Pharmacogenomics and Personalized Medicine, Volume 10, Issue (2017)

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Pharmacogenomics and Personalized Medicine, Volume 10, Issue (2017)

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Original Research

Article
Diet and lifestyle factors associated with miRNA expression in colorectal tissue
Martha L Slattery, Jennifer S Herrick, Lila E Mullany, John R Stevens & Roger K Wolff
Pages: 1-16
Published online: 22 Dec 2022
AbstractforDiet and lifestyle factors associated with miRNA expression in colorectal tissue | Full Text | References | PDF (186.8 KB)
  • 111 Views
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Open Access
Article
Prevalence of clinically actionable genotypes and medication exposure of older adults in the community
Nilofar Daneshi, Elizabeth Holliday, Stephen Hancock, Jennifer J Schneider, Rodney J Scott, John Attia & Elizabeth A Milward
Pages: 17-27
Published online: 22 Dec 2022
AbstractforPrevalence of clinically actionable genotypes and medication exposure of older adults in the community | Full Text | References | PDF (256.7 KB)
  • 54 Views
  • 1 CrossRef citations
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Open Access

Review

Review Article
The HLA-A*31:01 allele: influence on carbamazepine treatment
Vincent Lai Ming Yip & Munir Pirmohamed
Pages: 29-38
Published online: 22 Dec 2022
AbstractforThe HLA-A*31:01 allele: influence on carbamazepine treatment | Full Text | References | PDF (2.8 MB)
  • 117 Views
  • 27 CrossRef citations
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Open Access

Original Research

Article
Increased risk of hospitalization for ultrarapid metabolizers of cytochrome P450 2D6
Paul Y Takahashi, Euijung Ryu, Jyotishman Pathak, Gregory D Jenkins, Anthony Batzler, Matthew A Hathcock, John Logan Black, Janet E Olson, James R Cerhan & Suzette J Bielinski
Pages: 39-47
Published online: 22 Dec 2022
AbstractforIncreased risk of hospitalization for ultrarapid metabolizers of cytochrome P450 2D6 | Full Text | References | PDF (544.1 KB)
  • 104 Views
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Open Access

Review

Review Article
Is there evidence that we should screen the general population for Lynch syndrome with genetic testing? A systematic review
Anya E R Prince, R Jean Cadigan, Gail E Henderson, James P Evans, Michael Adams, Emmanuel Coker-Schwimmer, Dolly C Penn, Marcia Van Riper, Giselle Corbie-Smith & Daniel E Jonas
Pages: 49-60
Published online: 22 Dec 2022
AbstractforIs there evidence that we should screen the general population for Lynch syndrome with genetic testing? A systematic review | Full Text | References | PDF (315.3 KB)
  • 87 Views
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Open Access
Review Article
UGT1A1 polymorphisms in cancer: impact on irinotecan treatment
Masashi Takano & Toru Sugiyama
Pages: 61-68
Published online: 28 Feb 2017
AbstractforUGT1A1 polymorphisms in cancer: impact on irinotecan treatment | Full Text | References | PDF (482.6 KB)
  • 307 Views
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Open Access
Review Article
MTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy
Maitane Umerez, Ángela Gutierrez-Camino, Carmen Muñoz-Maldonado, Idoia Martin-Guerrero & Africa Garcia-Orad
Pages: 69-78
Published online: 27 Mar 2017
AbstractforMTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy | Full Text | References | PDF (446 KB)
  • 93 Views
  • 10 CrossRef citations
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Open Access
Review Article
Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals
Julieta Trinks, Mariela Caputo, María L Hulaniuk, Daniel Corach & Diego Flichman
Pages: 79-91
Published online: 22 Dec 2022
AbstractforHepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals | Full Text | References | PDF (3.2 MB)
  • 62 Views
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Open Access

Original Research

Article
Comparison of CYP2C9, CYP2C19, CYP2D6, ABCB1, and SLCO1B1 gene-polymorphism frequency in Russian and Nanai populations
Dmitrij Alekseevitch Sychev, Grigorij Nikolaevich Shuev, Salavat Shejhovich Suleymanov, Kristina Anatol’evna Ryzhikova, Karin Badavievich Mirzaev, Elena Anatol’evna Grishina, Natalia Evgenievna Snalina, Zhannet Alimovna Sozaeva, Anton Mikhailovich Grabuzdov & Irina Andreevna Matsneva
Pages: 93-99
Published online: 31 Mar 2017
AbstractforComparison of CYP2C9, CYP2C19, CYP2D6, ABCB1, and SLCO1B1 gene-polymorphism frequency in Russian and Nanai populations | Full Text | References | PDF (174 KB)
  • 75 Views
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Open Access
Article
Association of the PPP3CA c.249G>A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients
Patricia C Salgado, Fabiana DV Genvigir, Claudia R Felipe, Helio Tedesco-Silva Jr, Jose O Medina-Pestana, Sonia Q Doi, Mario H Hirata & Rosario DC Hirata
Pages: 101-106
Published online: 31 Mar 2017
AbstractforAssociation of the PPP3CA c.249G>A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients | Full Text | References | PDF (149.3 KB)
  • 61 Views
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Open Access
Article
CYP2C19 polymorphism frequency in Russian patients in Central Russia and Siberia with acute coronary syndrome
Karin B Mirzaev, Elena M Zelenskaya, Olga L Barbarash, Vladimir I Ganyukov, Konstantin A Apartsin, Natalya O Saraeva, Konstantin Y Nikolaev, Kristina A Ryzhikova, Galina I Lifshits & Dmitry A Sychev
Pages: 107-114
Published online: 12 Apr 2017
AbstractforCYP2C19 polymorphism frequency in Russian patients in Central Russia and Siberia with acute coronary syndrome | Full Text | References | PDF (201.3 KB)
  • 67 Views
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Open Access

Methodology

Article
Pharmacogenetic testing revisited: 5′ nuclease real-time polymerase chain reaction test panels for genotyping CYP2D6 and CYP2C19
Jens Borggaard Larsen & Jan Borg Rasmussen
Pages: 115-128
Published online: 18 Apr 2017
AbstractforPharmacogenetic testing revisited: 5′ nuclease real-time polymerase chain reaction test panels for genotyping CYP2D6 and CYP2C19 | Full Text | References | PDF (633.4 KB)
  • 74 Views
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Open Access

Review

Review Article
ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches
MC Cleophas, LA Joosten, LK Stamp, N Dalbeth, OM Woodward & Tony R Merriman
Pages: 129-142
Published online: 20 Apr 2017
AbstractforABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches | Full Text | References | PDF (2.6 MB)
  • 243 Views
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Open Access
Review Article
Thiopurine S-methyltransferase polymorphisms in acute lymphoblastic leukemia, inflammatory bowel disease and autoimmune disorders: influence on treatment response
Rachid Abaji & Maja Krajinovic
Pages: 143-156
Published online: 05 May 2017
AbstractforThiopurine S-methyltransferase polymorphisms in acute lymphoblastic leukemia, inflammatory bowel disease and autoimmune disorders: influence on treatment response | Full Text | References | PDF (373.4 KB)
  • 146 Views
  • 7 CrossRef citations
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Open Access

Original Research

Article
DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion
Vidya Chidambaran, Xue Zhang, Lisa J Martin, Lili Ding, Matthew T Weirauch, Kristie Geisler, Bobbie L Stubbeman, Senthilkumar Sadhasivam & Hong Ji
Pages: 157-168
Published online: 09 May 2017
AbstractforDNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion | Full Text | References | PDF (432.8 KB)
  • 133 Views
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Open Access

Review

Review Article
ABCB1 genetic variants in leukemias: current insights into treatment outcomes
Ravindran Ankathil
Pages: 169-181
Published online: 12 May 2017
AbstractforABCB1 genetic variants in leukemias: current insights into treatment outcomes | Full Text | References | PDF (245.2 KB)
  • 125 Views
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Open Access

Short Report

Brief Report
CYP2C19*2 status in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis
Amanda J Laska, Marie J Han, Josh A Lospinoso, Patrick J Brown & Thomas M Beachkofsky
Pages: 183-186
Published online: 17 May 2017
AbstractforCYP2C19*2 status in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis | Full Text | References | PDF (200.8 KB)
  • 70 Views
  • 5 CrossRef citations
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Open Access

Original Research

Article
Observational study to calculate addictive risk to opioids: a validation study of a predictive algorithm to evaluate opioid use disorder
Ashley Brenton, Steven Richeimer, Maneesh Sharma, Chee Lee, Svetlana Kantorovich, John Blanchard & Brian Meshkin
Pages: 187-195
Published online: 22 Dec 2022
AbstractforObservational study to calculate addictive risk to opioids: a validation study of a predictive algorithm to evaluate opioid use disorder | Full Text | References | PDF (409.9 KB)
  • 149 Views
  • 8 CrossRef citations
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Open Access

Review

Review Article
Pharmacogenetics in inflammatory bowel disease: understanding treatment response and personalizing therapeutic strategies
Jesús K Yamamoto-Furusho
Pages: 197-204
Published online: 22 Dec 2022
AbstractforPharmacogenetics in inflammatory bowel disease: understanding treatment response and personalizing therapeutic strategies | Full Text | References | PDF (192.6 KB)
  • 90 Views
  • 7 CrossRef citations
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Open Access
Review Article
Hyperbilirubinemia in atazanavir treated HIV-infected patients: the impact of the UGT1A1*28 allele
Periklis Panagopoulos, Efstathios Maltezos, Angelos Hatzakis & Dimitrios Paraskevis
Pages: 205-208
Published online: 22 Dec 2022
AbstractforHyperbilirubinemia in atazanavir treated HIV-infected patients: the impact of the UGT1A1*28 allele | Full Text | References | PDF (146.5 KB)
  • 87 Views
  • 2 CrossRef citations
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Open Access

Original Research

Article
Pharmacodynamic genetic polymorphisms affect adverse drug reactions of haloperidol in patients with alcohol-use disorder
Mikhail Sergeevich Zastrozhin, Vadim Markovich Brodyansky, Valentin Yurievich Skryabin, Elena Anatolievna Grishina, Dmitry Vladimirovich Ivashchenko, Kristina Anatolievna Ryzhikova, Ludmila Mikhaylovna Savchenko, Alexander Olegovich Kibitov, Evgeny Alekseevich Bryun & Dmitry Alekseevich Sychev
Pages: 209-215
Published online: 22 Dec 2022
AbstractforPharmacodynamic genetic polymorphisms affect adverse drug reactions of haloperidol in patients with alcohol-use disorder | Full Text | References | PDF (202.7 KB)
  • 142 Views
  • 8 CrossRef citations
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Open Access
Article
CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications
Jennifer L St Sauver, Janet E Olson, Veronique L Roger, Wayne T Nicholson, John L Black III, Paul Y Takahashi, Pedro J Caraballo, Elizabeth J Bell, Debra J Jacobson, Nicholas B Larson & Suzette J Bielinski
Pages: 217-227
Published online: 22 Dec 2022
AbstractforCYP2D6 phenotypes are associated with adverse outcomes related to opioid medications | Full Text | References | PDF (197.6 KB)
  • 168 Views
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Open Access

Review

Review Article
Updating the landscape of direct-to-consumer pharmacogenomic testing
Kelly K Filipski, John D Murphy & Kathy J Helzlsouer
Pages: 229-232
Published online: 22 Dec 2022
AbstractforUpdating the landscape of direct-to-consumer pharmacogenomic testing | Full Text | References | PDF (110.7 KB)
  • 67 Views
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Open Access

Letter

Letter
Hyperbilirubinemia in atazanavir-treated human immunodeficiency virus-infected patients: the impact of the UGT1A1*28 allele
Anushka Naidoo, Kogieleum Naidoo, Veron Ramsuran, Millidhashni Reddy & Nesri Padayatchi
Pages: 233-234
Published online: 23 Aug 2017
CitationforHyperbilirubinemia in atazanavir-treated human immunodeficiency virus-infected patients: the impact of the UGT1A1*28 allele | Full Text | References | PDF (140.5 KB)
  • 93 Views
  • 0 CrossRef citations
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Open Access

Original Research

Article
ABCB1 and ABCC1 single-nucleotide polymorphisms in patients treated with clozapine
Irina Piatkov, Dorgival Caetano, Yolinda Assur, Sue Lynn Lau, Trudi Jones, Steven C Boyages & Mark McLean
Pages: 235-242
Published online: 28 Aug 2017
AbstractforABCB1 and ABCC1 single-nucleotide polymorphisms in patients treated with clozapine | Full Text | References | PDF (497.4 KB)
  • 86 Views
  • 13 CrossRef citations
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Open Access
Article
Do CYP2C19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?
Eric Rytkin, Karin B Mirzaev, Elena A Grishina, Valeriy V Smirnov, Kristina A Ryzhikova, Zhannet A Sozaeva, Michael Iu Giliarov, Denis A Andreev & Dmitriy A Sychev
Pages: 243-245
Published online: 18 Sep 2017
AbstractforDo CYP2C19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients? | Full Text | References | PDF (113 KB)
  • 59 Views
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Open Access

Perspectives

Article
Pharmacogenomic testing: aiding in the management of psychotropic therapy for adolescents with autism spectrum disorders
Seuli Bose-Brill, Jinming Xing, Debra J Barnette & Christopher Hanks
Pages: 247-252
Published online: 25 Sep 2017
AbstractforPharmacogenomic testing: aiding in the management of psychotropic therapy for adolescents with autism spectrum disorders | Full Text | References | PDF (129.3 KB)
  • 91 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Urine metabolic ratio of omeprazole in relation to CYP2C19 polymorphisms in Russian peptic ulcer patients
Natalia P Denisenko, Dmitriy A Sychev, Zhanna M Sizova, Valeriy V Smirnov, Kristina A Ryzhikova, Zhannet A Sozaeva & Elena A Grishina
Pages: 253-259
Published online: 27 Sep 2017
AbstractforUrine metabolic ratio of omeprazole in relation to CYP2C19 polymorphisms in Russian peptic ulcer patients | Full Text | References | PDF (393.2 KB)
  • 88 Views
  • 6 CrossRef citations
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Open Access

Review

Review Article
Pharmacogenomics of sickle cell disease: steps toward personalized medicine
Marium Husain, Amber D Hartman & Payal Desai
Pages: 261-265
Published online: 19 Oct 2017
AbstractforPharmacogenomics of sickle cell disease: steps toward personalized medicine | Full Text | References | PDF (133.8 KB)
  • 158 Views
  • 1 CrossRef citations
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Open Access
Review Article
Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran
Malak Rizk & Şükrü Tüzmen
Pages: 267-278
Published online: 10 Nov 2017
AbstractforUpdate on the clinical utility of an RNA interference-based treatment: focus on Patisiran | Full Text | References | PDF (1.8 MB)
  • 206 Views
  • 21 CrossRef citations
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Open Access

Original Research

Article
Ethiopian health care professionals’ knowledge, attitude, and interests toward pharmacogenomics
Ousman Abubeker Abdela, Akshaya Srikanth Bhagavathula, Eyob Alemayehu Gebreyohannes & Henok Getachew Tegegn
Pages: 279-285
Published online: 05 Dec 2017
AbstractforEthiopian health care professionals’ knowledge, attitude, and interests toward pharmacogenomics | Full Text | References | PDF (196.2 KB)
  • 197 Views
  • 11 CrossRef citations
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Open Access

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