The American Journal of Drug and Alcohol Abuse, Volume 37, Issue 5 (2011)

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The American Journal of Drug and Alcohol Abuse, Volume 37, Issue 5 (2011)

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The Clinical Trials Network: A Decade of Progress (Guest Editor: Edward Nunes)

Research Articles

Article
The Design and Analysis of Multisite Effectiveness Trials: A Decade of Progress in the National Drug Abuse Clinical Trials Network
Edward V. Nunes M.D.
Pages: 269-272
Published online: 22 Aug 2011
First Page PreviewforThe Design and Analysis of Multisite Effectiveness Trials: A Decade of Progress in the National Drug Abuse Clinical Trials Network | Full Text | References | PDF (90.4 KB)
  • 183 Views
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Obituary

In memory of Dr. Malcolm S. Reid PhD
Pages: 273-274
Published online: 22 Aug 2011
CitationforIn memory of Dr. Malcolm S. Reid PhD | Full Text | PDF (155.1 KB)
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Research Articles

Article
Ten Take Home Lessons from the First 10 Years of the CTN and 10 Recommendations for the Future
Kathleen M. Carroll Ph.D., Samuel A. Ball Ph.D., Ron Jackson M.S.W., Steve Martino Ph.D., Nancy M. Petry Ph.D., Maxine L. Stitzer Ph.D., Elizabeth A. Wells Ph.D. & Roger D. Weiss Ph.D.
Pages: 275-282
Published online: 22 Aug 2011
AbstractforTen Take Home Lessons from the First 10 Years of the CTN and 10 Recommendations for the Future | Full Text | References | PDF (113.8 KB)
  • 309 Views
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Article
NIDA’s Clinical Trials Network: An Opportunity for HIV Research in Community Substance Abuse Treatment Programs
Susan Tross Ph.D., Aimee N. C. Campbell Ph.D., Donald A. Calsyn Ph.D., Lisa R. Metsch Ph.D., James L. Sorensen Ph.D., Steven Shoptaw Ph.D., Louise Haynes M.S.W., George E. Woody M.D., Robert M. Malow Ph.D., Lawrence S. Brown Jr. M.D., M.P.H., Daniel J. Feaster Ph.D., Robert E. Booth Ph.D., Raul N. Mandler M.D., Carmen Masson Ph.D., Beverly W. Holmes M.S.W., Grant Colfax M.D., Audrey J. Brooks Ph.D., Denise A. Hien Ph.D., Bruce R. Schackman Ph.D., P. Todd Korthuis M.D., M.P.H., Gloria M. Miele Ph.D. & Clinical Trials Network HIV Special Interest Group
Pages: 283-293
Published online: 22 Aug 2011
AbstractforNIDA’s Clinical Trials Network: An Opportunity for HIV Research in Community Substance Abuse Treatment Programs | Full Text | References | PDF (135.3 KB)
  • 241 Views
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Article
Is Monogamy or Committed Relationship Status a Marker for Low Sexual Risk among Men in Substance Abuse Treatment? Clinical and Methodological Considerations
Donald A. Calsyn Ph.D., Aimee N. Campbell Ph.D., Susan Tross Ph.D. & Mary A. Hatch-Maillette Ph.D.
Pages: 294-300
Published online: 22 Aug 2011
AbstractforIs Monogamy or Committed Relationship Status a Marker for Low Sexual Risk among Men in Substance Abuse Treatment? Clinical and Methodological Considerations | Full Text | References | PDF (196.1 KB)
  • 137 Views
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Article
Gender Research in the National Institute on Drug Abuse National Treatment Clinical Trials Network: A Summary of Findings
Shelly F. Greenfield M.D., M.P.H., Carmen Rosa M.S., Susan I. Putnins B.A., Carla A. Green Ph.D., M.P.H., Audrey J. Brooks Ph.D., Donald A. Calsyn Ph.D., Lisa R. Cohen Ph.D., Sarah Erickson Ph.D., Susan M. Gordon Ph.D., Louise Haynes M.S.W., Therese Killeen Ph.D., Gloria Miele Ph.D., Susan Tross Ph.D. & Theresa Winhusen Ph.D.
Pages: 301-312
Published online: 22 Aug 2011
AbstractforGender Research in the National Institute on Drug Abuse National Treatment Clinical Trials Network: A Summary of Findings | Full Text | References | PDF (133.4 KB)
  • 692 Views
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Article
Comparative Profiles of Men and Women with Opioid Dependence: Results from a National Multisite Effectiveness Trial
Sudie E. Back Ph.D., Rebecca L. Payne M.D., Amy Herrin Wahlquist M.S., Rickey E. Carter Ph.D., Zachary Stroud M.D., Louise Haynes M.S.W., Maureen Hillhouse Ph.D., Kathleen T. Brady M.D., Ph.D. & Walter Ling M.D.
Pages: 313-323
Published online: 22 Aug 2011
AbstractforComparative Profiles of Men and Women with Opioid Dependence: Results from a National Multisite Effectiveness Trial | Full Text | References | PDF (151.3 KB)
  • 1385 Views
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Article
Conducting Research with Racial/Ethnic Minorities: Methodological Lessons from the NIDA Clinical Trials Network
A. Kathleen Burlew Ph.D., Jerren C. Weekes M.A., La’Trice Montgomery M.A., Daniel J. Feaster Ph.D., Michael S. Robbins Ph.D., Carmen L. Rosa M.S., Lesia M. Ruglass Ph.D., Kamilla L. Venner Ph.D. & Li-Tzy Wu Sc.D.
Pages: 324-332
Published online: 22 Aug 2011
AbstractforConducting Research with Racial/Ethnic Minorities: Methodological Lessons from the NIDA Clinical Trials Network | Full Text | References | PDF (122.7 KB)
  • 662 Views
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Article
Research Partnerships between Academic Institutions and American Indian and Alaska Native Tribes and Organizations: Effective Strategies and Lessons Learned in a Multisite CTN Study
Lisa Rey Thomas Ph.D., Carmen Rosa M.S., Alyssa Forcehimes Ph.D. & Dennis M. Donovan Ph.D.
Pages: 333-338
Published online: 22 Aug 2011
AbstractforResearch Partnerships between Academic Institutions and American Indian and Alaska Native Tribes and Organizations: Effective Strategies and Lessons Learned in a Multisite CTN Study | Full Text | References | PDF (101.1 KB)
  • 579 Views
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Article
Determining the Primary Endpoint for a Stimulant Abuse Trial: Lessons Learned from STRIDE (CTN 0037)
Madhukar H. Trivedi M.D., Tracy L. Greer Ph.D., Jennifer Sharpe Potter Ph.D., M.P.H., Bruce D. Grannemann M.A., Edward V. Nunes M.D., Chad Rethorst Ph.D., Diane Warden Ph.D., M.B.A., Kolette M. Ring B.A. & Eugene Somoza M.D., Ph.D.
Pages: 339-349
Published online: 22 Aug 2011
AbstractforDetermining the Primary Endpoint for a Stimulant Abuse Trial: Lessons Learned from STRIDE (CTN 0037) | Full Text | References | PDF (171.5 KB)
  • 212 Views
  • 10 CrossRef citations
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Article
Power of Automated Algorithms for Combining Time-Line Follow-Back and Urine Drug Screening Test Results in Stimulant-Abuse Clinical Trials
Neal L. Oden Ph.D., Paul C. VanVeldhuisen Ph.D., Paul G. Wakim Ph.D., Madhukar H. Trivedi M.D., Eugene Somoza M.D., Ph.D. & Daniel Lewis B.A.
Pages: 350-357
Published online: 22 Aug 2011
AbstractforPower of Automated Algorithms for Combining Time-Line Follow-Back and Urine Drug Screening Test Results in Stimulant-Abuse Clinical Trials | Full Text | References | PDF (3.3 MB)
  • 197 Views
  • 10 CrossRef citations
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Article
Assessing Drug Use during Follow-Up: Direct Comparison of Candidate Outcome Definitions in Pooled Analyses of Addiction Treatment Studies
Jeffrey E. Korte M.S.P.H., Ph.D., Kathryn M. Magruder M.P.H., Ph.D., Codruta C. Chiuzan M.S., Sarah L. Logan M.S., Therese Killeen Ph.D., Dipankar Bandyopadhyay Ph.D. & Kathleen T. Brady M.D., Ph.D.
Pages: 358-366
Published online: 22 Aug 2011
AbstractforAssessing Drug Use during Follow-Up: Direct Comparison of Candidate Outcome Definitions in Pooled Analyses of Addiction Treatment Studies | Full Text | References | PDF (111.1 KB)
  • 247 Views
  • 9 CrossRef citations
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Article
Zero-Inflated and Hurdle Models of Count Data with Extra Zeros: Examples from an HIV-Risk Reduction Intervention Trial
Mei-Chen Hu Ph.D., Martina Pavlicova Ph.D. & Edward V. Nunes M.D.
Pages: 367-375
Published online: 22 Aug 2011
AbstractforZero-Inflated and Hurdle Models of Count Data with Extra Zeros: Examples from an HIV-Risk Reduction Intervention Trial | Full Text | References | PDF (269.1 KB)
  • 2437 Views
  • 201 CrossRef citations
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Article
Some Considerations for Excess Zeroes in Substance Abuse Research
Dipankar Bandyopadhyay Ph.D., Stacia M. DeSantis Ph.D., Jeffrey E. Korte M.S.P.H., Ph.D. & Kathleen T. Brady M.D., Ph.D.
Pages: 376-382
Published online: 22 Aug 2011
AbstractforSome Considerations for Excess Zeroes in Substance Abuse Research | Full Text | References | PDF (155.6 KB)
  • 234 Views
  • 30 CrossRef citations
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Article
Modeling Site Effects in the Design and Analysis of Multi-site Trials
Daniel J. Feaster Ph.D., Susan Mikulich-Gilbertson Ph.D. & Ahnalee M. Brincks M.A.
Pages: 383-391
Published online: 22 Aug 2011
AbstractforModeling Site Effects in the Design and Analysis of Multi-site Trials | Full Text | References | PDF (127.7 KB)
  • 613 Views
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Article
An Exploration of Site Effects in a Multisite Trial of OROS-Methylphenidate for Smokers with Attention Deficit/Hyperactivity Disorder
Lirio S. Covey Ph.D., Mei-Chen Hu Ph.D., Carla A. Green Ph.D., M.P.H., Gregory Brigham Ph.D., Richard D. Hurt M.D., Lenard Adler M.D. & Theresa Winhusen Ph.D.
Pages: 392-399
Published online: 22 Aug 2011
AbstractforAn Exploration of Site Effects in a Multisite Trial of OROS-Methylphenidate for Smokers with Attention Deficit/Hyperactivity Disorder | Full Text | References | PDF (151 KB)
  • 169 Views
  • 9 CrossRef citations
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Article
Site Selection in Community-Based Clinical Trials for Substance Use Disorders: Strategies for Effective Site Selection
Jennifer Sharpe Potter Ph.D., M.P.H., Dennis M. Donovan Ph.D., Roger D. Weiss M.D., John Gardin Ph.D., Robert Lindblad M.D., Paul Wakim Ph.D. & Dorian Dodd B.A.
Pages: 400-407
Published online: 22 Aug 2011
AbstractforSite Selection in Community-Based Clinical Trials for Substance Use Disorders: Strategies for Effective Site Selection | Full Text | References | PDF (111.5 KB)
  • 271 Views
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Article
How Practice and Science Are Balanced and Blended in the NIDA Clinical Trials Network: The Bidirectional Process in the Development of the STAGE-12 Protocol as an Example
Dennis M. Donovan Ph.D., Dennis C. Daley Ph.D., Gregory S. Brigham Ph.D., Candace C. Hodgkins Ph.D., Harold I. Perl Ph.D. & Anthony S. Floyd Ph.D.
Pages: 408-416
Published online: 22 Aug 2011
AbstractforHow Practice and Science Are Balanced and Blended in the NIDA Clinical Trials Network: The Bidirectional Process in the Development of the STAGE-12 Protocol as an Example | Full Text | References | PDF (121.1 KB)
  • 116 Views
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Article
Design of NIDA CTN Protocol 0047: Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED)
Michael P. Bogenschutz M.D., Dennis M. Donovan Ph.D., Bryon Adinoff M.D., Cameron Crandall M.D., Ph.D., Alyssa A. Forcehimes Ph.D., Robert Lindblad M.D., Raul N. Mandler M.D., Neal L. Oden Ph.D., Harold I. Perl Ph.D. & Robrina Walker Ph.D.
Pages: 417-425
Published online: 22 Aug 2011
AbstractforDesign of NIDA CTN Protocol 0047: Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED) | Full Text | References | PDF (199.4 KB)
  • 414 Views
  • 20 CrossRef citations
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Article
Relation of Study Design to Recruitment and Retention in CTN Trials
Paul G. Wakim Ph.D., Carmen Rosa M.S., Prasad Kothari M.S. & Mary Ellen Michel Ph.D.
Pages: 426-433
Published online: 22 Aug 2011
AbstractforRelation of Study Design to Recruitment and Retention in CTN Trials | Full Text | References | PDF (107.9 KB)
  • 171 Views
  • 8 CrossRef citations
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Article
Standardized Patient Walkthroughs in the National Drug Abuse Treatment Clinical Trials Network: Common Challenges to Protocol Implementation
Holly E. Fussell Ph.D., Lynn E. Kunkel M.S., CCRP, Dennis McCarty Ph.D. & Colleen S. Lewy Ph.D.
Pages: 434-439
Published online: 22 Aug 2011
AbstractforStandardized Patient Walkthroughs in the National Drug Abuse Treatment Clinical Trials Network: Common Challenges to Protocol Implementation | Full Text | References | PDF (97.4 KB)
  • 140 Views
  • 2 CrossRef citations
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Article
Strategies for Safety Reporting in Substance Abuse Trials
Robert Lindblad M.D., F.A.C.E.P., Maria Campanella B.S.N., David Styers B.S., Prasad Kothari M.S., Steve Sparenborg Ph.D. & Carmen Rosa M.S.
Pages: 440-445
Published online: 22 Aug 2011
AbstractforStrategies for Safety Reporting in Substance Abuse Trials | Full Text | References | PDF (97.2 KB)
  • 108 Views
  • 3 CrossRef citations
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Article
Baseline Matters: The Importance of Covariation for Baseline Severity in the Analysis of Clinical Trials
Edward V. Nunes M.D., Martina Pavlicova Ph.D., Mei-Chen Hu Ph.D., Aimee N. Campbell Ph.D., Gloria Miele Ph.D., Denise Hien Ph.D. & Donald F. Klein M.D.
Pages: 446-452
Published online: 22 Aug 2011
AbstractforBaseline Matters: The Importance of Covariation for Baseline Severity in the Analysis of Clinical Trials | Full Text | References | PDF (201.3 KB)
  • 452 Views
  • 33 CrossRef citations
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Article
Participant Characteristics and Buprenorphine Dose
Maureen Hillhouse Ph.D., Catherine P. Canamar Ph.D., Geetha Doraimani M.S., Christie Thomas M.P.H., Albert Hasson M.S.W. & Walter Ling M.D.
Pages: 453-459
Published online: 22 Aug 2011
AbstractforParticipant Characteristics and Buprenorphine Dose | Full Text | References | PDF (121.5 KB)
  • 385 Views
  • 25 CrossRef citations
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Article
Rates and Influences of Alcohol Use Disorder Comorbidity among Primary Stimulant Misusing Treatment-Seekers: Meta-analytic Findings Across Eight NIDA CTN Trials
Bryan Hartzler Ph.D., Dennis M. Donovan Ph.D. & Zhen Huang M.S.
Pages: 460-471
Published online: 22 Aug 2011
AbstractforRates and Influences of Alcohol Use Disorder Comorbidity among Primary Stimulant Misusing Treatment-Seekers: Meta-analytic Findings Across Eight NIDA CTN Trials | Full Text | References | PDF (120.7 KB)
  • 200 Views
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Article
Smoking Cessation Treatment among Patients in Community-Based Substance Abuse Rehabilitation Programs: Exploring Predictors of Outcome as Clues Toward Treatment Improvement
Malcolm S. Reid Ph.D., Huiping Jiang Ph.D., Bryan Fallon Ph.D., Susan Sonne Pharm.D., Paul Rinaldi Ph.D., Eva Turrigiano B.S., Cynthia Arfken Ph.D., James Robinson M.Ed., John Rotrosen M.D. & Edward V. Nunes M.D.
Pages: 472-478
Published online: 22 Aug 2011
AbstractforSmoking Cessation Treatment among Patients in Community-Based Substance Abuse Rehabilitation Programs: Exploring Predictors of Outcome as Clues Toward Treatment Improvement | Full Text | References | PDF (113.8 KB)
  • 467 Views
  • 14 CrossRef citations
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