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Clinical Pharmacology: Advances and Applications

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Cover image for Clinical Pharmacology: Advances and Applications, Volume 5, 2013

Clinical Pharmacology: Advances and Applications, Volume 5, Issue (2013)

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Clinical Pharmacology: Advances and Applications, Volume 5, Issue (2013)

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Review

Review Article

Advances in the management of glioblastoma: the role of temozolomide and MGMT testing

Reena P Thomas, Lawrence Recht & Seema Nagpal

Pages: 1-9

Published online: 15 Dec 2022

AbstractforAdvances in the management of glioblastoma: the role of temozolomide and MGMT testing | Full Text | References | PDF (279.4 KB)

199 Views
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Open Access

Review Article

Arginine deprivation therapy for malignant melanoma

Jung-Ki Yoon, Arthur E Frankel, Lynn G Feun, Suhendan Ekmekcioglu & Kevin B Kim

Pages: 11-19

Published online: 15 Dec 2022

AbstractforArginine deprivation therapy for malignant melanoma | Full Text | References | PDF (222.7 KB)

92 Views
9 CrossRef citations
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Open Access

Corrigendum

Correction

Update on the management of ulcerative colitis: treatment and maintenance approaches focused on MMX^® mesalamine. [Corrigendum]

Page: 21

Published online: 22 Jan 2013

CitationforUpdate on the management of ulcerative colitis: treatment and maintenance approaches focused on MMX^® mesalamine. [Corrigendum] | Full Text | PDF (70.6 KB)

28 Views
1 CrossRef citations
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Open Access

Original Research

Article

A Phase 1, randomized, open-label crossover study to evaluate the safety and pharmacokinetics of 400 mg albaconazole administered to healthy participants as a tablet formulation versus a capsule formulation

Koen van Rossem & Jenny A Lowe

Pages: 23-31

Published online: 30 Jan 2013

AbstractforA Phase 1, randomized, open-label crossover study to evaluate the safety and pharmacokinetics of 400 mg albaconazole administered to healthy participants as a tablet formulation versus a capsule formulation | Full Text | References | PDF (324.1 KB)

73 Views
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Open Access

Article

Effect of statin therapy on vaspin levels in type 2 diabetic patients

Sayer I Al-Azzam, Karem H Alzoubi, Jaafar Abu Abeeleh, Nizar M Mhaidat & Mahmoud Abu-Abeeleh

Pages: 33-38

Published online: 20 Feb 2013

AbstractforEffect of statin therapy on vaspin levels in type 2 diabetic patients | Full Text | References | PDF (172.8 KB)

54 Views
3 CrossRef citations
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Open Access

Review

Review Article

Differential characteristics of incobotulinumtoxinA and its use in the management of glabellar frown lines

Welf Prager

Pages: 39-52

Published online: 12 Mar 2013

AbstractforDifferential characteristics of incobotulinumtoxinA and its use in the management of glabellar frown lines | Full Text | References | PDF (880.9 KB)

105 Views
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Open Access

Case Report

Newly diagnosed congenital factor VII deficiency and utilization of recombinant activated factor VII (NovoSeven^®)

Nicole S Bartosh, Tara Tomlin, Christian Cable & Kathleen Halka

Pages: 53-58

Published online: 15 Mar 2013

AbstractforNewly diagnosed congenital factor VII deficiency and utilization of recombinant activated factor VII (NovoSeven^®) | Full Text | References | PDF (314.4 KB)

50 Views
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Open Access

Review

Review Article

Epithelial cell-adhesion molecule-directed trifunctional antibody immunotherapy for symptom management of advanced ovarian cancer

Ramez N Eskander & Krishnansu S Tewari

Pages: 55-61

Published online: 03 Oct 2013

AbstractforEpithelial cell-adhesion molecule-directed trifunctional antibody immunotherapy for symptom management of advanced ovarian cancer | Full Text | References | PDF (293.2 KB)

58 Views
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Open Access

Original Research

Article

Effect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

Vijay V Upreti, Yan Song, Jessie Wang, Wonkyung Byon, Rebecca A Boyd, Janice M Pursley, Frank LaCreta & Charles E Frost

Pages: 59-66

Published online: 16 Apr 2013

AbstractforEffect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor | Full Text | References | PDF (238.1 KB)

93 Views
7 CrossRef citations
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Open Access

Review

Review Article

Advances in antiplatelet technologies to improve cardiovascular disease morbidity and mortality: a review of ticagrelor

Estella M Davis, Jon T Knezevich & Robyn M Teply

Pages: 67-83

Published online: 19 Apr 2013

AbstractforAdvances in antiplatelet technologies to improve cardiovascular disease morbidity and mortality: a review of ticagrelor | Full Text | References | PDF (369.1 KB)

72 Views
1 CrossRef citations
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Open Access

Original Research

Article

Differential effects of dosing regimen on the safety and efficacy of dasatinib: retrospective exposure–response analysis of a Phase III study

Xiaoning Wang, Amit Roy, Andreas Hochhaus, Hagop M Kantarjian, Tai-Tsang Chen & Neil P Shah

Pages: 85-97

Published online: 15 Dec 2022

AbstractforDifferential effects of dosing regimen on the safety and efficacy of dasatinib: retrospective exposure–response analysis of a Phase III study | Full Text | References | PDF (3.2 MB)

147 Views
12 CrossRef citations
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Open Access

Review

Review Article

Clinical effectiveness of baclofen for the treatment of alcohol dependence: a review

Jessica L Brennan, Jonathan G Leung, Jane P Gagliardi, Sarah K Rivelli & Andrew J Muzyk

Pages: 99-107

Published online: 15 Dec 2022

AbstractforClinical effectiveness of baclofen for the treatment of alcohol dependence: a review | Full Text | References | PDF (202.2 KB)

187 Views
5 CrossRef citations
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Open Access

Review Article

Synthetic cathinone abuse

Michael Capriola

Pages: 109-115

Published online: 02 Jul 2013

AbstractforSynthetic cathinone abuse | Full Text | References | PDF (223.9 KB)

191 Views
16 CrossRef citations
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Open Access

Review Article

Impact of denosumab on bone mass in cancer patients

Ursa Brown-Glaberman & Alison T Stopeck

Pages: 117-129

Published online: 15 Dec 2022

AbstractforImpact of denosumab on bone mass in cancer patients | Full Text | References | PDF (255 KB)

75 Views
3 CrossRef citations
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Open Access

Review Article

Single-dose fentanyl sublingual spray for breakthrough cancer pain

Donald R Taylor

Pages: 131-141

Published online: 15 Dec 2022

AbstractforSingle-dose fentanyl sublingual spray for breakthrough cancer pain | Full Text | References | PDF (346.4 KB)

123 Views
4 CrossRef citations
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Open Access

Review Article

Comparative safety and efficacy of antithrombotics in the management of venous thromboembolism after knee or hip replacement surgery: focus on rivaroxaban

Louis M Kwong

Pages: 143-148

Published online: 15 Dec 2022

AbstractforComparative safety and efficacy of antithrombotics in the management of venous thromboembolism after knee or hip replacement surgery: focus on rivaroxaban | Full Text | References | PDF (198.2 KB)

53 Views
1 CrossRef citations
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Open Access

Letter

Reviews of botulinum toxin products in aesthetic use must be accurate, clear and avoid speculation

Andy Pickett

Pages: 149-152

Published online: 15 Dec 2022

First Page PreviewforReviews of botulinum toxin products in aesthetic use must be accurate, clear and avoid speculation | Full Text | References | PDF (117.2 KB)

54 Views
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Open Access

Original Research

Article

Atazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model

Roberto Lozano, Nieves Domeque & Alberto-Fermin Apesteguia

Pages: 153-159

Published online: 27 Sep 2013

AbstractforAtazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model | Full Text | References | PDF (313 KB)

54 Views
1 CrossRef citations
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Open Access

Case Series

High-dose, short-interval daptomycin regimen was safe and well tolerated in three patients with chronic renal failure

Kaori Yabuno, Masafumi Seki, Koji Miyawaki, Yoshihiro Miwa & Kazunori Tomono

Pages: 161-166

Published online: 15 Dec 2022

AbstractforHigh-dose, short-interval daptomycin regimen was safe and well tolerated in three patients with chronic renal failure | Full Text | References | PDF (252.1 KB)

47 Views
1 CrossRef citations
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Open Access

Original Research

Article

Preliminary study about the possible glycemic clinical advantage in using a fixed combination of Berberis aristata and Silybum marianum standardized extracts versus only Berberis aristata in patients with type 2 diabetes

Francesco Di Pierro, Pietro Putignano, Nicola Villanova, Luca Montesi, Simona Moscatiello & Giulio Marchesini

Pages: 167-174

Published online: 19 Nov 2013

AbstractforPreliminary study about the possible glycemic clinical advantage in using a fixed combination of Berberis aristata and Silybum marianum standardized extracts versus only Berberis aristata in patients with type 2 diabetes | Full Text | References | PDF (260.4 KB)

330 Views
21 CrossRef citations
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Open Access

Corrigendum

Correction

Atazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model [Corrigendum]

Page: 175

Published online: 22 Nov 2013

CitationforAtazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model [Corrigendum] | Full Text | PDF (121.9 KB)

31 Views
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Open Access

Original Research

Article

Single- and multiple-dose pharmacokinetics, pharmacodynamics, and safety of apixaban in healthy Chinese subjects

Yimin Cui, Yan Song, Jessie Wang, Zhigang Yu, Alan Schuster, Yu Chen Barrett & Charles Frost

Pages: 177-184

Published online: 15 Dec 2022

AbstractforSingle- and multiple-dose pharmacokinetics, pharmacodynamics, and safety of apixaban in healthy Chinese subjects | Full Text | References | PDF (295.2 KB)

265 Views
9 CrossRef citations
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Open Access

Article

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response

Rolf P Kreutz, Janelle Owens, Yan Jin, Perry Nystrom, Zeruesenay Desta, Yvonne Kreutz, Jeffrey A Breall, Lang Li, ChienWei Chiang, Richard J Kovacs & David A Flockhart

Pages: 185-192

Published online: 15 Dec 2022

AbstractforCytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response | Full Text | References | PDF (334.9 KB)

57 Views
4 CrossRef citations
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Open Access

Article

Hemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum

Brian S Decker, Kalisha D O’Neill, Mary A Chambers, James E Slaven, Zhangsheng Yu, David R Jones & Sharon M Moe

Pages: 193-199

Published online: 10 Dec 2013

AbstractforHemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum | Full Text | References | PDF (296.5 KB)

42 Views
2 CrossRef citations
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Open Access

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Clinical Pharmacology: Advances and Applications (Vol.5, Iss., 2013)

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