular Lymph Node Metastasis | Full Text | References | PDF (1.1 MB) | EPUB
  • 117 Views
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Article
Obesity and Waist Circumference are Possible Risk Factors for Thyroid Cancer: Correlation with Different Ultrasonography Criteria
Marwa S Eissa, Mona S Abdellateif, Yasmine F Elesawy, Sabry Shaarawy & Ula M Al-Jarhi
Pages: 6077-6089
Published online: 21 Jul 2020
AbstractforObesity and Waist Circumference are Possible Risk Factors for Thyroid Cancer: Correlation with Different Ultrasonography Criteria | Full Text | References | PDF (4.7 MB) | EPUB
  • 91 Views
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Article
Long Non-Coding RNA NEAT1 Promotes the Proliferation, Migration, and Metastasis of Human Breast-Cancer Cells by Inhibiting miR-146b-5p Expression
Songming Li, Junwen Hao, Yun Hong, Junhao Mai & Weijun Huang
Pages: 6091-6101
Published online: 21 Jul 2020
AbstractforLong Non-Coding RNA NEAT1 Promotes the Proliferation, Migration, and Metastasis of Human Breast-Cancer Cells by Inhibiting miR-146b-5p Expression | Full Text | References | PDF (5.9 MB) | EPUB
  • 126 Views
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Review

Review Article
Emerging Roles of Long Noncoding RNA Regulator of Reprogramming in Cancer Treatment
Di-Er Sun & Shu-Yuan Ye
Pages: 6103-6112
Published online: 21 Jul 2020
AbstractforEmerging Roles of Long Noncoding RNA Regulator of Reprogramming in Cancer Treatment | Full Text | References | PDF (1.1 MB) | EPUB
  • 82 Views
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Original Research

Article
ONECUT2 Accelerates Tumor Proliferation Through Activating ROCK1 Expression in Gastric Cancer
Jie Chen, Jinggui Chen, Bo Sun, Jianghong Wu & Chunyan Du
Pages: 6113-6121
Published online: 21 Jul 2020
AbstractforONECUT2 Accelerates Tumor Proliferation Through Activating ROCK1 Expression in Gastric Cancer | Full Text | References | PDF (5.6 MB) | EPUB
  • 115 Views
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Review

Review Article
PARP Inhibitors in Endometrial Cancer: Current Status and Perspectives
Lucia Musacchio, Giuseppe Caruso, Carmela Pisano, Sabrina Chiara Cecere, Marilena Di Napoli, Laura Attademo, Rosa Tambaro, Daniela Russo, Daniela Califano, Innocenza Palaia, Ludovico Muzii, Pierluigi Benedetti Panici & Sandro Pignata
Pages: 6123-6135
Published online: 22 Jul 2020
AbstractforPARP Inhibitors in Endometrial Cancer: Current Status and Perspectives | Full Text | References | PDF (1.5 MB) | EPUB
  • 278 Views
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Original Research

Article
MiR-887-3p Negatively Regulates STARD13 and Promotes Pancreatic Cancer Progression
Xiaobo Xu & Shusen Zheng
Pages: 6137-6147
Published online: 22 Jul 2020
AbstractforMiR-887-3p Negatively Regulates STARD13 and Promotes Pancreatic Cancer Progression | Full Text | References | PDF (8.2 MB) | EPUB
  • 76 Views
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Article
Aberrant Expression of Citrate Synthase is Linked to Disease Progression and Clinical Outcome in Prostate Cancer
Zhiduan Cai, Yulin Deng, Jianheng Ye, Yangjia Zhuo, Zezhen Liu, Yingke Liang, Hui Zhang, Xuejin Zhu, Yong Luo, Yuanfa Feng, Ren Liu, Guo Chen, Yongding Wu, Zhaodong Han, Yuxiang Liang, Funeng Jiang & Weide Zhong
Pages: 6149-6163
Published online: 22 Jul 2020
AbstractforAberrant Expression of Citrate Synthase is Linked to Disease Progression and Clinical Outcome in Prostate Cancer | Full Text | References | PDF (11.8 MB) | EPUB
  • 149 Views
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Article
RETRACTED ARTICLE: MiR-145 Regulates the Chemoresistance of Hepatic Carcinoma Cells Against 5-Fluorouracil by Targeting Toll-Like Receptor 4
Rui-Peng Zheng, Dong-Kai Ma, Zhuo Li & Hai-Feng Zhang
Pages: 6165-6175
Published online: 22 Jul 2020
AbstractforRETRACTED ARTICLE: MiR-145 Regulates the Chemoresistance of Hepatic Carcinoma Cells Against 5-Fluorouracil by Targeting Toll-Like Receptor 4 | PDF (5.8 MB)
  • 40 Views
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Article
The Efficacy and Safety of Apatinib in Refractory/Relapse Advanced Pediatric Solid Tumor: A Retrospective Study
Feifei Sun, Suying Lu, Zijun Zhen, Jia Zhu, Juan Wang, Junting Huang, Yu Zhang, Hui Li, Ruiqing Cai, Meiling Liu, Liuhong Wu, Xiaofei Sun & Yizhuo Zhang
Pages: 6177-6185
Published online: 22 Jul 2020
AbstractforThe Efficacy and Safety of Apatinib in Refractory/Relapse Advanced Pediatric Solid Tumor: A Retrospective Study | Full Text | References | PDF (2 MB) | EPUB
  • 108 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA FGD5-AS1 Promotes Glioma Cell Proliferation, Migration and Invasion by Regulating wnt/β-Catenin Pathway
Jun Bo Zhao, Jun Feng Xue, Wu Zhong Zhang, Yong Lu Ren & Dong Ming Yan
Pages: 6187-6193
Published online: 23 Jul 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA FGD5-AS1 Promotes Glioma Cell Proliferation, Migration and Invasion by Regulating wnt/β-Catenin Pathway | PDF (2.8 MB)
  • 39 Views
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Article
The Natural Product Fucoidan Inhibits Proliferation and Induces Apoptosis of Human Ovarian Cancer Cells: Focus on the PI3K/Akt Signaling Pathway
Shuhan Liu, Jing Yang, Xudong Peng, Jingjing Li & Cunjing Zhu
Pages: 6195-6207
Published online: 23 Jul 2020
AbstractforThe Natural Product Fucoidan Inhibits Proliferation and Induces Apoptosis of Human Ovarian Cancer Cells: Focus on the PI3K/Akt Signaling Pathway | Full Text | References | PDF (6.2 MB) | EPUB
  • 168 Views
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Article
Adherence to Hepatocellular Carcinoma Surveillance and Perceived Barriers Among High-Risk Chronic Liver Disease Patients in Yunnan, China
Jingyi Dai, Jun Zhao, Yingrong Du, Lin Zhuang, Edward B McNeil & Virasakdi Chongsuvivatwong
Pages: 6209-6220
Published online: 23 Jul 2020
AbstractforAdherence to Hepatocellular Carcinoma Surveillance and Perceived Barriers Among High-Risk Chronic Liver Disease Patients in Yunnan, China | Full Text | References | PDF (3 MB) | EPUB
  • 80 Views
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Article
Secular Trend of Cancer Death and Incidence in 29 Cancer Groups in China, 1990–2017: A Joinpoint and Age–Period–Cohort Analysis
Xiaoxue Liu, Maigeng Zhou, Fang Wang, Sumaira Mubarik, Yafeng Wang, Runtang Meng, Fang Shi, Haoyu Wen & Chuanhua Yu
Pages: 6221-6238
Published online: 23 Jul 2020
AbstractforSecular Trend of Cancer Death and Incidence in 29 Cancer Groups in China, 1990–2017: A Joinpoint and Age–Period–Cohort Analysis | Full Text | References | PDF (15 MB) | EPUB
  • 144 Views
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Corrigendum

Correction
Prognostic Factors and Local Treatment Modalities of Small-Cell Carcinoma of the Cervix: An Analysis According to the International Federation of Gynecology and Obstetrics Stage [Corrigendum]
Page: 6239
Published online: 23 Jul 2020
CitationforPrognostic Factors and Local Treatment Modalities of Small-Cell Carcinoma of the Cervix: An Analysis According to the International Federation of Gynecology and Obstetrics Stage [Corrigendum] | Full Text | PDF (149 KB) | EPUB
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Original Research

Article
MiR-27a-3p Targeting GSK3β Promotes Triple-Negative Breast Cancer Proliferation and Migration Through Wnt/β-Catenin Pathway
Ruizhen Wu, Bingqing Zhao, Xunxin Ren, Shiheng Wu, Mingzao Liu, Zipeng Wang & Wei Liu
Pages: 6241-6249
Published online: 24 Jul 2020
AbstractforMiR-27a-3p Targeting GSK3β Promotes Triple-Negative Breast Cancer Proliferation and Migration Through Wnt/β-Catenin Pathway | Full Text | References | PDF (4.4 MB) | EPUB
  • 156 Views
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Article
Identification of a Novel Prognostic Classification Model in Epithelial Ovarian Cancer by Cluster Analysis
Kelie Chen, Yuequn Niu, Shengchao Wang, Zhiqin Fu, Hui Lin, Jiaoying Lu, Xinyi Meng, Bowen Yang, Honghe Zhang, Yihua Wu, Dajing Xia & Weiguo Lu
Pages: 6251-6259
Published online: 24 Jul 2020
AbstractforIdentification of a Novel Prognostic Classification Model in Epithelial Ovarian Cancer by Cluster Analysis | Full Text | References | PDF (3.3 MB) | EPUB
  • 78 Views
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Article
High Level of IL-10 in Cerebrospinal Fluid is Specific for Diagnosis of Primary Central Nervous System Lymphoma
Jie Shao, Kun Chen, Qing Li, Jingjing Ma, Yan Ma, Zhiguang Lin, Hui Kang & Bobin Chen
Pages: 6261-6268
Published online: 24 Jul 2020
AbstractforHigh Level of IL-10 in Cerebrospinal Fluid is Specific for Diagnosis of Primary Central Nervous System Lymphoma | Full Text | References | PDF (973 KB) | EPUB
  • 97 Views
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Article
FOXCUT Promotes the Proliferation and Invasion by Activating FOXC1/PI3K/AKT Pathway in Colorectal Cancer
Xiaojie Zhang, Shanyong Yi, Guochen Xing, Huili Wu, Ying Zhu, Xiaodan Guo & Lei Zhang
Pages: 6269-6278
Published online: 24 Jul 2020
AbstractforFOXCUT Promotes the Proliferation and Invasion by Activating FOXC1/PI3K/AKT Pathway in Colorectal Cancer | Full Text | References | PDF (4.2 MB) | EPUB
  • 68 Views
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Article
Puerarin Enhances the Anti-Tumor Effect of Cisplatin on Drug-Resistant A549 Cancer in vivo and in vitro Through Activation of the Wnt Signaling Pathway
Ping Huang & Shi-Xia Du
Pages: 6279-6289
Published online: 24 Jul 2020
AbstractforPuerarin Enhances the Anti-Tumor Effect of Cisplatin on Drug-Resistant A549 Cancer in vivo and in vitro Through Activation of the Wnt Signaling Pathway | Full Text | References | PDF (4.9 MB) | EPUB
  • 78 Views
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Article
A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles from Culture Supernatant of Human Ovarian Cancer Cell Line A2780 and Body Fluids of High-Grade Serous Carcinoma Patients
Ruili Jiao, Shipeng Sun, Xiaoqiong Gao, Ran Cui, Guangming Cao, Huali Wei, Shuzhen Wang, Zhenyu Zhang & Huimin Bai
Pages: 6291-6301
Published online: 24 Jul 2020
AbstractforA Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles from Culture Supernatant of Human Ovarian Cancer Cell Line A2780 and Body Fluids of High-Grade Serous Carcinoma Patients | Full Text | References | PDF (4.8 MB) | EPUB
  • 105 Views
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Article
miR-143-3p Targets lncRNA PSMG3-AS1 to Inhibit the Proliferation of Hepatocellular Carcinoma Cells
Jianlin Zhang, Jin Huang, Weidong Chen, Zhiwan Hu & Xingyu Wang
Pages: 6303-6309
Published online: 27 Jul 2020
AbstractformiR-143-3p Targets lncRNA PSMG3-AS1 to Inhibit the Proliferation of Hepatocellular Carcinoma Cells | Full Text | References | PDF (4.5 MB) | EPUB
  • 86 Views
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Case Report

Case Report
Combining PD-1 Inhibitor Nivolumab with Radiotherapy Successfully Treated a Patient with Refractory Primary Mediastinal Large B-Cell Lymphoma: A Case Report and Literature Review
Zheng Yan, Zhi-Hua Yao, Shu-Na Yao, Qing-Xin Xia, Hai-Ying Wang, Jun-Feng Chu, Ming Song, Shuang Zhao & Yan-Yan Liu
Pages: 6311-6316
Published online: 27 Jul 2020
AbstractforCombining PD-1 Inhibitor Nivolumab with Radiotherapy Successfully Treated a Patient with Refractory Primary Mediastinal Large B-Cell Lymphoma: A Case Report and Literature Review | Full Text | References | PDF (1.8 MB) | EPUB
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Original Research

Article
Long-Noncoding RNA FGD5-AS1 Enhances the Viability, Migration, and Invasion of Glioblastoma Cells by Regulating the miR-103a-3p/TPD52 Axis
Daoqing Su, Zhengang Ji, Pengfei Xue, Shengfu Guo, Qingbin Jia & Hanyu Sun
Pages: 6317-6329
Published online: 27 Jul 2020
AbstractforLong-Noncoding RNA FGD5-AS1 Enhances the Viability, Migration, and Invasion of Glioblastoma Cells by Regulating the miR-103a-3p/TPD52 Axis | Full Text | References | PDF (9.4 MB) | EPUB
  • 69 Views
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Article
Predictors of Precancerous Cervical Lesions Among Women Screened for Cervical Cancer in Bahir Dar Town, Ethiopia: A Case–Control Study
Jerusalem Azene Alamiraw, Abiyot Wolie Asres & Getachew Asmare Adella
Pages: 6331-6339
Published online: 27 Jul 2020
AbstractforPredictors of Precancerous Cervical Lesions Among Women Screened for Cervical Cancer in Bahir Dar Town, Ethiopia: A Case–Control Study | Full Text | References | PDF (295.2 KB) | EPUB
  • 253 Views
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Article
A Conceptual Model of an Oncology Information System
Azadeh Yazdanian, Haleh Ayatollahi & Azin Nahvijou
Pages: 6341-6352
Published online: 27 Jul 2020
AbstractforA Conceptual Model of an Oncology Information System | Full Text | References | PDF (4.2 MB) | EPUB
  • 198 Views
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Article
Prognostic Significance of Rab27A and Rab27B Expression in Esophageal Squamous Cell Cancer
Fengqiang Yu, Weihan Wu, Mingqiang Liang, Yu Huang & Chun Chen
Pages: 6353-6361
Published online: 27 Jul 2020
AbstractforPrognostic Significance of Rab27A and Rab27B Expression in Esophageal Squamous Cell Cancer | Full Text | References | PDF (4.2 MB) | EPUB
  • 67 Views
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Article
Elevated Pulmonary Artery Systolic Pressure is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer
Xue Yang, Lina Wang, Lianjun Lin & Xinmin Liu
Pages: 6363-6371
Published online: 27 Jul 2020
AbstractforElevated Pulmonary Artery Systolic Pressure is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer | Full Text | References | PDF (1 MB) | EPUB
  • 79 Views
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Article
The Clinical Relevance and Function of Krüppel-Like Factor 16 in Breast Cancer
Soyeon Bang, Junhong Li, Meiqin Zhang, Renjie Cui, Xingwen Wu, Zhaochen Xin, Duan Ma, Jin Zhang & Hongwei Zhang
Pages: 6373-6383
Published online: 27 Jul 2020
AbstractforThe Clinical Relevance and Function of Krüppel-Like Factor 16 in Breast Cancer | Full Text | References | PDF (7.3 MB) | EPUB
  • 100 Views
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Article
PD-L1 in Lung Adenocarcinoma: Insights into the Role of 18F-FDG PET/CT
Yan Cui, Xuena Li, Bulin Du, Yao Diao & Yaming Li
Pages: 6385-6395
Published online: 27 Jul 2020
AbstractforPD-L1 in Lung Adenocarcinoma: Insights into the Role of 18F-FDG PET/CT | Full Text | References | PDF (5 MB) | EPUB
  • 60 Views
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Article
Silencing lncRNA AFAP1-AS1 Inhibits the Progression of Esophageal Squamous Cell Carcinoma Cells via Regulating the miR-498/VEGFA Axis
Wenhao Shen, Lei Yu, Aihua Cong, Song Yang, Peng Wang, Gaohua Han, Bin Gu & Wei Zhang
Pages: 6397-6409
Published online: 29 Jul 2020
AbstractforSilencing lncRNA AFAP1-AS1 Inhibits the Progression of Esophageal Squamous Cell Carcinoma Cells via Regulating the miR-498/VEGFA Axis | Full Text | References | PDF (30.3 MB) | EPUB
  • 53 Views
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Article
RETRACTED ARTICLE: Regulation of RUNX3 Expression by DNA Methylation in Prostate Cancer
Xin Yang, Shumei Wang & Alimu Reheman
Pages: 6411-6420
Published online: 27 Jul 2020
AbstractforRETRACTED ARTICLE: Regulation of RUNX3 Expression by DNA Methylation in Prostate Cancer | PDF (4.5 MB)
  • 22 Views
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Article
Assessment of Clinical Stage IA Lung Adenocarcinoma with pN1/N2 Metastasis Using CT Quantitative Texture Analysis
Haixu Zhu, Yanyan Xu, Nanxue Liang, Hongliang Sun, Zhenguo Huang, Sheng Xie & Wu Wang
Pages: 6421-6430
Published online: 28 Jul 2020
AbstractforAssessment of Clinical Stage IA Lung Adenocarcinoma with pN1/N2 Metastasis Using CT Quantitative Texture Analysis | Full Text | References | PDF (13.3 MB) | EPUB
  • 65 Views
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Article
Risk Stratification Based on Metastatic Pelvic Lymph Node Status in Stage IIIC1p Cervical Cancer
Anyang Li, Luhui Wang, Qi Jiang, Wenlie Wu, Baoyou Huang & Haiyan Zhu
Pages: 6431-6439
Published online: 28 Jul 2020
AbstractforRisk Stratification Based on Metastatic Pelvic Lymph Node Status in Stage IIIC1p Cervical Cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 65 Views
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Article
Circ_0000885 Enhances Osteosarcoma Progression by Increasing FGFR1 Expression via Sponging MiR-1294
Yinxian Chen, Sicheng Zhang, Chuanqing Bai, Zhiye Guan & Wenjian Chen
Pages: 6441-6452
Published online: 28 Jul 2020
AbstractforCirc_0000885 Enhances Osteosarcoma Progression by Increasing FGFR1 Expression via Sponging MiR-1294 | Full Text | References | PDF (7.7 MB) | EPUB
  • 82 Views
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Article
Diagnostic and Predictive Values of 18F-FDG PET/CT Metabolic Parameters in EGFR-Mutated Advanced Lung Adenocarcinoma
Il Ki Hong, Jeong Mi Lee, In Kyoung Hwang, Seung Sook Paik, Chanwoo Kim & Seung Hyeun Lee
Pages: 6453-6465
Published online: 28 Jul 2020
AbstractforDiagnostic and Predictive Values of 18F-FDG PET/CT Metabolic Parameters in EGFR-Mutated Advanced Lung Adenocarcinoma | Full Text | References | PDF (11.8 MB) | EPUB
  • 74 Views
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Review

Review Article
Treatment of Gastric Cancer Patients During COVID-19 Pandemic: The West is More Vulnerable
Wojciech Piotr Polkowski, Katarzyna Sędłak & Karol Rawicz-Pruszyński
Pages: 6467-6476
Published online: 30 Jul 2020
AbstractforTreatment of Gastric Cancer Patients During COVID-19 Pandemic: The West is More Vulnerable | Full Text | References | PDF (1.3 MB) | EPUB
  • 81 Views
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Original Research

Article
SRF Potentiates Colon Cancer Metastasis and Progression in a microRNA-214/PTK6-Dependent Manner
Tao Li, Yingchun Wan, Ziyuan Su, Jiayu Li, Minna Han & Changyu Zhou
Pages: 6477-6491
Published online: 28 Jul 2020
AbstractforSRF Potentiates Colon Cancer Metastasis and Progression in a microRNA-214/PTK6-Dependent Manner | Full Text | References | PDF (13.1 MB) | EPUB
  • 87 Views
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Review

Review Article
A Review About Pembrolizumab in First-Line Treatment of Advanced NSCLC: Focus on KEYNOTE Studies
Jialin Qu, Li Wang, Man Jiang, Deze Zhao, Yuyang Wang, Feng Zhang, Jing Li & Xiaochun Zhang
Pages: 6493-6509
Published online: 28 Jul 2020
AbstractforA Review About Pembrolizumab in First-Line Treatment of Advanced NSCLC: Focus on KEYNOTE Studies | Full Text | References | PDF (11.1 MB) | EPUB
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Original Research

Article
LINC01094 Down-Regulates miR-330-3p and Enhances the Expression of MSI1 to Promote the Progression of Glioma
Bin Zhu, Wei Liu, Hongliang Liu, Qiang Xu & Wei Xu
Pages: 6511-6521
Published online: 28 Jul 2020
AbstractforLINC01094 Down-Regulates miR-330-3p and Enhances the Expression of MSI1 to Promote the Progression of Glioma | Full Text | References | PDF (6.6 MB) | EPUB
  • 66 Views
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Article
Value of Visceral Fat Area in the Preoperative Discrimination of Peritoneal Metastasis from Gastric Cancer in Patients with Different Body Mass Index: A Prospective Study
He Huang, Xinxin Yang, Jing Sun, Ce Zhu, Xiang Wang, Yunpeng Zeng, Jingxuan Xu, Chenchen Mao & Xian Shen
Pages: 6523-6532
Published online: 28 Jul 2020
AbstractforValue of Visceral Fat Area in the Preoperative Discrimination of Peritoneal Metastasis from Gastric Cancer in Patients with Different Body Mass Index: A Prospective Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 67 Views
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Article
The Accuracy of Three-Dimensional Planned Bone Tumor Resection Using Patient-Specific Instrument
Daniel A Müller, Yannik Stutz, Lazaros Vlachopoulos, Mazda Farshad & Philipp Fürnstahl
Pages: 6533-6540
Published online: 29 Jul 2020
AbstractforThe Accuracy of Three-Dimensional Planned Bone Tumor Resection Using Patient-Specific Instrument | Full Text | References | PDF (2 MB) | EPUB
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Article
Impact of Extracapsular Lymph Node Involving the Esophagus in Esophageal Perforation During and After Radiotherapy: A Propensity Score-Matched Analysis
Chen Chen, Xiaobin Fu, Yaqing Dai, Qiwei Yao, Liyuan Huang & Jiancheng Li
Pages: 6541-6551
Published online: 29 Jul 2020
AbstractforImpact of Extracapsular Lymph Node Involving the Esophagus in Esophageal Perforation During and After Radiotherapy: A Propensity Score-Matched Analysis | Full Text | References | PDF (1.9 MB) | EPUB
  • 69 Views
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Article
LncRNA MALAT1 Promotes the Proliferation, Migration, and Invasion of Melanoma Cells by Downregulating miR-23a
Pan Wang, Liu Hu, Guili Fu, Jingjing Lu, Yuanquan Zheng, Ying Li & Lin Jia
Pages: 6553-6562
Published online: 29 Jul 2020
AbstractforLncRNA MALAT1 Promotes the Proliferation, Migration, and Invasion of Melanoma Cells by Downregulating miR-23a | Full Text | References | PDF (7.2 MB) | EPUB
  • 77 Views
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Article
MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy
Wei Li, Xia Qin, Bin Wang, Ge Xu, Jun Zhang, Xuejun Jiang, Chengzhi Chen, Feng Qiu & Zhen Zou
Pages: 6563-6573
Published online: 29 Jul 2020
AbstractforMiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy | Full Text | References | PDF (2.8 MB) | EPUB
  • 87 Views
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Article
Efficacy of Olanzapine-Triple Antiemetic Regimen in Patients with Gastrointestinal Tumor and High Risk of Chemotherapy-Induced Nausea and Vomiting Receiving Moderately Emetogenic Chemotherapy: A Retrospective Study
Xuan Wu, Jingxun Wu, Gangling Tong, Boran Cheng, Minhua Chen, Shaokang Yu, Lirui He, Zhu Li & Shubin Wang
Pages: 6575-6583
Published online: 29 Jul 2020
AbstractforEfficacy of Olanzapine-Triple Antiemetic Regimen in Patients with Gastrointestinal Tumor and High Risk of Chemotherapy-Induced Nausea and Vomiting Receiving Moderately Emetogenic Chemotherapy: A Retrospective Study | Full Text | References | PDF (996.7 KB) | EPUB
  • 102 Views
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Article
LncRNA HEIH Confers Cell Sorafenib Resistance in Hepatocellular Carcinoma by Regulating miR-98-5p/PI3K/AKT Pathway
Qian Shen, Shenhua Jiang, Mingyun Wu, Lei Zhang, Xue Su & Ding Zhao
Pages: 6585-6595
Published online: 29 Jul 2020
AbstractforLncRNA HEIH Confers Cell Sorafenib Resistance in Hepatocellular Carcinoma by Regulating miR-98-5p/PI3K/AKT Pathway | Full Text | References | PDF (8.1 MB) | EPUB
  • 74 Views
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Article
Prognosis Factors of Young Patients Undergoing Curative Resection for Hepatitis B Virus-Related Hepatocellular Carcinoma: A Multicenter Study
Jianxing Zeng, Kongying Lin, Huocheng Liu, Yao Huang, Pengfei Guo, Yongyi Zeng, Jinhua Zeng & Jingfeng Liu
Pages: 6597-6606
Published online: 30 Jul 2020
AbstractforPrognosis Factors of Young Patients Undergoing Curative Resection for Hepatitis B Virus-Related Hepatocellular Carcinoma: A Multicenter Study | Full Text | References | PDF (23.7 MB) | EPUB
  • 69 Views
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Article
Antiproliferative Effects of Telotristat Ethyl in Patients with Neuroendocrine Tumors: The TELEACE Real-World Chart Review Study
Michael A Morse, Eric Liu, Vijay N Joish, Lynn Huynh, Mu Cheng, Mei Sheng Duh, Kiernan Seth, Pablo Lapuerta & David C Metz
Pages: 6607-6614
Published online: 30 Jul 2020
AbstractforAntiproliferative Effects of Telotristat Ethyl in Patients with Neuroendocrine Tumors: The TELEACE Real-World Chart Review Study | Full Text | References | PDF (3 MB) | EPUB
  • 84 Views
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Review

Review Article
Optimal Care for Patients with Anaplastic Lymphoma Kinase (ALK)–Positive Non–Small Cell Lung Cancer: A Review on the Role and Utility of ALK Inhibitors
Abhay Singh & Hongbin Chen
Pages: 6615-6628
Published online: 30 Jul 2020
AbstractforOptimal Care for Patients with Anaplastic Lymphoma Kinase (ALK)–Positive Non–Small Cell Lung Cancer: A Review on the Role and Utility of ALK Inhibitors | Full Text | References | PDF (407 KB) | EPUB
  • 113 Views
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Original Research

Article
RETRACTED ARTICLE: Long Non-Coding RNA BLACAT1 Promotes the Tumorigenesis of Gastric Cancer by Sponging microRNA-149-5p and Targeting KIF2A
Zhengkun Wang, Xichun Liu, Xiaolei Liu & Dongguang Niu
Pages: 6629-6640
Published online: 30 Jul 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA BLACAT1 Promotes the Tumorigenesis of Gastric Cancer by Sponging microRNA-149-5p and Targeting KIF2A | PDF (53.6 MB)
  • 12 Views
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Article
Comparison of Docetaxel + Oxaliplatin + S-1 vs Oxalipatin + S-1 as Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer: A Propensity Score Matched Analysis
Xin Zhang, Hejing Huang, Ziran Wei, Zhenxin Zhu, Dejun Yang, Hongbing Fu, Jiapeng Xu, Zunqi Hu, Yu Zhang, Qing You, Xin Huang, Ronglin Yan, Weimin Wang & Qingping Cai
Pages: 6641-6653
Published online: 30 Jul 2020
AbstractforComparison of Docetaxel + Oxaliplatin + S-1 vs Oxalipatin + S-1 as Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer: A Propensity Score Matched Analysis | Full Text | References | PDF (3.5 MB) | EPUB
  • 77 Views
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Article
Targeting EGFR Enriches Stem Cell-Like Properties in Salivary Adenoid Cystic Carcinoma by Activating the Notch1 Pathway
Yang Wang, Yong Han, Shengming Xu, Ling Zhang, Xiangkai Zhang, Jiong Deng, Weimin Ye & Shuli Liu
Pages: 6655-6663
Published online: 31 Jul 2020
AbstractforTargeting EGFR Enriches Stem Cell-Like Properties in Salivary Adenoid Cystic Carcinoma by Activating the Notch1 Pathway | Full Text | References | PDF (34.2 MB) | EPUB
  • 71 Views
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Article
Analyses of DNA Methylation Involved in the Activation of Nuclear Karyopherin Alpha 2 Leading to Identify the Progression and Prognostic Significance Across Human Breast Cancer
Xiangrong Cui, Xuan Jing, Xueqing Wu, Jing Xu, Zhuang Liu, Kai Huo & Hongwei Wang
Pages: 6665-6677
Published online: 03 Aug 2020
AbstractforAnalyses of DNA Methylation Involved in the Activation of Nuclear Karyopherin Alpha 2 Leading to Identify the Progression and Prognostic Significance Across Human Breast Cancer | Full Text | References | PDF (44.6 MB) | EPUB
  • 77 Views
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Article
miR-31-5p Regulates 14-3-3 ɛ to Inhibit Prostate Cancer 22RV1 Cell Survival and Proliferation via PI3K/AKT/Bcl-2 Signaling Pathway
Jiafu Zhao, Houqiang Xu, Zhiqiang Duan, Xiang Chen, Zheng Ao, Yinglian Chen, Yong Ruan & Mengmeng Ni
Pages: 6679-6694
Published online: 31 Jul 2020
AbstractformiR-31-5p Regulates 14-3-3 ɛ to Inhibit Prostate Cancer 22RV1 Cell Survival and Proliferation via PI3K/AKT/Bcl-2 Signaling Pathway | Full Text | References | PDF (9.2 MB) | EPUB
  • 102 Views
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Review

Review Article
Research Progress and Existing Problems for Abscopal Effect
Di Wang, Xia Zhang, Yajie Gao, Xiaonan Cui, Yanqin Yang, Weifeng Mao, Minghuan Li, Bin Zhang & Jinming Yu
Pages: 6695-6706
Published online: 03 Aug 2020
AbstractforResearch Progress and Existing Problems for Abscopal Effect | Full Text | References | PDF (1.5 MB) | EPUB
  • 155 Views
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Original Research

Article
OIP5-AS1/miR-137/ZNF217 Axis Promotes Malignant Behaviors in Epithelial Ovarian Cancer
Linlin Guo, Jiabao Chen, Dong Liu & Lili Liu
Pages: 6707-6717
Published online: 03 Aug 2020
AbstractforOIP5-AS1/miR-137/ZNF217 Axis Promotes Malignant Behaviors in Epithelial Ovarian Cancer | Full Text | References | PDF (7.8 MB) | EPUB
  • 93 Views
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Article
Association of Preoperative Neutrophil/Lymphocyte Ratio with Clinical Outcomes in Dedifferentiated Chondrosarcoma Patients
Chenglei Liu, Yue Xing, Qiong Jiao, Qingcheng Yang, Wenbin Yu, Yuncheng Li, Xiaofeng Tao & Weiwu Yao
Pages: 6719-6726
Published online: 03 Aug 2020
AbstractforAssociation of Preoperative Neutrophil/Lymphocyte Ratio with Clinical Outcomes in Dedifferentiated Chondrosarcoma Patients | Full Text | References | PDF (2.2 MB) | EPUB
  • 64 Views
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Article
Absolute Counts of Peripheral Lymphocyte Subsets Correlate with the Progression-Free Survival and Metastatic Status of Pancreatic Neuroendocrine Tumour Patients
Yitao Gong, Zhiyao Fan, Guopei Luo, Qiuyi Huang, Yunzhen Qian, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu & Chen Liu
Pages: 6727-6737
Published online: 03 Aug 2020
AbstractforAbsolute Counts of Peripheral Lymphocyte Subsets Correlate with the Progression-Free Survival and Metastatic Status of Pancreatic Neuroendocrine Tumour Patients | Full Text | References | PDF (3 MB) | EPUB
  • 82 Views
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Article
Risk Factors for Urethral Recurrence in Men After Radical Cystectomy with Orthotopic Urinary Diversion for Urothelial Carcinoma: A Retrospective Cohort Study
Dong Hyeon Lee & Wan Song
Pages: 6739-6746
Published online: 03 Aug 2020
AbstractforRisk Factors for Urethral Recurrence in Men After Radical Cystectomy with Orthotopic Urinary Diversion for Urothelial Carcinoma: A Retrospective Cohort Study | Full Text | References | PDF (2.1 MB) | EPUB
  • 66 Views
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Article
Evaluation of p16 in Epithelial Ovarian Cancer for a 10-Year Study in Northeast China: Significance of HPV in Correlation with PD-L1 Expression
Xinxin Yang, Qi You, Guodong Yao, Jingshu Geng, Rong Ma & Hongxue Meng
Pages: 6747-6753
Published online: 03 Aug 2020
AbstractforEvaluation of p16 in Epithelial Ovarian Cancer for a 10-Year Study in Northeast China: Significance of HPV in Correlation with PD-L1 Expression | Full Text | References | PDF (10.9 MB) | EPUB
  • 94 Views
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Article
Influence of Programmed Death Ligand-1-Gene Polymorphism rs822336 on the Prognosis and Safety of Postoperative Patients with NSCLC Who Received Platinum-Based Adjuvant Chemotherapy
Ming Zhao, Jing Zhang, Siyu Chen, Yuqi Wang & Qing Tian
Pages: 6755-6766
Published online: 04 Aug 2020
AbstractforInfluence of Programmed Death Ligand-1-Gene Polymorphism rs822336 on the Prognosis and Safety of Postoperative Patients with NSCLC Who Received Platinum-Based Adjuvant Chemotherapy | Full Text | References | PDF (4.1 MB) | EPUB
  • 53 Views
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Article
Estrogen-Induced Stromal FGF18 Promotes Proliferation and Invasion of Endometrial Carcinoma Cells Through ERK and Akt Signaling
Jian Wu, Xiang Tao, Hong Zhang, Xiang-Hua Yi & Yin-Hua Yu
Pages: 6767-6777
Published online: 04 Aug 2020
AbstractforEstrogen-Induced Stromal FGF18 Promotes Proliferation and Invasion of Endometrial Carcinoma Cells Through ERK and Akt Signaling | Full Text | References | PDF (6.2 MB) | EPUB
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Article
RETRACTED ARTICLE: Long Non-Coding RNA LINC00491 Contributes to the Malignancy of Non-Small-Cell Lung Cancer via Competitively Binding to microRNA-324-5p and Thereby Increasing Specificity Protein 1 Expression
Xiaoning Zhang, Xia Zhao, Yanqing Wang & Liqun Xing
Pages: 6779-6793
Published online: 06 Aug 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA LINC00491 Contributes to the Malignancy of Non-Small-Cell Lung Cancer via Competitively Binding to microRNA-324-5p and Thereby Increasing Specificity Protein 1 Expression | PDF (67.1 MB)
  • 10 Views
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Article
circ_0136666 Facilitates the Progression of Colorectal Cancer via miR-383/CREB1 Axis
Yuhui Li, Hongliang Zang, Xue Zhang & Guomin Huang
Pages: 6795-6806
Published online: 04 Aug 2020
Abstractforcirc_0136666 Facilitates the Progression of Colorectal Cancer via miR-383/CREB1 Axis | Full Text | References | PDF (12.7 MB) | EPUB
  • 75 Views
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Article
LncRNA CDKN2B-AS1 Promotes Cell Viability, Migration, and Invasion of Hepatocellular Carcinoma via Sponging miR-424-5p
Xinying Shen, Yong Li, Fan He & Jian Kong
Pages: 6807-6819
Published online: 04 Aug 2020
AbstractforLncRNA CDKN2B-AS1 Promotes Cell Viability, Migration, and Invasion of Hepatocellular Carcinoma via Sponging miR-424-5p | Full Text | References | PDF (11.2 MB) | EPUB
  • 81 Views
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Article
The Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer
Xiaojing Bai, Yumei Jiang, Xinwei Zhang, Meiyu Wang, Juanhua Tian, Lijun Mu & Yuefeng Du
Pages: 6821-6826
Published online: 04 Aug 2020
AbstractforThe Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer | Full Text | References | PDF (249.7 KB) | EPUB
  • 132 Views
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Article
CircEPSTI1 Promotes the Progression of Non-Small Cell Lung Cancer Through miR-145/HMGB3 Axis
Yuanyuan Xie, Li Wang & Danfen Yang
Pages: 6827-6836
Published online: 04 Aug 2020
AbstractforCircEPSTI1 Promotes the Progression of Non-Small Cell Lung Cancer Through miR-145/HMGB3 Axis | Full Text | References | PDF (26.7 MB) | EPUB
  • 63 Views
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Article
lncRNA TUG1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma via Regulating miR-29c-3p/COL1A1 Axis
Wei Zhao, Xue Jiang & Shuxia Yang
Pages: 6837-6847
Published online: 04 Aug 2020
AbstractforlncRNA TUG1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma via Regulating miR-29c-3p/COL1A1 Axis | Full Text | References | PDF (52.2 MB) | EPUB
  • 67 Views
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Article
Circ_0046599 Promotes the Development of Hepatocellular Carcinoma by Regulating the miR-1258/RPN2 Network
Quangang Fang, Haiyun Liu, Aiqun Zhou, Huaping Zhou & Zhiyong Zhang
Pages: 6849-6860
Published online: 04 Aug 2020
AbstractforCirc_0046599 Promotes the Development of Hepatocellular Carcinoma by Regulating the miR-1258/RPN2 Network | Full Text | References | PDF (8 MB) | EPUB
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Corrigendum

Correction
Glucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma [Corrigendum]
Pages: 6861-6862
Published online: 05 Aug 2020
CitationforGlucosamine-6-Phosphate Isomerase 1 Promotes Tumor Progression and Indicates Poor Prognosis in Hepatocellular Carcinoma [Corrigendum] | Full Text | PDF (14.8 MB) | EPUB
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Correction
Upregulation of hsa_circRNA_102958 Indicates Poor Prognosis and Promotes Ovarian Cancer Progression Through miR-1205/SH2D3A Axis [Corrigendum]
Page: 6863
Published online: 04 Aug 2020
CitationforUpregulation of hsa_circRNA_102958 Indicates Poor Prognosis and Promotes Ovarian Cancer Progression Through miR-1205/SH2D3A Axis [Corrigendum] | Full Text | PDF (161.5 KB) | EPUB
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Original Research

Article
The Down-Regulation of TrkB Alleviates the Malignant Biological Behavior and Cancer Stem-Like Property of Laryngeal Cancer
Xiaoyan Hu, Wujun Zou, Dianzhong Liu, Gang Qin & Liang Jiang
Pages: 6865-6875
Published online: 05 Aug 2020
AbstractforThe Down-Regulation of TrkB Alleviates the Malignant Biological Behavior and Cancer Stem-Like Property of Laryngeal Cancer | Full Text | References | PDF (71 MB) | EPUB
  • 95 Views
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Article
Transcriptome-Wide 5-Methylcytosine Functional Profiling of Long Non-Coding RNA in Hepatocellular Carcinoma
Yuting He, Qingmiao Shi, Yize Zhang, Xin Yuan & Zujiang Yu
Pages: 6877-6885
Published online: 04 Aug 2020
AbstractforTranscriptome-Wide 5-Methylcytosine Functional Profiling of Long Non-Coding RNA in Hepatocellular Carcinoma | Full Text | References | PDF (25.9 MB) | EPUB
  • 90 Views
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Case Series

Case Report
Application of Computer-Aided Design (CAD) and Three-Dimensional (3D) Visualization Technologies in the Diagnosis and Treatment of Refractory Thyroid Tumors
Yi-Bo Chen, Zhao-Hui Wang, Gui-Ming Fu, Quan-Xin Wan, Xiao-Jing Li & Jin Chen
Pages: 6887-6894
Published online: 05 Aug 2020
AbstractforApplication of Computer-Aided Design (CAD) and Three-Dimensional (3D) Visualization Technologies in the Diagnosis and Treatment of Refractory Thyroid Tumors | Full Text | References | PDF (53.1 MB) | EPUB
  • 85 Views
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Original Research

Article
LncRNA MAFG-AS1 Accelerates Cell Migration, Invasion and Aerobic Glycolysis of Esophageal Squamous Cell Carcinoma Cells via miR-765/PDX1 Axis
Cui-juan Qian, Zhu-rong Xu, Lu-yan Chen, Yi-chao Wang & Jun Yao
Pages: 6895-6908
Published online: 05 Aug 2020
AbstractforLncRNA MAFG-AS1 Accelerates Cell Migration, Invasion and Aerobic Glycolysis of Esophageal Squamous Cell Carcinoma Cells via miR-765/PDX1 Axis | Full Text | References | PDF (36.9 MB) | EPUB
  • 78 Views
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Article
RETRACTED ARTICLE: Clinical Significance of Down-Regulated CD70 and CD27 Expression in Poor Prognosis of Esophageal Squamous Cell Carcinoma
Ting-ting Shan, Xuan Zhao, Zhen Zhang, Jing-pu Wang, Yi Zhang, Yang Yang & Song Zhao
Pages: 6909-6920
Published online: 05 Aug 2020
AbstractforRETRACTED ARTICLE: Clinical Significance of Down-Regulated CD70 and CD27 Expression in Poor Prognosis of Esophageal Squamous Cell Carcinoma | PDF (6.6 MB)
  • 14 Views
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Article
Discovery of Ebselen as an Inhibitor of 6PGD for Suppressing Tumor Growth
Qi Feng, Xiuru Li, Wenjing Sun, Yubo Li, Yu Yuan, Baozhang Guan & Shuai Zhang
Pages: 6921-6934
Published online: 05 Aug 2020
AbstractforDiscovery of Ebselen as an Inhibitor of 6PGD for Suppressing Tumor Growth | Full Text | References | PDF (1.3 MB) | EPUB
  • 135 Views
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Article
RETRACTED ARTICLE: Silenced Myeloblastosis Protein Suppresses Oral Tongue Squamous Cell Carcinoma via the microRNA-130a/Cylindromatosis Axis
Ran Yang, Yusen Shui, Shoushan Hu, Kun Zhang, Yuru Wang & Yiran Peng
Pages: 6935-6946
Published online: 05 Aug 2020
AbstractforRETRACTED ARTICLE: Silenced Myeloblastosis Protein Suppresses Oral Tongue Squamous Cell Carcinoma via the microRNA-130a/Cylindromatosis Axis | PDF (7.4 MB)
  • 14 Views
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Article
AURKB Promotes the Metastasis of Gastric Cancer, Possibly by Inducing EMT
Zhen Wang, Zhu Yu, Gong-he Wang, Yi-ming Zhou, Jian-ping Deng, Yue Feng, Jun-qiang Chen & Lei Tian
Pages: 6947-6958
Published online: 05 Aug 2020
AbstractforAURKB Promotes the Metastasis of Gastric Cancer, Possibly by Inducing EMT | Full Text | References | PDF (50.5 MB) | EPUB
  • 102 Views
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Article
MiR-218-5p Suppresses the Progression of Retinoblastoma Through Targeting NACC1 and Inhibiting the AKT/mTOR Signaling Pathway
Li Li, Hua Yu & Qian Ren
Pages: 6959-6967
Published online: 06 Aug 2020
AbstractforMiR-218-5p Suppresses the Progression of Retinoblastoma Through Targeting NACC1 and Inhibiting the AKT/mTOR Signaling Pathway | Full Text | References | PDF (7 MB) | EPUB
  • 83 Views
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Article
Inhibition of Multiple Myeloma Using 5-Aza-2ʹ-Deoxycytidine and Bortezomib-Loaded Self-Assembling Nanoparticles
Feifei Che, Jiao Chen, Jingying Dai & Xingchao Liu
Pages: 6969-6976
Published online: 06 Aug 2020
AbstractforInhibition of Multiple Myeloma Using 5-Aza-2ʹ-Deoxycytidine and Bortezomib-Loaded Self-Assembling Nanoparticles | Full Text | References | PDF (27.4 MB) | EPUB
  • 98 Views
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Article
Large Scale, Multicenter, Prospective Study of Apatinib in Advanced Gastric Cancer: A Real-World Study from China
Wanren Peng, Fenglin Zhang, Zishu Wang, Dongliang Li, Yifu He, Zhongliang Ning, Lili Sheng, Jidong Wang, Xiaoyang Xia, Changjun Yu, Zian Wang, Yong Zhao, Hui Liang, Bing Hu, Cuiling Sun, Daoqin Wang, Yunsheng Cheng, Ming Pan, Liming Xia, Xinglai Guo, Yanshun Zhang, Zhiqiang Hu, Xinzhong Li, Lin Lu, Jun Zhang, Hong Qian, Hua Xie & Guoping Sun
Pages: 6977-6985
Published online: 06 Aug 2020
AbstractforLarge Scale, Multicenter, Prospective Study of Apatinib in Advanced Gastric Cancer: A Real-World Study from China | Full Text | References | PDF (1.2 MB) | EPUB
  • 133 Views
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Review

Review Article
New Advances in Canonical Wnt/β-Catenin Signaling in Cancer
Xiaolan Wen, Yanling Wu, Annoor Awadasseid, Yoshimasa Tanaka & Wen Zhang
Pages: 6987-6998
Published online: 06 Aug 2020
AbstractforNew Advances in Canonical Wnt/β-Catenin Signaling in Cancer | Full Text | References | PDF (10.6 MB) | EPUB
  • 263 Views
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Original Research

Article
Surgical Treatment Outcomes of Spinal Metastases of Nasopharyngeal Carcinoma: The First Report of 30 Patients from a Single Center
Jian Yang, Jinbo Hu, Da Wang, Qi Jia, Jian Jiao & Jianru Xiao
Pages: 6999-7008
Published online: 06 Aug 2020
AbstractforSurgical Treatment Outcomes of Spinal Metastases of Nasopharyngeal Carcinoma: The First Report of 30 Patients from a Single Center | Full Text | References | PDF (2.8 MB) | EPUB
  • 74 Views
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Article
Correlation Between Hemoglobin Levels and the Prognosis of First-Line Chemotherapy in Patients with Advanced Gastric Cancer
Qing Wei, Xing Yuan, Qi Xu, Jingjing Li, Lei Chen & Jieer Ying
Pages: 7009-7019
Published online: 07 Aug 2020
AbstractforCorrelation Between Hemoglobin Levels and the Prognosis of First-Line Chemotherapy in Patients with Advanced Gastric Cancer | Full Text | References | PDF (5.4 MB) | EPUB
  • 98 Views
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Article
NRP1 is a Prognostic Factor and Promotes the Growth and Migration of Cells in Intrahepatic Cholangiocarcinoma
Yong-Na Wu, Li-Hong He, Zhong-Tian Bai & Xun Li
Pages: 7021-7032
Published online: 07 Aug 2020
AbstractforNRP1 is a Prognostic Factor and Promotes the Growth and Migration of Cells in Intrahepatic Cholangiocarcinoma | Full Text | References | PDF (30.1 MB) | EPUB
  • 70 Views
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Article
Altered Functional Connectivity Density in Young Survivors of Acute Lymphoblastic Leukemia Using Resting-State fMRI
Linglong Chen, Yaru Zhan, Fei He, Shouhua Zhang, Lin Wu, Honghan Gong, Fuqing Zhou, Xianjun Zeng & Haibo Xu
Pages: 7033-7041
Published online: 07 Aug 2020
AbstractforAltered Functional Connectivity Density in Young Survivors of Acute Lymphoblastic Leukemia Using Resting-State fMRI | Full Text | References | PDF (33.9 MB) | EPUB
  • 71 Views
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Article
Hypermethylation of the IRAK3-Activated MAPK Signaling Pathway to Promote the Development of Glioma
Xinghai Wu, Yian Ouyang, Bin Wang, Jian Lin & Yun Bai
Pages: 7043-7059
Published online: 07 Aug 2020
AbstractforHypermethylation of the IRAK3-Activated MAPK Signaling Pathway to Promote the Development of Glioma | Full Text | References | PDF (17 MB) | EPUB
  • 72 Views
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Article
Construction and Comprehensive Analysis of a ceRNA Network to Reveal Potential Novel Biomarkers for Triple-Negative Breast Cancer
Lifei Ma, Guiqin Song, Meiyu Li, Xiuqing Hao, Yong Huang, Jinping Lan, Siqian Yang, Zetian Zhang, Guohui Zhang & Jiao Mu
Pages: 7061-7075
Published online: 07 Aug 2020
AbstractforConstruction and Comprehensive Analysis of a ceRNA Network to Reveal Potential Novel Biomarkers for Triple-Negative Breast Cancer | Full Text | References | PDF (14.6 MB) | EPUB
  • 96 Views
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Article
Performance of a Nomogram Based on the Integration of Inflammation Markers with Tumor Staging in Prognosis Prediction of Stage III Colorectal Cancer
Lin Wang, Jun Xiao, Min-Zhe Li, Wen-Hao Teng, Jing Jia, Lu Lin, Sheng Liu, Xing-ming Ye, Wei-Dong Zang & Ying Chen
Pages: 7077-7085
Published online: 07 Aug 2020
AbstractforPerformance of a Nomogram Based on the Integration of Inflammation Markers with Tumor Staging in Prognosis Prediction of Stage III Colorectal Cancer | Full Text | References | PDF (11.4 MB) | EPUB
  • 61 Views
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Article
RETRACTED ARTICLE: microRNA-26a Directly Targeting MMP14 and MMP16 Inhibits the Cancer Cell Proliferation, Migration and Invasion in Cutaneous Squamous Cell Carcinoma
Wang Zheng, Zong-Yu Li, De-Lai Zhao, Xing-Long Li & Rui Liu
Pages: 7087-7095
Published online: 10 Aug 2020
AbstractforRETRACTED ARTICLE: microRNA-26a Directly Targeting MMP14 and MMP16 Inhibits the Cancer Cell Proliferation, Migration and Invasion in Cutaneous Squamous Cell Carcinoma | PDF (28.5 MB)
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Article
Normal Absolute Monocyte Count at the Time of Relapse is Associated with Improved Survival After First Salvage Therapy in Adult Patients with Early Relapsed B-Lineage Acute Lymphoblastic Leukemia
Yi-fen Shi, Na Wang, Zi-yang Huang, Rong-rong Chen, Yi-sha Huang, Yi-yi Zhu, Chong-yun Xing, Bin Liang, Kang Yu & Jian-hua Feng
Pages: 7097-7105
Published online: 10 Aug 2020
AbstractforNormal Absolute Monocyte Count at the Time of Relapse is Associated with Improved Survival After First Salvage Therapy in Adult Patients with Early Relapsed B-Lineage Acute Lymphoblastic Leukemia | Full Text | References | PDF (2.1 MB) | EPUB
  • 91 Views
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Article
Circular RNA MAT2B Induces Colorectal Cancer Proliferation via Sponging miR-610, Resulting in an Increased E2F1 Expression
Jian Pei Zhao & Li Li Chen
Pages: 7107-7116
Published online: 10 Aug 2020
AbstractforCircular RNA MAT2B Induces Colorectal Cancer Proliferation via Sponging miR-610, Resulting in an Increased E2F1 Expression | Full Text | References | PDF (1.3 MB) | EPUB
  • 75 Views
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Article
Circular RNA circNHSL1 Contributes to Gastric Cancer Progression Through the miR-149-5p/YWHAZ Axis
Chunying Hui, Lei Tian & Xinling He
Pages: 7117-7130
Published online: 12 Aug 2020
AbstractforCircular RNA circNHSL1 Contributes to Gastric Cancer Progression Through the miR-149-5p/YWHAZ Axis | Full Text | References | PDF (31.4 MB) | EPUB
  • 86 Views
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Article
MiR-26a-5p Serves as an Oncogenic MicroRNA in Non-Small Cell Lung Cancer by Targeting FAF1
Ming-fan Ye, Dong Lin, Wu-jin Li, Hai-peng Xu & Jing Zhang
Pages: 7131-7142
Published online: 11 Aug 2020
AbstractforMiR-26a-5p Serves as an Oncogenic MicroRNA in Non-Small Cell Lung Cancer by Targeting FAF1 | Full Text | References | PDF (45.8 MB) | EPUB
  • 100 Views
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Article
Analysis of Risk Factors for Lymph Node Metastases in Elderly Patients with Papillary Thyroid Micro-Carcinoma
Gui-Ming Fu, Zhao-Hui Wang, Yi-Bo Chen, Chun-Hua Li, Yue-Jia Zhang, Xiao-Jing Li & Quan-Xin Wan
Pages: 7143-7149
Published online: 11 Aug 2020
AbstractforAnalysis of Risk Factors for Lymph Node Metastases in Elderly Patients with Papillary Thyroid Micro-Carcinoma | Full Text | References | PDF (2 MB) | EPUB
  • 67 Views
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Article
Risk Factors for Lymph Node Metastasis and Survival Outcomes in Colorectal Neuroendocrine Tumors
Zijian Wu, Zhijie Wang, Zhaoxu Zheng, Jianjun Bi, Xishan Wang & Qiang Feng
Pages: 7151-7164
Published online: 11 Aug 2020
AbstractforRisk Factors for Lymph Node Metastasis and Survival Outcomes in Colorectal Neuroendocrine Tumors | Full Text | References | PDF (3.6 MB) | EPUB
  • 96 Views
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Article
Risk Stratification of Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Treated with Chemo-Radiotherapy: An Institutional Analysis
Amna Sher, Sowmini Medavaram, Barbara Nemesure, Sean Clouston & Roger Keresztes
Pages: 7165-7171
Published online: 11 Aug 2020
AbstractforRisk Stratification of Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Treated with Chemo-Radiotherapy: An Institutional Analysis | Full Text | References | PDF (308.6 KB) | EPUB
  • 63 Views
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Article
The Prognostic Value of Inflammation Factors in Hepatocellular Carcinoma Patients with Hepatic Artery Interventional Treatments: A Retrospective Study
Linghong Guo, Honghong Ren, Lutong Pu, Xingyu Zhu, Yin Liu & Xuelei Ma
Pages: 7173-7188
Published online: 13 Aug 2020
AbstractforThe Prognostic Value of Inflammation Factors in Hepatocellular Carcinoma Patients with Hepatic Artery Interventional Treatments: A Retrospective Study | Full Text | References | PDF (1.3 MB) | EPUB
  • 90 Views
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Article
ENST00000430471 Promotes Development and Metastasis of Colorectal Cancer by Regulating the Expression of YBX-1
Zhenghai Zhu, Xiaoxin Zhang, Ying Zhou, Jie Cheng & Zipeng Xu
Pages: 7189-7197
Published online: 11 Aug 2020
AbstractforENST00000430471 Promotes Development and Metastasis of Colorectal Cancer by Regulating the Expression of YBX-1 | Full Text | References | PDF (41.4 MB) | EPUB
  • 62 Views
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Article
The Effect of Admission Serum Magnesium on the Acute Kidney Injury Among Patients with Malignancy
Daoqi Shen, Yimei Wang, Jiarui Xu, Yang Li, Xiaohong Chen, Man Guo, Xuemei Geng, Xiaoqiang Ding & Xialian Xu
Pages: 7199-7207
Published online: 11 Aug 2020
AbstractforThe Effect of Admission Serum Magnesium on the Acute Kidney Injury Among Patients with Malignancy | Full Text | References | PDF (13.5 MB) | EPUB
  • 79 Views
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Retraction

Retraction
Silencing of lncRNA LINC00346 Inhibits the Proliferation and Promotes the Apoptosis of Colorectal Cancer Cells Through Inhibiting JAK1/STAT3 Signaling [Retraction]
Page: 7209
Published online: 12 Aug 2020
CitationforSilencing of lncRNA LINC00346 Inhibits the Proliferation and Promotes the Apoptosis of Colorectal Cancer Cells Through Inhibiting JAK1/STAT3 Signaling [Retraction] | Full Text | PDF (167.2 KB) | EPUB
  • 42 Views
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Original Research

Article
Long Noncoding RNA LINC00173 Promotes NUTF2 Expression Through Sponging miR-765 and Facilitates Tumorigenesis in Glioma
Qinghua Du, Jin Liu, Da Tian, Xuelei Zhang, Jinwei Zhu, Weiwen Qiu & Jun Wu
Pages: 7211-7217
Published online: 12 Aug 2020
AbstractforLong Noncoding RNA LINC00173 Promotes NUTF2 Expression Through Sponging miR-765 and Facilitates Tumorigenesis in Glioma | Full Text | References | PDF (4.3 MB) | EPUB
  • 93 Views
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Article
The circ-AMOTL1/ENO1 Axis Implicated in the Tumorigenesis of OLP-Associated Oral Squamous Cell Carcinoma
Jin Liu, Qiaozhen Yang, Hongying Sun, Xiaxia Wang, Hexige Saiyin & Hui Zhang
Pages: 7219-7230
Published online: 12 Aug 2020
AbstractforThe circ-AMOTL1/ENO1 Axis Implicated in the Tumorigenesis of OLP-Associated Oral Squamous Cell Carcinoma | Full Text | References | PDF (11.9 MB) | EPUB
  • 74 Views
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Article
Insulin Reduces the Efficacy of Vemurafenib and Trametinib in Melanoma Cells
Marta Osrodek, Michal Rozanski & Malgorzata Czyz
Pages: 7231-7250
Published online: 13 Aug 2020
AbstractforInsulin Reduces the Efficacy of Vemurafenib and Trametinib in Melanoma Cells | Full Text | References | PDF (11.3 MB) | EPUB
  • 66 Views
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Article
RETRACTED ARTICLE: ZFAS1 Promotes Cisplatin Resistance via Suppressing miR-421 Expression in Oral Squamous Cell Carcinoma
Xiaolong Wang, Rui Hao, Fengjuan Wang & Fan Wang
Pages: 7251-7262
Published online: 13 Aug 2020
AbstractforRETRACTED ARTICLE: ZFAS1 Promotes Cisplatin Resistance via Suppressing miR-421 Expression in Oral Squamous Cell Carcinoma | PDF (7.4 MB)
  • 41 Views
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Review

Review Article
Development and Clinical Prospects of Techniques to Separate Circulating Tumor Cells from Peripheral Blood
Cheng Tian, Xinhua Xu, Yuke Wang, Dailong Li, Haiyan Lu & Ziwei Yang
Pages: 7263-7275
Published online: 14 Aug 2020
AbstractforDevelopment and Clinical Prospects of Techniques to Separate Circulating Tumor Cells from Peripheral Blood | Full Text | References | PDF (968.2 KB) | EPUB
  • 130 Views
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Original Research

Article
NEAT1 Knockdown Suppresses the Cisplatin Resistance in Ovarian Cancer by Regulating miR-770-5p/PARP1 Axis
Mingzhe Zhu, Lei Yang & Xin Wang
Pages: 7277-7289
Published online: 14 Aug 2020
AbstractforNEAT1 Knockdown Suppresses the Cisplatin Resistance in Ovarian Cancer by Regulating miR-770-5p/PARP1 Axis | Full Text | References | PDF (7.7 MB) | EPUB
  • 111 Views
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Article
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p
Weisheng Guo, Lin Zhao, Guangya Wei, Peng Liu, Yu Zhang & Liran Fu
Pages: 7291-7303
Published online: 14 Aug 2020
AbstractforBlocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p | Full Text | References | PDF (8.4 MB) | EPUB
  • 70 Views
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Article
Allicin Inhibits Proliferation by Decreasing IL-6 and IFN-β in HCMV-Infected Glioma Cells
Zelin Yang, Jizao Du, Jinjin Zhu, Yuxi Rong, Shaohuai Chen, Lisheng Yu, Xiangyang Deng, Xiaojia Zhang, Hansong Sheng, Liang Yang, Xiangqi Lu, Dandong Li, Bo Yin & Jian Lin
Pages: 7305-7317
Published online: 17 Aug 2020
AbstractforAllicin Inhibits Proliferation by Decreasing IL-6 and IFN-β in HCMV-Infected Glioma Cells | Full Text | References | PDF (4.8 MB) | EPUB
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Retraction

Retraction
MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2 [Retraction]
Page: 7319
Published online: 17 Aug 2020
CitationforMiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2 [Retraction] | Full Text | PDF (163.3 KB) | EPUB
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Review

Review Article
Pembrolizumab in Combination with Axitinib as First-Line Treatment for Patients with Renal Cell Carcinoma (RCC): Evidence to Date
Vincent Chau & Marijo Bilusic
Pages: 7321-7330
Published online: 17 Aug 2020
AbstractforPembrolizumab in Combination with Axitinib as First-Line Treatment for Patients with Renal Cell Carcinoma (RCC): Evidence to Date | Full Text | References | PDF (1.6 MB) | EPUB
  • 177 Views
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Original Research

Article
Intratreatment Tumor Volume Change During Definitive Chemoradiotherapy is Predictive for Treatment Outcome of Patients with Esophageal Carcinoma
Ruihong Huang, Hong Guo, Jianzhou Chen, Tiantian Zhai, Junwei Chen, Kun Lin, Zhijian Chen, Derui Li & Chuangzhen Chen
Pages: 7331-7339
Published online: 18 Aug 2020
AbstractforIntratreatment Tumor Volume Change During Definitive Chemoradiotherapy is Predictive for Treatment Outcome of Patients with Esophageal Carcinoma | Full Text | References | PDF (1.5 MB) | EPUB
  • 63 Views
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Retraction

Retraction
Lidocaine Suppresses Cell Proliferation and Aerobic Glycolysis by Regulating circHOMER1/miR-138-5p/HEY1 Axis in Colorectal Cancer [Retraction]
Page: 7341
Published online: 18 Aug 2020
CitationforLidocaine Suppresses Cell Proliferation and Aerobic Glycolysis by Regulating circHOMER1/miR-138-5p/HEY1 Axis in Colorectal Cancer [Retraction] | Full Text | PDF (163.8 KB) | EPUB
  • 50 Views
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Original Research

Article
Adverse Factors of Treatment Response and Overall Survival in Pediatric and Adult Patients with Pineoblastoma
Xu-Lei Huo, Bo Wang, Gui-Jun Zhang, Jun-Peng Ma, Liang Wang, Li-Wei Zhang, Xiao-Ying Xu, Xiao-Jie Li, Huan Li, Da Li, Jun-Ting Zhang & Zhen Wu
Pages: 7343-7351
Published online: 18 Aug 2020
AbstractforAdverse Factors of Treatment Response and Overall Survival in Pediatric and Adult Patients with Pineoblastoma | Full Text | References | PDF (2.2 MB) | EPUB
  • 117 Views
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Article
Circ-SAR1A Promotes Renal Cell Carcinoma Progression Through miR-382/YBX1 Axis
Xiaolei Zhao, Zhenhua Zhao, Wenchao Xu, Hui Liu, Junkai Chang, Weibo Xu, Song Li, Songqiang Cao & Junqing Hou
Pages: 7353-7361
Published online: 18 Aug 2020
AbstractforCirc-SAR1A Promotes Renal Cell Carcinoma Progression Through miR-382/YBX1 Axis | Full Text | References | PDF (7.4 MB) | EPUB
  • 71 Views
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Article
Anti-Proliferative and Apoptosis-Promoting Effect of microRNA-125b on Pancreatic Cancer by Targeting NEDD9 via PI3K/AKT Signaling
Yuzheng Xue, Yao Zhong, Tielong Wu, Yingyue Sheng, Yuanyuan Dai, Lingling Xu & Chuanqing Bao
Pages: 7363-7373
Published online: 18 Aug 2020
AbstractforAnti-Proliferative and Apoptosis-Promoting Effect of microRNA-125b on Pancreatic Cancer by Targeting NEDD9 via PI3K/AKT Signaling | Full Text | References | PDF (7.1 MB) | EPUB
  • 69 Views
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Article
Nomogram Predicting Overall Survival of Resected Locally Advanced Rectal Cancer Patients with Neoadjuvant Chemoradiotherapy
Jianyuan Song, Zhuhong Chen, Daxin Huang, Yimin Wu, Zhuangbin Lin, Pan Chi & Benhua Xu
Pages: 7375-7382
Published online: 18 Aug 2020
AbstractforNomogram Predicting Overall Survival of Resected Locally Advanced Rectal Cancer Patients with Neoadjuvant Chemoradiotherapy | Full Text | References | PDF (2.5 MB) | EPUB
  • 92 Views
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Article
Circ_0015756 Aggravates Hepatocellular Carcinoma Development by Regulating FGFR1 via Sponging miR-610
Weisheng Guo, Lin Zhao, Guangya Wei, Peng Liu, Yu Zhang & Liran Fu
Pages: 7383-7394
Published online: 18 Aug 2020
AbstractforCirc_0015756 Aggravates Hepatocellular Carcinoma Development by Regulating FGFR1 via Sponging miR-610 | Full Text | References | PDF (6.3 MB) | EPUB
  • 67 Views
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Article
Predicting Recurrence in Endometrial Cancer Based on a Combination of Classical Parameters and Immunohistochemical Markers
Peng Jiang, Jin Huang, Ying Deng, Jing Hu, Zhen Huang, Mingzhu Jia, Jiaojiao Long & Zhuoying Hu
Pages: 7395-7403
Published online: 18 Aug 2020
AbstractforPredicting Recurrence in Endometrial Cancer Based on a Combination of Classical Parameters and Immunohistochemical Markers | Full Text | References | PDF (2.1 MB) | EPUB
  • 81 Views
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Article
Δ133p53/FLp53 Predicts Poor Clinical Outcome in Esophageal Squamous Cell Carcinoma
Qimin Tu, Hongjian Gong, Chunhui Yuan, Gao Liu, Jinqi Huang, Zhichao Li & Jianfei Luo
Pages: 7405-7417
Published online: 18 Aug 2020
AbstractforΔ133p53/FLp53 Predicts Poor Clinical Outcome in Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (3.9 MB) | EPUB
  • 76 Views
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Article
15-PGDH Expression in Gastric Cancer: A Potential Role in Anti-Tumor Immunity
Yaling Li, Junjie Li, Juanjuan Dong, Lei Zhang, Dongling Liu, Jianzheng He, Yali She, Chengxu Ma & Yongqi Liu
Pages: 7419-7426
Published online: 19 Aug 2020
Abstractfor15-PGDH Expression in Gastric Cancer: A Potential Role in Anti-Tumor Immunity | Full Text | References | PDF (1.5 MB) | EPUB
  • 80 Views
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Article
Impact of Somatic Mutations in Non-Small-Cell Lung Cancer: A Retrospective Study of a Chinese Cohort
Hai-bo Shen, Jie Li, Yuan-shan Yao, Zhen-hua Yang, Yin-jie Zhou, Wei Chen & Tian-jun Hu
Pages: 7427-7437
Published online: 19 Aug 2020
AbstractforImpact of Somatic Mutations in Non-Small-Cell Lung Cancer: A Retrospective Study of a Chinese Cohort | Full Text | References | PDF (5.3 MB) | EPUB
  • 78 Views
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Article
Predictors of Intravesical Recurrence After Radical Nephroureterectomy and Prognosis in Patients with Upper Tract Urothelial Carcinoma
Yun-Ren Li, Kai-Jie Yu, Ying-Hsu Chang, Po-Hung Lin, I-Hung Shao, Hung-Cheng Kan, Yuan-Cheng Chu, Cheng-Keng Chuang, See-Tong Pang & Chung-Yi Liu
Pages: 7439-7450
Published online: 19 Aug 2020
AbstractforPredictors of Intravesical Recurrence After Radical Nephroureterectomy and Prognosis in Patients with Upper Tract Urothelial Carcinoma | Full Text | References | PDF (781.2 KB) | EPUB
  • 78 Views
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Article
LncRNA DLX6-AS1 Promotes the Progression of Neuroblastoma by Activating STAT2 via Targeting miR-506-3p
Yanping Hu, Huifang Sun, Jiting Hu & Xiaomin Zhang
Pages: 7451-7463
Published online: 19 Aug 2020
AbstractforLncRNA DLX6-AS1 Promotes the Progression of Neuroblastoma by Activating STAT2 via Targeting miR-506-3p | Full Text | References | PDF (9.1 MB) | EPUB
  • 79 Views
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Retraction

Retraction
Castleman’s Disease in the HIV-Endemic Setting [Retraction]
Page: 7465
Published online: 20 Aug 2020
CitationforCastleman’s Disease in the HIV-Endemic Setting [Retraction] | Full Text | PDF (167 KB) | EPUB
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Original Research

Article
High Mean Corpuscular Volume as a Predictor of Poor Overall Survival in Patients with Esophageal Cancer Receiving Concurrent Chemoradiotherapy
Ke-jie Li, Wen-yue Gu, Xiao-fang Xia, Ping Zhang, Chang-lin Zou & Zheng-hua Fei
Pages: 7467-7474
Published online: 20 Aug 2020
AbstractforHigh Mean Corpuscular Volume as a Predictor of Poor Overall Survival in Patients with Esophageal Cancer Receiving Concurrent Chemoradiotherapy | Full Text | References | PDF (943.4 KB) | EPUB
  • 102 Views
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Article
Effect of Chitosan Magnetic Nanoparticles Loaded with Ang2-siRNA Plasmids on the Growth of Melanoma Xenografts in Nude Mice
Xiuying Shan, Wenjun Yu, Xuejun Ni, Tingting Xu, Chen Lei, Zhaoliang Liu, Xuefeng Hu, Yanding Zhang, Beichen Cai & Biao Wang
Pages: 7475-7485
Published online: 20 Aug 2020
AbstractforEffect of Chitosan Magnetic Nanoparticles Loaded with Ang2-siRNA Plasmids on the Growth of Melanoma Xenografts in Nude Mice | Full Text | References | PDF (6.4 MB) | EPUB
  • 102 Views
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Article
Circ-ZNF609 Accelerates the Radioresistance of Prostate Cancer Cells by Promoting the Glycolytic Metabolism Through miR-501-3p/HK2 Axis
Shuangkuan Du, Pengjie Zhang, Wei Ren, Fan Yang & Chun Du
Pages: 7487-7499
Published online: 20 Aug 2020
AbstractforCirc-ZNF609 Accelerates the Radioresistance of Prostate Cancer Cells by Promoting the Glycolytic Metabolism Through miR-501-3p/HK2 Axis | Full Text | References | PDF (8.1 MB) | EPUB
  • 98 Views
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Article
Exosomal CircGDI2 Suppresses Oral Squamous Cell Carcinoma Progression Through the Regulation of MiR-424-5p/SCAI Axis
Yu Zhang, Kaiqi Tang, Lizhu Chen, Meng Du & Zhi Qu
Pages: 7501-7514
Published online: 20 Aug 2020
AbstractforExosomal CircGDI2 Suppresses Oral Squamous Cell Carcinoma Progression Through the Regulation of MiR-424-5p/SCAI Axis | Full Text | References | PDF (10.9 MB) | EPUB
  • 75 Views
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Article
Clinical Characteristics and Prognostic Analysis of Gynecologic Cancer with Spinal Metastases: A Single-Center Retrospective Study
Shuzhong Liu, Xi Zhou, An Song, Zhen Huo, Siyuan Yao, Yipeng Wang, Yong Liu & Ling-Ya Pan
Pages: 7515-7525
Published online: 20 Aug 2020
AbstractforClinical Characteristics and Prognostic Analysis of Gynecologic Cancer with Spinal Metastases: A Single-Center Retrospective Study | Full Text | References | PDF (3.4 MB) | EPUB
  • 106 Views
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Review

Review Article
The Contradictory Role of Interleukin-33 in Immune Cells and Tumor Immunity
Xujun Zhang, Wenbiao Chen, Ping Zeng, Jia Xu & Hongyan Diao
Pages: 7527-7537
Published online: 21 Aug 2020
AbstractforThe Contradictory Role of Interleukin-33 in Immune Cells and Tumor Immunity | Full Text | References | PDF (1.8 MB) | EPUB
  • 95 Views
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Original Research

Article
RETRACTED ARTICLE: Long Intergenic Non-Coding RNA LINC00922 Aggravates the Malignant Phenotype of Breast Cancer by Regulating the microRNA-424-5p/BDNF Axis
Xin Yue & Zhuo Wang
Pages: 7539-7552
Published online: 21 Aug 2020
AbstractforRETRACTED ARTICLE: Long Intergenic Non-Coding RNA LINC00922 Aggravates the Malignant Phenotype of Breast Cancer by Regulating the microRNA-424-5p/BDNF Axis | PDF (9.5 MB)
  • 19 Views
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Article
The Efficacy of Low Postoperative Radiation Dose in Patients with Advanced Hypopharyngeal Cancer without High-Risk Factors
Hengmin Tao, Zhong Shen, Zhichao Liu & Yumei Wei
Pages: 7553-7560
Published online: 21 Aug 2020
AbstractforThe Efficacy of Low Postoperative Radiation Dose in Patients with Advanced Hypopharyngeal Cancer without High-Risk Factors | Full Text | References | PDF (1.4 MB) | EPUB
  • 53 Views
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Article
Circular RNA circRNA_103809 Accelerates Bladder Cancer Progression and Enhances Chemo-Resistance by Activation of miR-516a-5p/FBXL18 Axis
Weiping Huang, Yongyong Lu, Feng Wang, Xixi Huang & Zhixian Yu
Pages: 7561-7568
Published online: 21 Aug 2020
AbstractforCircular RNA circRNA_103809 Accelerates Bladder Cancer Progression and Enhances Chemo-Resistance by Activation of miR-516a-5p/FBXL18 Axis | Full Text | References | PDF (4.9 MB) | EPUB
  • 80 Views
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Article
Clinicopathological Characteristics of Pseudomyxoma Peritonei Originated from Ovaries
Fengcai Yan, Feng Shi, Xinbao Li, Chunkai Yu, Yulin Lin, Yan Li & Mulan Jin
Pages: 7569-7578
Published online: 21 Aug 2020
AbstractforClinicopathological Characteristics of Pseudomyxoma Peritonei Originated from Ovaries | Full Text | References | PDF (2.3 MB) | EPUB
  • 123 Views
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Article
MicroRNA-421 Inhibits Apoptosis by Downregulating Caspase-3 in Human Colorectal Cancer
Yifan Zhou, Xiaowen Cheng, Yufeng Wan, Tingting Chen, Qing Zhou, Zhengguang Wang & Huaqing Zhu
Pages: 7579-7587
Published online: 21 Aug 2020
AbstractforMicroRNA-421 Inhibits Apoptosis by Downregulating Caspase-3 in Human Colorectal Cancer | Full Text | References | PDF (3.8 MB) | EPUB
  • 87 Views
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Article
Development and Validation of a Clinicopathological-Based Nomogram to Predict the Survival Outcome of Patients with Recurrent Hepatocellular Carcinoma After Hepatectomy Who Underwent Microwave Ablation
Chunhou Qi, Shankai Li & Lei Zhang
Pages: 7589-7600
Published online: 21 Aug 2020
AbstractforDevelopment and Validation of a Clinicopathological-Based Nomogram to Predict the Survival Outcome of Patients with Recurrent Hepatocellular Carcinoma After Hepatectomy Who Underwent Microwave Ablation | Full Text | References | PDF (2.9 MB) | EPUB
  • 62 Views
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Article
Perineural Invasion and Postoperative Complications are Independent Predictors of Early Recurrence and Survival Following Curative Resection of Gastric Cancer
Ling Chen, Jing Lin, Li-Zhu Chen, Yu Chen, Xiao-Jie Wang, Zeng-Qing Guo & Jia-Mi Yu
Pages: 7601-7610
Published online: 21 Aug 2020
AbstractforPerineural Invasion and Postoperative Complications are Independent Predictors of Early Recurrence and Survival Following Curative Resection of Gastric Cancer | Full Text | References | PDF (838.3 KB) | EPUB
  • 86 Views
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Article
Fine-Needle Aspiration of Subcentimeter Thyroid Nodules in the Real-World Management
Chaiho Jeong, Hyunsam Kim, Jeongmin Lee, Jeonghoon Ha, Min-Hee Kim, Moo Il Kang & Dong-Jun Lim
Pages: 7611-7618
Published online: 21 Aug 2020
AbstractforFine-Needle Aspiration of Subcentimeter Thyroid Nodules in the Real-World Management | Full Text | References | PDF (883.7 KB) | EPUB
  • 89 Views
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Review

Review Article
Effects of Anesthesia on Postoperative Recurrence and Metastasis of Malignant Tumors
Xiaoqing Fan, Delong Wang, Xueran Chen & Ruiting Wang
Pages: 7619-7633
Published online: 24 Aug 2020
AbstractforEffects of Anesthesia on Postoperative Recurrence and Metastasis of Malignant Tumors | Full Text | References | PDF (412.5 KB) | EPUB
  • 116 Views
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Original Research

Article
Circ_0000376, a Novel circRNA, Promotes the Progression of Non-Small Cell Lung Cancer Through Regulating the miR-1182/NOVA2 Network
Cui Li, Hai Liu, Qin Niu & Jia Gao
Pages: 7635-7647
Published online: 24 Aug 2020
AbstractforCirc_0000376, a Novel circRNA, Promotes the Progression of Non-Small Cell Lung Cancer Through Regulating the miR-1182/NOVA2 Network | Full Text | References | PDF (11.5 MB) | EPUB
  • 69 Views
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Open Access
Article
Development and Validation of a Model for Predicting Urethral Recurrence in Male Patients with Muscular Invasive Bladder Cancer After Radical Cystectomy Combined with Urinary Diversion
Zeqi Liu, Xuanyu Zhang, Bin Wu, Yueyang Zhao & Song Bai
Pages: 7649-7657
Published online: 24 Aug 2020
AbstractforDevelopment and Validation of a Model for Predicting Urethral Recurrence in Male Patients with Muscular Invasive Bladder Cancer After Radical Cystectomy Combined with Urinary Diversion | Full Text | References | PDF (3.4 MB) | EPUB
  • 68 Views
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Article
Endoscopic or Surgical Resection for Patients with 2–5cm Gastric Gastrointestinal Stromal Tumors: A Single-Center 12-Year Experience from China
Tianxiang Lei, Fengbo Tan, Heli Liu, Miao Ouyang, Haiyan Zhou, Peng Liu, Xianhui Zhao & Bin Li
Pages: 7659-7670
Published online: 24 Aug 2020
AbstractforEndoscopic or Surgical Resection for Patients with 2–5cm Gastric Gastrointestinal Stromal Tumors: A Single-Center 12-Year Experience from China | Full Text | References | PDF (4.4 MB) | EPUB
  • 93 Views
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Article
WAVE2 Enhanced Hepatic Stellate Cells Activity in Colorectal Liver Metastases
Fengbo Tan, Dongren He, Kuan Hu, Dong Wang, Sai Zhang, Juanni Li, Zhiming Wang & Yiming Tao
Pages: 7671-7680
Published online: 24 Aug 2020
AbstractforWAVE2 Enhanced Hepatic Stellate Cells Activity in Colorectal Liver Metastases | Full Text | References | PDF (6.2 MB) | EPUB
  • 56 Views
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Article
Skin Metastasis of Gastrointestinal Stromal Tumors: A Case Series and Literature Review
Peng Liu, Fengbo Tan, Heli Liu, Jie Ge, Sheng Liu, Tianxiang Lei & Xianhui Zhao
Pages: 7681-7690
Published online: 24 Aug 2020
AbstractforSkin Metastasis of Gastrointestinal Stromal Tumors: A Case Series and Literature Review | Full Text | References | PDF (2.1 MB) | EPUB
  • 84 Views
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Article
MALAT1 Promotes Cell Tumorigenicity Through Regulating miR-515-5p/EEF2 Axis in Non-Small Cell Lung Cancer
Feng Rong, Liang Liu, Can Zou, Jing Zeng & Yasheng Xu
Pages: 7691-7701
Published online: 24 Aug 2020
AbstractforMALAT1 Promotes Cell Tumorigenicity Through Regulating miR-515-5p/EEF2 Axis in Non-Small Cell Lung Cancer | Full Text | References | PDF (6.8 MB) | EPUB
  • 69 Views
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Article
PINK1 Overexpression Promotes Cell Migration and Proliferation via Regulation of Autophagy and Predicts a Poor Prognosis in Lung Cancer Cases
Xiao Lu, Quan-Xing Liu, Jiao Zhang, Dong Zhou, Gui-Xue Yang, Man-Yuan Li, Yuan Qiu, Qian Chen, Hong Zheng & Ji-Gang Dai
Pages: 7703-7714
Published online: 24 Aug 2020
AbstractforPINK1 Overexpression Promotes Cell Migration and Proliferation via Regulation of Autophagy and Predicts a Poor Prognosis in Lung Cancer Cases | Full Text | References | PDF (8 MB) | EPUB
  • 107 Views
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Article
MDM2-C Functions as an E3 Ubiquitin Ligase
Jun Yeob Kim, Rusia Lee, Gu Xiao, Dominique Forbes & Jill Bargonetti
Pages: 7715-7724
Published online: 24 Aug 2020
AbstractforMDM2-C Functions as an E3 Ubiquitin Ligase | Full Text | References | PDF (3.9 MB) | EPUB
  • 75 Views
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Article
Knockdown of Long Non-Coding RNA HOTAIR Suppresses Cisplatin Resistance, Cell Proliferation, Migration and Invasion of DDP-Resistant NSCLC Cells by Targeting miR-149-5p/Doublecortin-Like Kinase 1 Axis
Yiyi Zhan, Kahaerjiang Abuduwaili, Xiuli Wang, Yanli Shen, Saiteer Nuerlan & Chunling Liu
Pages: 7725-7737
Published online: 24 Aug 2020
AbstractforKnockdown of Long Non-Coding RNA HOTAIR Suppresses Cisplatin Resistance, Cell Proliferation, Migration and Invasion of DDP-Resistant NSCLC Cells by Targeting miR-149-5p/Doublecortin-Like Kinase 1 Axis | Full Text | References | PDF (6.4 MB) | EPUB
  • 94 Views
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Article
Exosomal Circ-ZNF652 Promotes Cell Proliferation, Migration, Invasion and Glycolysis in Hepatocellular Carcinoma via miR-29a-3p/GUCD1 Axis
Yuhui Li, Hongliang Zang, Xue Zhang & Guomin Huang
Pages: 7739-7751
Published online: 24 Aug 2020
AbstractforExosomal Circ-ZNF652 Promotes Cell Proliferation, Migration, Invasion and Glycolysis in Hepatocellular Carcinoma via miR-29a-3p/GUCD1 Axis | Full Text | References | PDF (8 MB) | EPUB
  • 89 Views
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Article
lncRNA PART1 Promotes Breast Cancer Cell Progression by Directly Targeting miR-4516
Zhuo Wang & Ruqing Xu
Pages: 7753-7760
Published online: 24 Aug 2020
AbstractforlncRNA PART1 Promotes Breast Cancer Cell Progression by Directly Targeting miR-4516 | Full Text | References | PDF (5 MB) | EPUB
  • 91 Views
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Article
Added Value of Biparametric MRI and TRUS-Guided Systematic Biopsies to Clinical Parameters in Predicting Adverse Pathology in Prostate Cancer
Hailang Liu, Kun Tang, Ding Xia, Xinguang Wang, Wei Zhu, Liang Wang, Weimin Yang, Ejun Peng & Zhiqiang Chen
Pages: 7761-7770
Published online: 24 Aug 2020
AbstractforAdded Value of Biparametric MRI and TRUS-Guided Systematic Biopsies to Clinical Parameters in Predicting Adverse Pathology in Prostate Cancer | Full Text | References | PDF (2.2 MB) | EPUB
  • 55 Views
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Article
Development and Validation of a Prognostic Nomogram to Predict the Long-Time Prognosis in Non-B, Non-C Hepatocellular Carcinoma
Kongying Lin, Qizhen Huang, Yuting Huo, Jianxing Zeng, Zongren Ding, Pengfei Guo, Zhenwei Chen, Yongyi Zeng & Jingfeng Liu
Pages: 7771-7781
Published online: 24 Aug 2020
AbstractforDevelopment and Validation of a Prognostic Nomogram to Predict the Long-Time Prognosis in Non-B, Non-C Hepatocellular Carcinoma | Full Text | References | PDF (3 MB) | EPUB
  • 72 Views
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Article
Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo
Hongliang Zang, Yuhui Li, Xue Zhang & Guomin Huang
Pages: 7783-7795
Published online: 25 Aug 2020
AbstractforBlocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo | Full Text | References | PDF (7.5 MB) | EPUB
  • 73 Views
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Article
Surgical and Conservative Management of Malignant Bowel Obstruction: Outcome and Prognostic Factors
Kaiying Yu, Lihui Liu, Xiaowei Zhang, Zhanzhi Zhang, Benqiang Rao, Yongbing Chen, Suyun Li & Hanping Shi
Pages: 7797-7803
Published online: 24 Aug 2020
AbstractforSurgical and Conservative Management of Malignant Bowel Obstruction: Outcome and Prognostic Factors | Full Text | References | PDF (289.3 KB) | EPUB
  • 174 Views
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Article
Long Non-Coding RNA TRPM2-AS Promotes Cell Migration and Invasion by Serving as a ceRNA of miR-138 and Inducing SOX4-Mediated EMT in Laryngeal Squamous Cell Carcinoma
Ning Wang, Lei Wang & Xinliang Pan
Pages: 7805-7812
Published online: 25 Aug 2020
AbstractforLong Non-Coding RNA TRPM2-AS Promotes Cell Migration and Invasion by Serving as a ceRNA of miR-138 and Inducing SOX4-Mediated EMT in Laryngeal Squamous Cell Carcinoma | Full Text | References | PDF (3.9 MB) | EPUB
  • 79 Views
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Article
Effects of Surgery Combined with Chemoradiotherapy on Short- and Long-Term Outcomes of Early-Stage Nasopharyngeal Carcinoma
Jing-Jin Weng, Jia-Zhang Wei, Min Li, Shao-Jie Zhang, Yun-Zhong Wei, Han-Wei Wang, Dan-Xue Qin, Jin-Long Lu, He Jiang & Shen-Hong Qu
Pages: 7813-7826
Published online: 25 Aug 2020
AbstractforEffects of Surgery Combined with Chemoradiotherapy on Short- and Long-Term Outcomes of Early-Stage Nasopharyngeal Carcinoma | Full Text | References | PDF (6.7 MB) | EPUB
  • 83 Views
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Article
PIF1 Affects the Proliferation and Apoptosis of Cervical Cancer Cells by Influencing TERT
Jiancai Wang, Xiaoyan Zhu, Pian Ying & Yingping Zhu
Pages: 7827-7835
Published online: 25 Aug 2020
AbstractforPIF1 Affects the Proliferation and Apoptosis of Cervical Cancer Cells by Influencing TERT | Full Text | References | PDF (4.1 MB) | EPUB
  • 107 Views
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Article
Aberrant Expression of NCAPG is Associated with Prognosis and Progression of Gastric Cancer
Ding-Ping Sun, Chih-Chan Lin, Shih-Ting Hung, Yi-Yu Kuang, You-Cheng Hseu, Chia-Lang Fang & Kai-Yuan Lin
Pages: 7837-7846
Published online: 25 Aug 2020
AbstractforAberrant Expression of NCAPG is Associated with Prognosis and Progression of Gastric Cancer | Full Text | References | PDF (5.2 MB) | EPUB
  • 83 Views
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Article
Long Non-Coding RNA KCNQ1OT1 Promotes Multidrug Resistance in Chordoma by Functioning as a Molecular Sponge of miR-27b-3p and Subsequently Increasing ATF2 Expression
Lei Li, Guohua Lv, Bing Wang & Hong Ma
Pages: 7847-7853
Published online: 25 Aug 2020
AbstractforLong Non-Coding RNA KCNQ1OT1 Promotes Multidrug Resistance in Chordoma by Functioning as a Molecular Sponge of miR-27b-3p and Subsequently Increasing ATF2 Expression | Full Text | References | PDF (3.7 MB) | EPUB
  • 61 Views
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Erratum

Correction
LncRNA PLAC 2 is Downregulated in Osteosarcoma and Regulates Cancer Cell Proliferation Through miR-93 [Erratum]
Page: 7855
Published online: 28 Aug 2020
CitationforLncRNA PLAC 2 is Downregulated in Osteosarcoma and Regulates Cancer Cell Proliferation Through miR-93 [Erratum] | Full Text | PDF (3 MB) | EPUB
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Original Research

Article
S1PR2 Knockdown Promotes Migration and Invasion in Multiple Myeloma Cells via NF-κB Activation
Meng Pang, Chunyuan Li, Dong Zheng, Ying Wang, Jing Wang, Weilong Zhang, Fang Li & Hongmei Jing
Pages: 7857-7865
Published online: 26 Aug 2020
AbstractforS1PR2 Knockdown Promotes Migration and Invasion in Multiple Myeloma Cells via NF-κB Activation | Full Text | References | PDF (3.2 MB) | EPUB
  • 92 Views
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Article
Onco-Metabolic Surgery: A Combined Approach to Gastric Cancer and Hypertension
Dong Peng, Yu-Xi Cheng, Wei Tao, Ying-Ying Zou, Kun Qian & Wei Zhang
Pages: 7867-7873
Published online: 26 Aug 2020
AbstractforOnco-Metabolic Surgery: A Combined Approach to Gastric Cancer and Hypertension | Full Text | References | PDF (1.1 MB) | EPUB
  • 150 Views
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Article
Nodal Involvement Pattern in Clinical Stage IA Non-Small Cell Lung Cancer According to Tumor Location
Shushi Meng, Ganwei Liu, Shaodong Wang, Fan Yang & Jun Wang
Pages: 7875-7880
Published online: 26 Aug 2020
AbstractforNodal Involvement Pattern in Clinical Stage IA Non-Small Cell Lung Cancer According to Tumor Location | Full Text | References | PDF (353.7 KB) | EPUB
  • 73 Views
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Open Access
Article
A Novel Epitope Quality-Based Immune Escape Mechanism Reveals Patient’s Suitability for Immune Checkpoint Inhibition
Michael Wessolly, Susann Stephan-Falkenau, Anna Streubel, Robert Werner, Sabrina Borchert, Sergej Griff, Elena Mairinger, Robert F H Walter, Torsten Bauer, Wilfried E E Eberhardt, Torsten G Blum, Kurt W Schmid, Jens Kollmeier, Thomas Mairinger & Fabian D Mairinger
Pages: 7881-7890
Published online: 26 Aug 2020
AbstractforA Novel Epitope Quality-Based Immune Escape Mechanism Reveals Patient’s Suitability for Immune Checkpoint Inhibition | Full Text | References | PDF (641.7 KB) | EPUB
  • 91 Views
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Review

Review Article
Evaluating Daratumumab in the Treatment of Multiple Myeloma: Safety, Efficacy and Place in Therapy
Danai Dima, Joshua Dower, Raymond L Comenzo & Cindy Varga
Pages: 7891-7903
Published online: 26 Aug 2020
AbstractforEvaluating Daratumumab in the Treatment of Multiple Myeloma: Safety, Efficacy and Place in Therapy | Full Text | References | PDF (953.6 KB) | EPUB
  • 352 Views
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Original Research

Article
Treatment of Synchronous Liver Metastases from Gastric Cancer: A Single-Center Study
Pengfei Yu, Yanqiang Zhang, Zeyao Ye, Xiangliu Chen, Ling Huang, Yian Du & Xiangdong Cheng
Pages: 7905-7911
Published online: 26 Aug 2020
AbstractforTreatment of Synchronous Liver Metastases from Gastric Cancer: A Single-Center Study | Full Text | References | PDF (1.4 MB) | EPUB
  • 85 Views
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Article
Effects of Hydroxytyrosol on Expression of Apoptotic Genes and Activity of Antioxidant Enzymes in LS180 Cells
Maryam Hormozi, Atena Salehi Marzijerani & Parastoo Baharvand
Pages: 7913-7919
Published online: 27 Aug 2020
AbstractforEffects of Hydroxytyrosol on Expression of Apoptotic Genes and Activity of Antioxidant Enzymes in LS180 Cells | Full Text | References | PDF (2 MB) | EPUB
  • 110 Views
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Article
LncRNA DCST1-AS1 Sponges miR-107 to Upregulate CDK6 in Cervical Squamous Cell Carcinoma
Zhigang Zhou & Na Xia
Pages: 7921-7928
Published online: 28 Aug 2020
AbstractforLncRNA DCST1-AS1 Sponges miR-107 to Upregulate CDK6 in Cervical Squamous Cell Carcinoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 58 Views
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Case Report

Case Report
A Case of a Huge Inferior Vena Cava Leiomyosarcoma: Precise Preoperative Evaluation with Gadobutrol-Enhanced MRI
Xiaoqi Zhou, Meng Wang, Shaoqiang Li, Huasong Cai, Lijian Liang, Zi-Ping Li, Shi-Ting Feng, Zhenpeng Peng & Xuehua Li
Pages: 7929-7939
Published online: 31 Aug 2020
AbstractforA Case of a Huge Inferior Vena Cava Leiomyosarcoma: Precise Preoperative Evaluation with Gadobutrol-Enhanced MRI | Full Text | References | PDF (2.3 MB) | EPUB
  • 91 Views
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Original Research

Article
LncRNA SNHG9 is Downregulated in Non-Small Cell Lung Cancer and Suppressed miR-21 Through Methylation to Promote Cell Proliferation
Dingxue Wang, Xiaoqing Cao, Yi Han & Daping Yu
Pages: 7941-7948
Published online: 31 Aug 2020
AbstractforLncRNA SNHG9 is Downregulated in Non-Small Cell Lung Cancer and Suppressed miR-21 Through Methylation to Promote Cell Proliferation | Full Text | References | PDF (3.2 MB) | EPUB
  • 78 Views
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Article
Long Noncoding RNA (lncRNA) MT1JP Suppresses Hepatocellular Carcinoma (HCC) in vitro
Wenhui Mo, Ying Dai, Jianqing Chen, Liwei Liang, Shuqi Xu & Xuanfu Xu
Pages: 7949-7960
Published online: 02 Sep 2020
AbstractforLong Noncoding RNA (lncRNA) MT1JP Suppresses Hepatocellular Carcinoma (HCC) in vitro | Full Text | References | PDF (8.3 MB) | EPUB
  • 58 Views
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Article
Exosome-Reversed Chemoresistance to Cisplatin in Non-Small Lung Cancer Through Transferring miR-613
Delong Li, Debin Meng & Rungui Niu
Pages: 7961-7972
Published online: 03 Sep 2020
AbstractforExosome-Reversed Chemoresistance to Cisplatin in Non-Small Lung Cancer Through Transferring miR-613 | Full Text | References | PDF (7.5 MB) | EPUB
  • 58 Views
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Review

Review Article
Gastric Signet Ring Cell Carcinoma: Current Management and Future Challenges
Yang Li, Zhikai Zhu, Fuhai Ma, Liyan Xue & Yantao Tian
Pages: 7973-7981
Published online: 03 Sep 2020
AbstractforGastric Signet Ring Cell Carcinoma: Current Management and Future Challenges | Full Text | References | PDF (683.5 KB) | EPUB
  • 346 Views
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Original Research

Article
Severe Fatigue is an Important Factor in the Prognosis of Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib
Xuan Qiu, Manjiang Li, Liqun Wu, Yang Xin, Siyu Mu, Tianxiang Li & Kangjian Song
Pages: 7983-7992
Published online: 04 Sep 2020
AbstractforSevere Fatigue is an Important Factor in the Prognosis of Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib | Full Text | References | PDF (2.3 MB) | EPUB
  • 61 Views
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Article
LncRNA PVT1 Regulates TRPS1 Expression in Breast Cancer by Sponging miR-543
Hongtao Wang, Yuanli Huang & Yuanrong Yang
Pages: 7993-8004
Published online: 04 Sep 2020
AbstractforLncRNA PVT1 Regulates TRPS1 Expression in Breast Cancer by Sponging miR-543 | Full Text | References | PDF (8.6 MB) | EPUB
  • 66 Views
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Article
Predictors of Prolonged Laparoscopic Radical Prostatectomy and the Creation of a Scoring System for the Duration
Shao-Hao Chen, Zhi-Bin Ke, Yu-Peng Wu, Dong-Ning Chen, Xiang Yu, Yu Chen, Yong Wei, Qing-Shui Zheng, Xue-Yi Xue & Ning Xu
Pages: 8005-8014
Published online: 04 Sep 2020
AbstractforPredictors of Prolonged Laparoscopic Radical Prostatectomy and the Creation of a Scoring System for the Duration | Full Text | References | PDF (1.3 MB) | EPUB
  • 55 Views
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Article
Moxibustion Enhances Chemotherapy of Breast Cancer by Affecting Tumor Microenvironment
Ning Xue, Xingli Fu, Yin Zhu, Nili Da & Jianbin Zhang
Pages: 8015-8022
Published online: 04 Sep 2020
AbstractforMoxibustion Enhances Chemotherapy of Breast Cancer by Affecting Tumor Microenvironment | Full Text | References | PDF (7.5 MB) | EPUB
  • 128 Views
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Article
Monoamine Oxidase A is a Major Mediator of Mitochondrial Homeostasis and Glycolysis in Gastric Cancer Progression
Ling Chen, Li Guo, Ziwen Sun, Guochun Yang, Jing Guo, Kai Chen, Ruixue Xiao, Xigui Yang & Lijun Sheng
Pages: 8023-8035
Published online: 04 Sep 2020
AbstractforMonoamine Oxidase A is a Major Mediator of Mitochondrial Homeostasis and Glycolysis in Gastric Cancer Progression | Full Text | References | PDF (6.6 MB) | EPUB
  • 109 Views
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Article
Predictive Factors and Long-Term Outcomes of Early Gastric Carcinomas in Patients with Non-Curative Resection by Endoscopic Submucosal Dissection
Ping Xu, Yun Wang, Yini Dang, Qin Huang, Jianhua Wang, Weifeng Zhang, Yifeng Zhang & Guoxin Zhang
Pages: 8037-8046
Published online: 04 Sep 2020
AbstractforPredictive Factors and Long-Term Outcomes of Early Gastric Carcinomas in Patients with Non-Curative Resection by Endoscopic Submucosal Dissection | Full Text | References | PDF (2.5 MB) | EPUB
  • 59 Views
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Article
Outcomes and Experiences of Child-Bearing Women with Nasopharyngeal Carcinoma
Liqin Ma, Fei Chen, Xiangquan Kong, Ting Xu, Zhaodong Fei, Weining Fang, Binyi Wang & Haixia Wu
Pages: 8047-8054
Published online: 04 Sep 2020
AbstractforOutcomes and Experiences of Child-Bearing Women with Nasopharyngeal Carcinoma | Full Text | References | PDF (1 MB) | EPUB
  • 69 Views
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Corrigendum

Correction
lncRNA TM4SF1-AS1 Activates the PI3K/AKT Signaling Pathway and Promotes the Migration and Invasion of Lung Cancer Cells [Corrigendum]
Page: 8055
Published online: 04 Sep 2020
CitationforlncRNA TM4SF1-AS1 Activates the PI3K/AKT Signaling Pathway and Promotes the Migration and Invasion of Lung Cancer Cells [Corrigendum] | Full Text | PDF (160.6 KB) | EPUB
  • 49 Views
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Original Research

Article
Predicting Lung Cancer Risk of Incidental Solid and Subsolid Pulmonary Nodules in Different Sizes
Rui Zhang, Panwen Tian, Bojiang Chen, Yongzhao Zhou & Weimin Li
Pages: 8057-8066
Published online: 04 Sep 2020
AbstractforPredicting Lung Cancer Risk of Incidental Solid and Subsolid Pulmonary Nodules in Different Sizes | Full Text | References | PDF (2.7 MB) | EPUB
  • 130 Views
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Article
miR-148a Affects Polarization of THP-1-Derived Macrophages and Reduces Recruitment of Tumor-Associated Macrophages via Targeting SIRPα
Donghe Ma, Yan Zhang, Guanghua Chen & Jia Yan
Pages: 8067-8077
Published online: 04 Sep 2020
AbstractformiR-148a Affects Polarization of THP-1-Derived Macrophages and Reduces Recruitment of Tumor-Associated Macrophages via Targeting SIRPα | Full Text | References | PDF (7.3 MB) | EPUB
  • 137 Views
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Corrigendum

Correction
The Efficacy and Safety of Apatinib in Advanced Synovial Sarcoma: A Case Series of Twenty-One Patients in One Single Institution [Corrigendum]
Page: 8079
Published online: 04 Sep 2020
CitationforThe Efficacy and Safety of Apatinib in Advanced Synovial Sarcoma: A Case Series of Twenty-One Patients in One Single Institution [Corrigendum] | Full Text | PDF (159.3 KB) | EPUB
  • 51 Views
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Original Research

Article
Oridonin Sensitizes Hepatocellular Carcinoma to the Anticancer Effect of Sorafenib by Targeting the Akt Pathway
Xuguang Li, Weirun Chen, Kaihang Liu, Sheng Zhang, Ru Yang, Kairui Liu, Dateng Li & Youxing Huang
Pages: 8081-8091
Published online: 07 Sep 2020
AbstractforOridonin Sensitizes Hepatocellular Carcinoma to the Anticancer Effect of Sorafenib by Targeting the Akt Pathway | Full Text | References | PDF (7.5 MB) | EPUB
  • 101 Views
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Article
CircFLNA Acts as a Sponge of miR-646 to Facilitate the Proliferation, Metastasis, Glycolysis, and Apoptosis Inhibition of Gastric Cancer by Targeting PFKFB2
Juan Qu, Jizhi Yang, Ming Chen, Rongna Wei & Jingjing Tian
Pages: 8093-8103
Published online: 07 Sep 2020
AbstractforCircFLNA Acts as a Sponge of miR-646 to Facilitate the Proliferation, Metastasis, Glycolysis, and Apoptosis Inhibition of Gastric Cancer by Targeting PFKFB2 | Full Text | References | PDF (7 MB) | EPUB
  • 63 Views
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Review

Review Article
PARP Inhibitors in Metastatic Prostate Cancer: Evidence to Date
Emily Nizialek & Emmanuel S Antonarakis
Pages: 8105-8114
Published online: 07 Sep 2020
AbstractforPARP Inhibitors in Metastatic Prostate Cancer: Evidence to Date | Full Text | References | PDF (305 KB) | EPUB
  • 381 Views
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Retraction

Retraction
Down-Regulation of CCL17 in Cancer-Associated Fibroblasts Inhibits Cell Migration and Invasion of Breast Cancer Through ERK1/2 Pathway [Retraction]
Page: 8115
Published online: 08 Sep 2020
CitationforDown-Regulation of CCL17 in Cancer-Associated Fibroblasts Inhibits Cell Migration and Invasion of Breast Cancer Through ERK1/2 Pathway [Retraction] | Full Text | PDF (167.8 KB) | EPUB
  • 42 Views
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Original Research

Article
LncRNA MCM3AP-AS1 Upregulates CDK4 by Sponging miR-545 to Suppress G1 Arrest in Colorectal Cancer
Xudong Ma, Jing Luo, Yi Zhang, Dali Sun & Yueying Lin
Pages: 8117-8124
Published online: 07 Sep 2020
AbstractforLncRNA MCM3AP-AS1 Upregulates CDK4 by Sponging miR-545 to Suppress G1 Arrest in Colorectal Cancer | Full Text | References | PDF (4.7 MB) | EPUB
  • 61 Views
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Article
Changes of Intestinal Microbiota in Ovarian Cancer Patients Treated with Surgery and Chemotherapy
Jinfei Tong, Xiao Zhang, Yunlong Fan, Lingfeng Chen, Xudong Ma, Hailan Yu, Jianqiong Li, Xiaojing Guan, Peiya Zhao & Jianhua Yang
Pages: 8125-8135
Published online: 07 Sep 2020
AbstractforChanges of Intestinal Microbiota in Ovarian Cancer Patients Treated with Surgery and Chemotherapy | Full Text | References | PDF (6.8 MB) | EPUB
  • 178 Views
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Article
RETRACTED ARTICLE: MiR-138-5p Inhibits the Proliferation of Gastric Cancer Cells by Targeting DEK
Wei Zhang, Kai Liao & Dongning Liu
Pages: 8137-8147
Published online: 08 Sep 2020
AbstractforRETRACTED ARTICLE: MiR-138-5p Inhibits the Proliferation of Gastric Cancer Cells by Targeting DEK | PDF (5.9 MB)
  • 20 Views
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Article
Prognostic Value of Fibrinogen and Lymphocyte Count in Intermediate and High Risk Gastrointestinal Stromal Tumors
Yinghao Guo, Jinqiang Liu, Wenming Zhang, Shuao Xiao, Gaozan Zheng, Shushang Liu, Man Guo, Hongwei Zhang & Fan Feng
Pages: 8149-8157
Published online: 08 Sep 2020
AbstractforPrognostic Value of Fibrinogen and Lymphocyte Count in Intermediate and High Risk Gastrointestinal Stromal Tumors | Full Text | References | PDF (2.4 MB) | EPUB
  • 55 Views
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Article
MicroRNA-431-5p Inhibits the Tumorigenesis of Osteosarcoma Through Targeting PANX3
Shengliang Sun, Lei Fu, Gen Wang, Jianli Wang & Liping Xu
Pages: 8159-8169
Published online: 08 Sep 2020
AbstractforMicroRNA-431-5p Inhibits the Tumorigenesis of Osteosarcoma Through Targeting PANX3 | Full Text | References | PDF (8.8 MB) | EPUB
  • 65 Views
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Article
Can Anti-Müllerian Hormone Be a Reliable Biomarker for Assessing Ovarian Function in Women Postchemotherapy?
Xiaolin Li, Sixuan Liu, Lisi Ma, Xuan Chen, Huaiyu Weng, Run Huang, Yang Yu & Xiangyun Zong
Pages: 8171-8181
Published online: 08 Sep 2020
AbstractforCan Anti-Müllerian Hormone Be a Reliable Biomarker for Assessing Ovarian Function in Women Postchemotherapy? | Full Text | References | PDF (3.3 MB) | EPUB
  • 94 Views
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Article
CircTTBK2 Contributes to the Progression of Glioma Through Regulating miR-145-5p/CPEB4 Axis
Yan Liu, Ruilong Li, Xuan Wang & Weidong Yang
Pages: 8183-8195
Published online: 08 Sep 2020
AbstractforCircTTBK2 Contributes to the Progression of Glioma Through Regulating miR-145-5p/CPEB4 Axis | Full Text | References | PDF (9 MB) | EPUB
  • 63 Views
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Article
Solid Nodule Appearance as a Predictor of Tumor Spread Through Air Spaces in Patients with Lung Adenocarcinoma: A Propensity Score Matching Study
Qingpeng Zeng, Bingzhi Wang, Jiagen Li, Jun Zhao, Yousheng Mao, Yushun Gao, Qi Xue, Shugeng Gao, Nan Sun & Jie He
Pages: 8197-8207
Published online: 08 Sep 2020
AbstractforSolid Nodule Appearance as a Predictor of Tumor Spread Through Air Spaces in Patients with Lung Adenocarcinoma: A Propensity Score Matching Study | Full Text | References | PDF (1.3 MB) | EPUB
  • 61 Views
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Article
Combination of Brachytherapy with Iodine-125 Seeds and Systemic Chemotherapy versus Systemic Chemotherapy Alone for Synchronous Extracranial Oligometastatic Non-Small Cell Lung Cancer
Huzi Li, Zhendong Duan, Cheng Zhao, Wenyan Fang, Yingjie Jia, Xiaojiang Li, Fanming Kong & Lujun Zhao
Pages: 8209-8220
Published online: 09 Sep 2020
AbstractforCombination of Brachytherapy with Iodine-125 Seeds and Systemic Chemotherapy versus Systemic Chemotherapy Alone for Synchronous Extracranial Oligometastatic Non-Small Cell Lung Cancer | Full Text | References | PDF (1.8 MB) | EPUB
  • 76 Views
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Article
Applicability of the Nutrition Risk Screening 2002 Combined with a Patient-Generated Subjective Global Assessment in Patients with Nasopharyngeal Carcinoma
Xiaoxian Pan, Caihong Wang, Rong Li, Li Su, Mingwei Zhang, Chuanshu Cai, Shiping Liu, Weijian Zhang, Jihong Song & Jinsheng Hong
Pages: 8221-8227
Published online: 09 Sep 2020
AbstractforApplicability of the Nutrition Risk Screening 2002 Combined with a Patient-Generated Subjective Global Assessment in Patients with Nasopharyngeal Carcinoma | Full Text | References | PDF (541.6 KB) | EPUB
  • 92 Views
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Article
Circular RNA hsa_circ_0003496 Contributes to Tumorigenesis and Chemoresistance in Osteosarcoma Through Targeting (microRNA) miR-370/Krüppel-Like Factor 12 Axis
Chaofan Xie, Guanzhao Liang, Yinfeng Xu & Erhu Lin
Pages: 8229-8240
Published online: 09 Sep 2020
AbstractforCircular RNA hsa_circ_0003496 Contributes to Tumorigenesis and Chemoresistance in Osteosarcoma Through Targeting (microRNA) miR-370/Krüppel-Like Factor 12 Axis | Full Text | References | PDF (7.9 MB) | EPUB
  • 101 Views
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Article
High Expression of Nuclear Transcription Factor-κB is Associated with Cisplatin Resistance and Prognosis for Ovarian Cancer
Yanyan Kan, Juntian Liu & Fangxuan Li
Pages: 8241-8252
Published online: 09 Sep 2020
AbstractforHigh Expression of Nuclear Transcription Factor-κB is Associated with Cisplatin Resistance and Prognosis for Ovarian Cancer | Full Text | References | PDF (3.5 MB) | EPUB
  • 66 Views
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Article
LncRNA GAS5 Regulates Osteosarcoma Cell Proliferation, Migration, and Invasion by Regulating RHOB via Sponging miR-663a
Xinyu Yao, Xianan Li, Yi Luo, Xuezheng Xu, Jianfan Liu & Jie Bu
Pages: 8253-8261
Published online: 09 Sep 2020
AbstractforLncRNA GAS5 Regulates Osteosarcoma Cell Proliferation, Migration, and Invasion by Regulating RHOB via Sponging miR-663a | Full Text | References | PDF (6.3 MB) | EPUB
  • 71 Views
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Article
Pickled Vegetables Intake Impacts the Metabolites for Gastric Cancer
Shuangfeng Yang, Yanping Lv, Chuancheng Wu, Baoying Liu, Zhixiong Shu & Yulan Lin
Pages: 8263-8273
Published online: 09 Sep 2020
AbstractforPickled Vegetables Intake Impacts the Metabolites for Gastric Cancer | Full Text | References | PDF (5.7 MB) | EPUB
  • 113 Views
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Article
Digital Image Analysis of CD8+ and CD3+ Tumor-Infiltrating Lymphocytes in Tongue Squamous Cell Carcinoma
Yenlin Huang, Chieh Lin, Huang-Kai Kao, Shao-Yu Hung, Hung-Ju Ko, Yu-Chen Huang, Yu-Liang Chang & Kai-Ping Chang
Pages: 8275-8285
Published online: 09 Sep 2020
AbstractforDigital Image Analysis of CD8+ and CD3+ Tumor-Infiltrating Lymphocytes in Tongue Squamous Cell Carcinoma | Full Text | References | PDF (2.2 MB) | EPUB
  • 117 Views
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Article
CircRNA Circ_0001721 Promotes the Progression of Osteosarcoma Through miR-372-3p/MAPK7 Axis
Yuanpeng Gao, Haixia Ma, Yan Gao, Kai Tao, Liyan Fu, Ruimin Ren, Xingui Hu, Min Kou, Bin Chen, Junjun Shi & Yunpeng Wen
Pages: 8287-8302
Published online: 11 Sep 2020
AbstractforCircRNA Circ_0001721 Promotes the Progression of Osteosarcoma Through miR-372-3p/MAPK7 Axis | Full Text | References | PDF (12.7 MB) | EPUB
  • 91 Views
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Article
Long Noncoding RNA SNHG7 Accelerates Proliferation, Migration and Invasion of Non-Small Cell Lung Cancer Cells by Suppressing miR-181a-5p Through AKT/mTOR Signaling Pathway
Liping Li, Dan Ye, Liang Liu, Xiaoju Li, Jun Liu, Shengtian Su, Wenjing Lu & Zhigao Yu
Pages: 8303-8312
Published online: 10 Sep 2020
AbstractforLong Noncoding RNA SNHG7 Accelerates Proliferation, Migration and Invasion of Non-Small Cell Lung Cancer Cells by Suppressing miR-181a-5p Through AKT/mTOR Signaling Pathway | Full Text | References | PDF (4.5 MB) | EPUB
  • 76 Views
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Article
Construction of Nomograms for Predicting Pathological Complete Response and Tumor Shrinkage Size in Breast Cancer
Shuai Yan, Wenjie Wang, Bifa Zhu, Xixi Pan, Xiaoyan Wu & Weiyang Tao
Pages: 8313-8323
Published online: 10 Sep 2020
AbstractforConstruction of Nomograms for Predicting Pathological Complete Response and Tumor Shrinkage Size in Breast Cancer | Full Text | References | PDF (2.2 MB) | EPUB
  • 87 Views
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Article
Identification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer
Fangdong Jiao, Hao Sun, Qingya Yang, Hui Sun, Zehua Wang, Ming Liu & Jun Chen
Pages: 8325-8339
Published online: 10 Sep 2020
AbstractforIdentification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer | Full Text | References | PDF (12.7 MB) | EPUB
  • 148 Views
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Article
Synergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications
Yusi Liu, Xue Song, Moli Wu, Jiao Wu & Jia Liu
Pages: 8341-8354
Published online: 11 Sep 2020
AbstractforSynergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications | Full Text | References | PDF (11.2 MB) | EPUB
  • 185 Views
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Article
Outcome and Optimal Treatment for Esthesioneuroblastoma in the Era of Intensity-Modulated Radiation Therapy: A Single-Center Experience
Tongxin Liu, Quanquan Sun, Weifeng Qin, Xiaozhong Chen & Qiaoying Hu
Pages: 8355-8362
Published online: 10 Sep 2020
AbstractforOutcome and Optimal Treatment for Esthesioneuroblastoma in the Era of Intensity-Modulated Radiation Therapy: A Single-Center Experience | Full Text | References | PDF (1.5 MB) | EPUB
  • 85 Views
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Article
RETRACTED ARTICLE: Long Non-Coding RNA DARS-AS1 Contributes to Prostate Cancer Progression Through Regulating the MicroRNA-628-5p/MTDH Axis
Haitao Fan, Junhui Hou, Siqing Liu, Zuomin Xiao & Jia Cui
Pages: 8363-8377
Published online: 10 Sep 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA DARS-AS1 Contributes to Prostate Cancer Progression Through Regulating the MicroRNA-628-5p/MTDH Axis | PDF (10.1 MB)
  • 17 Views
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Review

Review Article
Emerging Treatment Options for the Treatment of Metastatic Urothelial Cancer: Therapeutic Potential of Enfortumab Vedotin
Rohit K Jain, William Paul Skelton IV & Jingsong Zhang
Pages: 8379-8386
Published online: 11 Sep 2020
AbstractforEmerging Treatment Options for the Treatment of Metastatic Urothelial Cancer: Therapeutic Potential of Enfortumab Vedotin | Full Text | References | PDF (276.8 KB) | EPUB
  • 157 Views
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Original Research

Article
Oridonin Induces Apoptosis of Laryngeal Carcinoma via Endoplasmic Reticulum Stress
Bo Kou, Yang Yang, Yin-E Bai, Yu-Han Shi, Rui-Xia Gao, Fang-Li Yang, Shao-Qiang Zhang & Wei Liu
Pages: 8387-8396
Published online: 11 Sep 2020
AbstractforOridonin Induces Apoptosis of Laryngeal Carcinoma via Endoplasmic Reticulum Stress | Full Text | References | PDF (5 MB) | EPUB
  • 78 Views
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Article
Effects of Chemotherapy on Serum Lipids in Chinese Postoperative Breast Cancer Patients
Qi Lu, Xian Wu, Yanhui Zhu, Junzhe Yang, Xingmeng Wang, Chaoran Ye, Ruyu Cai, Kai Zhang, Tingyu Xu, Bing Wang, Jordee S Veeramootoo, Tiansong Xia & Xiaoan Liu
Pages: 8397-8408
Published online: 11 Sep 2020
AbstractforEffects of Chemotherapy on Serum Lipids in Chinese Postoperative Breast Cancer Patients | Full Text | References | PDF (3.7 MB) | EPUB
  • 106 Views
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Corrigendum

Correction
Large Scale, Multicenter, Prospective Study of Apatinib in Advanced Gastric Cancer: A Real-World Study from China [Corrigendum]
Page: 8409
Published online: 11 Sep 2020
CitationforLarge Scale, Multicenter, Prospective Study of Apatinib in Advanced Gastric Cancer: A Real-World Study from China [Corrigendum] | Full Text | PDF (168.5 KB) | EPUB
  • 57 Views
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Retraction

Retraction
Clinical Significance of Down-Regulated CD70 and CD27 Expression in Poor Prognosis of Esophageal Squamous Cell Carcinoma [Retraction]
Page: 8411
Published online: 11 Sep 2020
CitationforClinical Significance of Down-Regulated CD70 and CD27 Expression in Poor Prognosis of Esophageal Squamous Cell Carcinoma [Retraction] | Full Text | PDF (166.4 KB) | EPUB
  • 55 Views
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Original Research

Article
Ursolic Acid Protects Against Proliferation and Inflammatory Response in LPS-Treated Gastric Tumour Model and Cells by Inhibiting NLRP3 Inflammasome Activation
Zixi Chen, Qiaoli Liu, Zhaowei Zhu, Fenfen Xiang, Mengzhe Zhang, Rong Wu & Xiangdong Kang
Pages: 8413-8424
Published online: 11 Sep 2020
AbstractforUrsolic Acid Protects Against Proliferation and Inflammatory Response in LPS-Treated Gastric Tumour Model and Cells by Inhibiting NLRP3 Inflammasome Activation | Full Text | References | PDF (7.3 MB) | EPUB
  • 77 Views
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Article
Evaluation of Alterations to Bile Ducts and Laboratory Values During the First 3 Months After Irreversible Electroporation of Malignant Hepatic Tumors
Wolf Bäumler, Mareike Sebald, Ingo Einspieler, Andreas Schicho, Jan Schaible, Philipp Wiggermann, Marco Dollinger, Christian Stroszczynski & Lukas Philipp Beyer
Pages: 8425-8433
Published online: 14 Sep 2020
AbstractforEvaluation of Alterations to Bile Ducts and Laboratory Values During the First 3 Months After Irreversible Electroporation of Malignant Hepatic Tumors | Full Text | References | PDF (483.5 KB) | EPUB
  • 65 Views
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Review

Review Article
The Significance of CXCL1 and CXCL8 as Well as Their Specific Receptors in Colorectal Cancer
Marta Łukaszewicz-Zając, Sara Pączek, Piotr Mroczko & Agnieszka Kulczyńska-Przybik
Pages: 8435-8443
Published online: 14 Sep 2020
AbstractforThe Significance of CXCL1 and CXCL8 as Well as Their Specific Receptors in Colorectal Cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 148 Views
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Original Research

Article
The Clinical Characteristics and Prognosis of Different Age Patients with Lung Cancer
Xiaorao Chen, Xiaoling Han, Honglian Zhou, Yahai Liang, Zhong Huang, Shujun Li, Yanming Lin, Xiaobi Huang, Jiancong Wu, Wenmei Su, Zhennan Lai & Zhixiong Yang
Pages: 8445-8450
Published online: 14 Sep 2020
AbstractforThe Clinical Characteristics and Prognosis of Different Age Patients with Lung Cancer | Full Text | References | PDF (285.4 KB) | EPUB
  • 77 Views
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Article
The Association Between Illness Acceptance and Quality of Life in Women with Breast Cancer
Beata Jankowska-Polańska, Natalia Świątoniowska-Lonc, Edyta Ośmiałowska, Aneta Gałka & Mariusz Chabowski
Pages: 8451-8464
Published online: 14 Sep 2020
AbstractforThe Association Between Illness Acceptance and Quality of Life in Women with Breast Cancer | Full Text | References | PDF (385.9 KB) | EPUB
  • 286 Views
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Article
RETRACTED ARTICLE: Circ_0007031 Serves as a Sponge of miR-760 to Regulate the Growth and Chemoradiotherapy Resistance of Colorectal Cancer via Regulating DCP1A
Yuanyuan Wang, Hua Wang, Jian Zhang, Zhifen Chu, Pu Liu, Xing Zhang, Chao Li & Xiaosong Gu
Pages: 8465-8479
Published online: 14 Sep 2020
AbstractforRETRACTED ARTICLE: Circ_0007031 Serves as a Sponge of miR-760 to Regulate the Growth and Chemoradiotherapy Resistance of Colorectal Cancer via Regulating DCP1A | PDF (10.2 MB)
  • 28 Views
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Article
Prognostic Role of Prothrombin Time Activity, Prothrombin Time, Albumin/Globulin Ratio, Platelets, Sex, and Fibrinogen in Predicting Recurrence-Free Survival Time of Renal Cancer
Zichen Bian, Jialin Meng, Qingsong Niu, Xiaoyan Jin, Jinian Wang, Xingliang Feng, Hong Che, Jun Zhou, Li Zhang, Meng Zhang & Chaozhao Liang
Pages: 8481-8490
Published online: 15 Sep 2020
AbstractforPrognostic Role of Prothrombin Time Activity, Prothrombin Time, Albumin/Globulin Ratio, Platelets, Sex, and Fibrinogen in Predicting Recurrence-Free Survival Time of Renal Cancer | Full Text | References | PDF (842.5 KB) | EPUB
  • 101 Views
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Article
A Retrospective Study of Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer
Yajing Wang, Kang He, Zhaofei Zhou, Yuejiao Zhong, Gang Li & Jianwei Lu
Pages: 8491-8496
Published online: 15 Sep 2020
AbstractforA Retrospective Study of Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer | Full Text | References | PDF (770 KB) | EPUB
  • 73 Views
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Article
Predicting Prognosis and Adverse Events by Hematologic Markers in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma Treated with Neoadjuvant Chemoradiotherapy
Guoxin Cai, Jinming Yu & Xue Meng
Pages: 8497-8507
Published online: 15 Sep 2020
AbstractforPredicting Prognosis and Adverse Events by Hematologic Markers in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma Treated with Neoadjuvant Chemoradiotherapy | Full Text | References | PDF (2.8 MB) | EPUB
  • 102 Views
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Article
Abnormal Activations of Super-Enhancers Enhance the Carcinogenicity in Lung Adenocarcinoma
Jianlong Zhou, Dingxue Wang, Dongxin Tang & Wenhua Huang
Pages: 8509-8518
Published online: 15 Sep 2020
AbstractforAbnormal Activations of Super-Enhancers Enhance the Carcinogenicity in Lung Adenocarcinoma | Full Text | References | PDF (6.6 MB) | EPUB
  • 84 Views
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Article
Acceptance of Human Papillomavirus Vaccination and Associated Factors Among Parents of Daughters in Gondar Town, Northwest Ethiopia
Tsigereda Alene, Asmamaw Atnafu, Zeleke Abebaw Mekonnen & Amare Minyihun
Pages: 8519-8526
Published online: 16 Sep 2020
AbstractforAcceptance of Human Papillomavirus Vaccination and Associated Factors Among Parents of Daughters in Gondar Town, Northwest Ethiopia | Full Text | References | PDF (281.9 KB) | EPUB
  • 531 Views
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Article
Depth of Response and Early Tumor Shrinkage for Predicting Clinical Outcomes in HER2-Positive Metastatic Breast Cancer Treated with Trastuzumab
Yi-Qun Che, Yue Zhang, Kai-Ping Ou, Di Wang, Di Shen, Hui-Ying Liu & Yang Luo
Pages: 8527-8534
Published online: 16 Sep 2020
AbstractforDepth of Response and Early Tumor Shrinkage for Predicting Clinical Outcomes in HER2-Positive Metastatic Breast Cancer Treated with Trastuzumab | Full Text | References | PDF (996.8 KB) | EPUB
  • 64 Views
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Article
RETRACTED ARTICLE: LncRNA PTCSC3 and lncRNA HULC Negatively Affect Each Other to Regulate Cancer Cell Invasion and Migration in Gastric Cancer
Yi Cai, Yang Li, Bin Sun, Hugen Wang, Weiping Zhang, Yuanyuan Zhao, Haodong Zhao, Jianlin Zhang, Jianming Xu & Yalei Wang
Pages: 8535-8543
Published online: 16 Sep 2020
AbstractforRETRACTED ARTICLE: LncRNA PTCSC3 and lncRNA HULC Negatively Affect Each Other to Regulate Cancer Cell Invasion and Migration in Gastric Cancer | PDF (6.2 MB)
  • 15 Views
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Review

Review Article
Preventative and Therapeutic Effects of Metformin in Gastric Cancer: A New Contribution of an Old Friend
Jing Zhang, Liping Wen, Quan Zhou, Kuifeng He & Lisong Teng
Pages: 8545-8554
Published online: 16 Sep 2020
AbstractforPreventative and Therapeutic Effects of Metformin in Gastric Cancer: A New Contribution of an Old Friend | Full Text | References | PDF (3.1 MB) | EPUB
  • 93 Views
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Original Research

Article
Preoperative Fibrinogen-Albumin Ratio Index (FARI) is a Reliable Prognosis and Chemoradiotherapy Sensitivity Predictor in Locally Advanced Rectal Cancer Patients Undergoing Radical Surgery Following Neoadjuvant Chemoradiotherapy
Siyi Lu, Zhenzhen Liu, Xin Zhou, Bingyan Wang, Fei Li, Yanpeng Ma, Wendong Wang, Junren Ma, Yuxia Wang, Hao Wang & Wei Fu
Pages: 8555-8568
Published online: 17 Sep 2020
AbstractforPreoperative Fibrinogen-Albumin Ratio Index (FARI) is a Reliable Prognosis and Chemoradiotherapy Sensitivity Predictor in Locally Advanced Rectal Cancer Patients Undergoing Radical Surgery Following Neoadjuvant Chemoradiotherapy | Full Text | References | PDF (4.6 MB) | EPUB
  • 97 Views
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Article
The miRNA, miR-125b, Inhibited Invasion and Metastasis of Gastric-Cancer Cells by Triggering the STAT3 Signaling Pathway
Xiangqian Xu, Zhongqin Dang, Junping Zhang, Yingpu Feng & Zheng Wei
Pages: 8569-8580
Published online: 17 Sep 2020
AbstractforThe miRNA, miR-125b, Inhibited Invasion and Metastasis of Gastric-Cancer Cells by Triggering the STAT3 Signaling Pathway | Full Text | References | PDF (9.7 MB) | EPUB
  • 76 Views
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Article
The Pattern of Cervical Lymph Node Metastasis and Risk Factors of Retropharyngeal Lymph Node Metastasis Based on Magnetic Resonance Imaging in Different Sites of Hypopharyngeal Carcinoma
Huili Wang, Runye Wu, Xiaodong Huang, Yuan Qu, Kai Wang, Qingfeng Liu, Xuesong Chen, Ye Zhang, Shiping Zhang, Jianping Xiao, Junlin Yi, Guozhen Xu, Li Gao & Jingwei Luo
Pages: 8581-8587
Published online: 18 Sep 2020
AbstractforThe Pattern of Cervical Lymph Node Metastasis and Risk Factors of Retropharyngeal Lymph Node Metastasis Based on Magnetic Resonance Imaging in Different Sites of Hypopharyngeal Carcinoma | Full Text | References | PDF (264.2 KB) | EPUB
  • 68 Views
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Article
Combination of Haemoglobin and Prognostic Nutritional Index Predicts the Prognosis of Postoperative Radiotherapy for Esophageal Squamous Cell Carcinoma
Bei Wang, Xiao-wen Jiang, Da-long Tian, Ning Zhou & Wei Geng
Pages: 8589-8597
Published online: 18 Sep 2020
AbstractforCombination of Haemoglobin and Prognostic Nutritional Index Predicts the Prognosis of Postoperative Radiotherapy for Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (427.3 KB) | EPUB
  • 120 Views
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Article
Cancer Incidence and Distribution at a Tertiary Care Hospital in Somalia from 2017 to 2020: An Initial Report of 1306 Cases
Mehmet Tahtabasi, Ismail Mohamud Abdullahi, Mustafa Kalayci, Ismail Gedi Ibrahim & Sadettin Er
Pages: 8599-8611
Published online: 28 Sep 2020
AbstractforCancer Incidence and Distribution at a Tertiary Care Hospital in Somalia from 2017 to 2020: An Initial Report of 1306 Cases | Full Text | References | PDF (3.3 MB) | EPUB
  • 457 Views
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Article
Comparison of Prognosis Between Juvenile and Adult Nasopharyngeal Carcinoma: A Propensity Score-Matched Analysis
Chuanben Chen, Qinyan Chen, Yuanji Xu, Wei Zheng, Zhizhong Lin, Zijie Wu, Wangzhong Ye, Xinyi Huang, Xiurong Lin & Penggang Bai
Pages: 8613-8621
Published online: 18 Sep 2020
AbstractforComparison of Prognosis Between Juvenile and Adult Nasopharyngeal Carcinoma: A Propensity Score-Matched Analysis | Full Text | References | PDF (2.7 MB) | EPUB
  • 58 Views
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Article
PACE4 Expression is a Novel Independent Prognostic Factor in Nasopharyngeal Carcinoma
Yunen Lin, Huidong Long, Xiaojun Tan, Donghui Zhang & Liwen Jiang
Pages: 8623-8629
Published online: 18 Sep 2020
AbstractforPACE4 Expression is a Novel Independent Prognostic Factor in Nasopharyngeal Carcinoma | Full Text | References | PDF (1.4 MB) | EPUB
  • 71 Views
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Article
Downregulation of Immortalization-Upregulated Protein Suppresses the Progression of Breast Cancer Cell Lines by Regulating Epithelial–Mesenchymal Transition
Jialiang Wen, Lizhi Lin, Bangyi Lin, Erjie Xia, Jinmiao Qu & Ouchen Wang
Pages: 8631-8642
Published online: 18 Sep 2020
AbstractforDownregulation of Immortalization-Upregulated Protein Suppresses the Progression of Breast Cancer Cell Lines by Regulating Epithelial–Mesenchymal Transition | Full Text | References | PDF (6.7 MB) | EPUB
  • 68 Views
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Article
Relationship Between Fibrinogen to Albumin Ratio and Prognosis of Gastrointestinal Stromal Tumors: A Retrospective Cohort Study
Rui Li, Shibo Song, Xiuwen He, Xiaolei Shi, Zhen Sun, Zhe Li & Jinghai Song
Pages: 8643-8651
Published online: 18 Sep 2020
AbstractforRelationship Between Fibrinogen to Albumin Ratio and Prognosis of Gastrointestinal Stromal Tumors: A Retrospective Cohort Study | Full Text | References | PDF (1.9 MB) | EPUB
  • 77 Views
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Article
Concomitant Mutations in EGFR 19Del/L858R Mutation and Their Association with Response to EGFR-TKIs in NSCLC Patients
Hengrui Liang, Caichen Li, Yi Zhao, Shen Zhao, Jun Huang, Xiuyu Cai, Bo Cheng, Shan Xiong, Jianfu Li, Wei Wang, Changbin Zhu, Weiwei Li, Jianxing He & Wenhua Liang
Pages: 8653-8662
Published online: 18 Sep 2020
AbstractforConcomitant Mutations in EGFR 19Del/L858R Mutation and Their Association with Response to EGFR-TKIs in NSCLC Patients | Full Text | References | PDF (4.6 MB) | EPUB
  • 210 Views
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Article
Downregulation of circRNA_0000285 Suppresses Cervical Cancer Development by Regulating miR197-3p–ELK1 Axis
Wenmin Zhang & Suping Zhang
Pages: 8663-8674
Published online: 18 Sep 2020
AbstractforDownregulation of circRNA_0000285 Suppresses Cervical Cancer Development by Regulating miR197-3p–ELK1 Axis | Full Text | References | PDF (7.3 MB) | EPUB
  • 74 Views
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Article
Radiotherapy for Cervical Cancer in Patients with Systemic Lupus Erythematosus
Jiabin Ma, Weiping Wang, Jing Shen, Xiaorong Hou, Xin Lian, Junfang Yan, Shuai Sun, Zheng Miao, Qingyu Meng, Ke Hu & Fuquan Zhang
Pages: 8675-8683
Published online: 21 Sep 2020
AbstractforRadiotherapy for Cervical Cancer in Patients with Systemic Lupus Erythematosus | Full Text | References | PDF (295.5 KB) | EPUB
  • 111 Views
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Article
miR-133a-3p Regulates Hepatocellular Carcinoma Progression Through Targeting CORO1C
Shuangxi Han, Xuemei Ding, Shaohong Wang, Li Xu, Wenxiao Li & Wenbing Sun
Pages: 8685-8693
Published online: 21 Sep 2020
AbstractformiR-133a-3p Regulates Hepatocellular Carcinoma Progression Through Targeting CORO1C | Full Text | References | PDF (6.9 MB) | EPUB
  • 71 Views
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Article
The Predictive Value of MLR for Radiation Pneumonia During Radiotherapy of Thoracic Tumor Patients
Ya Gao, Xinyi Wu, Yunhao Li, Yifei Li, Qingyu Zhou, Qiongqiong Wang, Chaoyi Wei, Deli Shi, Congying Xie & Huanle Pan
Pages: 8695-8701
Published online: 21 Sep 2020
AbstractforThe Predictive Value of MLR for Radiation Pneumonia During Radiotherapy of Thoracic Tumor Patients | Full Text | References | PDF (1.1 MB) | EPUB
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Review

Review Article
Progress in Research on Colorectal Cancer-Related Microorganisms and Metabolites
Shuwen Han, Jing Zhuang, Yinhang Wu, Wei Wu & Xi Yang
Pages: 8703-8720
Published online: 21 Sep 2020
AbstractforProgress in Research on Colorectal Cancer-Related Microorganisms and Metabolites | Full Text | References | PDF (4 MB) | EPUB
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Original Research

Article
Prognostic Significance of Preoperative Gamma-Glutamyltransferase to Alkaline Phosphatase Ratio in Hepatocellular Carcinoma Patients with Curative Liver Resection: A Retrospective Cohort Study
Guoqing Ouyang, Guangdong Pan, Yongrong Wu, Qiang Liu, Wuchang Lu & Xiang Chen
Pages: 8721-8732
Published online: 21 Sep 2020
AbstractforPrognostic Significance of Preoperative Gamma-Glutamyltransferase to Alkaline Phosphatase Ratio in Hepatocellular Carcinoma Patients with Curative Liver Resection: A Retrospective Cohort Study | Full Text | References | PDF (4 MB) | EPUB
  • 72 Views
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Article
Adipose Mesenchymal Stem Cell-Derived Exosomal microRNA-1236 Reduces Resistance of Breast Cancer Cells to Cisplatin by Suppressing SLC9A1 and the Wnt/β-Catenin Signaling
Zhongming Jia, Huamin Zhu, Hongguang Sun, Yitong Hua, Guoqiang Zhang, Jingru Jiang & Xiaohong Wang
Pages: 8733-8744
Published online: 22 Sep 2020
AbstractforAdipose Mesenchymal Stem Cell-Derived Exosomal microRNA-1236 Reduces Resistance of Breast Cancer Cells to Cisplatin by Suppressing SLC9A1 and the Wnt/β-Catenin Signaling | Full Text | References | PDF (6 MB) | EPUB
  • 173 Views
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Article
Knockdown of MIR4435-2HG Suppresses the Proliferation, Migration and Invasion of Cervical Cancer Cells via Regulating the miR-128-3p/MSI2 Axis in vitro
Ruijing Wang, Lun Liu, Jinwen Jiao & Dongmei Gao
Pages: 8745-8756
Published online: 22 Sep 2020
AbstractforKnockdown of MIR4435-2HG Suppresses the Proliferation, Migration and Invasion of Cervical Cancer Cells via Regulating the miR-128-3p/MSI2 Axis in vitro | Full Text | References | PDF (7 MB) | EPUB
  • 94 Views
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Article
Knockdown of LINC02471 Inhibits Papillary Thyroid Carcinoma Cell Invasion and Metastasis by Targeting miR-375
Dongfang Chen, Zhongke Huang, Yanli Ning & Cen Lou
Pages: 8757-8771
Published online: 22 Sep 2020
AbstractforKnockdown of LINC02471 Inhibits Papillary Thyroid Carcinoma Cell Invasion and Metastasis by Targeting miR-375 | Full Text | References | PDF (12.9 MB) | EPUB
  • 69 Views
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Article
Knockdown of PVT1 Suppresses Colorectal Cancer Progression by Regulating MiR-106b-5p/FJX1 Axis
Fang Liu, Rong Wu, Lina Guan & Xuegui Tang
Pages: 8773-8785
Published online: 22 Sep 2020
AbstractforKnockdown of PVT1 Suppresses Colorectal Cancer Progression by Regulating MiR-106b-5p/FJX1 Axis | Full Text | References | PDF (7.8 MB) | EPUB
  • 66 Views
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Article
Value of Ultrasound Combined with Immunohistochemistry Evaluation of Central Lymph Node Metastasis for the Prognosis of Papillary Thyroid Carcinoma
Xiaohua Yao, Ying Meng, Runsheng Guo, Guofeng Lu, Lin Jin, Yingchun Wang & Debin Yang
Pages: 8787-8799
Published online: 22 Sep 2020
AbstractforValue of Ultrasound Combined with Immunohistochemistry Evaluation of Central Lymph Node Metastasis for the Prognosis of Papillary Thyroid Carcinoma | Full Text | References | PDF (1.7 MB) | EPUB
  • 78 Views
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Article
The Anti-Apoptotic Role of EBV-LMP1 in Lymphoma Cells
Mei Zeng, Yuhua Chen, Xintao Jia & Yan Liu
Pages: 8801-8811
Published online: 22 Sep 2020
AbstractforThe Anti-Apoptotic Role of EBV-LMP1 in Lymphoma Cells | Full Text | References | PDF (8.4 MB) | EPUB
  • 108 Views
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Article
Diagnosis Value of Combined Detection of Serum SF, CEA and CRP in Non-Small Cell Lung Cancer
Jing Zhou, Xin Diao, Shengyu Wang & Yang Yao
Pages: 8813-8819
Published online: 22 Sep 2020
AbstractforDiagnosis Value of Combined Detection of Serum SF, CEA and CRP in Non-Small Cell Lung Cancer | Full Text | References | PDF (287.7 KB) | EPUB
  • 124 Views
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Article
Acute Toxicities and Prognosis of Elderly Patients with Nasopharyngeal Carcinoma After Intensity-Modulated Radiotherapy: Prediction with Nomogram
Yu Liang, Kai-hua Chen, Jie Yang, Jing Zhang, Ru-rong Peng, Song Qu, Ling Li & Xiao-dong Zhu
Pages: 8821-8832
Published online: 22 Sep 2020
AbstractforAcute Toxicities and Prognosis of Elderly Patients with Nasopharyngeal Carcinoma After Intensity-Modulated Radiotherapy: Prediction with Nomogram | Full Text | References | PDF (2 MB) | EPUB
  • 66 Views
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Article
Long Non-Coding RNA GAS5 Suppresses Tumor Progression and Enhances the Radiosensitivity of Prostate Cancer Through the miR-320a/RAB21 Axis
Xiulong Ma, Zhongwei Wang, Hongtao Ren, Xing Bao, Yang Zhang, Baofeng Wang & Dongli Ruan
Pages: 8833-8845
Published online: 22 Sep 2020
AbstractforLong Non-Coding RNA GAS5 Suppresses Tumor Progression and Enhances the Radiosensitivity of Prostate Cancer Through the miR-320a/RAB21 Axis | Full Text | References | PDF (8.1 MB) | EPUB
  • 78 Views
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Review

Review Article
The Role of Prefoldin and Its Subunits in Tumors and Their Application Prospects in Nanomedicine
Shao-jian Mo, Hai-Chao Zhao, Yan-zhang Tian & Hao-Liang Zhao
Pages: 8847-8856
Published online: 23 Sep 2020
AbstractforThe Role of Prefoldin and Its Subunits in Tumors and Their Application Prospects in Nanomedicine | Full Text | References | PDF (1.5 MB) | EPUB
  • 105 Views
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Original Research

Article
CELSR1 Acts as an Oncogene Regulated by miR-199a-5p in Glioma
Guang Wang, Yong Li, Dongxia Zhang, Songtao Zhao, Qiong Zhang, Chao Luo, Xiaochuan Sun & Bingqian Zhang
Pages: 8857-8865
Published online: 23 Sep 2020
AbstractforCELSR1 Acts as an Oncogene Regulated by miR-199a-5p in Glioma | Full Text | References | PDF (5.2 MB) | EPUB
  • 76 Views
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Article
Oncological Outcome of Combining Cytoreductive Prostatectomy and Metastasis-Directed Radiotherapy in Patients with Prostate Cancer and Bone Oligometastases: A Retrospective Cohort Study
Peng Xue, Ziyu Wu, Kunpen Wang, Guojun Gao, Min Zhuang & Miao Yan
Pages: 8867-8873
Published online: 23 Sep 2020
AbstractforOncological Outcome of Combining Cytoreductive Prostatectomy and Metastasis-Directed Radiotherapy in Patients with Prostate Cancer and Bone Oligometastases: A Retrospective Cohort Study | Full Text | References | PDF (1.7 MB) | EPUB
  • 89 Views
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Article
The Prognostic Value of Combination of Plasma Fibrinogen and CA19-9 in Non-Distant Metastatic Breast Cancer Patients Undergoing Surgery
Wenjing Hu, Chen Zheng, Ruida Quan, Xuanxuan Dai & Xiaohua Zhang
Pages: 8875-8886
Published online: 23 Sep 2020
AbstractforThe Prognostic Value of Combination of Plasma Fibrinogen and CA19-9 in Non-Distant Metastatic Breast Cancer Patients Undergoing Surgery | Full Text | References | PDF (3 MB) | EPUB
  • 71 Views
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Article
Elevated Expression of CAV1 is Associated with Unfavorable Prognosis of Patients with Breast Cancer Who Undergo Surgery and Neoadjuvant Chemotherapy
Jia-Hui Ye, Jia-Jun Shi, Xi Yin, Hong-Yan Wu, Xin-Yun Xu, Yong-Zhong Yao & Wei-Jie Zhang
Pages: 8887-8892
Published online: 22 Sep 2020
AbstractforElevated Expression of CAV1 is Associated with Unfavorable Prognosis of Patients with Breast Cancer Who Undergo Surgery and Neoadjuvant Chemotherapy | Full Text | References | PDF (966.9 KB) | EPUB
  • 78 Views
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Article
EGLIF-CAR-T Cells Secreting PD-1 Blocking Antibodies Significantly Mediate the Elimination of Gastric Cancer
Jing-Tao Zhou, Jiang-Hao Liu, Ting-Ting Song, Bo Ma, Nuermaimait Amidula & Chao Bai
Pages: 8893-8902
Published online: 23 Sep 2020
AbstractforEGLIF-CAR-T Cells Secreting PD-1 Blocking Antibodies Significantly Mediate the Elimination of Gastric Cancer | Full Text | References | PDF (6.7 MB) | EPUB
  • 146 Views
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Article
Comprehensive Pulmonary Rehabilitation is an Effective Way for Better Postoperative Outcomes in Surgical Lung Cancer Patients with Risk Factors: A Propensity Score-Matched Retrospective Cohort Study
Kun Zhou, Yutian Lai, Yan Wang, Xin Sun, Chunmei Mo, Jiao Wang, Yanming Wu, Jue Li, Shuai Chang & Guowei Che
Pages: 8903-8912
Published online: 23 Sep 2020
AbstractforComprehensive Pulmonary Rehabilitation is an Effective Way for Better Postoperative Outcomes in Surgical Lung Cancer Patients with Risk Factors: A Propensity Score-Matched Retrospective Cohort Study | Full Text | References | PDF (3.8 MB) | EPUB
  • 106 Views
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Article
The Role of Radiotherapy in the Treatment of Retroperitoneal Lymph Node Metastases from Colorectal Cancer
Pei Shu, Ganlu Ouyang, Fang Wang, Jitao Zhou, Yali Shen, Zhiping Li & Xin Wang
Pages: 8913-8921
Published online: 23 Sep 2020
AbstractforThe Role of Radiotherapy in the Treatment of Retroperitoneal Lymph Node Metastases from Colorectal Cancer | Full Text | References | PDF (1.4 MB) | EPUB
  • 152 Views
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Review

Review Article
The Landscape of COVID-19 in Cancer Patients: Prevalence, Impacts, and Recommendations
Omar Abdihamid, Changjing Cai, Linda Kapesa & Shan Zeng
Pages: 8923-8933
Published online: 23 Sep 2020
AbstractforThe Landscape of COVID-19 in Cancer Patients: Prevalence, Impacts, and Recommendations | Full Text | References | PDF (664.5 KB) | EPUB
  • 97 Views
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Original Research

Article
Real-world Data on the Efficacy and Safety of Ixazomib-based Therapy in Multiple Myeloma: A Single-center Study in China
Kai Ding, Hong Yu, Yuan-Yuan Shao, Li-Yan Li, Chao-Meng Wang, Jia Song, Li-Juan Li & Rong Fu
Pages: 8935-8941
Published online: 23 Sep 2020
AbstractforReal-world Data on the Efficacy and Safety of Ixazomib-based Therapy in Multiple Myeloma: A Single-center Study in China | Full Text | References | PDF (270.2 KB) | EPUB
  • 61 Views
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Article
Identification of Apolipoprotein E as a Potential Diagnostic Biomarker of Nasopharyngeal Carcinoma
Ying Xue, Shuo Huang, Jing Huang, Shuang Li, Cen Zhang & Xuhong Zhou
Pages: 8943-8950
Published online: 24 Sep 2020
AbstractforIdentification of Apolipoprotein E as a Potential Diagnostic Biomarker of Nasopharyngeal Carcinoma | Full Text | References | PDF (2.3 MB) | EPUB
  • 65 Views
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Article
CircRNA CDR1as/miR-1287/Raf1 Axis Modulates Hepatocellular Carcinoma Progression Through MEK/ERK Pathway
Bashan Zhang, Fei Li, Zinian Zhu, Aijiao Ding & Jintong Luo
Pages: 8951-8964
Published online: 24 Sep 2020
AbstractforCircRNA CDR1as/miR-1287/Raf1 Axis Modulates Hepatocellular Carcinoma Progression Through MEK/ERK Pathway | Full Text | References | PDF (10 MB) | EPUB
  • 82 Views
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Case Series

Case Report
Analysis of Clinicopathological Features of Cervical Mucinous Adenocarcinoma with a Solitary Ovarian Metastatic Mass as the First Manifestation
Shuanghuan Liu, Yunquan Guo, Bin Li, Huijuan Zhang, Rong Zhang & Shan Zheng
Pages: 8965-8973
Published online: 24 Sep 2020
AbstractforAnalysis of Clinicopathological Features of Cervical Mucinous Adenocarcinoma with a Solitary Ovarian Metastatic Mass as the First Manifestation | Full Text | References | PDF (968.6 KB) | EPUB
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Original Research

Article
RETRACTED ARTICLE: Long Noncoding RNA LINC00839 Promotes the Malignant Progression of Osteosarcoma by Competitively Binding to MicroRNA-454-3p and Consequently Increasing c-Met Expression
Yang Zhang, Hai Guo, Li Ma, Xiaoyong Chen & Guangdong Chen
Pages: 8975-8987
Published online: 24 Sep 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA LINC00839 Promotes the Malignant Progression of Osteosarcoma by Competitively Binding to MicroRNA-454-3p and Consequently Increasing c-Met Expression | PDF (8.8 MB)
  • 27 Views
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Article
MiR-25-3p Serves as an Oncogenic MicroRNA by Downregulating the Expression of Merlin in Osteosarcoma
Hua-chun Rao, Zhao-ke Wu, Si-da Wei, Yun Jiang, Qing-xin Guo, Jia-wen Wang, Chang-xian Chen & Hui-yong Yang
Pages: 8989-9001
Published online: 24 Sep 2020
AbstractforMiR-25-3p Serves as an Oncogenic MicroRNA by Downregulating the Expression of Merlin in Osteosarcoma | Full Text | References | PDF (13.3 MB) | EPUB
  • 94 Views
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Article
Role of Multimodal Treatment in Urothelial Carcinoma Spinal Metastasis: 15 Patients’ Experiences in a Single Center
Tao Wang, Xin Gao, Kun Zhang, Jian Yang, Zheyu Wu, Tielong Liu, Qi Jia & Jianru Xiao
Pages: 9003-9012
Published online: 24 Sep 2020
AbstractforRole of Multimodal Treatment in Urothelial Carcinoma Spinal Metastasis: 15 Patients’ Experiences in a Single Center | Full Text | References | PDF (2 MB) | EPUB
  • 84 Views
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Article
The Clinical Impacts of Pretreatment Peripheral Blood Ratio on Lymphocytes, Monocytes, and Neutrophils Among Patients with Laryngeal/Hypopharyngeal Cancer Treated by Chemoradiation/Radiation
Hui-Ching Chuang, Ming-Hsien Tsai, Yu-Tsai Lin, Ming-Huei Chou, Tai-Lin Huang, Tai-Jan Chiu, Hui Lu, Fu-Min Fang & Chih-Yen Chien
Pages: 9013-9021
Published online: 25 Sep 2020
AbstractforThe Clinical Impacts of Pretreatment Peripheral Blood Ratio on Lymphocytes, Monocytes, and Neutrophils Among Patients with Laryngeal/Hypopharyngeal Cancer Treated by Chemoradiation/Radiation | Full Text | References | PDF (1,004 KB) | EPUB
  • 94 Views
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Article
Preoperative Risk Classification Using Neutrophil-to-Lymphocyte Ratio and Albumin for Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy
Zihan Zhao, Shangxun Xie, Baofu Feng, Shiwei Zhang, Yifan Sun, Hongqian Guo & Rong Yang
Pages: 9023-9032
Published online: 25 Sep 2020
AbstractforPreoperative Risk Classification Using Neutrophil-to-Lymphocyte Ratio and Albumin for Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy | Full Text | References | PDF (3 MB) | EPUB
  • 74 Views
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Article
RETRACTED ARTICLE: Long-Noncoding RNA CASC9 Promotes Progression of Non-Small Cell Lung Cancer by Promoting the Expression of CDC6 Through Binding to HuR
Xudong Zhang, Ting Lian, Wenjun Fan, Guangwei Zhang, Ziwei Chen, Xingchun Gou & Rajiv Kumar Jha
Pages: 9033-9043
Published online: 25 Sep 2020
AbstractforRETRACTED ARTICLE: Long-Noncoding RNA CASC9 Promotes Progression of Non-Small Cell Lung Cancer by Promoting the Expression of CDC6 Through Binding to HuR | PDF (8.1 MB)
  • 66 Views
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Article
Knowledge and Attitude of Ethiopian Oncology Nurses About Cancer Pain Management: National Survey
Biruk Adie Admass, Nigussie Simeneh Endalew, Hailu Yimer Tawuye & Abraham Tarekegn Mersha
Pages: 9045-9055
Published online: 25 Sep 2020
AbstractforKnowledge and Attitude of Ethiopian Oncology Nurses About Cancer Pain Management: National Survey | Full Text | References | PDF (337.1 KB) | EPUB
  • 468 Views
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Article
Fibrinogen/Lymphocyte Count Ratio Can Be Used as a New Indicator of Prognosis in Patients with Hepatocellular Carcinoma After Radical Resection
Yicheng Li, Zhengli Li, Kangjian Deng, Minjun Liao, Shengguang Yuan & Zhaoquan Huang
Pages: 9057-9066
Published online: 01 Oct 2020
AbstractforFibrinogen/Lymphocyte Count Ratio Can Be Used as a New Indicator of Prognosis in Patients with Hepatocellular Carcinoma After Radical Resection | Full Text | References | PDF (4.6 MB) | EPUB
  • 62 Views
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Article
Evaluating the Performance of p16INK4a Immunocytochemistry in Cervical Cancer Screening
Fangbin Song, Hui Du, Aimin Xiao, Chun Wang, Xia Huang, Peisha Yan, Zhihong Liu, Xinfeng Qu, Jerome L Belinson & Ruifang Wu
Pages: 9067-9075
Published online: 25 Sep 2020
AbstractforEvaluating the Performance of p16INK4a Immunocytochemistry in Cervical Cancer Screening | Full Text | References | PDF (1.5 MB) | EPUB
  • 138 Views
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Article
miR-210 is a Serological Biomarker for Predicting Recurrence and Prognosis of Colon Carcinoma Patients with Liver Metastases After Radiofrequency Ablation Treatment
Yong Zhang, Yu-Mei Zhou, Zu-Jian Zhang & Xin Li
Pages: 9077-9085
Published online: 25 Sep 2020
AbstractformiR-210 is a Serological Biomarker for Predicting Recurrence and Prognosis of Colon Carcinoma Patients with Liver Metastases After Radiofrequency Ablation Treatment | Full Text | References | PDF (857.2 KB) | EPUB
  • 63 Views
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Article
RETRACTED ARTICLE: The Hsa_circ_0091579/miR-940/TACR1 Axis Regulates the Development of Hepatocellular Carcinoma
Peiqiang Jiang, Wei Han, Yu Fu & Qingmin Chen
Pages: 9087-9096
Published online: 28 Sep 2020
AbstractforRETRACTED ARTICLE: The Hsa_circ_0091579/miR-940/TACR1 Axis Regulates the Development of Hepatocellular Carcinoma | PDF (5.8 MB)
  • 26 Views
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Article
CREB1 Suppresses Transcription of microRNA-186 to Promote Growth, Invasion and Epithelial–Mesenchymal Transition of Gastric Cancer Cells Through the KRT8/HIF-1α Axis
Xue Huang, Fujian Liu, Zhiyong Jiang, Hang Guan & Qiuhong Jia
Pages: 9097-9111
Published online: 25 Sep 2020
AbstractforCREB1 Suppresses Transcription of microRNA-186 to Promote Growth, Invasion and Epithelial–Mesenchymal Transition of Gastric Cancer Cells Through the KRT8/HIF-1α Axis | Full Text | References | PDF (13 MB) | EPUB
  • 92 Views
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Article
Long Non-Coding RNA SNHG14 Regulates SPIN1 Expression to Accelerate Tumor Progression in Non-Small Cell Lung Cancer by Sponging miR-382-5p
Xiaoliang Chen, Pingan Song, Yuan Yao & Yang Yang
Pages: 9113-9123
Published online: 25 Sep 2020
AbstractforLong Non-Coding RNA SNHG14 Regulates SPIN1 Expression to Accelerate Tumor Progression in Non-Small Cell Lung Cancer by Sponging miR-382-5p | Full Text | References | PDF (7 MB) | EPUB
  • 69 Views
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Article
Knockdown of circPRKCA Restrained Cell Growth, Migration, and Invasion of NSCLC Cells Both in vitro and in vivo via Regulating miR-330-5p/PDK1/AKT Pathway
Lanxiang Bai, Xiaonu Peng & Ruimei Sun
Pages: 9125-9137
Published online: 25 Sep 2020
AbstractforKnockdown of circPRKCA Restrained Cell Growth, Migration, and Invasion of NSCLC Cells Both in vitro and in vivo via Regulating miR-330-5p/PDK1/AKT Pathway | Full Text | References | PDF (6.3 MB) | EPUB
  • 66 Views
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Review

Review Article
Management of Immune Checkpoint Inhibitor Toxicities
Quentin Durrechou, Charlotte Domblides, Baptiste Sionneau, Felix Lefort, Amandine Quivy, Alain Ravaud, Marine Gross-Goupil & Amaury Daste
Pages: 9139-9158
Published online: 28 Sep 2020
AbstractforManagement of Immune Checkpoint Inhibitor Toxicities | Full Text | References | PDF (2.2 MB) | EPUB
  • 177 Views
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Original Research

Article
Downregulation of circNRIP1 Suppresses the Paclitaxel Resistance of Ovarian Cancer via Regulating the miR-211-5p/HOXC8 Axis
Meng Li, Junna Cai, Xiaorui Han & Yue Ren
Pages: 9159-9171
Published online: 28 Sep 2020
AbstractforDownregulation of circNRIP1 Suppresses the Paclitaxel Resistance of Ovarian Cancer via Regulating the miR-211-5p/HOXC8 Axis | Full Text | References | PDF (10.4 MB) | EPUB
  • 75 Views
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Article
A Retrospective Analysis of Dose Distribution and Toxicity in Patients with Left Breast Cancer Treated with Adjuvant Intensity-Modulated Radiotherapy: Comparison with Three-Dimensional Conformal Radiotherapy
Chia-Hsin Chen, Ching-Chuan Hsieh, Chih-Shen Chang & Miao-Fen Chen
Pages: 9173-9182
Published online: 28 Sep 2020
AbstractforA Retrospective Analysis of Dose Distribution and Toxicity in Patients with Left Breast Cancer Treated with Adjuvant Intensity-Modulated Radiotherapy: Comparison with Three-Dimensional Conformal Radiotherapy | Full Text | References | PDF (1.7 MB) | EPUB
  • 129 Views
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Article
Postoperative Adjuvant Transarterial Chemoembolization Improves Short-Term Prognosis of Hepatocellular Carcinoma with Bile Duct Tumor Thrombus: A Propensity-Score Matching Study
Qizhen Huang, Kongying Lin, Lei Wang, Jianxing Zeng, Hongzhi Liu, Zongren Ding, Yongyi Zeng & Jingfeng Liu
Pages: 9183-9195
Published online: 28 Sep 2020
AbstractforPostoperative Adjuvant Transarterial Chemoembolization Improves Short-Term Prognosis of Hepatocellular Carcinoma with Bile Duct Tumor Thrombus: A Propensity-Score Matching Study | Full Text | References | PDF (3.7 MB) | EPUB
  • 73 Views
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Article
microRNA-139-3p Inhibits Malignant Behaviors of Laryngeal Cancer Cells via the KDM5B/SOX2 Axis and the Wnt/β-Catenin Pathway
Yifei Ma, Zili Chen & Guodong Yu
Pages: 9197-9209
Published online: 28 Sep 2020
AbstractformicroRNA-139-3p Inhibits Malignant Behaviors of Laryngeal Cancer Cells via the KDM5B/SOX2 Axis and the Wnt/β-Catenin Pathway | Full Text | References | PDF (10.5 MB) | EPUB
  • 80 Views
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Article
Identifying Risk Factors for Regional Recurrence in Early-Stage Breast Cancer with pT1-2 and Negative Sentinel Lymph Node Biopsy
Kai-yun You, Zhuo-fei Bi, Lin Ding, Yu-jia Ma, Yi-min Liu & He-rui Yao
Pages: 9211-9219
Published online: 28 Sep 2020
AbstractforIdentifying Risk Factors for Regional Recurrence in Early-Stage Breast Cancer with pT1-2 and Negative Sentinel Lymph Node Biopsy | Full Text | References | PDF (2.8 MB) | EPUB
  • 55 Views
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Article
Gambogic Acid Inhibits the Progression of Gastric Cancer via circRNA_ASAP2/miR-33a-5p/CDK7 Axis
Dan Lin, Xiaoyang Lin, Tianlin He & Guoqun Xie
Pages: 9221-9233
Published online: 28 Sep 2020
AbstractforGambogic Acid Inhibits the Progression of Gastric Cancer via circRNA_ASAP2/miR-33a-5p/CDK7 Axis | Full Text | References | PDF (8.2 MB) | EPUB
  • 83 Views
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Article
Exploration of the Potential Biomarkers of Papillary Thyroid Cancer (PTC) Based on RT2 Profiler PCR Arrays and Bioinformatics Analysis
Ying Peng, Han-Wen Zhang, Wei-Han Cao, Ying Mao & Ruo-Chuan Cheng
Pages: 9235-9246
Published online: 28 Sep 2020
AbstractforExploration of the Potential Biomarkers of Papillary Thyroid Cancer (PTC) Based on RT2 Profiler PCR Arrays and Bioinformatics Analysis | Full Text | References | PDF (7 MB) | EPUB
  • 157 Views
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Article
Long Non-Coding RNA H19 Promotes Proliferation, Migration and Invasion and Inhibits Apoptosis of Breast Cancer Cells by Targeting miR-491-5p/ZNF703 Axis
Yongkun Wang, Zhen Wu, Yingxue Li, Zheng Zheng, Jinqiang Yan, Shuyan Tian & Lin Han
Pages: 9247-9258
Published online: 28 Sep 2020
AbstractforLong Non-Coding RNA H19 Promotes Proliferation, Migration and Invasion and Inhibits Apoptosis of Breast Cancer Cells by Targeting miR-491-5p/ZNF703 Axis | Full Text | References | PDF (7.5 MB) | EPUB
  • 101 Views
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Article
Identification of G2 and S Phase-Expressed-1 as a Potential Biomarker in Patients with Prostate Cancer
Jian Xiong, Jianzhong Zhang & Hongjun Li
Pages: 9259-9269
Published online: 28 Sep 2020
AbstractforIdentification of G2 and S Phase-Expressed-1 as a Potential Biomarker in Patients with Prostate Cancer | Full Text | References | PDF (9.7 MB) | EPUB
  • 71 Views
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Article
Circ_0084927 Facilitates Cervical Cancer Development via Sponging miR-142-3p and Upregulating ARL2
Liquan Chen, Xiaowei Zhang, Su Wang, Xiaoting Lin & Lizhen Xu
Pages: 9271-9283
Published online: 28 Sep 2020
AbstractforCirc_0084927 Facilitates Cervical Cancer Development via Sponging miR-142-3p and Upregulating ARL2 | Full Text | References | PDF (7.4 MB) | EPUB
  • 86 Views
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Article
miR-758-3p Inhibits Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Predicts Favorable Prognosis
Yao Wu & Yan Liu
Pages: 9285-9295
Published online: 30 Sep 2020
AbstractformiR-758-3p Inhibits Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Predicts Favorable Prognosis | Full Text | References | PDF (7.2 MB) | EPUB
  • 54 Views
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Article
The Application of Three-Dimensional Visualization in Preoperative Evaluation of Portal Vein Invasion in Hilar Cholangiocarcinoma
Jun Zhang, Xiaochao Guo, He Wang, Jixin Zhang, Ping Liu, Qilu Qiao & Xin Wang
Pages: 9297-9302
Published online: 29 Sep 2020
AbstractforThe Application of Three-Dimensional Visualization in Preoperative Evaluation of Portal Vein Invasion in Hilar Cholangiocarcinoma | Full Text | References | PDF (1.5 MB) | EPUB
  • 55 Views
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Article
Plasma Fibrinogen Predicts the Prognosis of Bladder Cancer Patients After Radical Cystectomy
Shuai Yang, Han Guan, Sheng Wang, Hongliang Wu, Wenyan Sun, Zhijun Chen & Qingwen Li
Pages: 9303-9314
Published online: 29 Sep 2020
AbstractforPlasma Fibrinogen Predicts the Prognosis of Bladder Cancer Patients After Radical Cystectomy | Full Text | References | PDF (5.4 MB) | EPUB
  • 85 Views
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Article
Up-Regulation of circRNA hsa_circ_0003074 Expression is a Reliable Diagnostic and Prognostic Biomarker in Patients with Osteosarcoma
Saiyun Lei & Lei Xiang
Pages: 9315-9325
Published online: 29 Sep 2020
AbstractforUp-Regulation of circRNA hsa_circ_0003074 Expression is a Reliable Diagnostic and Prognostic Biomarker in Patients with Osteosarcoma | Full Text | References | PDF (6 MB) | EPUB
  • 62 Views
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Article
LncRNA GATA6-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer via Repressing microRNA-543 to Up-Regulating RKIP
Zixuan Gong, Xiaoyu Chen, YueChao Zhang, Cheng Liu, Zhibing Wang, Xiaoyan Xu, Jun Zhu & Tongqing Xue
Pages: 9327-9338
Published online: 29 Sep 2020
AbstractforLncRNA GATA6-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer via Repressing microRNA-543 to Up-Regulating RKIP | Full Text | References | PDF (6.7 MB) | EPUB
  • 164 Views
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Article
Long Noncoding RNA EBLN3P Promotes the Progression of Liver Cancer via Alteration of microRNA-144-3p/DOCK4 Signal
Hang Li, Min Wang, Hui Zhou, Shan Lu & Bo Zhang
Pages: 9339-9349
Published online: 29 Sep 2020
AbstractforLong Noncoding RNA EBLN3P Promotes the Progression of Liver Cancer via Alteration of microRNA-144-3p/DOCK4 Signal | Full Text | References | PDF (1.7 MB) | EPUB
  • 106 Views
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Article
CircCFL1/MiR-107 Axis Targeting HMGB1 Promotes the Malignant Progression of Diffuse Large B-Cell Lymphoma Tumors
Xiaowei Chen, Xiaobin Xie & Wei Zhou
Pages: 9351-9362
Published online: 30 Sep 2020
AbstractforCircCFL1/MiR-107 Axis Targeting HMGB1 Promotes the Malignant Progression of Diffuse Large B-Cell Lymphoma Tumors | Full Text | References | PDF (8.8 MB) | EPUB
  • 69 Views
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Review

Review Article
Benefits and Limitations of a Multidisciplinary Approach in Cancer Patient Management
Rossana Berardi, Francesca Morgese, Silvia Rinaldi, Mariangela Torniai, Giulia Mentrasti, Laura Scortichini & Riccardo Giampieri
Pages: 9363-9374
Published online: 30 Sep 2020
AbstractforBenefits and Limitations of a Multidisciplinary Approach in Cancer Patient Management | Full Text | References | PDF (618.9 KB) | EPUB
  • 1554 Views
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Review Article
Progress: Targeted Therapy, Immunotherapy, and New Chemotherapy Strategies in Advanced Triple-Negative Breast Cancer
Jinhong Shi, Feiqi Liu & Yanqiu Song
Pages: 9375-9387
Published online: 30 Sep 2020
AbstractforProgress: Targeted Therapy, Immunotherapy, and New Chemotherapy Strategies in Advanced Triple-Negative Breast Cancer | Full Text | References | PDF (358.3 KB) | EPUB
  • 199 Views
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Review Article
Application and Prospects of Molecular Imaging in Immunotherapy
Weiqing Wang, Zhenhua Gao, Lu Wang, Jianing Li, Jinming Yu, Shumei Han & Xue Meng
Pages: 9389-9403
Published online: 30 Sep 2020
AbstractforApplication and Prospects of Molecular Imaging in Immunotherapy | Full Text | References | PDF (988.5 KB) | EPUB
  • 82 Views
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Original Research

Article
Curcumin Modifies Epithelial–Mesenchymal Transition in Colorectal Cancer Through Regulation of miR-200c/EPM5
Hui Wang, Xiaolong Cai & Longyang Ma
Pages: 9405-9415
Published online: 01 Oct 2020
AbstractforCurcumin Modifies Epithelial–Mesenchymal Transition in Colorectal Cancer Through Regulation of miR-200c/EPM5 | Full Text | References | PDF (4.5 MB) | EPUB
  • 83 Views
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Article
MicroRNA-139 Suppresses the Tumorigenicity of Triple Negative Breast Cancer Cells by Targeting SOX8
Liangliang Dong, Dongmei Zhou, Chunxia Xin, Bing Liu & Ping Sun
Pages: 9417-9428
Published online: 30 Sep 2020
AbstractforMicroRNA-139 Suppresses the Tumorigenicity of Triple Negative Breast Cancer Cells by Targeting SOX8 | Full Text | References | PDF (11.1 MB) | EPUB
  • 78 Views
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Article
Neutrophil-to-Lymphocyte Ratio and Its Changes are Related to Grade II–IV Glioma Recurrence
Lianghua Ma, Guang Li & Minjie Wei
Pages: 9429-9434
Published online: 30 Sep 2020
AbstractforNeutrophil-to-Lymphocyte Ratio and Its Changes are Related to Grade II–IV Glioma Recurrence | Full Text | References | PDF (917.8 KB) | EPUB
  • 62 Views
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Article
Hsa_circ_0084927 Regulates Cervical Cancer Advancement via Regulation of the miR-634/TPD52 Axis
Peijing Shi, Xiaoyong Zhang, Chunxiang Lou, Yunxia Xue, Ruibao Guo & Shuzhen Chen
Pages: 9435-9448
Published online: 02 Oct 2020
AbstractforHsa_circ_0084927 Regulates Cervical Cancer Advancement via Regulation of the miR-634/TPD52 Axis | Full Text | References | PDF (10.9 MB) | EPUB
  • 74 Views
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Case Report

Case Report
Simultaneous Presentation of Leukemic Non-Nodal Mantle Cell Lymphoma and Gamma-Delta T-Large Granular Lymphocytic Leukemia in a Patient with Rheumatoid Arthritis
Vadim R Gorodetskiy, Natalya A Probatova, Natalia A Kupryshina, Svetlana G Palshina, Tatiana N Obukhova, Yulia V Sidorova, Natalya V Ryzhikova & Andrey B Sudarikov
Pages: 9449-9457
Published online: 30 Sep 2020
AbstractforSimultaneous Presentation of Leukemic Non-Nodal Mantle Cell Lymphoma and Gamma-Delta T-Large Granular Lymphocytic Leukemia in a Patient with Rheumatoid Arthritis | Full Text | References | PDF (3.5 MB) | EPUB
  • 104 Views
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Original Research

Article
Circ_0058124 Aggravates the Progression of Papillary Thyroid Carcinoma by Activating LMO4 Expression via Targeting miR-370-3p
Lei Liu, Chaohui Yan, Shudong Tao & Hailing Wang
Pages: 9459-9470
Published online: 01 Oct 2020
AbstractforCirc_0058124 Aggravates the Progression of Papillary Thyroid Carcinoma by Activating LMO4 Expression via Targeting miR-370-3p | Full Text | References | PDF (9.4 MB) | EPUB
  • 68 Views
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Article
Predictive Values of Preoperative Prognostic Nutritional Index and Systemic Immune-Inflammation Index for Long-Term Survival in High-Risk Non-Muscle-Invasive Bladder Cancer Patients: A Single-Centre Retrospective Study
Huifeng Bi, Zhenhua Shang, Chunsong Jia, Jiangtao Wu, Bo Cui, Qi Wang & Tongwen Ou
Pages: 9471-9483
Published online: 01 Oct 2020
AbstractforPredictive Values of Preoperative Prognostic Nutritional Index and Systemic Immune-Inflammation Index for Long-Term Survival in High-Risk Non-Muscle-Invasive Bladder Cancer Patients: A Single-Centre Retrospective Study | Full Text | References | PDF (789.4 KB) | EPUB
  • 102 Views
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Article
Postoperative Short-term Outcomes Between Sublobar Resection and Lobectomy in Patients with Lung Adenocarcinoma
Jiaqi Zhang, Wenliang Bai, Chao Guo, Lei Liu, Guige Wang, Cheng Huang, Yeye Chen, Ye Zhang & Shanqing Li
Pages: 9485-9493
Published online: 01 Oct 2020
AbstractforPostoperative Short-term Outcomes Between Sublobar Resection and Lobectomy in Patients with Lung Adenocarcinoma | Full Text | References | PDF (2.1 MB) | EPUB
  • 60 Views
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Article
Serum lncRNAs (CCAT2, LINC01133, LINC00511) with Squamous Cell Carcinoma Antigen Panel as Novel Non-Invasive Biomarkers for Detection of Cervical Squamous Carcinoma
Wen-Jie Wang, Di Wang, Mei Zhao, Xiao-Jie Sun, Yan Li, Hong Lin, Yi-Qun Che & Chang-Zhi Huang
Pages: 9495-9502
Published online: 01 Oct 2020
AbstractforSerum lncRNAs (CCAT2, LINC01133, LINC00511) with Squamous Cell Carcinoma Antigen Panel as Novel Non-Invasive Biomarkers for Detection of Cervical Squamous Carcinoma | Full Text | References | PDF (2.7 MB) | EPUB
  • 73 Views
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Article
Oxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis
Xiaoping Li, Jie Sun, Qinghua Xu, Weiping Duan, Licheng Yang, Xing Wu, Guang Lu, Li Zhang & Yunfeng Zheng
Pages: 9503-9513
Published online: 01 Oct 2020
AbstractforOxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis | Full Text | References | PDF (7.8 MB) | EPUB
  • 96 Views
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Article
Long Non-Coding RNA SNHG14 Impedes Viability, Migration and Invasion of Endometrial Carcinoma Cells Through Modulating miR-93-5p/ZBTB7A Axis
Kai Zhang, Yongqin Cai, Qi Zhou, Hong Sun & Jinying Wei
Pages: 9515-9525
Published online: 01 Oct 2020
AbstractforLong Non-Coding RNA SNHG14 Impedes Viability, Migration and Invasion of Endometrial Carcinoma Cells Through Modulating miR-93-5p/ZBTB7A Axis | Full Text | References | PDF (7.5 MB) | EPUB
  • 73 Views
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Article
Epidemiology of Gallbladder Cancer in Saudi Arabia
Saleh A Alqahtani & Ibrahim G Alghamdi
Pages: 9527-9537
Published online: 02 Oct 2020
AbstractforEpidemiology of Gallbladder Cancer in Saudi Arabia | Full Text | References | PDF (9.2 MB) | EPUB
  • 78 Views
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Article
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway
Rui Zhang, Dan Han, Lu Li, Wenguang Luo, Jing Liu & Liting Qian
Pages: 9539-9549
Published online: 02 Oct 2020
AbstractforEphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway | Full Text | References | PDF (5.3 MB) | EPUB
  • 69 Views
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Review

Review Article
Managing Ipilimumab-Induced Hypophysitis: Challenges and Current Therapeutic Strategies
Marina Tsoli, Gregory Kaltsas, Anna Angelousi, Krystallenia Alexandraki, Harpal Randeva & Eva Kassi
Pages: 9551-9561
Published online: 02 Oct 2020
AbstractforManaging Ipilimumab-Induced Hypophysitis: Challenges and Current Therapeutic Strategies | Full Text | References | PDF (1.9 MB) | EPUB
  • 105 Views
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Original Research

Article
CircCSNK1G1 Contributes to the Development of Colorectal Cancer by Increasing the Expression of MYO6 via Competitively Targeting miR-455-3p
Xianming Huang, Xiaohua Shen, Lixiang Peng, Wenli Mai, Yiye Wan & Huiqing Zhang
Pages: 9563-9575
Published online: 02 Oct 2020
AbstractforCircCSNK1G1 Contributes to the Development of Colorectal Cancer by Increasing the Expression of MYO6 via Competitively Targeting miR-455-3p | Full Text | References | PDF (9.2 MB) | EPUB
  • 64 Views
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Article
CircNFIX Acts as a miR-212-3p Sponge to Enhance the Malignant Progression of Non-Small Cell Lung Cancer by Up-Regulating ADAM10
Jun Lu, Ying Zhu, Youfa Qin & Yikai Chen
Pages: 9577-9587
Published online: 02 Oct 2020
AbstractforCircNFIX Acts as a miR-212-3p Sponge to Enhance the Malignant Progression of Non-Small Cell Lung Cancer by Up-Regulating ADAM10 | Full Text | References | PDF (5 MB) | EPUB
  • 62 Views
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Article
TCEAL2 as a Tumor Suppressor in Renal Cell Carcinoma is Associated with the Good Prognosis of Patients
Yingchen Zhou, Yang Zhang, Weiqing Li, Jinming Xu, Xia He, Xianxin Li & Yan Wang
Pages: 9589-9597
Published online: 02 Oct 2020
AbstractforTCEAL2 as a Tumor Suppressor in Renal Cell Carcinoma is Associated with the Good Prognosis of Patients | Full Text | References | PDF (4.1 MB) | EPUB
  • 70 Views
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Article
Expression of Integrin β6 and HAX-1 Correlates with Aggressive Features and Poor Prognosis in Esophageal Squamous Cell Carcinoma
Fanni Li, Yukui Shang, Feiyu Shi, Lei Zhang, Jun Yan, Qi Sun & Junjun She
Pages: 9599-9608
Published online: 02 Oct 2020
AbstractforExpression of Integrin β6 and HAX-1 Correlates with Aggressive Features and Poor Prognosis in Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (2.3 MB) | EPUB
  • 71 Views
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Article
MCM10 Acts as a Potential Prognostic Biomarker and Promotes Cell Proliferation in Hepatocellular Carcinoma: Integrated Bioinformatics Analysis and Experimental Validation
Wei Wan, Yu Shen & Quanxi Li
Pages: 9609-9619
Published online: 05 Oct 2020
AbstractforMCM10 Acts as a Potential Prognostic Biomarker and Promotes Cell Proliferation in Hepatocellular Carcinoma: Integrated Bioinformatics Analysis and Experimental Validation | Full Text | References | PDF (7 MB) | EPUB
  • 90 Views
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Article
Expression of Zinc Finger and BTB Domain-Containing 4 in Colorectal Cancer and Its Clinical Significance
Tao Xiang, Kangxin He, Saisai Wang, Wenbin Chen & Hui Li
Pages: 9621-9626
Published online: 05 Oct 2020
AbstractforExpression of Zinc Finger and BTB Domain-Containing 4 in Colorectal Cancer and Its Clinical Significance | Full Text | References | PDF (1.4 MB) | EPUB
  • 72 Views
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Case Report

Case Report
Splenic Diffuse Red Pulp Small B-Cell Lymphoma with Gastrointestinal Hemorrhage: A Case Report and Literature Review
Yanqiu Xu, Xiaohui Fan, Cai Sun, Lingling Yin, Tingting Qiu, Jieyun Xia, Xiaomin Zhong, Linyan Xu, Depeng Li, Zhenyu Li, Feng Zhu & Kailin Xu
Pages: 9627-9633
Published online: 06 Oct 2020
AbstractforSplenic Diffuse Red Pulp Small B-Cell Lymphoma with Gastrointestinal Hemorrhage: A Case Report and Literature Review | Full Text | References | PDF (5.8 MB) | EPUB
  • 77 Views
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Original Research

Article
Clinical Characteristics and Prognosis of Rare Histological Variants of Bladder Cancer: A Single-Center Retrospective Study from China
Dengxiong Li, Ao Li, Yubo Yang, Dechao Feng, Facai Zhang, Xiaoming Wang, Yunjin Bai, Yin Tang & Ping Han
Pages: 9635-9641
Published online: 07 Oct 2020
AbstractforClinical Characteristics and Prognosis of Rare Histological Variants of Bladder Cancer: A Single-Center Retrospective Study from China | Full Text | References | PDF (1.1 MB) | EPUB
  • 79 Views
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Article
Sparing Organs at Risk with Simultaneous Integrated Boost Volumetric Modulated Arc Therapy for Locally Advanced Non-Small Cell Lung Cancer: An Automatic Treatment Planning Study
Daquan Wang, Jiayun Chen, Xiaodong Zhang, Tao Zhang, Luhua Wang, Qinfu Feng, Zongmei Zhou, Jianrong Dai & Nan Bi
Pages: 9643-9653
Published online: 06 Oct 2020
AbstractforSparing Organs at Risk with Simultaneous Integrated Boost Volumetric Modulated Arc Therapy for Locally Advanced Non-Small Cell Lung Cancer: An Automatic Treatment Planning Study | Full Text | References | PDF (2.5 MB) | EPUB
  • 88 Views
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Review

Review Article
The Pathogenesis and Prevention of Port-Site Metastasis in Gynecologic Oncology
Qianqian Gao, Ling Guo & Bo Wang
Pages: 9655-9663
Published online: 06 Oct 2020
AbstractforThe Pathogenesis and Prevention of Port-Site Metastasis in Gynecologic Oncology | Full Text | References | PDF (301.1 KB) | EPUB
  • 108 Views
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Original Research

Article
ARHGAP6 Promotes Apoptosis and Inhibits Glycolysis in Lung Adenocarcinoma Through STAT3 Signaling Pathway
Pengfei Li, Huina Lv, Min Xu, Bin Zang & Yegang Ma
Pages: 9665-9678
Published online: 06 Oct 2020
AbstractforARHGAP6 Promotes Apoptosis and Inhibits Glycolysis in Lung Adenocarcinoma Through STAT3 Signaling Pathway | Full Text | References | PDF (8.7 MB) | EPUB
  • 83 Views
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Article
Modulation of Calcium Homeostasis May Be Associated with Susceptibility to Renal Cell Carcinoma in Diabetic Nephropathy Rats
Yueming Luo, Zhaoyu Lu, Ana Maria Waaga-Gasser, Haifeng Yang, Jialing Liu, Juan Wu, Jiayan Lu, Xusheng Liu & Lei Zhang
Pages: 9679-9689
Published online: 07 Oct 2020
AbstractforModulation of Calcium Homeostasis May Be Associated with Susceptibility to Renal Cell Carcinoma in Diabetic Nephropathy Rats | Full Text | References | PDF (4.5 MB) | EPUB
  • 71 Views
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Article
Programmed Death-1 Receptor (PD-1) as a Potential Prognosis Biomarker for Ovarian Cancer Patients
Anna Pawłowska, Dorota Suszczyk, Rafał Tarkowski, Roman Paduch, Jan Kotarski & Iwona Wertel
Pages: 9691-9709
Published online: 07 Oct 2020
AbstractforProgrammed Death-1 Receptor (PD-1) as a Potential Prognosis Biomarker for Ovarian Cancer Patients | Full Text | References | PDF (7.2 MB) | EPUB
  • 81 Views
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Open Access

Retraction

Retraction
Long Non-Coding RNA AGAP2-AS1/miR-628-5p/PTN Axis Modulates Proliferation, Migration, Invasion, and Apoptosis of Glioma Cells [Retraction]
Page: 9711
Published online: 07 Oct 2020
CitationforLong Non-Coding RNA AGAP2-AS1/miR-628-5p/PTN Axis Modulates Proliferation, Migration, Invasion, and Apoptosis of Glioma Cells [Retraction] | Full Text | PDF (164.3 KB) | EPUB
  • 51 Views
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Original Research

Article
Survival and Clinical Outcomes with Telotristat Ethyl in Patients with Carcinoid Syndrome
David C Metz, Eric Liu, Vijay N Joish, Lynn Huynh, Todor I Totev, Mei Sheng Duh, Kiernan Seth, Susan Giacalone, Pablo Lapuerta & Michael A Morse
Pages: 9713-9719
Published online: 07 Oct 2020
AbstractforSurvival and Clinical Outcomes with Telotristat Ethyl in Patients with Carcinoid Syndrome | Full Text | References | PDF (1.4 MB) | EPUB
  • 82 Views
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Open Access

Corrigendum

Correction
Circular RNA Profiling Reveals That circRNA_104433 Regulates Cell Growth by Targeting miR-497-5p in Gastric Cancer [Corrigendum]
Pages: 9721-9724
Published online: 08 Oct 2020
First Page PreviewforCircular RNA Profiling Reveals That circRNA_104433 Regulates Cell Growth by Targeting miR-497-5p in Gastric Cancer [Corrigendum] | Full Text | PDF (3.2 MB) | EPUB
  • 47 Views
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Original Research

Article
ANLN Directly Interacts with RhoA to Promote Doxorubicin Resistance in Breast Cancer Cells
Feng Wang, Zhen Xiang, Teng Huang, Min Zhang & Wei-Bing Zhou
Pages: 9725-9734
Published online: 07 Oct 2020
AbstractforANLN Directly Interacts with RhoA to Promote Doxorubicin Resistance in Breast Cancer Cells | Full Text | References | PDF (4.7 MB) | EPUB
  • 105 Views
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Review

Review Article
Tobacco Smoke Plays an Important Role in Initiation and Development of Lung Cancer by Promoting the Characteristics of Cancer Stem Cells
Ling Lu, Qiaoyan Liang, Shiyue Shen, Lei Feng, Longtao Jin & Zhao feng Liang
Pages: 9735-9739
Published online: 07 Oct 2020
AbstractforTobacco Smoke Plays an Important Role in Initiation and Development of Lung Cancer by Promoting the Characteristics of Cancer Stem Cells | Full Text | References | PDF (679.4 KB) | EPUB
  • 198 Views
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Original Research

Article
Long Noncoding RNA FBXL19-AS1 Expedites Cell Growth, Migration and Invasion in Cervical Cancer by miR-193a-5p/PIN1 Signaling
Su Wan, Guantai Ni, Jin Ding & Yuansheng Huang
Pages: 9741-9752
Published online: 07 Oct 2020
AbstractforLong Noncoding RNA FBXL19-AS1 Expedites Cell Growth, Migration and Invasion in Cervical Cancer by miR-193a-5p/PIN1 Signaling | Full Text | References | PDF (12.1 MB) | EPUB
  • 76 Views
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Article
Evaluation of Serum Exosomal lncRNAs as Diagnostic and Prognostic Biomarkers for Esophageal Squamous Cell Carcinoma
Suzhen Yan, Lutao Du, Xiumei Jiang, Weili Duan, Juan Li, Yujiao Xie, Yao Zhan, Shujun Zhang, Lili Wang, Shuhai Li & Chuanxin Wang
Pages: 9753-9763
Published online: 07 Oct 2020
AbstractforEvaluation of Serum Exosomal lncRNAs as Diagnostic and Prognostic Biomarkers for Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (3.2 MB) | EPUB
  • 93 Views
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Article
Platelet Count is Associated with the Rate of Lymph Node Metastasis in Lung Adenocarcinoma
Cheng-hao Qu, Tong Li, Zhan-peng Tang, Xi-Rui Zhu, Jing-yi Han & Hui Tian
Pages: 9765-9774
Published online: 07 Oct 2020
AbstractforPlatelet Count is Associated with the Rate of Lymph Node Metastasis in Lung Adenocarcinoma | Full Text | References | PDF (352.1 KB) | EPUB
  • 69 Views
  • 5 CrossRef citations
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Article
Hematological Indices of Distant Metastases and Prognostic Nomogram in Gastro-Pancreatic and Biliary Tract Cancers
Razan Mansour, Osama Abu-Shawer, Ali Lattouf, Hala Sultan & Maysa Al-Hussaini
Pages: 9775-9786
Published online: 08 Oct 2020
AbstractforHematological Indices of Distant Metastases and Prognostic Nomogram in Gastro-Pancreatic and Biliary Tract Cancers | Full Text | References | PDF (3.2 MB) | EPUB
  • 72 Views
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Article
Identification and Validation of Novel Genes in Anaplastic Thyroid Carcinoma via Bioinformatics Analysis
Shengnan Wang, Jing Wu, Congcong Guo, Hongxia Shang, Jinming Yao, Lin Liao & Jianjun Dong
Pages: 9787-9799
Published online: 08 Oct 2020
AbstractforIdentification and Validation of Novel Genes in Anaplastic Thyroid Carcinoma via Bioinformatics Analysis | Full Text | References | PDF (7.6 MB) | EPUB
  • 116 Views
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Article
Vessel Size Imaging is Associated with IDH Mutation and Patient Survival in Diffuse Lower-Grade Glioma
Houyi Kang, Peng Chen, Hong Guo, Letian Zhang, Yong Tan, Hualiang Xiao, Ao Yang, Jingqin Fang & Weiguo Zhang
Pages: 9801-9811
Published online: 08 Oct 2020
AbstractforVessel Size Imaging is Associated with IDH Mutation and Patient Survival in Diffuse Lower-Grade Glioma | Full Text | References | PDF (4.2 MB) | EPUB
  • 63 Views
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Article
JAK-STAT Domain Enhanced MUC1-CAR-T Cells Induced Esophageal Cancer Elimination
Heng Zhang, Hui Zhao, Xiaolei He, Feng Xi & Jiwen Liu
Pages: 9813-9824
Published online: 08 Oct 2020
AbstractforJAK-STAT Domain Enhanced MUC1-CAR-T Cells Induced Esophageal Cancer Elimination | Full Text | References | PDF (8 MB) | EPUB
  • 137 Views
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Article
The Significance of Preoperative Serum Sodium and Hemoglobin in Outcomes of Upper Tract Urothelial Carcinoma: Multi-Center Analysis Between China and the United States
Dong Fang, Nirmish Singla, Zhengqing Bao, Syed M Jafri, Xiaohong Su, Zhenpeng Cao, Gengyan Xiong, Lei Zhang, Solomon Woldu, Ryan Hutchinson, Arthur Sagalowsky, Yair Lotan, Xuesong Li, Jay D Raman, Vitaly Margulis & Liqun Zhou
Pages: 9825-9836
Published online: 08 Oct 2020
AbstractforThe Significance of Preoperative Serum Sodium and Hemoglobin in Outcomes of Upper Tract Urothelial Carcinoma: Multi-Center Analysis Between China and the United States | Full Text | References | PDF (3.3 MB) | EPUB
  • 74 Views
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Article
Endobronchial Ultrasound Combined with Clinical Data for Predicting Malignant Peripheral Pulmonary Lesions
Hong-Yan Ren, Xiao-Ju Zhang, Kun Zhang, Tian-Xiao Li, Bu-Lang Gao & Zheng-Xian Chen
Pages: 9837-9844
Published online: 08 Oct 2020
AbstractforEndobronchial Ultrasound Combined with Clinical Data for Predicting Malignant Peripheral Pulmonary Lesions | Full Text | References | PDF (2.1 MB) | EPUB
  • 61 Views
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Article
miR-144-3p Contributes to the Development of Thyroid Tumors Through the PTEN/PI3K/AKT Pathway
Hui-Ling Cao, Ming-Qiang Gu, Zhuo Sun & Zhong-Jian Chen
Pages: 9845-9855
Published online: 09 Oct 2020
AbstractformiR-144-3p Contributes to the Development of Thyroid Tumors Through the PTEN/PI3K/AKT Pathway | Full Text | References | PDF (4.6 MB) | EPUB
  • 65 Views
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Article
FoxM1 is Upregulated in Osteosarcoma and Inhibition of FoxM1 Decreases Osteosarcoma Cell Proliferation, Migration, and Invasion
Xia Zhu, Kangyang Lu, Liyu Cao, Yong Hu, Yu Yin & Yongping Cai
Pages: 9857-9867
Published online: 09 Oct 2020
AbstractforFoxM1 is Upregulated in Osteosarcoma and Inhibition of FoxM1 Decreases Osteosarcoma Cell Proliferation, Migration, and Invasion | Full Text | References | PDF (7.1 MB) | EPUB
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Review

Review Article
Colorectal Cancer Genetics, Incidence and Risk Factors: In Search for Targeted Therapies
Rodney Hull, Flavia Zita Francies, Meryl Oyomno & Zodwa Dlamini
Pages: 9869-9882
Published online: 09 Oct 2020
AbstractforColorectal Cancer Genetics, Incidence and Risk Factors: In Search for Targeted Therapies | Full Text | References | PDF (2.4 MB) | EPUB
  • 496 Views
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Original Research

Article
Prognostic Significance of Pregnancy Zone Protein and Its Correlation with Immune Infiltrates in Hepatocellular Carcinoma
Lisa Su, Genhao Zhang & Xiangdong Kong
Pages: 9883-9891
Published online: 09 Oct 2020
AbstractforPrognostic Significance of Pregnancy Zone Protein and Its Correlation with Immune Infiltrates in Hepatocellular Carcinoma | Full Text | References | PDF (5.2 MB) | EPUB
  • 93 Views
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Article
A Single-Center, 10-Year Retrospective Study on Surgical Treatment and Prognosis Analysis of Differentiated Thyroid Carcinoma with Spinal Metastasis
Shuzhong Liu, Xi Zhou, An Song, Siyuan Yao, Muchuan Wang, Tong Niu, Chengao Gao, Zhen Huo, Yong Liu & Yipeng Wang
Pages: 9893-9904
Published online: 09 Oct 2020
AbstractforA Single-Center, 10-Year Retrospective Study on Surgical Treatment and Prognosis Analysis of Differentiated Thyroid Carcinoma with Spinal Metastasis | Full Text | References | PDF (2.5 MB) | EPUB
  • 92 Views
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Article
DUS4L Silencing Suppresses Cell Proliferation and Promotes Apoptosis in Human Lung Adenocarcinoma Cell Line A549
Zheng Li, Ci Yin, Bin Li, Qi-Yao Yu, Wen-Jie Mao, Jie Li, Jun-Ping Lin, Yu-Qi Meng, Hai-Ming Feng & Tao Jing
Pages: 9905-9913
Published online: 09 Oct 2020
AbstractforDUS4L Silencing Suppresses Cell Proliferation and Promotes Apoptosis in Human Lung Adenocarcinoma Cell Line A549 | Full Text | References | PDF (5.4 MB) | EPUB
  • 74 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA VPS9D1-AS1 Sequesters microRNA-525-5p to Promote the Oncogenicity of Colorectal Cancer Cells by Upregulating HMGA1
Hairui Liu, Xueying Zhang, Xianmei Jin, Yubo Yang, Guodong Liang, Yuehan Ma & Bing Wang
Pages: 9915-9928
Published online: 09 Oct 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA VPS9D1-AS1 Sequesters microRNA-525-5p to Promote the Oncogenicity of Colorectal Cancer Cells by Upregulating HMGA1 | PDF (11.4 MB)
  • 36 Views
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Article
Preoperative Inversed Albumin-to-Globulin Ratio Predicts Worse Oncologic Prognosis Following Curative Hepatectomy for Hepatocellular Carcinoma
Cheng-Cheng Zhang, Cheng-Wu Zhang, Hao Xing, Yu Wang, Lei Liang, Yong-Kang Diao, Ting-Hao Chen, Wan Yee Lau, Ping Bie, Zhi-Yu Chen & Tian Yang
Pages: 9929-9939
Published online: 12 Oct 2020
AbstractforPreoperative Inversed Albumin-to-Globulin Ratio Predicts Worse Oncologic Prognosis Following Curative Hepatectomy for Hepatocellular Carcinoma | Full Text | References | PDF (842.2 KB) | EPUB
  • 89 Views
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Article
Abnormal MGMT Promoter Methylation in Gastrointestinal Stromal Tumors: Genetic Susceptibility and Association with Clinical Outcome
Liping Lou, Wendi Zhang, Jun Li & Yu Wang
Pages: 9941-9952
Published online: 12 Oct 2020
AbstractforAbnormal MGMT Promoter Methylation in Gastrointestinal Stromal Tumors: Genetic Susceptibility and Association with Clinical Outcome | Full Text | References | PDF (1.8 MB) | EPUB
  • 63 Views
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Review

Review Article
Breast Cancer Brain Metastasis: The Potential Role of MRI Beyond Current Clinical Applications
Andria Hadjipanteli, Paul Doolan, Efthyvoulos Kyriacou & Anastasia Constantinidou
Pages: 9953-9964
Published online: 12 Oct 2020
AbstractforBreast Cancer Brain Metastasis: The Potential Role of MRI Beyond Current Clinical Applications | Full Text | References | PDF (1,011.7 KB) | EPUB
  • 146 Views
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Original Research

Article
Circ_0032821 Facilitates Gastric Cancer Cell Proliferation, Migration, Invasion and Glycolysis by Regulating MiR-1236-3p/HMGB1 Axis
Lei Chen, Kun Chi, Huaguo Xiang & Yan Yang
Pages: 9965-9976
Published online: 12 Oct 2020
AbstractforCirc_0032821 Facilitates Gastric Cancer Cell Proliferation, Migration, Invasion and Glycolysis by Regulating MiR-1236-3p/HMGB1 Axis | Full Text | References | PDF (7.6 MB) | EPUB
  • 70 Views
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Article
Mean Platelet Volume Has Prognostic Value in Chronic Lymphocytic Leukemia
Marta Masternak, Bartosz Puła, Joanna Knap, Anna Waszczuk-Gajda, Joanna Drozd-Sokołowska, Kamil Wdowiak, Sebastian Grosicki, Izabela Kozłowska, Marta Kaźmierczak, Anna Łabędź, Łukasz Szukalski, Kamil Wiśniewski, Edyta Subocz, Janusz Hałka, Agnieszka Szymczyk, Marek Hus, Krzysztof Jamroziak & Krzysztof Giannopoulos
Pages: 9977-9985
Published online: 12 Oct 2020
AbstractforMean Platelet Volume Has Prognostic Value in Chronic Lymphocytic Leukemia | Full Text | References | PDF (1.2 MB) | EPUB
  • 193 Views
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Article
MiRNA-128 and MiRNA-142 Regulate Tumorigenesis and EMT in Oral Squamous Cell Carcinoma Through HOXA10
Yao Yao, Qian Xu, Liyong Yan, Yan Jiao, Qingqi Su, Xiaoguang Li, Cong Liu & Feng Zhao
Pages: 9987-9997
Published online: 12 Oct 2020
AbstractforMiRNA-128 and MiRNA-142 Regulate Tumorigenesis and EMT in Oral Squamous Cell Carcinoma Through HOXA10 | Full Text | References | PDF (8.1 MB) | EPUB
  • 84 Views
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Article
RETRACTED ARTICLE: LncRNA MALAT1 Regulates the Progression and Cisplatin Resistance of Ovarian Cancer Cells via Modulating miR-1271-5p/E2F5 Axis
Yuqin Wang, Xiuying Wang, Liwei Han & Dongdong Hu
Pages: 9999-10010
Published online: 12 Oct 2020
AbstractforRETRACTED ARTICLE: LncRNA MALAT1 Regulates the Progression and Cisplatin Resistance of Ovarian Cancer Cells via Modulating miR-1271-5p/E2F5 Axis | PDF (13 MB)
  • 17 Views
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Article
Most Adult Intussusceptions are Caused by Tumors: A Single-Centre Analysis
Tongrong Su, Liang He, Tianyu Zhou, Menghui Wu, Yaohua Guo, Quan Wang, Jing Jiang & Xueyuan Cao
Pages: 10011-10015
Published online: 12 Oct 2020
AbstractforMost Adult Intussusceptions are Caused by Tumors: A Single-Centre Analysis | Full Text | References | PDF (247.3 KB) | EPUB
  • 102 Views
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Article
Standard Treatment Remains the Recommended Approach for Patients with Bone Sarcoma Who Underwent Unplanned Surgery: Report from the Japanese Musculoskeletal Oncology Group
Tomoki Nakamura, Jun Sugaya, Norifumi Naka, Hiroshi Kobayashi, Tomotake Okuma, Toshiyuki Kunisada, Kunihiro Asanuma, Hedetatsu Outani, Shunji Nishimura, Hiroyuki Kawashima, Toru Akiyama, Taketoshi Yasuda, Shinji Miwa, Akihiro Sudo & Takafumi Ueda
Pages: 10017-10022
Published online: 12 Oct 2020
AbstractforStandard Treatment Remains the Recommended Approach for Patients with Bone Sarcoma Who Underwent Unplanned Surgery: Report from the Japanese Musculoskeletal Oncology Group | Full Text | References | PDF (884.1 KB) | EPUB
  • 100 Views
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Article
Combination of Hematology Indicators and Oncological Characteristics as a New Promising Prognostic Factor in Localized Clear Cell Renal Cell Carcinoma
Xiangpeng Kang, Hongzhe Shi, Dong Wang, Zejun Xiao, Jun Tian, Xingang Bi, Weixing Jiang, Changling Li, Jianhui Ma, Shan Zheng, Yueping Sun & Jianzhong Shou
Pages: 10023-10033
Published online: 12 Oct 2020
AbstractforCombination of Hematology Indicators and Oncological Characteristics as a New Promising Prognostic Factor in Localized Clear Cell Renal Cell Carcinoma | Full Text | References | PDF (779.1 KB) | EPUB
  • 74 Views
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Article
RETRACTED ARTICLE: DICER1-AS1 Promotes the Malignant Behaviors of Colorectal Cancer Cells by Regulating miR-296-5p/STAT3 Axis
Chuanyu Ma, Ning Ma, Lili Qin, Chuanna Miao, Minglei Luo & Shuhong Liu
Pages: 10035-10046
Published online: 13 Oct 2020
AbstractforRETRACTED ARTICLE: DICER1-AS1 Promotes the Malignant Behaviors of Colorectal Cancer Cells by Regulating miR-296-5p/STAT3 Axis | PDF (6.1 MB)
  • 39 Views
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Article
Quality of Life and Associated Factors Among Family Caregivers of Adult Cancer Patients in Addis Ababa, Ethiopia
Eyerusalem Yihedego, Fekadu Aga, Debela Gela & Abdisa Boka
Pages: 10047-10054
Published online: 13 Oct 2020
AbstractforQuality of Life and Associated Factors Among Family Caregivers of Adult Cancer Patients in Addis Ababa, Ethiopia | Full Text | References | PDF (313.1 KB) | EPUB
  • 189 Views
  • 6 CrossRef citations
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Article
Knockdown of circ-TTBK2 Inhibits Glioma Progression by Regulating miR-1283 and CHD1
Chengchen Han, Shuwei Wang, Hongwei Wang & Jianning Zhang
Pages: 10055-10065
Published online: 13 Oct 2020
AbstractforKnockdown of circ-TTBK2 Inhibits Glioma Progression by Regulating miR-1283 and CHD1 | Full Text | References | PDF (7.7 MB) | EPUB
  • 51 Views
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Article
Construction and Characterization of KRAS Immune Lipid Magnetic Balls for Colorectal Cancer Circulating Tumor Cells
Chengbao Feng, Jingjing Wang, Xue Yang, Xuefang Zang, Haikun Zhou, Erying Zhang, Haifei Li, Bo Liu, Shumin Chen, Ying Wang, Peng Wang, Lixue Gao & Jinyan Liu
Pages: 10067-10075
Published online: 13 Oct 2020
AbstractforConstruction and Characterization of KRAS Immune Lipid Magnetic Balls for Colorectal Cancer Circulating Tumor Cells | Full Text | References | PDF (4.7 MB) | EPUB
  • 86 Views
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Article
PVT1 Mediates Cell Proliferation, Apoptosis and Radioresistance in Nasopharyngeal Carcinoma Through Regulating miR-515-5p/PIK3CA Axis
Yanyan Han, Fang Li, Jun Xie, Yi Wang & Hua Zhang
Pages: 10077-10090
Published online: 13 Oct 2020
AbstractforPVT1 Mediates Cell Proliferation, Apoptosis and Radioresistance in Nasopharyngeal Carcinoma Through Regulating miR-515-5p/PIK3CA Axis | Full Text | References | PDF (9.9 MB) | EPUB
  • 76 Views
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Article
Prognosis of Adjuvant SOX vs XELOX Chemotherapy for Gastric Cancer After D2 Gastrectomy in Chinese Patients
Shan Yu, Yan Wang, Xi Cheng, Minzhi Lv, Yuehong Cui, Wei Li, Yiyi Yu, Qian Li & Tianshu Liu
Pages: 10091-10101
Published online: 13 Oct 2020
AbstractforPrognosis of Adjuvant SOX vs XELOX Chemotherapy for Gastric Cancer After D2 Gastrectomy in Chinese Patients | Full Text | References | PDF (6.2 MB) | EPUB
  • 97 Views
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Article
Knowledge of Cervical Cancer and Associated Factors Among Women Attending Public Health Facilities in Eastern Ethiopia
Elias Bekele Wakwoya, Kasiye Shiferaw Gemechu & Tamirat Tesfaye Dasa
Pages: 10103-10111
Published online: 14 Oct 2020
AbstractforKnowledge of Cervical Cancer and Associated Factors Among Women Attending Public Health Facilities in Eastern Ethiopia | Full Text | References | PDF (532.7 KB) | EPUB
  • 252 Views
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Article
CBX3 Promotes Gastric Cancer Progression and Affects Factors Related to Immunotherapeutic Responses
Hexin Lin, Jiabian Lian, Lu Xia, Guoxian Guan & Jun You
Pages: 10113-10125
Published online: 14 Oct 2020
AbstractforCBX3 Promotes Gastric Cancer Progression and Affects Factors Related to Immunotherapeutic Responses | Full Text | References | PDF (9 MB) | EPUB
  • 118 Views
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Article
Pretreatment Apparent Diffusion Coefficient as a Predictor of Response to Transcatheter Arterial Chemoembolization Immediately Combined with Radiofrequency Ablation for Treatment of Solitary Large Hepatocellular Carcinoma
Jing Tang, Fengyong Liu, Hongjun Yuan, Xin Li, Xiaomei Tian, Kan Ji, Xueping Li & Wei Wang
Pages: 10127-10138
Published online: 14 Oct 2020
AbstractforPretreatment Apparent Diffusion Coefficient as a Predictor of Response to Transcatheter Arterial Chemoembolization Immediately Combined with Radiofrequency Ablation for Treatment of Solitary Large Hepatocellular Carcinoma | Full Text | References | PDF (1.7 MB) | EPUB
  • 83 Views
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Article
Overexpression of Rab40b Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway
Li-Wei Shi, Zhi-Bo Zhao, Li Zhong, Jian Gao, Jian-Ping Gong, Hang Chen, Yu Min, Yi-Yin Zhang & Zhi Li
Pages: 10139-10150
Published online: 14 Oct 2020
AbstractforOverexpression of Rab40b Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway | Full Text | References | PDF (6.6 MB) | EPUB
  • 60 Views
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Article
Hypoxic Non-Small-Cell Lung Cancer Cell-Secreted Exosomal microRNA-582-3p Drives Cancer Cell Malignant Phenotypes by Targeting Secreted Frizzled-Related Protein 1
Jian Wang, Jia Zhao, Jinsong Zhu & Shengli Zhang
Pages: 10151-10161
Published online: 14 Oct 2020
AbstractforHypoxic Non-Small-Cell Lung Cancer Cell-Secreted Exosomal microRNA-582-3p Drives Cancer Cell Malignant Phenotypes by Targeting Secreted Frizzled-Related Protein 1 | Full Text | References | PDF (5.9 MB) | EPUB
  • 77 Views
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Article
LncRNA-SNHG7 Enhances Chemotherapy Resistance and Cell Viability of Breast Cancer Cells by Regulating miR-186
Hui Zhang, Xiao-Yu Zhang, Xiao-Ning Kang, Li-Jun Jin & Zun-Yi Wang
Pages: 10163-10172
Published online: 14 Oct 2020
AbstractforLncRNA-SNHG7 Enhances Chemotherapy Resistance and Cell Viability of Breast Cancer Cells by Regulating miR-186 | Full Text | References | PDF (5.4 MB) | EPUB
  • 94 Views
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Article
Knowledge, Attitudes, and Practices of Cancer Patients Towards COVID-19: A Cross-Sectional Study in Central Nepal
Guru Sharan Sah, Gambhir Shrestha, Aayush Dhakal, Rashmi Mulmi, Ashok Sapkota & Shivaji Poudel
Pages: 10173-10180
Published online: 15 Oct 2020
AbstractforKnowledge, Attitudes, and Practices of Cancer Patients Towards COVID-19: A Cross-Sectional Study in Central Nepal | Full Text | References | PDF (285.5 KB) | EPUB
  • 164 Views
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Review

Review Article
Regulatory Networks of LncRNA MALAT-1 in Cancer
Shijian Fu, Yanhong Wang, Hang Li, Leilei Chen & Quanzhong Liu
Pages: 10181-10198
Published online: 15 Oct 2020
AbstractforRegulatory Networks of LncRNA MALAT-1 in Cancer | Full Text | References | PDF (5.9 MB) | EPUB
  • 193 Views
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Original Research

Article
RETRACTED ARTICLE: Knockdown of CircCRIM1 Inhibits HDAC4 to Impede Osteosarcoma Proliferation, Migration, and Invasion and Facilitate Autophagy by Targeting miR-432-5p
Jun Liu, Guang Feng, Zhengwei Li, Rui Li & Peng Xia
Pages: 10199-10210
Published online: 15 Oct 2020
AbstractforRETRACTED ARTICLE: Knockdown of CircCRIM1 Inhibits HDAC4 to Impede Osteosarcoma Proliferation, Migration, and Invasion and Facilitate Autophagy by Targeting miR-432-5p | PDF (6.7 MB)
  • 39 Views
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Article
Synchronous Metastatic Nasopharyngeal Carcinoma: Characteristics and Survival of Patients Adding Definitive Nasopharyngeal-Neck Radiotherapy to Systematic Chemotherapy
Wenjun Liao, Jinlan He, Qiheng Gou, Baofeng Duan, Lei Liu, Ping Ai, Yanchu Li, Kexing Ren & Nianyong Chen
Pages: 10211-10219
Published online: 15 Oct 2020
AbstractforSynchronous Metastatic Nasopharyngeal Carcinoma: Characteristics and Survival of Patients Adding Definitive Nasopharyngeal-Neck Radiotherapy to Systematic Chemotherapy | Full Text | References | PDF (1.1 MB) | EPUB
  • 75 Views
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Article
Elevated Expression of ASXL2 is Associated with Poor Prognosis in Colorectal Cancer by Enhancing Tumorigenesis and Inducing Cell Proliferation
Ran Cui, Ludi Yang, Yiwei Wang, Ming Zhong, Minhao Yu & Bo Chen
Pages: 10221-10228
Published online: 19 Oct 2020
AbstractforElevated Expression of ASXL2 is Associated with Poor Prognosis in Colorectal Cancer by Enhancing Tumorigenesis and Inducing Cell Proliferation | Full Text | References | PDF (3.5 MB) | EPUB
  • 79 Views
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Article
CircRNA circUGGT2 Contributes to Hepatocellular Carcinoma Development via Regulation of the miR-526b-5p/RAB1A Axis
Qingling Kong, Qing Fan, Xianbin Ma, Jian Li & Rong Ma
Pages: 10229-10241
Published online: 15 Oct 2020
AbstractforCircRNA circUGGT2 Contributes to Hepatocellular Carcinoma Development via Regulation of the miR-526b-5p/RAB1A Axis | Full Text | References | PDF (9.6 MB) | EPUB
  • 62 Views
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Article
Overexpression of Cancer Upregulated Gene 2 (CUG2) Decreases Spry2 Through c-Cbl, Leading to Activation of EGFR and β-Catenin Signaling
Natpaphan Yawut, Chutima Kaewpiboon, Phatcharaporn Budluang, Il-Rae Cho, Sirichat Kaowinn, Sang Seok Koh & Young-Hwa Chung
Pages: 10243-10250
Published online: 15 Oct 2020
AbstractforOverexpression of Cancer Upregulated Gene 2 (CUG2) Decreases Spry2 Through c-Cbl, Leading to Activation of EGFR and β-Catenin Signaling | Full Text | References | PDF (2.3 MB) | EPUB
  • 71 Views
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Article
PSA Kinetics as Prognostic Markers of Overall Survival in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Abiraterone Acetate
Sofia España, Maria Ochoa de Olza, Nuria Sala, Josep Maria Piulats, Ulises Ferrandiz, Olatz Etxaniz, Lucia Heras, Oscar Buisan, Juan Carlos Pardo, Jose F Suarez, Pilar Barretina, Josep Comet, Xavier Garcia del Muro, Lauro Sumoy & Albert Font
Pages: 10251-10260
Published online: 16 Oct 2020
AbstractforPSA Kinetics as Prognostic Markers of Overall Survival in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Abiraterone Acetate | Full Text | References | PDF (2.4 MB) | EPUB
  • 118 Views
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Article
Efficacy and Adverse Effects of Self-Expandable Metal Stent Placement for Malignant Duodenal Obstruction: The Papilla of Vater as a Landmark
Chi-Huan Wu, Mu-Hsien Lee, Yung-Kuan Tsou, Wei Teng, Cheng-Hui Lin, Kai-Feng Sung & Nai-Jen Liu
Pages: 10261-10269
Published online: 19 Oct 2020
AbstractforEfficacy and Adverse Effects of Self-Expandable Metal Stent Placement for Malignant Duodenal Obstruction: The Papilla of Vater as a Landmark | Full Text | References | PDF (1 MB) | EPUB
  • 82 Views
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Article
FOLFOX vs FOLFIRI as Second-line of Therapy After Progression to Gemcitabine/Nab-paclitaxel in Patients with Metastatic Pancreatic Cancer
Martina Catalano, Raffaele Conca, Roberto Petrioli, Monica Ramello & Giandomenico Roviello
Pages: 10271-10278
Published online: 19 Oct 2020
AbstractforFOLFOX vs FOLFIRI as Second-line of Therapy After Progression to Gemcitabine/Nab-paclitaxel in Patients with Metastatic Pancreatic Cancer | Full Text | References | PDF (1 MB) | EPUB
  • 88 Views
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Article
Surgical Outcomes of Transvaginal Neobladder-Vaginal Fistula Repair After Radical Cystectomy with Ileal Orthotopic Neobladder: A Case–Control Study
Dong Hyeon Lee & Wan Song
Pages: 10279-10286
Published online: 19 Oct 2020
AbstractforSurgical Outcomes of Transvaginal Neobladder-Vaginal Fistula Repair After Radical Cystectomy with Ileal Orthotopic Neobladder: A Case–Control Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 81 Views
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Article
Implication of Microsatellite Instability in Chinese Cohort of Human Cancers
Meiying Cui, Pan Li, Ying Mao, Lan Zhang, Peiyi Xia, Enjie Liu, Weiwei Wang, Jianying Zhang, Guozhong Jiang & Wencai Li
Pages: 10287-10295
Published online: 19 Oct 2020
AbstractforImplication of Microsatellite Instability in Chinese Cohort of Human Cancers | Full Text | References | PDF (1.6 MB) | EPUB
  • 82 Views
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Case Series

Case Report
Malignant Degeneration of Scars
Anca E Chiriac, Mircea Betiu, Piotr Brzezinski, Beatriz Di Martino Ortiz, Anca Chiriac, Liliana Foia & Doina Azoicai
Pages: 10297-10302
Published online: 19 Oct 2020
AbstractforMalignant Degeneration of Scars | Full Text | References | PDF (2.7 MB) | EPUB
  • 72 Views
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Original Research

Article
Prognostic Nomogram That Predicts Overall Survival of Patients with Distal Cholangiocarcinoma After Pancreatoduodenectomy
Qiao Chen, Jiayi Li, Bao Jin, Xiangan Wu, Yue Shi, Haifeng Xu, Yongchang Zheng, Yingyi Wang, Shunda Du, Xin Lu, Xinting Sang & Yilei Mao
Pages: 10303-10310
Published online: 20 Oct 2020
AbstractforPrognostic Nomogram That Predicts Overall Survival of Patients with Distal Cholangiocarcinoma After Pancreatoduodenectomy | Full Text | References | PDF (2.7 MB) | EPUB
  • 60 Views
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Article
Long Non-Coding RNA NLIPMT as a Tumor Suppressor and Inhibitor of Cell Proliferation and Metastasis in Papillary Thyroid Carcinoma
Fen Zhang, Yangjun Cai, Biyu Diao, Dandan Song, Rongrong Miao, Baodan Zhang, Yingying Hu, Hanqian Zeng & Xiaoqu Hu
Pages: 10311-10319
Published online: 19 Oct 2020
AbstractforLong Non-Coding RNA NLIPMT as a Tumor Suppressor and Inhibitor of Cell Proliferation and Metastasis in Papillary Thyroid Carcinoma | Full Text | References | PDF (4.3 MB) | EPUB
  • 68 Views
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Article
BMI May Be a Prognostic Factor for Local Advanced Rectal Cancer Patients Treated with Long-Term Neoadjuvant Chemoradiotherapy
Hengchang Liu, Ran Wei, Chunxiang Li, Zhixun Zhao, Xu Guan, Ming Yang, Zheng Liu, Xishan Wang & Zheng Jiang
Pages: 10321-10332
Published online: 20 Oct 2020
AbstractforBMI May Be a Prognostic Factor for Local Advanced Rectal Cancer Patients Treated with Long-Term Neoadjuvant Chemoradiotherapy | Full Text | References | PDF (447.4 KB) | EPUB
  • 65 Views
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Article
Clinical Investigation of the Efficacy and Safety of Anlotinib with Immunotherapy in Advanced Non-Small Cell Lung Cancer as Third-Line Therapy: A Retrospective Study
Shengjie Yang, Wenjie Zhang, Qing Chen & Qisen Guo
Pages: 10333-10340
Published online: 19 Oct 2020
AbstractforClinical Investigation of the Efficacy and Safety of Anlotinib with Immunotherapy in Advanced Non-Small Cell Lung Cancer as Third-Line Therapy: A Retrospective Study | Full Text | References | PDF (914.2 KB) | EPUB
  • 65 Views
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Article
A Retrospective Cohort Study on Pretreated Neutrophil-to-Lymphocyte Ratio and Prognosis of Small Cell Lung Cancer: Evidence of Effect Modification by Chemotherapy Regimen
Feiwen Liu, Shaozhang Zhou, Liping Tan, Huiqin Jiang & Yucong Huang
Pages: 10341-10352
Published online: 19 Oct 2020
AbstractforA Retrospective Cohort Study on Pretreated Neutrophil-to-Lymphocyte Ratio and Prognosis of Small Cell Lung Cancer: Evidence of Effect Modification by Chemotherapy Regimen | Full Text | References | PDF (3.7 MB) | EPUB
  • 86 Views
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Article
Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma by Targeting the Epidermal Growth Factor Receptor Combined with Gemcitabine Plus Platinum
Chen Chen, Xuanye Zhang, Yixin Zhou, Sha Fu, Zuan Lin, Shaodong Hong & Li Zhang
Pages: 10353-10360
Published online: 20 Oct 2020
AbstractforTreatment of Recurrent or Metastatic Nasopharyngeal Carcinoma by Targeting the Epidermal Growth Factor Receptor Combined with Gemcitabine Plus Platinum | Full Text | References | PDF (1.1 MB) | EPUB
  • 64 Views
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Review

Review Article
Multiple Primary Lung Cancers: A New Challenge in the Era of Precision Medicine
Lishu Zhao, Chaoyuan Liu, Guiyuan Xie, Fang Wu & Chunhong Hu
Pages: 10361-10374
Published online: 20 Oct 2020
AbstractforMultiple Primary Lung Cancers: A New Challenge in the Era of Precision Medicine | Full Text | References | PDF (400.9 KB) | EPUB
  • 167 Views
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Review Article
GSTM3 Function and Polymorphism in Cancer: Emerging but Promising
Shunda Wang, Jinshou Yang, Lei You, Menghua Dai & Yupei Zhao
Pages: 10377-10388
Published online: 20 Oct 2020
AbstractforGSTM3 Function and Polymorphism in Cancer: Emerging but Promising | Full Text | References | PDF (2.2 MB) | EPUB
  • 166 Views
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Original Research

Article
RETRACTED ARTICLE: Oncolytic Vaccinia Virus-Mediated Antitumor Effect and Cell Proliferation Were Promoted in PTC by Regulating circRNA_103598/miR-23a-3p/IL-6 Axis
Shuilong Zhang, Qiang Wang, Dewei Li, Bo Huang, Xia Hou, Dongliang Wang, Zhifu Xiao, Hongjing Meng, Yuhang Zhang & Lingxiang Dong
Pages: 10389-10396
Published online: 20 Oct 2020
AbstractforRETRACTED ARTICLE: Oncolytic Vaccinia Virus-Mediated Antitumor Effect and Cell Proliferation Were Promoted in PTC by Regulating circRNA_103598/miR-23a-3p/IL-6 Axis | PDF (4.2 MB)
  • 41 Views
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Open Access
Article
LPS Enhances the Chemosensitivity of Oxaliplatin in HT29 Cells via GSDMD-Mediated Pyroptosis
Li-Sha Wu, Yabin Liu, Xiao-wei Wang, Bin Xu, Yan-Ling Lin, Yu Song, Yi Dong, Jin-Lai Liu, Xiang-Jie Wang, Shuang Liu, Peng Kong, Mei Han & Bing-Hui Li
Pages: 10397-10409
Published online: 20 Oct 2020
AbstractforLPS Enhances the Chemosensitivity of Oxaliplatin in HT29 Cells via GSDMD-Mediated Pyroptosis | Full Text | References | PDF (7.1 MB) | EPUB
  • 185 Views
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Open Access

Review

Review Article
Regulatory T Cells in Cancer Immunotherapy: Basic Research Outcomes and Clinical Directions
Guoming Zeng, Libo Jin, Qinsi Ying, Haojie Chen, Murinda Charmaine Thembinkosi, Chunguang Yang, Jinlong Zhao, Hao Ji, Sue Lin, Renyi Peng, Maolan Zhang & Da Sun
Pages: 10411-10421
Published online: 21 Oct 2020
AbstractforRegulatory T Cells in Cancer Immunotherapy: Basic Research Outcomes and Clinical Directions | Full Text | References | PDF (1.9 MB) | EPUB
  • 151 Views
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Open Access
Review Article
Further Understanding of High-Grade Serous Ovarian Carcinogenesis: Potential Therapeutic Targets
Ioannis A Voutsadakis
Pages: 10423-10437
Published online: 21 Oct 2020
AbstractforFurther Understanding of High-Grade Serous Ovarian Carcinogenesis: Potential Therapeutic Targets | Full Text | References | PDF (918.5 KB) | EPUB
  • 105 Views
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Open Access

Original Research

Article
A Model to Predict the Risk of Lymph Node Metastasis in Breast Cancer Based on Clinicopathological Characteristics
Wenxin Chen, Chuan Wang, Fangmeng Fu, Binglin Yang, Changming Chen & Yingming Sun
Pages: 10439-10447
Published online: 22 Oct 2020
AbstractforA Model to Predict the Risk of Lymph Node Metastasis in Breast Cancer Based on Clinicopathological Characteristics | Full Text | References | PDF (1.2 MB) | EPUB
  • 108 Views
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Open Access
Article
ATP6AP2 is Overexpressed in Breast Cancer and Promotes Breast Cancer Progression
Kankan Zhao, Mengchuan Wang & Aiguo Wu
Pages: 10449-10459
Published online: 22 Oct 2020
AbstractforATP6AP2 is Overexpressed in Breast Cancer and Promotes Breast Cancer Progression | Full Text | References | PDF (6.2 MB) | EPUB
  • 99 Views
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Open Access
Article
Analysis of Prognostic Factors and Design of Prognosis Model for Patients with Stage IV Gastric Cancer Following First-Line Palliative Chemotherapy
Qiyin Zhou, Xi Lan, Ni Li, Daozu Yuan & Jiliang Zhang
Pages: 10461-10468
Published online: 22 Oct 2020
AbstractforAnalysis of Prognostic Factors and Design of Prognosis Model for Patients with Stage IV Gastric Cancer Following First-Line Palliative Chemotherapy | Full Text | References | PDF (573.5 KB) | EPUB
  • 72 Views
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Open Access
Article
The Efficacy and Response Predictors of Platinum-Based Neoadjuvant Chemotherapy in Locally Advanced Cervical Cancer
Yuhui Huang, Lin Liu, Jing Cai, Lu Yang, Si Sun, Jing Zhao, Zhoufang Xiong & Zehua Wang
Pages: 10469-10477
Published online: 22 Oct 2020
AbstractforThe Efficacy and Response Predictors of Platinum-Based Neoadjuvant Chemotherapy in Locally Advanced Cervical Cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 107 Views
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Open Access
Article
CA125, CEA, CA19-9, and Heteroploid Cells in Ascites Fluid May Help Diagnose Peritoneal Carcinomatosis in Patients with Gastrointestinal and Ovarian Malignancies
Lin Deng, Shikong Guo, Hong Li, Xianghui You, Yang Song & Haichuan Su
Pages: 10479-10489
Published online: 22 Oct 2020
AbstractforCA125, CEA, CA19-9, and Heteroploid Cells in Ascites Fluid May Help Diagnose Peritoneal Carcinomatosis in Patients with Gastrointestinal and Ovarian Malignancies | Full Text | References | PDF (1.7 MB) | EPUB
  • 76 Views
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Article
Retroperitoneal Extragastrointestinal Stromal Tumors Have a Poor Survival Outcome: A Multicenter Observational Study
Weixian Hu, Chengbin Zheng, Renjie Li, Xingyu Feng, Guoliang Zheng, Zhichao Zheng, Wenjun Xiong, Guosheng Lin, Yongjian Zhou, Wei Wang, Yan Zhao & Yong Li
Pages: 10491-10504
Published online: 23 Oct 2020
AbstractforRetroperitoneal Extragastrointestinal Stromal Tumors Have a Poor Survival Outcome: A Multicenter Observational Study | Full Text | References | PDF (3.9 MB) | EPUB
  • 59 Views
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Article
Circ_0000260 Regulates the Development and Deterioration of Gastric Adenocarcinoma with Cisplatin Resistance by Upregulating MMP11 via Targeting MiR-129-5p
Shicheng Liu, Miao Wu & Mengyin Peng
Pages: 10505-10519
Published online: 23 Oct 2020
AbstractforCirc_0000260 Regulates the Development and Deterioration of Gastric Adenocarcinoma with Cisplatin Resistance by Upregulating MMP11 via Targeting MiR-129-5p | Full Text | References | PDF (10.8 MB) | EPUB
  • 64 Views
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Article
LncRNA CCAL Promotes Angiogenesis Through Regulating the MiR-29b/ANGPTL4 Axis in Osteosarcoma
Shiyi Chen, Mingjia Yang & Shimin Chang
Pages: 10521-10530
Published online: 23 Oct 2020
AbstractforLncRNA CCAL Promotes Angiogenesis Through Regulating the MiR-29b/ANGPTL4 Axis in Osteosarcoma | Full Text | References | PDF (5.5 MB) | EPUB
  • 69 Views
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Open Access
Article
Prognosis of Intravascular Large B Cell Lymphoma (IVLBCL): Analysis of 182 Patients from Global Case Series
Ziyue Liu, Yuelun Zhang, Yicheng Zhu & Wei Zhang
Pages: 10531-10540
Published online: 23 Oct 2020
AbstractforPrognosis of Intravascular Large B Cell Lymphoma (IVLBCL): Analysis of 182 Patients from Global Case Series | Full Text | References | PDF (1.7 MB) | EPUB
  • 169 Views
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Open Access
Article
Long Non-Coding RNA USP2-AS1 Accelerates Cell Proliferation and Migration in Ovarian Cancer by Sponging miR-520d-3p and Up-Regulating KIAA1522
Bingqin Guo, Lan Yu, Yanhong Sun, Nan Yao & Li Ma
Pages: 10541-10550
Published online: 23 Oct 2020
AbstractforLong Non-Coding RNA USP2-AS1 Accelerates Cell Proliferation and Migration in Ovarian Cancer by Sponging miR-520d-3p and Up-Regulating KIAA1522 | Full Text | References | PDF (7.1 MB) | EPUB
  • 66 Views
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Article
A Clinical Comparative Study of Two Different Endometrial Cell Samplers for Evaluation of Endometrial Lesions by Cytopathological Diagnosis
Shulan Lv, Qing Wang, Yan Li, Lanbo Zhao, Yiran Wang, Xue Feng, Lu Han, Kailu Zhang, Panyue Yin, Huilian Hou, Guizhi Shi & Qiling Li
Pages: 10551-10557
Published online: 23 Oct 2020
AbstractforA Clinical Comparative Study of Two Different Endometrial Cell Samplers for Evaluation of Endometrial Lesions by Cytopathological Diagnosis | Full Text | References | PDF (1.3 MB) | EPUB
  • 99 Views
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Open Access
Article
RETRACTED ARTICLE: Inhibition of microRNA-15b-5p Attenuates the Progression of Oral Squamous Cell Carcinoma via Modulating the PTPN4/STAT3 Axis
Xuerong Liu, Yuanyuan Dong & Dan Song
Pages: 10559-10572
Published online: 28 Oct 2020
AbstractforRETRACTED ARTICLE: Inhibition of microRNA-15b-5p Attenuates the Progression of Oral Squamous Cell Carcinoma via Modulating the PTPN4/STAT3 Axis | PDF (13.3 MB)
  • 50 Views
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Open Access
Article
Timing of Adjuvant Chemoradiation in pT1-3N1-2 or pT4aN1 Esophageal Squamous Cell Carcinoma After R0 Esophagectomy
Leilei Wu, Zhenshan Zhang, Shuo Li, Linping Ke, Jinming Yu & Xue Meng
Pages: 10573-10585
Published online: 27 Oct 2020
AbstractforTiming of Adjuvant Chemoradiation in pT1-3N1-2 or pT4aN1 Esophageal Squamous Cell Carcinoma After R0 Esophagectomy | Full Text | References | PDF (3.2 MB) | EPUB
  • 58 Views
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Open Access
Article
Factors Prognostic for Peritoneal Metastases from Colorectal Cancer Treated with Surgery
Chao Chen, Jian Wang, Yamei Zhao, Xiaoxu Ge, Zhanhuai Wang, Shaojun Yu, Yongmao Song, Kefeng Ding, Suzhan Zhang, Shu Zheng & Lifeng Sun
Pages: 10587-10602
Published online: 27 Oct 2020
AbstractforFactors Prognostic for Peritoneal Metastases from Colorectal Cancer Treated with Surgery | Full Text | References | PDF (3.6 MB) | EPUB
  • 66 Views
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Open Access
Article
MRI-Based Radiomic Signature as a Prognostic Biomarker for HER2-Positive Invasive Breast Cancer Treated with NAC
Qin Li, Qin Xiao, Jianwei Li, Shaofeng Duan, He Wang & Yajia Gu
Pages: 10603-10613
Published online: 27 Oct 2020
AbstractforMRI-Based Radiomic Signature as a Prognostic Biomarker for HER2-Positive Invasive Breast Cancer Treated with NAC | Full Text | References | PDF (3.8 MB) | EPUB
  • 108 Views
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Review

Review Article
Treatment Landscape for Patients with HER2-Positive Metastatic Breast Cancer: A Review on Emerging Treatment Options
Simon Peter Gampenrieder, Vanessa Castagnaviz, Gabriel Rinnerthaler & Richard Greil
Pages: 10615-10629
Published online: 27 Oct 2020
AbstractforTreatment Landscape for Patients with HER2-Positive Metastatic Breast Cancer: A Review on Emerging Treatment Options | Full Text | References | PDF (1 MB) | EPUB
  • 184 Views
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Original Research

Article
Outcomes of 596 Advanced Gastric Cancer Patients with Different Numbers of Chemotherapy Lines: The More Chemotherapy Lines, the Better Survival
Li Sun, Huijun Wang, Zhen Liu, Ying Meng, Meiqing Qiu, Yafei Ju & Shu Zhang
Pages: 10631-10638
Published online: 27 Oct 2020
AbstractforOutcomes of 596 Advanced Gastric Cancer Patients with Different Numbers of Chemotherapy Lines: The More Chemotherapy Lines, the Better Survival | Full Text | References | PDF (2.3 MB) | EPUB
  • 71 Views
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Article
CYLD Promotes Apoptosis of Nasopharyngeal Carcinoma Cells by Regulating NDRG1
Yanling Lin, Lingzhi Wang, Wenxiao Luo, Xiaohan Zhou, Yuting Chen, Kaifan Yang, Jinrong Liao, Dehua Wu & Longmei Cai
Pages: 10639-10649
Published online: 27 Oct 2020
AbstractforCYLD Promotes Apoptosis of Nasopharyngeal Carcinoma Cells by Regulating NDRG1 | Full Text | References | PDF (11 MB) | EPUB
  • 79 Views
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Open Access
Article
RETRACTED ARTICLE: Exosome-Encapsulated MicroRNA-21 from Esophageal Squamous Cell Carcinoma Cells Enhances Angiogenesis of Human Umbilical Venous Endothelial Cells by Targeting SPRY1
Huirong Zhuang, Hongjun Wang, Haibo Yang & Hongli Li
Pages: 10651-10667
Published online: 28 Oct 2020
AbstractforRETRACTED ARTICLE: Exosome-Encapsulated MicroRNA-21 from Esophageal Squamous Cell Carcinoma Cells Enhances Angiogenesis of Human Umbilical Venous Endothelial Cells by Targeting SPRY1 | PDF (8.7 MB)
  • 23 Views
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Open Access

Case Report

Case Report
MiR-15b-5b Regulates the Proliferation of Prostate Cancer PC-3 Cells via Targeting LATS2
Zhi-Jie Liu, Shi-Hui Liu, Jun-Ru Li, Xiao-Chuan Bie & Yang Zhou
Pages: 10669-10678
Published online: 28 Oct 2020
AbstractforMiR-15b-5b Regulates the Proliferation of Prostate Cancer PC-3 Cells via Targeting LATS2 | Full Text | References | PDF (4.8 MB) | EPUB
  • 69 Views
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Original Research

Article
circRNA Hsa_circ_0020850 Silence Represses the Development of Lung Adenocarcinoma via Regulating miR-195-5p/IRS2 Axis
Tuye Xin, Shuangshuang Li, Ying Zhang, Xiayizha Kamali, Hui Liu & Tengfei Jia
Pages: 10679-10692
Published online: 28 Oct 2020
AbstractforcircRNA Hsa_circ_0020850 Silence Represses the Development of Lung Adenocarcinoma via Regulating miR-195-5p/IRS2 Axis | Full Text | References | PDF (12.7 MB) | EPUB
  • 68 Views
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Article
LncRNA ADAMTS9-AS1 Restrains the Aggressive Traits of Breast Carcinoma Cells via Sponging miR-513a-5p
Shiqiang Fang, Yu Zhao & Xiaozhen Hu
Pages: 10693-10703
Published online: 28 Oct 2020
AbstractforLncRNA ADAMTS9-AS1 Restrains the Aggressive Traits of Breast Carcinoma Cells via Sponging miR-513a-5p | Full Text | References | PDF (5.1 MB) | EPUB
  • 63 Views
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Article
Trefoil Factor 2 Regulates Proliferation and Apoptosis of Pancreatic Cancer Cells and LPS-Induced Normal Pancreatic Duct Cells by β-Catenin Pathway
Yun Zhou, Yan Zhang & Jia Wang
Pages: 10705-10713
Published online: 29 Oct 2020
AbstractforTrefoil Factor 2 Regulates Proliferation and Apoptosis of Pancreatic Cancer Cells and LPS-Induced Normal Pancreatic Duct Cells by β-Catenin Pathway | Full Text | References | PDF (6.1 MB) | EPUB
  • 72 Views
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Article
Effect of Pelvic Lymphadenectomy on Survival in Patients with Low-Risk Early-Stage Endometrial Cancer Diagnosed Intraoperatively Using Frozen Tissue Sections: A Retrospective Analysis
Caiyan Liu, Jianguo Zhao, Shasha Liu, Yaomei Ma, Yun Yang & Pengpeng Qu
Pages: 10715-10723
Published online: 29 Oct 2020
AbstractforEffect of Pelvic Lymphadenectomy on Survival in Patients with Low-Risk Early-Stage Endometrial Cancer Diagnosed Intraoperatively Using Frozen Tissue Sections: A Retrospective Analysis | Full Text | References | PDF (976.7 KB) | EPUB
  • 81 Views
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Article
Investigating the Effects of RBBP6 Gene Expression on Telomerase Activity in Cervical Cancer Cells
Mpho Mosweu, Lesetja Motadi & Pontsho Moela
Pages: 10725-10734
Published online: 29 Oct 2020
AbstractforInvestigating the Effects of RBBP6 Gene Expression on Telomerase Activity in Cervical Cancer Cells | Full Text | References | PDF (4.4 MB) | EPUB
  • 86 Views
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Article
LncRNA MALAT1 Aggravates the Progression of Non-Small Cell Lung Cancer by Stimulating the Expression of COMMD8 via Targeting miR-613
Shouzhong Wang, Tao Wang, Darui Liu & Haiyan Kong
Pages: 10735-10747
Published online: 29 Oct 2020
AbstractforLncRNA MALAT1 Aggravates the Progression of Non-Small Cell Lung Cancer by Stimulating the Expression of COMMD8 via Targeting miR-613 | Full Text | References | PDF (7.7 MB) | EPUB
  • 103 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA PRR34-AS1 Aggravates the Progression of Hepatocellular Carcinoma by Adsorbing microRNA-498 and Thereby Upregulating FOXO3
Zhaoming Liu, Zhen Li, Binghui Xu, Hao Yao, Shuangyu Qi & Jianxiong Tai
Pages: 10749-10762
Published online: 29 Oct 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA PRR34-AS1 Aggravates the Progression of Hepatocellular Carcinoma by Adsorbing microRNA-498 and Thereby Upregulating FOXO3 | PDF (9.9 MB)
  • 17 Views
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Article
Upregulated Long Non-Coding RNA LL22NC03-N64E9.1 Promotes the Proliferation and Migration of Human Breast Cancer Cells by Silencing Kruppel-Like Factor 2 Expression
Weibin Lian, Xiaohua Jiang, Liangqiang Li, Qinglan Wang, Chengye Hong, Peidong Yang & Debo Chen
Pages: 10763-10770
Published online: 29 Oct 2020
AbstractforUpregulated Long Non-Coding RNA LL22NC03-N64E9.1 Promotes the Proliferation and Migration of Human Breast Cancer Cells by Silencing Kruppel-Like Factor 2 Expression | Full Text | References | PDF (3.9 MB) | EPUB
  • 60 Views
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Article
Propofol Inhibits Proliferation and Invasion of Stomach Cancer Cells by Regulating miR-205/YAP1 Axis
Xiang-Shu Xian, Yu-Tie Wang & Xiao-Meng Jiang
Pages: 10771-10779
Published online: 29 Oct 2020
AbstractforPropofol Inhibits Proliferation and Invasion of Stomach Cancer Cells by Regulating miR-205/YAP1 Axis | Full Text | References | PDF (6.4 MB) | EPUB
  • 62 Views
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Article
A Study of Prognostic Factors of Chinese Patients with Gynecologic Tract Carcinosarcomas Prognosis of Gynecologic Carcinosarcomas
Dan Ye, Hao-Ran Shen & Liangqing Yao
Pages: 10781-10788
Published online: 29 Oct 2020
AbstractforA Study of Prognostic Factors of Chinese Patients with Gynecologic Tract Carcinosarcomas Prognosis of Gynecologic Carcinosarcomas | Full Text | References | PDF (1 MB) | EPUB
  • 68 Views
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Article
Nomogram Including Elastography for Prediction of Contralateral Central Lymph Node Metastasis in Solitary Papillary Thyroid Carcinoma Preoperatively
Ning Li, Ju-hua He, Chao Song, Li-chun Yang, Hong-jiang Zhang & Zhi-hai Li
Pages: 10789-10797
Published online: 29 Oct 2020
AbstractforNomogram Including Elastography for Prediction of Contralateral Central Lymph Node Metastasis in Solitary Papillary Thyroid Carcinoma Preoperatively | Full Text | References | PDF (2.8 MB) | EPUB
  • 65 Views
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Article
The Association Between Smartphone Use and Breast Cancer Risk Among Taiwanese Women: A Case-Control Study
Ya-Wen Shih, Chin-Sheng Hung, Cheng-Chiao Huang, Kuei-Ru Chou, Shu-Fen Niu, Sally Chan & Hsiu-Ting Tsai
Pages: 10799-10807
Published online: 29 Oct 2020
AbstractforThe Association Between Smartphone Use and Breast Cancer Risk Among Taiwanese Women: A Case-Control Study | Full Text | References | PDF (311.4 KB) | EPUB
  • 302 Views
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Article
Antitumor Activity of Cabazitaxel and MSC-TRAIL Derived Extracellular Vesicles in Drug-Resistant Oral Squamous Cell Carcinoma
Yongle Qiu, Jieming Sun, Junping Qiu, Guoling Chen, Xiao Wang, Yaxu Mu, Kunshan Li & Wenjing Wang
Pages: 10809-10820
Published online: 29 Oct 2020
AbstractforAntitumor Activity of Cabazitaxel and MSC-TRAIL Derived Extracellular Vesicles in Drug-Resistant Oral Squamous Cell Carcinoma | Full Text | References | PDF (5.3 MB) | EPUB
  • 161 Views
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Article
The Measurement of the Air-Kerma Rate in Air and a Solid Phantom with Ionization Chambers for a 192Ir HDR Brachytherapy Source
Jing Zeng, Pengpeng Qu, Qingsong Pang & Ping Wang
Pages: 10821-10828
Published online: 29 Oct 2020
AbstractforThe Measurement of the Air-Kerma Rate in Air and a Solid Phantom with Ionization Chambers for a 192Ir HDR Brachytherapy Source | Full Text | References | PDF (1.7 MB) | EPUB
  • 124 Views
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Article
Ultrasound-Targeted Microbubble Destruction Mediated si-CyclinD1 Inhibits the Development of Hepatocellular Carcinoma via Suppression of PI3K/AKT Signaling Pathway
Wei Yan, Li Cheng & Dongmei Zhang
Pages: 10829-10839
Published online: 29 Oct 2020
AbstractforUltrasound-Targeted Microbubble Destruction Mediated si-CyclinD1 Inhibits the Development of Hepatocellular Carcinoma via Suppression of PI3K/AKT Signaling Pathway | Full Text | References | PDF (7 MB) | EPUB
  • 64 Views
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Article
Malignant Ovarian Tumors During Pregnancy: A Multicenter Retrospective Analysis
Liya Wang, Shenjiao Huang, Xiujie Sheng, Chenchen Ren, Qiming Wang, Linqing Yang, Shuping Zhao, Tianmin Xu, Xiaoxin Ma, Ruixia Guo, Pengming Sun, Yang Lin, Yuhong Li, Jiandong Wang & Yudong Wang
Pages: 10841-10848
Published online: 29 Oct 2020
AbstractforMalignant Ovarian Tumors During Pregnancy: A Multicenter Retrospective Analysis | Full Text | References | PDF (298.8 KB) | EPUB
  • 160 Views
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Article
Low Red Blood Cell Count as an Early Indicator for Myometrial Invasion in Women with Endometrioid Endometrial Carcinoma with Metabolic Syndrome
Yao Tong, Xiaoyan Xie, Xiaodan Mao, Huifang Lei, Yaojia Chen & Pengming Sun
Pages: 10849-10859
Published online: 29 Oct 2020
AbstractforLow Red Blood Cell Count as an Early Indicator for Myometrial Invasion in Women with Endometrioid Endometrial Carcinoma with Metabolic Syndrome | Full Text | References | PDF (1.5 MB) | EPUB
  • 83 Views
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Article
Oncogenic Genetic Alterations in Non-Small-Cell Lung Cancer (NSCLC) in Southwestern China
Yuhui Ma, Quan Li, Yaxi Du, Wanlin Chen, Guanqiang Zhao, Xing Liu, Hongsheng Li, Junxi Liu, Zhenghai Shen, Luyao Ma & Yongchun Zhou
Pages: 10861-10874
Published online: 29 Oct 2020
AbstractforOncogenic Genetic Alterations in Non-Small-Cell Lung Cancer (NSCLC) in Southwestern China | Full Text | References | PDF (4.5 MB) | EPUB
  • 105 Views
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Article
Enlarged Mediastinal Lymph Nodes in Computed Tomography are a Valuable Prognostic Factor in Non-Small Cell Lung Cancer Patients with Pathologically Negative Lymph Nodes
Yuansheng Zheng, Yiwei Huang, Guoshu Bi, Zhencong Chen, Tao Lu, Songtao Xu, Cheng Zhan & Qun Wang
Pages: 10875-10886
Published online: 29 Oct 2020
AbstractforEnlarged Mediastinal Lymph Nodes in Computed Tomography are a Valuable Prognostic Factor in Non-Small Cell Lung Cancer Patients with Pathologically Negative Lymph Nodes | Full Text | References | PDF (5.1 MB) | EPUB
  • 66 Views
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Article
CircRAD18 Accelerates the Progression of Acute Myeloid Leukemia by Modulation of miR-206/PRKACB Axis
Yanyan Wang, Te Guo, Quan Liu & Xianfei Xie
Pages: 10887-10896
Published online: 30 Oct 2020
AbstractforCircRAD18 Accelerates the Progression of Acute Myeloid Leukemia by Modulation of miR-206/PRKACB Axis | Full Text | References | PDF (7.3 MB) | EPUB
  • 79 Views
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Article
LncRNA UCA1 Affects the Cell Proliferation, Migration, Invasion and Apoptosis of Hepatic Carcinoma Cells by Targeting MicroRNA-193a-3p
Hong-Zhen Wang, Li Liu, Yan Xu, Guang-Ye Zhang & Yan-Yan Wang
Pages: 10897-10907
Published online: 30 Oct 2020
AbstractforLncRNA UCA1 Affects the Cell Proliferation, Migration, Invasion and Apoptosis of Hepatic Carcinoma Cells by Targeting MicroRNA-193a-3p | Full Text | References | PDF (5.2 MB) | EPUB
  • 66 Views
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Article
Coactosin-Like Protein (COTL1) Promotes Glioblastoma (GBM) Growth in vitro and in vivo
Shike Shao, Yongjun Fan, Chongpei Zhong, Xianlong Zhu & Jiaqiu Zhu
Pages: 10909-10917
Published online: 30 Oct 2020
AbstractforCoactosin-Like Protein (COTL1) Promotes Glioblastoma (GBM) Growth in vitro and in vivo | Full Text | References | PDF (6.5 MB) | EPUB
  • 70 Views
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Article
Diameter of Superior Rectal Vein – CT Predictor of KRAS Mutation in Rectal Carcinoma
Chenyu Song, Bingqi Shen, Zhi Dong, Zhenzhen Fan, Ling Xu, Zi-Ping Li, Yin Li & Shi-Ting Feng
Pages: 10919-10928
Published online: 30 Oct 2020
AbstractforDiameter of Superior Rectal Vein – CT Predictor of KRAS Mutation in Rectal Carcinoma | Full Text | References | PDF (1.1 MB) | EPUB
  • 60 Views
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Article
Down-Regulation of NOX4 Expression in Dorsal Horn of Spinal Cord Could Alleviate Cancer-Induced Bone Pain in Rats by Reducing Oxidative Stress Response
Hao Long, Hui Zheng, Long Ai, Kamil Osman & Zhigang Liu
Pages: 10929-10938
Published online: 30 Oct 2020
AbstractforDown-Regulation of NOX4 Expression in Dorsal Horn of Spinal Cord Could Alleviate Cancer-Induced Bone Pain in Rats by Reducing Oxidative Stress Response | Full Text | References | PDF (5.4 MB) | EPUB
  • 101 Views
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Article
PD-L1 Predicts Poor Prognosis in Surgically Resected Limited Stage Small-Cell Lung Cancer
Xiao Fu, Zhiyan Liu, Luochengling Xiang, Mengjie Liu, Xiaoqiang Zheng, Jingjing Wang, Na Liu, Huan Gao, Aimin Jiang, Yujuan Yang, Xuan Liang, Zhiping Ruan, Tao Tian & Yu Yao
Pages: 10939-10948
Published online: 30 Oct 2020
AbstractforPD-L1 Predicts Poor Prognosis in Surgically Resected Limited Stage Small-Cell Lung Cancer | Full Text | References | PDF (3.7 MB) | EPUB
  • 92 Views
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Review

Review Article
Matrilysins and Stromelysins in Pathogenesis and Diagnostics of Cancers
Barbara Maria Piskór, Andrzej Przylipiak, Emilia Dąbrowska, Marek Niczyporuk & Sławomir Ławicki
Pages: 10949-10964
Published online: 30 Oct 2020
AbstractforMatrilysins and Stromelysins in Pathogenesis and Diagnostics of Cancers | Full Text | References | PDF (401.2 KB) | EPUB
  • 106 Views
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Original Research

Article
RETRACTED ARTICLE: miR-302e Suppresses Glioma Progression by Targeting VEGFA
Yunpeng Xie, Xin Liu, Tiemin Hu & Weixing Wang
Pages: 10965-10974
Published online: 30 Oct 2020
AbstractforRETRACTED ARTICLE: miR-302e Suppresses Glioma Progression by Targeting VEGFA | PDF (5.7 MB)
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Article
MiR-490-3p Inhibits the Malignant Progression of Lung Adenocarcinoma
Zhiyong Li, Danfeng Jiang & Sheng Yang
Pages: 10975-10984
Published online: 30 Oct 2020
AbstractforMiR-490-3p Inhibits the Malignant Progression of Lung Adenocarcinoma | Full Text | References | PDF (3.7 MB) | EPUB
  • 66 Views
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Article
The Diagnostic and Prognostic Value of Serum lncRNA NEAT1 in Colorectal Cancer
Yong Wang, Dongsheng Zhang, Chuan Zhang & Yueming Sun
Pages: 10985-10992
Published online: 02 Nov 2020
AbstractforThe Diagnostic and Prognostic Value of Serum lncRNA NEAT1 in Colorectal Cancer | Full Text | References | PDF (3 MB) | EPUB
  • 86 Views
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Article
Circ_0109046 Promotes the Progression of Endometrial Cancer via Regulating miR-136/HMGA2 Axis
Yanping Shi, Li Jia & Hongli Wen
Pages: 10993-11003
Published online: 02 Nov 2020
AbstractforCirc_0109046 Promotes the Progression of Endometrial Cancer via Regulating miR-136/HMGA2 Axis | Full Text | References | PDF (7.4 MB) | EPUB
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Article
Long-Chain Non-Coding SOX21-AS1 Promotes Proliferation and Migration of Breast Cancer Cells Through the PI3K/AKT Signaling Pathway
Xiu-Yun Sheng, Cheng-Hong Wang, Chun-Feng Wang & Hong-Yan Xu
Pages: 11005-11014
Published online: 02 Nov 2020
AbstractforLong-Chain Non-Coding SOX21-AS1 Promotes Proliferation and Migration of Breast Cancer Cells Through the PI3K/AKT Signaling Pathway | Full Text | References | PDF (4.5 MB) | EPUB
  • 67 Views
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Article
Development and Validation of Nomograms for Predicting Cancer-Specific Survival in Elderly Patients with Intrahepatic Cholangiocarcinoma After Liver Resection: A Competing Risk Analysis
Tao Wang, Jinfu Zhang, Wanxiang Wang, Xianwei Yang, Junjie Kong, Shu Shen & Wentao Wang
Pages: 11015-11029
Published online: 02 Nov 2020
AbstractforDevelopment and Validation of Nomograms for Predicting Cancer-Specific Survival in Elderly Patients with Intrahepatic Cholangiocarcinoma After Liver Resection: A Competing Risk Analysis | Full Text | References | PDF (5.6 MB) | EPUB
  • 71 Views
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Article
Circ-ATP5H Induces Hepatitis B Virus Replication and Expression by Regulating miR-138-5p/TNFAIP3 Axis
Wenxiu Jiang, Lili Wang, Yajuan Zhang & Hongliang Li
Pages: 11031-11040
Published online: 02 Nov 2020
AbstractforCirc-ATP5H Induces Hepatitis B Virus Replication and Expression by Regulating miR-138-5p/TNFAIP3 Axis | Full Text | References | PDF (5.7 MB) | EPUB
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Article
LINC00518 Interference Inhibits Non–Small Cell Lung Cancer by Upregulating miR216b-5p Expression
Yuanyuan Ren, Huadong Zhu & Song Han
Pages: 11041-11050
Published online: 02 Nov 2020
AbstractforLINC00518 Interference Inhibits Non–Small Cell Lung Cancer by Upregulating miR216b-5p Expression | Full Text | References | PDF (7.3 MB) | EPUB
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Article
Knockdown of PDIA6 Inhibits Cell Proliferation and Enhances the Chemosensitivity in Gastric Cancer Cells
Chao Yan, Xiaolei Song, Su Wang, Jinhai Wang & Lu Li
Pages: 11051-11062
Published online: 02 Nov 2020
AbstractforKnockdown of PDIA6 Inhibits Cell Proliferation and Enhances the Chemosensitivity in Gastric Cancer Cells | Full Text | References | PDF (9.2 MB) | EPUB
  • 89 Views
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Article
The Association Between RAPSN Methylation in Peripheral Blood and Early Stage Lung Cancer Detected in Case–Control Cohort
Rong Qiao, Feifei Di, Jun Wang, Yujie Wei, Yanman Zhang, Tian Xu, Yue Wang, Wanjian Gu, Baohui Han & Rongxi Yang
Pages: 11063-11075
Published online: 02 Nov 2020
AbstractforThe Association Between RAPSN Methylation in Peripheral Blood and Early Stage Lung Cancer Detected in Case–Control Cohort | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Mannose Impairs Lung Adenocarcinoma Growth and Enhances the Sensitivity of A549 Cells to Carboplatin
Jun Sha, Dandan Cao, Rui Cui, Lu Xia, Xin Hua, Yuan Lu & Shuhua Han
Pages: 11077-11083
Published online: 03 Nov 2020
AbstractforMannose Impairs Lung Adenocarcinoma Growth and Enhances the Sensitivity of A549 Cells to Carboplatin | Full Text | References | PDF (3.1 MB) | EPUB
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Article
Pathogenic Heteroplasmic Somatic Mitochondrial DNA Mutation Confers Platinum-Resistance and Recurrence of High-Grade Serous Ovarian Cancer
Jing Ni, Yan Wang, Xianzhong Cheng, Fang Teng, Congyang Wang, Suping Han, Xiaoxiang Chen & Wenwen Guo
Pages: 11085-11093
Published online: 02 Nov 2020
AbstractforPathogenic Heteroplasmic Somatic Mitochondrial DNA Mutation Confers Platinum-Resistance and Recurrence of High-Grade Serous Ovarian Cancer | Full Text | References | PDF (2.3 MB) | EPUB
  • 79 Views
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Article
Overexpression of MTFR2 Predicts Poor Prognosis of Breast Cancer
Wenjie Lu, Rukun Zang, Yuanna Du, Xinghua Li, Hongwei Li, Chuan Liu, Yipeng Song, Yuncheng Li & Yang Wang
Pages: 11095-11102
Published online: 02 Nov 2020
AbstractforOverexpression of MTFR2 Predicts Poor Prognosis of Breast Cancer | Full Text | References | PDF (1.8 MB) | EPUB
  • 85 Views
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Article
LncRNA TUG1 Promotes Growth and Metastasis of Cholangiocarcinoma Cells by Inhibiting miR-29a
Wei Yuan Hao, Li Wen Guo, Jun Luo, Guo Liang Shao & Jia Ping Zheng
Pages: 11103-11111
Published online: 02 Nov 2020
AbstractforLncRNA TUG1 Promotes Growth and Metastasis of Cholangiocarcinoma Cells by Inhibiting miR-29a | Full Text | References | PDF (4.7 MB) | EPUB
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Article
Effect of Immune Checkpoint Inhibitors Plus Chemotherapy on Advanced Gastric Cancer Patients with Elevated Serum AFP or Hepatoid Adenocarcinoma
Wei Li, Qian Li, Yiyi Yu, Yan Wang, Erbao Chen, Lingli Chen, Zhiming Wang, Yuehong Cui & Tianshu Liu
Pages: 11113-11119
Published online: 02 Nov 2020
AbstractforEffect of Immune Checkpoint Inhibitors Plus Chemotherapy on Advanced Gastric Cancer Patients with Elevated Serum AFP or Hepatoid Adenocarcinoma | Full Text | References | PDF (2.2 MB) | EPUB
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Article
Xiaoai Jiedu Recipe suppresses hepatocellular carcinogenesis through the miR‐200b-3p /Notch1 axis
Wenli Qiu, Zhongqiu Wang, Rong Chen, Haibo Shi, Yanxia Ma, Hongli Zhou, Muhan Li, Wenting Li, Haibin Chen & Hongguang Zhou
Pages: 11121-11131
Published online: 02 Nov 2020
AbstractforXiaoai Jiedu Recipe suppresses hepatocellular carcinogenesis through the miR‐200b-3p /Notch1 axis | Full Text | References | PDF (5.8 MB) | EPUB
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Article
Efficacy and Safety of Anlotinib for Elderly Patients with Previously Treated Extensive-Stage SCLC and the Prognostic Significance of Common Adverse Reactions
Peng-Fei Song, Ning Xu & Qin Li
Pages: 11133-11143
Published online: 02 Nov 2020
AbstractforEfficacy and Safety of Anlotinib for Elderly Patients with Previously Treated Extensive-Stage SCLC and the Prognostic Significance of Common Adverse Reactions | Full Text | References | PDF (2.5 MB) | EPUB
  • 84 Views
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Article
Ropivacaine Inhibits Cell Proliferation, Migration and Invasion, Whereas Induces Oxidative Stress and Cell Apoptosis by circSCAF11/miR-145-5p Axis in Glioma
Danqin Yin, Li Liu, Zhengyuan Shi, Lihui Zhang & Yan Yang
Pages: 11145-11155
Published online: 03 Nov 2020
AbstractforRopivacaine Inhibits Cell Proliferation, Migration and Invasion, Whereas Induces Oxidative Stress and Cell Apoptosis by circSCAF11/miR-145-5p Axis in Glioma | Full Text | References | PDF (6.6 MB) | EPUB
  • 82 Views
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Article
The Long Noncoding RNA Linc01833 Enhances Lung Adenocarcinoma Progression via MiR-519e-3p/S100A4 Axis
Yuan Zhang, Wenhua Li, Zongxiang Lin, Jingfeng Hu, Jingpu Wang, Yukai Ren, BoChong Wei, Yuxia Fan & Yang Yang
Pages: 11157-11167
Published online: 03 Nov 2020
AbstractforThe Long Noncoding RNA Linc01833 Enhances Lung Adenocarcinoma Progression via MiR-519e-3p/S100A4 Axis | Full Text | References | PDF (5.5 MB) | EPUB
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Article
Circ_0072995 Promotes Cell Carcinogenesis via Up-Regulating miR-149-5p-Mediated SHMT2 in Breast Cancer
Chuang Qi, Xianxiong Qin, Zuozhi Zhou, Yan Wang, Qin Yang & Tianzhi Liao
Pages: 11169-11181
Published online: 03 Nov 2020
AbstractforCirc_0072995 Promotes Cell Carcinogenesis via Up-Regulating miR-149-5p-Mediated SHMT2 in Breast Cancer | Full Text | References | PDF (8.4 MB) | EPUB
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Article
NARFIB: A Novel Prognostic Score Based on the Neutrophil-to-Albumin Ratio and Fibrinogen Can Predict the Prognosis of Gastrointestinal Stromal Tumors
Rui Li, Zhen Sun, Shibo Song, Xiuwen He, Xiaolei Shi, Zhe Li & Jinghai Song
Pages: 11183-11190
Published online: 03 Nov 2020
AbstractforNARFIB: A Novel Prognostic Score Based on the Neutrophil-to-Albumin Ratio and Fibrinogen Can Predict the Prognosis of Gastrointestinal Stromal Tumors | Full Text | References | PDF (1.1 MB) | EPUB
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Article
A Nomogram to Predict the Probability of Breast Intraductal Tumors in Patients with Nipple Discharge: A Real-World Study Based on Our 13-Year Clinical Experience
Bin Wang, Siyuan Jiang, Lizhe Zhu, Wei Sheng, Yan Qiao, Huimin Zhang, Jian Zhang, Yang Liu, Na Hao, Xiaoxia Ma, Can Zhou & Yu Ren
Pages: 11191-11201
Published online: 03 Nov 2020
AbstractforA Nomogram to Predict the Probability of Breast Intraductal Tumors in Patients with Nipple Discharge: A Real-World Study Based on Our 13-Year Clinical Experience | Full Text | References | PDF (2.2 MB) | EPUB
  • 64 Views
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Article
CAB39 Promotes the Proliferation of Nasopharyngeal Carcinoma CNE-1 Cells via Up-Regulating p-JNK
Lifen Peng, Hailan Yan, Shuyi Qi & Lifei Deng
Pages: 11203-11209
Published online: 04 Nov 2020
AbstractforCAB39 Promotes the Proliferation of Nasopharyngeal Carcinoma CNE-1 Cells via Up-Regulating p-JNK | Full Text | References | PDF (2 MB) | EPUB
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Article
The Expression of VEGF and CD31 in Endometrial Lesions and Its Associations with Blood Flow Parameters of Transvaginal 3D Power Doppler Ultrasonography: A Preliminary Study
Meijuan Liu, Li Cai, Qifan Li, Xiaoran Chen, Lingyun Gao & Lei Jiang
Pages: 11211-11218
Published online: 04 Nov 2020
AbstractforThe Expression of VEGF and CD31 in Endometrial Lesions and Its Associations with Blood Flow Parameters of Transvaginal 3D Power Doppler Ultrasonography: A Preliminary Study | Full Text | References | PDF (710 KB) | EPUB
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Article
MicroRNA-802 Suppresses Tumorigenesis of Colorectal Cancer via Regulating UBN2
Tao Yang, Qiuying Guo, Dongsheng Li, Guang Bai, Hongzhi Sun & Wei Wang
Pages: 11219-11230
Published online: 04 Nov 2020
AbstractforMicroRNA-802 Suppresses Tumorigenesis of Colorectal Cancer via Regulating UBN2 | Full Text | References | PDF (5.8 MB) | EPUB
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Article
HNRNPCL1, PRAMEF1, CFAP74, and DFFB: Common Potential Biomarkers for Sporadic and Suspected Lynch Syndrome Endometrial Cancer
Yuan Gao, Xiuping Zhang, Tian Wang, Ye Zhang, Qingxuan Wang & Yuanjing Hu
Pages: 11231-11241
Published online: 04 Nov 2020
AbstractforHNRNPCL1, PRAMEF1, CFAP74, and DFFB: Common Potential Biomarkers for Sporadic and Suspected Lynch Syndrome Endometrial Cancer | Full Text | References | PDF (5.1 MB) | EPUB
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Article
Circ_0061825 Acts as a miR-593-3p Sponge to Promote Breast Cancer Progression by Regulating FGFR3 Expression
Jiping Xie, Yi Wan, Min Zhang, Zeyu Jin & Yongqiang Yao
Pages: 11243-11255
Published online: 04 Nov 2020
AbstractforCirc_0061825 Acts as a miR-593-3p Sponge to Promote Breast Cancer Progression by Regulating FGFR3 Expression | Full Text | References | PDF (10.5 MB) | EPUB
  • 72 Views
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Article
Down-Regulation of Circ_0032833 Sensitizes Colorectal Cancer to 5-Fluorouracil and Oxaliplatin Partly Depending on the Regulation of miR-125-5p and MSI1
Shouchao Li & Sheng Zheng
Pages: 11257-11269
Published online: 04 Nov 2020
AbstractforDown-Regulation of Circ_0032833 Sensitizes Colorectal Cancer to 5-Fluorouracil and Oxaliplatin Partly Depending on the Regulation of miR-125-5p and MSI1 | Full Text | References | PDF (8.7 MB) | EPUB
  • 100 Views
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Article
Inhibition of CDK1 Reverses the Resistance of 5-Fu in Colorectal Cancer
Yiping Zhu, Kai Li, Jieling Zhang, Lu Wang, Lili Sheng & Liang Yan
Pages: 11271-11283
Published online: 04 Nov 2020
AbstractforInhibition of CDK1 Reverses the Resistance of 5-Fu in Colorectal Cancer | Full Text | References | PDF (9.4 MB) | EPUB
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Article
LncRNA Lnc712 Promotes Tumorigenesis in Hepatocellular Carcinoma by Targeting miR-142-3p/Bach-1 Axis
Dan Cui & Caifang Ni
Pages: 11285-11294
Published online: 05 Nov 2020
AbstractforLncRNA Lnc712 Promotes Tumorigenesis in Hepatocellular Carcinoma by Targeting miR-142-3p/Bach-1 Axis | Full Text | References | PDF (7.2 MB) | EPUB
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Article
Risk Stratification Based on Synchronous Neoplasia and Clinical Physicochemical Characteristics Predicts a Higher Incidence of Metachronous Advanced Neoplasia in Patients Undergoing Colorectal Resection for Colorectal Cancer
Yanan Tian, Yu Xin & Shuai Li
Pages: 11295-11307
Published online: 05 Nov 2020
AbstractforRisk Stratification Based on Synchronous Neoplasia and Clinical Physicochemical Characteristics Predicts a Higher Incidence of Metachronous Advanced Neoplasia in Patients Undergoing Colorectal Resection for Colorectal Cancer | Full Text | References | PDF (3.6 MB) | EPUB
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Article
Tanshinone IIA Suppresses Glioma Cell Proliferation, Migration and Invasion Both in vitro and in vivo Partially Through miR-16-5p/Talin-1 (TLN1) Axis
Shihao You, Xianghui He, Mei Wang, Lina Mao & Lu Zhang
Pages: 11309-11320
Published online: 06 Nov 2020
AbstractforTanshinone IIA Suppresses Glioma Cell Proliferation, Migration and Invasion Both in vitro and in vivo Partially Through miR-16-5p/Talin-1 (TLN1) Axis | Full Text | References | PDF (9.7 MB) | EPUB
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Article
Effect of the Up-Regulation of Circular RNA Hsa_circ_0069767 Derived from C-KIT on the Biological Behavior of Multiple Myeloma Cells
Fang Chen, Xiaohui Wang, Shuang Fu, Shaokun Wang, Yu Fu, Zhuogang Liu & Jihong Zhang
Pages: 11321-11331
Published online: 06 Nov 2020
AbstractforEffect of the Up-Regulation of Circular RNA Hsa_circ_0069767 Derived from C-KIT on the Biological Behavior of Multiple Myeloma Cells | Full Text | References | PDF (8.2 MB) | EPUB
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Article
Whole-Brain Radiotherapy Can Improve the Survival of Patients with Multiple Brain Metastases from Non-Small Cell Lung Cancer Treated by Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors
Cheng Chen, Yan Wu, Bao Ling Liu, Hong Wei Wang, Jian Hua Ma & Ju Ying Zhou
Pages: 11333-11340
Published online: 06 Nov 2020
AbstractforWhole-Brain Radiotherapy Can Improve the Survival of Patients with Multiple Brain Metastases from Non-Small Cell Lung Cancer Treated by Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors | Full Text | References | PDF (1.1 MB) | EPUB
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Article
miR-141 Promotes Colon Cancer Cell Proliferation by Targeted PHLPP2 Expression Inhibitionn
Fazhuang Fang, Ling Cheng, Xiaotang Wu, Minfeng Ye & Huizhong Zhang
Pages: 11341-11350
Published online: 06 Nov 2020
AbstractformiR-141 Promotes Colon Cancer Cell Proliferation by Targeted PHLPP2 Expression Inhibitionn | Full Text | References | PDF (3.6 MB) | EPUB
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Case Series

Case Report
The Effect and Safety of Anti-PD-1 Single/Combination Therapy in Refractory Thymic Carcinoma: A Case-Series Study
Wei Jin, Jian-Chun Duan, Zhi-Jie Wang, Lin Lin, Hua Bai, Jie Wang & Li Feng
Pages: 11351-11358
Published online: 06 Nov 2020
AbstractforThe Effect and Safety of Anti-PD-1 Single/Combination Therapy in Refractory Thymic Carcinoma: A Case-Series Study | Full Text | References | PDF (1.2 MB) | EPUB
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Original Research

Article
RETRACTED ARTICLE: LncRNA MALAT1 Promotes Survival of Epithelial Ovarian Cancer Cells by Downregulating miR-145-5p
Ke Wang, Ye Zhao & Yi-Min Wang
Pages: 11359-11369
Published online: 06 Nov 2020
AbstractforRETRACTED ARTICLE: LncRNA MALAT1 Promotes Survival of Epithelial Ovarian Cancer Cells by Downregulating miR-145-5p | PDF (3.1 MB)
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Article
Phosphorylated MAPK14 Promotes the Proliferation and Migration of Bladder Cancer Cells by Maintaining RUNX2 Protein Abundance
Junlong Liu, Xiuyue Yu, Bitian Liu, Hongyuan Yu & Zhenhua Li
Pages: 11371-11382
Published online: 06 Nov 2020
AbstractforPhosphorylated MAPK14 Promotes the Proliferation and Migration of Bladder Cancer Cells by Maintaining RUNX2 Protein Abundance | Full Text | References | PDF (6.6 MB) | EPUB
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Article
Cetuximab Plus Chemotherapy versus Chemotherapy Alone in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Cost-Effectiveness Analysis
Yitian Lang & Deshi Dong
Pages: 11383-11390
Published online: 06 Nov 2020
AbstractforCetuximab Plus Chemotherapy versus Chemotherapy Alone in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Cost-Effectiveness Analysis | Full Text | References | PDF (739.7 KB) | EPUB
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Article
Association Between Intermediate-Acting Neuromuscular-Blocking Agents and Short-Term Postoperative Outcomes in Patients with Gastric Cancer
Lingxia Niu, Chunlin Yao, Yu Wang, Yan Sun, Juan Xu, Yun Lin & Shanglong Yao
Pages: 11391-11402
Published online: 06 Nov 2020
AbstractforAssociation Between Intermediate-Acting Neuromuscular-Blocking Agents and Short-Term Postoperative Outcomes in Patients with Gastric Cancer | Full Text | References | PDF (463.6 KB) | EPUB
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Article
Overexpression of lncRNA TATDN1 Promotes Cancer Cell Proliferation in Triple Negative Breast Cancer by Regulating miR-26b Methylation
Quanyi Long, Hongjiang Li, Yuan Fan & Jia Zhang
Pages: 11403-11410
Published online: 06 Nov 2020
AbstractforOverexpression of lncRNA TATDN1 Promotes Cancer Cell Proliferation in Triple Negative Breast Cancer by Regulating miR-26b Methylation | Full Text | References | PDF (5.2 MB) | EPUB
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Article
Plasmacytoid Dendritic Cell Infiltration in Acute Myeloid Leukemia
Lidan Zhu, Ping Wang, Wei Zhang, Qiong Li, Jingkang Xiong, Jiali Li, Xiaojuan Deng, Yao Liu, Chao Yang, Peiyan Kong, Xiangui Peng, Jiang F Zhong, Jun Rao & Xi Zhang
Pages: 11411-11419
Published online: 06 Nov 2020
AbstractforPlasmacytoid Dendritic Cell Infiltration in Acute Myeloid Leukemia | Full Text | References | PDF (3.4 MB) | EPUB
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Erratum

Correction
CELSR1 Acts as an Oncogene Regulated by miR-199a-5p in Glioma [Erratum]
Page: 11421
Published online: 06 Nov 2020
CitationforCELSR1 Acts as an Oncogene Regulated by miR-199a-5p in Glioma [Erratum] | Full Text | PDF (157.4 KB) | EPUB
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Original Research

Article
lncRNA SNHG1 Promotes Progression of Cervical Cancer Through miR-195/NEK2 Axis
Yuan Yuan Ji, Man Meng & Ye Miao
Pages: 11423-11433
Published online: 09 Nov 2020
AbstractforlncRNA SNHG1 Promotes Progression of Cervical Cancer Through miR-195/NEK2 Axis | Full Text | References | PDF (4.2 MB) | EPUB
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Article
Baohuoside I via mTOR Apoptotic Signaling to Inhibit Glioma Cell Growth
Yangyang Guo, Cheng Wang, Minghui Jiang, Hengyue Zhu, Min Weng, Linxiao Sun & Yanlei Zhang
Pages: 11435-11444
Published online: 10 Nov 2020
AbstractforBaohuoside I via mTOR Apoptotic Signaling to Inhibit Glioma Cell Growth | Full Text | References | PDF (12.5 MB) | EPUB
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Article
Long Noncoding RNA PCAT18 Upregulates SPRR3 to Promote Colorectal Cancer Progression by Binding to miR-759
Daqing Yang, Rizeng Li, Jianfu Xia, Wencai Li, Lili Ma, Lechi Ye & Haibo Xue
Pages: 11445-11452
Published online: 09 Nov 2020
AbstractforLong Noncoding RNA PCAT18 Upregulates SPRR3 to Promote Colorectal Cancer Progression by Binding to miR-759 | Full Text | References | PDF (6 MB) | EPUB
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Article
Regulating DSC2 Expression Affects the Proliferation and Apoptosis of Prostate Cancer Cells
Feng Jiang & Pengfei Wu
Pages: 11453-11462
Published online: 09 Nov 2020
AbstractforRegulating DSC2 Expression Affects the Proliferation and Apoptosis of Prostate Cancer Cells | Full Text | References | PDF (9.9 MB) | EPUB
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Article
Prognostic Significance of Inflammatory Biomarkers in Patients with Breast Cancer Skeletal Metastases
Yuan Wang, Guilin Huang & Zhigang Li
Pages: 11463-11475
Published online: 09 Nov 2020
AbstractforPrognostic Significance of Inflammatory Biomarkers in Patients with Breast Cancer Skeletal Metastases | Full Text | References | PDF (1.4 MB) | EPUB
  • 75 Views
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Article
CircPVT1 Promoted the Progression of Breast Cancer by Regulating MiR-29a-3p-Mediated AGR2-HIF-1α Pathway
Jing Wang, Kuo Huang, Lang Shi, Qingyong Zhang & Shengchu Zhang
Pages: 11477-11490
Published online: 12 Nov 2020
AbstractforCircPVT1 Promoted the Progression of Breast Cancer by Regulating MiR-29a-3p-Mediated AGR2-HIF-1α Pathway | Full Text | References | PDF (7.6 MB) | EPUB
  • 113 Views
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Article
miR-105 Promotes the Progression and Predicts the Prognosis for Oral Squamous Cell Carcinoma (OSCC)
Hong-Yu Zhang & Jian-Hui Ma
Pages: 11491-11499
Published online: 10 Nov 2020
AbstractformiR-105 Promotes the Progression and Predicts the Prognosis for Oral Squamous Cell Carcinoma (OSCC) | Full Text | References | PDF (3.4 MB) | EPUB
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Article
Prognostic Significance of a Novel Score Model Based on Preoperative Indicators in Patients with Breast Cancer Spine Metastases (BCSM)
Chenglong Zhao, Yao Wang, Xiaopan Cai, Wei Xu, Dongsheng Wang, Ting Wang, Qi Jia, Haiyi Gong, Haitao Sun, Zhipeng Wu & Jianru Xiao
Pages: 11501-11513
Published online: 10 Nov 2020
AbstractforPrognostic Significance of a Novel Score Model Based on Preoperative Indicators in Patients with Breast Cancer Spine Metastases (BCSM) | Full Text | References | PDF (4.1 MB) | EPUB
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Article
Characteristics and Management of TP53-Mutated Diffuse Large B-Cell Lymphoma Patients
Yan Qin, Shiyu Jiang, Peng Liu, Jianliang Yang, Sheng Yang, Xiaohui He, Shengyu Zhou, Lin Gui, Jing Lin, Xinhua Du, Yuting Yi, Yan Sun & Yuankai Shi
Pages: 11515-11522
Published online: 10 Nov 2020
AbstractforCharacteristics and Management of TP53-Mutated Diffuse Large B-Cell Lymphoma Patients | Full Text | References | PDF (1.5 MB) | EPUB
  • 101 Views
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Article
Efficacy and Safety of Apatinib Treatment for Patients with Advanced Intrahepatic Cholangiocarcinoma
Guohe Lin, Bicheng Wang, Xiuwei Wu, Tong Sun, Lili Chen, Canliang Lu & Nianfei Wang
Pages: 11523-11526
Published online: 10 Nov 2020
AbstractforEfficacy and Safety of Apatinib Treatment for Patients with Advanced Intrahepatic Cholangiocarcinoma | Full Text | References | PDF (396.6 KB) | EPUB
  • 46 Views
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Article
CircSEC31A Promotes the Malignant Progression of Non-Small Cell Lung Cancer Through Regulating SEC31A Expression via Sponging miR-376a
Fengfeng Cheng, Jing Yu, Xiaoying Zhang, Zongyan Dai & Aiju Fang
Pages: 11527-11539
Published online: 10 Nov 2020
AbstractforCircSEC31A Promotes the Malignant Progression of Non-Small Cell Lung Cancer Through Regulating SEC31A Expression via Sponging miR-376a | Full Text | References | PDF (9.7 MB) | EPUB
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Article
Predictive Value of Some Inflammatory Indexes in the Survival and Toxicity of Nasopharyngeal Carcinoma
Yu-Yuan Han, Kai-Hua Chen, Ying Guan, Li Chen, Man-Ru Lin, Si-Kai Nong & Xiao-Dong Zhu
Pages: 11541-11551
Published online: 11 Nov 2020
AbstractforPredictive Value of Some Inflammatory Indexes in the Survival and Toxicity of Nasopharyngeal Carcinoma | Full Text | References | PDF (2.8 MB) | EPUB
  • 68 Views
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Article
Analyses of Potential Driver and Passenger Bacteria in Human Colorectal Cancer
Yijia Wang, Chunze Zhang, Shaobin Hou, Xiaojing Wu, Jun Liu & Xuehua Wan
Pages: 11553-11561
Published online: 12 Nov 2020
AbstractforAnalyses of Potential Driver and Passenger Bacteria in Human Colorectal Cancer | Full Text | References | PDF (4.4 MB) | EPUB
  • 157 Views
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Article
Hypofractionated Radiotherapy for 35 Patients with Adrenal Metastases: A Single-Institution Experience
Ruizhi Zhao, Yuchao Ma, Siran Yang, Qingfeng Liu, Yuan Tang, Kai Wang, Ye Zhang, Nan Bi, Hongmei Zhang, Junlin Yi, Yexiong Li, Jingwei Luo & Jianping Xiao
Pages: 11563-11571
Published online: 12 Nov 2020
AbstractforHypofractionated Radiotherapy for 35 Patients with Adrenal Metastases: A Single-Institution Experience | Full Text | References | PDF (2.2 MB) | EPUB
  • 53 Views
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Article
Azoxystrobin Reduces Oral Carcinogenesis by Suppressing Mitochondrial Complex III Activity and Inducing Apoptosis
Hui Chen, Lingyu Li, Yunping Lu, Yajun Shen, Min Zhang, Lihua Ge, Min Wang, Jing Yang, Zhenchuan Tian & Xiaofei Tang
Pages: 11573-11583
Published online: 12 Nov 2020
AbstractforAzoxystrobin Reduces Oral Carcinogenesis by Suppressing Mitochondrial Complex III Activity and Inducing Apoptosis | Full Text | References | PDF (4.4 MB) | EPUB
  • 124 Views
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Article
PD-L1 Expression is Highly Associated with Tumor-Associated Macrophage Infiltration in Nasopharyngeal Carcinoma
Rui Deng, Juan Lu, Xiong Liu, Xiao-Hong Peng, Jie Wang & Xiang-Ping Li
Pages: 11585-11596
Published online: 12 Nov 2020
AbstractforPD-L1 Expression is Highly Associated with Tumor-Associated Macrophage Infiltration in Nasopharyngeal Carcinoma | Full Text | References | PDF (3.2 MB) | EPUB
  • 99 Views
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Article
miR-124-3p Regulates FGF2–EGFR Pathway to Overcome Pemetrexed Resistance in Lung Adenocarcinoma Cells by Targeting MGAT5
Jundong Cai, Jiuning Huang, Wulong Wang, Jing Zeng & Ping Wang
Pages: 11597-11609
Published online: 13 Nov 2020
AbstractformiR-124-3p Regulates FGF2–EGFR Pathway to Overcome Pemetrexed Resistance in Lung Adenocarcinoma Cells by Targeting MGAT5 | Full Text | References | PDF (9.8 MB) | EPUB
  • 62 Views
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Article
Predictors of Resilience Among Parents of Children with Cancer: Cross-Sectional Study
Esubalew Mezgebu, Emebet Berhan & Leul Deribe
Pages: 11611-11621
Published online: 16 Nov 2020
AbstractforPredictors of Resilience Among Parents of Children with Cancer: Cross-Sectional Study | Full Text | References | PDF (472.1 KB) | EPUB
  • 463 Views
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Article
Dedifferentiated Endometrioid Carcinomas with Neuroendocrine Differentiation: A Clinicopathological and Immunohistochemical Study of Three Cases
Feng Zhou, Xiaofei Zhang, Hao Chen & Wenxin Zheng
Pages: 11623-11629
Published online: 13 Nov 2020
AbstractforDedifferentiated Endometrioid Carcinomas with Neuroendocrine Differentiation: A Clinicopathological and Immunohistochemical Study of Three Cases | Full Text | References | PDF (840.3 KB) | EPUB
  • 70 Views
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Article
Is There a Survival Benefit for Patients with Advanced Ovarian Clear Cell Carcinoma Who Complete More Than 6 Cycles of Postoperative Chemotherapy?
Jing Wang, Yuying Shi, Yan Liu, Wei Li, Hong Jiang & Hongbing Cai
Pages: 11631-11638
Published online: 13 Nov 2020
AbstractforIs There a Survival Benefit for Patients with Advanced Ovarian Clear Cell Carcinoma Who Complete More Than 6 Cycles of Postoperative Chemotherapy? | Full Text | References | PDF (2.3 MB) | EPUB
  • 64 Views
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Article
LncRNA-IUR Sponges miR-24 to Upregulate P53 in Laryngeal Squamous Cell Carcinoma
Cen Wei, Huaqing Wei, Xun Wu, Guangyao Nong, Chenglin Wu, Jinli Lee, Ning Meng, Dahai Yu, Jiping Su, Mengzhu Guo, Jiangyuan Qin & Xuemin Fan
Pages: 11639-11647
Published online: 16 Nov 2020
AbstractforLncRNA-IUR Sponges miR-24 to Upregulate P53 in Laryngeal Squamous Cell Carcinoma | Full Text | References | PDF (5.7 MB) | EPUB
  • 75 Views
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Article
GJA1 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Colorectal Cancer
Wenjun Hu, Shuchun Li, Sen Zhang, Bowen Xie, Minhua Zheng, Jing Sun, Xiao Yang & Lu Zang
Pages: 11649-11661
Published online: 16 Nov 2020
AbstractforGJA1 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Colorectal Cancer | Full Text | References | PDF (9.4 MB) | EPUB
  • 107 Views
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Article
Short-Term Quality of Life, Functional Status, and Their Predictors in Tongue Cancer Patients After Anterolateral Thigh Free Flap Reconstruction: A Single-Center, Prospective, Comparative Study
Roba Tamer, Yongyi Chen, Xianghua Xu, Chanjuan Xie & Joel Swai
Pages: 11663-11673
Published online: 16 Nov 2020
AbstractforShort-Term Quality of Life, Functional Status, and Their Predictors in Tongue Cancer Patients After Anterolateral Thigh Free Flap Reconstruction: A Single-Center, Prospective, Comparative Study | Full Text | References | PDF (666.1 KB) | EPUB
  • 105 Views
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Open Access

Retraction

Retraction
Long Non-Coding RNA Cancer Susceptibility 9 (CASC9) Up-Regulates the Expression of ERBB2 by Inhibiting miR-193a-5p in Colorectal Cancer [Retraction]
Page: 11675
Published online: 16 Nov 2020
CitationforLong Non-Coding RNA Cancer Susceptibility 9 (CASC9) Up-Regulates the Expression of ERBB2 by Inhibiting miR-193a-5p in Colorectal Cancer [Retraction] | Full Text | PDF (165.7 KB) | EPUB
  • 51 Views
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Original Research

Article
Bioinformatics Analysis Identifies a Novel Role of GINS1 Gene in Colorectal Cancer
Fanqin Bu, Xiaojian Zhu, Jinfeng Zhu, Zitao Liu, Ting Wu, Chen Luo, Kang Lin & Jun Huang
Pages: 11677-11687
Published online: 17 Nov 2020
AbstractforBioinformatics Analysis Identifies a Novel Role of GINS1 Gene in Colorectal Cancer | Full Text | References | PDF (11.8 MB) | EPUB
  • 182 Views
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Article
Prognostic Factors After Hepatectomy for Gastric Adenocarcinoma Liver Metastases: Desmoplastic Growth Pattern as the Key to Improved Overall Survival
Maria José Temido, Rui Caetano Oliveira, Ricardo Martins, Marco Serôdio, Beatriz Costa, César Carvalho, Eva Santos, Luís Ferreira, Paulo Teixeira, Maria Augusta Cipriano, José Guilherme Tralhão & Henrique Alexandrino
Pages: 11689-11699
Published online: 17 Nov 2020
AbstractforPrognostic Factors After Hepatectomy for Gastric Adenocarcinoma Liver Metastases: Desmoplastic Growth Pattern as the Key to Improved Overall Survival | Full Text | References | PDF (860.3 KB) | EPUB
  • 63 Views
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Article
Circ_0062020 Knockdown Strengthens the Radiosensitivity of Prostate Cancer Cells
Haitao Li, Yunlai Zhi, Chunyan Ma, Qianqian Shen, Fanghu Sun & Chengkuan Cai
Pages: 11701-11712
Published online: 17 Nov 2020
AbstractforCirc_0062020 Knockdown Strengthens the Radiosensitivity of Prostate Cancer Cells | Full Text | References | PDF (6.5 MB) | EPUB
  • 76 Views
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Article
Nomogram to Predict Preoperative Occult Peritoneal Metastasis of Gastrointestinal Stromal Tumors (GIST) Based on Imaging and Inflammatory Indexes
Shao-Jun Xu, Guo-Sheng Lin, Hong-Jian Ling, Ren-Jie Guo, Jie Chen, Yi-Ming Liao, Tao Lin & Yong-Jian Zhou
Pages: 11713-11721
Published online: 18 Nov 2020
AbstractforNomogram to Predict Preoperative Occult Peritoneal Metastasis of Gastrointestinal Stromal Tumors (GIST) Based on Imaging and Inflammatory Indexes | Full Text | References | PDF (3.3 MB) | EPUB
  • 70 Views
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Open Access
Article
Up-Regulation of miR-26a-5p Inhibits E2F7 to Regulate the Progression of Renal Carcinoma Cells
Chuanyu Cheng, Liang Guo, Yaohui Ma, Zhe Wang, Xinpeng Fan & Zhongjie Shan
Pages: 11723-11733
Published online: 17 Nov 2020
AbstractforUp-Regulation of miR-26a-5p Inhibits E2F7 to Regulate the Progression of Renal Carcinoma Cells | Full Text | References | PDF (10.1 MB) | EPUB
  • 62 Views
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Article
Combined Diagnostic Significance of Preoperative Serum β2-Microglobulin and Routine Blood Test in Patients with High-grade Glioma and Solitary Brain Metastasis
Liwen Li, Xiaomin Bu, Bin Wu, Shuyuan Zhang, Kai Jin, Liang Xia & Caixing Sun
Pages: 11735-11742
Published online: 17 Nov 2020
AbstractforCombined Diagnostic Significance of Preoperative Serum β2-Microglobulin and Routine Blood Test in Patients with High-grade Glioma and Solitary Brain Metastasis | Full Text | References | PDF (2.3 MB) | EPUB
  • 72 Views
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Article
Association Between RBC Antigen Allo-Antibodies and Immune-Related Adverse Events During Immune Checkpoint Inhibitor Treatment for Advanced Cancers
Natasha A Jain, Songzhu Zhao, Lai Wei, Kerry A Rogers, Gregory A Otterson, Tzu-Fei Wang & Dwight H Owen
Pages: 11743-11749
Published online: 17 Nov 2020
AbstractforAssociation Between RBC Antigen Allo-Antibodies and Immune-Related Adverse Events During Immune Checkpoint Inhibitor Treatment for Advanced Cancers | Full Text | References | PDF (280 KB) | EPUB
  • 77 Views
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Article
Magnetic Resonance Imaging (MRI) Phenotypes May Provide Additional Information for Risk Stratification for Encapsulated Papillary Carcinoma of the Breast
Wen-Jie Tang, Yun-Shi Liang, Jing Yan, Yue Hu, Mei-Li Sun, Guo-Shun Liu, Xiao-Huan Pan, Xin-Hua Wei, Xin-Qing Jiang & Yuan Guo
Pages: 11751-11760
Published online: 17 Nov 2020
AbstractforMagnetic Resonance Imaging (MRI) Phenotypes May Provide Additional Information for Risk Stratification for Encapsulated Papillary Carcinoma of the Breast | Full Text | References | PDF (4.8 MB) | EPUB
  • 73 Views
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Article
Imaging Pattern of Diffuse Intrapulmonary Metastases in Lung Cancer Was Associated with Poor Prognosis to Epidermal Growth Factor Receptor Inhibitors
Yang Fu, Yuan Tang, Yue Zheng, Yue-Yun Chen, Ye Hong, Pei-Pei Wang, Qing Li, Ting Liu & Zhen-Yu Ding
Pages: 11761-11772
Published online: 17 Nov 2020
AbstractforImaging Pattern of Diffuse Intrapulmonary Metastases in Lung Cancer Was Associated with Poor Prognosis to Epidermal Growth Factor Receptor Inhibitors | Full Text | References | PDF (8 MB) | EPUB
  • 58 Views
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Article
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling
Mao-Hua Ping
Pages: 11773-11782
Published online: 17 Nov 2020
AbstractforHyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling | Full Text | References | PDF (10.4 MB) | EPUB
  • 80 Views
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Article
Development and Validation of a Nomogram Model to Predict Acute Kidney Disease After Nephrectomy in Patients with Renal Cell Carcinoma
Xiao-Ying Hu, Dong-Wei Liu, Ying-Jin Qiao, Xuan Zheng, Jia-Yu Duan, Shao-Kang Pan & Zhang-Sou Liu
Pages: 11783-11791
Published online: 17 Nov 2020
AbstractforDevelopment and Validation of a Nomogram Model to Predict Acute Kidney Disease After Nephrectomy in Patients with Renal Cell Carcinoma | Full Text | References | PDF (421.4 KB) | EPUB
  • 73 Views
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Article
Economic Burden and Predictors of Cost Variability Among Adult Cancer Patients at Comprehensive Specialized Hospitals in West Amhara, Northwest Ethiopia, 2019
Asebe Hagos, Mezgebu Yitayal, Adane Kebede & Ayal Debie
Pages: 11793-11802
Published online: 18 Nov 2020
AbstractforEconomic Burden and Predictors of Cost Variability Among Adult Cancer Patients at Comprehensive Specialized Hospitals in West Amhara, Northwest Ethiopia, 2019 | Full Text | References | PDF (361.6 KB) | EPUB
  • 148 Views
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Article
Antitumor Efficacy of Oncolytic Herpes Virus Type 1 Armed with GM-CSF in Murine Uveal Melanoma Xenografts
Sisi Liu, Fusheng Liu, Mingwei Zhao & Junwen Zhang
Pages: 11803-11812
Published online: 18 Nov 2020
AbstractforAntitumor Efficacy of Oncolytic Herpes Virus Type 1 Armed with GM-CSF in Murine Uveal Melanoma Xenografts | Full Text | References | PDF (7.1 MB) | EPUB
  • 216 Views
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Article
Short-Term and Long-Term Outcomes Following Transhiatal versus Right Thoracoabdominal Resection of Siewert Type II Adenocarcinoma of the Esophagogastric Junction
Jiadi Xing, Maoxing Liu, Kai Xu, Pin Gao, Fei Tan, Zhendan Yao, Nan Zhang, Hong Yang, Chenghai Zhang, Ming Cui & Xiangqian Su
Pages: 11813-11821
Published online: 19 Nov 2020
AbstractforShort-Term and Long-Term Outcomes Following Transhiatal versus Right Thoracoabdominal Resection of Siewert Type II Adenocarcinoma of the Esophagogastric Junction | Full Text | References | PDF (1.2 MB) | EPUB
  • 64 Views
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Article
Adipose-Derived Stem Cells Promote Proliferation and Invasion in Cervical Cancer by Targeting the HGF/c-MET Pathway
Yongning Zhai, Wangfei Wu, Xiaowei Xi & Rongbin Yu
Pages: 11823-11832
Published online: 18 Nov 2020
AbstractforAdipose-Derived Stem Cells Promote Proliferation and Invasion in Cervical Cancer by Targeting the HGF/c-MET Pathway | Full Text | References | PDF (6.6 MB) | EPUB
  • 105 Views
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Article
The Combination of Icotinib Hydrochloride and Fluzoparib Enhances the Radiosensitivity of Biliary Tract Cancer Cells
Linggang Zhu, Chu Zhu, Xuanxuan Wang, Hai Liu, Yanhong Zhu & Xiaonan Sun
Pages: 11833-11844
Published online: 19 Nov 2020
AbstractforThe Combination of Icotinib Hydrochloride and Fluzoparib Enhances the Radiosensitivity of Biliary Tract Cancer Cells | Full Text | References | PDF (6.9 MB) | EPUB
  • 72 Views
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Article
LncRNA NEAT1 Promotes the Progression of Gastric Cancer Through Modifying the miR-1224-5p/RSF1 Signaling Axis
Luoluo Yang, Min Wang & Ping He
Pages: 11845-11855
Published online: 19 Nov 2020
AbstractforLncRNA NEAT1 Promotes the Progression of Gastric Cancer Through Modifying the miR-1224-5p/RSF1 Signaling Axis | Full Text | References | PDF (5.7 MB) | EPUB
  • 64 Views
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Article
Combined Therapy Can Improve the Outcomes of Breast Cancer with Isolated Supraclavicular Lymph Node Involvement
Tianyi Ma, Yan Mao & Haibo Wang
Pages: 11857-11869
Published online: 19 Nov 2020
AbstractforCombined Therapy Can Improve the Outcomes of Breast Cancer with Isolated Supraclavicular Lymph Node Involvement | Full Text | References | PDF (1.5 MB) | EPUB
  • 70 Views
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Article
Circ_0002232 Acts as a Potential Biomarker for AML and Reveals a Potential ceRNA Network of Circ_0002232/miR-92a-3p/PTEN
Xiao-Yu Su, Qian Zhao, Jin-Ming Ke, De-Hong Wu, Xin Zhu, Jiang Lin & Zhao-Qun Deng
Pages: 11871-11881
Published online: 19 Nov 2020
AbstractforCirc_0002232 Acts as a Potential Biomarker for AML and Reveals a Potential ceRNA Network of Circ_0002232/miR-92a-3p/PTEN | Full Text | References | PDF (3.2 MB) | EPUB
  • 56 Views
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Article
Silencing circSLC19A1 Inhibits Prostate Cancer Cell Proliferation, Migration and Invasion Through Regulating miR-326/MAPK1 Axis
Banggao Huang, Danhong Zhou, Xinmian Huang, Xiaobo Xu & Zhihui Xu
Pages: 11883-11895
Published online: 19 Nov 2020
AbstractforSilencing circSLC19A1 Inhibits Prostate Cancer Cell Proliferation, Migration and Invasion Through Regulating miR-326/MAPK1 Axis | Full Text | References | PDF (7.6 MB) | EPUB
  • 64 Views
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Article
Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer
Zhaoxia Wang, Fengyan Li, Meiyan Wei, Sanyuan Zhang & Tong Wang
Pages: 11897-11908
Published online: 19 Nov 2020
AbstractforCircadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer | Full Text | References | PDF (10.5 MB) | EPUB
  • 120 Views
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Article
The Influence of Venous Characteristics on Peripherally Inserted Central Catheter-Related Symptomatic Venous Thrombosis in Cancer Patients
Guo-Dong Wang, Hong-Zhi Wang, Yan-Fen Shen, Jing Dong, Xin-Peng Wang, Xiao-Zheng Wang II, Yuan-Yuan Zheng, Jie Chen & Shuang-Shuang Guo
Pages: 11909-11920
Published online: 20 Nov 2020
AbstractforThe Influence of Venous Characteristics on Peripherally Inserted Central Catheter-Related Symptomatic Venous Thrombosis in Cancer Patients | Full Text | References | PDF (1.3 MB) | EPUB
  • 113 Views
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Article
Efficacy of the Preoperative Albumin–Bilirubin Grade for Predicting Survival and Outcomes of Postoperative Chemotherapy for Advanced Gastric Cancer
Ce Zhu, Xiang Wang, Sian Chen, Xinxin Yang, Jing Sun, Bujian Pan, Weiteng Zhang, Xiaodong Chen & Yingpeng Huang
Pages: 11921-11932
Published online: 20 Nov 2020
AbstractforEfficacy of the Preoperative Albumin–Bilirubin Grade for Predicting Survival and Outcomes of Postoperative Chemotherapy for Advanced Gastric Cancer | Full Text | References | PDF (2.6 MB) | EPUB
  • 98 Views
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Article
MiR-582-5p Inhibits Bladder Cancer-Genesis by Suppressing TTK Expression
Yudong Tian, Yanbin Guan, Yang Su, Wenjian Luo, Guo Yang & Yu Zhang
Pages: 11933-11944
Published online: 20 Nov 2020
AbstractforMiR-582-5p Inhibits Bladder Cancer-Genesis by Suppressing TTK Expression | Full Text | References | PDF (5.9 MB) | EPUB
  • 81 Views
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Article
Endovascular Management of Intractable Nasopharyngeal Hemorrhage in Patients Irradiated for Nasopharyngeal Carcinoma: A Twelve-Year Experience
Yingliang Wang, Xiangjun Dong, Chen Zhou, Qin Shi, Jiacheng Liu & Bin Xiong
Pages: 11945-11952
Published online: 20 Nov 2020
AbstractforEndovascular Management of Intractable Nasopharyngeal Hemorrhage in Patients Irradiated for Nasopharyngeal Carcinoma: A Twelve-Year Experience | Full Text | References | PDF (1.6 MB) | EPUB
  • 63 Views
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Article
The N6-Methyladenosine (m6A) Methylation Gene YTHDF1 Reveals a Potential Diagnostic Role for Gastric Cancer
Tong Liu, Sheng Yang, Yan-ping Cheng, Xiao-ling Kong, Dan-dan Du, Xian Wang, Yun-fei Bai, Li-hong Yin, Yue-pu Pu & Ge-yu Liang
Pages: 11953-11964
Published online: 20 Nov 2020
AbstractforThe N6-Methyladenosine (m6A) Methylation Gene YTHDF1 Reveals a Potential Diagnostic Role for Gastric Cancer | Full Text | References | PDF (5.6 MB) | EPUB
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Review

Review Article
Biomolecular Factors Represented by Bcl-2, p53, and Tumor-Infiltrating Lymphocytes Predict Response for Adjuvant Anthracycline Chemotherapy in Patients with Early Triple-Negative Breast Cancer
Xenia Elena Bacinschi, Anca Zgura, Inga Safta & Rodica Anghel
Pages: 11965-11971
Published online: 20 Nov 2020
AbstractforBiomolecular Factors Represented by Bcl-2, p53, and Tumor-Infiltrating Lymphocytes Predict Response for Adjuvant Anthracycline Chemotherapy in Patients with Early Triple-Negative Breast Cancer | Full Text | References | PDF (826.2 KB) | EPUB
  • 86 Views
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Original Research

Article
Comprehensive Characterization of Stage IIIA Non-Small Cell Lung Carcinoma
Neetu Singh, Archana Mishra, Dinesh Kumar Sahu, Mayank Jain, Hari Shyam, Ratnesh Kumar Tripathi, Pratap Shankar, Anil Kumar, Nawazish Alam, Riddhi Jaiswal & Shailendra Kumar
Pages: 11973-11988
Published online: 20 Nov 2020
AbstractforComprehensive Characterization of Stage IIIA Non-Small Cell Lung Carcinoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 76 Views
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Article
The Preoperative Enhanced Degree of Contrast-enhanced CT Images: A Potential Independent Predictor in Gastric Adenocarcinoma Patients After Radical Gastrectomy
Xinxin Wang, Huajun Ye, Ye Yan, Jiansheng Wu, Na Wang & Mengjun Chen
Pages: 11989-11999
Published online: 23 Nov 2020
AbstractforThe Preoperative Enhanced Degree of Contrast-enhanced CT Images: A Potential Independent Predictor in Gastric Adenocarcinoma Patients After Radical Gastrectomy | Full Text | References | PDF (4.2 MB) | EPUB
  • 56 Views
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Article
LncRNA TMPO-AS1 Promotes Proliferation and Invasion by Sponging miR-383-5p in Glioma Cells
Guoyuan Liu, Haiying Yang, Lei Cao, Kun Han & Guobin Li
Pages: 12001-12009
Published online: 23 Nov 2020
AbstractforLncRNA TMPO-AS1 Promotes Proliferation and Invasion by Sponging miR-383-5p in Glioma Cells | Full Text | References | PDF (9 MB) | EPUB
  • 58 Views
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Article
RETRACTED ARTICLE: SNHG1 Promotes Malignant Progression of Glioma by Targeting miR-140-5p and Regulating PI3K/AKT Pathway
Ren-Duan Cai, Chao-Cai Zhang, Li-Li Xie, Peng-Cheng Wang, Chui-Xue Huang, Jian-Long Chen & Hong-Tao Lv
Pages: 12011-12020
Published online: 24 Nov 2020
AbstractforRETRACTED ARTICLE: SNHG1 Promotes Malignant Progression of Glioma by Targeting miR-140-5p and Regulating PI3K/AKT Pathway | PDF (7.4 MB)
  • 17 Views
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Article
Clinical Features and Short-Term Outcomes in COVID-19-Infected Patients with Cancer
Yong Wang, Ben-Jie Shan, Xia-Bo Shen, Chang-Cheng Zheng, Jin-Quan Wang, Gui-Ling Li & Yue-Yin Pan
Pages: 12021-12028
Published online: 23 Nov 2020
AbstractforClinical Features and Short-Term Outcomes in COVID-19-Infected Patients with Cancer | Full Text | References | PDF (1.6 MB) | EPUB
  • 59 Views
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Article
Risk Factors and Clavien–Dindo Classification of Postoperative Complications After Laparoscopic and Open Gastrectomies for Gastric Cancer: A Single-Center, Large Sample, Retrospective Cohort Study
Bo Lian, Jie Chen, Zhengyan Li, Gang Ji, Shiqi Wang, Qingchuan Zhao & Mengbin Li
Pages: 12029-12039
Published online: 23 Nov 2020
AbstractforRisk Factors and Clavien–Dindo Classification of Postoperative Complications After Laparoscopic and Open Gastrectomies for Gastric Cancer: A Single-Center, Large Sample, Retrospective Cohort Study | Full Text | References | PDF (518.9 KB) | EPUB
  • 107 Views
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Article
Psychological Resilience and Health-Related Quality of Life in Swedish Women with Newly Diagnosed Breast Cancer
Åsa Mohlin, Ulrika Axelsson, Pär-Ola Bendahl, Carl Borrebaeck, Cecilia Hegardt, Per Johnsson, Ingalill Rahm Hallberg & Lisa Rydén
Pages: 12041-12051
Published online: 24 Nov 2020
AbstractforPsychological Resilience and Health-Related Quality of Life in Swedish Women with Newly Diagnosed Breast Cancer | Full Text | References | PDF (918.4 KB) | EPUB
  • 250 Views
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Article
RETRACTED ARTICLE: Long Non-Coding RNA C1QTNF1 Antisense RNA 1 Upregulates Hexokinase 2 by Sponging microRNA-484 to Promote the Malignancy of Colorectal Cancer
Shifeng Jin, Yi Liu, Wenjing Wang & Ze Li
Pages: 12053-12066
Published online: 24 Nov 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA C1QTNF1 Antisense RNA 1 Upregulates Hexokinase 2 by Sponging microRNA-484 to Promote the Malignancy of Colorectal Cancer | PDF (9.1 MB)
  • 25 Views
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Article
Extracellular Collagen Mediates Osteosarcoma Progression Through an Integrin α2β1/JAK/STAT3 Signaling Pathway
Daiqing Wei, Cui Li, Junwu Ye, Feifan Xiang & Juncai Liu
Pages: 12067-12075
Published online: 24 Nov 2020
AbstractforExtracellular Collagen Mediates Osteosarcoma Progression Through an Integrin α2β1/JAK/STAT3 Signaling Pathway | Full Text | References | PDF (3.8 MB) | EPUB
  • 102 Views
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Article
The Prognostic Comparison Between Hepatocellular Carcinoma with Portal Vein Tumor Thrombus and Bile Duct Cancer Thrombus After Liver Resection
Xin Yang, Ying Zhu, Xia Zhao, Jian-hua Li, Da Xu, Hu-Liang Jia & Ju-bo Zhang
Pages: 12077-12086
Published online: 24 Nov 2020
AbstractforThe Prognostic Comparison Between Hepatocellular Carcinoma with Portal Vein Tumor Thrombus and Bile Duct Cancer Thrombus After Liver Resection | Full Text | References | PDF (1.8 MB) | EPUB
  • 86 Views
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Article
Effect of miR-515-5p on Proliferation and Drug Sensitivity of Retinoblastoma Cells
Xiang Wen Yuan, Ting Qin Yan & Huilin Tong
Pages: 12087-12098
Published online: 24 Nov 2020
AbstractforEffect of miR-515-5p on Proliferation and Drug Sensitivity of Retinoblastoma Cells | Full Text | References | PDF (5.8 MB) | EPUB
  • 70 Views
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Article
Lobaplatin-Based Hyperthermic Intraperitoneal Chemotherapy for Patients with Peritoneal Metastasis from Appendiceal and Colorectal Cancer: Safety and Efficacy Profiles
Wei Pei, Sicheng Zhou, Jing Zhang, Haitao Zhou, Haipeng Chen, Jianjun Bi, Zhaoxu Zheng, Zheng Liu, Zheng Jiang, Zheng Wang, Qian Liu, Xishan Wang, Jianwei Liang & Qiang Feng
Pages: 12099-12110
Published online: 24 Nov 2020
AbstractforLobaplatin-Based Hyperthermic Intraperitoneal Chemotherapy for Patients with Peritoneal Metastasis from Appendiceal and Colorectal Cancer: Safety and Efficacy Profiles | Full Text | References | PDF (3 MB) | EPUB
  • 72 Views
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Article
Expression and Bioinformatics-Based Functional Analysis of UAP1 in Lung Adenocarcinoma
Xianghai Wang, Xingwu Chen & Hongbing Liu
Pages: 12111-12121
Published online: 25 Nov 2020
AbstractforExpression and Bioinformatics-Based Functional Analysis of UAP1 in Lung Adenocarcinoma | Full Text | References | PDF (6.9 MB) | EPUB
  • 97 Views
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Article
Bioinformatics Analysis and Validation Identify CDK1 and MAD2L1 as Prognostic Markers of Rhabdomyosarcoma
Suying Lu, Chengtao Sun, Huimou Chen, Chao Zhang, Wei Li, Liuhong Wu, Jia Zhu, Feifei Sun, Junting Huang, Juan Wang, Zijun Zhen, Ruiqing Cai, Xiaofei Sun, Yizhuo Zhang & Xing Zhang
Pages: 12123-12136
Published online: 26 Nov 2020
AbstractforBioinformatics Analysis and Validation Identify CDK1 and MAD2L1 as Prognostic Markers of Rhabdomyosarcoma | Full Text | References | PDF (8.9 MB) | EPUB
  • 99 Views
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Article
Preoperative Immune Prognostic Index Can Predict the Clinical Outcomes of Patients with Gallbladder Cancer: Single-Center Experience
Lejia Sun, Dongyue Wang, Mengyuan Zhang, Yukai Jin, Bao Jin, Haifeng Xu, Shunda Du, Yiyao Xu, Haitao Zhao, Xin Lu, Xinting Sang, Shouxian Zhong, Huayu Yang & Yilei Mao
Pages: 12137-12150
Published online: 25 Nov 2020
AbstractforPreoperative Immune Prognostic Index Can Predict the Clinical Outcomes of Patients with Gallbladder Cancer: Single-Center Experience | Full Text | References | PDF (2.8 MB) | EPUB
  • 58 Views
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Article
Long Intergenic Non-Protein Coding RNA 01089 Weakens Tumor Proliferation, Migration, and Invasion by Sponging miR-3187-3p in Non-Small Cell Lung Cancer
Dongdong Zhang, Xingdong Cai, Songwang Cai, Wenyou Chen & Chuang Hu
Pages: 12151-12162
Published online: 25 Nov 2020
AbstractforLong Intergenic Non-Protein Coding RNA 01089 Weakens Tumor Proliferation, Migration, and Invasion by Sponging miR-3187-3p in Non-Small Cell Lung Cancer | Full Text | References | PDF (10.4 MB) | EPUB
  • 79 Views
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Article
The Role of Contrast-Enhanced Ultrasound in Evaluating Gestational Trophoblastic Neoplasia: A Preliminary Study
Na Su, Chenyang Zhao, Bo Zhang, Zhenhong Qi, Bin Gao, Zhenzhen Liu, Meng Yang, Yuxin Jiang & Qing Dai
Pages: 12163-12174
Published online: 26 Nov 2020
AbstractforThe Role of Contrast-Enhanced Ultrasound in Evaluating Gestational Trophoblastic Neoplasia: A Preliminary Study | Full Text | References | PDF (1.5 MB) | EPUB
  • 57 Views
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Article
Development of Mobile Application for Dynamically Monitoring the Risk of Prostate Cancer and Clinicopathology
Hui Wang, Lidong Chen, Jun Zhou, Sheng Tai & Chaozhao Liang
Pages: 12175-12184
Published online: 26 Nov 2020
AbstractforDevelopment of Mobile Application for Dynamically Monitoring the Risk of Prostate Cancer and Clinicopathology | Full Text | References | PDF (3.6 MB) | EPUB
  • 94 Views
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Article
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB
Chunxiao Wang, Zesheng Shi, Zhongshi Hong, Jianpeng Pan, Zhichuan Chen, Chengzhi Qiu, Haibin Zhuang & Xuecong Zheng
Pages: 12185-12195
Published online: 26 Nov 2020
AbstractforMicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB | Full Text | References | PDF (8.8 MB) | EPUB
  • 83 Views
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Article
Procalcitonin Levels in Post TACE Infection
Shugao Han, Yao Ye, Jianjun Wu, Bin Li, Guangqiang Zhang, Kai Jin, Rui Tang, Wei Huang, Ming Chao & Kefeng Ding
Pages: 12197-12203
Published online: 26 Nov 2020
AbstractforProcalcitonin Levels in Post TACE Infection | Full Text | References | PDF (1.4 MB) | EPUB
  • 64 Views
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Article
YAP Triggers Bladder Cancer Proliferation by Affecting the MAPK Pathway
Dandan Qiu, Yan Zhu & Zhicheng Cong
Pages: 12205-12214
Published online: 27 Nov 2020
AbstractforYAP Triggers Bladder Cancer Proliferation by Affecting the MAPK Pathway | Full Text | References | PDF (16.9 MB) | EPUB
  • 121 Views
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Article
MicroRNA-200c Nanoparticles Sensitized Gastric Cancer Cells to Radiotherapy by Regulating PD-L1 Expression and EMT
Lingyu Qian, Fangcen Liu, Yanhong Chu, Qingqing Zhai, Xiao Wei, Jie Shao, Rutian Li, Qiuping Xu, Lixia Yu, Baorui Liu & Qin Liu
Pages: 12215-12223
Published online: 27 Nov 2020
AbstractforMicroRNA-200c Nanoparticles Sensitized Gastric Cancer Cells to Radiotherapy by Regulating PD-L1 Expression and EMT | Full Text | References | PDF (4 MB) | EPUB
  • 111 Views
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Article
Multi-Window CT Based Radiological Traits for Improving Early Detection in Lung Cancer Screening
Hong Lu, Jongphil Kim, Jin Qi, Qian Li, Ying Liu, Matthew B Schabath, Zhaoxiang Ye, Robert J Gillies & Yoganand Balagurunathan
Pages: 12225-12238
Published online: 27 Nov 2020
AbstractforMulti-Window CT Based Radiological Traits for Improving Early Detection in Lung Cancer Screening | Full Text | References | PDF (2.2 MB) | EPUB
  • 73 Views
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Review

Review Article
Cytotoxic Chemotherapy as an Alternative for Systemic Treatment of Advanced Hepatocellular Carcinoma in Developing Countries
Khaled Abouelezz, Dipen Khanapara, Gaber El-Saber Batiha, Esraa A Ahmed & Helal F Hetta
Pages: 12239-12248
Published online: 27 Nov 2020
AbstractforCytotoxic Chemotherapy as an Alternative for Systemic Treatment of Advanced Hepatocellular Carcinoma in Developing Countries | Full Text | References | PDF (535.9 KB) | EPUB
  • 74 Views
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Original Research

Article
Prediction of Lymph Node Metastasis in Superficial Esophageal Cancer Using a Pattern Recognition Neural Network
Han Chen, Xiaoying Zhou, Xinyu Tang, Shuo Li & Guoxin Zhang
Pages: 12249-12258
Published online: 27 Nov 2020
AbstractforPrediction of Lymph Node Metastasis in Superficial Esophageal Cancer Using a Pattern Recognition Neural Network | Full Text | References | PDF (2.9 MB) | EPUB
  • 94 Views
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Article
Long Non-Coding RNA GAS5 Targeting microRNA-21 to Suppress the Invasion and Epithelial–Mesenchymal Transition of Uveal Melanoma
Ying Qi, Qingqing Cui, Wenjing Zhang, Renjie Yao, Dong Xu & Fengyan Zhang
Pages: 12259-12267
Published online: 27 Nov 2020
AbstractforLong Non-Coding RNA GAS5 Targeting microRNA-21 to Suppress the Invasion and Epithelial–Mesenchymal Transition of Uveal Melanoma | Full Text | References | PDF (5.1 MB) | EPUB
  • 74 Views
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Article
Differential Impact of Systemic Lymphadenectomy Upon the Survival of Patients with Type I vs Type II Endometrial Cancer: A Retrospective Observational Cohort Study
Jie Xu, Can Chen, Jing Xiong & Hua Linghu
Pages: 12269-12276
Published online: 30 Nov 2020
AbstractforDifferential Impact of Systemic Lymphadenectomy Upon the Survival of Patients with Type I vs Type II Endometrial Cancer: A Retrospective Observational Cohort Study | Full Text | References | PDF (1.6 MB) | EPUB
  • 55 Views
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Article
Clinical Outcomes and Safety of Different Treatment Modes for Local Recurrence of Rectal Cancer
Zhongzhu Tang, Luying Liu, Dong Liu, Lie Wu, Ke Lu, Ning Zhou, Jinwen Shen, Guiping Chen & Guan Liu
Pages: 12277-12286
Published online: 30 Nov 2020
AbstractforClinical Outcomes and Safety of Different Treatment Modes for Local Recurrence of Rectal Cancer | Full Text | References | PDF (2.1 MB) | EPUB
  • 60 Views
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Article
Impact of Low-Dose rATG Prior to Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Hematologic Malignancies: Reduced Risk of Chronic Graft-versus-Host Disease and Improved Survival Outcomes
Zheng-Yang Song, Han-Yun Ren, Yu-Jun Dong, Yuan Li, Yue Yin, Yu-Hua Sun, Qian Wang, Wei-Lin Xu, Wei Liu, Jin-Ping Ou & Ze-Yin Liang
Pages: 12287-12300
Published online: 30 Nov 2020
AbstractforImpact of Low-Dose rATG Prior to Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Hematologic Malignancies: Reduced Risk of Chronic Graft-versus-Host Disease and Improved Survival Outcomes | Full Text | References | PDF (2.8 MB) | EPUB
  • 69 Views
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Article
Thirty-Day Mortality After Curative and Palliative Anti-Cancer Treatment: Data Interpretation and Lessons for Clinical Implementation
Emad Tashkandi, Bassam Basulaiman, Waleed Alghareeb, Faris Hamadi, Anas Alghamdi, Faez Albabakri, Redhwan Alshabi, Mohammad Jaffal, Abdulrahman Albaradie & Ruqayya Azher
Pages: 12301-12308
Published online: 01 Dec 2020
AbstractforThirty-Day Mortality After Curative and Palliative Anti-Cancer Treatment: Data Interpretation and Lessons for Clinical Implementation | Full Text | References | PDF (278 KB) | EPUB
  • 86 Views
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Article
Long-Term Results of Concurrent Chemoradiotherapy Combined with Anti-EGFR Monoclonal Antibody Prior to Surgery in Locally Advanced Cervical Cancer: A Single-Institute Prospective Study
Defeng Qing, Yuying Wu, Xu Liu, Hailan Jiang, Chaohua Zhu, Pei Liu, Junming Dang, Xianglong Li, Zhaohong Chen, Xianfeng Long, Qiang Pang, Luxing Peng, Shan Deng, Junzhao Gu, Renfeng Zhao, Changyi Chen & Heming Lu
Pages: 12309-12317
Published online: 01 Dec 2020
AbstractforLong-Term Results of Concurrent Chemoradiotherapy Combined with Anti-EGFR Monoclonal Antibody Prior to Surgery in Locally Advanced Cervical Cancer: A Single-Institute Prospective Study | Full Text | References | PDF (1.5 MB) | EPUB
  • 96 Views
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Article
The Outcome of Unscreened Population in Colorectal Cancer: The Impact of Sex and Other Determinants on Cancer Stage
Mesnad Alyabsi, Fouad Sabatin & Abdul Rahman Jazieh
Pages: 12319-12327
Published online: 01 Dec 2020
AbstractforThe Outcome of Unscreened Population in Colorectal Cancer: The Impact of Sex and Other Determinants on Cancer Stage | Full Text | References | PDF (311 KB) | EPUB
  • 173 Views
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Article
Inflammatory Marker Predicts Outcome of Oral Squamous Cell Carcinoma Receiving Chemo-Radiotherapy
Wei Sun, Meng Gao, Guangyuan Hu & Xun Yuan
Pages: 12329-12335
Published online: 01 Dec 2020
AbstractforInflammatory Marker Predicts Outcome of Oral Squamous Cell Carcinoma Receiving Chemo-Radiotherapy | Full Text | References | PDF (755.4 KB) | EPUB
  • 71 Views
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Article
Identification by Comprehensive Bioinformatics Analysis of KIF15 as a Candidate Risk Gene for Triple-Negative Breast Cancer
Jiayu Sheng, Chunyang Li, Mengting Dong & Ke Jiang
Pages: 12337-12348
Published online: 01 Dec 2020
AbstractforIdentification by Comprehensive Bioinformatics Analysis of KIF15 as a Candidate Risk Gene for Triple-Negative Breast Cancer | Full Text | References | PDF (7.1 MB) | EPUB
  • 83 Views
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Article
Prognostic and Predictive Value of a 15 Transcription Factors (TFs) Panel for Hepatocellular Carcinoma
Tian-Hao Zhou, Jing-Zhi Su, Rui Qin, Xi Chen, Gao-Da Ju & Sen Miao
Pages: 12349-12361
Published online: 01 Dec 2020
AbstractforPrognostic and Predictive Value of a 15 Transcription Factors (TFs) Panel for Hepatocellular Carcinoma | Full Text | References | PDF (13 MB) | EPUB
  • 79 Views
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Article
Preoperative Albumin-Bilirubin Grade as a Prognostic Predictor in Colorectal Cancer Patients Who Undergo Radical Resection
Ce Zhu, Xiang Wang, Xinxin Yang, Jing Sun, Bujian Pan, Weiteng Zhang, Xiaodong Chen & Xian Shen
Pages: 12363-12374
Published online: 01 Dec 2020
AbstractforPreoperative Albumin-Bilirubin Grade as a Prognostic Predictor in Colorectal Cancer Patients Who Undergo Radical Resection | Full Text | References | PDF (3 MB) | EPUB
  • 60 Views
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Article
MicroRNA-361-3p Inhibit the Progression of Lymphoma by the Wnt/β-Catenin Signaling Pathway
Hui Zhou, Huifeng Tang, Ning Li, Hang Chen, Xiaohui Chen, Lei Gu, Liang Zhang, Guoyan Tian & Diehong Tao
Pages: 12375-12384
Published online: 02 Dec 2020
AbstractforMicroRNA-361-3p Inhibit the Progression of Lymphoma by the Wnt/β-Catenin Signaling Pathway | Full Text | References | PDF (5.4 MB) | EPUB
  • 77 Views
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Review

Review Article
Multidrug Resistance of Gastric Cancer: The Mechanisms and Chinese Medicine Reversal Agents
Wen-Jie Huang, Shuai Ruan, Fang Wen, Xiao-na Lu, Su-ping Gu, Xiao-xue Chen, Miao Liu & Peng Shu
Pages: 12385-12394
Published online: 02 Dec 2020
AbstractforMultidrug Resistance of Gastric Cancer: The Mechanisms and Chinese Medicine Reversal Agents | Full Text | References | PDF (824.4 KB) | EPUB
  • 225 Views
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Original Research

Article
Multimodal Therapy is a Better Choice for Patients with Brain Metastasis from Cervical Cancer
Shuai Sun, Xin Lian, Xiaoliang Liu, Jiabin Ma, Xiaorong Hou, Fuquan Zhang & Ke Hu
Pages: 12395-12402
Published online: 02 Dec 2020
AbstractforMultimodal Therapy is a Better Choice for Patients with Brain Metastasis from Cervical Cancer | Full Text | References | PDF (501.2 KB) | EPUB
  • 141 Views
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Article
TMPO-AS1, a Novel E2F1-Regulated lncRNA, Contributes to the Proliferation of Lung Adenocarcinoma Cells via Modulating miR-326/SOX12 Axis
Lin Wei, Yugang Liu, Huijun Zhang, Yuefeng Ma, Zenghui Lu, Zhenning Gu & Chao Ding
Pages: 12403-12414
Published online: 02 Dec 2020
AbstractforTMPO-AS1, a Novel E2F1-Regulated lncRNA, Contributes to the Proliferation of Lung Adenocarcinoma Cells via Modulating miR-326/SOX12 Axis | Full Text | References | PDF (6.5 MB) | EPUB
  • 68 Views
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Article
Knockdown of USP8 Inhibits the Growth of Lung Cancer Cells
Zhenhua Rong, Zongmin Zhu, Shihua Cai & Bingqing Zhang
Pages: 12415-12422
Published online: 28 Jan 2023
AbstractforKnockdown of USP8 Inhibits the Growth of Lung Cancer Cells | Full Text | References | PDF (6.4 MB) | EPUB
  • 107 Views
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Article
Risk Factors That Influence Surgical Decision-Making for Patients with Low-Risk Differentiated Thyroid Cancer with Tumor Diameters of 1–4 cm
Xiangming Wang, Chao Zhang, Akanksha Srivastava, Wenbin Yu, Chuan Liu, Dongmin Wei, Yuncheng Li & Jianming Yang
Pages: 12423-12428
Published online: 02 Dec 2020
AbstractforRisk Factors That Influence Surgical Decision-Making for Patients with Low-Risk Differentiated Thyroid Cancer with Tumor Diameters of 1–4 cm | Full Text | References | PDF (985.9 KB) | EPUB
  • 71 Views
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Article
Prevalence of Abnormal Cervical Lesions and Associated Factors Among Women in Harar, Eastern Ethiopia
Elias Bekele Wakwoya & Kasiye Shiferaw Gemechu
Pages: 12429-12437
Published online: 03 Dec 2020
AbstractforPrevalence of Abnormal Cervical Lesions and Associated Factors Among Women in Harar, Eastern Ethiopia | Full Text | References | PDF (431.8 KB) | EPUB
  • 154 Views
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Article
Comparative Study of Auto Plan and Manual Plan for Nasopharyngeal Carcinoma Intensity-Modulated Radiation Therapy
Xin Xin, Chuandong Cheng, Churong Li, Jie Li, Pei Wang, Gang Yin & Jinyi Lang
Pages: 12439-12445
Published online: 02 Dec 2020
AbstractforComparative Study of Auto Plan and Manual Plan for Nasopharyngeal Carcinoma Intensity-Modulated Radiation Therapy | Full Text | References | PDF (1.2 MB) | EPUB
  • 87 Views
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Article
Survival Analysis of Patients with Inflammatory Breast Cancer in Relation to Clinical and Histopathological Characteristics
Marius Preda, Răzvan Ilina, Ovidiu Potre, Cristina Potre & Octavian Mazilu
Pages: 12447-12455
Published online: 03 Dec 2020
AbstractforSurvival Analysis of Patients with Inflammatory Breast Cancer in Relation to Clinical and Histopathological Characteristics | Full Text | References | PDF (3.5 MB) | EPUB
  • 111 Views
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Article
Overexpression of FAM234B Predicts Poor Prognosis in Patients with Luminal Breast Cancer
Lijuan Lyu, Meng Wang, Yi Zheng, Tian Tian, Yujiao Deng, Peng Xu, Shuai Lin, Si Yang, Linghui Zhou, Qian Hao, Ying Wu, Zhijun Dai & Huafeng Kang
Pages: 12457-12471
Published online: 03 Dec 2020
AbstractforOverexpression of FAM234B Predicts Poor Prognosis in Patients with Luminal Breast Cancer | Full Text | References | PDF (8.9 MB) | EPUB
  • 74 Views
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Article
Effective Inhibition of MYC-Amplified Group 3 Medulloblastoma Through Targeting EIF4A1
Yang Zhao, Tiantian Li, Shuaiwei Tian, Wei Meng, Yi Sui, Jian Yang, Baocheng Wang, Zhuangzhuang Liang, Heng Zhao, Yipeng Han, Yujie Tang, Lei Zhang & Jie Ma
Pages: 12473-12485
Published online: 03 Dec 2020
AbstractforEffective Inhibition of MYC-Amplified Group 3 Medulloblastoma Through Targeting EIF4A1 | Full Text | References | PDF (8.5 MB) | EPUB
  • 93 Views
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Open Access

Clinical Trial Report

Case Report
The Effect of Low and High Vacuum Drainage on the Postoperative Drainage of Breast Cancer: Insights from a Prospective, Non-Inferiority, Randomized Clinical Trial
Wanyi Lin, Yaping Yang, Wenjing Zhong, Qun Lin, Nanyan Rao, Gehao Liang, Yun Ling, Zihao Liu, Qing Luo, Zhenluan Tian & Chang Gong
Pages: 12487-12496
Published online: 03 Dec 2020
AbstractforThe Effect of Low and High Vacuum Drainage on the Postoperative Drainage of Breast Cancer: Insights from a Prospective, Non-Inferiority, Randomized Clinical Trial | Full Text | References | PDF (3 MB) | EPUB
  • 161 Views
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Original Research

Article
Long Non-Coding RNA PITPNA-AS1 Accelerates the Progression of Colorectal Cancer Through miR-129-5p/HMGB1 Axis
Chuanping Yuan & Ling Yang
Pages: 12497-12507
Published online: 03 Dec 2020
AbstractforLong Non-Coding RNA PITPNA-AS1 Accelerates the Progression of Colorectal Cancer Through miR-129-5p/HMGB1 Axis | Full Text | References | PDF (6.3 MB) | EPUB
  • 77 Views
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Article
Targeting of the Alox12-12-HETE in Blast Crisis Chronic Myeloid Leukemia Inhibits Leukemia Stem/Progenitor Cell Function
Si Gao, Jialin Hu & Yong Li
Pages: 12509-12517
Published online: 03 Dec 2020
AbstractforTargeting of the Alox12-12-HETE in Blast Crisis Chronic Myeloid Leukemia Inhibits Leukemia Stem/Progenitor Cell Function | Full Text | References | PDF (2.5 MB) | EPUB
  • 78 Views
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Article
Effects of Annona muricata Extract on Triple-Negative Breast Cancer Cells Mediated Through EGFR Signaling
Heba K Alshaeri, Moudi M Alasmari, Zuhair S Natto & Alejandro Pino-Figueroa
Pages: 12519-12526
Published online: 04 Dec 2020
AbstractforEffects of Annona muricata Extract on Triple-Negative Breast Cancer Cells Mediated Through EGFR Signaling | Full Text | References | PDF (2.4 MB) | EPUB
  • 185 Views
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Article
CircRNA_102272 Promotes Cisplatin-Resistance in Hepatocellular Carcinoma by Decreasing MiR-326 Targeting of RUNX2
Yonghai Guan, Ying Zhang, Lina Hao & Zhenwang Nie
Pages: 12527-12534
Published online: 07 Dec 2020
AbstractforCircRNA_102272 Promotes Cisplatin-Resistance in Hepatocellular Carcinoma by Decreasing MiR-326 Targeting of RUNX2 | Full Text | References | PDF (4.5 MB) | EPUB
  • 70 Views
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Letter

Letter
Regarding: “The Association Between Smartphone Use and Breast Cancer Risk Among Taiwanese Women: A Case-Control Study” [Letter]
Seyed Mohammad Javad Mortazavi, Samaneh Abbasi & Seyed Alireza Mortazavi
Pages: 12535-12536
Published online: 07 Dec 2020
CitationforRegarding: “The Association Between Smartphone Use and Breast Cancer Risk Among Taiwanese Women: A Case-Control Study” [Letter] | Full Text | References | PDF (217.3 KB) | EPUB
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Original Research

Article
Preoperative Combined Prediction Models Have Superior Capability in Predicting Survival as the Child-Pugh Grade in Patients with HCC after Interventional Embolotherapy
Meng Qing Xu, Jin Jin Dai, Zhi Sheng Jiang, Fang Xu, Long Wang, Wen Jie Zhang & Zhi Guo Guo
Pages: 12537-12547
Published online: 07 Dec 2020
AbstractforPreoperative Combined Prediction Models Have Superior Capability in Predicting Survival as the Child-Pugh Grade in Patients with HCC after Interventional Embolotherapy | Full Text | References | PDF (1.9 MB) | EPUB
  • 58 Views
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Article
Tumor Differentiation and EGFR Mutation Associated with Disease-Free Survival in Stage IA Lung Adenocarcinoma Patients with Curative Surgery
Lu Yang, Chong Pang, Fei Xu, Guangjian Yang, Haiyan Xu, Changli Wang & Yan Wang
Pages: 12549-12556
Published online: 07 Dec 2020
AbstractforTumor Differentiation and EGFR Mutation Associated with Disease-Free Survival in Stage IA Lung Adenocarcinoma Patients with Curative Surgery | Full Text | References | PDF (2.4 MB) | EPUB
  • 66 Views
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Article
MFAP2 is a Potential Diagnostic and Prognostic Biomarker That Correlates with the Progression of Papillary Thyroid Cancer
Si Yang Dong, Hao Chen, Li Zhi Lin, Lingli Jin, Dan Xiang Chen, Ou Chen Wang & Zhi Qiang Ye
Pages: 12557-12567
Published online: 07 Dec 2020
AbstractforMFAP2 is a Potential Diagnostic and Prognostic Biomarker That Correlates with the Progression of Papillary Thyroid Cancer | Full Text | References | PDF (5.4 MB) | EPUB
  • 62 Views
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Article
Stereotactic Radiosurgery of Brain Metastasis in Patients with a Poor Prognosis: Effective or Overtreatment?
Maciej Harat, Maciej Blok, Izabela Miechowicz & Joanna Kowalewska
Pages: 12569-12579
Published online: 07 Dec 2020
AbstractforStereotactic Radiosurgery of Brain Metastasis in Patients with a Poor Prognosis: Effective or Overtreatment? | Full Text | References | PDF (1.8 MB) | EPUB
  • 56 Views
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Retraction

Retraction
miR-489-3p Inhibits Prostate Cancer Progression by Targeting DLX1 [Retraction]
Page: 12581
Published online: 07 Dec 2020
CitationformiR-489-3p Inhibits Prostate Cancer Progression by Targeting DLX1 [Retraction] | Full Text | PDF (165.2 KB) | EPUB
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Original Research

Article
Prevalence and Genotype Distribution of High-Risk Human Papillomavirus Infection in Women with Abnormal Cervical Cytology: A Population-Based Study in Shanxi Province, China
Li Song, Yuanjing Lyu, Ling Ding, Xiaoxue Li, Wen Gao, Ming Wang, Min Hao, Zhilian Wang & Jintao Wang
Pages: 12583-12591
Published online: 08 Dec 2020
AbstractforPrevalence and Genotype Distribution of High-Risk Human Papillomavirus Infection in Women with Abnormal Cervical Cytology: A Population-Based Study in Shanxi Province, China | Full Text | References | PDF (1.5 MB) | EPUB
  • 121 Views
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Review

Review Article
Osimertinib for Front-Line Treatment of Locally Advanced or Metastatic EGFR-Mutant NSCLC Patients: Efficacy, Acquired Resistance and Perspectives for Subsequent Treatments
Marc G Denis & Jaafar Bennouna
Pages: 12593-12602
Published online: 08 Dec 2020
AbstractforOsimertinib for Front-Line Treatment of Locally Advanced or Metastatic EGFR-Mutant NSCLC Patients: Efficacy, Acquired Resistance and Perspectives for Subsequent Treatments | Full Text | References | PDF (462.7 KB) | EPUB
  • 102 Views
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Original Research

Article
LncRNA NLIPMT Inhibits Tumorigenesis in Esophageal Squamous-Cell Carcinomas by Regulating miR-320/Survivin Axis
Demao Li, Deshang Li, Linglei Meng, Juliang Liu, Chaokang Huang & Huijie Sun
Pages: 12603-12612
Published online: 08 Dec 2020
AbstractforLncRNA NLIPMT Inhibits Tumorigenesis in Esophageal Squamous-Cell Carcinomas by Regulating miR-320/Survivin Axis | Full Text | References | PDF (4.4 MB) | EPUB
  • 56 Views
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Article
Long Non-Coding RNA AC118344.1 Promotes Gastric Cancer Cell Proliferation, Invasion, and Metastasis via AKT2 and Its Downstream Molecules HK2 and MMP2
Lixia Cai, Yangji Xue, Jianzu Ding & Bin Zheng
Pages: 12613-12621
Published online: 08 Dec 2020
AbstractforLong Non-Coding RNA AC118344.1 Promotes Gastric Cancer Cell Proliferation, Invasion, and Metastasis via AKT2 and Its Downstream Molecules HK2 and MMP2 | Full Text | References | PDF (5.7 MB) | EPUB
  • 59 Views
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Article
miR-613 Suppresses Chemoresistance and Stemness in Triple-Negative Breast Cancer by Targeting FAM83A
Cuiping Liu, Yizhou Jiang & Baosan Han
Pages: 12623-12633
Published online: 08 Dec 2020
AbstractformiR-613 Suppresses Chemoresistance and Stemness in Triple-Negative Breast Cancer by Targeting FAM83A | Full Text | References | PDF (7.4 MB) | EPUB
  • 78 Views
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Article
Researches on the Correlation Between Estrogen and Progesterone Receptors Expression and Disease-Free Survival of Endometrial Cancer
Siling Ren, Jingxian Wu, Wanchun Yin, Qianqian Liao, Sailan Gong, Beibei Xuan & Xiaoling Mu
Pages: 12635-12647
Published online: 09 Dec 2020
AbstractforResearches on the Correlation Between Estrogen and Progesterone Receptors Expression and Disease-Free Survival of Endometrial Cancer | Full Text | References | PDF (3.8 MB) | EPUB
  • 132 Views
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Review

Review Article
Relationship of Adherence to Cervical Cancer Treatment Guideline Towards Patients’ Five-year Survival: Systematic Review of Follow-up Trials
Novianti Qurnia Putri, Tiara Bunga Mayang Permata, Ni Ayu Wulandari, Handoko, Endang Nuryadi, Gatot Purwoto & Soehartati Argadikoesoema Gondhowiardjo
Pages: 12649-12655
Published online: 09 Dec 2020
AbstractforRelationship of Adherence to Cervical Cancer Treatment Guideline Towards Patients’ Five-year Survival: Systematic Review of Follow-up Trials | Full Text | References | PDF (2.6 MB) | EPUB
  • 171 Views
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Original Research

Article
Efficacy and Safety of Nab-Paclitaxel Plus S-1 versus Nab-Paclitaxel Plus Gemcitabine for First-Line Chemotherapy in Advanced Pancreatic Ductal Adenocarcinoma
Yuan Zong, Zhi Peng, Xicheng Wang, Ming Lu, Lin Shen & Jun Zhou
Pages: 12657-12666
Published online: 09 Dec 2020
AbstractforEfficacy and Safety of Nab-Paclitaxel Plus S-1 versus Nab-Paclitaxel Plus Gemcitabine for First-Line Chemotherapy in Advanced Pancreatic Ductal Adenocarcinoma | Full Text | References | PDF (2 MB) | EPUB
  • 98 Views
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Article
Quantitative Tyrosine Phosphoproteomic Analysis of Resistance to Radiotherapy in Nasopharyngeal Carcinoma Cells
Lin Shen, Zhanzhan Li & Liangfang Shen
Pages: 12667-12678
Published online: 09 Dec 2020
AbstractforQuantitative Tyrosine Phosphoproteomic Analysis of Resistance to Radiotherapy in Nasopharyngeal Carcinoma Cells | Full Text | References | PDF (2 MB) | EPUB
  • 75 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA KCNMB2-AS1 Increases ROCK1 Expression by Sponging microRNA-374a-3p to Facilitate the Progression of Non–Small-Cell Lung Cancer
Haitao Yang, Ziyi Wang & Zhenyuan Wang
Pages: 12679-12695
Published online: 11 Dec 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA KCNMB2-AS1 Increases ROCK1 Expression by Sponging microRNA-374a-3p to Facilitate the Progression of Non–Small-Cell Lung Cancer | PDF (14.7 MB)
  • 16 Views
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Article
RETRACTED ARTICLE: Long Noncoding RNA LINC01426 Sequesters microRNA-519d-5p to Promote Non-Small Cell Lung Cancer Progression by Increasing ETS1 Expression
Jixin Dai, Bing Wang, Yueming Zhao, Xuerong Zuo, Hongxia Cui, Xi Chen & Xianhong Liu
Pages: 12697-12708
Published online: 10 Dec 2020
AbstractforRETRACTED ARTICLE: Long Noncoding RNA LINC01426 Sequesters microRNA-519d-5p to Promote Non-Small Cell Lung Cancer Progression by Increasing ETS1 Expression | PDF (8 MB)
  • 20 Views
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Article
Anlotinib Plus S-1 for Patients with EGFR Mutation-Negative Advanced Squamous Cell Lung Cancer with PS Scores of 2–3 After Progression of Second-Line or Later-Line Treatment
Xiao-Hong Xie, Fei Wang, Xin-Qing Lin, Yin-Yin Qin, Zhan-Hong Xie, Jie-Xia Zhang, Ming Ouyang & Cheng-Zhi Zhou
Pages: 12709-12714
Published online: 10 Dec 2020
AbstractforAnlotinib Plus S-1 for Patients with EGFR Mutation-Negative Advanced Squamous Cell Lung Cancer with PS Scores of 2–3 After Progression of Second-Line or Later-Line Treatment | Full Text | References | PDF (930.7 KB) | EPUB
  • 62 Views
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Article
Association Between the HER2 Protein Expression Level and the Efficacy of Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer
Hui Yan, Hui Xiao, Jiujun Zhu, Jingyang Zhang & Zhenzhen Liu
Pages: 12715-12722
Published online: 10 Dec 2020
AbstractforAssociation Between the HER2 Protein Expression Level and the Efficacy of Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer | Full Text | References | PDF (369.5 KB) | EPUB
  • 75 Views
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Article
MiR-139-5p-ZEB1 is a Molecular Regulator of Growth, Invasion, and Epithelial-to-Mesenchymal Transition of Cervical Cancer
Jinrui Sun, Shanshan Wang, Ping Liu & Yulan Liu
Pages: 12723-12733
Published online: 10 Dec 2020
AbstractforMiR-139-5p-ZEB1 is a Molecular Regulator of Growth, Invasion, and Epithelial-to-Mesenchymal Transition of Cervical Cancer | Full Text | References | PDF (7 MB) | EPUB
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Review

Review Article
Regulatory Roles of Tumor Necrosis Factor-α-Induced Protein 8 Like-Protein 2 in Inflammation, Immunity and Cancers: A Review
Zhengzhong Gu, Xiaohan Cui, Pengda Sun & Xudong Wang
Pages: 12735-12746
Published online: 14 Dec 2020
AbstractforRegulatory Roles of Tumor Necrosis Factor-α-Induced Protein 8 Like-Protein 2 in Inflammation, Immunity and Cancers: A Review | Full Text | References | PDF (999.9 KB) | EPUB
  • 103 Views
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Original Research

Article
α-E-Catenin (CTNNA1) Inhibits Cell Proliferation, Invasion and EMT of Bladder Cancer
Qiang Chi, Hui Xu, Dianbin Song, Zhiyong Wang, Zemin Wang & Guang Ma
Pages: 12747-12758
Published online: 14 Dec 2020
Abstractforα-E-Catenin (CTNNA1) Inhibits Cell Proliferation, Invasion and EMT of Bladder Cancer | Full Text | References | PDF (6.3 MB) | EPUB
  • 109 Views
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Article
METTL14 Overexpression Promotes Osteosarcoma Cell Apoptosis and Slows Tumor Progression via Caspase 3 Activation
Ziwen Liu, Ning Liu, Zhipeng Huang & Wenbo Wang
Pages: 12759-12767
Published online: 11 Dec 2020
AbstractforMETTL14 Overexpression Promotes Osteosarcoma Cell Apoptosis and Slows Tumor Progression via Caspase 3 Activation | Full Text | References | PDF (4.6 MB) | EPUB
  • 90 Views
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Article
RETRACTED ARTICLE: Kinesin Superfamily Member 18B (KIF18B) Promotes Cell Proliferation in Colon Adenocarcinoma
Fei Zhao, Yunzhang Feng, Xueqiang Zhang, Xiaohui Liu & Aili Li
Pages: 12769-12778
Published online: 11 Dec 2020
AbstractforRETRACTED ARTICLE: Kinesin Superfamily Member 18B (KIF18B) Promotes Cell Proliferation in Colon Adenocarcinoma | PDF (3.8 MB)
  • 42 Views
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Article
Hsa_circ_0046263 Drives the Carcinogenesis and Metastasis of Non-Small Cell Lung Cancer Through the Promotion of NOVA2 by Absorbing Mir-940 as a Molecular Sponge
Guanghui Li, Chunsheng Zhao, Haining Zhang, Jia Yu, Yang Sun & Yingying Zhang
Pages: 12779-12790
Published online: 14 Dec 2020
AbstractforHsa_circ_0046263 Drives the Carcinogenesis and Metastasis of Non-Small Cell Lung Cancer Through the Promotion of NOVA2 by Absorbing Mir-940 as a Molecular Sponge | Full Text | References | PDF (7.5 MB) | EPUB
  • 61 Views
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Article
Lymphovascular Invasion as a Prognostic Factor in Non-Metastatic Adenocarcinoma of Esophagogastric Junction After Radical Surgery
Chengbin Zheng, Xingyu Feng, Jiabin Zheng, Qian Yan, Xu Hu, Huolun Feng, Zhenru Deng, Qianchao Liao, Junjiang Wang & Yong Li
Pages: 12791-12799
Published online: 14 Dec 2020
AbstractforLymphovascular Invasion as a Prognostic Factor in Non-Metastatic Adenocarcinoma of Esophagogastric Junction After Radical Surgery | Full Text | References | PDF (3.5 MB) | EPUB
  • 84 Views
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Article
The Extent of Therapeutic Central Compartment Neck Dissection in Unilateral cT1N1a or cT2N1a Papillary Thyroid Carcinoma
Nan Liu, Yupeng Yang, Bo Chen, Luchuan Li, Qingdong Zeng, Lei Sheng, Bin Zhang, Weili Liang & Bin Lv
Pages: 12801-12809
Published online: 14 Dec 2020
AbstractforThe Extent of Therapeutic Central Compartment Neck Dissection in Unilateral cT1N1a or cT2N1a Papillary Thyroid Carcinoma | Full Text | References | PDF (2 MB) | EPUB
  • 99 Views
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Article
The Significance of Platelet–Albumin–Bilirubin (PALBI) Grade in Hepatocellular Carcinoma Patients Stratified According to Platelet Count
Qing Pang, Shuangchi Liu, Luyao Wang, Huadong Pan, Chunfang Wang, Lei Zhou, Yimin Lu & Huichun Liu
Pages: 12811-12822
Published online: 14 Dec 2020
AbstractforThe Significance of Platelet–Albumin–Bilirubin (PALBI) Grade in Hepatocellular Carcinoma Patients Stratified According to Platelet Count | Full Text | References | PDF (6.7 MB) | EPUB
  • 97 Views
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Review

Review Article
Progress of Artificial Intelligence in Gynecological Malignant Tumors
Jie Zhou, Zhi Ying Zeng & Li Li
Pages: 12823-12840
Published online: 14 Dec 2020
AbstractforProgress of Artificial Intelligence in Gynecological Malignant Tumors | Full Text | References | PDF (3.9 MB) | EPUB
  • 338 Views
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Original Research

Article
LCN2 Mediated by IL-17 Affects the Proliferation, Migration, Invasion and Cell Cycle of Gastric Cancer Cells by Targeting SLPI
Jing Xu, ShengXiang Lv, Wei Meng & Fang Zuo
Pages: 12841-12849
Published online: 14 Dec 2020
AbstractforLCN2 Mediated by IL-17 Affects the Proliferation, Migration, Invasion and Cell Cycle of Gastric Cancer Cells by Targeting SLPI | Full Text | References | PDF (7.3 MB) | EPUB
  • 99 Views
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Corrigendum

Correction
Comparative Study of Auto Plan and Manual Plan for Nasopharyngeal Carcinoma Intensity-Modulated Radiation Therapy [Corrigendum]
Page: 12851
Published online: 15 Dec 2020
CitationforComparative Study of Auto Plan and Manual Plan for Nasopharyngeal Carcinoma Intensity-Modulated Radiation Therapy [Corrigendum] | Full Text | PDF (159.8 KB) | EPUB
  • 63 Views
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Original Research

Article
Circ-PRKDC Facilitates the Progression of Colorectal Cancer Through miR-198/DDR1 Regulatory Axis
Guixiang Wang, Yajun Li, Hufei Zhu, Guoqiang Huo, Jingying Bai & Zhiyong Gao
Pages: 12853-12865
Published online: 15 Dec 2020
AbstractforCirc-PRKDC Facilitates the Progression of Colorectal Cancer Through miR-198/DDR1 Regulatory Axis | Full Text | References | PDF (8.1 MB) | EPUB
  • 83 Views
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Article
Long Noncoding RNA SNHG22 Induces Cell Migration, Invasion, and Angiogenesis of Gastric Cancer Cells via microRNA-361-3p/HMGA1/Wnt/β-Catenin Axis
Xiaofeng Cui, Huaiyu Zhang, Tong Chen, Wei Yu & Kexin Shen
Pages: 12867-12883
Published online: 15 Dec 2020
AbstractforLong Noncoding RNA SNHG22 Induces Cell Migration, Invasion, and Angiogenesis of Gastric Cancer Cells via microRNA-361-3p/HMGA1/Wnt/β-Catenin Axis | Full Text | References | PDF (14 MB) | EPUB
  • 100 Views
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Article
Immunoscore Signature Predicts Postoperative Survival and Adjuvant Chemotherapeutic Benefits in Esophageal Squamous Cell Carcinoma
Lingdun Zhuge, Binhao Huang, Juntao Xie, Zhendong Gao, Difan Zheng, Shanbo Zheng, Jiaqing Xiang & Jie Zhang
Pages: 12885-12894
Published online: 15 Dec 2020
AbstractforImmunoscore Signature Predicts Postoperative Survival and Adjuvant Chemotherapeutic Benefits in Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (4.5 MB) | EPUB
  • 63 Views
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Article
Expression and Importance of TMED2 in Multiple Myeloma Cells
Xueling Ge, Wei Jiang, Yujie Jiang, Xiao Lv, Xin Liu & Xin Wang
Pages: 12895-12903
Published online: 16 Dec 2020
AbstractforExpression and Importance of TMED2 in Multiple Myeloma Cells | Full Text | References | PDF (4.9 MB) | EPUB
  • 76 Views
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Article
Cost-Effectiveness of Ribociclib for Hormone Receptor-Positive HER2-Negative Advanced Breast Cancer
Jiangping Yang, Jiaqi Han, Maolang Tian, Kun Tian, Wenjun Liao & Xi Yan
Pages: 12905-12913
Published online: 15 Dec 2020
AbstractforCost-Effectiveness of Ribociclib for Hormone Receptor-Positive HER2-Negative Advanced Breast Cancer | Full Text | References | PDF (2.2 MB) | EPUB
  • 147 Views
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Corrigendum

Correction
Integrative Gene Expression Profiling Reveals That Dysregulated Triple microRNAs Confer Paclitaxel Resistance in Non-Small Cell Lung Cancer via Cotargeting MAPT [Corrigendum]
Pages: 12915-12916
Published online: 16 Dec 2020
CitationforIntegrative Gene Expression Profiling Reveals That Dysregulated Triple microRNAs Confer Paclitaxel Resistance in Non-Small Cell Lung Cancer via Cotargeting MAPT [Corrigendum] | Full Text | PDF (1.1 MB) | EPUB
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Erratum

Correction
Surgical Outcomes of Transvaginal Neobladder-Vaginal Fistula Repair After Radical Cystectomy with Ileal Orthotopic Neobladder: A Case–Control Study [Erratum]
Page: 12917
Published online: 17 Dec 2020
CitationforSurgical Outcomes of Transvaginal Neobladder-Vaginal Fistula Repair After Radical Cystectomy with Ileal Orthotopic Neobladder: A Case–Control Study [Erratum] | Full Text | PDF (160.4 KB) | EPUB
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Original Research

Article
Cost-Effectiveness Analysis of Maintenance Olaparib in Patients with Metastatic Pancreatic Cancer and a Germline BRCA1/2 Mutation Based on the POLO Trial
Mei Zhan, Hanrui Zheng, Yu Yang, Zhiyao He, Ting Xu & Qiu Li
Pages: 12919-12926
Published online: 16 Dec 2020
AbstractforCost-Effectiveness Analysis of Maintenance Olaparib in Patients with Metastatic Pancreatic Cancer and a Germline BRCA1/2 Mutation Based on the POLO Trial | Full Text | References | PDF (2.7 MB) | EPUB
  • 100 Views
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Review

Review Article
How Can Alternative Exercise Traditions Help Against the Background of the COVID-19 in Cancer Care? An Overview of Systematic Reviews
Yang Zhang, Fang Yao, Xiaohong Kuang, Lijuan Li, Lihua Huang, Qi Zhou, Jiazhu Peng & Qingyu Chang
Pages: 12927-12944
Published online: 17 Dec 2020
AbstractforHow Can Alternative Exercise Traditions Help Against the Background of the COVID-19 in Cancer Care? An Overview of Systematic Reviews | Full Text | References | PDF (936.6 KB) | EPUB
  • 84 Views
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Original Research

Article
CircPVT1 Regulates Cell Proliferation, Apoptosis and Glycolysis in Hepatocellular Carcinoma via miR-377/TRIM23 Axis
Nan Bu, Zheng Dong, Lingfeng Zhang, Weibo Zhu, Furong Wei & Sheng Zheng
Pages: 12945-12956
Published online: 16 Dec 2020
AbstractforCircPVT1 Regulates Cell Proliferation, Apoptosis and Glycolysis in Hepatocellular Carcinoma via miR-377/TRIM23 Axis | Full Text | References | PDF (7.6 MB) | EPUB
  • 94 Views
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Article
Survival Analysis of Antineoplastic Treatment for Older Patients with Metastatic Non-Small-Cell Lung Cancer: A Clinical Database Study
Chin-Hsiu Yu, Ya-Ai Cheng, Ru-Yih Chen, Yu-Lung Wu & Min-Hsi Lin
Pages: 12957-12964
Published online: 16 Dec 2020
AbstractforSurvival Analysis of Antineoplastic Treatment for Older Patients with Metastatic Non-Small-Cell Lung Cancer: A Clinical Database Study | Full Text | References | PDF (433.7 KB) | EPUB
  • 80 Views
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Article
Melanoma-Derived Exosomes Endow Fibroblasts with an Invasive Potential via miR-21 Target Signaling Pathway
Chenmeiyi Wang, Yiting Wang, Xiulin Chang, Xiaoyun Ba, Na Hu, Qing Liu, Liaoqiong Fang & Zhibiao Wang
Pages: 12965-12974
Published online: 16 Dec 2020
AbstractforMelanoma-Derived Exosomes Endow Fibroblasts with an Invasive Potential via miR-21 Target Signaling Pathway | Full Text | References | PDF (4.2 MB) | EPUB
  • 85 Views
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Article
Bronchial Sleeve Resection with Complete Pulmonary Preservation: A Single-Center Experience
Jiangnan Duan, Haomin Cai, Wei Huang, Lin Lin, Liang Wu & Jiang Fan
Pages: 12975-12982
Published online: 16 Dec 2020
AbstractforBronchial Sleeve Resection with Complete Pulmonary Preservation: A Single-Center Experience | Full Text | References | PDF (720.7 KB) | EPUB
  • 85 Views
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Article
Long Non-Coding RNA OIP5-AS1 Contributes to Gallbladder Cancer Cell Invasion and Migration by miR-143-3p Suppression
Jing Li, Hui Zhang & Hongwu Luo
Pages: 12983-12992
Published online: 17 Dec 2020
AbstractforLong Non-Coding RNA OIP5-AS1 Contributes to Gallbladder Cancer Cell Invasion and Migration by miR-143-3p Suppression | Full Text | References | PDF (5.5 MB) | EPUB
  • 67 Views
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Article
Upregulated Histone Deacetylase 6 Associates with Malignant Progression of Melanoma and Predicts the Prognosis of Patients
Zhicheng Hu, Yanchao Rong, Shuting Li, Shanqiang Qu & Shaobin Huang
Pages: 12993-13001
Published online: 17 Dec 2020
AbstractforUpregulated Histone Deacetylase 6 Associates with Malignant Progression of Melanoma and Predicts the Prognosis of Patients | Full Text | References | PDF (2.9 MB) | EPUB
  • 67 Views
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Article
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway
Weixu Luo, Yuanshan Han, Pan Meng, Qin Yang, Hongqing Zhao, Jia Ling & Yuhong Wang
Pages: 13003-13014
Published online: 18 Dec 2020
AbstractforResatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway | Full Text | References | PDF (6.5 MB) | EPUB
  • 161 Views
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Case Report

Case Report
Metastasis of Ovarian Cancer to Breast: A Case Report and Review of Imaging Manifestations
Jing Wang & Baohua Wang
Pages: 13015-13021
Published online: 18 Dec 2020
AbstractforMetastasis of Ovarian Cancer to Breast: A Case Report and Review of Imaging Manifestations | Full Text | References | PDF (509.8 KB) | EPUB
  • 88 Views
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Review

Review Article
Postoperative Radiotherapy for Thoracic Esophageal Carcinoma with Upfront R0 Esophagectomy
Yichun Wang & Fan Wang
Pages: 13023-13032
Published online: 18 Dec 2020
AbstractforPostoperative Radiotherapy for Thoracic Esophageal Carcinoma with Upfront R0 Esophagectomy | Full Text | References | PDF (435.1 KB) | EPUB
  • 75 Views
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Original Research

Article
H19 Rises in Gastric Cancer and Exerts a Tumor-Promoting Function via miR-138/E2F2 Axis
Jingrong Yu, Cheng Fang, Ziyue Zhang, Guifang Zhang, Lihong Shi, Jiayi Qian & Jianping Xiong
Pages: 13033-13042
Published online: 21 Dec 2020
AbstractforH19 Rises in Gastric Cancer and Exerts a Tumor-Promoting Function via miR-138/E2F2 Axis | Full Text | References | PDF (5.7 MB) | EPUB
  • 75 Views
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Article
Long-Term Outcomes of Radical Surgery for Transverse Colon Cancer Staged from I to IIIC
Yaofei Jiang, Zhenhong Zou, Zulei Zhang, Yi Zhang, Yuting Sun & Bo Liang
Pages: 13043-13049
Published online: 22 Dec 2020
AbstractforLong-Term Outcomes of Radical Surgery for Transverse Colon Cancer Staged from I to IIIC | Full Text | References | PDF (329.1 KB) | EPUB
  • 61 Views
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Article
BGN and COL11A1 Regulatory Network Analysis in Colorectal Cancer (CRC) Reveals That BGN Influences CRC Cell Biological Functions and Interacts with miR-6828-5p
Danqi Chen, Ying Qin, Mengmeng Dai, Lulu Li, Hongpeng Liu, Yaoyao Zhou, Cheng Qiu, Yan Chen & Yuyang Jiang
Pages: 13051-13069
Published online: 22 Dec 2020
AbstractforBGN and COL11A1 Regulatory Network Analysis in Colorectal Cancer (CRC) Reveals That BGN Influences CRC Cell Biological Functions and Interacts with miR-6828-5p | Full Text | References | PDF (11.5 MB) | EPUB
  • 145 Views
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Article
RETRACTED ARTICLE: Long Non-Coding RNA LINC00466 Knockdown Inhibits Tongue Squamous Cell Carcinoma Malignancy by Targeting microRNA-493/HMGA2
Chao Hou, Yanli Dong & Bo Du
Pages: 13071-13084
Published online: 22 Dec 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA LINC00466 Knockdown Inhibits Tongue Squamous Cell Carcinoma Malignancy by Targeting microRNA-493/HMGA2 | PDF (8.2 MB)
  • 12 Views
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Article
Cyclin F Downregulation Affects Epithelial-Mesenchymal Transition Increasing Proliferation and Migration of the A-375 Melanoma Cell Line
Adrian Krajewski, Maciej Gagat, Klaudia Mikołajczyk, Magdalena Izdebska, Agnieszka Żuryń & Alina Grzanka
Pages: 13085-13097
Published online: 22 Dec 2020
AbstractforCyclin F Downregulation Affects Epithelial-Mesenchymal Transition Increasing Proliferation and Migration of the A-375 Melanoma Cell Line | Full Text | References | PDF (5.3 MB) | EPUB
  • 77 Views
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Article
Predicting Prostate Cancer Upgrading of Biopsy Gleason Grade Group at Radical Prostatectomy Using Machine Learning-Assisted Decision-Support Models
Hailang Liu, Kun Tang, Ejun Peng, Liang Wang, Ding Xia & Zhiqiang Chen
Pages: 13099-13110
Published online: 22 Dec 2020
AbstractforPredicting Prostate Cancer Upgrading of Biopsy Gleason Grade Group at Radical Prostatectomy Using Machine Learning-Assisted Decision-Support Models | Full Text | References | PDF (3.5 MB) | EPUB
  • 121 Views
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Article
Independent Risk Factors of Early Recurrence After Curative Resection for Perihilar Cholangiocarcinoma: Adjuvant Chemotherapy May Be Beneficial in Early Recurrence Subgroup
Jian Zhao, Wei Zhang, Jun Zhang, Yun-Tian Chen, Wen-Jie Ma, Si-Yun Liu, Fu-Yu Li & Bin Song
Pages: 13111-13123
Published online: 22 Dec 2020
AbstractforIndependent Risk Factors of Early Recurrence After Curative Resection for Perihilar Cholangiocarcinoma: Adjuvant Chemotherapy May Be Beneficial in Early Recurrence Subgroup | Full Text | References | PDF (3.3 MB) | EPUB
  • 67 Views
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Article
The Significance of Neutrophil-to-Lymphocyte Ratio and Combined Chemoradiotherapy in Patients Undergoing Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer
Chun-Te Wu, Yun-Ching Huang, Wen-Cheng Chen & Miao-Fen Chen
Pages: 13125-13135
Published online: 22 Dec 2020
AbstractforThe Significance of Neutrophil-to-Lymphocyte Ratio and Combined Chemoradiotherapy in Patients Undergoing Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer | Full Text | References | PDF (3.9 MB) | EPUB
  • 68 Views
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Article
LncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer Progression
Rui Chen, Shenkang Zhou, Jianhui Chen, Senbin Lin, Feifei Ye & Pinlu Jiang
Pages: 13137-13148
Published online: 22 Dec 2020
AbstractforLncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer Progression | Full Text | References | PDF (7.9 MB) | EPUB
  • 93 Views
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Article
Pyrrolidine Dithiocarbamate Facilitates Arsenic Trioxide Against Pancreatic Cancer via Perturbing Ubiquitin-Proteasome Pathway
Simin Yu, Ning Wu, Jianmin Zhu, Ying Liu & Jinbin Han
Pages: 13149-13159
Published online: 22 Dec 2020
AbstractforPyrrolidine Dithiocarbamate Facilitates Arsenic Trioxide Against Pancreatic Cancer via Perturbing Ubiquitin-Proteasome Pathway | Full Text | References | PDF (5.4 MB) | EPUB
  • 76 Views
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Article
Apolipoprotein E2 Promotes the Migration and Invasion of Pancreatic Cancer Cells via Activation of the ERK1/2 Signaling Pathway
Hui Wang, Shaoxia Du, Jun Cai, Juan Wang & Xiaohong Shen
Pages: 13161-13171
Published online: 22 Dec 2020
AbstractforApolipoprotein E2 Promotes the Migration and Invasion of Pancreatic Cancer Cells via Activation of the ERK1/2 Signaling Pathway | Full Text | References | PDF (9.5 MB) | EPUB
  • 61 Views
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Article
METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner
Yuntao Shi, Yingying Zhuang, Jialing Zhang, Mengxue Chen & Shangnong Wu
Pages: 13173-13184
Published online: 23 Dec 2020
AbstractforMETTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner | Full Text | References | PDF (8.6 MB) | EPUB
  • 190 Views
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Article
A Clinical Analysis of the Diagnosis and Treatment of Fetal Sacrococcygeal Teratomas
Xiu-Qiong Zheng, Jian-Ying Yan, Rong-Li Xu, Xue-Chun Wang, Xian Chen & Ke-Hua Huang
Pages: 13185-13193
Published online: 23 Dec 2020
AbstractforA Clinical Analysis of the Diagnosis and Treatment of Fetal Sacrococcygeal Teratomas | Full Text | References | PDF (590 KB) | EPUB
  • 103 Views
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Article
TRIB3 Promotes Lung Adenocarcinoma Progression via an Enhanced Warburg Effect
Yutong Xing, Peng Luo, Rui Hu, Duanduan Wang, Gang Zhou & Jie Jiang
Pages: 13195-13206
Published online: 23 Dec 2020
AbstractforTRIB3 Promotes Lung Adenocarcinoma Progression via an Enhanced Warburg Effect | Full Text | References | PDF (8.7 MB) | EPUB
  • 88 Views
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Article
The Detection of Plasma Soluble Podoplanin of Patients with Breast Cancer and Its Clinical Signification
Xinyi Zhu, Mengqiao Xu, Xingpeng Zhao, Fei Shen, Changgeng Ruan & Yiming Zhao
Pages: 13207-13214
Published online: 23 Dec 2020
AbstractforThe Detection of Plasma Soluble Podoplanin of Patients with Breast Cancer and Its Clinical Signification | Full Text | References | PDF (2.3 MB) | EPUB
  • 70 Views
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Article
Clinical Value of Ultrasound-Guided Minimally Invasive Biopsy in the Diagnosis or Treatment of Breast Nodules
Yan-Hong Gao, Shi-Cong Zhu, Ya Xu, Shun-Ji Gao, Yu Zhang, Qun-An Huang, Wen-Hong Gao, Jian Zhu, Hui-Juan Xiang & Xu-Hui Gao
Pages: 13215-13222
Published online: 23 Dec 2020
AbstractforClinical Value of Ultrasound-Guided Minimally Invasive Biopsy in the Diagnosis or Treatment of Breast Nodules | Full Text | References | PDF (1.6 MB) | EPUB
  • 82 Views
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Article
FDG PET Predicts the Effects of 131I and Prognosis for Patients with Bone Metastases from Differentiated Thyroid Carcinoma
Danyang Wang, Yongli Bai, Yanlei Huo & Chao Ma
Pages: 13223-13232
Published online: 23 Dec 2020
AbstractforFDG PET Predicts the Effects of 131I and Prognosis for Patients with Bone Metastases from Differentiated Thyroid Carcinoma | Full Text | References | PDF (2.5 MB) | EPUB
  • 62 Views
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Article
PD-L1 in Combination with CD8+TIL and HIF-1α are Promising Prognosis Predictors of Head and Neck Squamous Cell Carcinoma
Zihan Zhou, Dianbin Mu, Dexian Zhang, Xianbin Zhang, Xingchen Ding, Jia Yang, Xinbin Bai & Man Hu
Pages: 13233-13239
Published online: 23 Dec 2020
AbstractforPD-L1 in Combination with CD8+TIL and HIF-1α are Promising Prognosis Predictors of Head and Neck Squamous Cell Carcinoma | Full Text | References | PDF (3.6 MB) | EPUB
  • 71 Views
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Article
KIF14 and KIF23 Promote Cell Proliferation and Chemoresistance in HCC Cells, and Predict Worse Prognosis of Patients with HCC
Chunxia Cheng, Xingxing Wu, Yu Shen & Quanxi Li
Pages: 13241-13257
Published online: 23 Dec 2020
AbstractforKIF14 and KIF23 Promote Cell Proliferation and Chemoresistance in HCC Cells, and Predict Worse Prognosis of Patients with HCC | Full Text | References | PDF (18.1 MB) | EPUB
  • 134 Views
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Review

Review Article
Regulation of Autophagy by Glycolysis in Cancer
Ying Chu, Yi Chang, Wei Lu, Xiumei Sheng, Shengjun Wang, Huaxi Xu & Jie Ma
Pages: 13259-13271
Published online: 23 Dec 2020
AbstractforRegulation of Autophagy by Glycolysis in Cancer | Full Text | References | PDF (2 MB) | EPUB
  • 331 Views
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Original Research

Article
RETRACTED ARTICLE: SHP-2 Interacts with CD81 and Regulates the Malignant Evolution of Colorectal Cancer by Inhibiting Epithelial–Mesenchymal Transition
Huaqin Yuan, Jun Zhao, Yang Yang, Rongfu Wei, Liangxue Zhu, Jie Wang, Meiqing Ding, Mingyun Wang & Yanhong Gu
Pages: 13273-13284
Published online: 23 Dec 2020
AbstractforRETRACTED ARTICLE: SHP-2 Interacts with CD81 and Regulates the Malignant Evolution of Colorectal Cancer by Inhibiting Epithelial–Mesenchymal Transition | PDF (7.5 MB)
  • 355 Views
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Article
RETRACTED ARTICLE: Long Non-Coding RNA ZNF667-AS1 Knockdown Curbs Liver Metastasis in Acute Myeloid Leukemia by Regulating the microRNA-206/AKAP13 Axis
Nan Wang, Yanping Feng, Jinye Xie, Hui Han, Qian Dong & Weijia Wang
Pages: 13285-13300
Published online: 23 Dec 2020
AbstractforRETRACTED ARTICLE: Long Non-Coding RNA ZNF667-AS1 Knockdown Curbs Liver Metastasis in Acute Myeloid Leukemia by Regulating the microRNA-206/AKAP13 Axis | PDF (15.1 MB)
  • 71 Views
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Article
Prognostic Value of Preoperative Fibrinogen for Predicting Clinical Outcome in Patients with Nonmetastatic Colorectal Cancer
Yu Sun, Weiying Han, Yongxi Song, Peng Gao, Yuchong Yang, Dehao Yu, Yu Wang & Zhenning Wang
Pages: 13301-13309
Published online: 23 Dec 2020
AbstractforPrognostic Value of Preoperative Fibrinogen for Predicting Clinical Outcome in Patients with Nonmetastatic Colorectal Cancer | Full Text | References | PDF (2.9 MB) | EPUB
  • 82 Views
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Article
NUCKS1 Promotes Proliferation, Invasion and Migration of Non-Small Cell Lung Cancer by Upregulating CDK1 Expression
Shufen Zhao, Baiyao Wang, Yanning Ma, Junjie Kuang, Jiyun Liang & Yawei Yuan
Pages: 13311-13323
Published online: 24 Dec 2020
AbstractforNUCKS1 Promotes Proliferation, Invasion and Migration of Non-Small Cell Lung Cancer by Upregulating CDK1 Expression | Full Text | References | PDF (13.6 MB) | EPUB
  • 110 Views
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Article
MiR-548d-3p Promotes Gastric Cancer by Targeting RSK4
Hui Liang, Cong Hu, Xu Lin, Zhuocheng He, Zhiwen Lin & Jun Dai
Pages: 13325-13337
Published online: 24 Dec 2020
AbstractforMiR-548d-3p Promotes Gastric Cancer by Targeting RSK4 | Full Text | References | PDF (12.5 MB) | EPUB
  • 77 Views
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Article
Radiotherapy Combined with Chemotherapy for Regional Lymph Node Recurrence in Gastric Cancer
Liang Cai, Ganlu Ouyang, Xin Wang, Zhiping Li & Yali Shen
Pages: 13339-13346
Published online: 24 Dec 2020
AbstractforRadiotherapy Combined with Chemotherapy for Regional Lymph Node Recurrence in Gastric Cancer | Full Text | References | PDF (1.4 MB) | EPUB
  • 64 Views
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Article
RETRACTED ARTICLE: Effects of LncRNA HCP5/miR-214-3p/MAPK1 Molecular Network on Renal Cell Carcinoma Cells
Jun-Feng Hao, Pei Chen, He-Yi Li, Ya-Jing Li & Yu-Ling Zhang
Pages: 13347-13356
Published online: 24 Dec 2020
AbstractforRETRACTED ARTICLE: Effects of LncRNA HCP5/miR-214-3p/MAPK1 Molecular Network on Renal Cell Carcinoma Cells | PDF (8.1 MB)
  • 25 Views
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Article
LncRNA NEAT1/miR-204/NUAK1 Axis is a Potential Therapeutic Target for Non-Small Cell Lung Cancer
Ming-Ming Zhao, Lin-Yang Ge, Liang-Feng Yang, Hai-Xia Zheng, Gang Chen, Li-Zheng Wu, Shao-Ming Shi, Nan Wang & Yan-Ping Hang
Pages: 13357-13368
Published online: 29 Dec 2020
AbstractforLncRNA NEAT1/miR-204/NUAK1 Axis is a Potential Therapeutic Target for Non-Small Cell Lung Cancer | Full Text | References | PDF (9.7 MB) | EPUB
  • 127 Views
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Review

Review Article
Thermal Ablation for Papillary Thyroid Microcarcinoma: How Far We Have Come?
Yu Min, Xing Wang, Hang Chen, Jialin Chen, Ke Xiang & Guobing Yin
Pages: 13369-13379
Published online: 24 Dec 2020
AbstractforThermal Ablation for Papillary Thyroid Microcarcinoma: How Far We Have Come? | Full Text | References | PDF (1.4 MB) | EPUB
  • 132 Views
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Original Research

Article
Comparisons of Therapeutic and Aesthetic Effects of One-Stage Implant-Based Breast Reconstruction with and without Biological Matrix
Peng Gao, Zhongzhao Wang, Xiangyi Kong, Xiangyu Wang, Yi Fang & Jing Wang
Pages: 13381-13392
Published online: 29 Dec 2020
AbstractforComparisons of Therapeutic and Aesthetic Effects of One-Stage Implant-Based Breast Reconstruction with and without Biological Matrix | Full Text | References | PDF (542.2 KB) | EPUB
  • 100 Views
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Article
miR-196b-5p Promotes Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells via Targeting RSPO2
Qian Xu & Zhenwu Xu
Pages: 13393-13402
Published online: 29 Dec 2020
AbstractformiR-196b-5p Promotes Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells via Targeting RSPO2 | Full Text | References | PDF (3.8 MB) | EPUB
  • 67 Views
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Article
LncRNA PVT1 Acts as a Tumor Promoter in Thyroid Cancer and Promotes Tumor Progression by Mediating miR-423-5p-PAK3
Qiu-Yu Lin, Qian-Le Qi, Sen Hou, Zhen Chen, Laney Zhang, Hong-Guang Zhao & Cheng-He Lin
Pages: 13403-13413
Published online: 30 Dec 2020
AbstractforLncRNA PVT1 Acts as a Tumor Promoter in Thyroid Cancer and Promotes Tumor Progression by Mediating miR-423-5p-PAK3 | Full Text | References | PDF (8.1 MB) | EPUB
  • 87 Views
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Article
CircSKA3 Modulates FOXM1 to Facilitate Cell Proliferation, Migration, and Invasion While Confine Apoptosis in Medulloblastoma via miR-383-5p
Xinfang Wang, Dong Xu, Xin Pei, Yingying Zhang, Yuling Zhang, Yaxing Gu & Ying Li
Pages: 13415-13426
Published online: 30 Dec 2020
AbstractforCircSKA3 Modulates FOXM1 to Facilitate Cell Proliferation, Migration, and Invasion While Confine Apoptosis in Medulloblastoma via miR-383-5p | Full Text | References | PDF (8.8 MB) | EPUB
  • 72 Views
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Article
SLAMF1 Promotes Methotrexate Resistance via Activating Autophagy in Choriocarcinoma Cells
Dazun Shi, Yu Zhang & Yan Tian
Pages: 13427-13436
Published online: 30 Dec 2020
AbstractforSLAMF1 Promotes Methotrexate Resistance via Activating Autophagy in Choriocarcinoma Cells | Full Text | References | PDF (6.1 MB) | EPUB
  • 76 Views
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Article
Identification of Core Genes Involved in the Metastasis of Clear Cell Renal Cell Carcinoma
Rui Peng, Yahui Wang, Likai Mao, Fang Fang & Han Guan
Pages: 13437-13449
Published online: 30 Dec 2020
AbstractforIdentification of Core Genes Involved in the Metastasis of Clear Cell Renal Cell Carcinoma | Full Text | References | PDF (9.9 MB) | EPUB
  • 82 Views
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Article
LncRNA RUNX1-IT1 is Downregulated in Endometrial Cancer and Binds to miR-21 Precursor to Suppress Its Maturation
Minglin Liang, Hongbo Wang, Cong Liu, Tao Lei & Jie Min
Pages: 13451-13459
Published online: 30 Dec 2020
AbstractforLncRNA RUNX1-IT1 is Downregulated in Endometrial Cancer and Binds to miR-21 Precursor to Suppress Its Maturation | Full Text | References | PDF (7.3 MB) | EPUB
  • 80 Views
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Article
CASC8 lncRNA Promotes the Proliferation of Retinoblastoma Cells Through Downregulating miR34a Methylation
Bo Yang, Baoyu Gu, Jing Zhang, Long Xu & Yong Sun
Pages: 13461-13467
Published online: 30 Dec 2020
AbstractforCASC8 lncRNA Promotes the Proliferation of Retinoblastoma Cells Through Downregulating miR34a Methylation | Full Text | References | PDF (4.2 MB) | EPUB
  • 70 Views
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Article
A Comparison Between the Prognosis of Simultaneous and Salvage Radical Resection in Incidental Gallbladder Cancer
Shilin He, Tunan Yu, Parikshit Asutosh Khadaroo, Liuxin Cai, Yeyuan Chu, Fangqiang Wei & Xiao Liang
Pages: 13469-13478
Published online: 30 Dec 2020
AbstractforA Comparison Between the Prognosis of Simultaneous and Salvage Radical Resection in Incidental Gallbladder Cancer | Full Text | References | PDF (2.3 MB) | EPUB
  • 85 Views
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Article
Studies on the Safety and Efficacy of Pyrotinib in the Treatment of HER2- Positive Advanced Solid Tumors Excluding Breast Cancer
Yuzhen Yin, Hui Yang, Zhuo Liu, Jie Tan, Chunrong Zhu, Minbin Chen, Rengui Zhou, Lei Wang & Jun Qian
Pages: 13479-13487
Published online: 30 Dec 2020
AbstractforStudies on the Safety and Efficacy of Pyrotinib in the Treatment of HER2- Positive Advanced Solid Tumors Excluding Breast Cancer | Full Text | References | PDF (2.9 MB) | EPUB
  • 86 Views
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Review

Review Article
Reflections on the Role of Malat1 in Gynecological Cancer
Huiyan Liao, Qi Chen & Jing Xiao
Pages: 13489-13500
Published online: 30 Dec 2020
AbstractforReflections on the Role of Malat1 in Gynecological Cancer | Full Text | References | PDF (2.5 MB) | EPUB
  • 97 Views
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Original Research

Article
Study on Clinical Significance of LncRNA EGOT Expression in Colon Cancer and Its Effect on Autophagy of Colon Cancer Cells
Yang Liu, Bo Zhang, Wen-Bin Cao, Hai-Yan Wang, Lei Niu & Guo-Zhi Zhang
Pages: 13501-13512
Published online: 31 Dec 2020
AbstractforStudy on Clinical Significance of LncRNA EGOT Expression in Colon Cancer and Its Effect on Autophagy of Colon Cancer Cells | Full Text | References | PDF (7.2 MB) | EPUB
  • 71 Views
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Article
Circ_101341 Deteriorates the Progression of Clear Cell Renal Cell Carcinoma Through the miR- 411/EGLN3 Axis
Yongjun Yue, Jinsheng Cui, Yu Zhao, Shangying Liu & Weixing Niu
Pages: 13513-13525
Published online: 31 Dec 2020
AbstractforCirc_101341 Deteriorates the Progression of Clear Cell Renal Cell Carcinoma Through the miR- 411/EGLN3 Axis | Full Text | References | PDF (6.8 MB) | EPUB
  • 69 Views
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Article
Prognostic Value of Autophagy-related Proteins in Human Gastric Cancer
Minmin Wu, Bicheng Chen, Xiaodong Pan & Jiadong Su
Pages: 13527-13540
Published online: 31 Dec 2020
AbstractforPrognostic Value of Autophagy-related Proteins in Human Gastric Cancer | Full Text | References | PDF (6.4 MB) | EPUB
  • 85 Views
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Article
Exosomal miR-499a-5p Inhibits Endometrial Cancer Growth and Metastasis via Targeting VAV3
Liang Jing, Xu Hua, Du Yuanna, Zang Rukun & Mou Junjun
Pages: 13541-13552
Published online: 31 Dec 2020
AbstractforExosomal miR-499a-5p Inhibits Endometrial Cancer Growth and Metastasis via Targeting VAV3 | Full Text | References | PDF (6.4 MB) | EPUB
  • 116 Views
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Review

Review Article
The Dynamic Process and Its Dual Effects on Tumors of Therapy-Induced Senescence
Chenxi Liao, Yin Xiao & Lingbo Liu
Pages: 13553-13566
Published online: 31 Dec 2020
AbstractforThe Dynamic Process and Its Dual Effects on Tumors of Therapy-Induced Senescence | Full Text | References | PDF (1.8 MB) | EPUB
  • 108 Views
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Original Research

Article
Comparison of Diagnostic Efficacy Between Contrast-Enhanced Ultrasound and DCE-MRI for Mass- and Non-Mass-Like Enhancement Types in Breast Lesions
Wei Liu, Min Zong, Hai-yan Gong, Li-jun Ling, Xin-hua Ye, Shui Wang & Cui-ying Li
Pages: 13567-13578
Published online: 31 Dec 2020
AbstractforComparison of Diagnostic Efficacy Between Contrast-Enhanced Ultrasound and DCE-MRI for Mass- and Non-Mass-Like Enhancement Types in Breast Lesions | Full Text | References | PDF (3.9 MB) | EPUB
  • 121 Views
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Article
Analysis of Risk Factors and Clinical Indicators in Bloodstream Infections Among Patients with Hematological Malignancy
Yating Ma, Shijian Wang, Ming Yang, Jinfeng Bao & Chengbin Wang
Pages: 13579-13588
Published online: 31 Dec 2020
AbstractforAnalysis of Risk Factors and Clinical Indicators in Bloodstream Infections Among Patients with Hematological Malignancy | Full Text | References | PDF (2.7 MB) | EPUB
  • 134 Views
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Article
Study on Targeting Relationship Between miR-320b and FGD5-AS1 and Its Effect on Biological Function of Osteosarcoma Cells
Qing-Hua Song, Ming-Jun Guo, Jun-Shui Zheng, Xue-Hong Zheng, Zhao-Hui Ye & Peng Wei
Pages: 13589-13598
Published online: 31 Dec 2020
AbstractforStudy on Targeting Relationship Between miR-320b and FGD5-AS1 and Its Effect on Biological Function of Osteosarcoma Cells | Full Text | References | PDF (5.2 MB) | EPUB
  • 62 Views
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Article
Comparison of Intrafractional Motion in Head and Neck Cancer Between Two Immobilization Methods During Stereotactic Ablative Radiation Therapy by CyberKnife
Chen-Lin Kang, Tsair-Fwu Lee, Shan-Ho Chan, Shyh-Chang Liu, Jui-Chu Wang, Cheng-Hsiang Tsai, Kuan-Cho Liao, Fu-Min Fang, Liyun Chang & Chun-Chieh Huang
Pages: 13599-13606
Published online: 05 Jan 2021
AbstractforComparison of Intrafractional Motion in Head and Neck Cancer Between Two Immobilization Methods During Stereotactic Ablative Radiation Therapy by CyberKnife | Full Text | References | PDF (2.7 MB) | EPUB
  • 207 Views
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Article
Progastrin-Releasing Peptide Precursor and Neuron-Specific Enolase Predict the Efficacy of First-Line Treatment with Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors Among Non-Small-Cell Lung Cancer Patients Harboring EGFR Mutations
Juanjuan Dong, Sihao Tong, Xianfeng Shi, Chao Wang, Xin Xiao, Wenping Ji & Yimian Sun
Pages: 13607-13616
Published online: 05 Jan 2021
AbstractforProgastrin-Releasing Peptide Precursor and Neuron-Specific Enolase Predict the Efficacy of First-Line Treatment with Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors Among Non-Small-Cell Lung Cancer Patients Harboring EGFR Mutations | Full Text | References | PDF (1.4 MB) | EPUB
  • 85 Views
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