Current Medical Research and Opinion, Volume 26, Issue 10 (2010)

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Current Medical Research and Opinion, Volume 26, Issue 10 (2010)

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Original Article

Article
Impact of solifenacin on diary-recorded and patient-reported urgency in patients with severe overactive bladder (OAB) symptoms
Scott R. Serels, Marc R. Toglia, Sergio Forero-Schwanhaeuser & Weizhong He
Pages: 2277-2285
Published online: 16 Aug 2010
AbstractforImpact of solifenacin on diary-recorded and patient-reported urgency in patients with severe overactive bladder (OAB) symptoms | Full Text | References | PDF (216.8 KB)
  • 392 Views
  • 13 CrossRef citations
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Brief Review

Review Article
Clinical development of onercept, a tumor necrosis factor binding protein, in psoriasis
Kim Papp
Pages: 2287-2300
Published online: 18 Aug 2010
AbstractforClinical development of onercept, a tumor necrosis factor binding protein, in psoriasis | Full Text | References | PDF (276.2 KB) | Supplemental
  • 221 Views
  • 9 CrossRef citations
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Original Article

Article
Effect of increasing doses of Rosuvastatin and Atorvastatin on apolipoproteins, enzymes and lipid transfer proteins involved in lipoprotein metabolism and inflammatory parameters
Ioannis K. Karalis, Sandrin C. Bergheanu, Ron Wolterbeek, Geesje M. Dallinga-Thie, Hiroaki Hattori, Arie van Tol, Anho H. Liem & J. Wouter Jukema
Pages: 2301-2313
Published online: 23 Aug 2010
AbstractforEffect of increasing doses of Rosuvastatin and Atorvastatin on apolipoproteins, enzymes and lipid transfer proteins involved in lipoprotein metabolism and inflammatory parameters | Full Text | References | PDF (467.6 KB)
  • 344 Views
  • 22 CrossRef citations
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Article
Cost effectiveness of letrozole versus anastrozole in postmenopausal women with HR+ early-stage breast cancer
Michael Lipsitz, Thomas E. Delea & Amy Guo
Pages: 2315-2328
Published online: 23 Aug 2010
AbstractforCost effectiveness of letrozole versus anastrozole in postmenopausal women with HR+ early-stage breast cancer | Full Text | References | PDF (224.5 KB)
  • 471 Views
  • 6 CrossRef citations
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Review

Review Article
Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate
Jon I. Williams, James A. Gow, Sharon M. Klier, Shannon L. McCue, Anne Marie F. Salapatek & Timothy R. McNamara
Pages: 2329-2338
Published online: 25 Aug 2010
AbstractforNon-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate | Full Text | References | PDF (182.6 KB)
  • 600 Views
  • 17 CrossRef citations
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Original Article

Article
A randomized, double-blind, placebo-controlled, dose ranging study to assess the efficacy and safety of eltrombopag in patients receiving carboplatin/paclitaxel for advanced solid tumors
A. Kellum, A. Jagiello-Gruszfeld, I.N. Bondarenko, R. Patwardhan, C. Messam & Y. Mostafa Kamel
Pages: 2339-2346
Published online: 25 Aug 2010
AbstractforA randomized, double-blind, placebo-controlled, dose ranging study to assess the efficacy and safety of eltrombopag in patients receiving carboplatin/paclitaxel for advanced solid tumors | Full Text | References | PDF (274.8 KB)
  • 1260 Views
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Brief Report

Brief Report
Insulin pharmacokinetics following dosing with Technosphere insulin in subjects with chronic obstructive pulmonary disease
Elizabeth Potocka, Nikhil Amin, James Cassidy, Sherwyn L. Schwartz, Madison Gray, Peter C. Richardson & Robert A. Baughman
Pages: 2347-2353
Published online: 31 Aug 2010
AbstractforInsulin pharmacokinetics following dosing with Technosphere insulin in subjects with chronic obstructive pulmonary disease | Full Text | References | PDF (187.6 KB)
  • 266 Views
  • 10 CrossRef citations
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Original Article

Article
Saxagliptin and metformin XR combination therapy provides glycemic control over 24 hours in patients with T2DM inadequately controlled with metformin
Kaj Stenlöf, Itamar Raz, Joel Neutel, Shoba Ravichandran, Niklas Berglind & Roland Chen
Pages: 2355-2363
Published online: 31 Aug 2010
AbstractforSaxagliptin and metformin XR combination therapy provides glycemic control over 24 hours in patients with T2DM inadequately controlled with metformin | Full Text | References | PDF (378.7 KB)
  • 923 Views
  • 23 CrossRef citations
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Article
Potential economic impact of increasing low dose aspirin usage on CVD in the US
Stephanie C. Manson, Agnes Benedict, Feng Pan, Kim U. Wittrup-Jensen & A. Mark Fendrick
Pages: 2365-2373
Published online: 26 Aug 2010
AbstractforPotential economic impact of increasing low dose aspirin usage on CVD in the US | Full Text | References | PDF (301.6 KB) | Supplemental
  • 320 Views
  • 7 CrossRef citations
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Article
Diclofenac potassium liquid-filled soft gelatin capsules for the treatment of postbunionectomy pain
Stephen E. Daniels, Douglas R. Baum, Francis Clark, Michael H. Golf, Mark E. McDonnell & Stephen E. Boesing
Pages: 2375-2384
Published online: 31 Aug 2010
AbstractforDiclofenac potassium liquid-filled soft gelatin capsules for the treatment of postbunionectomy pain | Full Text | References | PDF (266.7 KB)
  • 236 Views
  • 23 CrossRef citations
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Article
Effect of ustekinumab on physical function and health-related quality of life in patients with psoriatic arthritis: a randomized, placebo-controlled, phase II trial
Arthur Kavanaugh, Alan Menter, Alan Mendelsohn, Yaung-Kaung Shen, Seina Lee & Alice B. Gottlieb
Pages: 2385-2392
Published online: 13 Sep 2010
AbstractforEffect of ustekinumab on physical function and health-related quality of life in patients with psoriatic arthritis: a randomized, placebo-controlled, phase II trial | Full Text | References | PDF (234.1 KB)
  • 797 Views
  • 44 CrossRef citations
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Article
Epoetin theta: efficacy and safety of IV administration in anaemic haemodialysis patients in the maintenance phase in comparison to epoetin beta
B. Gertz, E. Kohler, P. Kes, A. Essaian, P. Bias, A. Buchner & R. Elsässer
Pages: 2393-2402
Published online: 02 Sep 2010
AbstractforEpoetin theta: efficacy and safety of IV administration in anaemic haemodialysis patients in the maintenance phase in comparison to epoetin beta | Full Text | References | PDF (178.9 KB)
  • 290 Views
  • 9 CrossRef citations
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Article
Reasons for discontinuation and continuation of antipsychotics in the treatment of schizophrenia from patient and clinician perspectives
Haya Ascher-Svanum, Allen W. Nyhuis, Virginia Stauffer, Bruce J. Kinon, Douglas E. Faries, Glenn A. Phillips, Kory Schuh, A. George Awad, Richard Keefe & Dieter Naber
Pages: 2403-2410
Published online: 02 Sep 2010
AbstractforReasons for discontinuation and continuation of antipsychotics in the treatment of schizophrenia from patient and clinician perspectives | Full Text | References | PDF (117.3 KB)
  • 763 Views
  • 37 CrossRef citations
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Review

Review Article
The effect of pregabalin on pain-related sleep interference in diabetic peripheral neuropathy or postherpetic neuralgia: a review of nine clinical trials
Thomas Roth, Robert van Seventer & T. Kevin Murphy
Pages: 2411-2419
Published online: 02 Sep 2010
AbstractforThe effect of pregabalin on pain-related sleep interference in diabetic peripheral neuropathy or postherpetic neuralgia: a review of nine clinical trials | Full Text | References | PDF (165.4 KB)
  • 762 Views
  • 42 CrossRef citations
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Review Article
Adherence to controller therapy for chronic obstructive pulmonary disease: a review
Meaghan St. Charles, Christopher M. Blanchette, Harris Silver, Danielle Lavallee, Anand A. Dalal & Douglas Mapel
Pages: 2421-2429
Published online: 03 Sep 2010
AbstractforAdherence to controller therapy for chronic obstructive pulmonary disease: a review | Full Text | References | PDF (159.7 KB)
  • 727 Views
  • 36 CrossRef citations
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Review Article
A clinical and health economic review of a prefilled insulin pen
L. Niskanen
Pages: 2431-2439
Published online: 03 Sep 2010
AbstractforA clinical and health economic review of a prefilled insulin pen | Full Text | References | PDF (157.4 KB)
  • 449 Views
  • 5 CrossRef citations
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Brief Report

Brief Report
The ACTION study: methodology of a trial to evaluate safety and efficacy of a higher dose rivastigmine transdermal patch in severe Alzheimer's disease
Martin R. Farlow, George Grossberg, Serge Gauthier, Xiangyi Meng & Jason T. Olin
Pages: 2441-2447
Published online: 10 Sep 2010
AbstractforThe ACTION study: methodology of a trial to evaluate safety and efficacy of a higher dose rivastigmine transdermal patch in severe Alzheimer's disease | Full Text | References | PDF (177.6 KB)
  • 617 Views
  • 21 CrossRef citations
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Original Article

Article
Burden on UK secondary care of rotavirus disease and seasonal infections in children
Christopher Morgan, Nick Adlard, Stuart Carroll & Latha Parvataneni
Pages: 2449-2455
Published online: 06 Sep 2010
AbstractforBurden on UK secondary care of rotavirus disease and seasonal infections in children | Full Text | References | PDF (475.4 KB)
  • 405 Views
  • 12 CrossRef citations
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Brief Report

Brief Report
Comparative survival and cost of antifungal therapy: posaconazole versus standard antifungals in the treatment of refractory invasive aspergillosis
Raoul Herbrecht, Srinivasan Rajagopalan, Robert Danna & George Papadopoulos
Pages: 2457-2464
Published online: 07 Sep 2010
AbstractforComparative survival and cost of antifungal therapy: posaconazole versus standard antifungals in the treatment of refractory invasive aspergillosis | Full Text | References | PDF (319.1 KB)
  • 328 Views
  • 5 CrossRef citations
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Review

Review Article
Clinical burden of venous thromboembolism
Andras Ruppert, Michael Lees & Thomas Steinle
Pages: 2465-2473
Published online: 08 Sep 2010
AbstractforClinical burden of venous thromboembolism | Full Text | References | PDF (179 KB)
  • 557 Views
  • 32 CrossRef citations
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Original Article

Article
Direct and indirect costs of employees with treatment-resistant and non-treatment-resistant major depressive disorder
Jasmina I. Ivanova, Howard G. Birnbaum, Yohanne Kidolezi, Ganesh Subramanian, Sajjad A. Khan & Michael D. Stensland
Pages: 2475-2484
Published online: 08 Sep 2010
AbstractforDirect and indirect costs of employees with treatment-resistant and non-treatment-resistant major depressive disorder | Full Text | References | PDF (131 KB)
  • 919 Views
  • 86 CrossRef citations
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Article
Cost-effectiveness of statin therapy for vascular event prevention in adults with elevated C-reactive protein: implications of JUPITER
Julia F. Slejko, Robert L. Page II & Patrick W. Sullivan
Pages: 2485-2497
Published online: 10 Sep 2010
AbstractforCost-effectiveness of statin therapy for vascular event prevention in adults with elevated C-reactive protein: implications of JUPITER | Full Text | References | PDF (352.3 KB)
  • 407 Views
  • 14 CrossRef citations
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Article
Healthcare resource utilization, adherence and persistence with antipsychotic therapy among schizophrenia patients with vs. without pre-existing metabolic syndrome
Lizheng Shi, Yingnan Zhao, Vivian Fonseca, Haya Ascher-Svanum, Yi-Ju Chiang & Daniel Winstead
Pages: 2499-2506
Published online: 10 Sep 2010
AbstractforHealthcare resource utilization, adherence and persistence with antipsychotic therapy among schizophrenia patients with vs. without pre-existing metabolic syndrome | Full Text | References | PDF (152.8 KB)
  • 213 Views
  • 4 CrossRef citations
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Article
Opioid use and healthcare costs among patients with DPNP initiating duloxetine versus other treatments
S. Chen, N. Wu, K. Fraser, L. Boulanger & Y. Zhao
Pages: 2507-2516
Published online: 13 Sep 2010
AbstractforOpioid use and healthcare costs among patients with DPNP initiating duloxetine versus other treatments | Full Text | References | PDF (175.9 KB)
  • 279 Views
  • 8 CrossRef citations
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Editorial

Editorial
Ezetimibe in diabetes: more than cholesterol lowering?
Maria Sarigianni, Niki Katsiki & Dimitri P Mikhailidis
Pages: 2517-2520
Published online: 15 Sep 2010
AbstractforEzetimibe in diabetes: more than cholesterol lowering? | Full Text | References | PDF (87 KB)
  • 3638 Views
  • 14 CrossRef citations
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