Clinical Pharmacology: Advances and Applications, Volume 10, Issue (2018)

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Clinical Pharmacology: Advances and Applications, Volume 10, Issue (2018)

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Review

Review Article
A review of the pharmacology and clinical efficacy of brivaracetam
Pavel Klein, Anyzeila Diaz, Teresa Gasalla & John Whitesides
Pages: 1-22
Published online: 19 Jan 2018
AbstractforA review of the pharmacology and clinical efficacy of brivaracetam | Full Text | References | PDF (1.8 MB)
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Original Research

Article
Pramlintide, an antidiabetic, is antineoplastic in colorectal cancer and synergizes with conventional chemotherapy
Maha S Al-Keilani, Dua H Alsmadi, Ruba S Darweesh & Karem H Alzoubi
Pages: 23-29
Published online: 05 Mar 2018
AbstractforPramlintide, an antidiabetic, is antineoplastic in colorectal cancer and synergizes with conventional chemotherapy | Full Text | References | PDF (923.7 KB)
  • 75 Views
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Review

Review Article
Safinamide: an add-on treatment for managing Parkinson’s disease
Thomas Müller
Pages: 31-41
Published online: 05 Apr 2018
AbstractforSafinamide: an add-on treatment for managing Parkinson’s disease | Full Text | References | PDF (236.5 KB)
  • 171 Views
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Original Research

Article
Pharmacokinetic equivalence study of nonsteroidal anti-inflammatory drug etoricoxib
Raymond R Tjandrawinata, Arini Setiawati, Dwi Nofiarny, Liana W Susanto & Effi Setiawati
Pages: 43-51
Published online: 06 Apr 2018
AbstractforPharmacokinetic equivalence study of nonsteroidal anti-inflammatory drug etoricoxib | Full Text | References | PDF (1.6 MB)
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Article
Distribution of pomalidomide into semen of healthy male subjects after multiple doses
Yan Li, Xiaomin Wang, Liangang Liu, Josephine Reyes, Maria Palmisano & Simon Zhou
Pages: 53-62
Published online: 07 May 2018
AbstractforDistribution of pomalidomide into semen of healthy male subjects after multiple doses | Full Text | References | PDF (429.7 KB)
  • 72 Views
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Article
Anti-factor Xa levels in obese patients receiving enoxaparin for treatment and prophylaxis indications
Linda Tahaineh, Sahar M Edaily & Shadi F Gharaibeh
Pages: 63-70
Published online: 18 May 2018
AbstractforAnti-factor Xa levels in obese patients receiving enoxaparin for treatment and prophylaxis indications | Full Text | References | PDF (425.1 KB)
  • 109 Views
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Corrigendum

Correction
A randomized direct comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban [Corrigendum
Page: 71
Published online: 11 Jun 2018
CitationforA randomized direct comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban [Corrigendum | Full Text | PDF (429.6 KB)
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Original Research

Article
Pharmacokinetic evaluation of D-ribose after oral and intravenous administration to healthy rabbits
Karem H Alzoubi, Zuhair Bani Ismail, Mohamed K AL-Essa, Osama Y Alshogran, Reem F Abutayeh & Nareman Abu-Baker
Pages: 73-78
Published online: 12 Jun 2018
AbstractforPharmacokinetic evaluation of D-ribose after oral and intravenous administration to healthy rabbits | Full Text | References | PDF (592.1 KB)
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Article
Safety and neutralizing rabies antibody in healthy subjects given a single dose of rabies immune globulin caprylate/chromatography purified
Kim Hanna, Maria Cristina Cruz, Elsa Mondou, Edward Corsi & Peter Vandeberg
Pages: 79-88
Published online: 26 Jun 2018
AbstractforSafety and neutralizing rabies antibody in healthy subjects given a single dose of rabies immune globulin caprylate/chromatography purified | Full Text | References | PDF (451.4 KB)
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Open Access
Article
A Phase I, open-label, randomized, crossover study in healthy subjects to evaluate the bioavailability of, and the food effect on, a pomalidomide oral liquid suspension
Yan Li, Liangang Liu, Lian Huang, Xiaomin Wang, Matthew Hoffmann, Josephine Reyes, Maria Palmisano & Simon Zhou
Pages: 89-99
Published online: 15 Dec 2022
AbstractforA Phase I, open-label, randomized, crossover study in healthy subjects to evaluate the bioavailability of, and the food effect on, a pomalidomide oral liquid suspension | Full Text | References | PDF (382.2 KB)
  • 139 Views
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Article
Pharmacokinetics of evocalcet in secondary hyperparathyroidism patients receiving hemodialysis: first-in-patient clinical trial in Japan
Takashi Shigematsu, Ryutaro Shimazaki, Masafumi Fukagawa, Tadao Akizawa & On behalf of the Evocalcet Study Group
Pages: 101-111
Published online: 15 Dec 2022
AbstractforPharmacokinetics of evocalcet in secondary hyperparathyroidism patients receiving hemodialysis: first-in-patient clinical trial in Japan | Full Text | References | PDF (436.4 KB)
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Article
Targeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin
Felix Oh, Deborah Todhunter, Elizabeth Taras, Daniel A Vallera & Antonella Borgatti
Pages: 113-121
Published online: 26 Sep 2018
AbstractforTargeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin | Full Text | References | PDF (1.9 MB)
  • 107 Views
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Review

Review Article
Mechanisms and the clinical relevance of complex drug–drug interactions
Arthur G Roberts & Morgan E Gibbs
Pages: 123-134
Published online: 15 Dec 2022
AbstractforMechanisms and the clinical relevance of complex drug–drug interactions | Full Text | References | PDF (561.1 KB)
  • 337 Views
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Original Research

Article
The effect of combined treatment with sodium phenylbutyrate and cisplatin, erlotinib, or gefitinib on resistant NSCLC cells
Maha S Al-Keilani, Karem H Alzoubi & Saied A Jaradat
Pages: 135-140
Published online: 09 Oct 2018
AbstractforThe effect of combined treatment with sodium phenylbutyrate and cisplatin, erlotinib, or gefitinib on resistant NSCLC cells | Full Text | References | PDF (609.8 KB)
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Open Access
Article
12-month effects of incretins versus SGLT2-Inhibitors on cognitive performance and metabolic profile. A randomized clinical trial in the elderly with Type-2 diabetes mellitus
Simone Perna, Manuela Mainardi, Paolo Astrone, Carlotta Gozzer, Anna Biava, Ruben Bacchio, Daniele Spadaccini, Sebastiano Bruno Solerte & Mariangela Rondanelli
Pages: 141-151
Published online: 09 Oct 2018
Abstractfor12-month effects of incretins versus SGLT2-Inhibitors on cognitive performance and metabolic profile. A randomized clinical trial in the elderly with Type-2 diabetes mellitus | Full Text | References | PDF (758.9 KB)
  • 232 Views
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Article
Evaluation of the single-dose pharmacokinetics and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects
Charles Frost, Andrew Shenker, Stanford Jhee, Zhigang Yu, Jessie Wang, Alexander Bragat, Janice Pursley & Frank LaCreta
Pages: 153-163
Published online: 24 Oct 2018
AbstractforEvaluation of the single-dose pharmacokinetics and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects | Full Text | References | PDF (1.8 MB)
  • 118 Views
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Article
Species difference in paclitaxel disposition correlated with poor pharmacological efficacy translation from mice to humans
Ying Fei Li, Chengyue Zhang, Simon Zhou, Miao He, Huixia Zhang, Nianhang Chen, Feng Li, Xin Luan, Manjunath Pai, Hebao Yuan, Duxin Sun & Yan Li
Pages: 165-174
Published online: 08 Nov 2018
AbstractforSpecies difference in paclitaxel disposition correlated with poor pharmacological efficacy translation from mice to humans | Full Text | References | PDF (1.3 MB)
  • 79 Views
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Article
Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
V Mazzarello, MG Donadu, M Ferrari, G Piga, D Usai, S Zanetti & MA Sotgiu
Pages: 175-181
Published online: 15 Dec 2022
AbstractforTreatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations | Full Text | References | PDF (383 KB)
  • 1562 Views
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Article
Correlation between measured and calculated free phenytoin serum concentration in neurointensive care patients with hypoalbuminemia
Seyyede-Sareh Javadi, Reza Mahjub, Abbas Taher, Younes Mohammadi & Maryam Mehrpooya
Pages: 183-190
Published online: 15 Dec 2022
AbstractforCorrelation between measured and calculated free phenytoin serum concentration in neurointensive care patients with hypoalbuminemia | Full Text | References | PDF (226.3 KB)
  • 193 Views
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